|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02882 |
PLN02882 |
aminoacyl-tRNA ligase |
6-1039 |
0e+00 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215477 [Multi-domain] Cd Length: 1159 Bit Score: 1570.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 6 PENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGW 85
Cdd:PLN02882 5 GKDFSFPKQEEKILSLWSEIDAFKTQLKRTEGLPEYIFYDGPPFATGLPHYGHILAGTIKDIVTRYQSMTGHHVTRRFGW 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 86 DCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQ 165
Cdd:PLN02882 85 DCHGLPVEYEIDKKLGIKRRDDVLKMGIDKYNEECRSIVTRYSKEWEKTVTRTGRWIDFENDYKTMDPKFMESVWWVFKQ 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 166 LYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVFVTFPL-EEDETVSLVAWTTTPWTLPSNLAVCVNPEMQY 244
Cdd:PLN02882 165 LFEKGLVYKGFKVMPYSTACKTPLSNFEAGLNYKDVSDPAVMVSFPIvGDPDNASFVAWTTTPWTLPSNLALCVNPNFTY 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 245 VKIKDVARGRLLILMEARLSALY-------------KLESDYEILERFPGAYLKGKKYRPLFDYFLKCKENgAFTVLVDN 311
Cdd:PLN02882 245 VKVRNKYTGKVYIVAESRLSALPtakpkskkgskpeNAAEGYEVLAKVPGSSLVGKKYEPLFDYFSEFSDT-AFRVVADD 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 312 YVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTTEVTDFAGQYVKDADKSIIRTLKEQGRLLVAT 391
Cdd:PLN02882 324 YVTDDSGTGVVHCAPAFGEDDYRVCLANGIIEKGGNLPVPVDDDGCFTEKVTDFSGRYVKDADKDIIAAIKAKGRLVKSG 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 392 TFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWV 471
Cdd:PLN02882 404 SITHSYPFCWRSDTPLIYRAVPSWFVKVEEIKDRLLENNKQTYWVPDYVKEKRFHNWLENARDWAVSRSRFWGTPLPIWI 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 472 SDDFEEVVCIGSVAELEELSGAKISDLHRESVDHLTIPSRCGK--GSLHRISEVFDCWFESGSMPYAQVHYPFENKREFE 549
Cdd:PLN02882 484 SDDGEEVVVIGSIAELEKLSGVKVTDLHRHFIDHITIPSSRGPefGVLRRVDDVFDCWFESGSMPYAYIHYPFENKELFE 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 550 DAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLIN 629
Cdd:PLN02882 564 KNFPADFVAEGLDQTRGWFYTLMVLSTALFDKPAFKNLICNGLVLAEDGKKMSKSLKNYPDPNEVIDKYGADALRLYLIN 643
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 630 SPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRFLIQNVLRLQKEEEIEFL-YNENTVRESPNITDRWILSFMQSLIGFFE 708
Cdd:PLN02882 644 SPVVRAEPLRFKEEGVFGVVKDVFLPWYNAYRFLVQNAKRLEVEGGAPFVpLDLAKLQNSANVLDRWINSATQSLVKFVR 723
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 709 TEM--------------------------------GENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNL-KVL 755
Cdd:PLN02882 724 EEMgayrlytvvpylvkfidnltniyvrfnrkrlkGRTGEEDCRTALSTLYNVLLTSCKVMAPFTPFFTEVLYQNLrKVL 803
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 756 idPVSVQdkdtlSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALKDIK-SL 834
Cdd:PLN02882 804 --PGSEE-----SIHYCSFPQVDEGELDERIEQSVSRMQTVIELARNIRERHNKPLKTPLKEMVVVHPDAEFLDDITgKL 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 835 EKYIIEELNVRKVTLSTDKNKYgIRLRAEPDHMVLGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIR 914
Cdd:PLN02882 877 KEYVLEELNVRSLVPCNDPLKY-ASLRAEPNFSVLGKRLGKSMGLVAKEVKAMSQDDILEFEKAGEVTIAGHTLKAGDIK 955
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 915 LMYTFDQATG-GTAQFEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYK--AKSEGTYLN 991
Cdd:PLN02882 956 VVRDFKRPEGvSKEDIDAAGDGDVLVILDLRVDESLLEAGVAREVVNRIQKLRKKAGLEPTDKVEVFFEslDEVDESALS 1035
|
1050 1060 1070 1080 1090
....*....|....*....|....*....|....*....|....*....|
gi 1811715223 992 SVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEKTQLKGSELE--ITLTR 1039
Cdd:PLN02882 1036 QVLKSQAQYIRESLGSPLLPSSMMPSHAVVIAEESFHGVSGLSfkISLAR 1085
|
|
| PTZ00427 |
PTZ00427 |
isoleucine-tRNA ligase, putative; Provisional |
5-971 |
0e+00 |
|
isoleucine-tRNA ligase, putative; Provisional
Pssm-ID: 173617 [Multi-domain] Cd Length: 1205 Bit Score: 1080.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 5 VPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFG 84
Cdd:PTZ00427 68 VSENPNIVEEEEKVLKYWKSIDAFNTSNKLAKNKKAYIFYDGPPFATGLPHYGHLLAGIIKDCVTRYFYQCGFSVERKFG 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 85 WDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFK 164
Cdd:PTZ00427 148 WDCHGLPIEYEIEKENNINKKEDILKMGIDVYNEKCRGIVLKYSNEWVKTVERIGRWIDFKNDYKTMDKTFMESVWWVFS 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 165 QLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVFVTF-------------PLEEDETV------------- 218
Cdd:PTZ00427 228 ELYKNNYVYKSFKVMPYSCKCNTPISNFELNLNYKDTPDPSIIISFvlcsdfpkveeecNIEEDKQLlgekysvlynnkr 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 219 --------------------SLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEARLSALYK-LESDYE--- 274
Cdd:PTZ00427 308 ensnngnnnstnnvcyaqhsEILAWTTTPWTLPSNLALCVNEHFTYLRIHHVKSNRVVIVGECRLEWIMKeLKWNVEdlk 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 275 ILERFPGAYLKGKKYRPLFDYFLKcKEN---GAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDS-LPVC 350
Cdd:PTZ00427 388 IVNRFKGKELKGLRYKPLFTNFYE-KYNfkeRAYKILADDFVTDDAGTGIVHCAPTYGEDDFRVCKKNGVIDPEKnIFID 466
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 351 PVDASGCFTTEVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNN 430
Cdd:PTZ00427 467 PLDANGYFTNEVEEVQNLYIKEADNVIKKKLKNENRLLSNNTIVHSYPFCWRSDTPLIYRAIPAWFIRVSNSTNELVKNN 546
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 431 DLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELEELSGAK-ISDLHRESVDHLTIP 509
Cdd:PTZ00427 547 ETTYWIPAHIKEKKFHNWIKDAKDWCISRNRYWGTPIPIWADEKMETVICVESIKHLEELSGVKnINDLHRHFIDHIEIK 626
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 510 SRCGKG--SLHRISEVFDCWFESGSMPYAQVHYPFENKRE-FEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKN 586
Cdd:PTZ00427 627 NPKGKTypKLKRIPEVFDCWFESGSMPYAKVHYPFSTEKEdFHKIFPADFIAEGLDQTRGWFYTLLVISTLLFDKAPFKN 706
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 587 VIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRFLIQN 666
Cdd:PTZ00427 707 LICNGLVLASDGKKMSKRLKNYPDPLYILDKYGADSLRLYLINSVAVRAENLKFQEKGVNEVVKSFILPFYHSFRFFSQE 786
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 667 VLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEM--------------------------------GEN 714
Cdd:PTZ00427 787 VTRYECLNKKQFLFNTDYIYKNDNIMDQWIFSSVQSLTKSVHTEMkayklynvlpkllqfienltnwyirlnrdrmrGSL 866
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 715 GMEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLK-VLIDPVSVQDKDT--------------LSIHYLMLPRVRE 779
Cdd:PTZ00427 867 GEENCLQSLCTTYRTLHLFTVLMAPFTPFITEYIYQQLRrVKSTNEHNENNETgntkegdlnrgvihKSVHFIMLPQVDE 946
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 780 E-LIDKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNkyGI 858
Cdd:PTZ00427 947 KyIIDYEIIELIEKMKDVILLGRVLRERRKVASKKPLKSITILHPNESYFKNFDQISNYIKEELNVLNVECSNDTS--CL 1024
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 859 RLRAEPDHMVLGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDI--RLMYTF-DQATggtaqfEAHSDA 935
Cdd:PTZ00427 1025 DFSAIPNYKTLGVKLGYNLKKVQNKIKNMDSESIKLYQQEGKITLDNVTLEGDDIiiQMKPNFqNDNT------DIISNN 1098
|
1050 1060 1070
....*....|....*....|....*....|....*.
gi 1811715223 936 QALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNL 971
Cdd:PTZ00427 1099 YVTILMDFTTDQQLENMASARELCNHIQKMRKNLSL 1134
|
|
| IleS |
COG0060 |
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA ... |
6-965 |
0e+00 |
|
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439830 [Multi-domain] Cd Length: 931 Bit Score: 991.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 6 PENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGW 85
Cdd:COG0060 13 PMRANLPKREPEILKFWEENDIYEKSREARAGRPKFVLHDGPPYANGDIHIGHALNKILKDIIVRYKTMRGFDVPYVPGW 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 86 DCHGLPVEYEIDKTLGIRGPeDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQ 165
Cdd:COG0060 93 DCHGLPIELKVEKELGIKKK-DIEKVGIAEFREKCREYALKYVDEQREDFKRLGVWGDWDNPYLTMDPEYEESIWWALKK 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 166 LYDKGLVYRGVKVMPFSTACNTPLSNFEShqNYKDVQDPSVFVTFPLEED------ETVSLVAWTTTPWTLPSNLAVCVN 239
Cdd:COG0060 172 LYEKGLLYKGLKPVPWCPRCGTALAEAEV--EYKDVTSPSIYVKFPVKDEkallllEDAYLVIWTTTPWTLPANLAVAVH 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 240 PEMQYVKIKdVARGRLLILMEARLSAL---YKLEsDYEILERFPGAYLKGKKYRPLFDYFLKckENGAFTVLVDNYVKEE 316
Cdd:COG0060 250 PDIDYVLVE-VTGGERLILAEALVEAVlkeLGIE-DYEVLATFKGAELEGLRYEHPFYYVVG--YDRAHPVILGDYVTTE 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 317 EGTGVVHQAPYFGAEDYRVCMDFNiirkdsLPV-CPVDASGCFTTEVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTH 395
Cdd:COG0060 326 DGTGIVHTAPGHGEDDFEVGKKYG------LPVlNPVDDDGRFTEEAPLFAGLFVKDANPAIIEDLKERGALLAREKITH 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 396 SYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDLCYWVPElVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDF 475
Cdd:COG0060 400 SYPHCWRCKTPLIYRATPQWFISMDKLRDRALEAIEKVNWIPE-WGEGRFGNMLENRPDWCISRQRYWGVPIPIWVCEDC 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 476 EEVV----CIGSVAELEELSGAKIS---DLHRESVDHlTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVhypfENKREF 548
Cdd:COG0060 479 GELHrteeVIGSVAELLEEEGADAWfelDLHRPFLDE-TLKCPKCGGTMRRVPDVLDVWFDSGSMHFAVL----ENREEL 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 549 edAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLI 628
Cdd:COG0060 554 --HFPADFYLEGSDQTRGWFYSSLLTSTALFGRAPYKNVLTHGFVLDEDGRKMSKSLGNVVDPQEVIDKYGADILRLWVA 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 629 NSPvvRAENLRFKEEGVRDVlKDVLLPWYNAYRFLIQNvlrLQKeeeieFLYNENTVR-ESPNITDRWILSFMQSLIgff 707
Cdd:COG0060 632 SSD--YWGDLRFSDEILKEV-RDVYRRLRNTYRFLLAN---LDD-----FDPAEDAVPyEDLPELDRWILSRLNELI--- 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 708 eTEMgENGMED-------------CVM--------------------------ALETLFSVLLSLCRLMAPYTPFLTELM 748
Cdd:COG0060 698 -KEV-TEAYDNydfhrayralhnfCVEdlsnwyldiskdrlyteaadsldrraAQTTLYEVLETLVRLLAPILPFTAEEI 775
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 749 YQNLKvlidpvsvqDKDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGR----VIRDRKTipIKYPLKEIVVIHQD 824
Cdd:COG0060 776 WQNLP---------GEAEESVHLADWPEVDEELIDEELEAKWDLVREVRSAVLkaleAARKEKL--IRQPLEAAVVLYAD 844
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 825 PEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGirlraepdhmvlgkrlKGAFKAvmtsikqlsseeLEQFQKTGTIVVE 904
Cdd:COG0060 845 EELAAALESLGDLLAEELNVSEVELVDDAEDLG----------------KDALKA------------LDVEGISVTVEVE 896
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1811715223 905 ghelhdedirlmytfdQATGGTAQFEAHsdaqalVLLDVTPDQsmvdEGMAREVINRIQKL 965
Cdd:COG0060 897 ----------------KADGEKCERCWH------YEVGWTPEH----EGLCRRCVRRVQGL 931
|
|
| tRNA-synt_1 |
pfam00133 |
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too ... |
17-639 |
0e+00 |
|
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too dissimilar to be included.
Pssm-ID: 459685 [Multi-domain] Cd Length: 602 Bit Score: 974.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 17 KILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEI 96
Cdd:pfam00133 1 QIYEFWDEQGYFKPELEKRKGKPSFTIHDGPPNATGSLHIGHALAKTLKDIVIRYKRMKGYYVLWVPGWDHHGLPTEQVV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 97 DKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGV 176
Cdd:pfam00133 81 EKKLGIKEKKTRHKYGREEFREKCREWKMEYADEIRKQFRRLGRSIDWDREYFTMDPELEAAVWEVFVRLHDKGLIYRGK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 177 KVMPFSTACNTPLSNFEShqNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKikdvaRGRLL 256
Cdd:pfam00133 161 KLVNWSPALNTALSNLEV--EYKDVKGPSIHVAFPLADDEGASLVIWTTTPWTLPGNTAVAVNPEFDYVI-----TGEGY 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 257 ILMEARLSALYKLESDYEILERFPGAYLKGKKYRPLFdyflkckENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVC 336
Cdd:pfam00133 234 ILAEALLKSLYKKGTDKKILEDFRGKELEGKEAIHPF-------VNREIPIITDDYVDMEFGTGAVHIAPAHGENDYEVG 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 337 MDFNIirkdsLPVCPVDASGCFTTEVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWF 416
Cdd:pfam00133 307 QRHNL-----EVINPVDDDGTFTEEAPDFQGVYRFDARKKIVELLTEKGLLLKIEPFTHSYPFCWRSGTPIIPRATPQWF 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 417 VRVENMVDQLLRNNDLCYWVPELvREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELEEL---SGA 493
Cdd:pfam00133 382 VRMDELADQALEAVEKVQFVPKS-GEKRYFNWLANIQDWCISRQRWWGHPIPAWVSKDTEEVVCRGELFELVAGrfeEEG 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 494 KISDLHRESVDHLtipsRCGKGSLHRISEVFDCWFESGSMPYAQVHYPFENKREFEDAFPADFIAEGIDQTRGWFYTLLV 573
Cdd:pfam00133 461 SIKWLHREAKDKL----GYGKGTLEQDEDVLDTWFSSGSWPFSTLGWPFVNTEEFKKFFPADMLLEGSDQTRGWFYRMIM 536
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1811715223 574 LATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLR 639
Cdd:pfam00133 537 LSTALTGSVPFKNVLVHGLVRDEQGRKMSKSLGNVIDPLDVIDKYGADALRLWLANSDYGRDINLS 602
|
|
| ileS |
TIGR00392 |
isoleucyl-tRNA synthetase; The isoleucyl tRNA synthetase (IleS) is a class I amino acyl-tRNA ... |
5-832 |
0e+00 |
|
isoleucyl-tRNA synthetase; The isoleucyl tRNA synthetase (IleS) is a class I amino acyl-tRNA ligase and is particularly closely related to the valyl tRNA synthetase. This model may recognize IleS from every species, including eukaryotic cytosolic and mitochondrial forms. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273054 [Multi-domain] Cd Length: 861 Bit Score: 938.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 5 VPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFG 84
Cdd:TIGR00392 2 FPMRGNLSKREEKILAFWQENDIFEKVKKLNKGKPEFIFHDGPPYANGSIHLGHALNKILKDIILRYKTMQGFNVTRKPG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 85 WDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFK 164
Cdd:TIGR00392 82 WDTHGLPIEHKVEKKLGISGKKEISSLEIEEFREKCREFALKQIEEQREQFQRLGVWGDWENPYKTMDPSYEESQWWLFK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 165 QLYDKGLVYRGVKVMPFSTACNTPLSNFESHQ--NYKDVQDPSVFVTFPLEEDE-------TVSLVAWTTTPWTLPSNLA 235
Cdd:TIGR00392 162 EAHEKGLLYRGLKPVYWSPRCRTALAEAEVEYkeNYKDVKDPSIYVKFPVKKDKktylkvkLSSLLIWTTTPWTLPSNLA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 236 VCVNPEMQYVKIKDVARGRLLILMEARLSALY-KLESDYEILERFPGAYLKGKKYRPLFDYFLKCKENGAFTVLVDNYVK 314
Cdd:TIGR00392 242 IAVHPDFEYALVQDNTKVEYFILAKKLVEKLYnKAGSDYEIIKTFKGSDLEGLEYEHPLYDFVSQLKEGAPVVIGGDHVT 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 315 EEEGTGVVHQAPYFGAEDYRVCmdfniiRKDSLPV-CPVDASGCFTTEVTDFAGQYVKDADKSIIRT-------LKEQGR 386
Cdd:TIGR00392 322 TEDGTGIVHTAPGHGEEDYEIG------KKYGLEVlSPVDEKGVYTEGVNDFQGRFVKDADKDIIKAnkiiieqLKDKGL 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 387 LLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDLCYWVPELVrEKRFGNWLKDARDWTISRNRYWGTP 466
Cdd:TIGR00392 396 LLKAEKITHSYPHCWRTKTPVIYRATEQWFIKTKDIKDQMLEQIKKVNWVPEWG-EGRFGNWLENRPDWCISRQRYWGIP 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 467 IPLWVSDDFEEVVCIGSVAELEEL-----SGAKISDLHRESVDHLTIPSRCGkGSLHRISEVFDCWFESGSMPYAQVHYP 541
Cdd:TIGR00392 475 IPIWYCEDTGEPIVVGSIEELIELielkgIDAWFEDLHRDFLDKITLKSGDG-GEYRRVPDVLDVWFDSGSMPYASIHYP 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 542 FENKrEFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGAD 621
Cdd:TIGR00392 554 FENE-KFKEVFPADFILEGSDQTRGWFYSSLAIGTALFGQAPYKNVITHGFTLDEKGRKMSKSLGNVVDPLKVINKYGAD 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 622 ALRLYLINSpvVRAENLRFKEEGVRDVLKDVLLPWYNAYRFLIQ--NVLRLQKEEEIEFLYNENTVrespnitDRWILSF 699
Cdd:TIGR00392 633 ILRLYVASS--DPWEDLRFSDEILKQVVEKYRKIRWNTYRFLLTyaNLDKFDPLFNSVAVEKFPEE-------DRWILSR 703
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 700 MQSLI--------------------GFFETEM-------------GENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTE 746
Cdd:TIGR00392 704 LNSLVeevnealekynfhkvlralqDFIVEELsnwyiriirdrlyCEAKDNDKRAAQTTLYYALLTLVRLLAPFLPHTAE 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 747 LMYQNLKvlidpvsvQDKDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPE 826
Cdd:TIGR00392 784 EIYQNLP--------GGEEEESVHLNLWPEVDEEFIDEALEANMAIVREIVEAFLALRDAANKKLRQPLKELVIGKSLEA 855
|
....*.
gi 1811715223 827 ALKDIK 832
Cdd:TIGR00392 856 VLKAVE 861
|
|
| IleRS_core |
cd00818 |
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases ... |
39-640 |
1.60e-158 |
|
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases (IleRS) catalytic core domain . This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. IleRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173909 [Multi-domain] Cd Length: 338 Bit Score: 476.72 E-value: 1.60e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 39 PKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNN 118
Cdd:cd00818 1 PEFVFHDGPPYANGLPHYGHALNKILKDIINRYKTMQGYYVPRRPGWDCHGLPIELKVEKELGISGKKDIEKMGIAEFNA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 119 QCRAIVMRYSAEWKSTVSRLGRWIDFDNDyktlypqfmesvwwvfkqlydkglvyrgvkvmpfstacntplsnfeshqnY 198
Cdd:cd00818 81 KCREFALRYVDEQEEQFQRLGVWVDWENP--------------------------------------------------Y 110
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 199 KdvqdpsvfvtfpleedetvslvawTTTPWTlpsnlavcvnpemqyvkikdvargrllilMEARLSALYKLesdyeiler 278
Cdd:cd00818 111 K------------------------TMDPEY-----------------------------MESVWWVFKQL--------- 128
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 279 fpgaYLKGKKYRplfdyflkckengaftvlvdnyvkeeegtgvvhqapyfgaeDYRVCMdfniirkdslpvcpvdasgcf 358
Cdd:cd00818 129 ----HEKGLLYR-----------------------------------------GYKVVP--------------------- 142
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 359 ttevtdfagqyvkdadksiirtlkeqgrllvattfthsypfcWrsdtPLIYKAVPSWFVRVENMVDQLLRNNDLCYWVPE 438
Cdd:cd00818 143 ------------------------------------------W----PLIYRATPQWFIRVTKIKDRLLEANDKVNWIPE 176
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 439 LVREkRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCigsvaeleelsgakisdlhresvdhltipsrcgkgslH 518
Cdd:cd00818 177 WVKN-RFGNWLENRRDWCISRQRYWGTPIPVWYCEDCGEVLV-------------------------------------R 218
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 519 RISEVFDCWFESGSMPYAQVHYPFENKrEFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDG 598
Cdd:cd00818 219 RVPDVLDVWFDSGSMPYAQLHYPFENE-DFEELFPADFILEGSDQTRGWFYSLLLLSTALFGKAPYKNVIVHGFVLDEDG 297
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 1811715223 599 QKMSKRKKNYPDPVSIIQKYGADALRLYLINSPvVRAENLRF 640
Cdd:cd00818 298 RKMSKSLGNYVDPQEVVDKYGADALRLWVASSD-VYAEDLRF 338
|
|
| valS |
TIGR00422 |
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase ... |
6-905 |
8.49e-118 |
|
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase and is particularly closely related to the isoleucyl tRNA synthetase. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273070 [Multi-domain] Cd Length: 861 Bit Score: 387.11 E-value: 8.49e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 6 PENINFPAEEEKILEFWTEFNCFQecLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGW 85
Cdd:TIGR00422 2 PKDYDPHEVEKKWYKKWEKSGFFK--PDGNSNKPPFCIDIPPPNVTGSLHIGHALNWSIQDIIARYKRMKGYNVLWLPGT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 86 DCHGLPVEYEIDKTLGIRGPE--DVakmGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVF 163
Cdd:TIGR00422 80 DHAGIATQVKVEKKLGAEGKTkhDL---GREEFREKIWEWKEESGGTIKNQIKRLGASLDWSRERFTMDEGLSKAVKEAF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 164 KQLYDKGLVYRGVKVMPFSTACNTPLSNFEShqNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEmq 243
Cdd:TIGR00422 157 VRLYEKGLIYRGEYLVNWDPKLNTAISDIEV--EYKEVKGKLYYIRYPLANGSKDYLVVATTRPETMFGDTAVAVHPE-- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 244 yvkikdvargrllilmearlsalyklesDyeilERFpgAYLKGKKYR-PLFDYFLKckengaftVLVDNYVKEEEGTGVV 322
Cdd:TIGR00422 233 ----------------------------D----ERY--KHLIGKKVIlPLTGRKIP--------IIADEYVDMEFGTGAV 270
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 323 HQAPyfgAEDYRvcmDFNIIRKDSLP-VCPVDASGCFTTEVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCW 401
Cdd:TIGR00422 271 KVTP---AHDFN---DYEWGKRHNLEfINILDEDGLLNENAGKYQGLTRFEARKKIVEDLKEEGLLVKIEPHTHNVGTCW 344
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 402 RSDTPLIYKAVPSWFVRVENMVDQLLR--NNDLCYWVPELVrEKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVV 479
Cdd:TIGR00422 345 RSGTVVEPLLSKQWFVKVEKLADKALEaaEEGEIKFVPKRM-EKRYLNWLRNIKDWCISRQLIWGHRIPVWYCKECGEVY 423
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 480 cigsVAELEELSGAKISDlhresvdhltipsrCGKGSLHRISEVFDCWFESGSMPYAQVHYPfENKREFEDAFPADFIAE 559
Cdd:TIGR00422 424 ----VAKEEPLPDDKTNT--------------GPSVELEQDTDVLDTWFSSSLWPFSTLGWP-DETKDLKKFYPTDLLVT 484
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 560 GIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLINSpVVRAENLR 639
Cdd:TIGR00422 485 GYDIIFFWVARMIFRSLALTGQVPFKEVYIHGLVRDEQGRKMSKSLGNVIDPLDVIEKYGADALRFTLASL-VTPGDDIN 563
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 640 FKE---EGVRDVLKDVllpwYNAYRFLIQNVlrlqkEEEIEFLYNENTVRESpnitDRWILSFMQSLIGFFETEMGENGM 716
Cdd:TIGR00422 564 FDWkrvESARNFLNKL----WNASRFVLMNL-----SDDLELSGGEEKLSLA----DRWILSKLNRTIKEVRKALDKYRF 630
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 717 EDCV--------------------------------MALETLFSVLLSLCRLMAPYTPFLTELMYQNLKvlidpvsvqdK 764
Cdd:TIGR00422 631 AEAAkalyefiwndfcdwyielvkyrlyngneaekkAARDTLYYVLDKALRLLHPFMPFITEEIWQHFK----------E 700
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 765 DTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKeIVVIHQDPEALKDIKSLEKYIIEELNV 844
Cdd:TIGR00422 701 GADSIMLQSYPVVDAEFVDEEAEKAFELLKEIIVSIRNLKAESNIPPNAPLK-VLLIYTEAETAERLKLNAVDIKGAINF 779
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1811715223 845 RKVTLSTDKNKYGIRL-RAEPDHMVLG--KRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEG 905
Cdd:TIGR00422 780 SEVEVVIEKPEVTEAVvELVPGFEIIIpvKGLINKAKELARLQKQLDKEKKEVIRIEGKLENEG 843
|
|
| valS |
PRK13208 |
valyl-tRNA synthetase; Reviewed |
1-853 |
2.82e-99 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 237306 [Multi-domain] Cd Length: 800 Bit Score: 334.85 E-value: 2.82e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 1 MLQQVPENINFPAEEEKILEFWTEFNCFQEclKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVD 80
Cdd:PRK13208 2 MMPELPKKYDPEELEEKWQKIWEEEGTYKF--DPDERKPVYSIDTPPPTVSGSLHIGHVFSYTHTDFIARYQRMRGYNVF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 81 RRFGWDCHGLPVEYEIDKTLGIRgPEDVAKmgiTEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTlypqfMESVW 160
Cdd:PRK13208 80 FPQGWDDNGLPTERKVEKYYGIR-KDDISR---EEFIELCRELTDEDEKKFRELWRRLGLSVDWSLEYQT-----ISPEY 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 161 WV-----FKQLYDKGLVYRGVKVMPFSTACNTPLSNFEshQNYKDVQDPSVFVTFPLEEDETVsLVAwTTTPWTLPSNLA 235
Cdd:PRK13208 151 RRisqksFLDLYKKGLIYRAEAPVLWCPRCETAIAQAE--VEYREREGKLNYIKFPVEDGEEI-EIA-TTRPELLPACVA 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 236 VCVNPEmqyvkikdvargrllilmearlsalyklesDyeilERFpgAYLKGKKYR-PLFDYFLKckengaftVLVDNYVK 314
Cdd:PRK13208 227 VVVHPD------------------------------D----ERY--KHLVGKTAIvPLFGVEVP--------ILADPLVD 262
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 315 EEEGTGVVHqapyfgaedyrVC-----MDFNIIRKDSLPVCPV-DASGCFTTEVTDFAGQYVKDADKSIIRTLKEQGRLL 388
Cdd:PRK13208 263 PDFGTGAVM-----------ICtfgdkTDVTWWRELNLPTRIIiDEDGRMTEAAGKLAGLTIEEARKKIVEDLKSGGLLG 331
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 389 VATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDLCYWVPELVReKRFGNWLKD-ARDWTISRNRYWGTPI 467
Cdd:PRK13208 332 KQEPIKHNVKFCERCDTPLEILVTRQWFIKVLDLKEELLERGKEINWYPEHMR-VRLENWIEGlNWDWCISRQRYFGTPI 410
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 468 PLWVSDDFEEVVcigsVAELEELSgakisdlhresVDhltiPSR----------CGKGSLHRISEVFDCWFESGSMPYAQ 537
Cdd:PRK13208 411 PVWYCKDCGHPI----LPDEEDLP-----------VD----PTKdeppgykcpqCGSPGFEGETDVMDTWATSSITPLIV 471
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 538 VHYPfENKREFEDAFPADFIAEGIDQTRGW-FYTLLvLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQ 616
Cdd:PRK13208 472 TGWE-RDEDLFEKVFPMDLRPQGHDIIRTWlFYTIL-RAYLLTGKLPWKNIMISGMVLDPDGKKMSKSKGNVVTPEELLE 549
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 617 KYGADALRLYLINSPVvrAENLRFKEEGV----RDVLKdvLLpwyNAYRFliqnVLRLQKEEEIEFLYNENTVrespnit 692
Cdd:PRK13208 550 KYGADAVRYWAASARL--GSDTPFDEKQVkigrRLLTK--LW---NASRF----VLHFSADPEPDKAEVLEPL------- 611
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 693 DRWILSFMQSLI--------------------GFFET-------EM------GENGMEDCVMALETLFSVLLSLCRLMAP 739
Cdd:PRK13208 612 DRWILAKLAKVVekatealenydfakaleeieSFFWHvfcddylELvksrayGEDEEEEQKSARYTLYTVLDTLLRLLAP 691
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 740 YTPFLTELMYQNLKvlidpvsvqdkdTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKEIV 819
Cdd:PRK13208 692 FLPFITEEVWSWLY------------GGSVHRASWPEPDEELIDEEDEELGELAKEILSAVRKYKSEAGLSLNAPLKKVE 759
|
890 900 910
....*....|....*....|....*....|....
gi 1811715223 820 VIhqDPEALKDIKSLEKYIIEELNVRKVTLSTDK 853
Cdd:PRK13208 760 VY--GPADLELLEAAEEDLKAAGNIEELELVEGD 791
|
|
| PLN02843 |
PLN02843 |
isoleucyl-tRNA synthetase |
10-626 |
3.85e-99 |
|
isoleucyl-tRNA synthetase
Pssm-ID: 215452 [Multi-domain] Cd Length: 974 Bit Score: 338.67 E-value: 3.85e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 10 NFPAEEEKILEFWTEFNCFQECLKQSKHKPkFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHG 89
Cdd:PLN02843 4 NSVTREPEIQKLWEENQVYKRVSDRNNGES-FTLHDGPPYANGDLHIGHALNKILKDFINRYQLLQGKKVHYVPGWDCHG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 90 LPVEYEIDKTLGirgPEDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDK 169
Cdd:PLN02843 83 LPIELKVLQSLD---QEARKELTPIKLRAKAAKFAKKTVDTQRESFKRYGVWGDWENPYLTLDPEYEAAQIEVFGQMFLN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 170 GLVYRGVKVMPFSTACNTPLSnfESHQNYKDVQ-DPSVFVTFPL---------EEDE---TVSLVAWTTTPWTLPSNLAV 236
Cdd:PLN02843 160 GYIYRGRKPVHWSPSSRTALA--EAELEYPEGHvSKSIYVAFPVvspsetspeELEEflpGLSLAIWTTTPWTMPANAAV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 237 CVNPEMQY--VKIKDVA---------------------RGRLLILMEARLSAL-YKLESDYEILERFPGAYLKGKKYR-P 291
Cdd:PLN02843 238 AVNDKLQYsvVEVQSFSedestsggnkkkrpgnvlkeqQKLFLIVATDLVPALeAKWGVKLVVLKTFPGSDLEGCRYIhP 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 292 LFDYflKCKengafTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMdfniirKDSLP-VCPVDASGCFTTEVTDFAGQYV 370
Cdd:PLN02843 318 LYNR--ESP-----VVIGGDYITTESGTGLVHTAPGHGQEDYITGL------KYGLPlLSPVDDAGKFTEEAGQFSGLSV 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 371 -KDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDLCYWVPElVREKRFGNWL 449
Cdd:PLN02843 385 lGEGNAAVVEALDEAGSLLMEEAYGHKYPYDWRTKKPTIFRATEQWFASVEGFRQAALDAIDKVKWIPA-QGENRIRAMV 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 450 KDARDWTISRNRYWGTPIPLWVSDDFEEVV----CIGSVAELEELSGA------KISDLHRESVDHLTipsrcgkGSLHR 519
Cdd:PLN02843 464 SGRSDWCISRQRTWGVPIPVFYHVETKEPLmneeTIAHVKSIVAQKGSdawwymDVEDLLPEKYRDKA-------SDYEK 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 520 ISEVFDCWFESGSmPYAQVhypfeNKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQ 599
Cdd:PLN02843 537 GTDTMDVWFDSGS-SWAGV-----LGSREGLSYPADLYLEGSDQHRGWFQSSLLTSVATKGKAPYKSVLTHGFVLDEKGF 610
|
650 660 670
....*....|....*....|....*....|....*.
gi 1811715223 600 KMSKRKKNYPDPVSII-----QK----YGADALRLY 626
Cdd:PLN02843 611 KMSKSLGNVVDPRLVIeggknQKqepaYGADVLRLW 646
|
|
| valS |
PRK14900 |
valyl-tRNA synthetase; Provisional |
15-827 |
4.27e-62 |
|
valyl-tRNA synthetase; Provisional
Pssm-ID: 237855 [Multi-domain] Cd Length: 1052 Bit Score: 231.42 E-value: 4.27e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 15 EEKILEFWTEFNCFQeCLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEY 94
Cdd:PRK14900 25 EARWYPFWQERGYFH-GDEHDRTRPPFSIVLPPPNVTGSLHLGHALTATLQDVLIRWKRMSGFNTLWLPGTDHAGIATQM 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 95 EIDKTLgiRGPEDVAK--MGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLV 172
Cdd:PRK14900 104 IVEKEL--KKTEKKSRhdLGREAFLERVWAWKEQYGSRIGEQHKALGASLDWQRERFTMDEGLSRAVREVFVRLHEEGLI 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 173 YRGVKVMPFSTACNTPLSNFE-SHQNYKDVQDPSVfvTFPLEeDETVSLVAWTTTPWTLPSNLAVCVNPEmqyvkikdva 251
Cdd:PRK14900 182 YREKKLINWCPDCRTALSDLEvEHEEAHQGELWSF--AYPLA-DGSGEIVVATTRPETMLGDTAVAVHPL---------- 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 252 rgrllilmEARLSALYklesdyeilerfpgaylkGKKYR-PLFDYFLKCKengAFTVLVDnyvkEEEGTGVVHQAPyfgA 330
Cdd:PRK14900 249 --------DPRYMALH------------------GKKVRhPITGRTFPIV---ADAILVD----PKFGTGAVKVTP---A 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 331 EDYRvcmDFNIIRKDSLPVCPV-DASGCFTTEVTDFAGQYVKDADKSIIRTLKEQGrlLVATTFTHSYPF--CWRSDTPL 407
Cdd:PRK14900 293 HDFN---DFEVGKRHGLEMITViGPDGRMTAEAGPLAGLDRFEARKEVKRLLAEQG--LDRGAKPHVLPLgrCQRSATIL 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 408 IYKAVPSWFVRVENMVDQLLR--NNDLCYWVPELVREKRFGnWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCigsva 485
Cdd:PRK14900 368 EPLLSDQWYVRIEPLARPAIEavEQGRTRFIPEQWTNTYMA-WMRNIHDWCISRQLWWGHQIPAWYCPDGHVTVA----- 441
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 486 eleelsgakisdlhRESVDHLtipSRCGKGSLHRISEVFDCWFESGSMPYAQVHYPfENKREFEDAFPADFIAEGIDQTR 565
Cdd:PRK14900 442 --------------RETPEAC---STCGKAELRQDEDVLDTWFSSGLWPFSTMGWP-EQTDTLRTFYPTSVMETGHDIIF 503
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 566 GWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLInSPVVRAENLRFKE--- 642
Cdd:PRK14900 504 FWVARMMMMGLHFMGEVPFRTVYLHPMVRDEKGQKMSKTKGNVIDPLVITEQYGADALRFTLA-ALTAQGRDIKLAKeri 582
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 643 EGVRDVLKDVllpwYNAYRFLIQNVLrlqkeeeiEFLYNENTVRESP-NITDRWILSFMQ-------------------- 701
Cdd:PRK14900 583 EGYRAFANKL----WNASRFALMNLS--------GYQERGEDPARLArTPADRWILARLQravnetvealeafrfndaan 650
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 702 SLIGFFETEM-------------GEN-GMEDCVMAleTLFSVLLSLCRLMAPYTPFLTELMYQNLKVLIDPVSVQDkdtl 767
Cdd:PRK14900 651 AVYAFVWHELcdwyielakealaSEDpEARRSVQA--VLVHCLQTSYRLLHPFMPFITEELWHVLRAQVGASAWAD---- 724
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1811715223 768 SIHYLMLPRVREelIDKKTESAVSQMQSVIELGRVIRDRKTIPIKYPL---KEIVVIHQDPEA 827
Cdd:PRK14900 725 SVLAAEYPRKGE--ADEAAEAAFRPVLGIIDAVRNIRGEMGIPWKVKLgaqAPVEIAVADPAL 785
|
|
| valS |
PRK05729 |
valyl-tRNA synthetase; Reviewed |
12-855 |
1.79e-60 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 235582 [Multi-domain] Cd Length: 874 Bit Score: 224.21 E-value: 1.79e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 12 PAE-EEKILEFWTEFNCFQeclKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDrrfgWdchgL 90
Cdd:PRK05729 11 PKEvEAKWYQKWEEKGYFK---PDDNSKKPFSIVIPPPNVTGSLHMGHALNNTLQDILIRYKRMQGYNTL----W----L 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 91 P------------VEYEIDKTlgirgpedvakmGITeynnqcraivmRYSA----------EWK--------STVSRLGR 140
Cdd:PRK05729 80 PgtdhagiatqmvVERQLAAE------------GKS-----------RHDLgrekflekvwEWKeesggtitNQLRRLGA 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 141 WIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFEShqNYKDVQDPSVFVTFPLEEDETVSL 220
Cdd:PRK05729 137 SCDWSRERFTMDEGLSKAVREVFVRLYEKGLIYRGKRLVNWDPKLQTALSDLEV--EYKEVKGKLWHIRYPLADGSDYLV 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 221 VAwTTTPWTLPSNLAVCVNPEmqyvkikdvargrllilmearlsalyklesDyeilERFpgAYLKGKKYR-PLFDYFLKc 299
Cdd:PRK05729 215 VA-TTRPETMLGDTAVAVNPE------------------------------D----ERY--KHLIGKTVIlPLVGREIP- 256
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 300 kengaftVLVDNYVKEEEGTGVV-----HqapyfgaedyrvcmDFN---IIRKDSLPVCPV-DASGCFTTEVTDFAGQYV 370
Cdd:PRK05729 257 -------IIADEYVDPEFGTGAVkitpaH--------------DPNdfeVGKRHNLPMINImDEDGTINENPGEYQGLDR 315
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 371 KDADKSIIRTLKEQGrLLVAT-TFTHSYPFCWRSDT---PLIYKavpSWFVRVENMVDQLL---RNNDLCYwVPElvR-E 442
Cdd:PRK05729 316 FEARKAIVADLEELG-LLVKIePHTHSVGHSDRSGVviePYLSD---QWFVKMKPLAKPALeavENGEIKF-VPE--RwE 388
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 443 KRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVvcigsVAELEelsgakisdlhresvdhltiPSRCGKGSLHRISE 522
Cdd:PRK05729 389 KTYFHWMENIQDWCISRQLWWGHRIPAWYDEDGEVY-----VGREE--------------------PEAREKALLTQDED 443
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 523 VFDCWFESGSMPYAQVHYPfENKREFEDAFPADfiaegidqtrgwfytllVLATA---LF--------------GQPPFK 585
Cdd:PRK05729 444 VLDTWFSSALWPFSTLGWP-EKTEDLKRFYPTS-----------------VLVTGfdiIFfwvarmimmglhftGQVPFK 505
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 586 NVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLI--NSPvvrAENLRFKE---EGVRDV---LkdvllpwY 657
Cdd:PRK05729 506 DVYIHGLVRDEQGRKMSKSKGNVIDPLDLIDKYGADALRFTLAalASP---GRDIRFDEervEGYRNFankL-------W 575
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 658 NAYRFLIQNVLRLQKEEEIEflynentvRESPNITDRWILSFMQSLIG----FFET-EMGENGM---------------- 716
Cdd:PRK05729 576 NASRFVLMNLEGADVGELPD--------PEELSLADRWILSRLNRTVAevteALDKyRFDEAARalyefiwnefcdwyle 647
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 717 --------EDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLKVLIDPVSvqdkdtlsihyLML---PRVREELiDKK 785
Cdd:PRK05729 648 lakpvlqeAAKRATRATLAYVLEQILRLLHPFMPFITEELWQKLAPLGIEES-----------IMLapwPEADEAI-DEA 715
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 786 TESAVSQMQSVIELGRVIRDRKTIPIKYPLKeIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNK 855
Cdd:PRK05729 716 AEAEFEWLKELITAIRNIRAEMNIPPSKKLP-LLLKGADAEDRARLEANEAYIKRLARLESLEILADDEE 784
|
|
| ValS |
COG0525 |
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase ... |
12-853 |
8.56e-59 |
|
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440291 [Multi-domain] Cd Length: 877 Bit Score: 219.15 E-value: 8.56e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 12 PAE-EEKILEFWTEFNCFQEclKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVdrrfGWdchgL 90
Cdd:COG0525 9 PKEvEAKWYQYWEENGYFKA--DPDSDKEPFTIVIPPPNVTGSLHMGHALNNTLQDILIRYKRMQGYNT----LW----Q 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 91 P------------VEYEIDKTlgirgpedvakmGITeynnqcraivmRYSA----------EWK----STVS----RLGR 140
Cdd:COG0525 79 PgtdhagiatqavVERQLAEE------------GKS-----------RHDLgrekflervwEWKeesgGTITnqlrRLGA 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 141 WIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFEShqNYKDVQDPSVFVTFPLEEDETVSL 220
Cdd:COG0525 136 SCDWSRERFTMDEGLSKAVREVFVRLYEKGLIYRGKRLVNWDPKLKTALSDLEV--EHEEVKGHLWHIRYPLADGSGYIV 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 221 VAwTTTPWTLPSNLAVCVNPEmqyvkikdvargrllilmearlsalyklesDyeilERFpgAYLKGKKYR-PLFdyflkc 299
Cdd:COG0525 214 VA-TTRPETMLGDTAVAVHPE------------------------------D----ERY--KHLIGKTVIlPLV------ 250
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 300 keNGAFTVLVDNYVKEEEGTGVV-----HqapyfgaedyrvcmDFN---IIRKDSLPVCPV-DASGCFTTEVTDFAGQYV 370
Cdd:COG0525 251 --GREIPIIADEYVDPEFGTGAVkitpaH--------------DPNdfeVGKRHNLPMINIlDEDGTINENAGKYRGLDR 314
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 371 KDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDT---PLIykavpS--WFVRVENMVDQLL---RNNDLcYWVPElvR- 441
Cdd:COG0525 315 FEARKAIVADLEELGLLVKVEPHKHSVGHSDRSGTviePYL-----SdqWFVKMKPLAKPAIeavEDGEI-KFVPE--Rw 386
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 442 EKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDfEEVVcigsVAELEElsgakisdlhresvdhlTIPSRCGKGSLHRIS 521
Cdd:COG0525 387 EKTYFHWMENIRDWCISRQLWWGHRIPAWYCPD-GEVY----VARTEP-----------------EACAKAGSVNLTQDE 444
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 522 EVFDCWFESGSMPYAQVHYPFENKrEFEDAFPADfiaegidqtrgwfytllVLATA---LF--------------GQPPF 584
Cdd:COG0525 445 DVLDTWFSSALWPFSTLGWPEKTE-DLKYFYPTS-----------------VLVTGfdiIFfwvarmimmglhftGEVPF 506
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 585 KNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLI--NSPvvrAENLRFKE---EGVRDV---LkdvllpW 656
Cdd:COG0525 507 KDVYIHGLVRDEQGRKMSKSKGNVIDPLDLIDKYGADALRFTLAalASP---GRDIKFDEervEGYRNFankL------W 577
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 657 yNAYRFLIQNvlrlqkeeEIEFLYNENTVRESPNITDRWILSFMQSLIG----FFET----------------------- 709
Cdd:COG0525 578 -NASRFVLMN--------LEGFDPGLDPDPEELSLADRWILSRLNKTIAevteALEKyrfdeaaqalydfvwnefcdwyl 648
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 710 EM------GENGMEDCVmALETLFSVLLSLCRLMAPYTPFLTELMYQNLKVLIDPVSvqdkdtlsihyLML---PRVREE 780
Cdd:COG0525 649 ELakprlyGGDEAAKRE-TRATLVYVLEQILRLLHPFMPFITEEIWQKLPPRKEGES-----------IMLapwPEADEE 716
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1811715223 781 LIDKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKeIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDK 853
Cdd:COG0525 717 LIDEEAEAEFEWLKEVISAIRNIRAEMNIPPSKKLP-LLLKGADEADRARLEENAAYIKRLARLEEITILVDE 788
|
|
| Anticodon_Ia_Ile_ABEc |
cd07961 |
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA ... |
640-801 |
7.27e-56 |
|
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial, archaeal, and eukaryotic cytoplasmic members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153415 [Multi-domain] Cd Length: 183 Bit Score: 191.61 E-value: 7.27e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 640 FKEEGVRDVLKDVLLPWYNAYRFLIQNVLRLQKEEEieflyNENTVRESPNITDRWILSFMQSLIGFFETEM-------- 711
Cdd:cd07961 1 FSEKGVREVVRKVLLPLWNAYRFFVTYANLDGFDPG-----KDDDAVASLNVLDRWILSRLNSLIKEVTEEMeaydlyta 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 712 ------------------------GENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLKVLIdpvsvqDKDTL 767
Cdd:cd07961 76 vrallefideltnwyirrnrkrfwGEEGDDDKLAAYATLYEVLLTLSRLMAPFTPFITEEIYQNLRREL------GDAPE 149
|
170 180 190
....*....|....*....|....*....|....
gi 1811715223 768 SIHYLMLPRVREELIDKKTESAVSQMQSVIELGR 801
Cdd:cd07961 150 SVHLLDWPEVDESLIDEELEEAMELVREIVELGR 183
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
47-630 |
6.94e-53 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 190.54 E-value: 6.94e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 47 PPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDvAKMGITEYNNQCRAIVMR 126
Cdd:cd00817 9 PPNVTGSLHMGHALNNTIQDIIARYKRMKGYNVLWPPGTDHAGIATQVVVEKKLGIEGKTR-HDLGREEFLEKCWEWKEE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 127 YSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVyrgvkvmpfstacntplsnfeshqnYKDVQdpsv 206
Cdd:cd00817 88 SGGKIREQLKRLGASVDWSREYFTMDPGLSRAVQEAFVRLYEKGLI-------------------------YRDNR---- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 207 fvtfpleedetvsLVAWTTTpwtlpsnlavCvnpemqyvkikdvargrllilmearLSALykleSDYEIlerfpgaylkg 286
Cdd:cd00817 139 -------------LVNWCPK----------L-------------------------RTAI----SDIEV----------- 155
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 287 kkyrplfdyflkckengaftvlvdnyvkeeegtgvvhqapyfgaedyrvcmdfniirkdslpvcpvdasgcfttevtdfa 366
Cdd:cd00817 --------------------------------------------------------------------------------
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 367 gqyvkdadksiirtlkeqgrllvattfthsypfCWRSDTPLIYKAVPSWFVRVENMVDQLLR--NNDLCYWVPELVrEKR 444
Cdd:cd00817 156 ---------------------------------CSRSGDVIEPLLKPQWFVKVKDLAKKALEavKEGDIKFVPERM-EKR 201
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 445 FGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVcigsVAELEELSGAKISDLHREsvdhltipsRCGKGSLHRISEVF 524
Cdd:cd00817 202 YENWLENIRDWCISRQLWWGHRIPAWYCKDGGHWV----VAREEDEAIDKAAPEACV---------PCGGEELKQDEDVL 268
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 525 DCWFESGSMPYAQVHYPfENKREFEDAFPADFIAEGIDQTRGW-FYTLLvLATALFGQPPFKNVIVNGLVLASDGQKMSK 603
Cdd:cd00817 269 DTWFSSSLWPFSTLGWP-EETKDLKKFYPTSLLVTGHDIIFFWvARMIM-RGLKLTGKLPFKEVYLHGLVRDEDGRKMSK 346
|
570 580
....*....|....*....|....*..
gi 1811715223 604 RKKNYPDPVSIIQKYGADALRLYLINS 630
Cdd:cd00817 347 SLGNVIDPLDVIDGYGADALRFTLASA 373
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
390-628 |
1.06e-49 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 179.15 E-value: 1.06e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 390 ATTFTHSYPFCWRS-----DTPLIYK------AVPSWFVRVENMVDQLLRNNDLCYWVPELVReKRFGNWLKDARDWTIS 458
Cdd:cd00668 106 ITTEPEYSKAVELIfsrlyEKGLIYRgthpvrITEQWFFDMPKFKEKLLKALRRGKIVPEHVK-NRMEAWLESLLDWAIS 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 459 RNRYWGTPIPLWVsddfeevvcigsvaeleelsgakisdlhresvdhltipsrcgkgslhrisevFDCWFESGSMPYAQV 538
Cdd:cd00668 185 RQRYWGTPLPEDV----------------------------------------------------FDVWFDSGIGPLGSL 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 539 HYPFENkREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKY 618
Cdd:cd00668 213 GYPEEK-EWFKDSYPADWHLIGKDILRGWANFWITMLVALFGEIPPKNLLVHGFVLDEGGQKMSKSKGNVIDPSDVVEKY 291
|
250
....*....|
gi 1811715223 619 GADALRLYLI 628
Cdd:cd00668 292 GADALRYYLT 301
|
|
| PTZ00419 |
PTZ00419 |
valyl-tRNA synthetase-like protein; Provisional |
15-855 |
2.09e-49 |
|
valyl-tRNA synthetase-like protein; Provisional
Pssm-ID: 240411 [Multi-domain] Cd Length: 995 Bit Score: 191.37 E-value: 2.09e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 15 EEKILEFWTEFNCFQ--ECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLP- 91
Cdd:PTZ00419 34 ESGWYEWWEKSGFFKpaEDAKSLNSGKKFVIVLPPPNVTGYLHIGHALTGAIQDSLIRYHRMKGDETLWVPGTDHAGIAt 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 92 ---VEYEIDKTLG-IR---GPEDVAKMgITEYNNQcraivmrYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFK 164
Cdd:PTZ00419 114 qvvVEKKLMKEENkTRhdlGREEFLKK-VWEWKDK-------HGNNICNQLRRLGSSLDWSREVFTMDEQRSKAVKEAFV 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 165 QLYDKGLVYRGVKVMPFSTACNTPLSNFEShqNYKDVQDPSVF----------------VTFPLEEDETVSLVAWTTTPW 228
Cdd:PTZ00419 186 RLYEDGLIYRDTRLVNWCCYLKTAISDIEV--EFEEIEKPTKItipgydkkvevgvlwhFAYPLEDSGQEEIVVATTRIE 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 229 TLPSNLAVCVNPemqyvkiKDvargrllilmearlsalyklesdyeilERFpgAYLKGKkyrplfdyFLKC---KENGAF 305
Cdd:PTZ00419 264 TMLGDVAVAVHP-------KD---------------------------ERY--KKLHGK--------ELIHpfiPDRKIP 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 306 TVLVDNYVKEEEGTGVVHQAPyfgAEDYRvcmDFNIIRKDSLPVCPV-DASGCFTTEVTDFAGQYVKDADKSIIRTLKEQ 384
Cdd:PTZ00419 300 IIADDELVDMEFGTGAVKITP---AHDPN---DYEIAKRHNLPFINIfTLDGKINENGGEFAGMHRFDCRRKIEEELKEM 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 385 GRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQ---LLRNNDLCYWVPELVREkrFGNWLKDARDWTISRNR 461
Cdd:PTZ00419 374 GLLRDKVPNPMRLPRCSRSGDIVEPMLIPQWYVNCKDMAKRaveAVRNGELKIIPSSHENV--WYHWLENIQDWCISRQL 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 462 YWGTPIP-----------------LWV-SDDFEEvvCIGSVAELEELSGAKISdlhresvdhltipsrcgkgsLHRISEV 523
Cdd:PTZ00419 452 WWGHRIPayrviskgpetdpsdeePWVvARSEEE--ALEKAKKKFGLSEEDFE--------------------LEQDEDV 509
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 524 FDCWFESGSMPYAQVHYPfENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSK 603
Cdd:PTZ00419 510 LDTWFSSGLFPFSTLGWP-DQTDDLQRFFPTSLLETGSDILFFWVARMVMMSLHLTDKLPFKTVFLHAMVRDSQGEKMSK 588
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 604 RKKNYPDPVSIIQKYGADAL--RLYLINSP---VVRAENLRFKE--EGV-------------------RDVLKDV----- 652
Cdd:PTZ00419 589 SKGNVIDPLEVIEGISLQDLnqKLYEGNLPekeIKRAIELQKKEfpNGIpecgtdalrfgllaytqqgRNINLDInrvvg 668
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 653 -------LlpWyNAYRFLIQNVLRLQKeeEIEFLYNENTVRESPNITDRWILSFMQSLI-----GFFETEMGE------- 713
Cdd:PTZ00419 669 yrhfcnkL--W-NAVKFALMKLLKDFN--LPNSTLFKPNNVESLPWEDKWILHRLNVAIkevteGFKEYDFSEatqatyn 743
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 714 ---------------------NGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLkvlidPVSVQDKDTLSI-HY 771
Cdd:PTZ00419 744 fwlyelcdvylelikprlskqSDGERKQHAQDVLHTVLDIGLRLLHPMMPFITEELYQRL-----PNYLRKSESISIaKY 818
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 772 lmlPRVREELIDKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPeaLKDIKSLEKYIIEEL-NVRKVTLS 850
Cdd:PTZ00419 819 ---PQPNPGWNNEALDEEMKIIMSIVKSIRSLIATLGIPNKTKPDCYVTAKDAE--LIELIESAENLISTLaKIGSVSVI 893
|
....*
gi 1811715223 851 TDKNK 855
Cdd:PTZ00419 894 PPIEE 898
|
|
| PLN02943 |
PLN02943 |
aminoacyl-tRNA ligase |
13-752 |
1.09e-48 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215509 [Multi-domain] Cd Length: 958 Bit Score: 188.61 E-value: 1.09e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 13 AEEEKILEFWTEFNCFQECLKQSKHKpkFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPV 92
Cdd:PLN02943 64 TSEERIYNWWESQGYFKPNFDRGGDP--FVIPMPPPNVTGSLHMGHAMFVTLEDIMVRYNRMKGRPTLWIPGTDHAGIAT 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 93 EYEIDKTLGIRGPEDVaKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLV 172
Cdd:PLN02943 142 QLVVEKMLASEGIKRT-DLGRDEFTKRVWEWKEKYGGTITNQIKRLGASCDWSRERFTLDEQLSRAVVEAFVRLHEKGLI 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 173 YRGVKVMPFSTACNTPLSNFESHqnYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPE----MQYVkik 248
Cdd:PLN02943 221 YQGSYMVNWSPNLQTAVSDLEVE--YSEEPGTLYYIKYRVAGGSEDFLTIATTRPETLFGDVAIAVNPEddrySKYI--- 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 249 dvarGRLLILmearlsalyklesdyeilerfPgayLKGKKYRPlfdyflkckengaftVLVDNYVKEEEGTGVVHQAPYF 328
Cdd:PLN02943 296 ----GKMAIV---------------------P---MTYGRHVP---------------IIADRYVDKDFGTGVLKISPGH 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 329 GAEDYRvcmdfnIIRKDSLPVCPV---DASgcftteVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDT 405
Cdd:PLN02943 333 DHNDYL------LARKLGLPILNVmnkDGT------LNEVAGLYWFEAREKLWSDLEETGLAVKKEPHTLRVPRSQRGGE 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 406 ---PLIYKavpSWFVRVENMVDQLLR---NNDLCYwVPELVrEKRFGNWLKDARDWTISRNRYWGTPIPLW--VSDDFEE 477
Cdd:PLN02943 401 viePLVSK---QWFVTMEPLAEKALKaveNGELTI-IPERF-EKIYNHWLSNIKDWCISRQLWWGHRIPVWyiVGKDCEE 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 478 VVCigsVAELEELSGAKISDLHRESVDhltipsrcgkgsLHRISEVFDCWFESGSMPYAQVHYPFENKREFEDAFPADFI 557
Cdd:PLN02943 476 DYI---VARSAEEALEKAREKYGKDVE------------IYQDPDVLDTWFSSALWPFSTLGWPDVSAEDFKKFYPTTVL 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 558 AEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAEN 637
Cdd:PLN02943 541 ETGHDILFFWVARMVMMGIEFTGTVPFSYVYLHGLIRDSQGRKMSKTLGNVIDPLDTIKEFGTDALRFTLALGTAGQDLN 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 638 LRFKEEGVRDVLKDVLlpwYNAYRFLIQNVLRLQKEEEIEFLYN-----ENTVRESPnITDRWILSFMQSLIG------- 705
Cdd:PLN02943 621 LSTERLTSNKAFTNKL---WNAGKFVLQNLPSQSDTSAWEHILAckfdkEESLLSLP-LPECWVVSKLHELIDsvttsyd 696
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1811715223 706 -FFETEMGE-------------------------NGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNL 752
Cdd:PLN02943 697 kYFFGDVGReiydffwsdfadwyieasktrlyhsGDNSALSRAQAVLLYVFENILKLLHPFMPFVTEELWQAL 769
|
|
| leuS_bact |
TIGR00396 |
leucyl-tRNA synthetase, eubacterial and mitochondrial family; The leucyl-tRNA synthetases ... |
10-838 |
3.02e-39 |
|
leucyl-tRNA synthetase, eubacterial and mitochondrial family; The leucyl-tRNA synthetases belong to two families so broadly different that they are represented by separate models. This model includes both eubacterial and mitochondrial leucyl-tRNA synthetases. It generates higher scores for some valyl-tRNA synthetases than for any archaeal or eukaryotic cytosolic leucyl-tRNA synthetase. Note that the enzyme from Aquifex aeolicus is split into alpha and beta chains; neither chain is long enough to score above the trusted cutoff, but the alpha chain scores well above the noise cutoff. The beta chain must be found by a model and search designed for partial length matches. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273057 [Multi-domain] Cd Length: 842 Bit Score: 157.99 E-value: 3.02e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 10 NFPAEEEKILEFWTEFNCFQecLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHG 89
Cdd:TIGR00396 2 NHIEIEEKWQQKWDENKTFK--VTDDSSKPKYYILSMFPYPSGALHMGHVRNYTITDVLSRYYRMKGYNVLHPIGWDAFG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 90 LPVE-YEIDKtlGIRgPEDVAKMGITEYNNQCRAivmrysaewkstvsrLGRWIDFDNDYKTLYPQFMESVWWVFKQLYD 168
Cdd:TIGR00396 80 LPAEnAAIKR--GIH-PAKWTYENIANMKKQLQA---------------LGFSYDWDREIATCDPEYYKWTQWIFLELFE 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 169 KGLVYRgvKVMPF--------------------STACNTP--------------------LSNFES----HQNYKDVQ-- 202
Cdd:TIGR00396 142 KGLAYV--KEADVnwcpndgtvlaneqvdsdgrSWRGDTPvekkelkqwflkitayaeelLNDLEEldhwPESVKEMQrn 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 203 ----DPSVFVTFPLEeDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKikdvargrLLILMEARLSALYKLESDYEILER 278
Cdd:TIGR00396 220 wigkSEGVEITFKIA-DHDEKITVFTTRPDTIFGVTYLALAPEHPLVE--------KAAENNPKVAAFIKKILNKTVAER 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 279 FP------GAYLKGKKYRPLfdyflkckENGAFTVLVDNYVKEEEGTGVVHQAPyfgAEDYRvcmDFNIIRKDSLPVCPV 352
Cdd:TIGR00396 291 TKatkekkGVDTGIKAIHPL--------TGEKIPIWVANYVLMEYGTGAVMGVP---AHDER---DFEFAQKYGLPIKPV 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 353 dasgcfttevTDFAGQyvkdaDKSIIRTLKEQGRLLVATTFTHSypfcwrsDTPLIYKAVPSWFVrvENMVDQLLRNNDL 432
Cdd:TIGR00396 357 ----------IDPAEK-----DLSLTAAYTEDGVLVNSGEFNGL-------NSSEARNAIIDMLE--KEGKGKRKVNYRL 412
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 433 cywvpelvrekrfgnwlkdaRDWTISRNRYWGTPIPLWVSDDFEEVVCIGS-----VAELEELSGAKISDLHR-ESVDHL 506
Cdd:TIGR00396 413 --------------------RDWGFSRQRYWGEPIPIIHCEDGGVVPVPEEdlpviLPEDVVYDGDGGSPLSRiPEWVNV 472
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 507 TIPSrCGKGSLhRISEVFDCWFESG--SMPYAQVHYP--FENKREFEDAFPADFIAEGIDQT-------RgWFYTLLVLA 575
Cdd:TIGR00396 473 TCPS-CGKPAL-RETDTMDTFAGSSwyYLRYLDPKNTdgPFDKEKAEYWLPVDLYIGGIEHAilhllyaR-FFHKFLRDI 549
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 576 TALFGQPPFKNVIVNGLVLA-------------------------------SDGQKMSKRKKNYPDPVSIIQKYGADALR 624
Cdd:TIGR00396 550 GYVNTKEPFKKLINQGMVLGfyyppngkvpadvlterdekgkdkaggelvyVGYEKMSKSKGNGIDPQEIVESYGADALR 629
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 625 LYLI-NSPVvrAENLRFKE---EGVRDVLKDVLLPWYN-----AYRFLIQNVLRlQKEEEIEFLYNEnTVRESPNITDR- 694
Cdd:TIGR00396 630 LFIMfMGPI--AASLEWNEsglEGARRFLDRVWNLVYEitgelDAASLTVTALE-EAQKELRRDVHK-FLKKVTEDLEKr 705
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 695 ----WILSFMQSLIGFFETEmgengmEDCVMALETLFSVLlslcRLMAPYTPFLTELMYQNLKVLidpvsvqdkdTLSIH 770
Cdd:TIGR00396 706 esfnTAISAMMELLNKLYKA------KKEALMLEYLKGFV----TVLSPFAPHLAEELWEKLGSE----------PFIID 765
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1811715223 771 YLMLPRVREELIDKktesavSQMQSVIELGRVIRDRKTIPIKYPLKEIVVI-HQDPEALKDI--KSLEKYI 838
Cdd:TIGR00396 766 NAKWPVVDETALVE------DKTLIVVQVNGKFRAKITVPKDADEEQVEELaKQDPEVKKYLenKTIKKVI 830
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
40-178 |
7.21e-37 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 141.79 E-value: 7.21e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 40 KFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGpedvaKMGITEYNNQ 119
Cdd:cd00668 1 KFYVTTPPPYANGSLHLGHALTHIIADFIARYKRMRGYEVPFLPGWDTHGLPIELKAERKGGRKK-----KTIWIEEFRE 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 120 -CRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKV 178
Cdd:cd00668 76 dPKEFVEEMSGEHKEDFRRLGISYDWSDEYITTEPEYSKAVELIFSRLYEKGLIYRGTHP 135
|
|
| leuS |
PRK12300 |
leucyl-tRNA synthetase; Reviewed |
54-918 |
8.66e-37 |
|
leucyl-tRNA synthetase; Reviewed
Pssm-ID: 237049 [Multi-domain] Cd Length: 897 Bit Score: 150.79 E-value: 8.66e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 54 PHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVeyeidktLGI-----RGPEDVakmgITEYNNQCR------- 121
Cdd:PRK12300 1 LHVGHGRTYTIGDVIARYKRMRGYNVLFPMAFHVTGTPI-------LGIaeriaRGDPET----IELYKSLYGipeeele 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 122 ------AIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLsnfESH 195
Cdd:PRK12300 70 kfkdpeYIVEYFSEEAKEDMKRIGYSIDWRREFTTTDPEYSKFIEWQFRKLKEKGLIVKGSHPVRYCPNDNNPV---GDH 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 196 qNYKDVQDPSV--FVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKdvARGRLLILMEArlsALYKL---E 270
Cdd:PRK12300 147 -DLLDGEEPEIveYTLIKFEESEDLILPAATLRPETIFGVTNLWVNPDATYVKAE--VDGEKWIVSKE---AAEKLsfqD 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 271 SDYEILERFPGAYLKGKKYR-PLFDyflkcKEngaFTVLVDNYVKEEEGTGVV-----HqAPYfgaeDYRVCMDFNIIRK 344
Cdd:PRK12300 221 RDVEIIEEIKGSELIGKKVKnPVTG-----KE---VPILPADFVDPDNGTGVVmsvpaH-APY----DYVALRDLKKNKE 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 345 DS-----LPVCPVDASGCF----------------------TTEV--------------TDFAGQYVKDADKSIIRTLKE 383
Cdd:PRK12300 288 LLdviepIPLIEVEGYGEFpakevveklgiksqedpeleeaTKEVyraefhkgvlkentGEYAGKPVREAREKITKDLIE 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 384 QGRLLVATTFTHSYPFCwRSDTPLIYKAVP-SWFV---------RVENMVDQLlrnnDLcywVPELVReKRFGN---WLK 450
Cdd:PRK12300 368 KGIADIMYEFSNRPVYC-RCGTECVVKVVKdQWFIdysdpewkeLAHKALDNM----EI---IPEEYR-KEFENtidWLK 438
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 451 darDWTISRNRYWGTPIPlWvsdDFEEVVcigsvaelEELS------------------GAKISDLHRESVDHLTIpsrc 512
Cdd:PRK12300 439 ---DRACARRRGLGTRLP-W---DEEWII--------ESLSdstiymayytiahkireyGIKPEQLTPEFFDYVFL---- 499
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 513 GKGSLHRISEvfdcwfESGsMPYAQVHypfENKREFEDAFPADFIAEGIDqtrgwfytlLV---LA------TALFGQ-- 581
Cdd:PRK12300 500 GKGDPEEVSK------KTG-IPKEILE---EMREEFLYWYPVDWRHSGKD---------LIpnhLTffifnhVAIFPEek 560
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 582 -PpfKNVIVNGLVLaSDGQKMSKRKKNYPDPVSIIQKYGADALRLYLINSpvvrAE-----NLRFKE-EGVRDVLKDvll 654
Cdd:PRK12300 561 wP--RGIVVNGFVL-LEGKKMSKSKGNVIPLRKAIEEYGADVVRLYLTSS----AEllqdaDWREKEvESVRRQLER--- 630
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 655 pWYNayrfLIQNVLRLQKEEEIEFLynentvrespnitDRWILSFMQSLI------------------GFFET------- 709
Cdd:PRK12300 631 -FYE----LAKELIEIGGEEELRFI-------------DKWLLSRLNRIIketteamesfqtrdavqeAFYELlndlrwy 692
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 710 -EMGEngmEDCVMALETLFSVLLslcRLMAPYTPFLTELMYQNLKVLiDPVSVQDkdtlsihylmLPRVREELIDKKTES 788
Cdd:PRK12300 693 lRRVG---EANNKVLREVLEIWI---RLLAPFTPHLAEELWHKLGGE-GFVSLEK----------WPEPDESKIDEEAEL 755
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 789 AVSQMQSVIElgrvirdrktipikyplkeivvihqdpealkDIKSLEKYIieELNVRKVTLST-DKNKYGIrLRAEPDHM 867
Cdd:PRK12300 756 AEEYVKRLIE-------------------------------DIREILKVA--KIKPKKVYIYVaPDWKYEV-LEIAAENG 801
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|.
gi 1811715223 868 VLGKRLKGAFKAVmtSIKQLSSEELEQFQKtgtIVVEGHELHDEDIRLMYT 918
Cdd:PRK12300 802 DVKEAIKELMKDE--ELRKHGKEVAKLAQK---IVKEVLKLDKEVRKLILK 847
|
|
| PLN02381 |
PLN02381 |
valyl-tRNA synthetase |
4-623 |
1.66e-29 |
|
valyl-tRNA synthetase
Pssm-ID: 215214 [Multi-domain] Cd Length: 1066 Bit Score: 127.71 E-value: 1.66e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 4 QVPENINFPAEEEKILEFWTEFNCFQECLKQSKhkPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRF 83
Cdd:PLN02381 95 QMAKQYSPSAVEKSWYAWWEKSGYFGADAKSSK--PPFVIVLPPPNVTGALHIGHALTAAIEDTIIRWKRMSGYNALWVP 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 84 GWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQcraiVMRYSAEWKSTV----SRLGRWIDFDNDYKTLYPQFMESV 159
Cdd:PLN02381 173 GVDHAGIATQVVVEKKLMRERHLTRHDIGREEFVSE----VWKWKDEYGGTIlnqlRRLGASLDWSRECFTMDEQRSKAV 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 160 WWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFEShqNYKDVQDPS--------------VFVTF--PLEEDETVSLVAw 223
Cdd:PLN02381 249 TEAFVRLYKEGLIYRDIRLVNWDCTLRTAISDVEV--DYIDIKERTllkvpgydkpvefgVLTSFayPLEGGLGEIVVA- 325
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 224 TTTPWTLPSNLAVCVNPEmqyvkikdvargrllilmEARLSALYKlesdyeileRFPGAYLKGKKYRPLFDyflkckeng 303
Cdd:PLN02381 326 TTRIETMLGDTAIAIHPD------------------DERYKHLHG---------KFAVHPFNGRKLPIICD--------- 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 304 afTVLVD-NYvkeeeGTGVVHQAPYFGAEDYRV----CMDF-NIIRKDSlpvcPVDASGCfttevTDFAGQYVKDADKSI 377
Cdd:PLN02381 370 --AILVDpNF-----GTGAVKITPAHDPNDFEVgkrhNLEFiNIFTDDG----KINSNGG-----SEFAGMPRFAAREAV 433
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 378 IRTLKEQGRLLVATTFTHSYPFCWRSD---TPLIYkavPSWFVRVENMVDQLL------RNNDLCYWVPELVREKRfgNW 448
Cdd:PLN02381 434 IEALQKKGLYRGAKNNEMRLGLCSRTNdvvEPMIK---PQWFVNCSSMAKQALdaaidgENKKLEFIPKQYLAEWK--RW 508
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 449 LKDARDWTISRNRYWGTPIPLW---VSDDFEEVVCIGS----VAELEELSGAKISdlhresvdhLTIPSRcgKGSLHRIS 521
Cdd:PLN02381 509 LENIRDWCISRQLWWGHRIPAWyvtLEDDQLKELGSYNdhwvVARNESDALLEAS---------QKFPGK--KFELSQDP 577
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 522 EVFDCWFESGSMPYAQVHYPfENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKM 601
Cdd:PLN02381 578 DVLDTWFSSGLFPLSVLGWP-DDTDDLKAFYPTSVLETGHDILFFWVARMVMMGMQLGGDVPFRKVYLHPMIRDAHGRKM 656
|
650 660
....*....|....*....|..
gi 1811715223 602 SKRKKNYPDPVSIIQKYGADAL 623
Cdd:PLN02381 657 SKSLGNVIDPLEVINGISLEGL 678
|
|
| PLN02563 |
PLN02563 |
aminoacyl-tRNA ligase |
3-626 |
1.53e-19 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178177 [Multi-domain] Cd Length: 963 Bit Score: 95.28 E-value: 1.53e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 3 QQVPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLP-HYGHILAGTIKDIVTRYAHQSGFHVDR 81
Cdd:PLN02563 74 PAAKRAYPFHEIEPKWQRYWEENRTFRTPDDVDTSKPKFYVLDMFPYPSGAGlHVGHPEGYTATDILARYKRMQGYNVLH 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 82 RFGWDCHGLPVE-YEIDKtlGIRgPEDVAKMGITEYNNQCRAIVMRYsaewkstvsrlgrwiDFDNDYKTLYPQFMESVW 160
Cdd:PLN02563 154 PMGWDAFGLPAEqYAIET--GTH-PKITTLKNIARFRSQLKSLGFSY---------------DWDREISTTEPEYYKWTQ 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 161 WVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFE---------SH-------------------------------QNYKD 200
Cdd:PLN02563 216 WIFLQLLKRGLAYQAEVPVNWCPALGTVLANEEvvdglsergGHpvirkpmrqwmlkitayadrlledlddldwpESIKE 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 201 VQ------------DPSVFVTFPLEEDETVSLvaWTTTPWTLPSNLAVCVNPEMQYVkikdvarGRLLILMEARLSALYK 268
Cdd:PLN02563 296 MQrnwigrsegaelDFSVLDGEGKERDEKITV--YTTRPDTLFGATYLVVAPEHPLL-------SSLTTAEQKEAVEEYV 366
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 269 -LESDYEILER----------FPGAYLKgkkyRPLfdyflkckENGAFTVLVDNYVKEEEGTGVVHQAPyfgAEDYRvcm 337
Cdd:PLN02563 367 dAASRKSDLERtelqkektgvFTGSYAI----NPA--------TGEAIPIWVADYVLGSYGTGAIMAVP---AHDTR--- 428
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 338 DFNIIRKDSLPVCPV---------DASGCFTTEVT---------DFAGQYVKDADKSIIRtlkeqgrllvattfthsypf 399
Cdd:PLN02563 429 DFEFAQKFDLPIKWVvkpadgnedDAEKAYTGEGVivnssssglDINGLSSKEAAKKVIE-------------------- 488
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 400 cwrsdtpliykavpswfvrvenmvdqllrnndlcyWVPELVREKRFGNWlkDARDWTISRNRYWGTPIPLWVSDDFEEVV 479
Cdd:PLN02563 489 -----------------------------------WLEETGNGKKKVNY--KLRDWLFARQRYWGEPIPVVFLEDSGEPV 531
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 480 CIgSVAELEelsgakisdLHRESVDHLTiPSRCGKGSLHRISE---VFDC----WF--ESGSMP--------YAQVHYP- 541
Cdd:PLN02563 532 PV-PESDLP---------LTLPELDDFT-PTGTGEPPLAKAVSwvnTVDPssgkPArrETNTMPqwagscwyYLRFMDPk 600
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 542 -----FENKREfEDAFPADFIAEGIDQ-------TRGW---FYTLLVLATalfgQPPFKNVIVNGLVLA---------SD 597
Cdd:PLN02563 601 nsnalVDKEKE-KYWMPVDLYVGGAEHavlhllyARFWhkvLYDIGVVST----KEPFQCLVNQGMILGeveytafkdSD 675
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1811715223 598 GQ---------------------------------------------KMSKRKKNYPDPVSIIQKYGADALRLY 626
Cdd:PLN02563 676 GEyvsadtadrlgelqqekipeekviksgdsfvlkddpsirliarahKMSKSRGNVVNPDDVVSEYGADSLRLY 749
|
|
| DUF5915 |
pfam19302 |
Domain of unknown function (DUF5915); This presumed domain is found at the C-terminus of ... |
838-1001 |
2.98e-19 |
|
Domain of unknown function (DUF5915); This presumed domain is found at the C-terminus of isoleucyl tRNA ligase enzymes.
Pssm-ID: 437134 [Multi-domain] Cd Length: 195 Bit Score: 87.14 E-value: 2.98e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 838 IIEELNVRKVTLSTDKNKYgIRLRAEPDHMVLGKRLKGAFKAVMTSIKQLSSEELEQFQKTGT--IVVEGH--ELHDEDI 913
Cdd:pfam19302 4 IKEELNVKEVEFGADESEL-VEYSAKPNFPVLGKELGKLMKAAAKEIASLNQMEIQKILDGGTltIDVDGEeiELTSEDL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 914 RLmytfdQATGgTAQFEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEgtyLNSV 993
Cdd:pfam19302 83 LV-----TRQG-KEGLAVANEGTLTVALDTTITEELREEGLVREIVSKIQNLRKESGFEVTDRINLYVSGNEM---LEAA 153
|
....*...
gi 1811715223 994 IESHTEFI 1001
Cdd:pfam19302 154 IEKFEDYI 161
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
48-175 |
1.37e-14 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 76.13 E-value: 1.37e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 48 PFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTlgIRGPEDvakmgITEYNnqcraivmry 127
Cdd:cd00812 9 PYPSGALHVGHVRTYTIGDIIARYKRMQGYNVLFPMGFDAFGLPAENAAIKI--GRDPED-----WTEYN---------- 71
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1811715223 128 SAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRG 175
Cdd:cd00812 72 IKKMKEQLKRMGFSYDWRREFTTCDPEYYKFTQWLFLKLYEKGLAYKK 119
|
|
| LeuS |
COG0495 |
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA ... |
453-752 |
1.39e-12 |
|
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440261 [Multi-domain] Cd Length: 826 Bit Score: 72.39 E-value: 1.39e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 453 RDWTISRNRYWGTPIPLWVSDDfeevvCiGSVA-----------ELEELSGAKISDL--HRESVdHLTIPsRCGKgSLHR 519
Cdd:COG0495 420 RDWLISRQRYWGEPIPIIHCED-----C-GVVPvpedqlpvelpEDVDFDPTGGSPLarAPEWV-NVTCP-KCGG-PARR 490
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 520 ISEVFDCWFESgS---MPYAQVHYpfenkrefeDAFPADFIAE----GIDQ--------------TRgwFYTLLVLATAL 578
Cdd:COG0495 491 ETDTMDTFVDS-SwyyLRYTDPHN---------DEAPFDPEAAnywlPVDQyiggiehailhllyAR--FFTKVLRDLGL 558
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 579 FGQP-PFKNVIVNGLV--LASDG------QKMSKRKKNYPDPVSIIQKYGADALRLYLI-NSPVVRaeNLRFKEEGVRdv 648
Cdd:COG0495 559 VSFDePFKRLLTQGMVleVGKDGvviggiEKMSKSKGNVVDPDEIIEKYGADTLRLFEMfAGPPER--DLEWSDSGVE-- 634
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 649 lkdvllpwyNAYRFLiQNVLRL----------------QKEEEIEFLYNEnTVRESPNITDRW-----ILSFMqSLIGFF 707
Cdd:COG0495 635 ---------GAYRFL-NRVWRLvvdeaealkldvadlsEADKELRRALHK-TIKKVTEDIERLrfntaIAALM-ELVNAL 702
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1811715223 708 ETEMGENGMEDCVM--ALETlfsvllsLCRLMAPYTPFLTELMYQNL 752
Cdd:COG0495 703 YKAKDSGEADRAVLreALET-------LVLLLAPFAPHIAEELWERL 742
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
413-628 |
1.58e-12 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 69.97 E-value: 1.58e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 413 PSWFVRVENMVDQLLRnndlcywVPELVReKRFGNWLKdardwtISRNRYWGTPIPL-WVSDDFeevvcIGSvaeleels 491
Cdd:cd00812 139 TEWKEKLLKDLEKLDG-------WPEEVR-AMQENWIG------CSRQRYWGTPIPWtDTMESL-----SDS-------- 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 492 gakisdlhresvdhltipsrcgkgslhrisevfdCWFESGsmpYAQVHYPF--------ENKREFEDAFPADFIAEGIDQ 563
Cdd:cd00812 192 ----------------------------------TWYYAR---YTDAHNLEqpyegdleFDREEFEYWYPVDIYIGGKEH 234
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 564 -----TRGWFYTLLVLATALFGQPPFKNVIVNGLVLAsDGQKMSKRKKNYPDPVSIIQKYGADALRLYLI 628
Cdd:cd00812 235 apnhlLYSRFNHKALFDEGLVTDEPPKGLIVQGMVLL-EGEKMSKSKGNVVTPDEAIKKYGADAARLYIL 303
|
|
| MetG |
COG0143 |
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA ... |
48-628 |
7.52e-12 |
|
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439913 [Multi-domain] Cd Length: 544 Bit Score: 69.37 E-value: 7.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 48 PFATGLPHYGHILAGTIKDIVTRYAHQSGFHVdrRF--GWDCHGLPVEyeidktlgIRGpedvAKMGITEynnqcRAIVM 125
Cdd:COG0143 10 PYANGPPHIGHLYTYIPADILARYQRLRGHDV--LFvtGTDEHGTKIE--------LAA----EKEGITP-----QELVD 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 126 RYSAEWKSTVSRLGrwIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYrgvkvmpfstacntplsnfeshqnykdvqdps 205
Cdd:COG0143 71 RIHAEFKELFEKLG--ISFDNFIRTTSPEHKELVQEIFQRLYDNGDIY-------------------------------- 116
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 206 vfvtfpleedetvslvawtttpwtlpsnlavcvnpemqyvkikdvargrllilmearlsalyklESDYEilerfpGAYlk 285
Cdd:COG0143 117 ----------------------------------------------------------------KGEYE------GWY-- 124
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 286 gkkyrplfdyflkCKENGAFtvLVDNYVkeeEGTgvvhqAPYFGAEDYRvcmdfniirKDSLPVCpvdasgcfttevtdf 365
Cdd:COG0143 125 -------------CPECERF--LPDRYV---EGT-----CPKCGAEDAY---------GDQCENC--------------- 157
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 366 agqyvkdadksiirtlkeqGRLLVATTFTHsyPFCWRSDTPLIYKAVPSWFVRVENMVDQLL----RNNDlcyWVPELVR 441
Cdd:COG0143 158 -------------------GATLEPTELIN--PRSAISGAPPELREEEHYFFRLSKYQDRLLewieENPD---IQPEVRN 213
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 442 EKRfgNWLKDA-RDWTISRNRYWGTPIPlwvsddfeevvcigsvaeleelsGAKisdlhresvDHltipsrcgkgslhri 520
Cdd:COG0143 214 EVL--SWLKEGlQDLSISRDFDWGIPVP-----------------------GDP---------GK--------------- 244
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 521 seVFDCWFE------SGSMPYAQVHYPFENkreFEDAFPAD------FIaeGIDQTRgwFYTLL---VLATAlfGQPPFK 585
Cdd:COG0143 245 --VFYVWFDaligyiSATKGYADDRGLPED---FEKYWPAPdtelvhFI--GKDIIR--FHAIIwpaMLMAA--GLPLPK 313
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 1811715223 586 NVIVNGLVLaSDGQKMSKRKKNYPDPVSIIQKYGADALRLYLI 628
Cdd:COG0143 314 KVFAHGFLT-VEGEKMSKSRGNVIDPDDLLDRYGPDALRYYLL 355
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
48-190 |
3.26e-11 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 66.54 E-value: 3.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 48 PFATGLPHYGHILAGTIKDIVTRYAHQSGFHVdrRF--GWDCHGLPVEYEIDKtLGIrGPEDVakmgiteynnqcraiVM 125
Cdd:pfam09334 8 PYANGPPHLGHLYSYIPADIFARYLRLRGYDV--LFvcGTDEHGTPIELKAEK-EGI-TPEEL---------------VD 68
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1811715223 126 RYSAEWKSTVSRLGrwIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLS 190
Cdd:pfam09334 69 RYHEIHREDFKKFN--ISFDDYGRTTSERHHELVQEFFLKLYENGYIYEKEIEQFYCPSDERFLP 131
|
|
| Anticodon_1 |
pfam08264 |
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA ... |
693-819 |
9.54e-11 |
|
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA synthetases. The domain binds to the anticodon of the tRNA ligase.
Pssm-ID: 400523 [Multi-domain] Cd Length: 141 Bit Score: 60.88 E-value: 9.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 693 DRWILSFMQSLIG--------------------FFETEMGEN----------GMEDCVMALETLFSVLLSLCRLMAPYTP 742
Cdd:pfam08264 1 DRWILSRLNKLIKevteayenyrfntaaqalyeFFWNDLSDWylelikdrlyGEEPDSRAQTTLYEVLETLLRLLAPFMP 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1811715223 743 FLTELMYQNlkvlidpvsvqdkdtLSIHYLMLPrVREELIDKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKEIV 819
Cdd:pfam08264 81 FITEELWQK---------------ESIHLAPWP-EDAELEEAELEEAFELRQEIVQAIRKLRSELKIKKSLPLEVVI 141
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
377-628 |
4.79e-09 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 59.47 E-value: 4.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 377 IIRTLKEQGRLLVATtftHSYPFCWRSDTPL-IYKAVPSWFVRVENMVDQL---LRNNDLCYWvPELVReKRFGNWLKDA 452
Cdd:cd00814 104 FFKKLYENGYIYEGE---YEGLYCVSCERFLpEWREEEHYFFRLSKFQDRLlewLEKNPDFIW-PENAR-NEVLSWLKEG 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 453 -RDWTISR-NRYWGTPIPlwvsdDFEevvcigsvaeleelsgakisdlhresvDHltipsrcgkgslhriseVFDCWFE- 529
Cdd:cd00814 179 lKDLSITRdLFDWGIPVP-----LDP---------------------------GK-----------------VIYVWFDa 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 530 -----SGSMPYAQvhyPFENKREFEDAFPAD--FIaeGIDQTRgwFYTLL---VLATAlfGQPPFKNVIVNGLVLAsDGQ 599
Cdd:cd00814 210 ligyiSATGYYNE---EWGNSWWWKDGWPELvhFI--GKDIIR--FHAIYwpaMLLGA--GLPLPTRIVAHGYLTV-EGK 279
|
250 260
....*....|....*....|....*....
gi 1811715223 600 KMSKRKKNYPDPVSIIQKYGADALRLYLI 628
Cdd:cd00814 280 KMSKSRGNVVDPDDLLERYGADALRYYLL 308
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
540-628 |
3.75e-08 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 57.89 E-value: 3.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 540 YPFENKREFEDAFPADFIAEGIDQTRgwFYT------LLVLatalfGQPPFKNVIVNGLVLAsDGQKMSKRKKNYPDPVS 613
Cdd:PRK12267 241 YGSDDDELFKKFWPADVHLVGKDILR--FHAiywpimLMAL-----GLPLPKKVFAHGWWLM-KDGKMSKSKGNVVDPEE 312
|
90
....*....|....*
gi 1811715223 614 IIQKYGADALRLYLI 628
Cdd:PRK12267 313 LVDRYGLDALRYYLL 327
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
398-628 |
2.35e-07 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 54.89 E-value: 2.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 398 PFCWRSDTPLIYKAVPSWFVRVENMVDQLL---RNNdlcywvPELV----REKRFGNWLKD-ARDWTISRNRY-WGTPIP 468
Cdd:PRK11893 142 YRCPPTGAPVEWVEEESYFFRLSKYQDKLLelyEAN------PDFIqpasRRNEVISFVKSgLKDLSISRTNFdWGIPVP 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 469 lwvSDDfeevvcigsvaeleelsgakisdlhresvdhltipsrcgkgsLHRISEVFD--CWFESGSM-PYAQVhypfENK 545
Cdd:PRK11893 216 ---GDP------------------------------------------KHVIYVWFDalTNYLTALGyPDDEE----LLA 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 546 REFEDAFPAD--FIaeGIDQTR----GWfytlLVLATALfGQPPFKNVIVNG-LVLasDGQKMSKRKKNYPDPVSIIQKY 618
Cdd:PRK11893 247 ELFNKYWPADvhLI--GKDILRfhavYW----PAFLMAA-GLPLPKRVFAHGfLTL--DGEKMSKSLGNVIDPFDLVDEY 317
|
250
....*....|
gi 1811715223 619 GADALRLYLI 628
Cdd:PRK11893 318 GVDAVRYFLL 327
|
|
| Anticodon_Ia_Val |
cd07962 |
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA ... |
657-752 |
2.28e-06 |
|
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA synthetases (ValRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. ValRS catalyzes the transfer of valine to the 3'-end of its tRNA.
Pssm-ID: 153416 [Multi-domain] Cd Length: 135 Bit Score: 48.32 E-value: 2.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 657 YNAYRFLIQNvlrlqkeeeIEFLYNENTVRESPNITDRWILSFMQSLIG----------FFE------------------ 708
Cdd:cd07962 17 WNAARFVLMN---------LEDDDEPEEDPESLSLADRWILSRLNKTVEevtealenyrFSEaatalyeffwndfcdwyl 87
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1811715223 709 ----TEMGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNL 752
Cdd:cd07962 88 elvkPRLYGEDEEEKKAARATLYYVLETILRLLHPFMPFITEELWQRL 135
|
|
| CysRS_core |
cd00672 |
catalytic core domain of cysteinyl tRNA synthetase; Cysteinyl tRNA synthetase (CysRS) ... |
572-630 |
5.93e-05 |
|
catalytic core domain of cysteinyl tRNA synthetase; Cysteinyl tRNA synthetase (CysRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173899 [Multi-domain] Cd Length: 213 Bit Score: 45.65 E-value: 5.93e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1811715223 572 LVLATALFGQPPFKNVIVNGLVLAsDGQKMSKRKKNYPDPVSIIQKYGADALRLYLINS 630
Cdd:cd00672 147 IAQSEAATGKPFARYWLHTGHLTI-DGEKMSKSLGNFITVRDALKKYDPEVLRLALLSS 204
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
48-174 |
2.97e-04 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 45.14 E-value: 2.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 48 PFATGLPHYGHILAGTIKDIVTRYAHQSGFHVdrRF--GWDCHGLPVEyeidktlgIRGpedvAKMGITEynnqcRAIVM 125
Cdd:PRK00133 11 PYANGPIHLGHLVEYIQADIWVRYQRMRGHEV--LFvcADDAHGTPIM--------LKA----EKEGITP-----EELIA 71
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1811715223 126 RYSAEWKSTVSRLGrwIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYR 174
Cdd:PRK00133 72 RYHAEHKRDFAGFG--ISFDNYGSTHSEENRELAQEIYLKLKENGYIYE 118
|
|
| tRNA-synt_1e |
pfam01406 |
tRNA synthetases class I (C) catalytic domain; This family includes only cysteinyl tRNA ... |
576-650 |
4.27e-04 |
|
tRNA synthetases class I (C) catalytic domain; This family includes only cysteinyl tRNA synthetases.
Pssm-ID: 396128 [Multi-domain] Cd Length: 301 Bit Score: 43.90 E-value: 4.27e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1811715223 576 TALFGQPPFKNVIVNGLVLAsDGQKMSKRKKNYPDPVSIIQKYGADALRLYLI----NSPvvraenLRFKEEGVRDVLK 650
Cdd:pfam01406 230 EAAFDKQLANYWLHNGHVMI-DGEKMSKSLGNFFTIRDVLKRYDPEILRYFLLsvhyRSP------LDFSEELLEQAKS 301
|
|
| Anticodon_Ia_Leu_AEc |
cd07959 |
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This ... |
668-752 |
8.33e-04 |
|
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes archaeal and eukaryotic cytoplasmic members. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153413 [Multi-domain] Cd Length: 117 Bit Score: 40.27 E-value: 8.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1811715223 668 LRLQKEEE-IEFLYNENTVRESPNITDRWILSFMQSLI------------------GFFE--------TEMGENGMEDCV 720
Cdd:cd07959 11 LRLERFYElAEELIETEGELEELTFIDRWLLSRLNRLIketteayenmqfrealkeGLYElqndldwyRERGGAGMNKDL 90
|
90 100 110
....*....|....*....|....*....|..
gi 1811715223 721 maletLFSVLLSLCRLMAPYTPFLTELMYQNL 752
Cdd:cd07959 91 -----LRRFIEVWTRLLAPFAPHLAEEIWHEL 117
|
|
| Anticodon_Ia_Ile_BEm |
cd07960 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; ... |
725-796 |
1.52e-03 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial and eukaryotic mitochondrial members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153414 [Multi-domain] Cd Length: 180 Bit Score: 40.97 E-value: 1.52e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1811715223 725 TLFSVLLSLCRLMAPYTPFLTELMYQNLKVLIDPVSVqdkdtlsiHYLMLPRVREELIDKKTESAVSQMQSV 796
Cdd:cd07960 112 VLYHILDALLKLLAPILPFTAEEVWEHLPGEKKEESV--------FLEDWPELPEEWKDEELEEKWEKLLAL 175
|
|
| |
