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Conserved domains on  [gi|1770726349|ref|NP_001362476|]
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target of Nesh-SH3 isoform 8 precursor [Homo sapiens]

Protein Classification

fibronectin type III domain-containing protein( domain architecture ID 10414115)

fibronectin type III (FN3) domain-containing protein may be involved in specific interactions with other molecules through its FN3 domain

Gene Ontology:  GO:0005515
PubMed:  8981327

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
771-1268 6.15e-16

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 84.60  E-value: 6.15e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  771 SAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVP-ATILEPV-------------LRTEASG-------TTAAPKVPQR--- 826
Cdd:PHA03247  2490 FAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPdEPVGEPVhprmltwirgleeLASDDAGdpppplpPAAPPAAPDRsvp 2569
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  827 THRPHPKPKTTLSPEELQTELVP---ATIFEPVSPIKEAPGTTfvPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPK 903
Cdd:PHA03247  2570 PPRPAPRPSEPAVTSRARRPDAPpqsARPRAPVDDRGDPRGPA--PPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP 2647
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  904 TtpsPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTP-----RPEAPESKPVPtaelkpvtlRTETW 978
Cdd:PHA03247  2648 P---PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltslaDPPPPPPTPEP---------APHAL 2715
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  979 VT-TQAPKTSQRTRRPRPKTKTTPSPevpqtklvPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTR 1057
Cdd:PHA03247  2716 VSaTPLPPGPAAARQASPALPAAPAP--------PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPA 2787
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1058 RPRPRPKTTS--SPEVPQNKSVSVTGFEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESqPVSDVLESVTLSTES 1135
Cdd:PHA03247  2788 VASLSESRESlpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP-LGGSVAPGGDVRRRP 2866
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1136 PKETIAPAKTDYVYPTAKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPK 1215
Cdd:PHA03247  2867 PSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1770726349 1216 TSPRPRIPQTQPVPK------VPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVS 1268
Cdd:PHA03247  2947 TDPAGAGEPSGAVPQpwlgalVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVS 3005
PHA03247 super family cl33720
large tegument protein UL36; Provisional
471-973 1.93e-12

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 73.05  E-value: 1.93e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  471 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE--RTTSAGTITPKISKSPEPTWTT 548
Cdd:PHA03247  2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGdpRGPAPPSPLPPDTHAPDPPPPS 2630
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  549 PAPGKTQfiSLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVP 628
Cdd:PHA03247  2631 PSPAANE--PDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTP 2708
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  629 KSKPalePATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPP--KQLLPKPQTTAEPD--MPPTKSVSEPVPFETE 704
Cdd:PHA03247  2709 EPAP---HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPggPARPARPPTTAGPPapAPPAAPAAGPPRRLTR 2785
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  705 APSMTIVPTTDIEP-----------VTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDfGPITPGtssAP 773
Cdd:PHA03247  2786 PAVASLSESRESLPspwdpadppaaVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG-GSVAPG---GD 2861
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  774 TTTTKRTRRPHPKPKTTPHPEV-----PQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEE------ 842
Cdd:PHA03247  2862 VRRRPPSRSPAAKPAAPARPPVrrlarPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPpprpqp 2941
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  843 -LQTELVPATIFEPvSPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAP-----ETKPV 916
Cdd:PHA03247  2942 pLAPTTDPAGAGEP-SGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSlalheETDPP 3020
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1770726349  917 PATVLEpvTLRPEASTTLASKTSQRTRRPRLRTKTTPRPEAPESKPVPTAELKPVTL 973
Cdd:PHA03247  3021 PVSLKQ--TLWPPDDTEDSDADSLFDSDSERSDLEALDPLPPEPHDPFAHEPDPATP 3075
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
1550-1641 1.30e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 56.74  E-value: 1.30e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1550 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 1627
Cdd:cd00063      2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79
                           90
                   ....*....|....
gi 1770726349 1628 LGEGPVSNTVAFST 1641
Cdd:cd00063     80 GGESPPSESVTVTT 93
PRK10263 super family cl35903
DNA translocase FtsK; Provisional
1151-1403 1.17e-05

DNA translocase FtsK; Provisional


The actual alignment was detected with superfamily member PRK10263:

Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 50.47  E-value: 1.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1151 TAKAPLW--PEEPKTEVVESITYVSEPPETTLETSPLPSqsitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPV 1228
Cdd:PRK10263   327 TTATQSWaaPVEPVTQTPPVASVDVPPAQPTVAWQPVPG-----PQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPV 401
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1229 PkvPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPVLQPVTfrfEPPKTTIAPLETRGiPFIPMISPSPsq 1308
Cdd:PRK10263   402 Q--PQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA---EEQQSTFAPQSTYQ-TEQTYQQPAA-- 473
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1309 eelQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD---------KPHIRPVLNRTTTRPTRPKPS-- 1377
Cdd:PRK10263   474 ---QEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRARereqlaawyQPIPEPVKEPEPIKSSLKAPSva 550
                          250       260       270
                   ....*....|....*....|....*....|..
gi 1770726349 1378 ------GMPSGNGVGTGVKQAPRPSGADRNVS 1403
Cdd:PRK10263   551 avppveAAAAVSPLASGVKKATLATGAAATVA 582
FN3 super family cl21522
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
116-195 6.52e-04

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


The actual alignment was detected with superfamily member pfam00041:

Pssm-ID: 473895 [Multi-domain]  Cd Length: 85  Bit Score: 40.48  E-value: 6.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  116 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPND-RFYTIRYREKDKEKKWIFQICPATET--IVENLKPNTVYEF 192
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71

                   ...
gi 1770726349  193 GVK 195
Cdd:pfam00041   72 RVQ 74
FN3 super family cl27307
Fibronectin type 3 domain [General function prediction only];
1367-1646 7.50e-04

Fibronectin type 3 domain [General function prediction only];


The actual alignment was detected with superfamily member COG3401:

Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 44.22  E-value: 7.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1367 TTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGI 1446
Cdd:COG3401     48 TKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATT 127
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1447 ISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNS--- 1523
Cdd:COG3401    128 ATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTyyy 207
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1524 -PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQMT 1602
Cdd:COG3401    208 rVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATV 282
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1770726349 1603 NQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 1646
Cdd:COG3401    283 TTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
PHA03247 super family cl33720
large tegument protein UL36; Provisional
257-580 3.27e-03

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 3.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  257 DSAKSPEKAPlggvilvHLIIPGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVP 336
Cdd:PHA03247  2703 PPPPTPEPAP-------HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAP 2775
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  337 RSTKPTTSSALDVSETTLVL----SKRTPETLQTILIPQFELPLSTLAPKSLPEFPEAKTPFPFEKPRGTLASSEKP--W 410
Cdd:PHA03247  2776 AAGPPRRLTRPAVASLSESReslpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggS 2855
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  411 IVPTAKISEDSKVLQPQTatydvfsSPTTSDEPEISdsytatsdRILDSIPPKTSRTLEQPRATLAPSETPFVPQKleif 490
Cdd:PHA03247  2856 VAPGGDVRRRPPSRSPAA-------KPAAPARPPVR--------RLARPAVSRSTESFALPPDQPERPPQPQAPPP---- 2916
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  491 tsPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKperTTSAGTITPKIsksPEPTWTTPAPGKTQFISLKpkiplSPEVT 570
Cdd:PHA03247  2917 --PQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTD---PAGAGEPSGAV---PQPWLGALVPGRVAVPRFR-----VPQPA 2983
                          330
                   ....*....|
gi 1770726349  571 HTKPAPEPQT 580
Cdd:PHA03247  2984 PSREAPASST 2993
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
771-1268 6.15e-16

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 84.60  E-value: 6.15e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  771 SAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVP-ATILEPV-------------LRTEASG-------TTAAPKVPQR--- 826
Cdd:PHA03247  2490 FAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPdEPVGEPVhprmltwirgleeLASDDAGdpppplpPAAPPAAPDRsvp 2569
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  827 THRPHPKPKTTLSPEELQTELVP---ATIFEPVSPIKEAPGTTfvPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPK 903
Cdd:PHA03247  2570 PPRPAPRPSEPAVTSRARRPDAPpqsARPRAPVDDRGDPRGPA--PPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP 2647
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  904 TtpsPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTP-----RPEAPESKPVPtaelkpvtlRTETW 978
Cdd:PHA03247  2648 P---PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltslaDPPPPPPTPEP---------APHAL 2715
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  979 VT-TQAPKTSQRTRRPRPKTKTTPSPevpqtklvPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTR 1057
Cdd:PHA03247  2716 VSaTPLPPGPAAARQASPALPAAPAP--------PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPA 2787
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1058 RPRPRPKTTS--SPEVPQNKSVSVTGFEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESqPVSDVLESVTLSTES 1135
Cdd:PHA03247  2788 VASLSESRESlpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP-LGGSVAPGGDVRRRP 2866
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1136 PKETIAPAKTDYVYPTAKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPK 1215
Cdd:PHA03247  2867 PSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1770726349 1216 TSPRPRIPQTQPVPK------VPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVS 1268
Cdd:PHA03247  2947 TDPAGAGEPSGAVPQpwlgalVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVS 3005
PHA03247 PHA03247
large tegument protein UL36; Provisional
471-973 1.93e-12

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 73.05  E-value: 1.93e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  471 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE--RTTSAGTITPKISKSPEPTWTT 548
Cdd:PHA03247  2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGdpRGPAPPSPLPPDTHAPDPPPPS 2630
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  549 PAPGKTQfiSLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVP 628
Cdd:PHA03247  2631 PSPAANE--PDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTP 2708
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  629 KSKPalePATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPP--KQLLPKPQTTAEPD--MPPTKSVSEPVPFETE 704
Cdd:PHA03247  2709 EPAP---HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPggPARPARPPTTAGPPapAPPAAPAAGPPRRLTR 2785
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  705 APSMTIVPTTDIEP-----------VTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDfGPITPGtssAP 773
Cdd:PHA03247  2786 PAVASLSESRESLPspwdpadppaaVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG-GSVAPG---GD 2861
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  774 TTTTKRTRRPHPKPKTTPHPEV-----PQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEE------ 842
Cdd:PHA03247  2862 VRRRPPSRSPAAKPAAPARPPVrrlarPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPpprpqp 2941
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  843 -LQTELVPATIFEPvSPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAP-----ETKPV 916
Cdd:PHA03247  2942 pLAPTTDPAGAGEP-SGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSlalheETDPP 3020
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1770726349  917 PATVLEpvTLRPEASTTLASKTSQRTRRPRLRTKTTPRPEAPESKPVPTAELKPVTL 973
Cdd:PHA03247  3021 PVSLKQ--TLWPPDDTEDSDADSLFDSDSERSDLEALDPLPPEPHDPFAHEPDPATP 3075
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
1550-1641 1.30e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 56.74  E-value: 1.30e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1550 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 1627
Cdd:cd00063      2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79
                           90
                   ....*....|....
gi 1770726349 1628 LGEGPVSNTVAFST 1641
Cdd:cd00063     80 GGESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
1551-1631 1.84e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 50.31  E-value: 1.84e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  1551 PPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV-ISRENGSFSGKNKSIQMTNQTFS-TVENLKPNTSYEFQVKPKNPL 1628
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGITGYIVgYRVEYREEGSEWKEVNVTPSSTSyTLTGLKPGTEYEFRVRAVNGA 80

                    ...
gi 1770726349  1629 GEG 1631
Cdd:smart00060   81 GEG 83
PRK10263 PRK10263
DNA translocase FtsK; Provisional
1151-1403 1.17e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 50.47  E-value: 1.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1151 TAKAPLW--PEEPKTEVVESITYVSEPPETTLETSPLPSqsitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPV 1228
Cdd:PRK10263   327 TTATQSWaaPVEPVTQTPPVASVDVPPAQPTVAWQPVPG-----PQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPV 401
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1229 PkvPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPVLQPVTfrfEPPKTTIAPLETRGiPFIPMISPSPsq 1308
Cdd:PRK10263   402 Q--PQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA---EEQQSTFAPQSTYQ-TEQTYQQPAA-- 473
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1309 eelQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD---------KPHIRPVLNRTTTRPTRPKPS-- 1377
Cdd:PRK10263   474 ---QEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRARereqlaawyQPIPEPVKEPEPIKSSLKAPSva 550
                          250       260       270
                   ....*....|....*....|....*....|..
gi 1770726349 1378 ------GMPSGNGVGTGVKQAPRPSGADRNVS 1403
Cdd:PRK10263   551 avppveAAAAVSPLASGVKKATLATGAAATVA 582
fn3 pfam00041
Fibronectin type III domain;
1551-1634 5.22e-05

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 43.56  E-value: 5.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1551 PPTNLTVVTVEgcPSFVILDWEKP--LNDTVTEYEVISRENGSFSGKNkSIQMTNQTFS-TVENLKPNTSYEFQVKPKNP 1627
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPpdGNGPITGYEVEYRPKNSGEPWN-EITVPGTTTSvTLTGLKPGTEYEVRVQAVNG 78

                   ....*..
gi 1770726349 1628 LGEGPVS 1634
Cdd:pfam00041   79 GGEGPPS 85
fn3 pfam00041
Fibronectin type III domain;
116-195 6.52e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 40.48  E-value: 6.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  116 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPND-RFYTIRYREKDKEKKWIFQICPATET--IVENLKPNTVYEF 192
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71

                   ...
gi 1770726349  193 GVK 195
Cdd:pfam00041   72 RVQ 74
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
117-195 6.70e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 40.29  E-value: 6.70e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349   117 PLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPNDRFYTIRYREKDKEKKWIFQICPA----TETIVENLKPNTVYEF 192
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTEYEF 72

                    ...
gi 1770726349   193 GVK 195
Cdd:smart00060   73 RVR 75
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1367-1646 7.50e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 44.22  E-value: 7.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1367 TTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGI 1446
Cdd:COG3401     48 TKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATT 127
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1447 ISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNS--- 1523
Cdd:COG3401    128 ATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTyyy 207
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1524 -PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQMT 1602
Cdd:COG3401    208 rVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATV 282
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1770726349 1603 NQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 1646
Cdd:COG3401    283 TTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1545-1689 9.52e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 43.84  E-value: 9.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1545 TSPPQnPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV--ISRENGSFSGKNKSIqmtNQTFSTVENLKPNTSYEFQV 1622
Cdd:COG3401    324 LTPPA-APSGLTATAVG--SSSITLSWTASSDADVTGYNVyrSTSGGGTYTKIAETV---TTTSYTDTGLTPGTTYYYKV 397
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1770726349 1623 KPKNPLG-EGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVG 1689
Cdd:COG3401    398 TAVDAAGnESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTG 465
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
928-1254 3.04e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 42.25  E-value: 3.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  928 PEASTTLASKTSQRT-RRPRLRTKTTPRPEAPESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPSPEVP 1006
Cdd:pfam17823   66 APAPVTLTKGTSAAHlNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSEAFSAP 145
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1007 QTKlVPSTdlePGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPKTTS----SPEVPQNKSVSVTGF 1082
Cdd:pfam17823  146 RAA-ACRA---NASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSApatlTPARGISTAATATGH 221
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1083 EPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESQPVSDVLESVTLSTESP-KETIAPAKTDYVYPTAKAPLWPEEP 1161
Cdd:pfam17823  222 PAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPhARRLSPAKHMPSDTMARNPAAPMGA 301
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1162 KTEVVESITYVSEPPETTlETSPLPSQSITLPSPDEPQ-----------TEPAPKQTPRAPPKP--KTSPRPRI----PQ 1224
Cdd:pfam17823  302 QAQGPIIQVSTDQPVHNT-AGEPTPSPSNTTLEPNTPKsvastnlavvtTTKAQAKEPSASPVPvlHTSMIPEVeatsPT 380
                          330       340       350
                   ....*....|....*....|....*....|
gi 1770726349 1225 TQPVPKVPQRVTAKPKTSPSPEVSYTTPAP 1254
Cdd:pfam17823  381 TQPSPLLPTQGAAGPGILLAPEQVATEATA 410
PHA03247 PHA03247
large tegument protein UL36; Provisional
257-580 3.27e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 3.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  257 DSAKSPEKAPlggvilvHLIIPGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVP 336
Cdd:PHA03247  2703 PPPPTPEPAP-------HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAP 2775
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  337 RSTKPTTSSALDVSETTLVL----SKRTPETLQTILIPQFELPLSTLAPKSLPEFPEAKTPFPFEKPRGTLASSEKP--W 410
Cdd:PHA03247  2776 AAGPPRRLTRPAVASLSESReslpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggS 2855
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  411 IVPTAKISEDSKVLQPQTatydvfsSPTTSDEPEISdsytatsdRILDSIPPKTSRTLEQPRATLAPSETPFVPQKleif 490
Cdd:PHA03247  2856 VAPGGDVRRRPPSRSPAA-------KPAAPARPPVR--------RLARPAVSRSTESFALPPDQPERPPQPQAPPP---- 2916
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  491 tsPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKperTTSAGTITPKIsksPEPTWTTPAPGKTQFISLKpkiplSPEVT 570
Cdd:PHA03247  2917 --PQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTD---PAGAGEPSGAV---PQPWLGALVPGRVAVPRFR-----VPQPA 2983
                          330
                   ....*....|
gi 1770726349  571 HTKPAPEPQT 580
Cdd:PHA03247  2984 PSREAPASST 2993
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
116-195 3.50e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.63  E-value: 3.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  116 KPLQLVVGTLTPSSVFLSWgfliNPHHDWTLPSHcpndrFYTIRYREKDKE--KKWIFQICPATETIVENLKPNTVYEFG 193
Cdd:cd00063      3 PPTNLRVTDVTSTSVTLSW----TPPEDDGGPIT-----GYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFR 73

                   ..
gi 1770726349  194 VK 195
Cdd:cd00063     74 VR 75
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
771-1268 6.15e-16

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 84.60  E-value: 6.15e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  771 SAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVP-ATILEPV-------------LRTEASG-------TTAAPKVPQR--- 826
Cdd:PHA03247  2490 FAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPdEPVGEPVhprmltwirgleeLASDDAGdpppplpPAAPPAAPDRsvp 2569
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  827 THRPHPKPKTTLSPEELQTELVP---ATIFEPVSPIKEAPGTTfvPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPK 903
Cdd:PHA03247  2570 PPRPAPRPSEPAVTSRARRPDAPpqsARPRAPVDDRGDPRGPA--PPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP 2647
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  904 TtpsPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTP-----RPEAPESKPVPtaelkpvtlRTETW 978
Cdd:PHA03247  2648 P---PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltslaDPPPPPPTPEP---------APHAL 2715
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  979 VT-TQAPKTSQRTRRPRPKTKTTPSPevpqtklvPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTR 1057
Cdd:PHA03247  2716 VSaTPLPPGPAAARQASPALPAAPAP--------PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPA 2787
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1058 RPRPRPKTTS--SPEVPQNKSVSVTGFEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESqPVSDVLESVTLSTES 1135
Cdd:PHA03247  2788 VASLSESRESlpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP-LGGSVAPGGDVRRRP 2866
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1136 PKETIAPAKTDYVYPTAKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPK 1215
Cdd:PHA03247  2867 PSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1770726349 1216 TSPRPRIPQTQPVPK------VPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVS 1268
Cdd:PHA03247  2947 TDPAGAGEPSGAVPQpwlgalVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVS 3005
PHA03247 PHA03247
large tegument protein UL36; Provisional
628-1018 3.91e-14

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 78.44  E-value: 3.91e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  628 PKSKPALEPATiqPEPLVPTT--ASKPSERPKTT--HRPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTKSVSEPVPFET 703
Cdd:PHA03247  2553 PPLPPAAPPAA--PDRSVPPPrpAPRPSEPAVTSraRRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPS 2630
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  704 EAPSMTIVPTTDIEPVTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDFGPITPGTSSA--PTTTTKRTR 781
Cdd:PHA03247  2631 PSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLAdpPPPPPTPEP 2710
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  782 RPHPKPKTTPHPEVPQT--KLVPATILEPVLRTEASGTT--------AAPKVPQRTHRPHPK--PKTTLSPEELQTELVP 849
Cdd:PHA03247  2711 APHALVSATPLPPGPAAarQASPALPAAPAPPAVPAGPAtpggparpARPPTTAGPPAPAPPaaPAAGPPRRLTRPAVAS 2790
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  850 ATIFEPVSPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAPETKPVPATvlePVTLRPE 929
Cdd:PHA03247  2791 LSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGG---DVRRRPP 2867
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  930 ASTTlASKTSQRTRRPRLRTKTTPRPEAPESKPVPTAELKPVTlrtetwvTTQAPKTSQRTRRPRPKTKTTPSPEV---P 1006
Cdd:PHA03247  2868 SRSP-AAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPP-------QPQAPPPPQPQPQPPPPPQPQPPPPPpprP 2939
                          410
                   ....*....|..
gi 1770726349 1007 QTKLVPSTDLEP 1018
Cdd:PHA03247  2940 QPPLAPTTDPAG 2951
PHA03247 PHA03247
large tegument protein UL36; Provisional
471-973 1.93e-12

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 73.05  E-value: 1.93e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  471 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE--RTTSAGTITPKISKSPEPTWTT 548
Cdd:PHA03247  2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGdpRGPAPPSPLPPDTHAPDPPPPS 2630
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  549 PAPGKTQfiSLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVP 628
Cdd:PHA03247  2631 PSPAANE--PDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTP 2708
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  629 KSKPalePATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPP--KQLLPKPQTTAEPD--MPPTKSVSEPVPFETE 704
Cdd:PHA03247  2709 EPAP---HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPggPARPARPPTTAGPPapAPPAAPAAGPPRRLTR 2785
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  705 APSMTIVPTTDIEP-----------VTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDfGPITPGtssAP 773
Cdd:PHA03247  2786 PAVASLSESRESLPspwdpadppaaVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG-GSVAPG---GD 2861
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  774 TTTTKRTRRPHPKPKTTPHPEV-----PQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEE------ 842
Cdd:PHA03247  2862 VRRRPPSRSPAAKPAAPARPPVrrlarPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPpprpqp 2941
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  843 -LQTELVPATIFEPvSPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAP-----ETKPV 916
Cdd:PHA03247  2942 pLAPTTDPAGAGEP-SGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSlalheETDPP 3020
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1770726349  917 PATVLEpvTLRPEASTTLASKTSQRTRRPRLRTKTTPRPEAPESKPVPTAELKPVTL 973
Cdd:PHA03247  3021 PVSLKQ--TLWPPDDTEDSDADSLFDSDSERSDLEALDPLPPEPHDPFAHEPDPATP 3075
PHA03247 PHA03247
large tegument protein UL36; Provisional
388-793 1.14e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.80  E-value: 1.14e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  388 PEAKTPFPFEKPRGTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILdsiPPKTSRT 467
Cdd:PHA03247  2593 PQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVS---RPRRARR 2669
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  468 LEQPRATLAPSETPFVPQ------KLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPrpkpprtkperTTSAGTITPKISKS 541
Cdd:PHA03247  2670 LGRAAQASSPPQRPRRRAarptvgSLTSLADPPPPPPTPEPAPHALVSATPLPPG-----------PAAARQASPALPAA 2738
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  542 PEPtwttPAPGKTQFISLKPKIPLSPEVTHTKPAPEPqtllpsqstigPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKT 621
Cdd:PHA03247  2739 PAP----PAVPAGPATPGGPARPARPPTTAGPPAPAP-----------PAAPAAGPPRRLTRPAVASLSESRESLPSPWD 2803
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  622 TPSPEVPKSKP-ALEPATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGS----------KPPKQllPKPQTTAEPDMP 690
Cdd:PHA03247  2804 PADPPAAVLAPaAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGsvapggdvrrRPPSR--SPAAKPAAPARP 2881
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  691 PTKSVSEPV-----------PFETEAPSMTIVPTTDIEPVTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTK 759
Cdd:PHA03247  2882 PVRRLARPAvsrstesfalpPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQ 2961
                          410       420       430
                   ....*....|....*....|....*....|....
gi 1770726349  760 LDFGPITPGTSSAPTTTTKRTRRPHPKPKTTPHP 793
Cdd:PHA03247  2962 PWLGALVPGRVAVPRFRVPQPAPSREAPASSTPP 2995
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
1550-1641 1.30e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 56.74  E-value: 1.30e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1550 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 1627
Cdd:cd00063      2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79
                           90
                   ....*....|....
gi 1770726349 1628 LGEGPVSNTVAFST 1641
Cdd:cd00063     80 GGESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
1551-1631 1.84e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 50.31  E-value: 1.84e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  1551 PPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV-ISRENGSFSGKNKSIQMTNQTFS-TVENLKPNTSYEFQVKPKNPL 1628
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGITGYIVgYRVEYREEGSEWKEVNVTPSSTSyTLTGLKPGTEYEFRVRAVNGA 80

                    ...
gi 1770726349  1629 GEG 1631
Cdd:smart00060   81 GEG 83
PRK10263 PRK10263
DNA translocase FtsK; Provisional
694-1293 3.92e-06

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 52.01  E-value: 3.92e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  694 SVSEPVPFETEAPSMTIVPTTDIEPVTvrTEATVTTLAPKTSQRTRtrrprpKHKTTPRPETLQTKLDFGPitpgTSSAP 773
Cdd:PRK10263   315 PITEPVAVAAAATTATQSWAAPVEPVT--QTPPVASVDVPPAQPTV------AWQPVPGPQTGEPVIAPAP----EGYPQ 382
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  774 TTTTKRTRRPHPKPKTTPHPEVPQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVPATIF 853
Cdd:PRK10263   383 QSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTY 462
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  854 EPVSPIKE--APGTTFVPVTDLEPVTFRTEIPATTlATKTSKRTRPPRPRPKTTPSPQ----APETKPVPATVLEPVTLR 927
Cdd:PRK10263   463 QTEQTYQQpaAQEPLYQQPQPVEQQPVVEPEPVVE-ETKPARPPLYYFEEVEEKRAREreqlAAWYQPIPEPVKEPEPIK 541
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  928 PEASTTLASKTSqrtrrprlrtkttPRPEAPESKPVpTAELKPVTLRTETWVTTQAPKTSQRTR-RPRPKTKTTPSPEVP 1006
Cdd:PRK10263   542 SSLKAPSVAAVP-------------PVEAAAAVSPL-ASGVKKATLATGAAATVAAPVFSLANSgGPRPQVKEGIGPQLP 607
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1007 QtklvpstdlepgtlrteaPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPKTTS----------SPEVPQNKS 1076
Cdd:PRK10263   608 R------------------PKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQynddeidamqQDELARQFA 669
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1077 VSVTGFEPVVHSTDAPGTT--------------FALTELQTLILKPVTSP---SLEMTESQPVSDVLEsvtlstESPKEt 1139
Cdd:PRK10263   670 QTQQQRYGEQYQHDVPVNAedadaaaeaelarqFAQTQQQRYSGEQPAGAnpfSLDDFEFSPMKALLD------DGPHE- 742
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1140 iaPAKTDYVYPTAKaPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQsitlPSPDEPQTEPAPKQTPRAPPKPkTSPR 1219
Cdd:PRK10263   743 --PLFTPIVEPVQQ-PQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQ----PQYQQPQQPVAPQPQYQQPQQP-VAPQ 814
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1770726349 1220 PRIPQTQPvPKVPQRVTAKPKTSPSpevsyttPAPKDVLLpHKPYPEVSQSEPVLQPVT-----FRFEPPKTTIAPLET 1293
Cdd:PRK10263   815 PQYQQPQQ-PVAPQPQYQQPQQPVA-------PQPQDTLL-HPLLMRNGDSRPLHKPTTplpslDLLTPPPSEVEPVDT 884
PRK10263 PRK10263
DNA translocase FtsK; Provisional
1151-1403 1.17e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 50.47  E-value: 1.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1151 TAKAPLW--PEEPKTEVVESITYVSEPPETTLETSPLPSqsitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPV 1228
Cdd:PRK10263   327 TTATQSWaaPVEPVTQTPPVASVDVPPAQPTVAWQPVPG-----PQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPV 401
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1229 PkvPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPVLQPVTfrfEPPKTTIAPLETRGiPFIPMISPSPsq 1308
Cdd:PRK10263   402 Q--PQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA---EEQQSTFAPQSTYQ-TEQTYQQPAA-- 473
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1309 eelQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD---------KPHIRPVLNRTTTRPTRPKPS-- 1377
Cdd:PRK10263   474 ---QEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRARereqlaawyQPIPEPVKEPEPIKSSLKAPSva 550
                          250       260       270
                   ....*....|....*....|....*....|..
gi 1770726349 1378 ------GMPSGNGVGTGVKQAPRPSGADRNVS 1403
Cdd:PRK10263   551 avppveAAAAVSPLASGVKKATLATGAAATVA 582
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
1108-1377 2.75e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 49.30  E-value: 2.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1108 PVTSPSLEMTESQPVSDVLESvtlstESPKETIAPAKTDYVYPTAKaplwPEEPKTEVVESITYVSEPPEttletspLPS 1187
Cdd:PTZ00449   520 PPKAPGDKEGEEGEHEDSKES-----DEPKEGGKPGETKEGEVGKK----PGPAKEHKPSKIPTLSKKPE-------FPK 583
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1188 QSitlPSPDEPQtEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA--KPKTSPSPEVSYTTPAPKDVLLPHKPYP 1265
Cdd:PTZ00449   584 DP---KHPKDPE-EPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESpkSPKRPPPPQRPSSPERPEGPKIIKSPKP 659
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1266 EVSQSEPvlqpvtfrFEPPKTTiapletrgiPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPhr 1345
Cdd:PTZ00449   660 PKSPKPP--------FDPKFKE---------KFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRP-- 720
                          250       260       270
                   ....*....|....*....|....*....|..
gi 1770726349 1346 fYTTVRPRTSDKPHIRPvlnrttTRPTRPKPS 1377
Cdd:PTZ00449   721 -LPPKLPRDEEFPFEPI------GDPDAEQPD 745
PHA03247 PHA03247
large tegument protein UL36; Provisional
1154-1515 2.91e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.55  E-value: 2.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1154 APLWPEEPKTEVVESityvsEPPETTLETSPLPSQSitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVP---K 1230
Cdd:PHA03247  2591 APPQSARPRAPVDDR-----GDPRGPAPPSPLPPDT---HAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPgrvS 2662
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1231 VPQRVTAK--PKTSPSPEVSYTTPAPKDVLLP---------------HKPYPEVSQSEPVLQPVTFRFEPPKTTIAPLeT 1293
Cdd:PHA03247  2663 RPRRARRLgrAAQASSPPQRPRRRAARPTVGSltsladpppppptpePAPHALVSATPLPPGPAAARQASPALPAAPA-P 2741
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1294 RGIPFIPMISPSPSQEELQTTLEETDQST--QEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPVLNRTTTRP 1371
Cdd:PHA03247  2742 PAVPAGPATPGGPARPARPPTTAGPPAPAppAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1372 TRPKPSGMPSGNGVGTGVKQAPRPSGADRNV--SVDSTHPTKKPGTRRPplppRPTHPRRKPLPPNNVTGKPGSAGIISS 1449
Cdd:PHA03247  2822 ASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggSVAPGGDVRRRPPSRS----PAAKPAAPARPPVRRLARPAVSRSTES 2897
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1770726349 1450 GPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVR 1515
Cdd:PHA03247  2898 FALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPW 2963
fn3 pfam00041
Fibronectin type III domain;
1551-1634 5.22e-05

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 43.56  E-value: 5.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1551 PPTNLTVVTVEgcPSFVILDWEKP--LNDTVTEYEVISRENGSFSGKNkSIQMTNQTFS-TVENLKPNTSYEFQVKPKNP 1627
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPpdGNGPITGYEVEYRPKNSGEPWN-EITVPGTTTSvTLTGLKPGTEYEVRVQAVNG 78

                   ....*..
gi 1770726349 1628 LGEGPVS 1634
Cdd:pfam00041   79 GGEGPPS 85
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
1177-1271 8.80e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 47.50  E-value: 8.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1177 ETTLETSPLPSQ-SITLPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPK 1255
Cdd:PRK14950   357 EALLVPVPAPQPaKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTRAAI 436
                           90
                   ....*....|....*.
gi 1770726349 1256 DVLLPHKPYPEVSQSE 1271
Cdd:PRK14950   437 PVDEKPKYTPPAPPKE 452
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
985-1381 8.90e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 47.38  E-value: 8.90e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  985 KTSQRTRRPRPKTKTTPSPEVPQTKLVPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPK 1064
Cdd:PTZ00449   528 EGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRSAQRPT 607
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1065 TTSSPEVPQNKSVSVTGFEPvvHSTDAPgttfaltelqtlilKPVTSPSLEMTESQPVSDVLESVTLSTESPKETIAPAK 1144
Cdd:PTZ00449   608 RPKSPKLPELLDIPKSPKRP--ESPKSP--------------KRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKF 671
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1145 TDYVYPT-AKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPKTSP----- 1218
Cdd:PTZ00449   672 KEKFYDDyLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGDPDAEQPDDiefft 751
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1219 -----RPRIPQTQPVPKVPQRVTAKPKTspsPEVSYTTPAPKDVLL----PHKPYPEVSQSEPVLQPVTFRFEPPKTTIA 1289
Cdd:PTZ00449   752 ppeeeRTFFHETPADTPLPDILAEEFKE---EDIHAETGEPDEAMKrpdsPSEHEDKPPGDHPSLPKKRHRLDGLALSTT 828
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1290 PLETRgiPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELA-----------KTTQAPHRFYTTVRPRTSDKP 1358
Cdd:PTZ00449   829 DLESD--AGRIAKDASGKIVKLKRSKSFDDLTTVEEAEEMGAEARKIVvdddgteaddeDTHPPEEKHKSEVRRRRPPKK 906
                          410       420
                   ....*....|....*....|...
gi 1770726349 1359 HIRPVLNRTTTRPTRPKPSGMPS 1381
Cdd:PTZ00449   907 PSKPKKPSKPKKPKKPDSAFIPS 929
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
526-973 9.69e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 47.38  E-value: 9.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  526 ERTTSAGTITPKISKSPEPTWTT-----PAPGKTQFISLKPKIPLSPEVTHTKPAP-EPQTLLPSQSTIGPETPGTKPST 599
Cdd:PTZ00449   533 EHEDSKESDEPKEGGKPGETKEGevgkkPGPAKEHKPSKIPTLSKKPEFPKDPKHPkDPEEPKKPKRPRSAQRPTRPKSP 612
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  600 TLaprktkrpgrrprprprpktTPSPEVPKSKPALEPATIQPEPLVPTtaskpseRPKTTHRPDAPQIQPGSKPPKQllP 679
Cdd:PTZ00449   613 KL--------------------PELLDIPKSPKRPESPKSPKRPPPPQ-------RPSSPERPEGPKIIKSPKPPKS--P 663
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  680 KPqttaepdmpptksvsepvPFEteaPSMTIVPTTDIEPVTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPrpetLQTK 759
Cdd:PTZ00449   664 KP------------------PFD---PKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTP----FTTP 718
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  760 LDFGPITPGTSSAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLS 839
Cdd:PTZ00449   719 RPLPPKLPRDEEFPFEPIGDPDAEQPDDIEFFTPPEEERTFFHETPADTPLPDILAEEFKEEDIHAETGEPDEAMKRPDS 798
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  840 PEELQTElvpATIFEPVSPIKEAPGTTF-VPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAPETKPVpa 918
Cdd:PTZ00449   799 PSEHEDK---PPGDHPSLPKKRHRLDGLaLSTTDLESDAGRIAKDASGKIVKLKRSKSFDDLTTVEEAEEMGAEARKI-- 873
                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1770726349  919 tVLEPVTLRPEASTTLASKTSQ----RTRRPRLRTKTTPRPEAPESKPVPTAELKPVTL 973
Cdd:PTZ00449   874 -VVDDDGTEADDEDTHPPEEKHksevRRRRPPKKPSKPKKPSKPKKPKKPDSAFIPSII 931
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
1131-1465 5.28e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.16  E-value: 5.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1131 LSTESPKETIAPAKTDYVYPTAKAPLWPE-EPKTEVV--ESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQT 1207
Cdd:PHA03307    44 VSDSAELAAVTVVAGAAACDRFEPPTGPPpGPGTEAPanESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPP 123
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1208 PRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPVLQPVTFRFEPPKTT 1287
Cdd:PHA03307   124 ASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAAS 203
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1288 IAPLETRGIPFIPMISPSPS---QEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVR------PRTSDKP 1358
Cdd:PHA03307   204 PRPPRRSSPISASASSPAPApgrSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWeasgwnGPSSRPG 283
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1359 HIRPvlnRTTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVT 1438
Cdd:PHA03307   284 PASS---SSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPA 360
                          330       340
                   ....*....|....*....|....*..
gi 1770726349 1439 GKPGSAGIISSGPITTPPLRSTPRPTG 1465
Cdd:PHA03307   361 DPSSPRKRPRPSRAPSSPAASAGRPTR 387
fn3 pfam00041
Fibronectin type III domain;
116-195 6.52e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 40.48  E-value: 6.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  116 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPND-RFYTIRYREKDKEKKWIFQICPATET--IVENLKPNTVYEF 192
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71

                   ...
gi 1770726349  193 GVK 195
Cdd:pfam00041   72 RVQ 74
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
117-195 6.70e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 40.29  E-value: 6.70e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349   117 PLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPNDRFYTIRYREKDKEKKWIFQICPA----TETIVENLKPNTVYEF 192
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTEYEF 72

                    ...
gi 1770726349   193 GVK 195
Cdd:smart00060   73 RVR 75
PRK10263 PRK10263
DNA translocase FtsK; Provisional
1078-1331 6.88e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 44.69  E-value: 6.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1078 SVTgfEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESQPVSDVLESVTLSTESPkeTIAPAKTDYV-YPTAKAPL 1156
Cdd:PRK10263   315 PIT--EPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEP--VIAPAPEGYPqQSQYAQPA 390
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1157 WP-----EEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPK-----PKTSPRPRIPQTQ 1226
Cdd:PRK10263   391 VQyneplQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQqstfaPQSTYQTEQTYQQ 470
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1227 PVPK-----VPQRVTAKPKTSPSPEVSYTTPAPKDVL----LPHKPYPEVSQSEPVLQPVTFRFEPPKTTIAPLETRGIP 1297
Cdd:PRK10263   471 PAAQeplyqQPQPVEQQPVVEPEPVVEETKPARPPLYyfeeVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVA 550
                          250       260       270
                   ....*....|....*....|....*....|....
gi 1770726349 1298 FIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP 1331
Cdd:PRK10263   551 AVPPVEAAAAVSPLASGVKKATLATGAAATVAAP 584
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1367-1646 7.50e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 44.22  E-value: 7.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1367 TTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGI 1446
Cdd:COG3401     48 TKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATT 127
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1447 ISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNS--- 1523
Cdd:COG3401    128 ATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTyyy 207
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1524 -PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQMT 1602
Cdd:COG3401    208 rVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATV 282
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1770726349 1603 NQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 1646
Cdd:COG3401    283 TTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
PRK11633 PRK11633
cell division protein DedD; Provisional
1152-1255 9.26e-04

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 42.68  E-value: 9.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1152 AKAPLWP---EEPKTEVVESITYV--SEPPETTLE-----TSPLPSQSITLPSPDEPQTEPAPKqtPRAPPKPKtsPRPR 1221
Cdd:PRK11633    39 AAIPLVPkpgDRDEPDMMPAATQAlpTQPPEGAAEavragDAAAPSLDPATVAPPNTPVEPEPA--PVEPPKPK--PVEK 114
                           90       100       110
                   ....*....|....*....|....*....|....
gi 1770726349 1222 iPQTQPVPKVPQRVTAKPKTSPSPEVSyTTPAPK 1255
Cdd:PRK11633   115 -PKPKPKPQQKVEAPPAPKPEPKPVVE-EKAAPT 146
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1545-1689 9.52e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 43.84  E-value: 9.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1545 TSPPQnPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV--ISRENGSFSGKNKSIqmtNQTFSTVENLKPNTSYEFQV 1622
Cdd:COG3401    324 LTPPA-APSGLTATAVG--SSSITLSWTASSDADVTGYNVyrSTSGGGTYTKIAETV---TTTSYTDTGLTPGTTYYYKV 397
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1770726349 1623 KPKNPLG-EGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVG 1689
Cdd:COG3401    398 TAVDAAGnESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTG 465
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
632-700 1.42e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 43.26  E-value: 1.42e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1770726349  632 PALEPATIQPEPLVPTtASKPSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTKSVSEPVP 700
Cdd:PRK14950   362 PVPAPQPAKPTAAAPS-PVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAP 429
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
650-1021 2.12e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 43.14  E-value: 2.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  650 SKPSERPKTTHRPDAPQIQPGSKPPKqllpkPQTTAEPDMPPTKSVSEPVPFETEAPSMTIVPTTDIEPVTvrTEATVTT 729
Cdd:PTZ00449   537 SKESDEPKEGGKPGETKEGEVGKKPG-----PAKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRS--AQRPTRP 609
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  730 LAPKTSQRTRTRRPRPKHKTTPRPETlqtkldfgPITPGTSSAPTTTTKRTRRPHPKPKTTPHPEV-PQTK-LVPATILE 807
Cdd:PTZ00449   610 KSPKLPELLDIPKSPKRPESPKSPKR--------PPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFdPKFKeKFYDDYLD 681
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  808 PVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVP------ATIFEPV-SPIKEAPGTTFVPVTDLEPVTFRT 880
Cdd:PTZ00449   682 AAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPklprdeEFPFEPIgDPDAEQPDDIEFFTPPEEERTFFH 761
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  881 EIPATTLATKTSKRTRPPRPRPKTTPSPQAPETKPVpatvlEPVTLRPEASTTLASKTSQRTRRPRLRTKTTPRpEAPES 960
Cdd:PTZ00449   762 ETPADTPLPDILAEEFKEEDIHAETGEPDEAMKRPD-----SPSEHEDKPPGDHPSLPKKRHRLDGLALSTTDL-ESDAG 835
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  961 KPVPTAELKPVTLR-----------------------------------TETWVTTQAPKTSQRTRRPRPKTKTTPSPEV 1005
Cdd:PTZ00449   836 RIAKDASGKIVKLKrsksfddlttveeaeemgaearkivvdddgteaddEDTHPPEEKHKSEVRRRRPPKKPSKPKKPSK 915
                          410
                   ....*....|....*.
gi 1770726349 1006 PQTKLVPSTDLEPGTL 1021
Cdd:PTZ00449   916 PKKPKKPDSAFIPSII 931
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
883-1051 2.42e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.56  E-value: 2.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  883 PATTLATKTSKRTRPPRPRPKTTPSPQAPETKPVPATVLEPVTLRPEA-----STTLASKTSQRTRRPRLRTKTTPRPEA 957
Cdd:PRK12323   374 PATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAaparrSPAPEALAAARQASARGPGGAPAPAPA 453
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  958 PESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPS-PEVPQTKLVPS-TDLEPGTLRTEAPKTMVVTTVL 1035
Cdd:PRK12323   454 PAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPwEELPPEFASPApAQPDAAPAGWVAESIPDPATAD 533
                          170
                   ....*....|....*.
gi 1770726349 1036 EPDTFRTKFPETTLAP 1051
Cdd:PRK12323   534 PDDAFETLAPAPAAAP 549
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
928-1254 3.04e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 42.25  E-value: 3.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  928 PEASTTLASKTSQRT-RRPRLRTKTTPRPEAPESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPSPEVP 1006
Cdd:pfam17823   66 APAPVTLTKGTSAAHlNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSEAFSAP 145
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1007 QTKlVPSTdlePGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPKTTS----SPEVPQNKSVSVTGF 1082
Cdd:pfam17823  146 RAA-ACRA---NASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSApatlTPARGISTAATATGH 221
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1083 EPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESQPVSDVLESVTLSTESP-KETIAPAKTDYVYPTAKAPLWPEEP 1161
Cdd:pfam17823  222 PAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPhARRLSPAKHMPSDTMARNPAAPMGA 301
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1162 KTEVVESITYVSEPPETTlETSPLPSQSITLPSPDEPQ-----------TEPAPKQTPRAPPKP--KTSPRPRI----PQ 1224
Cdd:pfam17823  302 QAQGPIIQVSTDQPVHNT-AGEPTPSPSNTTLEPNTPKsvastnlavvtTTKAQAKEPSASPVPvlHTSMIPEVeatsPT 380
                          330       340       350
                   ....*....|....*....|....*....|
gi 1770726349 1225 TQPVPKVPQRVTAKPKTSPSPEVSYTTPAP 1254
Cdd:pfam17823  381 TQPSPLLPTQGAAGPGILLAPEQVATEATA 410
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
1175-1252 3.13e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 42.46  E-value: 3.13e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1770726349 1175 PPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTP 1252
Cdd:PRK14971   391 QPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKKIPVSKVSSLGP 468
PHA03247 PHA03247
large tegument protein UL36; Provisional
257-580 3.27e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 3.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  257 DSAKSPEKAPlggvilvHLIIPGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVP 336
Cdd:PHA03247  2703 PPPPTPEPAP-------HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAP 2775
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  337 RSTKPTTSSALDVSETTLVL----SKRTPETLQTILIPQFELPLSTLAPKSLPEFPEAKTPFPFEKPRGTLASSEKP--W 410
Cdd:PHA03247  2776 AAGPPRRLTRPAVASLSESReslpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggS 2855
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  411 IVPTAKISEDSKVLQPQTatydvfsSPTTSDEPEISdsytatsdRILDSIPPKTSRTLEQPRATLAPSETPFVPQKleif 490
Cdd:PHA03247  2856 VAPGGDVRRRPPSRSPAA-------KPAAPARPPVR--------RLARPAVSRSTESFALPPDQPERPPQPQAPPP---- 2916
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  491 tsPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKperTTSAGTITPKIsksPEPTWTTPAPGKTQFISLKpkiplSPEVT 570
Cdd:PHA03247  2917 --PQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTD---PAGAGEPSGAV---PQPWLGALVPGRVAVPRFR-----VPQPA 2983
                          330
                   ....*....|
gi 1770726349  571 HTKPAPEPQT 580
Cdd:PHA03247  2984 PSREAPASST 2993
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
914-1231 3.38e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 42.37  E-value: 3.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  914 KPVPATVLEP-----VTLRPEASTTLAS----KTSQRTRRPRLRTKTT--PRPEAPESKPVPTAELKPvtlrtETWVTTQ 982
Cdd:PTZ00449   560 KPGPAKEHKPskiptLSKKPEFPKDPKHpkdpEEPKKPKRPRSAQRPTrpKSPKLPELLDIPKSPKRP-----ESPKSPK 634
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  983 APKTSQRTRRPR----PKT-KTTPSPEVPQTKLVPS------TDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAP 1051
Cdd:PTZ00449   635 RPPPPQRPSSPErpegPKIiKSPKPPKSPKPPFDPKfkekfyDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTP 714
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1052 KTQRTRRPRPRPKTTSSPEVPQNksvsvtgfEPVVHSTDaPGTTFALTELQTLILKpvtspslEMTESQPVSDVL----- 1126
Cdd:PTZ00449   715 FTTPRPLPPKLPRDEEFPFEPIG--------DPDAEQPD-DIEFFTPPEEERTFFH-------ETPADTPLPDILaeefk 778
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1127 -ESVTLSTESPKETIAPAKTDYVYPTAKAPLWPEEPK-----------------------------------TEVVESIT 1170
Cdd:PTZ00449   779 eEDIHAETGEPDEAMKRPDSPSEHEDKPPGDHPSLPKkrhrldglalsttdlesdagriakdasgkivklkrSKSFDDLT 858
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1770726349 1171 YVSEPPETTLETSPLPSQSITLPSPDEpQTEPA------------PKQTPRAPPKPKTSPRPRIPQTQPVPKV 1231
Cdd:PTZ00449   859 TVEEAEEMGAEARKIVVDDDGTEADDE-DTHPPeekhksevrrrrPPKKPSKPKKPSKPKKPKKPDSAFIPSI 930
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
1096-1306 3.43e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 3.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1096 FALTELQTLILKPVTSPSlemtESQPVSDVLESVTLSTE--SPKETIAPAKTDYVYPTAKAPLwPEEPKTEVVESITYVS 1173
Cdd:PRK12323   353 FTMTLLRMLAFRPGQSGG----GAGPATAAAAPVAQPAPaaAAPAAAAPAPAAPPAAPAAAPA-AAAAARAVAAAPARRS 427
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1174 EPPEttletsplPSQSITLPSPDEPQTEPAPkqTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPA 1253
Cdd:PRK12323   428 PAPE--------ALAAARQASARGPGGAPAP--APAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPP 497
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1770726349 1254 PKDVLLPHKPYPEVSQSEPVLQPV---------------TFRFEPPKTTIAPLETRGIPFIPMISPSP 1306
Cdd:PRK12323   498 PWEELPPEFASPAPAQPDAAPAGWvaesipdpatadpddAFETLAPAPAAAPAPRAAAATEPVVAPRP 565
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
116-195 3.50e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.63  E-value: 3.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  116 KPLQLVVGTLTPSSVFLSWgfliNPHHDWTLPSHcpndrFYTIRYREKDKE--KKWIFQICPATETIVENLKPNTVYEFG 193
Cdd:cd00063      3 PPTNLRVTDVTSTSVTLSW----TPPEDDGGPIT-----GYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFR 73

                   ..
gi 1770726349  194 VK 195
Cdd:cd00063     74 VR 75
rne PRK10811
ribonuclease E; Reviewed
1182-1356 5.82e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 41.56  E-value: 5.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1182 TSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQrVTAKPKTSPSPEVSYTTPAPKDVLLPH 1261
Cdd:PRK10811   848 VRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPV-VVAEPQPEEVVVVETTHPEVIAAPVTE 926
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1262 KPYPEVSQSEPVLQPVTFRFEP---------PKTTIAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPR 1332
Cdd:PRK10811   927 QPQVITESDVAVAQEVAEHAEPvvepqdetaDIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQV 1006
                          170       180       190
                   ....*....|....*....|....*....|.
gi 1770726349 1333 TTELAKT-------TQAPHRFYTTVRPRTSD 1356
Cdd:PRK10811  1007 PEATVEHnhatapmTRAPAPEYVPEAPRHSD 1037
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
1196-1276 6.21e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 41.47  E-value: 6.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349 1196 DEPQTEPAPKQTPRAPPKPKTSPRP-RIPQTQPVPKVPQRVTAKPKTSPSPEVSYT----TPAPKDVLLPHKPYPEVSQS 1270
Cdd:PRK14954   374 VRNDGGVAPSPAGSPDVKKKAPEPDlPQPDRHPGPAKPEAPGARPAELPSPASAPTpeqqPPVARSAPLPPSPQASAPRN 453

                   ....*.
gi 1770726349 1271 EPVLQP 1276
Cdd:PRK14954   454 VASGKP 459
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
558-1002 7.59e-03

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 41.29  E-value: 7.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  558 SLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVPKSKPALEP- 636
Cdd:pfam03154  143 STSPSIPSPQDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTq 222
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  637 ATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTksvsePVPFETEAPSMtivpttdi 716
Cdd:pfam03154  223 STAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPM-----PHSLQTGPSHM-------- 289
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  717 ePVTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETlqtkldfgpiTPGTSSAPTTTTKRTRRPHPKPKTTPHPEVP 796
Cdd:pfam03154  290 -QHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHT----------PPSQSQLQSQQPPREQPLPPAPLSMPHIKPP 358
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  797 QtklvpatilepvlrteasgTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVPATIFEPVSPIK-EAPGTTFVPVTDLEP 875
Cdd:pfam03154  359 P-------------------TTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPLSSLStHHPPSAHPPPLQLMP 419
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  876 VTFRTEIPATT--LATKTSKRTRPPRPRPKTTPSPQAPETKPVPATVLEPVTlRPEASTTLASKTSQRTRRPRLRTKTTP 953
Cdd:pfam03154  420 QSQQLPPPPAQppVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGG-PPPITPPSGPPTSTSSAMPGIQPPSSA 498
                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1770726349  954 RPEAPESKP-VPTAELKPVTLRTETWVTTQAPKT---SQRTRRPRPKTKTTPS 1002
Cdd:pfam03154  499 SVSSSGPVPaAVSCPLPPVQIKEEALDEAEEPESpppPPRSPSPEPTVVNTPS 551
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
561-787 8.21e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.01  E-value: 8.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  561 PKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRktkrpgrrprprprpKTTPSPEVPKSKPALEPATIQ 640
Cdd:PRK12323   374 PATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAAR---------------AVAAAPARRSPAPEALAAARQ 438
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726349  641 PEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTKSVSEPVPFETEAPSMTIVPTTDIEPVT 720
Cdd:PRK12323   439 ASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAP 518
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1770726349  721 VRTEAtvttlapktsqrtrtrrprpkhKTTPRPETLQTKLDFGPITPGTSSAPTTTTKRTRRPHPKP 787
Cdd:PRK12323   519 AGWVA----------------------ESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAP 563
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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