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Conserved domains on  [gi|1829653630|ref|NP_001366535|]
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dipeptidyl peptidase 4 isoform 4 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 108-460 8.50e-116

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


:

Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 353.16  E-value: 8.50e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 108 SPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITW 187
Cdd:pfam00930   1 SPDGKYLLLATNYTKNWRHSYTADYYIYDLETNRVEPLPPGEGKIQDAKWSPDGDRLAFVRDNNLYVRELATGKEIQITS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 188 TGkEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQyPKTVRVPYPKAGAVNPTVK 267
Cdd:pfam00930  81 DG-SDGIFNGVADWVYEEEVLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPYYTDEGPG-PEVREIKYPKAGAPNPTVE 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 268 FFVVNTDSLSSVTnatsiqITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNClvarqhiE 347
Cdd:pfam00930 159 LFVYDLASGKTVE------VVPPDDLSDADYYITRVKWVPDGKLLVQWLNRDQNRLKVVLCDAETGRTVVIL-------E 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 348 MSTTGWVgrFRPSEPHFTL-DGNSFYKiISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEA--LTSD----------- 413
Cdd:pfam00930 226 ETSDGWV--ELHQDPHFIKrDGSGFLW-ISERDGYNHLYLYDLDGKSPIQLTSGNWEVTSILGvdETRDlvyftatedsp 302

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1829653630 414 -----YLIQLSDYTKVTCLSCELNPErcqYYSVSFSKEAKYYQLRCSGPGLP 460
Cdd:pfam00930 303 terhlYSVSLDSGGEPTCLTDDSGDH---DYSASFSPNGSYYVLTYSGPDTP 351
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
541-745 8.12e-65

Prolyl oligopeptidase family;


:

Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 214.40  E-value: 8.12e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 541 FRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSM 620
Cdd:pfam00326   1 PSFSWNAQLLADRGYVVAIANGRGSGGYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQGYTDPDRLAIWGGSYGGYLTGA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 621 VLGSGSGVFKCGIAVAPVSRWEYYDS----VYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQ-VEYLLIHGTADDNVHF 695
Cdd:pfam00326  81 ALNQRPDLFKAAVAHVPVVDWLAYMSdtslPFTERYMEWGNPWDNEEGYDYLSPYSPADNVKVyPPLLLIHGLLDDRVPP 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1829653630 696 QQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCF 745
Cdd:pfam00326 161 WQSLKLVAALQRKGVPFLLLIFPDEGHGIGKPRNKVEEYARELAFLLEYL 210
DPPIV_rep pfam18811
Dipeptidyl peptidase IV (DPP IV) low complexity region; Dipeptidyl peptidase IV includes an ...
 38-58 2.81e-04

Dipeptidyl peptidase IV (DPP IV) low complexity region; Dipeptidyl peptidase IV includes an helical N-terminal region, the pfam00930 domain and the pfam00326 domain, comprising the active site. This Pfam entry represents a sequence that can be repeated in the low complexity region between the helical N-terminus and the DPPIV_N domain.


:

Pssm-ID: 465875  Cd Length: 21  Bit Score: 38.62  E-value: 2.81e-04
                          10        20
                  ....*....|....*....|.
gi 1829653630  38 DSRKTYTLTDYLKNTYRLKLY 58
Cdd:pfam18811   1 DSRRTFTLEDYLNNTFRYKSY 21
 
Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 108-460 8.50e-116

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 353.16  E-value: 8.50e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 108 SPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITW 187
Cdd:pfam00930   1 SPDGKYLLLATNYTKNWRHSYTADYYIYDLETNRVEPLPPGEGKIQDAKWSPDGDRLAFVRDNNLYVRELATGKEIQITS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 188 TGkEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQyPKTVRVPYPKAGAVNPTVK 267
Cdd:pfam00930  81 DG-SDGIFNGVADWVYEEEVLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPYYTDEGPG-PEVREIKYPKAGAPNPTVE 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 268 FFVVNTDSLSSVTnatsiqITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNClvarqhiE 347
Cdd:pfam00930 159 LFVYDLASGKTVE------VVPPDDLSDADYYITRVKWVPDGKLLVQWLNRDQNRLKVVLCDAETGRTVVIL-------E 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 348 MSTTGWVgrFRPSEPHFTL-DGNSFYKiISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEA--LTSD----------- 413
Cdd:pfam00930 226 ETSDGWV--ELHQDPHFIKrDGSGFLW-ISERDGYNHLYLYDLDGKSPIQLTSGNWEVTSILGvdETRDlvyftatedsp 302

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1829653630 414 -----YLIQLSDYTKVTCLSCELNPErcqYYSVSFSKEAKYYQLRCSGPGLP 460
Cdd:pfam00930 303 terhlYSVSLDSGGEPTCLTDDSGDH---DYSASFSPNGSYYVLTYSGPDTP 351
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
541-745 8.12e-65

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 214.40  E-value: 8.12e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 541 FRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSM 620
Cdd:pfam00326   1 PSFSWNAQLLADRGYVVAIANGRGSGGYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQGYTDPDRLAIWGGSYGGYLTGA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 621 VLGSGSGVFKCGIAVAPVSRWEYYDS----VYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQ-VEYLLIHGTADDNVHF 695
Cdd:pfam00326  81 ALNQRPDLFKAAVAHVPVVDWLAYMSdtslPFTERYMEWGNPWDNEEGYDYLSPYSPADNVKVyPPLLLIHGLLDDRVPP 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1829653630 696 QQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCF 745
Cdd:pfam00326 161 WQSLKLVAALQRKGVPFLLLIFPDEGHGIGKPRNKVEEYARELAFLLEYL 210
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
504-745 2.88e-50

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 175.59  E-value: 2.88e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 504 TKFWYQMILPPhfdKSKKYPLLLDVYAGPCSQkaDTVFRLnWATYLAStENIIVASFDGRGSGYQGdkimhainRRLGTF 583
Cdd:COG1506     8 TTLPGWLYLPA---DGKKYPVVVYVHGGPGSR--DDSFLP-LAQALAS-RGYAVLAPDYRGYGESA--------GDWGGD 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 584 EVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSV---YTERYMGlpTPED 660
Cdd:COG1506    73 EVDDVLAAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRSYYGTtreYTERLMG--GPWE 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 661 NLDHYRNSTVMSRAENFKqVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIaSSTAHQHIYTHMSHF 740
Cdd:COG1506   151 DPEAYAARSPLAYADKLK-TPLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGF-SGAGAPDYLERILDF 228


                  ....*
gi 1829653630 741 IKQCF 745
Cdd:COG1506   229 LDRHL 233
WD40 COG2319
WD40 repeat [General function prediction only];
94-231 4.92e-05

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 46.44  E-value: 4.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630  94 TFDEFGHSINDYSISPDGQFILleynyvkqwrhsyTASYD----IYDLNKRQLITEerIPNNTQWVT---WSPVGHKLAY 166
Cdd:COG2319   115 TLTGHTGAVRSVAFSPDGKTLA-------------SGSADgtvrLWDLATGKLLRT--LTGHSGAVTsvaFSPDGKLLAS 179

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1829653630 167 VWNNDIyVKIepnlpsyritW---TGKEDIIYNGITDWVYeeevfsaysALWWSPNGTFLAYAQFNDT 231
Cdd:COG2319   180 GSDDGT-VRL----------WdlaTGKLLRTLTGHTGAVR---------SVAFSPDGKLLASGSADGT 227
DPPIV_rep pfam18811
Dipeptidyl peptidase IV (DPP IV) low complexity region; Dipeptidyl peptidase IV includes an ...
 38-58 2.81e-04

Dipeptidyl peptidase IV (DPP IV) low complexity region; Dipeptidyl peptidase IV includes an helical N-terminal region, the pfam00930 domain and the pfam00326 domain, comprising the active site. This Pfam entry represents a sequence that can be repeated in the low complexity region between the helical N-terminus and the DPPIV_N domain.


Pssm-ID: 465875  Cd Length: 21  Bit Score: 38.62  E-value: 2.81e-04
                          10        20
                  ....*....|....*....|.
gi 1829653630  38 DSRKTYTLTDYLKNTYRLKLY 58
Cdd:pfam18811   1 DSRRTFTLEDYLNNTFRYKSY 21
 
Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 108-460 8.50e-116

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 353.16  E-value: 8.50e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 108 SPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITW 187
Cdd:pfam00930   1 SPDGKYLLLATNYTKNWRHSYTADYYIYDLETNRVEPLPPGEGKIQDAKWSPDGDRLAFVRDNNLYVRELATGKEIQITS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 188 TGkEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQyPKTVRVPYPKAGAVNPTVK 267
Cdd:pfam00930  81 DG-SDGIFNGVADWVYEEEVLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPYYTDEGPG-PEVREIKYPKAGAPNPTVE 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 268 FFVVNTDSLSSVTnatsiqITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNClvarqhiE 347
Cdd:pfam00930 159 LFVYDLASGKTVE------VVPPDDLSDADYYITRVKWVPDGKLLVQWLNRDQNRLKVVLCDAETGRTVVIL-------E 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 348 MSTTGWVgrFRPSEPHFTL-DGNSFYKiISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEA--LTSD----------- 413
Cdd:pfam00930 226 ETSDGWV--ELHQDPHFIKrDGSGFLW-ISERDGYNHLYLYDLDGKSPIQLTSGNWEVTSILGvdETRDlvyftatedsp 302

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1829653630 414 -----YLIQLSDYTKVTCLSCELNPErcqYYSVSFSKEAKYYQLRCSGPGLP 460
Cdd:pfam00930 303 terhlYSVSLDSGGEPTCLTDDSGDH---DYSASFSPNGSYYVLTYSGPDTP 351
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
541-745 8.12e-65

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 214.40  E-value: 8.12e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 541 FRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSM 620
Cdd:pfam00326   1 PSFSWNAQLLADRGYVVAIANGRGSGGYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQGYTDPDRLAIWGGSYGGYLTGA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 621 VLGSGSGVFKCGIAVAPVSRWEYYDS----VYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQ-VEYLLIHGTADDNVHF 695
Cdd:pfam00326  81 ALNQRPDLFKAAVAHVPVVDWLAYMSdtslPFTERYMEWGNPWDNEEGYDYLSPYSPADNVKVyPPLLLIHGLLDDRVPP 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1829653630 696 QQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCF 745
Cdd:pfam00326 161 WQSLKLVAALQRKGVPFLLLIFPDEGHGIGKPRNKVEEYARELAFLLEYL 210
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
504-745 2.88e-50

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 175.59  E-value: 2.88e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 504 TKFWYQMILPPhfdKSKKYPLLLDVYAGPCSQkaDTVFRLnWATYLAStENIIVASFDGRGSGYQGdkimhainRRLGTF 583
Cdd:COG1506     8 TTLPGWLYLPA---DGKKYPVVVYVHGGPGSR--DDSFLP-LAQALAS-RGYAVLAPDYRGYGESA--------GDWGGD 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 584 EVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSV---YTERYMGlpTPED 660
Cdd:COG1506    73 EVDDVLAAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRSYYGTtreYTERLMG--GPWE 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 661 NLDHYRNSTVMSRAENFKqVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIaSSTAHQHIYTHMSHF 740
Cdd:COG1506   151 DPEAYAARSPLAYADKLK-TPLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGF-SGAGAPDYLERILDF 228


                  ....*
gi 1829653630 741 IKQCF 745
Cdd:COG1506   229 LDRHL 233
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
548-723 7.41e-11

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 62.68  E-value: 7.41e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 548 YLAstenIIVASFDGRGSGYQGDKIMHAINRrLGTFEVEDQIEAARQF-SKMGFVDNKRIAIWGWSYGGYVTsMVLGSGS 626
Cdd:COG0412    57 YVV----LAPDLYGRGGPGDDPDEARALMGA-LDPELLAADLRAALDWlKAQPEVDAGRVGVVGFCFGGGLA-LLAAARG 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 627 GVFKCGIAvapvsrweYYdsvyterymGLPTPEDNLDHYRNSTVmsraenfkqvEYLLIHGTADDNVHFQQSAQISKALV 706
Cdd:COG0412   131 PDLAAAVS--------FY---------GGLPADDLLDLAARIKA----------PVLLLYGEKDPLVPPEQVAALEAALA 183

                         170
                  ....*....|....*..
gi 1829653630 707 DVGVDFQAMWYTDEDHG 723
Cdd:COG0412   184 AAGVDVELHVYPGAGHG 200
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 507-704 6.45e-08

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 54.54  E-value: 6.45e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 507 WYqmiLPPhfDKSKKYPLLldVYAGP-CSQKADtvfRLNWATYLAStENIIVASFDGRGSGY-QGDKimhainRRLGTFE 584
Cdd:COG1073    27 LY---LPA--GASKKYPAV--VVAHGnGGVKEQ---RALYAQRLAE-LGFNVLAFDYRGYGEsEGEP------REEGSPE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 585 VEDqIEAARQF-SKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVfKCGIAVAPVS--------RWEYYDSVYTERYMGL 655
Cdd:COG1073    90 RRD-ARAAVDYlRTLPGVDPERIGLLGISLGGGYALNAAATDPRV-KAVILDSPFTsledlaaqRAKEARGAYLPGVPYL 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1829653630 656 PTPEdnldhyRNSTVMSRAENFKQVEY-----LLIHGTADDNVHFQQSAQISKA 704
Cdd:COG1073   168 PNVR------LASLLNDEFDPLAKIEKisrplLFIHGEKDEAVPFYMSEDLYEA 215
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
545-743 3.20e-06

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 48.84  E-value: 3.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 545 WATYLAStENIIVASFDGRGSGYQGdkimhainRRLGTFE-VEDQIEAARQFskMGFV---DNKRIAIWGWSYGGYVTSM 620
Cdd:COG2267    47 LAEALAA-AGYAVLAFDLRGHGRSD--------GPRGHVDsFDDYVDDLRAA--LDALrarPGLPVVLLGHSMGGLIALL 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 621 VLGSGSGVFKCGIAVAPvsrweyydsvyteRYMGLPTPEDNLDHYRNSTVMSRAENFKQ-VeyLLIHGTADDNVHFQQSA 699
Cdd:COG2267   116 YAARYPDRVAGLVLLAP-------------AYRADPLLGPSARWLRALRLAEALARIDVpV--LVLHGGADRVVPPEAAR 180

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1829653630 700 QISKALVDvgvDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQ 743
Cdd:COG2267   181 RLAARLSP---DVELVLLPGARHELLNEPAREEVLAAILAWLER 221
WD40 COG2319
WD40 repeat [General function prediction only];
94-231 4.92e-05

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 46.44  E-value: 4.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630  94 TFDEFGHSINDYSISPDGQFILleynyvkqwrhsyTASYD----IYDLNKRQLITEerIPNNTQWVT---WSPVGHKLAY 166
Cdd:COG2319   115 TLTGHTGAVRSVAFSPDGKTLA-------------SGSADgtvrLWDLATGKLLRT--LTGHSGAVTsvaFSPDGKLLAS 179

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1829653630 167 VWNNDIyVKIepnlpsyritW---TGKEDIIYNGITDWVYeeevfsaysALWWSPNGTFLAYAQFNDT 231
Cdd:COG2319   180 GSDDGT-VRL----------WdlaTGKLLRTLTGHTGAVR---------SVAFSPDGKLLASGSADGT 227
WD40 COG2319
WD40 repeat [General function prediction only];
94-231 4.96e-05

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 46.44  E-value: 4.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630  94 TFDEFGHSINDYSISPDGQFILleynyvkqwrhsyTASYD----IYDLNKRQLITeeRIPNNTQWVT---WSPVGHKLA- 165
Cdd:COG2319   199 TLTGHTGAVRSVAFSPDGKLLA-------------SGSADgtvrLWDLATGKLLR--TLTGHSGSVRsvaFSPDGRLLAs 263

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1829653630 166 -------YVWNNDiyvkiepnlpsyritwTGKEDIIYNGITDWVYeeevfsaysALWWSPNGTFLAYAQFNDT 231
Cdd:COG2319   264 gsadgtvRLWDLA----------------TGELLRTLTGHSGGVN---------SVAFSPDGKLLASGSDDGT 311
WD40 COG2319
WD40 repeat [General function prediction only];
94-226 8.95e-05

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 45.67  E-value: 8.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630  94 TFDEFGHSINDYSISPDGQFILleynyvkqwrhsyTASYD----IYDLNKRQLITEERIPNNTQW-VTWSPVGHKLA--- 165
Cdd:COG2319   283 TLTGHSGGVNSVAFSPDGKLLA-------------SGSDDgtvrLWDLATGKLLRTLTGHTGAVRsVAFSPDGKTLAsgs 349

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1829653630 166 -----YVWNNDiyvkiepnlpsyritwTGKEDIIYNGITDWVYeeevfsaysALWWSPNGTFLAYA 226
Cdd:COG2319   350 ddgtvRLWDLA----------------TGELLRTLTGHTGAVT---------SVAFSPDGRTLASG 390
WD40 COG2319
WD40 repeat [General function prediction only];
99-224 9.77e-05

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 45.29  E-value: 9.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630  99 GHS--INDYSISPDGQFILleynyvkqwrhsyTASYD----IYDLNKRQLITeeRIPNNTQWVT---WSPVGHKLAyVWN 169
Cdd:COG2319   160 GHSgaVTSVAFSPDGKLLA-------------SGSDDgtvrLWDLATGKLLR--TLTGHTGAVRsvaFSPDGKLLA-SGS 223

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1829653630 170 NDIYVKIepnlpsyritW---TGKEDIIYNGITDWVYeeevfsaysALWWSPNGTFLA 224
Cdd:COG2319   224 ADGTVRL----------WdlaTGKLLRTLTGHSGSVR---------SVAFSPDGRLLA 262
DPPIV_rep pfam18811
Dipeptidyl peptidase IV (DPP IV) low complexity region; Dipeptidyl peptidase IV includes an ...
 38-58 2.81e-04

Dipeptidyl peptidase IV (DPP IV) low complexity region; Dipeptidyl peptidase IV includes an helical N-terminal region, the pfam00930 domain and the pfam00326 domain, comprising the active site. This Pfam entry represents a sequence that can be repeated in the low complexity region between the helical N-terminus and the DPPIV_N domain.


Pssm-ID: 465875  Cd Length: 21  Bit Score: 38.62  E-value: 2.81e-04
                          10        20
                  ....*....|....*....|.
gi 1829653630  38 DSRKTYTLTDYLKNTYRLKLY 58
Cdd:pfam18811   1 DSRRTFTLEDYLNNTFRYKSY 21
YpfH COG0400
Predicted esterase [General function prediction only];
546-746 5.20e-04

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 41.82  E-value: 5.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 546 ATYLAStENIIVASFDGRGSGYQGdkiMHA---INRRLGTFEVEDQIEAARQFskMGFVD---------NKRIAIWGWSY 613
Cdd:COG0400    25 APELAL-PGAAVLAPRAPVPEGPG---GRAwfdLSFLEGREDEEGLAAAAEAL--AAFIDelearygidPERIVLAGFSQ 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 614 GGYVTSMVLGSGSGVFKCGIAVAPvsrweyydsvyterymGLPTPEDNLDhyrnstvmsRAENFKQVEYLLIHGTADDNV 693
Cdd:COG0400    99 GAAMALSLALRRPELLAGVVALSG----------------YLPGEEALPA---------PEAALAGTPVFLAHGTQDPVI 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1829653630 694 HFQQSAQISKALVDVGVDFQAMWYtDEDHGIasstaHQHIYTHMSHFIKQCFS 746
Cdd:COG0400   154 PVERAREAAEALEAAGADVTYREY-PGGHEI-----SPEELADARAWLAERLA 200
WD40 COG2319
WD40 repeat [General function prediction only];
94-226 5.89e-04

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 42.98  E-value: 5.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630  94 TFDEFGHSINDYSISPDGQFILleynyvkqwrhsyTASYD----IYDLNKRQLITeeRIPNNTQWVT---WSPVGHKLAy 166
Cdd:COG2319   241 TLTGHSGSVRSVAFSPDGRLLA-------------SGSADgtvrLWDLATGELLR--TLTGHSGGVNsvaFSPDGKLLA- 304

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1829653630 167 VWNNDIYVKIepnlpsyritW---TGKEDIIYNGITDWVYeeevfsaysALWWSPNGTFLAYA 226
Cdd:COG2319   305 SGSDDGTVRL----------WdlaTGKLLRTLTGHTGAVR---------SVAFSPDGKTLASG 348
LpqC COG3509
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ...
 508-701 6.45e-04

Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];


Pssm-ID: 442732 [Multi-domain]  Cd Length: 284  Bit Score: 42.30  E-value: 6.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 508 YQMILPPHFDKSKKYPLLLdVYAGpCSQKADTVFRL-NWATyLASTENIIVASFDGRGSGYQG--DKIMHAINRRlGTFE 584
Cdd:COG3509    39 YRLYVPAGYDGGAPLPLVV-ALHG-CGGSAADFAAGtGLNA-LADREGFIVVYPEGTGRAPGRcwNWFDGRDQRR-GRDD 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1829653630 585 VE--DQI--EAARQFSkmgfVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKcgiAVAPVSrweyydsvyterymGLPtped 660
Cdd:COG3509   115 VAfiAALvdDLAARYG----IDPKRVYVTGLSAGGAMAYRLACEYPDVFA---AVAPVA--------------GLP---- 169

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1829653630 661 nldhYRNSTVMSRAENfKQVEYLLIHGTADDNVHFQQSAQI 701
Cdd:COG3509   170 ----YGAASDAACAPG-RPVPVLVIHGTADPTVPYAGAEET 205
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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