NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1867163670|ref|NP_001371953|]
View 

ARL14 effector protein-like isoform 2 [Homo sapiens]

Protein Classification

ARF7EP_C domain-containing protein( domain architecture ID 10633122)

ARF7EP_C domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ARF7EP_C pfam14949
ARF7 effector protein C-terminus; This family represents the C-terminus of the ARF7 effector ...
 1-72 3.34e-30

ARF7 effector protein C-terminus; This family represents the C-terminus of the ARF7 effector protein (ARF7EP). ARF7EP interacts with ADP-ribosylation factor-like protein 14 and unconventional myosin-Ie and through this interaction controls movement of MHC-II-containing vesicles along the actin cytoskeleton in dendritic cells. It contains a conserved CXCXXXXCXXCXXXCXXCXXXXCXXXCXC motif in it's C-terminal half.


:

Pssm-ID: 464395  Cd Length: 102  Bit Score: 102.35  E-value: 3.34e-30
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1867163670   1 MSKMNEYFsTKYKIMRKYDKSGRLICNDADLCDCLEKNCLGCFYPCPKCNSNKCGPECRCNRRWVYDAIVTE 72
Cdd:pfam14949  32 ARKVNKRP-NRNKKSKHYDENGKLISNGKDLCDCLDEECPGCHYPCPKCGSRKCGPECRCNRKWMYESIEVE 102
 
Name Accession Description Interval E-value
ARF7EP_C pfam14949
ARF7 effector protein C-terminus; This family represents the C-terminus of the ARF7 effector ...
 1-72 3.34e-30

ARF7 effector protein C-terminus; This family represents the C-terminus of the ARF7 effector protein (ARF7EP). ARF7EP interacts with ADP-ribosylation factor-like protein 14 and unconventional myosin-Ie and through this interaction controls movement of MHC-II-containing vesicles along the actin cytoskeleton in dendritic cells. It contains a conserved CXCXXXXCXXCXXXCXXCXXXXCXXXCXC motif in it's C-terminal half.


Pssm-ID: 464395  Cd Length: 102  Bit Score: 102.35  E-value: 3.34e-30
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1867163670   1 MSKMNEYFsTKYKIMRKYDKSGRLICNDADLCDCLEKNCLGCFYPCPKCNSNKCGPECRCNRRWVYDAIVTE 72
Cdd:pfam14949  32 ARKVNKRP-NRNKKSKHYDENGKLISNGKDLCDCLDEECPGCHYPCPKCGSRKCGPECRCNRKWMYESIEVE 102
 
Name Accession Description Interval E-value
ARF7EP_C pfam14949
ARF7 effector protein C-terminus; This family represents the C-terminus of the ARF7 effector ...
 1-72 3.34e-30

ARF7 effector protein C-terminus; This family represents the C-terminus of the ARF7 effector protein (ARF7EP). ARF7EP interacts with ADP-ribosylation factor-like protein 14 and unconventional myosin-Ie and through this interaction controls movement of MHC-II-containing vesicles along the actin cytoskeleton in dendritic cells. It contains a conserved CXCXXXXCXXCXXXCXXCXXXXCXXXCXC motif in it's C-terminal half.


Pssm-ID: 464395  Cd Length: 102  Bit Score: 102.35  E-value: 3.34e-30
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1867163670   1 MSKMNEYFsTKYKIMRKYDKSGRLICNDADLCDCLEKNCLGCFYPCPKCNSNKCGPECRCNRRWVYDAIVTE 72
Cdd:pfam14949  32 ARKVNKRP-NRNKKSKHYDENGKLISNGKDLCDCLDEECPGCHYPCPKCGSRKCGPECRCNRKWMYESIEVE 102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH