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Conserved domains on  [gi|1774222067|ref|NP_001363069|]
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tetratricopeptide repeat protein 31 isoform l [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 708416)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 108-310 1.13e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 72.33  E-value: 1.13e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 108 ARREKGLNQEPQGRGLALQKMGQEEESPPREerpQQSPKASPGLLAAalqqsqeLAKLGTSFAQNGFYHEAVVLFTQALK 187
Cdd:COG3914    71 AAALLLLAALLELAALLLQALGRYEEALALY---RRALALNPDNAEA-------LFNLGNLLLALGRLEEALAALRRALA 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 188 LNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLRggSQPDAArELR 267
Cdd:COG3914   141 LNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE--LDPDNA-DAH 217

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1774222067 268 SCLLHLTLQGQRGGICAPPLSPGALQPLPHAELAPSGLPSLRC 310
Cdd:COG3914   218 SNLLFALRQACDWEVYDRFEELLAALARGPSELSPFALLYLPD 260
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 108-310 1.13e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 72.33  E-value: 1.13e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 108 ARREKGLNQEPQGRGLALQKMGQEEESPPREerpQQSPKASPGLLAAalqqsqeLAKLGTSFAQNGFYHEAVVLFTQALK 187
Cdd:COG3914    71 AAALLLLAALLELAALLLQALGRYEEALALY---RRALALNPDNAEA-------LFNLGNLLLALGRLEEALAALRRALA 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 188 LNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLRggSQPDAArELR 267
Cdd:COG3914   141 LNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE--LDPDNA-DAH 217

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1774222067 268 SCLLHLTLQGQRGGICAPPLSPGALQPLPHAELAPSGLPSLRC 310
Cdd:COG3914   218 SNLLFALRQACDWEVYDRFEELLAALARGPSELSPFALLYLPD 260
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 178-251 2.59e-07

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 52.10  E-value: 2.59e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774222067 178 AVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQ 251
Cdd:PLN03088   21 AVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLEEYQTAKAALE 94
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 162-246 4.14e-07

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 51.91  E-value: 4.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 162 LAKLGTSFAQNGFYHEAVVLFTQALKLNPqDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 241
Cdd:TIGR00990 130 LKEKGNKAYRNKDFNKAIKLYSKAIECKP-DPVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLG 208


                  ....*
gi 1774222067 242 RFREA 246
Cdd:TIGR00990 209 KYADA 213
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 108-310 1.13e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 72.33  E-value: 1.13e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 108 ARREKGLNQEPQGRGLALQKMGQEEESPPREerpQQSPKASPGLLAAalqqsqeLAKLGTSFAQNGFYHEAVVLFTQALK 187
Cdd:COG3914    71 AAALLLLAALLELAALLLQALGRYEEALALY---RRALALNPDNAEA-------LFNLGNLLLALGRLEEALAALRRALA 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 188 LNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLRggSQPDAArELR 267
Cdd:COG3914   141 LNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE--LDPDNA-DAH 217

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1774222067 268 SCLLHLTLQGQRGGICAPPLSPGALQPLPHAELAPSGLPSLRC 310
Cdd:COG3914   218 SNLLFALRQACDWEVYDRFEELLAALARGPSELSPFALLYLPD 260
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
162-272 1.41e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 69.65  E-value: 1.41e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 162 LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 241
Cdd:COG0457    45 LYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG 124

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1774222067 242 RFREAAAVFQETLRGGSQPDAARELRSCLLH 272
Cdd:COG0457   125 RYDEAIEAYERALELDPDDADALYNLGIALE 155
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
162-273 2.93e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 68.88  E-value: 2.93e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 162 LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 241
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALG 90

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1774222067 242 RFREAAAVFQETLRGGSQ-PDAARELRSCLLHL 273
Cdd:COG0457    91 RYEEALEDYDKALELDPDdAEALYNLGLALLEL 123
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
162-268 4.53e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 68.11  E-value: 4.53e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 162 LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 241
Cdd:COG0457    79 LNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158

                          90       100
                  ....*....|....*....|....*..
gi 1774222067 242 RFREAAAVFQETLRGGSQPDAARELRS 268
Cdd:COG0457   159 RYEEALELLEKLEAAALAALLAAALGE 185
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 151-255 6.14e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 65.60  E-value: 6.14e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 151 LLAAALQQSQE----LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGW 226
Cdd:COG4783    26 LLEKALELDPDnpeaFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEH 105

                          90       100
                  ....*....|....*....|....*....
gi 1774222067 227 PRGLFRLGKALMGLQRFREAAAVFQETLR 255
Cdd:COG4783   106 PEAYLRLARAYRALGRPDEAIAALEKALE 134
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 108-255 1.33e-12

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 64.98  E-value: 1.33e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 108 ARREKGLNQEPQGRGLALQKMGQEEESPPREERPQQSPKASPGLLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALK 187
Cdd:COG5010     3 ALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQ 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1774222067 188 LNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLR 255
Cdd:COG5010    83 LDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
153-275 5.77e-12

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 64.55  E-value: 5.77e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 153 AAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFR 232
Cdd:COG4785    67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1774222067 233 LGKALMGLQRFREAAAVFQETLRgGSQPDAARELRSCLLHLTL 275
Cdd:COG4785   147 RGIALYYLGRYELAIADLEKALE-LDPNDPERALWLYLAERKL 188
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 106-255 1.71e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.40  E-value: 1.71e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 106 LSARREKGLNQEPQGRGLALQKMGQEEESPPREERPQQSPKASPGLLAAALQQSQELAKLGTSFAQ----NGFYHEAVVL 181
Cdd:COG3914    21 AAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALllqaLGRYEEALAL 100

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774222067 182 FTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLR 255
Cdd:COG3914   101 YRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALE 174
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 157-273 1.42e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 58.66  E-value: 1.42e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 157 QQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKA 236
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1774222067 237 LMGLQRFREAAAVFQETLR-GGSQPDAARELRSCLLHL 273
Cdd:COG4783    82 LLKAGDYDEALALLEKALKlDPEHPEAYLRLARAYRAL 119
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 152-268 1.48e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 58.48  E-value: 1.48e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 152 LAAALQQSQE----LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWP 227
Cdd:COG4235     6 LRQALAANPNdaegWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1774222067 228 RGLFRLGKALMGLQRFREAAAVFQETLRGGSQPDAARELRS 268
Cdd:COG4235    86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEA 126
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
169-264 1.44e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 54.41  E-value: 1.44e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 169 FAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALAdAQVALTLRPGWPRGLFRLGKALMGLQRFREAAA 248
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                          90
                  ....*....|....*.
gi 1774222067 249 VFQETLRggSQPDAAR 264
Cdd:COG3063    81 YLERALE--LDPSALR 94
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
186-255 1.39e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 55.01  E-value: 1.39e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 186 LKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLR 255
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALE 70
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 151-273 2.16e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 51.65  E-value: 2.16e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 151 LLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGL 230
Cdd:COG2956   136 LLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPAL 215

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1774222067 231 FRLGKALMGLQRFREAAAVFQETLRGGSQPDAARELRSCLLHL 273
Cdd:COG2956   216 PRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERK 258
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 178-251 2.59e-07

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 52.10  E-value: 2.59e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774222067 178 AVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQ 251
Cdd:PLN03088   21 AVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLEEYQTAKAALE 94
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 162-246 4.14e-07

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 51.91  E-value: 4.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 162 LAKLGTSFAQNGFYHEAVVLFTQALKLNPqDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 241
Cdd:TIGR00990 130 LKEKGNKAYRNKDFNKAIKLYSKAIECKP-DPVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLG 208


                  ....*
gi 1774222067 242 RFREA 246
Cdd:TIGR00990 209 KYADA 213
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 151-273 4.57e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.88  E-value: 4.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 151 LLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGL 230
Cdd:COG2956   102 LLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARAL 181

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1774222067 231 FRLGKALMGLQRFREAAAVFQETLRggSQPD---AARELRSCLLHL 273
Cdd:COG2956   182 LLLAELYLEQGDYEEAIAALERALE--QDPDylpALPRLAELYEKL 225
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 177-255 1.19e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.31  E-value: 1.19e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1774222067 177 EAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLR 255
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALA 79
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 151-264 1.72e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.96  E-value: 1.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 151 LLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGL 230
Cdd:COG2956    68 LLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAY 147

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1774222067 231 FRLGKALMGLQRFREAAAVFQETLRggSQPDAAR 264
Cdd:COG2956   148 CELAELYLEQGDYDEAIEALEKALK--LDPDCAR 179
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 165-224 5.12e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.03  E-value: 5.12e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 165 LGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRP 224
Cdd:COG5010    94 LALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 151-271 8.08e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.95  E-value: 8.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 151 LLAAALQQSQELAKlGTSFAQNGFYHEAVVLFTQALKLNPQD---HRLFGNrsfCHERLGQPAWALADAQVALTLRPGWP 227
Cdd:COG2956     1 LLLPVAAALGWYFK-GLNYLLNGQPDKAIDLLEEALELDPETveaHLALGN---LYRRRGEYDRAIRIHQKLLERDPDRA 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1774222067 228 RGLFRLGKALMGLQRFREAAAVFQETLR-GGSQPDAARELRSCLL 271
Cdd:COG2956    77 EALLELAQDYLKAGLLDRAEELLEKLLElDPDDAEALRLLAEIYE 121
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 162-224 1.20e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 41.72  E-value: 1.20e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1774222067 162 LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRP 224
Cdd:COG4783    75 RLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 168-265 1.80e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.75  E-value: 1.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 168 SFAQNGFYHEAVVLFTQALKLNPqDHRLFGNRSF----CHERLGQPAWALADAQVALTLRPGW---PRGLFRLGKALMGL 240
Cdd:COG1729     2 ALLKAGDYDEAIAAFKAFLKRYP-NSPLAPDALYwlgeAYYALGDYDEAAEAFEKLLKRYPDSpkaPDALLKLGLSYLEL 80

                          90       100
                  ....*....|....*....|....*
gi 1774222067 241 QRFREAAAVFQETLRGGSQPDAARE 265
Cdd:COG1729    81 GDYDKARATLEELIKKYPDSEAAKE 105
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 151-266 3.03e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.02  E-value: 3.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 151 LLAAALQQSQELA----KLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGW 226
Cdd:COG2956    30 LLEEALELDPETVeahlALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDD 109

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1774222067 227 PRGLFRLGKALMGLQRFREAAAVFQETLR-GGSQPDAAREL 266
Cdd:COG2956   110 AEALRLLAEIYEQEGDWEKAIEVLERLLKlGPENAHAYCEL 150
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
162-293 3.81e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.53  E-value: 3.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222067 162 LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLfRLGKALMGLQ 241
Cdd:COG0457   113 LYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAA-ALGEAALALA 191

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1774222067 242 RFREAAAVFQETLRGGSQPDAARELRSCLLHLTLQGQRGGICAPPLSPGALQ 293
Cdd:COG0457   192 AAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQY 243
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
202-255 6.38e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.61  E-value: 6.38e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1774222067 202 CHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAvFQETLR 255
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALK 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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