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small conductance calcium-activated potassium channel protein 1 isoform 2 [Homo sapiens]
SK_channel and CaMBD domain-containing protein( domain architecture ID 10507664)
protein containing domains SK_channel, Ion_trans_2, and CaMBD
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
SK_channel | pfam03530 | Calcium-activated SK potassium channel; |
93-202 | 3.51e-63 | |||
Calcium-activated SK potassium channel; : Pssm-ID: 460958 Cd Length: 111 Bit Score: 202.06 E-value: 3.51e-63
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CaMBD | smart01053 | Calmodulin binding domain; Small-conductance Ca2+-activated K+ channels (SK channels) are ... |
387-464 | 1.13e-40 | |||
Calmodulin binding domain; Small-conductance Ca2+-activated K+ channels (SK channels) are independent of voltage and gated solely by intracellular Ca2+. These membrane channels are heteromeric complexes that comprise pore-forming alpha-subunits and the Ca2+-binding protein calmodulin (CaM). CaM binds to the SK channel through this the CaM-binding domain (CaMBD), which is located in an intracellular region of the alpha-subunit immediately carboxy-terminal to the pore. Channel opening is triggered when Ca2+ binds the EF hands in the N-lobe of CaM. The structure of this domain complexed with CaM is known. This domain forms an elongated dimer with a CaM molecule bound at each end; each CaM wraps around three alpha-helices, two from one CaMBD subunit and one from the other. : Pssm-ID: 198121 Cd Length: 76 Bit Score: 141.40 E-value: 1.13e-40
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Ion_trans_2 | pfam07885 | Ion channel; This family includes the two membrane helix type ion channels found in bacteria. |
291-373 | 6.84e-14 | |||
Ion channel; This family includes the two membrane helix type ion channels found in bacteria. : Pssm-ID: 462301 [Multi-domain] Cd Length: 78 Bit Score: 66.91 E-value: 6.84e-14
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EnvC super family | cl34844 | Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
420-510 | 1.32e-03 | |||
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]; The actual alignment was detected with superfamily member COG4942: Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 1.32e-03
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Name | Accession | Description | Interval | E-value | |||
SK_channel | pfam03530 | Calcium-activated SK potassium channel; |
93-202 | 3.51e-63 | |||
Calcium-activated SK potassium channel; Pssm-ID: 460958 Cd Length: 111 Bit Score: 202.06 E-value: 3.51e-63
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CaMBD | smart01053 | Calmodulin binding domain; Small-conductance Ca2+-activated K+ channels (SK channels) are ... |
387-464 | 1.13e-40 | |||
Calmodulin binding domain; Small-conductance Ca2+-activated K+ channels (SK channels) are independent of voltage and gated solely by intracellular Ca2+. These membrane channels are heteromeric complexes that comprise pore-forming alpha-subunits and the Ca2+-binding protein calmodulin (CaM). CaM binds to the SK channel through this the CaM-binding domain (CaMBD), which is located in an intracellular region of the alpha-subunit immediately carboxy-terminal to the pore. Channel opening is triggered when Ca2+ binds the EF hands in the N-lobe of CaM. The structure of this domain complexed with CaM is known. This domain forms an elongated dimer with a CaM molecule bound at each end; each CaM wraps around three alpha-helices, two from one CaMBD subunit and one from the other. Pssm-ID: 198121 Cd Length: 76 Bit Score: 141.40 E-value: 1.13e-40
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CaMBD | pfam02888 | Calmodulin binding domain; Small-conductance Ca2+-activated K+ channels (SK channels) are ... |
387-464 | 3.69e-40 | |||
Calmodulin binding domain; Small-conductance Ca2+-activated K+ channels (SK channels) are independent of voltage and gated solely by intracellular Ca2+. These membrane channels are heteromeric complexes that comprise pore-forming alpha-subunits and the Ca2+-binding protein calmodulin (CaM). CaM binds to the SK channel through this the CaM-binding domain (CaMBD), which is located in an intracellular region of the alpha-subunit immediately carboxy-terminal to the pore. Channel opening is triggered when Ca2+ binds the EF hands in the N-lobe of CaM. The structure of this domain complexed with CaM is known. This domain forms an elongated dimer with a CaM molecule bound at each end; each CaM wraps around three alpha-helices, two from one CaMBD subunit and one from the other. Pssm-ID: 460739 Cd Length: 75 Bit Score: 140.11 E-value: 3.69e-40
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Ion_trans_2 | pfam07885 | Ion channel; This family includes the two membrane helix type ion channels found in bacteria. |
291-373 | 6.84e-14 | |||
Ion channel; This family includes the two membrane helix type ion channels found in bacteria. Pssm-ID: 462301 [Multi-domain] Cd Length: 78 Bit Score: 66.91 E-value: 6.84e-14
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GumC | COG3206 | Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
387-510 | 9.10e-04 | |||
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.93 E-value: 9.10e-04
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EnvC | COG4942 | Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
420-510 | 1.32e-03 | |||
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]; Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 1.32e-03
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Name | Accession | Description | Interval | E-value | |||
SK_channel | pfam03530 | Calcium-activated SK potassium channel; |
93-202 | 3.51e-63 | |||
Calcium-activated SK potassium channel; Pssm-ID: 460958 Cd Length: 111 Bit Score: 202.06 E-value: 3.51e-63
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CaMBD | smart01053 | Calmodulin binding domain; Small-conductance Ca2+-activated K+ channels (SK channels) are ... |
387-464 | 1.13e-40 | |||
Calmodulin binding domain; Small-conductance Ca2+-activated K+ channels (SK channels) are independent of voltage and gated solely by intracellular Ca2+. These membrane channels are heteromeric complexes that comprise pore-forming alpha-subunits and the Ca2+-binding protein calmodulin (CaM). CaM binds to the SK channel through this the CaM-binding domain (CaMBD), which is located in an intracellular region of the alpha-subunit immediately carboxy-terminal to the pore. Channel opening is triggered when Ca2+ binds the EF hands in the N-lobe of CaM. The structure of this domain complexed with CaM is known. This domain forms an elongated dimer with a CaM molecule bound at each end; each CaM wraps around three alpha-helices, two from one CaMBD subunit and one from the other. Pssm-ID: 198121 Cd Length: 76 Bit Score: 141.40 E-value: 1.13e-40
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CaMBD | pfam02888 | Calmodulin binding domain; Small-conductance Ca2+-activated K+ channels (SK channels) are ... |
387-464 | 3.69e-40 | |||
Calmodulin binding domain; Small-conductance Ca2+-activated K+ channels (SK channels) are independent of voltage and gated solely by intracellular Ca2+. These membrane channels are heteromeric complexes that comprise pore-forming alpha-subunits and the Ca2+-binding protein calmodulin (CaM). CaM binds to the SK channel through this the CaM-binding domain (CaMBD), which is located in an intracellular region of the alpha-subunit immediately carboxy-terminal to the pore. Channel opening is triggered when Ca2+ binds the EF hands in the N-lobe of CaM. The structure of this domain complexed with CaM is known. This domain forms an elongated dimer with a CaM molecule bound at each end; each CaM wraps around three alpha-helices, two from one CaMBD subunit and one from the other. Pssm-ID: 460739 Cd Length: 75 Bit Score: 140.11 E-value: 3.69e-40
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Ion_trans_2 | pfam07885 | Ion channel; This family includes the two membrane helix type ion channels found in bacteria. |
291-373 | 6.84e-14 | |||
Ion channel; This family includes the two membrane helix type ion channels found in bacteria. Pssm-ID: 462301 [Multi-domain] Cd Length: 78 Bit Score: 66.91 E-value: 6.84e-14
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GumC | COG3206 | Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
387-510 | 9.10e-04 | |||
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.93 E-value: 9.10e-04
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EnvC | COG4942 | Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
420-510 | 1.32e-03 | |||
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]; Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 1.32e-03
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Blast search parameters | ||||
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