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Conserved domains on  [gi|1955007392|ref|NP_001376612|]
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golgin subfamily A member 3 isoform 1 [Homo sapiens]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000095)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
668-1339 3.01e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 117.46  E-value: 3.01e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  668 EDLQRRLEEFEGERERLQRMADSAAS----LEQQLEQVKLTLLQRDQQLEALQQEHL-------DLMKQLTLTQEALQSR 736
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAelqeLEEKLEELRLEVSELEEEIEELQKELYalaneisRLEQQKQILRERLANL 314
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  737 EQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREE 816
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQ 394
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  817 LAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDqlISELKATRKRLDSELKELRQELMQVHGEKRT 896
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAE--LEELEEELEELQEELERLEEALEELREELEE 472
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  897 AEAELSRLHREVAQVRQHMADLEGHLQSAQ----------KERDEMETHL----QSLQFDKEQMVAVTEA-NEALKKQIE 961
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallKNQSGLSGILgvlsELISVDEGYEAAIEAAlGGRLQAVVV 552
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  962 ELQQEARKAITEQKQKM----------RRLGSDLTSAQKEMKTKHkayENAVGILSRRLQEALAAKEAADAELGQLR--- 1028
Cdd:TIGR02168  553 ENLNAAKKAIAFLKQNElgrvtflpldSIKGTEIQGNDREILKNI---EGFLGVAKDLVKFDPKLRKALSYLLGGVLvvd 629
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1029 --AQGGSSDSSLALHERI----------------QALEAELQAVSHSKTLLE-----KELQEVIALTSQELEESREKVLE 1085
Cdd:TIGR02168  630 dlDNALELAKKLRPGYRIvtldgdlvrpggvitgGSAKTNSSILERRREIEEleekiEELEEKIAELEKALAELRKELEE 709
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1086 LEDEL-----------QESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNL 1154
Cdd:TIGR02168  710 LEEELeqlrkeleelsRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1155 QVQAVLQRKEEEDRQmkhlVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQ 1234
Cdd:TIGR02168  790 QIEQLKEELKALREA----LDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1235 AEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLD-LTEQ- 1312
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDnLQERl 945
                          730       740
                   ....*....|....*....|....*....
gi 1955007392 1313 --QGRKELEGLQQLLQNVKSELEMAQEDL 1339
Cdd:TIGR02168  946 seEYSLTLEEAEALENKIEDDEEEARRRL 974
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
345-982 4.14e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.26  E-value: 4.14e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  345 VNGQEIPADTLGQFPSIKDVLQAAAAEHQDQGQEVNGEVRSRRDSICSSVS----LESSAAETQEEMLQVLKEKMRLEGQ 420
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAeleeLESRLEELEEQLETLRSKVAQLELQ 394
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  421 LEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQrqDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLAS 500
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL--KELQAELEELEEELEELQEELERLEEALEELREELEE 472
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  501 SNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALqsqlqqvqlerttltSKLKASQAEISSLQSVRQWYQQ 580
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ---------------SGLSGILGVLSELISVDEGYEA 537
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  581 QLALAqearvrLQGEMAHIQVGQMTQAGL-LEHLK---------LENVSLSQQLTETQHRSMKEKGR-----------IA 639
Cdd:TIGR02168  538 AIEAA------LGGRLQAVVVENLNAAKKaIAFLKqnelgrvtfLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkFD 611
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  640 AQLQGIEADMLDQEAAFMQIQEAKTM-VEEDLQRRLEEFEGER-------------------ERLQRMADsaasLEQQLE 699
Cdd:TIGR02168  612 PKLRKALSYLLGGVLVVDDLDNALELaKKLRPGYRIVTLDGDLvrpggvitggsaktnssilERRREIEE----LEEKIE 687
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  700 QVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILE 779
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  780 AALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVE--AYRR 857
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEdlEEQI 847
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  858 DATSKDQL-----ISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEM 932
Cdd:TIGR02168  848 EELSEDIEslaaeIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1955007392  933 ETHLQSLQFD--------KEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLG 982
Cdd:TIGR02168  928 ELRLEGLEVRidnlqerlSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELG 985
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
668-1339 3.01e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 117.46  E-value: 3.01e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  668 EDLQRRLEEFEGERERLQRMADSAAS----LEQQLEQVKLTLLQRDQQLEALQQEHL-------DLMKQLTLTQEALQSR 736
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAelqeLEEKLEELRLEVSELEEEIEELQKELYalaneisRLEQQKQILRERLANL 314
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  737 EQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREE 816
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQ 394
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  817 LAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDqlISELKATRKRLDSELKELRQELMQVHGEKRT 896
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAE--LEELEEELEELQEELERLEEALEELREELEE 472
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  897 AEAELSRLHREVAQVRQHMADLEGHLQSAQ----------KERDEMETHL----QSLQFDKEQMVAVTEA-NEALKKQIE 961
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallKNQSGLSGILgvlsELISVDEGYEAAIEAAlGGRLQAVVV 552
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  962 ELQQEARKAITEQKQKM----------RRLGSDLTSAQKEMKTKHkayENAVGILSRRLQEALAAKEAADAELGQLR--- 1028
Cdd:TIGR02168  553 ENLNAAKKAIAFLKQNElgrvtflpldSIKGTEIQGNDREILKNI---EGFLGVAKDLVKFDPKLRKALSYLLGGVLvvd 629
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1029 --AQGGSSDSSLALHERI----------------QALEAELQAVSHSKTLLE-----KELQEVIALTSQELEESREKVLE 1085
Cdd:TIGR02168  630 dlDNALELAKKLRPGYRIvtldgdlvrpggvitgGSAKTNSSILERRREIEEleekiEELEEKIAELEKALAELRKELEE 709
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1086 LEDEL-----------QESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNL 1154
Cdd:TIGR02168  710 LEEELeqlrkeleelsRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1155 QVQAVLQRKEEEDRQmkhlVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQ 1234
Cdd:TIGR02168  790 QIEQLKEELKALREA----LDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1235 AEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLD-LTEQ- 1312
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDnLQERl 945
                          730       740
                   ....*....|....*....|....*....
gi 1955007392 1313 --QGRKELEGLQQLLQNVKSELEMAQEDL 1339
Cdd:TIGR02168  946 seEYSLTLEEAEALENKIEDDEEEARRRL 974
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
646-1197 3.00e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 104.25  E-value: 3.00e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  646 EADMLDQEAAFMQIQEAKTMVEEdLQRRLEEFEGERERLQRmadSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQ 725
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEE-LEAELEELEAELEELEA---ELAELEAELEELRLELEELELELEEAQAEEYELLAE 296
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  726 LTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEE 805
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  806 TSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQ 885
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  886 ELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQF---------------------DKE 944
Cdd:COG1196    457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAalllaglrglagavavligveAAY 536
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  945 QMVAVTEANEALKKQIEELQQEARKAITEQKQKmrrlgsDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAEL 1024
Cdd:COG1196    537 EAALEAALAAALQNIVVEDDEVAAAAIEYLKAA------KAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1025 GQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRgfrkkIKRLE 1104
Cdd:COG1196    611 ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE-----LEELA 685
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1105 ESNKKLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKE 1184
Cdd:COG1196    686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL 765
                          570
                   ....*....|...
gi 1955007392 1185 KEKVNSLKEQVAA 1197
Cdd:COG1196    766 ERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
345-982 4.14e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.26  E-value: 4.14e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  345 VNGQEIPADTLGQFPSIKDVLQAAAAEHQDQGQEVNGEVRSRRDSICSSVS----LESSAAETQEEMLQVLKEKMRLEGQ 420
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAeleeLESRLEELEEQLETLRSKVAQLELQ 394
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  421 LEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQrqDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLAS 500
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL--KELQAELEELEEELEELQEELERLEEALEELREELEE 472
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  501 SNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALqsqlqqvqlerttltSKLKASQAEISSLQSVRQWYQQ 580
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ---------------SGLSGILGVLSELISVDEGYEA 537
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  581 QLALAqearvrLQGEMAHIQVGQMTQAGL-LEHLK---------LENVSLSQQLTETQHRSMKEKGR-----------IA 639
Cdd:TIGR02168  538 AIEAA------LGGRLQAVVVENLNAAKKaIAFLKqnelgrvtfLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkFD 611
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  640 AQLQGIEADMLDQEAAFMQIQEAKTM-VEEDLQRRLEEFEGER-------------------ERLQRMADsaasLEQQLE 699
Cdd:TIGR02168  612 PKLRKALSYLLGGVLVVDDLDNALELaKKLRPGYRIVTLDGDLvrpggvitggsaktnssilERRREIEE----LEEKIE 687
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  700 QVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILE 779
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  780 AALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVE--AYRR 857
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEdlEEQI 847
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  858 DATSKDQL-----ISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEM 932
Cdd:TIGR02168  848 EELSEDIEslaaeIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1955007392  933 ETHLQSLQFD--------KEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLG 982
Cdd:TIGR02168  928 ELRLEGLEVRidnlqerlSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELG 985
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
842-1359 2.84e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 71.63  E-value: 2.84e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  842 KEQFLQQKVMVEayRRDATSKDQLISELKATRKrLDSELKELRQELMQVHGEKRTAEA---ELSRLHREVAQVRQHMADL 918
Cdd:PRK03918   181 LEKFIKRTENIE--ELIKEKEKELEEVLREINE-ISSELPELREELEKLEKEVKELEElkeEIEELEKELESLEGSKRKL 257
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  919 EGHLQSAQKERDEMETHLQSLqfdkEQMVAVTEANEALKKQIEELQQEARKaITEQKQKMRRLGSDLTSAQKEMKTKHKA 998
Cdd:PRK03918   258 EEKIRELEERIEELKKEIEEL----EEKVKELKELKEKAEEYIKLSEFYEE-YLDELREIEKRLSRLEEEINGIEERIKE 332
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  999 YENavgiLSRRLQEALAAKEAADAELGQLRaqggssdSSLALHERIQALEAELQavSHSKTLLEKELQEVIAltsqELEE 1078
Cdd:PRK03918   333 LEE----KEERLEELKKKLKELEKRLEELE-------ERHELYEEAKAKKEELE--RLKKRLTGLTPEKLEK----ELEE 395
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1079 SREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGqsnAALREHNSilETALAKREADLVQlnlqVQA 1158
Cdd:PRK03918   396 LEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCG---RELTEEHR--KELLEEYTAELKR----IEK 466
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1159 VLQRKEEEDRQMKHLVQALQASLEKEKE--KVNSLKEQVAAAKVE-AGHNRRHFKAASLELSEVKKELQAKEHLVQKLQA 1235
Cdd:PRK03918   467 ELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKlKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKK 546
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1236 EADDLQIREGKhSQEIAQFQAELAEARAQLqllqkqldeqlskqpvgNQEMENLKWE-VDQKEREIQSLKQQLD--LTEQ 1312
Cdd:PRK03918   547 ELEKLEELKKK-LAELEKKLDELEEELAEL-----------------LKELEELGFEsVEELEERLKELEPFYNeyLELK 608
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 1955007392 1313 QGRKELEGLQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELKNN 1359
Cdd:PRK03918   609 DAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKK 655
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
553-1244 6.73e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.45  E-value: 6.73e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  553 ERTTLTSKLKASQAEISSLQSVRQWYQQQlalaqeARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSQQLTETQHRSM 632
Cdd:pfam15921  279 EITGLTEKASSARSQANSIQSQLEIIQEQ------ARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLV 352
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  633 KEKGRIAAQLQgiEADMLDQEAAFMQIQEAKTMVeeDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQL 712
Cdd:pfam15921  353 LANSELTEART--ERDQFSQESGNLDDQLQKLLA--DLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEV 428
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  713 EALQQehldLMKqlTLTQEALQSREQSLDALQTHYDELQaRLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEEL 792
Cdd:pfam15921  429 QRLEA----LLK--AMKSECQGQMERQMAAIQGKNESLE-KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDL 501
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  793 DRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKK---QMQKIKEQFLQQKVMVEAYRRDATSKDQLISE- 868
Cdd:pfam15921  502 TASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNvqtECEALKLQMAEKDKVIEILRQQIENMTQLVGQh 581
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  869 ------LKATRKRLDSELKELRQELMQVHGEK-------RTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMeth 935
Cdd:pfam15921  582 grtagaMQVEKAQLEKEINDRRLELQEFKILKdkkdakiRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQL--- 658
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  936 LQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALA 1015
Cdd:pfam15921  659 LNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITA 738
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1016 AKEAADAELGQLR----AQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKELQeviALTSQElEESREKVLELEDELQ 1091
Cdd:pfam15921  739 KRGQIDALQSKIQfleeAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELE---VLRSQE-RRLKEKVANMEVALD 814
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1092 ESR----GFRKKIKRLEESNKKLALELEHEKGKLTGLG-QSNAALREHnsILETALAKREADLVQLNLQVQAVLQR---- 1162
Cdd:pfam15921  815 KASlqfaECQDIIQRQEQESVRLKLQHTLDVKELQGPGyTSNSSMKPR--LLQPASFTRTHSNVPSSQSTASFLSHhsrk 892
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1163 ----KEEEDRQMKHLVQALQASLEKEkEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEAD 1238
Cdd:pfam15921  893 tnalKEDPTRDLKQLLQELRSVINEE-PTVQLSKAEDKGRAPSLGALDDRVRDCIIESSLRSDICHSSSNSLQTEGSKSS 971

                   ....*.
gi 1955007392 1239 DLQIRE 1244
Cdd:pfam15921  972 ETCSRE 977
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
535-765 3.42e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.38  E-value: 3.42e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  535 DLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQvgqmtqagllEHLK 614
Cdd:COG4942     31 QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR----------AELE 100
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  615 LENVSLSQQLTETQhrSMKEKGRIAAQLQGieADMLDQEAAFMQIQEaktmVEEDLQRRLEEFEGERERLQRMADSAASL 694
Cdd:COG4942    101 AQKEELAELLRALY--RLGRQPPLALLLSP--EDFLDAVRRLQYLKY----LAPARREQAEELRADLAELAALRAELEAE 172
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1955007392  695 EQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLtltQEALQSREQSLDALQTHYDELQARLGELQGEAASRE 765
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLLARL---EKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
365-963 1.32e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 53.30  E-value: 1.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  365 LQAAAAEHQDQGQEVNGEVRSRRDSICSSVSlESSAAETQEemLQVLKEKM-RLEGQLEALSLEASQALKEKAE------ 437
Cdd:pfam12128  270 DETLIASRQEERQETSAELNQLLRTLDDQWK-EKRDELNGE--LSAADAAVaKDRSELEALEDQHGAFLDADIEtaaadq 346
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  438 -----LQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVDtlKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQY 512
Cdd:pfam12128  347 eqlpsWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK--EQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESEL 424
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  513 ------QRLMAKVEDMQ--------RSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISSLQSVRQWY 578
Cdd:pfam12128  425 reqleaGKLEFNEEEYRlksrlgelKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQA 504
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  579 QQQLALAQEARVRLQGEMAHIQVGQMTQAG-LLEHLKLENVSLSQQL-----TETQHRSMKEKGRIAAQLQG---IEADM 649
Cdd:pfam12128  505 SEALRQASRRLEERQSALDELELQLFPQAGtLLHFLRKEAPDWEQSIgkvisPELLHRTDLDPEVWDGSVGGelnLYGVK 584
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  650 LDQEAafMQIQEAKTMvEEDLQRRLEEFEgerERLQRMADSAASLEQQLEQVKLTLLQRDQQLE----ALQQEHLDLM-- 723
Cdd:pfam12128  585 LDLKR--IDVPEWAAS-EEELRERLDKAE---EALQSAREKQAAAEEQLVQANGELEKASREETfartALKNARLDLRrl 658
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  724 ------------KQLTLTQEALQSREQSLDALQTHYD-ELQARLGELQGEaaSREDTICLLQNEKII---LEAALQAAKS 787
Cdd:pfam12128  659 fdekqsekdkknKALAERKDSANERLNSLEAQLKQLDkKHQAWLEEQKEQ--KREARTEKQAYWQVVegaLDAQLALLKA 736
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  788 GKEELDRGARRLEEGTEETSETLEKLR----EELAIKSGQVEHLQQETAALKKQMQKIKE--QFLQQKVMVEAYRRDATS 861
Cdd:pfam12128  737 AIAARRSGAKAELKALETWYKRDLASLgvdpDVIAKLKREIRTLERKIERIAVRRQEVLRyfDWYQETWLQRRPRLATQL 816
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  862 KD--QLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSL 939
Cdd:pfam12128  817 SNieRAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGERLAQLE 896
                          650       660
                   ....*....|....*....|....
gi 1955007392  940 QFDKEQMVAVteanEALKKQIEEL 963
Cdd:pfam12128  897 DLKLKRDYLS----ESVKKYVEHF 916
PRK11281 PRK11281
mechanosensitive channel MscK;
367-638 5.16e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.90  E-value: 5.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  367 AAAAEHQDQGQEvnGEVRSRRDSICSSVSLESSAAETQ---EEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLA 443
Cdd:PRK11281    27 ARAASNGDLPTE--ADVQAQLDALNKQKLLEAEDKLVQqdlEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELE 104
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  444 ALSTKLQAQVecshssQQRQDSLSseVDTLKQSCWDLERAMTDLQNMLEAKNASLASsnndLQVAEEQYQRLMAkvEDMQ 523
Cdd:PRK11281   105 ALKDDNDEET------RETLSTLS--LRQLESRLAQTLDQLQNAQNDLAEYNSQLVS----LQTQPERAQAALY--ANSQ 170
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  524 RSM----------LSKDNTVHDLRQQMTALQSQLQQVQLERTTLTsklkasqAEISSLQSVrqwYQQQLALAQEARVRLQ 593
Cdd:PRK11281   171 RLQqirnllkggkVGGKALRPSQRVLLQAEQALLNAQNDLQRKSL-------EGNTQLQDL---LQKQRDYLTARIQRLE 240
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1955007392  594 GEMAHIQvgqmtqagllEHLKLENVSLSQQlTETQHRSMKEKGRI 638
Cdd:PRK11281   241 HQLQLLQ----------EAINSKRLTLSEK-TVQEAQSQDEAARI 274
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
668-1339 3.01e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 117.46  E-value: 3.01e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  668 EDLQRRLEEFEGERERLQRMADSAAS----LEQQLEQVKLTLLQRDQQLEALQQEHL-------DLMKQLTLTQEALQSR 736
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAelqeLEEKLEELRLEVSELEEEIEELQKELYalaneisRLEQQKQILRERLANL 314
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  737 EQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREE 816
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQ 394
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  817 LAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDqlISELKATRKRLDSELKELRQELMQVHGEKRT 896
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAE--LEELEEELEELQEELERLEEALEELREELEE 472
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  897 AEAELSRLHREVAQVRQHMADLEGHLQSAQ----------KERDEMETHL----QSLQFDKEQMVAVTEA-NEALKKQIE 961
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallKNQSGLSGILgvlsELISVDEGYEAAIEAAlGGRLQAVVV 552
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  962 ELQQEARKAITEQKQKM----------RRLGSDLTSAQKEMKTKHkayENAVGILSRRLQEALAAKEAADAELGQLR--- 1028
Cdd:TIGR02168  553 ENLNAAKKAIAFLKQNElgrvtflpldSIKGTEIQGNDREILKNI---EGFLGVAKDLVKFDPKLRKALSYLLGGVLvvd 629
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1029 --AQGGSSDSSLALHERI----------------QALEAELQAVSHSKTLLE-----KELQEVIALTSQELEESREKVLE 1085
Cdd:TIGR02168  630 dlDNALELAKKLRPGYRIvtldgdlvrpggvitgGSAKTNSSILERRREIEEleekiEELEEKIAELEKALAELRKELEE 709
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1086 LEDEL-----------QESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNL 1154
Cdd:TIGR02168  710 LEEELeqlrkeleelsRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1155 QVQAVLQRKEEEDRQmkhlVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQ 1234
Cdd:TIGR02168  790 QIEQLKEELKALREA----LDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1235 AEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLD-LTEQ- 1312
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDnLQERl 945
                          730       740
                   ....*....|....*....|....*....
gi 1955007392 1313 --QGRKELEGLQQLLQNVKSELEMAQEDL 1339
Cdd:TIGR02168  946 seEYSLTLEEAEALENKIEDDEEEARRRL 974
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
646-1197 3.00e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 104.25  E-value: 3.00e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  646 EADMLDQEAAFMQIQEAKTMVEEdLQRRLEEFEGERERLQRmadSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQ 725
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEE-LEAELEELEAELEELEA---ELAELEAELEELRLELEELELELEEAQAEEYELLAE 296
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  726 LTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEE 805
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  806 TSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQ 885
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  886 ELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQF---------------------DKE 944
Cdd:COG1196    457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAalllaglrglagavavligveAAY 536
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  945 QMVAVTEANEALKKQIEELQQEARKAITEQKQKmrrlgsDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAEL 1024
Cdd:COG1196    537 EAALEAALAAALQNIVVEDDEVAAAAIEYLKAA------KAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1025 GQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRgfrkkIKRLE 1104
Cdd:COG1196    611 ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE-----LEELA 685
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1105 ESNKKLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKE 1184
Cdd:COG1196    686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL 765
                          570
                   ....*....|...
gi 1955007392 1185 KEKVNSLKEQVAA 1197
Cdd:COG1196    766 ERELERLEREIEA 778
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
633-1340 1.68e-21

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 102.07  E-value: 1.68e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  633 KEKGRIAAQLQGIEADMLDQEAAFMQI-QEAKTMVEED---LQRRLEEFEGERERLQRmadSAASLEQQLEQVKLTLLQR 708
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELnKKIKDLGEEEqlrVKEKIGELEAEIASLER---SIAEKERELEDAEERLAKL 327
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  709 DQQLEALQQEHLDLmkqltltQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSG 788
Cdd:TIGR02169  328 EAEIDKLLAEIEEL-------EREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKRE 400
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  789 KEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDatskdqlISE 868
Cdd:TIGR02169  401 INELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE-------LYD 473
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  869 LKATRKRLDSELKELRQELMQVHGEKRTAEaelSRLHREVAQVRQHMADLEG-HLQSAQ--KERDEMETHLQSLQFDKEQ 945
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQRELAEAEAQARASE---ERVRGGRAVEEVLKASIQGvHGTVAQlgSVGERYATAIEVAAGNRLN 550
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  946 MVaVTEANEALKKQIEELQQE-ARKAITEQKQKMRRLGSDLTSAQKE--------MKTKHKAYENAV------GILSRRL 1010
Cdd:TIGR02169  551 NV-VVEDDAVAKEAIELLKRRkAGRATFLPLNKMRDERRDLSILSEDgvigfavdLVEFDPKYEPAFkyvfgdTLVVEDI 629
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1011 QEALAAKEAAD--AELGQLRAQGGS----SDSSLALHERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKVL 1084
Cdd:TIGR02169  630 EAARRLMGKYRmvTLEGELFEKSGAmtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1085 ELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVlqrke 1164
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL----- 784
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1165 eEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAakVEAGHNRRHFKAASLElsEVKKELQAKEHLVQ----KLQAEADDL 1240
Cdd:TIGR02169  785 -EARLSHSRIPEIQAELSKLEEEVSRIEARLRE--IEQKLNRLTLEKEYLE--KEIQELQEQRIDLKeqikSIEKEIENL 859
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1241 QIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLDLTEQQgrkeleg 1320
Cdd:TIGR02169  860 NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE------- 932
                          730       740
                   ....*....|....*....|
gi 1955007392 1321 LQQLLQNVKSELEMAQEDLS 1340
Cdd:TIGR02169  933 LSEIEDPKGEDEEIPEEELS 952
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
671-1343 2.87e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 101.29  E-value: 2.87e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  671 QRRLEEfegERERLQRMADSAASLEQQLE----QVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTH 746
Cdd:TIGR02168  178 ERKLER---TRENLDRLEDILNELERQLKslerQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEE 254
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  747 YDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEH 826
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDE 334
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  827 LQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHR 906
Cdd:TIGR02168  335 LAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLED 414
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  907 EVAQVRQHMADLEGHLQSAQKERDEMEthLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLT 986
Cdd:TIGR02168  415 RRERLQQEIEELLKKLEEAELKELQAE--LEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  987 SAQKEMKTKHKAYENAVGILSRRLQEALAAkeaadaelgQLRAQGGSSDS------SLALHERIQAL-----EAELQAVS 1055
Cdd:TIGR02168  493 SLERLQENLEGFSEGVKALLKNQSGLSGIL---------GVLSELISVDEgyeaaiEAALGGRLQAVvvenlNAAKKAIA 563
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1056 HsktLLEKELQEV--IALTSQELEESREKVLELedeLQESRGFRKKIKRLEESNKKL-------------------ALEL 1114
Cdd:TIGR02168  564 F---LKQNELGRVtfLPLDSIKGTEIQGNDREI---LKNIEGFLGVAKDLVKFDPKLrkalsyllggvlvvddldnALEL 637
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1115 EHE----------KGKLTGLG--QSNAALREHNSILETA-----LAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQAL 1177
Cdd:TIGR02168  638 AKKlrpgyrivtlDGDLVRPGgvITGGSAKTNSSILERRreieeLEEKIEELEEKIAELEKALAELRKELEELEEELEQL 717
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1178 QASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAE 1257
Cdd:TIGR02168  718 RKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE 797
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1258 LAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLDLTEQQG---RKELEGLQQLLQNVKSELEM 1334
Cdd:TIGR02168  798 LKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIeslAAEIEELEELIEELESELEA 877

                   ....*....
gi 1955007392 1335 AQEDLSMTQ 1343
Cdd:TIGR02168  878 LLNERASLE 886
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
417-982 3.85e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 100.78  E-value: 3.85e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  417 LEGQLEALSLEASQALK------EKAELQAQLAALSTKLQaqvecshssQQRQDSLSSEVDTLKQSCWDLERAMTDLQNM 490
Cdd:COG1196    198 LERQLEPLERQAEKAERyrelkeELKELEAELLLLKLREL---------EAELEELEAELEELEAELEELEAELAELEAE 268
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  491 LEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISS 570
Cdd:COG1196    269 LEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEE 348
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  571 LQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHL---KLENVSLSQQLTETQHRSMKEKGRIAAQLQGIEA 647
Cdd:COG1196    349 AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAlraAAELAAQLEELEEAEEALLERLERLEEELEELEE 428
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  648 DMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLT 727
Cdd:COG1196    429 ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  728 LTQEALQSREQSLDALQTH-------------YDELQARLGELQGEAASREDTICLLQNEK-----------IILEAALQ 783
Cdd:COG1196    509 GVKAALLLAGLRGLAGAVAvligveaayeaalEAALAAALQNIVVEDDEVAAAAIEYLKAAkagratflpldKIRARAAL 588
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  784 AAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKD 863
Cdd:COG1196    589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  864 QLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEghlQSAQKERDEMETHLQSLQFDK 943
Cdd:COG1196    669 ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE---ALEEQLEAEREELLEELLEEE 745
                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1955007392  944 EQMVAVTEANEALKKQIEELQQEARKAiteqKQKMRRLG 982
Cdd:COG1196    746 ELLEEEALEELPEPPDLEELERELERL----EREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
671-1263 1.20e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.24  E-value: 1.20e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  671 QRRLEEfegERERLQRMADSAASLEQQLEQVKLtllQRDQQLEALQQehldlmkqltltQEALQSREQSLDALqtHYDEL 750
Cdd:COG1196    178 ERKLEA---TEENLERLEDILGELERQLEPLER---QAEKAERYREL------------KEELKELEAELLLL--KLREL 237
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  751 QARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQE 830
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  831 TAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQ 910
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  911 VRQHMADLEGHLQSAQKERDEMETHLQSLQfdkEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQK 990
Cdd:COG1196    398 LAAQLEELEEAEEALLERLERLEEELEELE---EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  991 EMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQG--GSSDSSLALHERIQ-------ALEAELQAVS-HSKTL 1060
Cdd:COG1196    475 LEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLlaGLRGLAGAVAVLIGveaayeaALEAALAAALqNIVVE 554
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1061 LEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALREHNSILET 1140
Cdd:COG1196    555 DDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1141 A---LAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQAL---QASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASL 1214
Cdd:COG1196    635 AlrrAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALleaEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 1955007392 1215 ELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELAEARA 1263
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE 763
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
401-1189 1.15e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.28  E-value: 1.15e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  401 AETQEEMLQV---LKEkmrLEGQLEALSLEASQALKEKaELQAQLAALSTKLQAQVecSHSSQQRQDSLSSEVDTLKQSC 477
Cdd:TIGR02168  182 ERTRENLDRLediLNE---LERQLKSLERQAEKAERYK-ELKAELRELELALLVLR--LEELREELEELQEELKEAEEEL 255
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  478 WDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTL 557
Cdd:TIGR02168  256 EELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL 335
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  558 TSKLKASQAEISSLQSVRQWYQQQL----ALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLEN---VSLSQQLTETQHR 630
Cdd:TIGR02168  336 AEELAELEEKLEELKEELESLEAELeeleAELEELESRLEELEEQLETLRSKVAQLELQIASLNneiERLEARLERLEDR 415
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  631 SMKEKGRIAAQLQGI-EADMLDQEAAFMQIQEAKTMVE---EDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLL 706
Cdd:TIGR02168  416 RERLQQEIEELLKKLeEAELKELQAELEELEEELEELQeelERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  707 QRDQQLEALQQEHLDLMKQ-------LTLTQEALQSREQ-----------SLDALQTHYDELQARLGELQGEAASREDTI 768
Cdd:TIGR02168  496 RLQENLEGFSEGVKALLKNqsglsgiLGVLSELISVDEGyeaaieaalggRLQAVVVENLNAAKKAIAFLKQNELGRVTF 575
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  769 CLLqneKIILEAALQAAKSGKEELDRGARRLEEGTEETSET------------------------LEKLREELAI----- 819
Cdd:TIGR02168  576 LPL---DSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvvddldnalelAKKLRPGYRIvtldg 652
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  820 ---------------KSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELR 884
Cdd:TIGR02168  653 dlvrpggvitggsakTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALR 732
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  885 QELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQfdkEQMVAVTEANEALKKQIEELQ 964
Cdd:TIGR02168  733 KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELE---AQIEQLKEELKALREALDELR 809
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  965 QEarkaITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRaqggssdsslALHERI 1044
Cdd:TIGR02168  810 AE----LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE----------ELESEL 875
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1045 QALEAELQAVSHSKTLLEKELQEVialtSQELEESREKVLELEDELQESrgfRKKIKRLEESNKKLALELEHEKGKLTGL 1124
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEEL----SEELRELESKRSELRRELEEL---REKLAQLELRLEGLEVRIDNLQERLSEE 948
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1125 GQSNA-ALREHNSILETALAKREADLVQLNLQV--------------QAVLQRKEEEDRQMKHLVQALqASLEKEKEKVN 1189
Cdd:TIGR02168  949 YSLTLeEAEALENKIEDDEEEARRRLKRLENKIkelgpvnlaaieeyEELKERYDFLTAQKEDLTEAK-ETLEEAIEEID 1027
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
813-1448 3.34e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.15  E-value: 3.34e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  813 LREELAiksGQVEHLQQEtAALKKQMQKIKEQFLQQKVMVEAYRRDatskdqlisELKATRKRLDSELKELRQELMQVHG 892
Cdd:COG1196    194 ILGELE---RQLEPLERQ-AEKAERYRELKEELKELEAELLLLKLR---------ELEAELEELEAELEELEAELEELEA 260
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  893 EKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMEthlQSLQFDKEQMVAVTEANEALKKQIEELQQEarkaIT 972
Cdd:COG1196    261 ELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE---QDIARLEERRRELEERLEELEEELAELEEE----LE 333
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  973 EQKQKMRRLGSDLTSAQKEMKTKHKAYENAvgiLSRRLQEALAAKEAADAELGQLRAQGGSSDSSLALHERIQALEAELQ 1052
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEA---EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1053 AvshSKTLLEKELQEVIALTSQELEESREKVLELEDELQEsrgfRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALR 1132
Cdd:COG1196    411 A---LLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1133 EHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVnslkEQVAAAKVEAGHNRRHFKAA 1212
Cdd:COG1196    484 EELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAA----LEAALAAALQNIVVEDDEVA 559
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1213 SLELSEVKKELQAK------EHLVQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEM 1286
Cdd:COG1196    560 AAAIEYLKAAKAGRatflplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA 639
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1287 ENLKWEVDQKEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELKNNMKTLLQQ 1366
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1367 NQQLKLDLRRGAAKTRKEPkgeasssnpatpikipdcpvpASLLEELLRPPPAVSKEPLKNLNscLQQLKQEMDSLQRQM 1446
Cdd:COG1196    720 ELEEEALEEQLEAEREELL---------------------EELLEEEELLEEEALEELPEPPD--LEELERELERLEREI 776

                   ..
gi 1955007392 1447 EE 1448
Cdd:COG1196    777 EA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
365-970 1.04e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.14  E-value: 1.04e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  365 LQAAAAEHQDQGQEVNGEVRSRRDSIcssVSLESSAAETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAA 444
Cdd:COG1196    251 LEAELEELEAELAELEAELEELRLEL---EELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  445 LSTKLQAQvecshssQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQR 524
Cdd:COG1196    328 LEEELEEL-------EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  525 SMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQM 604
Cdd:COG1196    401 QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  605 TQAGLLEHLKLENVSLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAfmqiqeaktmVEEDLQRRLEEFEGEReRL 684
Cdd:COG1196    481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG----------VEAAYEAALEAALAAA-LQ 549
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  685 QRMADSAASLEQQLEQVKLTLLQRDQQLEalqqehLDLMKQLTLTQEALQSREQSLDALQTHYD--ELQARLGELQGEAA 762
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRATFLP------LDKIRARAALAAALARGAIGAAVDLVASDlrEADARYYVLGDTLL 623
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  763 SREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIK 842
Cdd:COG1196    624 GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEE 703
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  843 EQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHL 922
Cdd:COG1196    704 EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPVN 783
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1955007392  923 QSAQKERDEMETHLQSLqfdKEQMVAVTEANEALKKQIEELQQEARKA 970
Cdd:COG1196    784 LLAIEEYEELEERYDFL---SEQREDLEEARETLEEAIEEIDRETRER 828
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
395-981 3.61e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 3.61e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  395 SLESSAAETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQ-------DSLS 467
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLeelkeelESLE 357
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  468 SEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQ-----QMTA 542
Cdd:TIGR02168  358 AELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKkleeaELKE 437
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  543 LQSQLQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLK-------- 614
Cdd:TIGR02168  438 LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKallknqsg 517
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  615 ---------------------LENV-----------SLSQQLTETQHRSMKEKGRIA---------AQLQGIEADMLDQE 653
Cdd:TIGR02168  518 lsgilgvlselisvdegyeaaIEAAlggrlqavvveNLNAAKKAIAFLKQNELGRVTflpldsikgTEIQGNDREILKNI 597
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  654 AAFMQIQEAKTMVEEDLQRRLEEFEG------------ERERLQRMADSAASLEQQL-----------EQVKLTLLQRDQ 710
Cdd:TIGR02168  598 EGFLGVAKDLVKFDPKLRKALSYLLGgvlvvddldnalELAKKLRPGYRIVTLDGDLvrpggvitggsAKTNSSILERRR 677
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  711 QLEalqqehlDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKE 790
Cdd:TIGR02168  678 EIE-------ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  791 ELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFlqqkvmvEAYRRDATSKDQLISELK 870
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAL-------DELRAELTLLNEEAANLR 823
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  871 ATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVT 950
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEEL 903
                          650       660       670
                   ....*....|....*....|....*....|.
gi 1955007392  951 EANEALKKQIEELQQEARKAITEQKQKMRRL 981
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLELRLEGL 934
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
345-982 4.14e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.26  E-value: 4.14e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  345 VNGQEIPADTLGQFPSIKDVLQAAAAEHQDQGQEVNGEVRSRRDSICSSVS----LESSAAETQEEMLQVLKEKMRLEGQ 420
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAeleeLESRLEELEEQLETLRSKVAQLELQ 394
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  421 LEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQrqDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLAS 500
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL--KELQAELEELEEELEELQEELERLEEALEELREELEE 472
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  501 SNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALqsqlqqvqlerttltSKLKASQAEISSLQSVRQWYQQ 580
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ---------------SGLSGILGVLSELISVDEGYEA 537
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  581 QLALAqearvrLQGEMAHIQVGQMTQAGL-LEHLK---------LENVSLSQQLTETQHRSMKEKGR-----------IA 639
Cdd:TIGR02168  538 AIEAA------LGGRLQAVVVENLNAAKKaIAFLKqnelgrvtfLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkFD 611
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  640 AQLQGIEADMLDQEAAFMQIQEAKTM-VEEDLQRRLEEFEGER-------------------ERLQRMADsaasLEQQLE 699
Cdd:TIGR02168  612 PKLRKALSYLLGGVLVVDDLDNALELaKKLRPGYRIVTLDGDLvrpggvitggsaktnssilERRREIEE----LEEKIE 687
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  700 QVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILE 779
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  780 AALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVE--AYRR 857
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEdlEEQI 847
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  858 DATSKDQL-----ISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEM 932
Cdd:TIGR02168  848 EELSEDIEslaaeIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1955007392  933 ETHLQSLQFD--------KEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLG 982
Cdd:TIGR02168  928 ELRLEGLEVRidnlqerlSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELG 985
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
402-1243 9.93e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.65  E-value: 9.93e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  402 ETQEEMLQVLKEKMRLEGQLEALSLEAsqALKEKAELQAQLAALS---TKLQAQVecshssQQRQDSLSSEVDTLKQSCW 478
Cdd:TIGR02169  208 EKAERYQALLKEKREYEGYELLKEKEA--LERQKEAIERQLASLEeelEKLTEEI------SELEKRLEEIEQLLEELNK 279
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  479 DLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMakvEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLT 558
Cdd:TIGR02169  280 KIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKEREL---EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLT 356
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  559 SKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEmahiqvgqmtqaglLEHLKLENVSLSQqlteTQHRSMKEKGRI 638
Cdd:TIGR02169  357 EEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK--------------LEKLKREINELKR----ELDRLQEELQRL 418
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  639 AAQLQGIEADMLDQEAAFMQIQEAKtmveEDLQRRLEEFEGERERLQRMADSAaslEQQLEQVKLTLLQRDQQLEALQQE 718
Cdd:TIGR02169  419 SEELADLNAAIAGIEAKINELEEEK----EDKALEIKKQEWKLEQLAADLSKY---EQELYDLKEEYDRVEKELSKLQRE 491
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  719 hldlMKQLTLTQEALQSREQSLDALQTHYDE-------LQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEE 791
Cdd:TIGR02169  492 ----LAEAEAQARASEERVRGGRAVEEVLKAsiqgvhgTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELL 567
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  792 LDRGARRLEEGTEETSETLEKLREELAiKSGQVEHLqQETAALKKQMQKIKEQFLQQKVMV---EAYRR----------- 857
Cdd:TIGR02169  568 KRRKAGRATFLPLNKMRDERRDLSILS-EDGVIGFA-VDLVEFDPKYEPAFKYVFGDTLVVediEAARRlmgkyrmvtle 645
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  858 -DATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHL 936
Cdd:TIGR02169  646 gELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI 725
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  937 QSLQFDKEQmvaVTEANEALKKQIEELQQEarkaITEQKQKMRRLGSDLtsaqKEMKTKHKAYENAVGILSRRLqealaA 1016
Cdd:TIGR02169  726 EQLEQEEEK---LKERLEELEEDLSSLEQE----IENVKSELKELEARI----EELEEDLHKLEEALNDLEARL-----S 789
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1017 KEAADAELGQLRAQggsSDSSLALHERIQALEAELQAVSHSKTLLEKELQEVIaltsQELEESREKVLELEDELQESRGF 1096
Cdd:TIGR02169  790 HSRIPEIQAELSKL---EEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQ----EQRIDLKEQIKSIEKEIENLNGK 862
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1097 RKKIKRLEESNKKLALELEHEKGKLTG----LGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKH 1172
Cdd:TIGR02169  863 KEELEEELEELEAALRDLESRLGDLKKerdeLEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE 942
                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1955007392 1173 LVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRrhfkaASLELSEVKKELQAKEHLVQKLQAEADDLQIR 1243
Cdd:TIGR02169  943 DEEIPEEELSLEDVQAELQRVEEEIRALEPVNML-----AIQEYEEVLKRLDELKEKRAKLEEERKAILER 1008
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
649-1262 1.47e-12

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 72.64  E-value: 1.47e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  649 MLDQEAAFMQIQEAKTMVEE--DLQRRLEEFEGERERLQRMADSAASLEQQLEQV-KLTLLQRDQQLEALQQEHLDLMKQ 725
Cdd:COG4913    217 MLEEPDTFEAADALVEHFDDleRAHEALEDAREQIELLEPIRELAERYAAARERLaELEYLRAALRLWFAQRRLELLEAE 296
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  726 LTLTQEALQSREQSLDALQTHYDELQARLGELQGEaasredticllqnekiILEAALQAAKSGKEELDRgarrleegtee 805
Cdd:COG4913    297 LEELRAELARLEAELERLEARLDALREELDELEAQ----------------IRGNGGDRLEQLEREIER----------- 349
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  806 tsetlekLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKvmveayrrdatskdqliSELKATRKRLDSELKELRQ 885
Cdd:COG4913    350 -------LERELEERERRRARLEALLAALGLPLPASAEEFAALR-----------------AEAAALLEALEEELEALEE 405
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  886 ELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAqkeRDEMETHLQ----SLQFDKEqMVAVTEANEALKKQIE 961
Cdd:COG4913    406 ALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLAL---RDALAEALGldeaELPFVGE-LIEVRPEEERWRGAIE 481
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  962 --------------ELQQEARKAITEQKQKMR----RLGSDLTSAQK----------EMKTK-HKAYENAVGILSRRL-- 1010
Cdd:COG4913    482 rvlggfaltllvppEHYAAALRWVNRLHLRGRlvyeRVRTGLPDPERprldpdslagKLDFKpHPFRAWLEAELGRRFdy 561
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1011 --------------------QEALAAKEAADAELGQLRAQ---GGSSDSSLA-LHERIQALEAELQAVSHSKTLLEKELQ 1066
Cdd:COG4913    562 vcvdspeelrrhpraitragQVKGNGTRHEKDDRRRIRSRyvlGFDNRAKLAaLEAELAELEEELAEAEERLEALEAELD 641
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1067 EVIAL-----TSQELEESREKVLELEDELQEsrgFRKKIKRLEESN---KKLALELEHEKGKLTGLGQSNAALREHNSIL 1138
Cdd:COG4913    642 ALQERrealqRLAEYSWDEIDVASAEREIAE---LEAELERLDASSddlAALEEQLEELEAELEELEEELDELKGEIGRL 718
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1139 ETALAKREADLVQLNLQVQAVLQRKEEE--------------DRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAgh 1204
Cdd:COG4913    719 EKELEQAEEELDELQDRLEAAEDLARLElralleerfaaalgDAVERELRENLEERIDALRARLNRAEEELERAMRAF-- 796
                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1955007392 1205 nRRHFKAASLELSEvkkELQAKEHLVQKLQA-EADDL-----QIREGKHS---QEIAQFQAELAEAR 1262
Cdd:COG4913    797 -NREWPAETADLDA---DLESLPEYLALLDRlEEDGLpeyeeRFKELLNEnsiEFVADLLSKLRRAI 859
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
842-1359 2.84e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 71.63  E-value: 2.84e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  842 KEQFLQQKVMVEayRRDATSKDQLISELKATRKrLDSELKELRQELMQVHGEKRTAEA---ELSRLHREVAQVRQHMADL 918
Cdd:PRK03918   181 LEKFIKRTENIE--ELIKEKEKELEEVLREINE-ISSELPELREELEKLEKEVKELEElkeEIEELEKELESLEGSKRKL 257
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  919 EGHLQSAQKERDEMETHLQSLqfdkEQMVAVTEANEALKKQIEELQQEARKaITEQKQKMRRLGSDLTSAQKEMKTKHKA 998
Cdd:PRK03918   258 EEKIRELEERIEELKKEIEEL----EEKVKELKELKEKAEEYIKLSEFYEE-YLDELREIEKRLSRLEEEINGIEERIKE 332
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  999 YENavgiLSRRLQEALAAKEAADAELGQLRaqggssdSSLALHERIQALEAELQavSHSKTLLEKELQEVIAltsqELEE 1078
Cdd:PRK03918   333 LEE----KEERLEELKKKLKELEKRLEELE-------ERHELYEEAKAKKEELE--RLKKRLTGLTPEKLEK----ELEE 395
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1079 SREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGqsnAALREHNSilETALAKREADLVQlnlqVQA 1158
Cdd:PRK03918   396 LEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCG---RELTEEHR--KELLEEYTAELKR----IEK 466
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1159 VLQRKEEEDRQMKHLVQALQASLEKEKE--KVNSLKEQVAAAKVE-AGHNRRHFKAASLELSEVKKELQAKEHLVQKLQA 1235
Cdd:PRK03918   467 ELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKlKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKK 546
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1236 EADDLQIREGKhSQEIAQFQAELAEARAQLqllqkqldeqlskqpvgNQEMENLKWE-VDQKEREIQSLKQQLD--LTEQ 1312
Cdd:PRK03918   547 ELEKLEELKKK-LAELEKKLDELEEELAEL-----------------LKELEELGFEsVEELEERLKELEPFYNeyLELK 608
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 1955007392 1313 QGRKELEGLQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELKNN 1359
Cdd:PRK03918   609 DAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKK 655
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
667-1202 5.45e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 70.86  E-value: 5.45e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  667 EEDLQRRLEEFEGERERLQRMADSAASLEQQL-------EQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQS 739
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELreeleklEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEER 267
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  740 LDALQTHYDELQ---ARLGELQGEA-------ASREDTICLLQNEKIILEAALQAAKSGKEELDRgARRLEEGTEETSET 809
Cdd:PRK03918   268 IEELKKEIEELEekvKELKELKEKAeeyiklsEFYEEYLDELREIEKRLSRLEEEINGIEERIKE-LEEKEERLEELKKK 346
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  810 LEKLREELAIKSGQVEhLQQETAALKKQMQKIKEQFLQQKV-----MVEAYRRDATSKDQLISELKATRKRLDSELKELR 884
Cdd:PRK03918   347 LKELEKRLEELEERHE-LYEEAKAKKEELERLKKRLTGLTPeklekELEELEKAKEEIEEEISKITARIGELKKEIKELK 425
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  885 QELMQVHGEKRTA-----------EAEL-SRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQS---LQFDKEQMVAV 949
Cdd:PRK03918   426 KAIEELKKAKGKCpvcgrelteehRKELlEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKeseLIKLKELAEQL 505
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  950 TEANEALKK-QIEELQQEARKAiTEQKQKMRRLGSDLTSAQKEMKtKHKAYENAVGILSRRLQealAAKEAADAELGQLR 1028
Cdd:PRK03918   506 KELEEKLKKyNLEELEKKAEEY-EKLKEKLIKLKGEIKSLKKELE-KLEELKKKLAELEKKLD---ELEEELAELLKELE 580
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1029 AQGGSSDSSlaLHERIQALEA---ELQAVSHSKTLLEKELQEvIALTSQELEESREKVLELEDELQESRgfrkkiKRLEE 1105
Cdd:PRK03918   581 ELGFESVEE--LEERLKELEPfynEYLELKDAEKELEREEKE-LKKLEEELDKAFEELAETEKRLEELR------KELEE 651
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1106 SNKKLALElEHEKgkltglgqsnaaLREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQ--ASLEK 1183
Cdd:PRK03918   652 LEKKYSEE-EYEE------------LREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKelEKLEK 718
                          570
                   ....*....|....*....
gi 1955007392 1184 EKEKVNSLKEQVAAAKVEA 1202
Cdd:PRK03918   719 ALERVEELREKVKKYKALL 737
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
630-1333 6.76e-12

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 70.77  E-value: 6.76e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  630 RSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVE-EDLQRRLEEFEGErERLQRMADSAASLEQQLEQVKLTLLQR 708
Cdd:TIGR00618  160 AKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAElLTLRSQLLTLCTP-CMPDTYHERKQVLEKELKHLREALQQT 238
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  709 DQQLEALQQEHLdlmkqltlTQEALQSREQSLDALQTHYDELQ---ARLGELQGEAASREDTICLLQNEKIILEAALQAA 785
Cdd:TIGR00618  239 QQSHAYLTQKRE--------AQEEQLKKQQLLKQLRARIEELRaqeAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQ 310
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  786 KSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQK-IKEQFLQQKVMVEAYRRDATSKDQ 864
Cdd:TIGR00618  311 RIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATsIREISCQQHTLTQHIHTLQQQKTT 390
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  865 LISELKATRKRLDSELKE-------------LRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDE 931
Cdd:TIGR00618  391 LTQKLQSLCKELDILQREqatidtrtsafrdLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKE 470
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  932 METHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLG--SDLTSAQKEMKTKHKAYENAVGILSRR 1009
Cdd:TIGR00618  471 REQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDnpGPLTRRMQRGEQTYAQLETSEEDVYHQ 550
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1010 LQEALAAKEAADAELGQLRaqggssDSSLALHERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDE 1089
Cdd:TIGR00618  551 LTSERKQRASLKEQMQEIQ------QSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPE 624
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1090 LQESRgfrkKIKRLEESNKKLALELEHEKGKLTGLGQSNaalrehnsILETALAKREADLvQLNLQVQAVLQRKEEEDRQ 1169
Cdd:TIGR00618  625 QDLQD----VRLHLQQCSQELALKLTALHALQLTLTQER--------VREHALSIRVLPK-ELLASRQLALQKMQSEKEQ 691
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1170 MKHLVQALQASLEKEKEKVNSLKEqvaaakveaghNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHsQ 1249
Cdd:TIGR00618  692 LTYWKEMLAQCQTLLRELETHIEE-----------YDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKA-R 759
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1250 EIAQFQAELAEARAQLQllqkqldeqlskqpvgNQEMENLKWEVDQKEREIQSLKQQLDLTEQQGRKEL----------- 1318
Cdd:TIGR00618  760 TEAHFNNNEEVTAALQT----------------GAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIpsdedilnlqc 823
                          730
                   ....*....|....*
gi 1955007392 1319 EGLQQLLQNVKSELE 1333
Cdd:TIGR00618  824 ETLVQEEEQFLSRLE 838
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
833-1362 1.08e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 1.08e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  833 ALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVR 912
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE 315
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  913 QHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEM 992
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  993 KTkhkayenavgiLSRRLQEALAAKEAADAELGQLRAQGGSSDSSLALHER--IQALEAELQAVSHSKTLLEKELQEVIA 1070
Cdd:TIGR02168  396 AS-----------LNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELkeLQAELEELEEELEELQEELERLEEALE 464
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1071 LTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKL---ALELEHEKGKLTGLGQSNAALREHNSILETALAkrea 1147
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFsegVKALLKNQSGLSGILGVLSELISVDEGYEAAIE---- 540
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1148 dlVQLNLQVQAVLQRKEEEDRQmkhlvqALQASLEKEKEKVNSLKE------QVAAAKVEAGHNRRHFKAASLELSEVKK 1221
Cdd:TIGR02168  541 --AALGGRLQAVVVENLNAAKK------AIAFLKQNELGRVTFLPLdsikgtEIQGNDREILKNIEGFLGVAKDLVKFDP 612
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1222 ELQ-------AKEHLVQKLQaEADDLQIREGKH-------------------------------SQEIAQFQAELAEARA 1263
Cdd:TIGR02168  613 KLRkalsyllGGVLVVDDLD-NALELAKKLRPGyrivtldgdlvrpggvitggsaktnssilerRREIEELEEKIEELEE 691
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1264 QLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVK----------SELE 1333
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTeleaeieeleERLE 771
                          570       580
                   ....*....|....*....|....*....
gi 1955007392 1334 MAQEDLSMTQKDKFMLQAKVSELKNNMKT 1362
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKA 800
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
812-1339 1.56e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 69.32  E-value: 1.56e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  812 KLREELAIKSGQVEHLQQEtaalKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVH 891
Cdd:PRK03918   211 EISSELPELREELEKLEKE----VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK 286
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  892 GEKRTAEaELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEAR--- 968
Cdd:PRK03918   287 ELKEKAE-EYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHElye 365
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  969 --KAITEQKQKMRRLGSDLTSAQ-----KEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQGGSS---DSSL 1038
Cdd:PRK03918   366 eaKAKKEELERLKKRLTGLTPEKlekelEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCpvcGREL 445
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1039 ALHERIQALEAELQAVSHsktlLEKELQEVIALTSQELEESR--EKVLELEDELQESRGFRKKIKRLEESNKKLALE-LE 1115
Cdd:PRK03918   446 TEEHRKELLEEYTAELKR----IEKELKEIEEKERKLRKELRelEKVLKKESELIKLKELAEQLKELEEKLKKYNLEeLE 521
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1116 HEKGKLTGLGQSNAALREHNSILETALaKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKvnSLKEqv 1195
Cdd:PRK03918   522 KKAEEYEKLKEKLIKLKGEIKSLKKEL-EKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEE--RLKE-- 596
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1196 aaakVEAGHNRrhfkaaSLELSEVKKELQAKEHLVQKLQAEADdlqiregKHSQEIAQFQAELAEARAQLQLLqkqldeq 1275
Cdd:PRK03918   597 ----LEPFYNE------YLELKDAEKELEREEKELKKLEEELD-------KAFEELAETEKRLEELRKELEEL------- 652
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1955007392 1276 lsKQPVGNQEMENLKWEVDQKEREIQSLkqqldlteqqgRKELEGLQQLLQNVKSELEMAQEDL 1339
Cdd:PRK03918   653 --EKKYSEEEYEELREEYLELSRELAGL-----------RAELEELEKRREEIKKTLEKLKEEL 703
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
553-1244 6.73e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.45  E-value: 6.73e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  553 ERTTLTSKLKASQAEISSLQSVRQWYQQQlalaqeARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSQQLTETQHRSM 632
Cdd:pfam15921  279 EITGLTEKASSARSQANSIQSQLEIIQEQ------ARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLV 352
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  633 KEKGRIAAQLQgiEADMLDQEAAFMQIQEAKTMVeeDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQL 712
Cdd:pfam15921  353 LANSELTEART--ERDQFSQESGNLDDQLQKLLA--DLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEV 428
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  713 EALQQehldLMKqlTLTQEALQSREQSLDALQTHYDELQaRLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEEL 792
Cdd:pfam15921  429 QRLEA----LLK--AMKSECQGQMERQMAAIQGKNESLE-KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDL 501
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  793 DRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKK---QMQKIKEQFLQQKVMVEAYRRDATSKDQLISE- 868
Cdd:pfam15921  502 TASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNvqtECEALKLQMAEKDKVIEILRQQIENMTQLVGQh 581
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  869 ------LKATRKRLDSELKELRQELMQVHGEK-------RTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMeth 935
Cdd:pfam15921  582 grtagaMQVEKAQLEKEINDRRLELQEFKILKdkkdakiRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQL--- 658
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  936 LQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALA 1015
Cdd:pfam15921  659 LNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITA 738
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1016 AKEAADAELGQLR----AQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKELQeviALTSQElEESREKVLELEDELQ 1091
Cdd:pfam15921  739 KRGQIDALQSKIQfleeAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELE---VLRSQE-RRLKEKVANMEVALD 814
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1092 ESR----GFRKKIKRLEESNKKLALELEHEKGKLTGLG-QSNAALREHnsILETALAKREADLVQLNLQVQAVLQR---- 1162
Cdd:pfam15921  815 KASlqfaECQDIIQRQEQESVRLKLQHTLDVKELQGPGyTSNSSMKPR--LLQPASFTRTHSNVPSSQSTASFLSHhsrk 892
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1163 ----KEEEDRQMKHLVQALQASLEKEkEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEAD 1238
Cdd:pfam15921  893 tnalKEDPTRDLKQLLQELRSVINEE-PTVQLSKAEDKGRAPSLGALDDRVRDCIIESSLRSDICHSSSNSLQTEGSKSS 971

                   ....*.
gi 1955007392 1239 DLQIRE 1244
Cdd:pfam15921  972 ETCSRE 977
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1042-1340 1.29e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.63  E-value: 1.29e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1042 ERIQALEAELQ-----AVSHSKTLLEKELQEV---IALTSQELEESREKVLELEDELQESRGFRKKI-KRLEESNKKLAL 1112
Cdd:TIGR02169  211 ERYQALLKEKReyegyELLKEKEALERQKEAIerqLASLEEELEKLTEEISELEKRLEEIEQLLEELnKKIKDLGEEEQL 290
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1113 ELEHEKGKLTG-LGQSNAALREHNSILETAlakrEADLVQLNLQVQAVLQRKEEEDRQmkhlVQALQASLEKEKEKVNSL 1191
Cdd:TIGR02169  291 RVKEKIGELEAeIASLERSIAEKERELEDA----EERLAKLEAEIDKLLAEIEELERE----IEEERKRRDKLTEEYAEL 362
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1192 KEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELAEARAqlqllqkq 1271
Cdd:TIGR02169  363 KEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA-------- 434
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1955007392 1272 ldeqlsKQPVGNQEMENLKWEVDQKEREIQSLKQQLDlteqQGRKELEGLQQLLQNVKSELEMAQEDLS 1340
Cdd:TIGR02169  435 ------KINELEEEKEDKALEIKKQEWKLEQLAADLS----KYEQELYDLKEEYDRVEKELSKLQRELA 493
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
408-1110 1.85e-10

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 65.76  E-value: 1.85e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  408 LQVLKEKMRLEGQLEALSLEAS----------QALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVDTLKQSC 477
Cdd:TIGR00618  183 LMEFAKKKSLHGKAELLTLRSQlltlctpcmpDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLL 262
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  478 WDLERAMTDLQNMLEAknASLASSNNDLQVAEEQYQRLMAKVEdmqrsmlskdntvhDLRQQMTALQSQLQQVQLERTTL 557
Cdd:TIGR00618  263 KQLRARIEELRAQEAV--LEETQERINRARKAAPLAAHIKAVT--------------QIEQQAQRIHTELQSKMRSRAKL 326
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  558 TSKLKASQAEISSLQSVRQWYQQqlALAQEARVRLQGEmahiqvgqmTQAGLLEHlklenvsLSQQLTETQH-RSMKEKG 636
Cdd:TIGR00618  327 LMKRAAHVKQQSSIEEQRRLLQT--LHSQEIHIRDAHE---------VATSIREI-------SCQQHTLTQHiHTLQQQK 388
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  637 RIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQRmadSAASLEQQLEQVKLTLLQRDQQLEALQ 716
Cdd:TIGR00618  389 TTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQR---YAELCAAAITCTAQCEKLEKIHLQESA 465
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  717 QEhLDLMKQLTLTQEALQSREQSLDALQTHydelqaRLGELQGEAASREDTiCLLQNEKIILEAALQAAKSGKEELDRGA 796
Cdd:TIGR00618  466 QS-LKEREQQLQTKEQIHLQETRKKAVVLA------RLLELQEEPCPLCGS-CIHPNPARQDIDNPGPLTRRMQRGEQTY 537
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  797 RRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYR----RDATSKDQLISELKAT 872
Cdd:TIGR00618  538 AQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQdlteKLSEAEDMLACEQHAL 617
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  873 RKRLDSEL--KELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADL------EGHLQSAQKERDEMETHLQSLQFDKE 944
Cdd:TIGR00618  618 LRKLQPEQdlQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALsirvlpKELLASRQLALQKMQSEKEQLTYWKE 697
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  945 Q-------MVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYEN-------AVGILSRRL 1010
Cdd:TIGR00618  698 MlaqcqtlLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEahfnnneEVTAALQTG 777
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1011 QEALAAKEAADAELGQLRAQGGSSDSSLALHEriQALEAELQAVSHSKTLLEKELQEV---IALTSQELEESREKVLELE 1087
Cdd:TIGR00618  778 AELSHLAAEIQFFNRLREEDTHLLKTLEAEIG--QEIPSDEDILNLQCETLVQEEEQFlsrLEEKSATLGEITHQLLKYE 855
                          730       740
                   ....*....|....*....|...
gi 1955007392 1088 DELQESRGFRKKIKRLEESNKKL 1110
Cdd:TIGR00618  856 ECSKQLAQLTQEQAKIIQLSDKL 878
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
618-973 3.55e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 3.55e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  618 VSLSQQLTETQHR--SMK-EKGRIAAQLQGIEADMldqEAAFMQIQEAKTMVEEdLQRRLEEFEGERERLQRMAdsaASL 694
Cdd:TIGR02169  670 RSEPAELQRLRERleGLKrELSSLQSELRRIENRL---DELSQELSDASRKIGE-IEKEIEQLEQEEEKLKERL---EEL 742
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  695 EQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSL-----DALQTHYDELQARLGELQGEAASREDTIC 769
Cdd:TIGR02169  743 EEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLshsriPEIQAELSKLEEEVSRIEARLREIEQKLN 822
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  770 LLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQK 849
Cdd:TIGR02169  823 RLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELE 902
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  850 VMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHgEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKER 929
Cdd:TIGR02169  903 RKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDE-EIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEY 981
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 1955007392  930 DEMETHLQSLqfdKEQMVAVTEANEALKKQIEELQQEARKAITE 973
Cdd:TIGR02169  982 EEVLKRLDEL---KEKRAKLEEERKAILERIEEYEKKKREVFME 1022
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
464-1005 3.80e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.94  E-value: 3.80e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  464 DSLSSEVDTLKqscwDLERAMTDLQNMLEAknaslassnndLQVAEEQYQRLMAKVEDMQ-----RSMLSKDN---TVHD 535
Cdd:COG4913    228 DALVEHFDDLE----RAHEALEDAREQIEL-----------LEPIRELAERYAAARERLAeleylRAALRLWFaqrRLEL 292
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  536 LRQQMTALQSQLQQVQLERTTLTSKLKASQAEISSLQsvRQWYQ---QQLALAQEARVRLQGEMAHIQVGQMTQAGLLEH 612
Cdd:COG4913    293 LEAELEELRAELARLEAELERLEARLDALREELDELE--AQIRGnggDRLEQLEREIERLERELEERERRRARLEALLAA 370
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  613 LKLENVSLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKtmveEDLQRRLEEFEGERERL-QRMADSA 691
Cdd:COG4913    371 LGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRREL----RELEAEIASLERRKSNIpARLLALR 446
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  692 ASLEQQLE-------------QVK------------------LTLLQRDQQ----LEALQQEHLdlmkQLTLTQEALQSR 736
Cdd:COG4913    447 DALAEALGldeaelpfvgeliEVRpeeerwrgaiervlggfaLTLLVPPEHyaaaLRWVNRLHL----RGRLVYERVRTG 522
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  737 EQSLDALQTHYDELQARL--------GELQGEAASREDTIC------LLQNEKIILEAALQAAKSGKEELD--RGARRLE 800
Cdd:COG4913    523 LPDPERPRLDPDSLAGKLdfkphpfrAWLEAELGRRFDYVCvdspeeLRRHPRAITRAGQVKGNGTRHEKDdrRRIRSRY 602
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  801 EGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQF--LQQKVMVEAYRRDATSKDQLISELKATRKRLD- 877
Cdd:COG4913    603 VLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERReaLQRLAEYSWDEIDVASAEREIAELEAELERLDa 682
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  878 --SELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQS-LQFDKEQMVavteANE 954
Cdd:COG4913    683 ssDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERF----AAA 758
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1955007392  955 ALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGI 1005
Cdd:COG4913    759 LGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDA 809
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
669-1197 7.37e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 63.91  E-value: 7.37e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  669 DLQRRLEEFEGERERLQRMADSAASLEQQLEQvkltllqRDQQLEALQQEHLDLmkqltltQEALQSREQSLDALQTHYD 748
Cdd:PRK02224   217 ELDEEIERYEEQREQARETRDEADEVLEEHEE-------RREELETLEAEIEDL-------RETIAETEREREELAEEVR 282
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  749 ELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQ 828
Cdd:PRK02224   283 DLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELR 362
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  829 QETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREV 908
Cdd:PRK02224   363 EEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERV 442
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  909 AQVRQHMAdlEGHLQSAQKERDEMEtHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAiteqkqkmrrlgSDLTSA 988
Cdd:PRK02224   443 EEAEALLE--AGKCPECGQPVEGSP-HVETIEEDRERVEELEAELEDLEEEVEEVEERLERA------------EDLVEA 507
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  989 QKEMKTKHKAYENavgiLSRRLQEALAAKEAADAELGQLRAQGGSSDSSlALHERIQALEAELQAvshsktllEKELQEV 1068
Cdd:PRK02224   508 EDRIERLEERRED----LEELIAERRETIEEKRERAEELRERAAELEAE-AEEKREAAAEAEEEA--------EEAREEV 574
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1069 IALTS--QELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALRE--HNSILETALAK 1144
Cdd:PRK02224   575 AELNSklAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAefDEARIEEARED 654
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1955007392 1145 REaDLVQLNLQVQAVLQRKEEEdrqmKHLVQALQASLEKEKEKVNSLKEQVAA 1197
Cdd:PRK02224   655 KE-RAEEYLEQVEEKLDELREE----RDDLQAEIGAVENELEELEELRERREA 702
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
688-928 9.38e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 62.47  E-value: 9.38e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  688 ADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASredt 767
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE---- 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  768 icllqnekiiLEAALQAAksgKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQ 847
Cdd:COG4942     95 ----------LRAELEAQ---KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  848 QKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQK 927
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241

                   .
gi 1955007392  928 E 928
Cdd:COG4942    242 R 242
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
393-743 1.24e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.15  E-value: 1.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  393 SVSLESSAAETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVDT 472
Cdd:TIGR02168  665 SAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  473 LKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSkdntvhdLRQQMTALQSQLQQVQL 552
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA-------LREALDELRAELTLLNE 817
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  553 ERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSQQ--------- 623
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAlallrsele 897
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  624 -LTETQHRSMKEKGRIAAQLQG----IEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERL----QRMADSAASL 694
Cdd:TIGR02168  898 eLSEELRELESKRSELRRELEElrekLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIeddeEEARRRLKRL 977
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1955007392  695 EQQLEQ---VKLTLLqrdQQLEALQQEHLDLMKQLTLTQEALQSREQSLDAL 743
Cdd:TIGR02168  978 ENKIKElgpVNLAAI---EEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
818-1263 1.32e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 62.86  E-value: 1.32e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  818 AIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTA 897
Cdd:COG4717     42 FIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKL 121
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  898 EAELS--RLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLqfdkeqmvavteanEALKKQIEELQQEARKAITEQK 975
Cdd:COG4717    122 EKLLQllPLYQELEALEAELAELPERLEELEERLEELRELEEEL--------------EELEAELAELQEELEELLEQLS 187
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  976 QKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALA--AKEAADAELGQLRAQGGSSDSSLALHERIQALEAELQA 1053
Cdd:COG4717    188 LATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEelEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGS 267
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1054 VSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKI----KRLEESNKKLALELEHEKGKLTGLGQSNA 1129
Cdd:COG4717    268 LLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEeleeEELEELLAALGLPPDLSPEELLELLDRIE 347
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1130 ALREHNSILETalAKREADLVQLNLQVQAVLQRKEEEDRQMkhLVQALQAS--LEKEKEKVNSLKEQVAAAKVEAGHNRR 1207
Cdd:COG4717    348 ELQELLREAEE--LEEELQLEELEQEIAALLAEAGVEDEEE--LRAALEQAeeYQELKEELEELEEQLEELLGELEELLE 423
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1208 HFKAASL--ELSEVKKELQAKEHLVQKLQAEADDL--QIREGKHSQEIAQFQAELAEARA 1263
Cdd:COG4717    424 ALDEEELeeELEELEEELEELEEELEELREELAELeaELEQLEEDGELAELLQELEELKA 483
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
675-1357 1.88e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 1.88e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  675 EEFEGERERLQRMADSAaslEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLtQEALQSREQSLDALQthYDELQARL 754
Cdd:TIGR02169  166 AEFDRKKEKALEELEEV---EENIERLDLIIDEKRQQLERLRREREKAERYQAL-LKEKREYEGYELLKE--KEALERQK 239
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  755 GELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETsetlekLREELAIKSGQVEHLQQETAAL 834
Cdd:TIGR02169  240 EAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLR------VKEKIGELEAEIASLERSIAEK 313
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  835 KKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQH 914
Cdd:TIGR02169  314 ERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK 393
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  915 MADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEmkt 994
Cdd:TIGR02169  394 LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE--- 470
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  995 kHKAYENAVGILSRRLQealaakeaadaelgqlraqggssdsslALHERIQALEAELQAVSHS-------KTLLEKELQE 1067
Cdd:TIGR02169  471 -LYDLKEEYDRVEKELS---------------------------KLQRELAEAEAQARASEERvrggravEEVLKASIQG 522
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1068 VIALTSQELEESREKVLELEDELQESRGFrkkIKRLEESNKKLALEL--EHEKGKLT--GLGQSNAALREHNSILETALA 1143
Cdd:TIGR02169  523 VHGTVAQLGSVGERYATAIEVAAGNRLNN---VVVEDDAVAKEAIELlkRRKAGRATflPLNKMRDERRDLSILSEDGVI 599
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1144 KREADLVQLNLQVQA----------VLQRKEEEDRQMkhlVQALQASLEKEkekvnsLKEQVAAakVEAGHNRRhfKAAS 1213
Cdd:TIGR02169  600 GFAVDLVEFDPKYEPafkyvfgdtlVVEDIEAARRLM---GKYRMVTLEGE------LFEKSGA--MTGGSRAP--RGGI 666
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1214 LELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELAEARaqlqllqkqldeqlskqpvgnqemenlkwev 1293
Cdd:TIGR02169  667 LFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDAS------------------------------- 715
                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1955007392 1294 dQKEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELK 1357
Cdd:TIGR02169  716 -RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLE 778
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
695-1244 1.93e-09

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 62.50  E-value: 1.93e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  695 EQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSR-------EQSLDALQTHYDELQARLGELQGEAASREDT 767
Cdd:pfam01576   11 EEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAEtelcaeaEEMRARLAARKQELEEILHELESRLEEEEER 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  768 ICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQ 847
Cdd:pfam01576   91 SQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAE 170
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  848 QKVMVEAYRRDATSKDQLISELKATRKRLDselkELRQELMQVhgeKRTAEAELSRLHREVAQVRQHMADLEGHLqsaQK 927
Cdd:pfam01576  171 EEEKAKSLSKLKNKHEAMISDLEERLKKEE----KGRQELEKA---KRKLEGESTDLQEQIAELQAQIAELRAQL---AK 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  928 ERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQ--EARKAITEQKQKMRR-LGSDL-------------TSAQKE 991
Cdd:pfam01576  241 KEEELQAALARLEEETAQKNNALKKIRELEAQISELQEdlESERAARNKAEKQRRdLGEELealkteledtldtTAAQQE 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  992 MKTKHkayENAVGILSRRLQEALAAKEAADAELGQLRAQGGSSdsslaLHERIQALEAELQAVSHSKTLLEKE---LQEV 1068
Cdd:pfam01576  321 LRSKR---EQEVTELKKALEEETRSHEAQLQEMRQKHTQALEE-----LTEQLEQAKRNKANLEKAKQALESEnaeLQAE 392
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1069 IALTSQELEESREKVLELEDELQE-----SRGFRKKIKRLEESNkKLALELEHEKGKLtglgqsnaalrehnSILETALA 1143
Cdd:pfam01576  393 LRTLQQAKQDSEHKRKKLEGQLQElqarlSESERQRAELAEKLS-KLQSELESVSSLL--------------NEAEGKNI 457
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1144 KREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQAsLEKEKekvNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKEL 1223
Cdd:pfam01576  458 KLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQ-LEDER---NSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKL 533
                          570       580
                   ....*....|....*....|....*...
gi 1955007392 1224 Q-------AKEHLVQKLQAEADDLQIRE 1244
Cdd:pfam01576  534 EedagtleALEEGKKRLQRELEALTQQL 561
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
829-1343 2.43e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 62.44  E-value: 2.43e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  829 QETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLH--- 905
Cdd:pfam15921  138 QSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHfrs 217
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  906 -------------REVAQVRQHMADLEGHLQSAQKE-RDEMETHLQSLQFDKEQMV----------------AVTEANeA 955
Cdd:pfam15921  218 lgsaiskilreldTEISYLKGRIFPVEDQLEALKSEsQNKIELLLQQHQDRIEQLIseheveitgltekassARSQAN-S 296
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  956 LKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQGGSSD 1035
Cdd:pfam15921  297 IQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLD 376
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1036 SSLA-----LHERIQALEAELQ--------------AVSHSKTLLEKELQEVIALTS--------------------QEL 1076
Cdd:pfam15921  377 DQLQklladLHKREKELSLEKEqnkrlwdrdtgnsiTIDHLRRELDDRNMEVQRLEAllkamksecqgqmerqmaaiQGK 456
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1077 EESREKVLELEDELQESRGFRKKIKRlEESNKKLALELEHEKgkltgLGQSNAALREHNSILETALAKREADLVQLNLQV 1156
Cdd:pfam15921  457 NESLEKVSSLTAQLESTKEMLRKVVE-ELTAKKMTLESSERT-----VSDLTASLQEKERAIEATNAEITKLRSRVDLKL 530
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1157 QAVLQRKEEED--RQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKehlvqklQ 1234
Cdd:pfam15921  531 QELQHLKNEGDhlRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDR-------R 603
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1235 AEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLDLTEQQG 1314
Cdd:pfam15921  604 LELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNF 683
                          570       580
                   ....*....|....*....|....*....
gi 1955007392 1315 RKELEGLQQLLQNVKSELEMAQEDLSMTQ 1343
Cdd:pfam15921  684 RNKSEEMETTTNKLKMQLKSAQSELEQTR 712
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
787-1115 3.04e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.01  E-value: 3.04e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  787 SGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETA-ALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQL 865
Cdd:TIGR02169  163 AGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREkAERYQALLKEKREYEGYELLKEKEALERQKEAI 242
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  866 ---ISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRL-HREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQ- 940
Cdd:TIGR02169  243 erqLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEe 322
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  941 ---FDKEQMVAVTEANEALKKQIEELQQEARK---AITEQKQKMRRLGSDLTSAQKEMKT---KHKAYENAVGILSRRLQ 1011
Cdd:TIGR02169  323 rlaKLEAEIDKLLAEIEELEREIEEERKRRDKlteEYAELKEELEDLRAELEEVDKEFAEtrdELKDYREKLEKLKREIN 402
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1012 EALAAKEAADAELGQLRAQGGSsdsslaLHERIQALEAELQAVSHSKtlleKELQEVIALTSQELEESREKvleLEDELQ 1091
Cdd:TIGR02169  403 ELKRELDRLQEELQRLSEELAD------LNAAIAGIEAKINELEEEK----EDKALEIKKQEWKLEQLAAD---LSKYEQ 469
                          330       340
                   ....*....|....*....|....
gi 1955007392 1092 ESRGFRKKIKRLEESNKKLALELE 1115
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELA 493
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
660-1362 3.73e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.53  E-value: 3.73e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  660 QEAKTMVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQS 739
Cdd:pfam02463  224 EYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELL 303
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  740 LDALQTHYD-----ELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRgaRRLEEGTEETSETLEKLR 814
Cdd:pfam02463  304 KLERRKVDDeeklkESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEK--LQEKLEQLEEELLAKKKL 381
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  815 EELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATR--KRLDSELKELRQELMQVHG 892
Cdd:pfam02463  382 ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIElkQGKLTEEKEELEKQELKLL 461
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  893 EKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSL-------------------------------QF 941
Cdd:pfam02463  462 KDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGlkvllalikdgvggriisahgrlgdlgvaveNY 541
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  942 DKEQMVAVTEANEALKKQIEElQQEARKAITEQKQKMRRLGSDLTSAQKEMKtkhKAYENAVGILSRRLQEALAAKEAAD 1021
Cdd:pfam02463  542 KVAISTAVIVEVSATADEVEE-RQKLVRALTELPLGARKLRLLIPKLKLPLK---SIAVLEIDPILNLAQLDKATLEADE 617
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1022 AELGQLRAQGGSSDSSLA-LHERIQALEAELQAVShSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKI 1100
Cdd:pfam02463  618 DDKRAKVVEGILKDTELTkLKESAKAKESGLRKGV-SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1101 KRLEESNKKLALELEHEKGKLTGLGQSNAALRE--HNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQ 1178
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQEaqDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1179 ASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKhsqEIAQFQAEL 1258
Cdd:pfam02463  777 AEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKE---EQKLEKLAE 853
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1259 AEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQED 1338
Cdd:pfam02463  854 EELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKY 933
                          730       740
                   ....*....|....*....|....
gi 1955007392 1339 LSMTQKDKFMLQAKVSELKNNMKT 1362
Cdd:pfam02463  934 EEEPEELLLEEADEKEKEENNKEE 957
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
812-1337 2.26e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 58.88  E-value: 2.26e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  812 KLREELAIKSGQVEHLQQETAALKKQMQKIKEQflQQKVMVEayrrdatskdqlISELKATRKRLDSELKELRQELMQVH 891
Cdd:TIGR04523  107 KINSEIKNDKEQKNKLEVELNKLEKQKKENKKN--IDKFLTE------------IKKKEKELEKLNNKYNDLKKQKEELE 172
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  892 GEKRTAEAELSRLHREVAQVRQHMADLEgHLQSAQKERDEMETHLQSlqfdkeQMVAVTEANEALKKQIEELQQEARK-- 969
Cdd:TIGR04523  173 NELNLLEKEKLNIQKNIDKIKNKLLKLE-LLLSNLKKKIQKNKSLES------QISELKKQNNQLKDNIEKKQQEINEkt 245
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  970 -AITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSrRLQEALAAKEAADAELGQLRAQGGSSDsslaLHERIQALE 1048
Cdd:TIGR04523  246 tEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIK-ELEKQLNQLKSEISDLNNQKEQDWNKE----LKSELKNQE 320
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1049 AELQAVSHSKTLLEK---ELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKG----KL 1121
Cdd:TIGR04523  321 KKLEEIQNQISQNNKiisQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINdlesKI 400
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1122 TGLGQSNAALREHNSILET---ALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAA 1198
Cdd:TIGR04523  401 QNQEKLNQQKDEQIKKLQQekeLLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKI 480
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1199 KVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSK 1278
Cdd:TIGR04523  481 KQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLE 560
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1955007392 1279 QPVG--NQEMENLKWE---VDQKEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQE 1337
Cdd:TIGR04523  561 KEIDekNKEIEELKQTqksLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKK 624
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
683-1340 3.30e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 58.70  E-value: 3.30e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  683 RLQRMADSAASLEQQLEQVKLTLLQrdqqleaLQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEaa 762
Cdd:pfam12128  235 GIMKIRPEFTKLQQEFNTLESAELR-------LSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDE-- 305
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  763 sredticlLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEklrEELAIKSGQVEHLQQETAALKKQMQKIK 842
Cdd:pfam12128  306 --------LNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQ---EQLPSWQSELENLEERLKALTGKHQDVT 374
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  843 EQFLQQKVMVEayRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTA-EAELSRLHREVAQVRQHMADLEGH 921
Cdd:pfam12128  375 AKYNRRRSKIK--EQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQlEAGKLEFNEEEYRLKSRLGELKLR 452
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  922 LQSAQKERDEMethLQSLQFDkEQMVAVTEANEALKKQIEELQQE---ARKAITEQKQKMRRLGSDLTSAQKEMKTKHKA 998
Cdd:pfam12128  453 LNQATATPELL---LQLENFD-ERIERAREEQEAANAEVERLQSElrqARKRRDQASEALRQASRRLEERQSALDELELQ 528
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  999 YENAVGILsrrLQEALAAKEAADAELGQL--RAQGGSSD-------SSLALHERIQALEAELQAVSHSKTL-LEKELQEV 1068
Cdd:pfam12128  529 LFPQAGTL---LHFLRKEAPDWEQSIGKVisPELLHRTDldpevwdGSVGGELNLYGVKLDLKRIDVPEWAaSEEELRER 605
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1069 IALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQS-----NAALREHNSILETALA 1143
Cdd:pfam12128  606 LDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSekdkkNKALAERKDSANERLN 685
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1144 KREADLVQLNLQVQAVLQRKEEEDRQMK-HLVQALQASLEKEKEKVNSLKEQVAAAKVEAghnRRHFKAASlelSEVKKE 1222
Cdd:pfam12128  686 SLEAQLKQLDKKHQAWLEEQKEQKREARtEKQAYWQVVEGALDAQLALLKAAIAARRSGA---KAELKALE---TWYKRD 759
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1223 LQAKehlvqklqaeaDDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPvgnQEMENLKWEVDQKEREIQS 1302
Cdd:pfam12128  760 LASL-----------GVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWL---QRRPRLATQLSNIERAISE 825
                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 1955007392 1303 LKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDLS 1340
Cdd:pfam12128  826 LQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLR 863
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
637-1114 3.56e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.51  E-value: 3.56e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  637 RIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQ 716
Cdd:PRK02224   311 AVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELE 390
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  717 QEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTIcllqNEKIILEAALQAAKSGKEELDRGa 796
Cdd:PRK02224   391 EEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERV----EEAEALLEAGKCPECGQPVEGSP- 465
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  797 rrleegteetsetlekLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKD------QLISELK 870
Cdd:PRK02224   466 ----------------HVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEErredleELIAERR 529
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  871 ATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMEThlqslqfdkeqMVAVT 950
Cdd:PRK02224   530 ETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER-----------IRTLL 598
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  951 EANEALKKQIEELQqEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKayENAVGILSRRLQEALAAKEAADAELGQLRAQ 1030
Cdd:PRK02224   599 AAIADAEDEIERLR-EKREALAELNDERRERLAEKRERKRELEAEFD--EARIEEAREDKERAEEYLEQVEEKLDELREE 675
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1031 GGSsdsslaLHERIQALEAELQavshsktllekelqevialtsqELEESREKVLELEDELQESRGFRKKIKRLEESNKKL 1110
Cdd:PRK02224   676 RDD------LQAEIGAVENELE----------------------ELEELRERREALENRVEALEALYDEAEELESMYGDL 727

                   ....
gi 1955007392 1111 ALEL 1114
Cdd:PRK02224   728 RAEL 731
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
404-1241 4.39e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 58.26  E-value: 4.39e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  404 QEEMLQVLKEK-MRLEGQLEALSLEASQALKEKAELQAQLAA--------------LSTKLQAQVECSHSSQQRQDSLSS 468
Cdd:pfam01576   10 KEEELQKVKERqQKAESELKELEKKHQQLCEEKNALQEQLQAetelcaeaeemrarLAARKQELEEILHELESRLEEEEE 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  469 EVDTLKQSCWDLERAMTDLQNMLEAKNAslasSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQM---TALQS 545
Cdd:pfam01576   90 RSQQLQNEKKKMQQHIQDLEEQLDEEEA----ARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLeerISEFT 165
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  546 QLQQVQLERTTLTSKLKASQ-AEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSQQL 624
Cdd:pfam01576  166 SNLAEEEEKAKSLSKLKNKHeAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEEL 245
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  625 TETQHRSMKEKGRIAAQLQGI---EADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQRMADSAASL------- 694
Cdd:pfam01576  246 QAALARLEEETAQKNNALKKIrelEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTAAQqelrskr 325
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  695 EQQLEQVKLTLLQR----DQQLEALQQEHL----DLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREd 766
Cdd:pfam01576  326 EQEVTELKKALEEEtrshEAQLQEMRQKHTqaleELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSE- 404
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  767 ticllqNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFl 846
Cdd:pfam01576  405 ------HKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELL- 477
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  847 qqkvmveayRRDATSKDQLISELKAtrkrLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQ 926
Cdd:pfam01576  478 ---------QEETRQKLNLSTRLRQ----LEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALE 544
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  927 KERDEMETHLQSLqfdKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKmRRLGSDLTSAQKEMKtKHKAYENAVG-- 1004
Cdd:pfam01576  545 EGKKRLQRELEAL---TQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQ-RQLVSNLEKKQKKFD-QMLAEEKAISar 619
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1005 ILSRRLQEALAAKEAADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEK---ELQEVIALTSQELEESRE 1081
Cdd:pfam01576  620 YAEERDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKnvhELERSKRALEQQVEEMKT 699
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1082 KVLELEDELQESRGFRkkiKRLEESNKKLALELEHEKGKLTGLG-----QSNAALREHNSILE----------TALAKRE 1146
Cdd:pfam01576  700 QLEELEDELQATEDAK---LRLEVNMQALKAQFERDLQARDEQGeekrrQLVKQVRELEAELEderkqraqavAAKKKLE 776
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1147 ADLVQLNLQVQAVLQRKEEEDRQMKHLvQALQASLEKEKEKVNSLKEQVAAAKVEaghNRRHFKAASLELSEVKKELQAK 1226
Cdd:pfam01576  777 LDLKELEAQIDAANKGREEAVKQLKKL-QAQMKDLQRELEEARASRDEILAQSKE---SEKKLKNLEAELLQLQEDLAAS 852
                          890
                   ....*....|....*
gi 1955007392 1227 EHLVQKLQAEADDLQ 1241
Cdd:pfam01576  853 ERARRQAQQERDELA 867
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
871-1359 9.21e-08

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 56.67  E-value: 9.21e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  871 ATRKRLDSELKELRQELMQVHGEKRTAEAELSR----LHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQM 946
Cdd:pfam05557    2 AELIESKARLSQLQNEKKQMELEHKRARIELEKkasaLKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLK 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  947 VAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYEnavgilsrRLQEALAAKEAADAELGQ 1026
Cdd:pfam05557   82 KKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELE--------ELQERLDLLKAKASEAEQ 153
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1027 LRAQGGSSDSSLALHE-RIQALEAELQAVSHSKTLLEKELQEVIALTSQE------------LEESREKVLELEDELQes 1093
Cdd:pfam05557  154 LRQNLEKQQSSLAEAEqRIKELEFEIQSQEQDSEIVKNSKSELARIPELEkelerlrehnkhLNENIENKLLLKEEVE-- 231
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1094 rGFRKKIKRLEESNKKLA---LELEHEKGKLTG---LGQSNA-------ALREHNSIL---ETALAKREADLVQLNLQVQ 1157
Cdd:pfam05557  232 -DLKRKLEREEKYREEAAtleLEKEKLEQELQSwvkLAQDTGlnlrspeDLSRRIEQLqqrEIVLKEENSSLTSSARQLE 310
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1158 AVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEaghnrRHFKAASLElsEVKKELQAKEHLVQKLQaea 1237
Cdd:pfam05557  311 KARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKE-----RDGYRAILE--SYDKELTMSNYSPQLLE--- 380
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1238 ddlqiREGKHSQEIAQFQAELAEARAQLQllqkqldeqlskqpVGNQEMENLKWEVDQKEREIQSLKQQLDLTEQQG--- 1314
Cdd:pfam05557  381 -----RIEEAEDMTQKMQAHNEEMEAQLS--------------VAEEELGGYKQQAQTLERELQALRQQESLADPSYske 441
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1955007392 1315 -----RKELEGLQ---QLLQNVKSELEMAQEDLSMtQKDKFMLQAKVSELKNN 1359
Cdd:pfam05557  442 evdslRRKLETLElerQRLREQKNELEMELERRCL-QGDYDPKKTKVLHLSMN 493
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
402-1003 1.09e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.85  E-value: 1.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  402 ETQEEMLQVLKEKMRLEgQLEALSLEASQALKEKAELQAQLAALstKLQAQVECSHSSQQRQDSLSSEVDTLKQSCWDLE 481
Cdd:COG4913    239 RAHEALEDAREQIELLE-PIRELAERYAAARERLAELEYLRAAL--RLWFAQRRLELLEAELEELRAELARLEAELERLE 315
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  482 RAMTDLQNML-EAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRsmlskdntvhDLRQQMTALQSQLQQVQLERTTLTSK 560
Cdd:COG4913    316 ARLDALREELdELEAQIRGNGGDRLEQLEREIERLERELEERER----------RRARLEALLAALGLPLPASAEEFAAL 385
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  561 LKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAhiqvgqmtqagllehlklenvSLSQQLTETQHRsmkeKGRIAA 640
Cdd:COG4913    386 RAEAAALLEALEEELEALEEALAEAEAALRDLRRELR---------------------ELEAEIASLERR----KSNIPA 440
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  641 QLQgieaDMLDQeaafmqIQEAKTMVEEDLQrrleeFEGE------RERLQRMAdsaasLEQQLEQVKLTLLQRDQQLEA 714
Cdd:COG4913    441 RLL----ALRDA------LAEALGLDEAELP-----FVGElievrpEEERWRGA-----IERVLGGFALTLLVPPEHYAA 500
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  715 LQQ--EHLDLMKQLTLtqEALQSREQSLDALQTHYDELQARL--------GELQGEAASREDTICL-----LQNEkiilE 779
Cdd:COG4913    501 ALRwvNRLHLRGRLVY--ERVRTGLPDPERPRLDPDSLAGKLdfkphpfrAWLEAELGRRFDYVCVdspeeLRRH----P 574
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  780 AALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDA 859
Cdd:COG4913    575 RAITRAGQVKGNGTRHEKDDRRRIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLA 654
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  860 TSKDQLIsELKATRKRLDselkELRQELMQVhgekRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSL 939
Cdd:COG4913    655 EYSWDEI-DVASAEREIA----ELEAELERL----DASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQA 725
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1955007392  940 QFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAV 1003
Cdd:COG4913    726 EEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEEL 789
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
565-1191 1.12e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.85  E-value: 1.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  565 QAEISSLQSVRQWYQQQLALAQEARV-RLQGEMAHIQVGQMTQAGL---LEHLKLENVSLSQQLTETQhrsmKEKGRIAA 640
Cdd:COG4913    248 REQIELLEPIRELAERYAAARERLAElEYLRAALRLWFAQRRLELLeaeLEELRAELARLEAELERLE----ARLDALRE 323
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  641 QLQGIEAdmldqeaafmQIQEAKTMVEEDLQRRLEEFEGERERLQRmadSAASLEQQLEQVKLTLLQRDQQLEALQQEHl 720
Cdd:COG4913    324 ELDELEA----------QIRGNGGDRLEQLEREIERLERELEERER---RRARLEALLAALGLPLPASAEEFAALRAEA- 389
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  721 dlmkqltltQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKsgkeeldrgarrle 800
Cdd:COG4913    390 ---------AALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALR-------------- 446
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  801 egteetsetlEKLREELAIKSGQV-----------------------------------EHLQQETAALKKQMQKIKEQF 845
Cdd:COG4913    447 ----------DALAEALGLDEAELpfvgelievrpeeerwrgaiervlggfaltllvppEHYAAALRWVNRLHLRGRLVY 516
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  846 LQQKVMVEAYRRDATSKDQLISELKAT----RKRLDSEL------------KELRQELM------QVHGEKR-------- 895
Cdd:COG4913    517 ERVRTGLPDPERPRLDPDSLAGKLDFKphpfRAWLEAELgrrfdyvcvdspEELRRHPRaitragQVKGNGTrhekddrr 596
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  896 ----------TAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQfdkeqmvAVTEANEALKKqIEELQQ 965
Cdd:COG4913    597 rirsryvlgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQ-------RLAEYSWDEID-VASAER 668
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  966 EARkAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAvgilsrrlqealaakeaaDAELGQLRAQGGssdsslALHERIQ 1045
Cdd:COG4913    669 EIA-ELEAELERLDASSDDLAALEEQLEELEAELEEL------------------EEELDELKGEIG------RLEKELE 723
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1046 ALEAELQAVshsKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELE--------HE 1117
Cdd:COG4913    724 QAEEELDEL---QDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELEramrafnrEW 800
                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1955007392 1118 KGKLTGLGQSNAALRE----HNSILETALAKREADLVQLnlqvqavlqRKEEEDRQMKHLVQALQASLEKEKEKVNSL 1191
Cdd:COG4913    801 PAETADLDADLESLPEylalLDRLEEDGLPEYEERFKEL---------LNENSIEFVADLLSKLRRAIREIKERIDPL 869
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
775-1361 1.13e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.90  E-value: 1.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  775 KIILEAAlqaakSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKE----------- 843
Cdd:pfam02463  156 LEIEEEA-----AGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLeleeeyllyld 230
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  844 ---------QFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQ- 913
Cdd:pfam02463  231 ylklneeriDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKv 310
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  914 --------HMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDL 985
Cdd:pfam02463  311 ddeeklkeSEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAA 390
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  986 TSAQKEMKTKHKAyENAVGILSRRLQEALAAKEAADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKEL 1065
Cdd:pfam02463  391 KLKEEELELKSEE-EKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKK 469
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1066 QEVIALTSQELEESREKVLELEDELQESRGFRKKIKRlEESNKKLALELEHEKGKLTGLGQSNAALREhnsILETALAKR 1145
Cdd:pfam02463  470 SEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKAR-SGLKVLLALIKDGVGGRIISAHGRLGDLGV---AVENYKVAI 545
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1146 E-ADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVN---SLKEQVAAAKVEAGHNRRHFKAASLELSEVKK 1221
Cdd:pfam02463  546 StAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPlksIAVLEIDPILNLAQLDKATLEADEDDKRAKVV 625
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1222 ELQAKEHLVQKLQAEADDLQIREGK-HSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREI 1300
Cdd:pfam02463  626 EGILKDTELTKLKESAKAKESGLRKgVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKE 705
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1955007392 1301 QSLKQQLDLTEQQGRKELEGLQQLLQNV--------KSELEMAQEDLSMTQKDKFMLQAKVSELKNNMK 1361
Cdd:pfam02463  706 QREKEELKKLKLEAEELLADRVQEAQDKineelkllKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEK 774
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
510-1260 1.13e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 56.90  E-value: 1.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  510 EQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEAR 589
Cdd:TIGR00618  176 DQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQ 255
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  590 VRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSQQltetqhrsmKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEED 669
Cdd:TIGR00618  256 LKKQQLLKQLRARIEELRAQEAVLEETQERINRA---------RKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKL 326
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  670 LQRRLE------EFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHlDLMKQLTLTQEALQSREQSLDAL 743
Cdd:TIGR00618  327 LMKRAAhvkqqsSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIH-TLQQQKTTLTQKLQSLCKELDIL 405
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  744 QthydelqarlgELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGArrleegteetsetleklREELAIKSGQ 823
Cdd:TIGR00618  406 Q-----------REQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAI-----------------TCTAQCEKLE 457
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  824 VEHLQQETAALKKQMQKIKeqflQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVhGEKRTAEAELSR 903
Cdd:TIGR00618  458 KIHLQESAQSLKEREQQLQ----TKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDI-DNPGPLTRRMQR 532
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  904 LHREVAQVRQHMADLEGHLQSAQKER----DEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMr 979
Cdd:TIGR00618  533 GEQTYAQLETSEEDVYHQLTSERKQRaslkEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLA- 611
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  980 rlgsdLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQGGSSDSSLalheRIQALEAELQAVSHSKT 1059
Cdd:TIGR00618  612 -----CEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHAL----SIRVLPKELLASRQLAL 682
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1060 LLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKlalELEHEKGKLtglgqsNAALREHNSILE 1139
Cdd:TIGR00618  683 QKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGS---DLAAREDAL------NQSLKELMHQAR 753
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1140 TALAKREADLVQLNLQVQAVLQRkeeeDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEV 1219
Cdd:TIGR00618  754 TVLKARTEAHFNNNEEVTAALQT----GAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQE 829
                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 1955007392 1220 KKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELAE 1260
Cdd:TIGR00618  830 EEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAK 870
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
569-987 1.32e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.50  E-value: 1.32e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  569 SSLQSVRQWY--QQQLALAQEARVRLQGEMAHIQVGQmtqagllEHLKLENVSLSQQLTETQHrSMKEKGRIAAQLQGIE 646
Cdd:COG3096    286 RALELRRELFgaRRQLAEEQYRLVEMARELEELSARE-------SDLEQDYQAASDHLNLVQT-ALRQQEKIERYQEDLE 357
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  647 ADMLDQEAAFMQIQEAktmvEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQehldlmkql 726
Cdd:COG3096    358 ELTERLEEQEEVVEEA----AEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEK--------- 424
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  727 tlTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGArrleegteET 806
Cdd:COG3096    425 --ARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERSQ--------AW 494
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  807 SETLEKLRE--ELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQL---ISELKATRKRLDSELK 881
Cdd:COG3096    495 QTARELLRRyrSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELeelLAELEAQLEELEEQAA 574
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  882 ELRQELMQVHGEKRTAEAELSRLH------REVAQVRQHMADLEG-HLQSAQKERDEMET---HLQSLQFDKEQMVavtE 951
Cdd:COG3096    575 EAVEQRSELRQQLEQLRARIKELAarapawLAAQDALERLREQSGeALADSQEVTAAMQQlleREREATVERDELA---A 651
                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 1955007392  952 ANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTS 987
Cdd:COG3096    652 RKQALESQIERLSQPGGAEDPRLLALAERLGGVLLS 687
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
400-1262 2.14e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 55.82  E-value: 2.14e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  400 AAETQEEMLQVLKEKMRlEGQLEAlsleasQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDSlssEVDTLKQSCWD 479
Cdd:TIGR00606  187 ALETLRQVRQTQGQKVQ-EHQMEL------KYLKQYKEKACEIRDQITSKEAQLESSREIVKSYEN---ELDPLKNRLKE 256
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  480 LERAMTDLQNmLEAKNASLASSNNDLQVAEEQYQRLMAKV-----EDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLER 554
Cdd:TIGR00606  257 IEHNLSKIMK-LDNEIKALKSRKKQMEKDNSELELKMEKVfqgtdEQLNDLYHNHQRTVREKERELVDCQRELEKLNKER 335
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  555 TTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMahiqvgqmtQAGLLEHLKLENVSLSQQLTETQHRSMKE 634
Cdd:TIGR00606  336 RLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRL---------ELDGFERGPFSERQIKNFHTLVIERQEDE 406
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  635 KGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQRMADSAasleQQLEQVKLTLLQRDQQLEA 714
Cdd:TIGR00606  407 AKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKEL----QQLEGSSDRILELDQELRK 482
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  715 LQQEhLDLMKQLTLTqEALQSREQSLDALQTHYDE----LQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKE 790
Cdd:TIGR00606  483 AERE-LSKAEKNSLT-ETLKKEVKSLQNEKADLDRklrkLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSD 560
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  791 ELDRGA------RRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQqkvmVEAYRRDATSKDQ 864
Cdd:TIGR00606  561 ELTSLLgyfpnkKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSS----YEDKLFDVCGSQD 636
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  865 LISELKATRKRLDSELKEL----------RQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMET 934
Cdd:TIGR00606  637 EESDLERLKEEIEKSSKQRamlagatavySQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTES 716
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  935 HLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRR--LQE 1012
Cdd:TIGR00606  717 ELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVtiMER 796
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1013 ALAAKEAADAELGQLRAQGGSSDSSLA---LHERIQALEAELQAVSHSKTLLEK---ELQEVIALTSQELEESREKVLEL 1086
Cdd:TIGR00606  797 FQMELKDVERKIAQQAAKLQGSDLDRTvqqVNQEKQEKQHELDTVVSKIELNRKliqDQQEQIQHLKSKTNELKSEKLQI 876
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1087 EDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALREHNsilETALAKREADLVQLNLQVQAVLQRKEEE 1166
Cdd:TIGR00606  877 GTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEK---EELISSKETSNKKAQDKVNDIKEKVKNI 953
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1167 DRQMKHLVQALQASLEKE-KEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREG 1245
Cdd:TIGR00606  954 HGYMKDIENKIQDGKDDYlKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEV 1033
                          890
                   ....*....|....*..
gi 1955007392 1246 KhsQEIAQFQAELAEAR 1262
Cdd:TIGR00606 1034 E--EELKQHLKEMGQMQ 1048
PRK11281 PRK11281
mechanosensitive channel MscK;
832-1181 2.69e-07

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 55.69  E-value: 2.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  832 AALKKQMQKIKEQFLQQKVmveayrrDATSKDQLISELK--ATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHRE-V 908
Cdd:PRK11281    39 ADVQAQLDALNKQKLLEAE-------DKLVQQDLEQTLAllDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDnD 111
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  909 AQVRQHMADLEghLQSAQKERDEMETHLQSLQfdkeqmVAVTEANEALkkqieelqqearkaITEQKQKMRrlgsdltsA 988
Cdd:PRK11281   112 EETRETLSTLS--LRQLESRLAQTLDQLQNAQ------NDLAEYNSQL--------------VSLQTQPER--------A 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  989 QKEMktkhkaYENavgilSRRLQealaakeaadaelgQLRAQ-GGSSDSSLAL-HERIQALEAELQAVSHSKTLLEKELQ 1066
Cdd:PRK11281   162 QAAL------YAN-----SQRLQ--------------QIRNLlKGGKVGGKALrPSQRVLLQAEQALLNAQNDLQRKSLE 216
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1067 ---EVIALTSQELEESREKVLELEDELQESRGFRKKiKRLEESNKKLAlelEHEKGKLTGLGQSNAALR---EHNSILET 1140
Cdd:PRK11281   217 gntQLQDLLQKQRDYLTARIQRLEHQLQLLQEAINS-KRLTLSEKTVQ---EAQSQDEAARIQANPLVAqelEINLQLSQ 292
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 1955007392 1141 ALAK---READLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASL 1181
Cdd:PRK11281   293 RLLKateKLNTLTQQNLRVKNWLDRLTQSERNIKEQISVLKGSL 336
PRK01156 PRK01156
chromosome segregation protein; Provisional
730-1305 3.35e-07

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 55.29  E-value: 3.35e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  730 QEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRgarRLEEGTEETSET 809
Cdd:PRK01156   189 EEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNR---YESEIKTAESDL 265
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  810 LEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFlqqkvmveAYRRDATSKDQLISELKATRKRLDSELKELrQELMQ 889
Cdd:PRK01156   266 SMELEKNNYYKELEERHMKIINDPVYKNRNYINDYF--------KYKNDIENKKQILSNIDAEINKYHAIIKKL-SVLQK 336
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  890 VHGEKRTAEAELSRLHREVAQVRQHMADLEGHL---QSAQKERDEMETHLQSLQFDKEQMVAVTEAN-EALKKQIEELqq 965
Cdd:PRK01156   337 DYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLksiESLKKKIEEYSKNIERMSAFISEILKIQEIDpDAIKKELNEI-- 414
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  966 eaRKAITEQKQKMrrlgSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQGGSSDSSLalHERIQ 1045
Cdd:PRK01156   415 --NVKLQDISSKV----SSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSNHIINHYNEKKSRL--EEKIR 486
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1046 ALEAELQAVSHSKTLLEKELQEviaLTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKlalelehekgkltglg 1125
Cdd:PRK01156   487 EIEIEVKDIDEKIVDLKKRKEY---LESEEINKSINEYNKIESARADLEDIKIKINELKDKHDK---------------- 547
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1126 qSNAALREHNSI-LETALAKRE----ADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQaSLEKEKEKVNSLKEQVAAAKV 1200
Cdd:PRK01156   548 -YEEIKNRYKSLkLEDLDSKRTswlnALAVISLIDIETNRSRSNEIKKQLNDLESRLQ-EIEIGFPDDKSYIDKSIREIE 625
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1201 EAGHNrrhfkaasleLSEVKKELQAKEHLVQKLQ----------AEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQK 1270
Cdd:PRK01156   626 NEANN----------LNNKYNEIQENKILIEKLRgkidnykkqiAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKA 695
                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1955007392 1271 QLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQ 1305
Cdd:PRK01156   696 NRARLESTIEILRTRINELSDRINDINETLESMKK 730
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
535-765 3.42e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.38  E-value: 3.42e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  535 DLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQvgqmtqagllEHLK 614
Cdd:COG4942     31 QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR----------AELE 100
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  615 LENVSLSQQLTETQhrSMKEKGRIAAQLQGieADMLDQEAAFMQIQEaktmVEEDLQRRLEEFEGERERLQRMADSAASL 694
Cdd:COG4942    101 AQKEELAELLRALY--RLGRQPPLALLLSP--EDFLDAVRRLQYLKY----LAPARREQAEELRADLAELAALRAELEAE 172
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1955007392  695 EQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLtltQEALQSREQSLDALQTHYDELQARLGELQGEAASRE 765
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLLARL---EKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
633-1113 4.13e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.68  E-value: 4.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  633 KEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEdLQRRLEEFEGERERLQRmadsAASLEQQLEQVKLTLlqRDQQL 712
Cdd:PRK03918   314 KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKE-LEKRLEELEERHELYEE----AKAKKEELERLKKRL--TGLTP 386
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  713 EALQQEHLDLMKQLTLTQEALqsreqsldalqthyDELQARLGELQGEAASREDTIcllqnekIILEAALQAAKSGKEEL 792
Cdd:PRK03918   387 EKLEKELEELEKAKEEIEEEI--------------SKITARIGELKKEIKELKKAI-------EELKKAKGKCPVCGREL 445
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  793 DRGARrlEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKAT 872
Cdd:PRK03918   446 TEEHR--KELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKK 523
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  873 RKrldsELKELRQELMQVHGEKRTAEAELSRLhrevAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVA--VT 950
Cdd:PRK03918   524 AE----EYEKLKEKLIKLKGEIKSLKKELEKL----EELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEerLK 595
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  951 EANEALKKQIEELQQEARKAITEQKQKmrRLGSDLTSAQKEMKTKHKAYENavgiLSRRLQEALAAKEAADAElgqlraq 1030
Cdd:PRK03918   596 ELEPFYNEYLELKDAEKELEREEKELK--KLEEELDKAFEELAETEKRLEE----LRKELEELEKKYSEEEYE------- 662
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1031 gGSSDSSLALHERIQALEAELQAVSHSKTLLEKELQEVIAlTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKL 1110
Cdd:PRK03918   663 -ELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKE-ELEEREKAKKELEKLEKALERVEELREKVKKYKALLKER 740

                   ...
gi 1955007392 1111 ALE 1113
Cdd:PRK03918   741 ALS 743
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
397-775 4.46e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.39  E-value: 4.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  397 ESSAAETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTK---LQAQVECSHSSQQRQDSLSSEVDTL 473
Cdd:COG4717     96 ELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERleeLEERLEELRELEEELEELEAELAEL 175
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  474 KQscwDLERAMTDLQNMLEaknaslassnNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLE 553
Cdd:COG4717    176 QE---ELEELLEQLSLATE----------EELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE 242
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  554 RT--------------------------TLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQA 607
Cdd:COG4717    243 ERlkearlllliaaallallglggsllsLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELE 322
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  608 GLLEHLKLENvSLSQQLTETQHRSMKEKGRIAAQLQGIEADmLDQEAAFMQIQE----AKTMVEEDLQRRLEEFEGERER 683
Cdd:COG4717    323 ELLAALGLPP-DLSPEELLELLDRIEELQELLREAEELEEE-LQLEELEQEIAAllaeAGVEDEEELRAALEQAEEYQEL 400
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  684 LQRMADSAASLEQQL------------EQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQ--SREQSLDALQTHYDE 749
Cdd:COG4717    401 KEELEELEEQLEELLgeleellealdeEELEEELEELEEELEELEEELEELREELAELEAELEqlEEDGELAELLQELEE 480
                          410       420
                   ....*....|....*....|....*.
gi 1955007392  750 LQARLGELQGEAASREDTICLLQNEK 775
Cdd:COG4717    481 LKAELRELAEEWAALKLALELLEEAR 506
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
671-991 1.02e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.77  E-value: 1.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  671 QRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQ----------------EHLDLMKQLTLTQEALQ 734
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEyswdeidvasaereiaELEAELERLDASSDDLA 688
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  735 SREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLR 814
Cdd:COG4913    689 ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELR 768
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  815 EELaikSGQVEHLQQETAALKKQMQKIKEQFLQQkvmveaYRRDATSKDQLISELKATRKRLD----SELKELRQELMQV 890
Cdd:COG4913    769 ENL---EERIDALRARLNRAEEELERAMRAFNRE------WPAETADLDADLESLPEYLALLDrleeDGLPEYEERFKEL 839
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  891 hgEKRTAEAEL----SRLHREVAQVRQHMADLEGHLQSAQKERDemeTHLQsLQFDKEQMVAVTEANEALKKQIEELQQE 966
Cdd:COG4913    840 --LNENSIEFVadllSKLRRAIREIKERIDPLNDSLKRIPFGPG---RYLR-LEARPRPDPEVREFRQELRAVTSGASLF 913
                          330       340
                   ....*....|....*....|....*
gi 1955007392  967 ARKAITEQKQKMRRLGSDLTSAQKE 991
Cdd:COG4913    914 DEELSEARFAALKRLIERLRSEEEE 938
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
814-1338 1.11e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.38  E-value: 1.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  814 REELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRD-ATSKDQLISELKAtrkrldsELKELRQELMQVHG 892
Cdd:COG4913    287 QRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQiRGNGGDRLEQLER-------EIERLERELEERER 359
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  893 EKRTAEAELSRLH-----------REVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIE 961
Cdd:COG4913    360 RRARLEALLAALGlplpasaeefaALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIP 439
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  962 ELQQEARKAITEQkqkmrrLGSDLTSAQ-----KEMKTKHKAYENAV----GILSRRL----QEALAAKEAADAELGQLR 1028
Cdd:COG4913    440 ARLLALRDALAEA------LGLDEAELPfvgelIEVRPEEERWRGAIervlGGFALTLlvppEHYAAALRWVNRLHLRGR 513
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1029 AQGgssdsslalhERIQALEAELQAVS-HSKTLLEK---ELQEVIALTSQELEESREKVL-ELEDELQESR------GFR 1097
Cdd:COG4913    514 LVY----------ERVRTGLPDPERPRlDPDSLAGKldfKPHPFRAWLEAELGRRFDYVCvDSPEELRRHPraitraGQV 583
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1098 KKIKRLEESNKKLALELEHEkgkltgLGQSNAALREHnsiLETALAKREADLVQLNLQVQAvLQRKEEEDRQMKHLVQAL 1177
Cdd:COG4913    584 KGNGTRHEKDDRRRIRSRYV------LGFDNRAKLAA---LEAELAELEEELAEAEERLEA-LEAELDALQERREALQRL 653
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1178 QASLEKEKEkVNSLKEQVAAAKVEaghnRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAE 1257
Cdd:COG4913    654 AEYSWDEID-VASAEREIAELEAE----LERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEE 728
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1258 LAEARAQLQLLQKQLDEQLskqpvgNQEMENLKWEVDQKEREiQSLKQQLdlteqqgRKELEGLQQLLQNVKSELEMAQE 1337
Cdd:COG4913    729 LDELQDRLEAAEDLARLEL------RALLEERFAAALGDAVE-RELRENL-------EERIDALRARLNRAEEELERAMR 794

                   .
gi 1955007392 1338 D 1338
Cdd:COG4913    795 A 795
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
834-1362 1.12e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.49  E-value: 1.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  834 LKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQ 913
Cdd:TIGR04523   38 LEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKE 117
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  914 HMADLEGHLQSAQKERDEMETH----LQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKmrrlgsdltsaQ 989
Cdd:TIGR04523  118 QKNKLEVELNKLEKQKKENKKNidkfLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNI-----------Q 186
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  990 KEMKTKHKAYenavgilsRRLQEALAAKEAADAELGQLRAQggssdsslalherIQALEAELQAVSHSKTLLEKELQEVi 1069
Cdd:TIGR04523  187 KNIDKIKNKL--------LKLELLLSNLKKKIQKNKSLESQ-------------ISELKKQNNQLKDNIEKKQQEINEK- 244
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1070 altSQELEESREKVLELEDELQE-SRGFRKKIKRLEESNKKLAlelehekgkltglgQSNAALREHNSILETALAKREAD 1148
Cdd:TIGR04523  245 ---TTEISNTQTQLNQLKDEQNKiKKQLSEKQKELEQNNKKIK--------------ELEKQLNQLKSEISDLNNQKEQD 307
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1149 LvqlNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEH 1228
Cdd:TIGR04523  308 W---NKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQ 384
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1229 LVQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLD 1308
Cdd:TIGR04523  385 EIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRE 464
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1955007392 1309 LTEQQgrkeLEGLQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELKNNMKT 1362
Cdd:TIGR04523  465 SLETQ----LKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKD 514
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
560-1107 1.14e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.38  E-value: 1.14e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  560 KLKASQAEISSLQSVRQWY--QQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSQQLTETQHRsmkEKGR 637
Cdd:COG4913    266 AARERLAELEYLRAALRLWfaQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGD---RLEQ 342
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  638 IAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQvklTLLQRDQQLEALQQ 717
Cdd:COG4913    343 LEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEE---ALAEAEAALRDLRR 419
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  718 EHLDLMKQLtltqEALQSREQSLDAlqtHYDELQARLGELQGEAASREDTIC-LLQ----NEK----------------I 776
Cdd:COG4913    420 ELRELEAEI----ASLERRKSNIPA---RLLALRDALAEALGLDEAELPFVGeLIEvrpeEERwrgaiervlggfaltlL 492
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  777 ILEAALQAAKS------GKEELD-RGARRLEEGTEETSETLEKLREELAIKSGQ--------------------VEHLQQ 829
Cdd:COG4913    493 VPPEHYAAALRwvnrlhLRGRLVyERVRTGLPDPERPRLDPDSLAGKLDFKPHPfrawleaelgrrfdyvcvdsPEELRR 572
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  830 ETAALKKQMQkIKeqflQQKVMVEAYRRDATSKDQLI-SELKATRKRLDSELKELRQELmqvhgekRTAEAELSRLHREV 908
Cdd:COG4913    573 HPRAITRAGQ-VK----GNGTRHEKDDRRRIRSRYVLgFDNRAKLAALEAELAELEEEL-------AEAEERLEALEAEL 640
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  909 AQVRQHMADLEGHLQSAQKERD--EMETHLQSLQfdkEQMVAVTEAN---EALKKQIEELQQE---ARKAITEQKQKMRR 980
Cdd:COG4913    641 DALQERREALQRLAEYSWDEIDvaSAEREIAELE---AELERLDASSddlAALEEQLEELEAEleeLEEELDELKGEIGR 717
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  981 LGSDLTSAQKEMKTKHKAYENAVGIlsrrlqEALAAKEAADAELGQLRAQGGSSDSSLALHERIQALEAElqavshsktl 1060
Cdd:COG4913    718 LEKELEQAEEELDELQDRLEAAEDL------ARLELRALLEERFAAALGDAVERELRENLEERIDALRAR---------- 781
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1955007392 1061 LEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESN 1107
Cdd:COG4913    782 LNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDG 828
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
365-963 1.32e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 53.30  E-value: 1.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  365 LQAAAAEHQDQGQEVNGEVRSRRDSICSSVSlESSAAETQEemLQVLKEKM-RLEGQLEALSLEASQALKEKAE------ 437
Cdd:pfam12128  270 DETLIASRQEERQETSAELNQLLRTLDDQWK-EKRDELNGE--LSAADAAVaKDRSELEALEDQHGAFLDADIEtaaadq 346
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  438 -----LQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVDtlKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQY 512
Cdd:pfam12128  347 eqlpsWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK--EQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESEL 424
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  513 ------QRLMAKVEDMQ--------RSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISSLQSVRQWY 578
Cdd:pfam12128  425 reqleaGKLEFNEEEYRlksrlgelKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQA 504
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  579 QQQLALAQEARVRLQGEMAHIQVGQMTQAG-LLEHLKLENVSLSQQL-----TETQHRSMKEKGRIAAQLQG---IEADM 649
Cdd:pfam12128  505 SEALRQASRRLEERQSALDELELQLFPQAGtLLHFLRKEAPDWEQSIgkvisPELLHRTDLDPEVWDGSVGGelnLYGVK 584
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  650 LDQEAafMQIQEAKTMvEEDLQRRLEEFEgerERLQRMADSAASLEQQLEQVKLTLLQRDQQLE----ALQQEHLDLM-- 723
Cdd:pfam12128  585 LDLKR--IDVPEWAAS-EEELRERLDKAE---EALQSAREKQAAAEEQLVQANGELEKASREETfartALKNARLDLRrl 658
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  724 ------------KQLTLTQEALQSREQSLDALQTHYD-ELQARLGELQGEaaSREDTICLLQNEKII---LEAALQAAKS 787
Cdd:pfam12128  659 fdekqsekdkknKALAERKDSANERLNSLEAQLKQLDkKHQAWLEEQKEQ--KREARTEKQAYWQVVegaLDAQLALLKA 736
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  788 GKEELDRGARRLEEGTEETSETLEKLR----EELAIKSGQVEHLQQETAALKKQMQKIKE--QFLQQKVMVEAYRRDATS 861
Cdd:pfam12128  737 AIAARRSGAKAELKALETWYKRDLASLgvdpDVIAKLKREIRTLERKIERIAVRRQEVLRyfDWYQETWLQRRPRLATQL 816
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  862 KD--QLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSL 939
Cdd:pfam12128  817 SNieRAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGERLAQLE 896
                          650       660
                   ....*....|....*....|....
gi 1955007392  940 QFDKEQMVAVteanEALKKQIEEL 963
Cdd:pfam12128  897 DLKLKRDYLS----ESVKKYVEHF 916
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
400-1030 1.62e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 53.05  E-value: 1.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  400 AAETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALStKLQAQVEcshsSQQRQDSLSSEVDTLKQSCWD 479
Cdd:TIGR00618  234 ALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLE-ETQERIN----RARKAAPLAAHIKAVTQIEQQ 308
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  480 LERAMTDLQNM------LEAKNASLASSNNDLQVAEEQYQRLMAKvEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLE 553
Cdd:TIGR00618  309 AQRIHTELQSKmrsrakLLMKRAAHVKQQSSIEEQRRLLQTLHSQ-EIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ 387
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  554 RTTLTSKLKASQAEISSLQSVRqwyQQQLALAQEARVrLQGEMAHIQVGQMTQAGLLEHLKL--ENVSLSQQLTETQHRS 631
Cdd:TIGR00618  388 KTTLTQKLQSLCKELDILQREQ---ATIDTRTSAFRD-LQGQLAHAKKQQELQQRYAELCAAaiTCTAQCEKLEKIHLQE 463
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  632 MKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQ 711
Cdd:TIGR00618  464 SAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETS 543
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  712 LEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEE 791
Cdd:TIGR00618  544 EEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQP 623
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  792 ldrgARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETaaLKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKA 871
Cdd:TIGR00618  624 ----EQDLQDVRLHLQQCSQELALKLTALHALQLTLTQER--VREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKE 697
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  872 TRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQvrqhmaDLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTE 951
Cdd:TIGR00618  698 MLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAA------REDALNQSLKELMHQARTVLKARTEAHFNNNEEVT 771
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1955007392  952 ANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQ 1030
Cdd:TIGR00618  772 AALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQ 850
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
863-1010 2.19e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 50.69  E-value: 2.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  863 DQLISELKATRKRLDSELKELRQE-------LMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERD----- 930
Cdd:COG1579     16 DSELDRLEHRLKELPAELAELEDElaalearLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyealq 95
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  931 -EMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRR 1009
Cdd:COG1579     96 kEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPE 175

                   .
gi 1955007392 1010 L 1010
Cdd:COG1579    176 L 176
PTZ00121 PTZ00121
MAEBL; Provisional
852-1426 2.55e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 2.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  852 VEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTA-EAELSRLHREVAQVRQHMADLEGHLQSAQKERD 930
Cdd:PTZ00121  1226 AEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAiKAEEARKADELKKAEEKKKADEAKKAEEKKKAD 1305
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  931 EMETHLQSLQFDKEQMVAVTEAN---EALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILS 1007
Cdd:PTZ00121  1306 EAKKKAEEAKKADEAKKKAEEAKkkaDAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKK 1385
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1008 RRLQEALAAKEAADAELGQLRAQggssDSSLALHERIQALEAELQA--VSHSKTLLEKELQEVIALTSQELEESREKVLE 1085
Cdd:PTZ00121  1386 KAEEKKKADEAKKKAEEDKKKAD----ELKKAAAAKKKADEAKKKAeeKKKADEAKKKAEEAKKADEAKKKAEEAKKAEE 1461
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1086 LEDELQESRGFRKKIKRLEESNKKLALELEHEKGKltglgqsnaalREHNSILETALAKREAD-LVQLNLQVQAVLQRKE 1164
Cdd:PTZ00121  1462 AKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAK-----------KKADEAKKAAEAKKKADeAKKAEEAKKADEAKKA 1530
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1165 EEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQ-AKEHLVQKLQAEADDLQIR 1243
Cdd:PTZ00121  1531 EEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEeARIEEVMKLYEEEKKMKAE 1610
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1244 EGKHSQE----IAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENL--KWEVDQKEREIQSLKQQLDLTEQQGRKE 1317
Cdd:PTZ00121  1611 EAKKAEEakikAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKikAAEEAKKAEEDKKKAEEAKKAEEDEKKA 1690
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1318 LEGLQQLLQNVKSELEMAQEDLSMTQKDKfmlQAKVSELKNNMKTLLQQNQQLKLDLRRGAAKTRKEPKGEASSSNPATP 1397
Cdd:PTZ00121  1691 AEALKKEAEEAKKAEELKKKEAEEKKKAE---ELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEE 1767
                          570       580
                   ....*....|....*....|....*....
gi 1955007392 1398 IKipdcpvpaslLEELLRPPPAVSKEPLK 1426
Cdd:PTZ00121  1768 KK----------AEEIRKEKEAVIEEELD 1786
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1036-1263 2.74e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 2.74e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1036 SSLALHERIQALEAELQAVSHSKTLLEKELQEV---IALTSQELEESREKVLELEDELQESRG----FRKKIKRLEESNK 1108
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALkkeEKALLKQLAALERRIAALARRIRALEQelaaLEAELAELEKEIA 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1109 KLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKV 1188
Cdd:COG4942     94 ELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1955007392 1189 NSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQiregkhsQEIAQFQAELAEARA 1263
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE-------ALIARLEAEAAAAAE 241
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
554-970 3.76e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 3.76e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  554 RTTLTSKLKASQAEISSLQ-SVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKlenvSLSQQLTETQHRSM 632
Cdd:COG4717     44 RAMLLERLEKEADELFKPQgRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELE----ELEAELEELREELE 119
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  633 KekgriAAQLQGIEADMLDQEAAFMQIQEAKTMVEEdLQRRLEEFEGERERLQRMADSAASLEQQLEQ--------VKLT 704
Cdd:COG4717    120 K-----LEKLLQLLPLYQELEALEAELAELPERLEE-LEERLEELRELEEELEELEAELAELQEELEElleqlslaTEEE 193
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  705 LLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQ---------------ARLGELQGEAASREDTIC 769
Cdd:COG4717    194 LQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAAleerlkearlllliaAALLALLGLGGSLLSLIL 273
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  770 ------------------LLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQET 831
Cdd:COG4717    274 tiagvlflvlgllallflLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELL 353
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  832 AALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKR--LDSELKELRQELMQVHGEKRT--AEAELSRLHRE 907
Cdd:COG4717    354 REAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYqeLKEELEELEEQLEELLGELEEllEALDEEELEEE 433
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1955007392  908 VAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEAnEALKKQIEELQQEARKA 970
Cdd:COG4717    434 LEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQEL-EELKAELRELAEEWAAL 495
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
598-758 5.70e-06

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 50.05  E-value: 5.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  598 HIQVGQMTQAG-LLehLKLENVSLSQQLTETQHRsmkekgriAAQLQGIEADMLDQEAAFMQIQEAKTMVEEdLQRRLEE 676
Cdd:COG1566     60 LVKEGDRVKKGqVL--ARLDPTDLQAALAQAEAQ--------LAAAEAQLARLEAELGAEAEIAAAEAQLAA-AQAQLDL 128
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  677 FEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEhLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGE 756
Cdd:COG1566    129 AQRELERYQALYKKGAVSQQELDEARAALDAAQAQLEAAQAQ-LAQAQAGLREEEELAAAQAQVAQAEAALAQAELNLAR 207

                   ..
gi 1955007392  757 LQ 758
Cdd:COG1566    208 TT 209
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
391-607 6.16e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 6.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  391 CSSVSLESSAAETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDSLSSEV 470
Cdd:COG4942     13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  471 DTLKQscwDLERAMTDLQNMLEA--------------KNASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDL 536
Cdd:COG4942     93 AELRA---ELEAQKEELAELLRAlyrlgrqpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1955007392  537 RQQMTALQSQLQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQA 607
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
542-787 6.38e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 6.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  542 ALQSQLQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLS 621
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  622 QQLTETQHRsmkekgrIAAQLQGIEADMLDQEAAFMQIQEAKtmveEDLQRRLEEFEGERERLQRMADSAASLEQQLEQV 701
Cdd:COG4942     97 AELEAQKEE-------LAELLRALYRLGRQPPLALLLSPEDF----LDAVRRLQYLKYLAPARREQAEELRADLAELAAL 165
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  702 KLTLLQRDQQLEALQQEHLDLMKQLtltQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTIcllqnEKIILEAA 781
Cdd:COG4942    166 RAELEAERAELEALLAELEEERAAL---EALKAERQKLLARLEKELAELAAELAELQQEAEELEALI-----ARLEAEAA 237

                   ....*.
gi 1955007392  782 LQAAKS 787
Cdd:COG4942    238 AAAERT 243
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
378-980 8.37e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 8.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  378 EVNGEVRSRRDSICSSVSLESSAAETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAqLAALSTKLQAQVEcsh 457
Cdd:PRK03918   173 EIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE-LKEEIEELEKELE--- 248
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  458 ssqqrqdSLSSEVDTLKQSCWDLERAMTDLQ---NMLEAKNASLassnNDLQVAEEQYQRL---MAKVEDMQRSMLSKDN 531
Cdd:PRK03918   249 -------SLEGSKRKLEEKIRELEERIEELKkeiEELEEKVKEL----KELKEKAEEYIKLsefYEEYLDELREIEKRLS 317
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  532 TVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARvRLQGEMAHIQVgqmtqagllE 611
Cdd:PRK03918   318 RLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELE-RLKKRLTGLTP---------E 387
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  612 HLKLENVSLSQQLTETQHRSMKEKGRIaAQLQGIEADMldqEAAFMQIQEAKT--------MVEEDLQRRLEEFEGERER 683
Cdd:PRK03918   388 KLEKELEELEKAKEEIEEEISKITARI-GELKKEIKEL---KKAIEELKKAKGkcpvcgreLTEEHRKELLEEYTAELKR 463
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  684 LQRMADSAASLEQQLEQVKL---TLLQRDQQLEALQQehldLMKQLTLTQEALQSRE-QSLDALQTHYDELQARLGELQG 759
Cdd:PRK03918   464 IEKELKEIEEKERKLRKELReleKVLKKESELIKLKE----LAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKG 539
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  760 EAASREDTI---CLLQNEKIILEAALQAAKSGKEELdrgarrleegteetsetlEKLREELAIKSgqVEHLQQETaalkK 836
Cdd:PRK03918   540 EIKSLKKELeklEELKKKLAELEKKLDELEEELAEL------------------LKELEELGFES--VEELEERL----K 595
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  837 QMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRL---DSELKELRQELMQVhgEKRTAEAELSRLHREVAQVRQ 913
Cdd:PRK03918   596 ELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELaetEKRLEELRKELEEL--EKKYSEEEYEELREEYLELSR 673
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1955007392  914 HMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELqQEARKAITEQKQKMRR 980
Cdd:PRK03918   674 ELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERV-EELREKVKKYKALLKE 739
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1138-1449 9.84e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.44  E-value: 9.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1138 LETALAKREADLVQLNLQVQAVLQRKE--EEDRQMKHLVQALQaslekekekVNSLKEQVAAAKVEAGHNRRHFKAASLE 1215
Cdd:TIGR02168  191 LEDILNELERQLKSLERQAEKAERYKElkAELRELELALLVLR---------LEELREELEELQEELKEAEEELEELTAE 261
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1216 LSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELA---EARAQLQLLQKQLDEQLSKQPvgnQEMENLKWE 1292
Cdd:TIGR02168  262 LQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQilrERLANLERQLEELEAQLEELE---SKLDELAEE 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1293 VDQKEREIQSLKQQLDLTEQQG---RKELEGLQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELKNNmKTLLQQNQQ 1369
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELeelEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEAR-LERLEDRRE 417
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1370 LKLDLRRGAAKTRKEPKGEASSSNPATPIKIPD----CPVPASLLEELLRPPPAVSKEPLKNLNSCLQQLKQEMDSLQRQ 1445
Cdd:TIGR02168  418 RLQQEIEELLKKLEEAELKELQAELEELEEELEelqeELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERL 497

                   ....
gi 1955007392 1446 MEEH 1449
Cdd:TIGR02168  498 QENL 501
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
710-1132 1.01e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 1.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  710 QQLEALQQEhldlMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDticllqneKIILEAALQAAKSGK 789
Cdd:COG4717     71 KELKELEEE----LKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEK--------LLQLLPLYQELEALE 138
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  790 EELDRGARRLEEGTEETSETLEkLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVM-VEAYRRDATSKDQLISE 868
Cdd:COG4717    139 AELAELPERLEELEERLEELRE-LEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEeLEELQQRLAELEEELEE 217
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  869 LKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLhreVAQVRQHMADLEGHLQSAQKERDEMET------HLQSLQFD 942
Cdd:COG4717    218 AQEELEELEEELEQLENELEAAALEERLKEARLLLL---IAAALLALLGLGGSLLSLILTIAGVLFlvlgllALLFLLLA 294
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  943 KEQMVAVTEANEA-LKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAAd 1021
Cdd:COG4717    295 REKASLGKEAEELqALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA- 373
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1022 aelgQLRAQGGSSD-----SSLALHERIQALEAELQAVSHSKTLLEKELQEVIALTS-----QELEESREKVLELEDEL- 1090
Cdd:COG4717    374 ----ALLAEAGVEDeeelrAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDeeeleEELEELEEELEELEEELe 449
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 1955007392 1091 ---QESRGFRKKIKRLEESNK--KLALELEHEKGKLTGLGQSNAALR 1132
Cdd:COG4717    450 elrEELAELEAELEQLEEDGElaELLQELEELKAELRELAEEWAALK 496
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
667-1330 1.07e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.22  E-value: 1.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  667 EEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQrDQQLEALQQEHLDLmkqltlTQEALQSREQSLDA-LQT 745
Cdd:pfam12128  229 DIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKS-DETLIASRQEERQE------TSAELNQLLRTLDDqWKE 301
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  746 HYDELQARLGELQGEAASREDTICLLQNE-KIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKL----REELAIK 820
Cdd:pfam12128  302 KRDELNGELSAADAAVAKDRSELEALEDQhGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHqdvtAKYNRRR 381
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  821 SGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSK-----DQLISELKATRKRLDSELKELRQELMQVHGE-- 893
Cdd:pfam12128  382 SKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESElreqlEAGKLEFNEEEYRLKSRLGELKLRLNQATATpe 461
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  894 ----KRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSL-QFDKEQMVAVTEANEALKKQIEELQQEAR 968
Cdd:pfam12128  462 lllqLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQAsRRLEERQSALDELELQLFPQAGTLLHFLR 541
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  969 KAITEQKQKMRRLGSDL----TSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAElgQLRAQGGSSDSSL-ALHER 1043
Cdd:pfam12128  542 KEAPDWEQSIGKVISPEllhrTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEE--ELRERLDKAEEALqSAREK 619
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1044 IQALEAELQAVShsKTLLEKELQEVIALTSqeLEESREKVLELEDELQ-ESRGFRKKIKRLEESNKKLALELEHEKgKLT 1122
Cdd:pfam12128  620 QAAAEEQLVQAN--GELEKASREETFARTA--LKNARLDLRRLFDEKQsEKDKKNKALAERKDSANERLNSLEAQL-KQL 694
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1123 GLGQSNAALREHNSILETALAKREADLV-------QLNLQVQAVLQRKEEEDRQMKHLVQALQASLEK---EKEKVNSLK 1192
Cdd:pfam12128  695 DKKHQAWLEEQKEQKREARTEKQAYWQVvegaldaQLALLKAAIAARRSGAKAELKALETWYKRDLASlgvDPDVIAKLK 774
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1193 EQVAA--AKVEAGHNRRHfKAASLELSEVKKELQAKEHL---VQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQLQL 1267
Cdd:pfam12128  775 REIRTleRKIERIAVRRQ-EVLRYFDWYQETWLQRRPRLatqLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEK 853
                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1955007392 1268 LQKQLDEQLSKQPVGNQEMENLK--WEVDQKEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVKS 1330
Cdd:pfam12128  854 QQVRLSENLRGLRCEMSKLATLKedANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHFKN 918
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
616-958 2.13e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 49.35  E-value: 2.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  616 ENVSLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEaafmqiqeaKTMVEEDLQRRLEEFEGERERLQRMADSAASLE 695
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQE---------KEEKAREVERRRKLEEAEKARQAEMDRQAAIYA 337
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  696 QQleqvKLTLLQRDQQLEALQQE----HLDLMKQLTLTQEALQSREqsLDALQTHYDELQARLgeLQGEAASREDTICLL 771
Cdd:pfam17380  338 EQ----ERMAMERERELERIRQEerkrELERIRQEEIAMEISRMRE--LERLQMERQQKNERV--RQELEAARKVKILEE 409
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  772 QNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALK-KQMQKIKEQflQQKV 850
Cdd:pfam17380  410 ERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKrKKLELEKEK--RDRK 487
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  851 MVEAYRRDATSKD-----QLISELKATRKRLDSELKElRQELMQVHGEKRTAEAElSRLHREVAQVRQhmadleghLQSA 925
Cdd:pfam17380  488 RAEEQRRKILEKEleerkQAMIEEERKRKLLEKEMEE-RQKAIYEEERRREAEEE-RRKQQEMEERRR--------IQEQ 557
                          330       340       350
                   ....*....|....*....|....*....|...
gi 1955007392  926 QKERDEMETHLQSLQFDKEQMVAVTEANEALKK 958
Cdd:pfam17380  558 MRKATEERSRLEAMEREREMMRQIVESEKARAE 590
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
486-993 2.28e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 48.95  E-value: 2.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  486 DLQNMLEAKNaSLASSNndLQVAEEQYQRLMAKVED----MQRSMLSKDNTVHDLR-------QQMTALQSQLQQVQLER 554
Cdd:pfam05483  268 DKANQLEEKT-KLQDEN--LKELIEKKDHLTKELEDikmsLQRSMSTQKALEEDLQiatkticQLTEEKEAQMEELNKAK 344
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  555 TTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAH--IQVGQMTQAGLLEHLKLENVSLSQQLTETQHRSM 632
Cdd:pfam05483  345 AAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKksSELEEMTKFKNNKEVELEELKKILAEDEKLLDEK 424
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  633 KEKGRIAAQLQGIEADML------DQEAAFMQIQ-EAKTMVEEDLQRRLEEF--EGERERLQRMADSAASLEQQLEQVKL 703
Cdd:pfam05483  425 KQFEKIAEELKGKEQELIfllqarEKEIHDLEIQlTAIKTSEEHYLKEVEDLktELEKEKLKNIELTAHCDKLLLENKEL 504
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  704 TllqrdqqlealqQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEkiiLEAALQ 783
Cdd:pfam05483  505 T------------QEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDE---VKCKLD 569
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  784 AAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKD 863
Cdd:pfam05483  570 KSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAK 649
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  864 QLISELKATRKRlDSELKELRQELMQVHGEKRTAEA-ELSRLHREVAQVRQH-----MADLEGHLQSAQKERDEMETHLq 937
Cdd:pfam05483  650 QKFEEIIDNYQK-EIEDKKISEEKLLEEVEKAKAIAdEAVKLQKEIDKRCQHkiaemVALMEKHKHQYDKIIEERDSEL- 727
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1955007392  938 SLQFDKEQmvAVTEANEALKKQIEELQQE---ARKAIT---EQKQKMRRLGSDLTSAQKEMK 993
Cdd:pfam05483  728 GLYKNKEQ--EQSSAKAALEIELSNIKAEllsLKKQLEiekEEKEKLKMEAKENTAILKDKK 787
PRK12704 PRK12704
phosphodiesterase; Provisional
839-992 2.49e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 48.62  E-value: 2.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  839 QKIKEQFLQQKVMVEAYRRDA-TSKDQLISELKatrkrldSELKELRQELmqvHGEKRTAEAELSRLHRevaQVRQHMAD 917
Cdd:PRK12704    31 AKIKEAEEEAKRILEEAKKEAeAIKKEALLEAK-------EEIHKLRNEF---EKELRERRNELQKLEK---RLLQKEEN 97
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1955007392  918 LEGHLQSAQKERDEMETHLQSLqfdkeqmvavteanEALKKQIEELQQEARKAITEQKQKMRRLgSDLTSAQ-KEM 992
Cdd:PRK12704    98 LDRKLELLEKREEELEKKEKEL--------------EQKQQELEKKEEELEELIEEQLQELERI-SGLTAEEaKEI 158
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
668-1178 2.70e-05

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 49.05  E-value: 2.70e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  668 EDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHY 747
Cdd:pfam10174  268 EDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTEV 347
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  748 DELQARLGELQGEAASREDTICLLQNEKIILEAALQAAksgKEELDRGARRLEEGTEETSETLEKLRE---ELAIKSGQV 824
Cdd:pfam10174  348 DALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDL---KDMLDVKERKINVLQKKIENLQEQLRDkdkQLAGLKERV 424
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  825 EHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRldsELKELRQELMQVHGEKRTAEAELSRL 904
Cdd:pfam10174  425 KSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKK---ENKDLKEKVSALQPELTEKESSLIDL 501
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  905 HREVAQVRQHMADLEGHLQS---AQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEA---RKAITEQKQKM 978
Cdd:pfam10174  502 KEHASSLASSGLKKDSKLKSleiAVEQKKEECSKLENQLKKAHNAEEAVRTNPEINDRIRLLEQEVaryKEESGKAQAEV 581
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  979 RRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQGGSSDSslalheriQALEAELQAVSHSK 1058
Cdd:pfam10174  582 ERLLGILREVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLE--------EARRREDNLADNSQ 653
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1059 TLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKrlEESNKKLALELEHEKGKLTglgqsnAALREHNS-- 1136
Cdd:pfam10174  654 QLQLEELMGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLR--AERRKQLEEILEMKQEALL------AAISEKDAni 725
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 1955007392 1137 -ILETALAKREADlvqlnlqVQAVLQRKEEEDRQMKHLVQALQ 1178
Cdd:pfam10174  726 aLLELSSSKKKKT-------QEEVMALKREKDRLVHQLKQQTQ 761
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1072-1357 2.74e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 2.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1072 TSQELEESREKVLELEDELQEsrgFRKKIKRLE------ESNKKLALELEHEKGKLTGLG--QSNAALREHNSILETALA 1143
Cdd:COG1196    177 AERKLEATEENLERLEDILGE---LERQLEPLErqaekaERYRELKEELKELEAELLLLKlrELEAELEELEAELEELEA 253
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1144 KREADLVQLNlQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKEL 1223
Cdd:COG1196    254 ELEELEAELA-ELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEEL 332
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1224 QAKEHLVQKLQAEADDLQIREgkhsQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSL 1303
Cdd:COG1196    333 EELEEELEELEEELEEAEEEL----EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1955007392 1304 KQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELK 1357
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
823-1009 2.95e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 2.95e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  823 QVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELS 902
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  903 RLHREVAQV--------RQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQM---VAVTEANEALKKQIEELQQEARKAI 971
Cdd:COG4942    101 AQKEELAELlralyrlgRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAeelRADLAELAALRAELEAERAELEALL 180
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1955007392  972 TEQKQKMRRLGSDLTSAQK---EMKTKHKAYENAVGILSRR 1009
Cdd:COG4942    181 AELEEERAALEALKAERQKllaRLEKELAELAAELAELQQE 221
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
620-931 3.46e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 3.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  620 LSQQLTETQhRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAkTMVEED---LQRRLEEFEGERERLQRMADSAASLEQ 696
Cdd:COG4913    615 LEAELAELE-EELAEAEERLEALEAELDALQERREALQRLAEY-SWDEIDvasAEREIAELEAELERLDASSDDLAALEE 692
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  697 QLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDAL-----QTHYDELQARLGELQGEAASREdticLL 771
Cdd:COG4913    693 QLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAedlarLELRALLEERFAAALGDAVERE----LR 768
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  772 QNekiiLEAALQAAKSGKEELDRGARRL--------EEGTEETSETLEKLREELAI-----KSGQVEHLQQETAALKKQM 838
Cdd:COG4913    769 EN----LEERIDALRARLNRAEEELERAmrafnrewPAETADLDADLESLPEYLALldrleEDGLPEYEERFKELLNENS 844
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  839 QKIKEQFLQQkvmVEAYRRDATSK-DQLISELKAT------------RKRLDSELKELRQELMQVHGEKRTAEAELSRLH 905
Cdd:COG4913    845 IEFVADLLSK---LRRAIREIKERiDPLNDSLKRIpfgpgrylrleaRPRPDPEVREFRQELRAVTSGASLFDEELSEAR 921
                          330       340
                   ....*....|....*....|....*..
gi 1955007392  906 REvaQVRQHMADLEG-HLQSAQKERDE 931
Cdd:COG4913    922 FA--ALKRLIERLRSeEEESDRRWRAR 946
PTZ00121 PTZ00121
MAEBL; Provisional
611-1201 4.77e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.21  E-value: 4.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  611 EHLKLENVSLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEG---ERERLQRM 687
Cdd:PTZ00121  1241 EAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKkaeEAKKADEA 1320
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  688 ADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDT 767
Cdd:PTZ00121  1321 KKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKA 1400
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  768 ICLLQNEKIILEAAlqAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKsgQVEHLQQETAALKKQMQKIKEQFLQ 847
Cdd:PTZ00121  1401 EEDKKKADELKKAA--AAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKK--KAEEAKKAEEAKKKAEEAKKADEAK 1476
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  848 QKVMvEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHgEKRTAE----AELSRLHREVAQVRQHMADLEGHLQ 923
Cdd:PTZ00121  1477 KKAE-EAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAE-EAKKADeakkAEEAKKADEAKKAEEKKKADELKKA 1554
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  924 SAQKERDEMETHLQSLQFDKEQMVAVTEANEAlkKQIEELQQEARKAITEQKQKMR----------RLGSDLTSAQKEMK 993
Cdd:PTZ00121  1555 EELKKAEEKKKAEEAKKAEEDKNMALRKAEEA--KKAEEARIEEVMKLYEEEKKMKaeeakkaeeaKIKAEELKKAEEEK 1632
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  994 TKHKAYENAVGILSRRLQEALAAKEAADAELGQLrAQGGSSDSSLAlhERIQALEAELQAVSHSKTLLEKELQEVIALTS 1073
Cdd:PTZ00121  1633 KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE-AKKAEEDKKKA--EEAKKAEEDEKKAAEALKKEAEEAKKAEELKK 1709
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1074 QELEESReKVLELEDELQESRGFRKKIKRLEESNKKLALEL---EHEKGKLTGLGQSNAALREHNSILETALAKREADlv 1150
Cdd:PTZ00121  1710 KEAEEKK-KAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAkkdEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD-- 1786
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1955007392 1151 qlnlqvQAVLQRKEEEDRQMKHLVQALQASLEKEKEK---VNSLKEQVAAAKVE 1201
Cdd:PTZ00121  1787 ------EEDEKRRMEVDKKIKDIFDNFANIIEGGKEGnlvINDSKEMEDSAIKE 1834
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
508-1256 4.78e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.19  E-value: 4.78e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  508 AEEQYQRLMA----KVEDMQRSmLSKDNTVHD-----LRQQMTALQSQLQQVQLERTTLtsklkasqAEISSLQSVRQwy 578
Cdd:pfam15921   72 GKEHIERVLEeyshQVKDLQRR-LNESNELHEkqkfyLRQSVIDLQTKLQEMQMERDAM--------ADIRRRESQSQ-- 140
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  579 qqqlalaQEARVRLQGEMAHIQVGQMTQAGLLEhlklenvSLSQQLTETQHRSMKEKGriaaQLQGIEADMLD-QEAAFM 657
Cdd:pfam15921  141 -------EDLRNQLQNTVHELEAAKCLKEDMLE-------DSNTQIEQLRKMMLSHEG----VLQEIRSILVDfEEASGK 202
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  658 QIQEAKTM-------VEEDLQRRLEEFEGErerLQRMADSAASLEQQLEQVKltlLQRDQQLEALQQEHLDLMKQLT--- 727
Cdd:pfam15921  203 KIYEHDSMstmhfrsLGSAISKILRELDTE---ISYLKGRIFPVEDQLEALK---SESQNKIELLLQQHQDRIEQLIseh 276
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  728 ------LTQEALQSREQS------LDALQT-----------HYDELQARLGELQGE--AASR--EDTICLLQNEKIILEA 780
Cdd:pfam15921  277 eveitgLTEKASSARSQAnsiqsqLEIIQEqarnqnsmymrQLSDLESTVSQLRSElrEAKRmyEDKIEELEKQLVLANS 356
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  781 ALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQ--------------VEHLQQE-----------TAALK 835
Cdd:pfam15921  357 ELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitIDHLRRElddrnmevqrlEALLK 436
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  836 KQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRT-----------------AE 898
Cdd:pfam15921  437 AMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTvsdltaslqekeraieaTN 516
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  899 AELSRLHREV---AQVRQHMADLEGHLQSAQKERDEMethlqslqfdKEQMVAVTEANEALKKQIEELQ----QEARKAI 971
Cdd:pfam15921  517 AEITKLRSRVdlkLQELQHLKNEGDHLRNVQTECEAL----------KLQMAEKDKVIEILRQQIENMTqlvgQHGRTAG 586
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  972 TEQKQKmrrlgsdltsAQKEMKtkhkayenavgILSRRLQEALAAKEAADAELGQLRAQGGSSDSSLALHERIQALEAEL 1051
Cdd:pfam15921  587 AMQVEK----------AQLEKE-----------INDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERL 645
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1052 QAVSHSKTLLEKELQEVialtsqelEESREKVLELEDELQE-SRGFRKKIKRLEESNKKLAL-------ELEHEKGKLTG 1123
Cdd:pfam15921  646 RAVKDIKQERDQLLNEV--------KTSRNELNSLSEDYEVlKRNFRNKSEEMETTTNKLKMqlksaqsELEQTRNTLKS 717
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1124 L-GQSNAALREHNSILETALAKR-EADLVQLNLQvqaVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAA--AK 1199
Cdd:pfam15921  718 MeGSDGHAMKVAMGMQKQITAKRgQIDALQSKIQ---FLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGelEV 794
                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1955007392 1200 VEAGHNRRHFKAASLELSEVKKELQAKE--HLVQKLQAEADDLQIregKHSQEIAQFQA 1256
Cdd:pfam15921  795 LRSQERRLKEKVANMEVALDKASLQFAEcqDIIQRQEQESVRLKL---QHTLDVKELQG 850
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
853-1030 7.82e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 7.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  853 EAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEM 932
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  933 ETHLQSL-----------QFDKEQMV----AVTEANEALKKQIEELQQEA------RKAITEQKQKMRRLGSDLTSAQKE 991
Cdd:COG4942    110 LRALYRLgrqpplalllsPEDFLDAVrrlqYLKYLAPARREQAEELRADLaelaalRAELEAERAELEALLAELEEERAA 189
                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1955007392  992 MKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQ 1030
Cdd:COG4942    190 LEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
675-1118 8.29e-05

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 46.98  E-value: 8.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  675 EEFEGERERLQRMADSAA---SLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQ 751
Cdd:pfam19220    3 QRNELLRVRLGEMADRLEdlrSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAE 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  752 ARLGELQGEAASredticllqnekiiLEAALQAAKSGKEELdrgarrleegteetsetleklREELAIKSGQVEHLQQET 831
Cdd:pfam19220   83 GELEELVARLAK--------------LEAALREAEAAKEEL---------------------RIELRDKTAQAEALERQL 127
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  832 AALKKQMQKIKEQflqqkvmVEAYRRDATSKDQLISelkatrkRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQV 911
Cdd:pfam19220  128 AAETEQNRALEEE-------NKALREEAQAAEKALQ-------RAEGELATARERLALLEQENRRLQALSEEQAAELAEL 193
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  912 RQHMADLEGHLQSAQKERDEMETHLqslqfdkeqmVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQK- 990
Cdd:pfam19220  194 TRRLAELETQLDATRARLRALEGQL----------AAEQAERERAEAQLEEAVEAHRAERASLRMKLEALTARAAATEQl 263
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  991 --EMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQggssdsslalHERIQALEAELQAVSHSKTLLEKELQEV 1068
Cdd:pfam19220  264 laEARNQLRDRDEAIRAAERRLKEASIERDTLERRLAGLEAD----------LERRTQQFQEMQRARAELEERAEMLTKA 333
                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1955007392 1069 IALTSQELEESREKVLELEDELQE-SRGFRKKIKRLEESNKKLALELEHEK 1118
Cdd:pfam19220  334 LAAKDAALERAEERIASLSDRIAElTKRFEVERAALEQANRRLKEELQRER 384
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
740-902 9.14e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.69  E-value: 9.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  740 LDALQTHYDELQARLGELQGEAASredticlLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREEL-- 817
Cdd:COG1579     12 LQELDSELDRLEHRLKELPAELAE-------LEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLgn 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  818 AIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKAT----RKRLDSELKELRQELMQVHGE 893
Cdd:COG1579     85 VRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAEleekKAELDEELAELEAELEELEAE 164

                   ....*....
gi 1955007392  894 KRTAEAELS 902
Cdd:COG1579    165 REELAAKIP 173
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
897-1133 9.30e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 9.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  897 AEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQfdkEQMVAVTEANEALKKQIEELQQEARKAITEQKQ 976
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALE---RRIAALARRIRALEQELAALEAELAELEKEIAE 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  977 kmrrlgsdltsAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQL-RAQGGSSDSSLALHERIQALEAELQAVS 1055
Cdd:COG4942     95 -----------LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAvRRLQYLKYLAPARREQAEELRADLAELA 163
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1955007392 1056 HSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALRE 1133
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
621-844 9.63e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 9.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  621 SQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEdLQRRLEEFEGE----RERLQRMADSAASLEQ 696
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAA-LARRIRALEQElaalEAELAELEKEIAELRA 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  697 QLEQVKLTLlqrDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKI 776
Cdd:COG4942     98 ELEAQKEEL---AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1955007392  777 ILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQ 844
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
619-904 9.74e-05

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 46.94  E-value: 9.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  619 SLSQQLTETQHRSMKEKG---RIAAQLQgiEADMLDQEAAFMQIQEAktmveEDLQRRLEEFEGERERlqrmadsaasle 695
Cdd:pfam05667  230 GLASRLTPEEYRKRKRTKllkRIAEQLR--SAALAGTEATSGASRSA-----QDLAELLSSFSGSSTT------------ 290
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  696 qQLEQVKLTLLQRDQQLeALQQEHLDLMKQLTLT----QEALQSREQSLDALQTHYDELQARLGELQGEAASREDTIclL 771
Cdd:pfam05667  291 -DTGLTKGSRFTHTEKL-QFTNEAPAATSSPPTKveteEELQQQREEELEELQEQLEDLESSIQELEKEIKKLESSI--K 366
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  772 QnekiiLEAALQAAKSGKEELdrgarrleegtEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKV- 850
Cdd:pfam05667  367 Q-----VEEELEELKEQNEEL-----------EKQYKVKKKTLDLLPDAEENIAKLQALVDASAQRLVELAGQWEKHRVp 430
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1955007392  851 MVEAYRRDATSKDQliSELKATRKRldSELKELRQELMQVHGEKRTAEAELSRL 904
Cdd:pfam05667  431 LIEEYRALKEAKSN--KEDESQRKL--EEIKELREKIKEVAEEAKQKEELYKQL 480
46 PHA02562
endonuclease subunit; Provisional
1043-1260 1.19e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.55  E-value: 1.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1043 RIQALEAELQAVSHSKTLLE-------KELQEVIALTSQELEESREKVlelEDELQESRGFRKKIKRLEESNKKLALELE 1115
Cdd:PHA02562   175 KIRELNQQIQTLDMKIDHIQqqiktynKNIEEQRKKNGENIARKQNKY---DELVEEAKTIKAEIEELTDELLNLVMDIE 251
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1116 HEKGKLTGLGQSNAALREhnsilETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHL---VQALQASLEKEKEKVNSLK 1192
Cdd:PHA02562   252 DPSAALNKLNTAAAKIKS-----KIEQFQKVIKMYEKGGVCPTCTQQISEGPDRITKIkdkLKELQHSLEKLDTAIDELE 326
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1955007392 1193 EQVaaakVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELAE 1260
Cdd:PHA02562   327 EIM----DEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDK 390
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
824-1448 1.30e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 1.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  824 VEHLQQETAAlKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLiSELKATRKRLDSELKELRQELmqvhgekrtAEAELSR 903
Cdd:COG4913    231 VEHFDDLERA-HEALEDAREQIELLEPIRELAERYAAARERL-AELEYLRAALRLWFAQRRLEL---------LEAELEE 299
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  904 LHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEqmvavteanEALKKQIEELQQEARK---AITEQKQKMRR 980
Cdd:COG4913    300 LRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRL---------EQLEREIERLERELEErerRRARLEALLAA 370
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  981 LGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRaqggssdsslalhERIQALEAELQAVSHSKTL 1060
Cdd:COG4913    371 LGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR-------------RELRELEAEIASLERRKSN 437
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1061 LEKELQEVIALTSQELEESREKVL---ELEDELQESRGFRKKIKRL----------EESNKKLALEL---EHEKGKLTGL 1124
Cdd:COG4913    438 IPARLLALRDALAEALGLDEAELPfvgELIEVRPEEERWRGAIERVlggfaltllvPPEHYAAALRWvnrLHLRGRLVYE 517
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1125 GqsnAALREHNSILETALAKREADLVQLNLQ-----VQAVLQRKE-----EEDRQMKHLVQALQASLekekekvnslkeQ 1194
Cdd:COG4913    518 R---VRTGLPDPERPRLDPDSLAGKLDFKPHpfrawLEAELGRRFdyvcvDSPEELRRHPRAITRAG------------Q 582
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1195 VAAAKVEAGHNRRHFKAASLEL-SEVKKELQAKEHLVQKLQAEADDLQiregkhsQEIAQFQAELAEARAQLQLLqkqld 1273
Cdd:COG4913    583 VKGNGTRHEKDDRRRIRSRYVLgFDNRAKLAALEAELAELEEELAEAE-------ERLEALEAELDALQERREAL----- 650
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1274 eqlskqpvgnQEMENLKWE---VDQKEREIQSLKQQLDLTEQqGRKELEGLQQllqnvksELEMAQEDLSMTQKDKFMLQ 1350
Cdd:COG4913    651 ----------QRLAEYSWDeidVASAEREIAELEAELERLDA-SSDDLAALEE-------QLEELEAELEELEEELDELK 712
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1351 AKVSELKNNMKtllqqnqqlKLDLRRGAAKTRKEPKGEASSSNPATpikipdcpvpasLLEELLR--PPPAVSKEPLKNL 1428
Cdd:COG4913    713 GEIGRLEKELE---------QAEEELDELQDRLEAAEDLARLELRA------------LLEERFAaaLGDAVERELRENL 771
                          650       660
                   ....*....|....*....|
gi 1955007392 1429 NSCLQQLKQEMDSLQRQMEE 1448
Cdd:COG4913    772 EERIDALRARLNRAEEELER 791
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
947-1199 1.42e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 1.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  947 VAVTEANEALKKQIEELQQEarkaITEQKQKMRRLGSDLTSAQKEMktkhKAYENAVGILSRRLQEALAAKEAADAELGQ 1026
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQE----IAELEKELAALKKEEKALLKQL----AALERRIAALARRIRALEQELAALEAELAE 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1027 LRAQggssdsslalherIQALEAELQAvshsktlLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEES 1106
Cdd:COG4942     88 LEKE-------------IAELRAELEA-------QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPA 147
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1107 NKKLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKE 1186
Cdd:COG4942    148 RREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
                          250
                   ....*....|...
gi 1955007392 1187 KVNSLKEQVAAAK 1199
Cdd:COG4942    228 LIARLEAEAAAAA 240
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
824-1208 2.10e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.12  E-value: 2.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  824 VEHLQQETAALKKQMQKIKEqflqqkvmvEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSR 903
Cdd:pfam02463  153 ERRLEIEEEAAGSRLKRKKK---------EALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEE 223
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  904 LHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGS 983
Cdd:pfam02463  224 EYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELL 303
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  984 DLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQggssdsSLALHERIQALEAELQavsHSKTLLEK 1063
Cdd:pfam02463  304 KLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIK------REAEEEEEEELEKLQE---KLEQLEEE 374
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1064 ELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALREHNSILETALA 1143
Cdd:pfam02463  375 LLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELE 454
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1955007392 1144 KREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRH 1208
Cdd:pfam02463  455 KQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDG 519
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
695-975 2.17e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.78  E-value: 2.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  695 EQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNE 774
Cdd:TIGR04523  369 QNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQ 448
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  775 KIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEA 854
Cdd:TIGR04523  449 DSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEK 528
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  855 YRRDATSKDQLISELKATRKRLDSELKELRQElmqvhGEKRTAEAELSRLHREvaqvrqhmadlEGHLQSAQKERDEMET 934
Cdd:TIGR04523  529 LESEKKEKESKISDLEDELNKDDFELKKENLE-----KEIDEKNKEIEELKQT-----------QKSLKKKQEEKQELID 592
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1955007392  935 HLQSLQFD-KEQMVAVTEANEALKKQIEELQQEARKAITEQK 975
Cdd:TIGR04523  593 QKEKEKKDlIKEIEEKEKKISSLEKELEKAKKENEKLSSIIK 634
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
893-1117 2.31e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 2.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  893 EKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLqfdkEQMVAVTEAN-EALKKQIEELQQEARKAI 971
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL----ARRIRALEQElAALEAELAELEKEIAELR 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  972 TEQKQKMRRLGSDLTSAQKEMKTKHKAY---ENAVGILSRRLQEALAAKEAADAELGQLRAQggssdsslalHERIQALE 1048
Cdd:COG4942     97 AELEAQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRAD----------LAELAALR 166
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1955007392 1049 AELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHE 1117
Cdd:COG4942    167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
828-1362 2.35e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.73  E-value: 2.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  828 QQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQ----VHGEKRTAEAELSR 903
Cdd:TIGR00618  151 QGEFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCmpdtYHERKQVLEKELKH 230
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  904 LHREVAQVRQHMADLEgHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEAR-----KAITEQKQKM 978
Cdd:TIGR00618  231 LREALQQTQQSHAYLT-QKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPlaahiKAVTQIEQQA 309
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  979 RRLGSDLTSaQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSK 1058
Cdd:TIGR00618  310 QRIHTELQS-KMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQK 388
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1059 TLLEKELQeviaLTSQELEESREKVLELEDELQESRGFRKKIKRLEE----SNKKLALELEHEKGKLTGLGQSNAALREH 1134
Cdd:TIGR00618  389 TTLTQKLQ----SLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKqqelQQRYAELCAAAITCTAQCEKLEKIHLQES 464
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1135 NSILEtALAKREADLVQLNLQVQ-------AVLQRKEEEDRQMK----HLVQALQAS-------------------LEKE 1184
Cdd:TIGR00618  465 AQSLK-EREQQLQTKEQIHLQETrkkavvlARLLELQEEPCPLCgsciHPNPARQDIdnpgpltrrmqrgeqtyaqLETS 543
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1185 KEKV----NSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADD----------------LQIRE 1244
Cdd:TIGR00618  544 EEDVyhqlTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKlseaedmlaceqhallRKLQP 623
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1245 GKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPV-----GNQEMENLKWEVDQ-KEREIQSLKQQLDlteqqgrKEL 1318
Cdd:TIGR00618  624 EQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVrehalSIRVLPKELLASRQlALQKMQSEKEQLT-------YWK 696
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1955007392 1319 EGLQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELKNNMKT 1362
Cdd:TIGR00618  697 EMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDA 740
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1174-1395 2.46e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 2.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1174 VQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQ 1253
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1254 FQAELAEARAQLQLLQKQLDEQLSKQPVG---NQE--------MENLKWEVDQKEREIQSLKQQLDLTEQQgRKELEGLQ 1322
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLAlllSPEdfldavrrLQYLKYLAPARREQAEELRADLAELAAL-RAELEAER 173
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1955007392 1323 QLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRGAAKTRKEPKGEASSSNPA 1395
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
654-1043 2.78e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.71  E-value: 2.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  654 AAFMQIQ-EAKTMVEEDLQRRLEEFEG------ERERLQRMADSAASLEQqleqvkltllqRDQQLEALQQ---EHLDLM 723
Cdd:COG3096    271 ADYMRHAnERRELSERALELRRELFGArrqlaeEQYRLVEMARELEELSA-----------RESDLEQDYQaasDHLNLV 339
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  724 KQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGA------- 796
Cdd:COG3096    340 QTALRQQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAiqyqqav 419
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  797 ---RRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQM---QKIKEQF-----LQQKVMVEAYRRDATSK-DQ 864
Cdd:COG3096    420 qalEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLsvaDAARRQFekayeLVCKIAGEVERSQAWQTaRE 499
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  865 LISE------LKATRKRLDSELKELRQELMQvhgeKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQS 938
Cdd:COG3096    500 LLRRyrsqqaLAQRLQQLRAQLAELEQRLRQ----QQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAE 575
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  939 LQfdkEQMVAVTEANEALKKQIEELQQEARKAITEQkQKMRRL----GSDLTSAQKEMKTKHKAYENAVGILSRRLQEAL 1014
Cdd:COG3096    576 AV---EQRSELRQQLEQLRARIKELAARAPAWLAAQ-DALERLreqsGEALADSQEVTAAMQQLLEREREATVERDELAA 651
                          410       420       430
                   ....*....|....*....|....*....|
gi 1955007392 1015 AAKEAADAELgQLRAQGGSSDSSL-ALHER 1043
Cdd:COG3096    652 RKQALESQIE-RLSQPGGAEDPRLlALAER 680
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
873-1323 2.81e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.71  E-value: 2.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  873 RKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAqkerdemETHLQSLQfdkeQMVAVTEA 952
Cdd:COG3096    280 RRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAA-------SDHLNLVQ----TALRQQEK 348
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  953 NEALKKQIEEL------QQEARKAITEQKQkMRRLGSDLTSAQ-KEMKTKHKAYENAVGILSRRlqealaakeaadaelg 1025
Cdd:COG3096    349 IERYQEDLEELterleeQEEVVEEAAEQLA-EAEARLEAAEEEvDSLKSQLADYQQALDVQQTR---------------- 411
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1026 qlraqggssdsSLALHERIQALEaELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEE 1105
Cdd:COG3096    412 -----------AIQYQQAVQALE-KARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYE 479
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1106 SNKKLALELEHEkgklTGLGQSNAALREHNSilETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQAS----- 1180
Cdd:COG3096    480 LVCKIAGEVERS----QAWQTARELLRRYRS--QQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQldaae 553
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1181 -LEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREG---KHSQEIAQFQA 1256
Cdd:COG3096    554 eLEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGealADSQEVTAAMQ 633
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1955007392 1257 ELAEaraqlqllqkqldeqlskqpvgnqemenlkwevdqKEREIQSLKQQLDLTEQQGRKELEGLQQ 1323
Cdd:COG3096    634 QLLE-----------------------------------REREATVERDELAARKQALESQIERLSQ 665
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1040-1322 3.28e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 3.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1040 LHERIQALEAELQAvshsktllEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKG 1119
Cdd:PRK03918   174 IKRRIERLEKFIKR--------TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEK 245
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1120 KLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAV--LQRKEEEDRQMKHLVQALQ---ASLEKEKEKVNSLKEQ 1194
Cdd:PRK03918   246 ELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELkeLKEKAEEYIKLSEFYEEYLdelREIEKRLSRLEEEING 325
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1195 VAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQaEADDLQIREGKHSQEIAQFQAELAEARAqlqllqkqlde 1274
Cdd:PRK03918   326 IEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYE-EAKAKKEELERLKKRLTGLTPEKLEKEL----------- 393
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1955007392 1275 qlskqpvgnQEMENLKWEVDQKEREIQSLKQQLDLTEQQGRKELEGLQ 1322
Cdd:PRK03918   394 ---------EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELK 432
mukB PRK04863
chromosome partition protein MukB;
668-1005 4.03e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.33  E-value: 4.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  668 EDLQRRLEEFEGERERLQRMADSAASL-------------EQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQ 734
Cdd:PRK04863   796 EELAERYATLSFDVQKLQRLHQAFSRFigshlavafeadpEAELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLS 875
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  735 SREQSLDALQTHYDE-LQARLGELQGEaasredticllqnekiiLEAALQAAKSgkeeldrgARRLEEGTEETSETLEKL 813
Cdd:PRK04863   876 ALNRLLPRLNLLADEtLADRVEEIREQ-----------------LDEAEEAKRF--------VQQHGNALAQLEPIVSVL 930
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  814 REELAiksgQVEHLQQETAALKKQMQKIKEQFLQQKVMVEayRRDATSKDQLISELKAtrkrlDSELKE-LRQELMQVHG 892
Cdd:PRK04863   931 QSDPE----QFEQLKQDYQQAQQTQRDAKQQAFALTEVVQ--RRAHFSYEDAAEMLAK-----NSDLNEkLRQRLEQAEQ 999
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  893 EKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFdkeqmVAVTEANEALKKQIEELQQEAR---- 968
Cdd:PRK04863  1000 ERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGV-----PADSGAEERARARRDELHARLSanrs 1074
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1955007392  969 ------KAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGI 1005
Cdd:PRK04863  1075 rrnqleKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKAG 1117
mukB PRK04863
chromosome partition protein MukB;
873-1245 4.27e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.95  E-value: 4.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  873 RKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQslQFDKEQM--VAVT 950
Cdd:PRK04863   281 RRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALR--QQEKIERyqADLE 358
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  951 EANEALkkqieELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRR-LQEALAAKEAAdaelgqlRA 1029
Cdd:PRK04863   359 ELEERL-----EEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRaIQYQQAVQALE-------RA 426
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1030 QGGSSDSSLALH---ERIQALEAELQAVSHSKTLLEKELQEVIALTSQeLEESREKVLELEDELQESRG---FRKKIKRL 1103
Cdd:PRK04863   427 KQLCGLPDLTADnaeDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQ-FEQAYQLVRKIAGEVSRSEAwdvARELLRRL 505
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1104 EESnKKLALELEHEKGKLTGLGQS-------NAALREHN----------SILETALAKREADLVQLNLQVQAVLQRKEEE 1166
Cdd:PRK04863   506 REQ-RHLAEQLQQLRMRLSELEQRlrqqqraERLLAEFCkrlgknlddeDELEQLQEELEARLESLSESVSEARERRMAL 584
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1167 DRQMKHLvQALQASLEKE-------KEKVNSLKEQVAAAkVEAGHNRRHFKAASLE----LSEVKKELQAKEhlvQKLQA 1235
Cdd:PRK04863   585 RQQLEQL-QARIQRLAARapawlaaQDALARLREQSGEE-FEDSQDVTEYMQQLLErereLTVERDELAARK---QALDE 659
                          410
                   ....*....|
gi 1955007392 1236 EADDLQIREG 1245
Cdd:PRK04863   660 EIERLSQPGG 669
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
861-1356 4.51e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 4.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  861 SKDQLISELKATRKRLDSELKELRQELmqvhGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMEtHLQSLQ 940
Cdd:COG4717     54 EADELFKPQGRKPELNLKELKELEEEL----KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLE-KLLQLL 128
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  941 FDKEQMVAVTEANEALKKQIEELQQEaRKAITEQKQKMRRLGSDLTSAQKEMKTKHKayenavgilsrrlqealaakeaa 1020
Cdd:COG4717    129 PLYQELEALEAELAELPERLEELEER-LEELRELEEELEELEAELAELQEELEELLE----------------------- 184
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1021 daelgqlraqggssDSSLALHERIQALEAELQAVSHSKTLLEKELQEVialtSQELEESREKVLELEDELQESRgFRKKI 1100
Cdd:COG4717    185 --------------QLSLATEEELQDLAEELEELQQRLAELEEELEEA----QEELEELEEELEQLENELEAAA-LEERL 245
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1101 KRLEESNKKLALELEhekgkLTGLGQSNAALREHN-----------SILETALAKREADLVQLNLQVQAVLQRKEEEDRQ 1169
Cdd:COG4717    246 KEARLLLLIAAALLA-----LLGLGGSLLSLILTIagvlflvlgllALLFLLLAREKASLGKEAEELQALPALEELEEEE 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1170 MKHLVQALQASLEKEKEKVNSLKEQVAAAKveaghnrrhfkAASLELSEVKKELQakehlVQKLQAEADDLQIREGKHSQ 1249
Cdd:COG4717    321 LEELLAALGLPPDLSPEELLELLDRIEELQ-----------ELLREAEELEEELQ-----LEELEQEIAALLAEAGVEDE 384
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1250 EIAQFQAELAEARAQLQLLQKQLDEQLSKQPvGNQEMENLKWEVDQKEREIQSLKQQLDLTEqqgrKELEGLQQLLQNVK 1329
Cdd:COG4717    385 EELRAALEQAEEYQELKEELEELEEQLEELL-GELEELLEALDEEELEEELEELEEELEELE----EELEELREELAELE 459
                          490       500
                   ....*....|....*....|....*....
gi 1955007392 1330 SELEMAQED--LSMTQKDKFMLQAKVSEL 1356
Cdd:COG4717    460 AELEQLEEDgeLAELLQELEELKAELREL 488
PRK11281 PRK11281
mechanosensitive channel MscK;
367-638 5.16e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.90  E-value: 5.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  367 AAAAEHQDQGQEvnGEVRSRRDSICSSVSLESSAAETQ---EEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLA 443
Cdd:PRK11281    27 ARAASNGDLPTE--ADVQAQLDALNKQKLLEAEDKLVQqdlEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELE 104
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  444 ALSTKLQAQVecshssQQRQDSLSseVDTLKQSCWDLERAMTDLQNMLEAKNASLASsnndLQVAEEQYQRLMAkvEDMQ 523
Cdd:PRK11281   105 ALKDDNDEET------RETLSTLS--LRQLESRLAQTLDQLQNAQNDLAEYNSQLVS----LQTQPERAQAALY--ANSQ 170
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  524 RSM----------LSKDNTVHDLRQQMTALQSQLQQVQLERTTLTsklkasqAEISSLQSVrqwYQQQLALAQEARVRLQ 593
Cdd:PRK11281   171 RLQqirnllkggkVGGKALRPSQRVLLQAEQALLNAQNDLQRKSL-------EGNTQLQDL---LQKQRDYLTARIQRLE 240
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1955007392  594 GEMAHIQvgqmtqagllEHLKLENVSLSQQlTETQHRSMKEKGRI 638
Cdd:PRK11281   241 HQLQLLQ----------EAINSKRLTLSEK-TVQEAQSQDEAARI 274
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
582-798 5.51e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 5.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  582 LALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSQQLTETQhrsmKEKGRIAAQLQGIEADMLDQEAAFMQIQE 661
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALE----RRIAALARRIRALEQELAALEAELAELEK 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  662 AKTMVEEDLQRRLEEFEGERERLQRM-----------ADSAASLEQQLEQVKLTLLQRDQQLEALQQEhldlMKQLTLTQ 730
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRLgrqpplalllsPEDFLDAVRRLQYLKYLAPARREQAEELRAD----LAELAALR 166
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1955007392  731 EALQSREQSLDALQthyDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARR 798
Cdd:COG4942    167 AELEAERAELEALL---AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
823-981 7.64e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.99  E-value: 7.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  823 QVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQ-------ELMQVHGEKr 895
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEArikkyeeQLGNVRNNK- 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  896 taeaELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQfdkeqmvavtEANEALKKQIEELQQEARKAITEQK 975
Cdd:COG1579     90 ----EYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELE----------AELAELEAELEEKKAELDEELAELE 155

                   ....*.
gi 1955007392  976 QKMRRL 981
Cdd:COG1579    156 AELEEL 161
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
835-1008 8.34e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 44.27  E-value: 8.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  835 KKQMQKIKEQFLQQK----VMVEAY-------RRDATSKD--QLISELKATRKRLDSELKELRQELMQVHGEKRTAEAEL 901
Cdd:TIGR01612 1506 AKAIEKNKELFEQYKkdvtELLNKYsalaiknKFAKTKKDseIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDA 1585
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  902 S---RLHREVAQVRQHMADLEGHL----------QSAQKERDEMETHLQSLQFDKE--QMVAVTEANEALKKQIEELQQE 966
Cdd:TIGR01612 1586 AkndKSNKAAIDIQLSLENFENKFlkisdikkkiNDCLKETESIEKKISSFSIDSQdtELKENGDNLNSLQEFLESLKDQ 1665
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1955007392  967 aRKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYEnaVGILSR 1008
Cdd:TIGR01612 1666 -KKNIEDKKKELDELDSEIEKIEIDVDQHKKNYE--IGIIEK 1704
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
394-1261 9.07e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.01  E-value: 9.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  394 VSLESSAAETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVDTL 473
Cdd:pfam01576  225 AELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEAL 304
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  474 KqscwdleramTDLQNMLEAKNAslassNNDLQVAEEQYQRLMAKVedMQRSMLSKDNTVHDLRQQMTALQSqlqqvqle 553
Cdd:pfam01576  305 K----------TELEDTLDTTAA-----QQELRSKREQEVTELKKA--LEEETRSHEAQLQEMRQKHTQALE-------- 359
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  554 rtTLTSKLKASQAEISSLQSVRQwyqqqlALAQEaRVRLQGEMAhiqvgqmtqagllehlklenvSLSQQLTETQHRsmk 633
Cdd:pfam01576  360 --ELTEQLEQAKRNKANLEKAKQ------ALESE-NAELQAELR---------------------TLQQAKQDSEHK--- 406
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  634 eKGRIAAQLQGIEADMLDQEAAFMQIQE--AKTMVE-EDLQRRLEEFEGERERLQRmadSAASLEQQLEQVKLTLLQRDQ 710
Cdd:pfam01576  407 -RKKLEGQLQELQARLSESERQRAELAEklSKLQSElESVSSLLNEAEGKNIKLSK---DVSSLESQLQDTQELLQEETR 482
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  711 Q-------LEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQ 783
Cdd:pfam01576  483 QklnlstrLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLE 562
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  784 AAKSGKEELDRGARRleegteetsetlekLREELAIKSGQVEHLQQETAALKKQMQK----------IKEQFLQQKVMVE 853
Cdd:pfam01576  563 EKAAAYDKLEKTKNR--------------LQQELDDLLVDLDHQRQLVSNLEKKQKKfdqmlaeekaISARYAEERDRAE 628
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  854 AYRRD----ATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTA-----EAELSR--LHREVAQVRQHMADLEGHL 922
Cdd:pfam01576  629 AEAREketrALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVgknvhELERSKraLEQQVEEMKTQLEELEDEL 708
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  923 QSAQKERDEMETHLQSL--QFDKEqMVAVTEANE----ALKKQIEELQ---QEARKAITEQKQKMRRLGSDLTSAQKEMK 993
Cdd:pfam01576  709 QATEDAKLRLEVNMQALkaQFERD-LQARDEQGEekrrQLVKQVRELEaelEDERKQRAQAVAAKKKLELDLKELEAQID 787
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  994 TKHKAYENAVGILsRRLQEALAAKEAADAELGQLRAQGGSsdSSLALHERIQALEAELQavshsktllekELQEVIALTS 1073
Cdd:pfam01576  788 AANKGREEAVKQL-KKLQAQMKDLQRELEEARASRDEILA--QSKESEKKLKNLEAELL-----------QLQEDLAASE 853
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1074 QELEESREKVLELEDEL-----------QESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALREHNSILETAL 1142
Cdd:pfam01576  854 RARRQAQQERDELADEIasgasgksalqDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTS 933
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1143 AKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKekeKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKE 1222
Cdd:pfam01576  934 QKSESARQQLERQNKELKAKLQEMEGTVKSKFKSSIAALEA---KIAQLEEQLEQESRERQAANKLVRRTEKKLKEVLLQ 1010
                          890       900       910       920
                   ....*....|....*....|....*....|....*....|.
gi 1955007392 1223 LQAKEHLVQ--KLQAEADDLQIREGKHSQEIAQFQAELAEA 1261
Cdd:pfam01576 1011 VEDERRHADqyKDQAEKGNSRMKQLKRQLEEAEEEASRANA 1051
PRK09039 PRK09039
peptidoglycan -binding protein;
393-524 1.04e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.03  E-value: 1.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  393 SVSLESSAAETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAAlstklQAQVecSHSSQQRQDSLSSEVDT 472
Cdd:PRK09039    76 NQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQELDS-----EKQV--SARALAQVELLNQQIAA 148
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1955007392  473 LKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAeeqyqrLMAKVEDMQR 524
Cdd:PRK09039   149 LRRQLAALEAALDASEKRDRESQAKIADLGRRLNVA------LAQRVQELNR 194
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
423-990 1.16e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 43.59  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  423 ALSLEASQALKEKAELQA----QLAALSTKLQAQVECSHSSQQRQDSLSSEVDTLKqscwdleRAMTDLQNMLEAKNASL 498
Cdd:pfam07111   52 SLELEGSQALSQQAELISrqlqELRRLEEEVRLLRETSLQQKMRLEAQAMELDALA-------VAEKAGQAEAEGLRAAL 124
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  499 ASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDlrqqmtalqsqlqqvqLERTTLTSKLKASQAEISSLQSVRQWY 578
Cdd:pfam07111  125 AGAEMVRKNLEEGSQRELEEIQRLHQEQLSSLTQAHE----------------EALSSLTSKAEGLEKSLNSLETKRAGE 188
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  579 QQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKlenVSLSQQLTETQHRSM--KEKGRIAAQLQGIEADMLDqeaaf 656
Cdd:pfam07111  189 AKQLAEAQKEAELLRKQLSKTQEELEAQVTLVESLR---KYVGEQVPPEVHSQTweLERQELLDTMQHLQEDRAD----- 260
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  657 mqIQEAKTMVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQ--------QLEALQQEHLDLMKQltl 728
Cdd:pfam07111  261 --LQATVELLQVRVQSLTHMLALQEEELTRKIQPSDSLEPEFPKKCRSLLNRWRekvfalmvQLKAQDLEHRDSVKQ--- 335
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  729 tqealqsreqsldalqthydelqarlgeLQGEAASREDTICLLQNEKIILEAALQaAKSGKEELDRgarrleegteetse 808
Cdd:pfam07111  336 ----------------------------LRGQVAELQEQVTSQSQEQAILQRALQ-DKAAEVEVER-------------- 372
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  809 tleklreeLAIKSGQVEhLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELM 888
Cdd:pfam07111  373 --------MSAKGLQME-LSRAQEARRRQQQQTASAEEQLKFVVNAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVR 443
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  889 QVHGEKRTAEAELSrlhreVAQVRQHM-----------ADLEGHLQSAQKERDEMETHLQ-SLQFDKEQMVAVTEANEAL 956
Cdd:pfam07111  444 KVHTIKGLMARKVA-----LAQLRQEScpppppappvdADLSLELEQLREERNRLDAELQlSAHLIQQEVGRAREQGEAE 518
                          570       580       590
                   ....*....|....*....|....*....|....
gi 1955007392  957 KKQIEELQQEARKAITEQKQKMRRLGSDLTSAQK 990
Cdd:pfam07111  519 RQQLSEVAQQLEQELQRAQESLASVGQQLEVARQ 552
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
487-764 1.31e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 1.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  487 LQNMLEAKNASLASSNNDLqvaEEQYQRLMAKVEDmqrsmlsKDNTVHDLRQQ--MTALQSQLQQVQLERTTLTSKLKAS 564
Cdd:COG3206    162 LEQNLELRREEARKALEFL---EEQLPELRKELEE-------AEAALEEFRQKngLVDLSEEAKLLLQQLSELESQLAEA 231
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  565 QAEISSLQSVRQWYQQQLALAQEARVRLQGEmahiQVGQMTQAGLLEhLKLENVSLSQQLTEtQHRSMKEkgriaaqlqg 644
Cdd:COG3206    232 RAELAEAEARLAALRAQLGSGPDALPELLQS----PVIQQLRAQLAE-LEAELAELSARYTP-NHPDVIA---------- 295
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  645 ieadmLDQeaafmQIQEAKTMVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEhldlmk 724
Cdd:COG3206    296 -----LRA-----QIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLERE------ 359
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 1955007392  725 qltltqealqsreqsLDALQTHYDELQARLGELQGEAASR 764
Cdd:COG3206    360 ---------------VEVARELYESLLQRLEEARLAEALT 384
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
673-1003 1.76e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.02  E-value: 1.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  673 RLEEFEGERERL-QRMADSAAS------LEQQLEQVKLTLLQ------RDQQLEALQQEHLDLMKQLTLTQEALQSREQS 739
Cdd:COG3096    786 RLEELRAERDELaEQYAKASFDvqklqrLHQAFSQFVGGHLAvafapdPEAELAALRQRRSELERELAQHRAQEQQLRQQ 865
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  740 LDALQthydELQARLGELQGEAASREDTIclLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSEtlekLREELAi 819
Cdd:COG3096    866 LDQLK----EQLQLLNKLLPQANLLADET--LADRLEELREELDAAQEAQAFIQQHGKALAQLEPLVAV----LQSDPE- 934
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  820 ksgQVEHLQQETAALKKQMQKIKEQFLQQKVMVEayRRDATSKDQLISELKATrkrldSELKE-LRQELMQVHGEKRTAE 898
Cdd:COG3096    935 ---QFEQLQADYLQAKEQQRRLKQQIFALSEVVQ--RRPHFSYEDAVGLLGEN-----SDLNEkLRARLEQAEEARREAR 1004
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  899 AELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLqfdkeQMVAVTEANEALKKQIEELQQEAR---------- 968
Cdd:COG3096   1005 EQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEEL-----GVQADAEAEERARIRRDELHEELSqnrsrrsqle 1079
                          330       340       350
                   ....*....|....*....|....*....|....*
gi 1955007392  969 KAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAV 1003
Cdd:COG3096   1080 KQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAK 1114
Filament pfam00038
Intermediate filament protein;
878-1094 1.91e-03

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 42.21  E-value: 1.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  878 SELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKE-----RDEMETHLQSLQFDKeQMVAVTEA 952
Cdd:pfam00038   54 KEIEDLRRQLDTLTVERARLQLELDNLRLAAEDFRQKYEDELNLRTSAENDlvglrKDLDEATLARVDLEA-KIESLKEE 132
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  953 NEALKKQIEELQQEARKAITEQKQKMRR---LGSDLTSAQKEMKTKHKAyenavgiLSRRLQEALAAKEAADAELGQLRA 1029
Cdd:pfam00038  133 LAFLKKNHEEEVRELQAQVSDTQVNVEMdaaRKLDLTSALAEIRAQYEE-------IAAKNREEAEEWYQSKLEELQQAA 205
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1955007392 1030 QGGSSDSSLALHE------RIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESR 1094
Cdd:pfam00038  206 ARNGDALRSAKEEitelrrTIQSLEIELQSLKKQKASLERQLAETEERYELQLADYQELISELEAELQETR 276
PRK12704 PRK12704
phosphodiesterase; Provisional
1189-1333 1.91e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 1.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1189 NSLKEQVAAAKVEAghnRRHFKAASLELSEVKKE--LQAKEHlVQKLQAEAD-DLQIREgkhsQEIAQFQAELAEARAQL 1265
Cdd:PRK12704    27 KIAEAKIKEAEEEA---KRILEEAKKEAEAIKKEalLEAKEE-IHKLRNEFEkELRERR----NELQKLEKRLLQKEENL 98
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1955007392 1266 QLLQKQLDEQlskqpvgNQEMENLKWEVDQKEREIQSLKQQLDLTEQQGRKELE---GL------QQLLQNVKSELE 1333
Cdd:PRK12704    99 DRKLELLEKR-------EEELEKKEKELEQKQQELEKKEEELEELIEEQLQELErisGLtaeeakEILLEKVEEEAR 168
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
875-1011 2.30e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 2.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  875 RLDSELKELRQELmqvhgekRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQF----DKEQMVAVT 950
Cdd:COG1579     14 ELDSELDRLEHRL-------KELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEArikkYEEQLGNVR 86
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1955007392  951 ------------EANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQ 1011
Cdd:COG1579     87 nnkeyealqkeiESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELE 159
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
1212-1343 2.50e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.96  E-value: 2.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1212 ASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKhSQEIAQFQAEL--AEARAQLQLLQKQLDEQLSKQPVGNQ-EMEN 1288
Cdd:COG1566     74 ARLDPTDLQAALAQAEAQLAAAEAQLARLEAELGA-EAEIAAAEAQLaaAQAQLDLAQRELERYQALYKKGAVSQqELDE 152
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1955007392 1289 LKWEVDQKEREIQSLKQQLDLTEQQ--GRKELEGLQQLLQNVKSELEMAQEDLSMTQ 1343
Cdd:COG1566    153 ARAALDAAQAQLEAAQAQLAQAQAGlrEEEELAAAQAQVAQAEAALAQAELNLARTT 209
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1161-1361 2.53e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.74  E-value: 2.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1161 QRKEEEDRQMKHLVQAL---QASLEKEKEKVNSLKEQVAAAKveaghnrrHFKAASLELSEVKKELQAKEhlVQKLQAEA 1237
Cdd:TIGR02168  172 ERRKETERKLERTRENLdrlEDILNELERQLKSLERQAEKAE--------RYKELKAELRELELALLVLR--LEELREEL 241
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1238 DDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLdlteQQGRKE 1317
Cdd:TIGR02168  242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL----ANLERQ 317
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 1955007392 1318 LEGLQQLLQNVKSELEMAQEDLSMtqkdkfmLQAKVSELKNNMK 1361
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAE-------LEEKLEELKEELE 354
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
827-1356 2.55e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.40  E-value: 2.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  827 LQQETAALKKQMqKIKEQFLQQKVMVEAYRRDATSKDQLIS-------ELKATRKRLDSELKELRQELMQVHGEKRTAEA 899
Cdd:pfam05483  204 VQAENARLEMHF-KLKEDHEKIQHLEEEYKKEINDKEKQVSllliqitEKENKMKDLTFLLEESRDKANQLEEKTKLQDE 282
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  900 ELSRLHREVAQVRQHMADLEGHLQSAQKERDEMEthlQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMR 979
Cdd:pfam05483  283 NLKELIEKKDHLTKELEDIKMSLQRSMSTQKALE---EDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTC 359
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  980 RLGSDLTSAQKEMKTKhkayENAVGILSRRLQEALAakeaadaelgQLRAQGGSSDSSLALHERIQALEAELQAVSHSKT 1059
Cdd:pfam05483  360 SLEELLRTEQQRLEKN----EDQLKIITMELQKKSS----------ELEEMTKFKNNKEVELEELKKILAEDEKLLDEKK 425
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1060 LLEKeLQEVIALTSQELE---ESREKvlELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALREHNS 1136
Cdd:pfam05483  426 QFEK-IAEELKGKEQELIfllQAREK--EIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENK 502
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1137 iletALAKREADLV-QLNLQVQAVLQRKEEEDRQMKHL--VQALQASLEKEKEKV-NSLKEQVAAAKVEAGHNRRHFKAA 1212
Cdd:pfam05483  503 ----ELTQEASDMTlELKKHQEDIINCKKQEERMLKQIenLEEKEMNLRDELESVrEEFIQKGDEVKCKLDKSEENARSI 578
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1213 SLELSEVKKELQAKEHLVQKLQAEADDlqirEGKHSQEIAQFQAELAEaraqlqllqkqldeqlsKQPVGNQEMENLKWE 1292
Cdd:pfam05483  579 EYEVLKKEKQMKILENKCNNLKKQIEN----KNKNIEELHQENKALKK-----------------KGSAENKQLNAYEIK 637
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1955007392 1293 VDQKEREIQSLKQQLDLTEQQGRKELE----GLQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSEL 1356
Cdd:pfam05483  638 VNKLELELASAKQKFEEIIDNYQKEIEdkkiSEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEM 705
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
1073-1333 3.15e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 41.87  E-value: 3.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1073 SQELEESREKVLELEDELQES--RGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALREHNSILE-TALAKREADL 1149
Cdd:COG5185    248 LAQTSDKLEKLVEQNTDLRLEklGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEEqLAAAEAEQEL 327
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1150 VQLNLQVQAVLQRKEEEDRQmkhLVQALQASLEKEKEKVNSLKEQVAAAKVEAghnrrHFKAASLELSEVKKEL-QAKEH 1228
Cdd:COG5185    328 EESKRETETGIQNLTAEIEQ---GQESLTENLEAIKEEIENIVGEVELSKSSE-----ELDSFKDTIESTKESLdEIPQN 399
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1229 LVQKLQAEADDLQIREGKHSQEIAQFQAELAEAR-----AQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSL 1303
Cdd:COG5185    400 QRGYAQEILATLEDTLKAADRQIEELQRQIEQATssneeVSKLLNELISELNKVMREADEESQSRLEEAYDEINRSVRSK 479
                          250       260       270
                   ....*....|....*....|....*....|
gi 1955007392 1304 KQQLDLTEQQGRKELEGLQQLLQNVKSELE 1333
Cdd:COG5185    480 KEDLNEELTQIESRVSTLKATLEKLRAKLE 509
ATG16 pfam08614
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ...
417-515 3.30e-03

Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.


Pssm-ID: 462536 [Multi-domain]  Cd Length: 176  Bit Score: 40.30  E-value: 3.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  417 LEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNA 496
Cdd:pfam08614   55 LEQLLAQLREELAELYRSRGELAQRLVDLNEELQELEKKLREDERRLAALEAERAQLEEKLKDREEELREKRKLNQDLQD 134
                           90
                   ....*....|....*....
gi 1955007392  497 SLASSNNDLQVAEEQYQRL 515
Cdd:pfam08614  135 ELVALQLQLNMAEEKLRKL 153
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
823-1011 4.81e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.54  E-value: 4.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  823 QVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDatskdQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELS 902
Cdd:COG3206    169 RREEARKALEFLEEQLPELRKELEEAEAALEEFRQK-----NGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLA 243
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  903 RLHREVAQVRQHMADLEGH--LQSAQKERDEMETHLQSLQfdkeqmVAVTEAN---EALKKQIEELQQEARKAITEQKQK 977
Cdd:COG3206    244 ALRAQLGSGPDALPELLQSpvIQQLRAQLAELEAELAELS------ARYTPNHpdvIALRAQIAALRAQLQQEAQRILAS 317
                          170       180       190
                   ....*....|....*....|....*....|....
gi 1955007392  978 MRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQ 1011
Cdd:COG3206    318 LEAELEALQAREASLQAQLAQLEARLAELPELEA 351
PRK09039 PRK09039
peptidoglycan -binding protein;
813-965 5.16e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 40.72  E-value: 5.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  813 LREELAIKSGQVEHLQQETAALKKQ--MQKIKEQFLQQKVMVEAYRRDATSKDQ-----LISELKATRKRLDSELKELRQ 885
Cdd:PRK09039    44 LSREISGKDSALDRLNSQIAELADLlsLERQGNQDLQDSVANLRASLSAAEAERsrlqaLLAELAGAGAAAEGRAGELAQ 123
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  886 ELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQfdkeqmvavTEANEALKKQIEELQQ 965
Cdd:PRK09039   124 ELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEKRDRESQAKIADLG---------RRLNVALAQRVQELNR 194
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
813-1343 5.82e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 41.35  E-value: 5.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  813 LREELAIKSGQVEHLQQETAALKKQMQKIKE------QFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQE 886
Cdd:pfam10174  183 RTRRIAEAEMQLGHLEVLLDQKEKENIHLREelhrrnQLQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTN 262
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  887 LMqVHGEKRTAEA---ELSRLH-----REVAQVRQHMADLEGHLQSAQKERDEM-------ETHLQSLQFD---KEQMVA 948
Cdd:pfam10174  263 GL-LHTEDREEEIkqmEVYKSHskfmkNKIDQLKQELSKKESELLALQTKLETLtnqnsdcKQHIEVLKESltaKEQRAA 341
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  949 VTEAN-EALKKQIEELQQEARKAiTEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAakeaadaelgQL 1027
Cdd:pfam10174  342 ILQTEvDALRLRLEEKESFLNKK-TKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQE----------QL 410
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1028 RAQGGSSDSslaLHERIQALEAELQAVSHSKTLLEKELQE----VIALTSQELEESREKVLELEDelqesrgFRKKIKRL 1103
Cdd:pfam10174  411 RDKDKQLAG---LKERVKSLQTDSSNTDTALTTLEEALSEkeriIERLKEQREREDRERLEELES-------LKKENKDL 480
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1104 EEsnkklalELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQavlQRKEEEDRQMKHLVQALQASLEK 1183
Cdd:pfam10174  481 KE-------KVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVE---QKKEECSKLENQLKKAHNAEEAV 550
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1184 EK-----EKVNSLKEQVAAAKVEAGHNRrhfkaASLE-LSEVKKELQAKEHLVQKLQAEADDLQIREGK-HSQEIAQFQA 1256
Cdd:pfam10174  551 RTnpeinDRIRLLEQEVARYKEESGKAQ-----AEVErLLGILREVENEKNDKDKKIAELESLTLRQMKeQNKKVANIKH 625
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1257 elaearaqlqllqkqldeqlskqpvGNQEMENLKWEVDQKEReiqslKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQ 1336
Cdd:pfam10174  626 -------------------------GQQEMKKKGAQLLEEAR-----RREDNLADNSQQLQLEELMGALEKTRQELDATK 675

                   ....*..
gi 1955007392 1337 EDLSMTQ 1343
Cdd:pfam10174  676 ARLSSTQ 682
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
648-758 5.93e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.22  E-value: 5.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  648 DMLDQEAAFMQIqEAKTMVEE--DLQRRLEEFEGERERLQRMADS-----AASLEQQLEQVKltllqrdQQLEALQ---Q 717
Cdd:COG0542    393 DLIDEAAARVRM-EIDSKPEEldELERRLEQLEIEKEALKKEQDEasferLAELRDELAELE-------EELEALKarwE 464
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1955007392  718 EHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQ 758
Cdd:COG0542    465 AEKELIEEIQELKEELEQRYGKIPELEKELAELEEELAELA 505
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
396-1350 5.97e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 41.31  E-value: 5.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  396 LESSAAETQEEMLQVLKEKMRLEGQLEAlsleASQALKEKAELQAQLAALSTKLQaqvECSHSSQQRQDSLSSEVDTLKQ 475
Cdd:pfam01576   24 AESELKELEKKHQQLCEEKNALQEQLQA----ETELCAEAEEMRARLAARKQELE---EILHELESRLEEEEERSQQLQN 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  476 SCWDLERAMTDLQNMLEAKNASlassNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQM---TALQSQLQQVQL 552
Cdd:pfam01576   97 EKKKMQQHIQDLEEQLDEEEAA----RQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLeerISEFTSNLAEEE 172
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  553 ERTTLTSKLKASQ-AEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSQQLTETQHRS 631
Cdd:pfam01576  173 EKAKSLSKLKNKHeAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARL 252
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  632 MKEKGRIAAQLQGI---EADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQRMADSAASL-------EQQLEQV 701
Cdd:pfam01576  253 EEETAQKNNALKKIrelEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTAAQqelrskrEQEVTEL 332
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  702 KLTLLQR----DQQLEALQQEHL----DLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREdticllqN 773
Cdd:pfam01576  333 KKALEEEtrshEAQLQEMRQKHTqaleELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSE-------H 405
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  774 EKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFlqqkvmve 853
Cdd:pfam01576  406 KRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELL-------- 477
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  854 ayRRDATSKDQLISELKAtrkrLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEME 933
Cdd:pfam01576  478 --QEETRQKLNLSTRLRQ----LEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQ 551
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  934 THLQSLqfdKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKmRRLGSDLTSAQKEMKtKHKAYENAVG--ILSRRLQ 1011
Cdd:pfam01576  552 RELEAL---TQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQ-RQLVSNLEKKQKKFD-QMLAEEKAISarYAEERDR 626
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1012 EALAAKEAADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEK---ELQEVIALTSQELEESREKVLELED 1088
Cdd:pfam01576  627 AEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKnvhELERSKRALEQQVEEMKTQLEELED 706
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1089 ELQESRGFRKkikRLEESNKKLALELEHEKGKLTGLG-----QSNAALREHNSILE----------TALAKREADLVQLN 1153
Cdd:pfam01576  707 ELQATEDAKL---RLEVNMQALKAQFERDLQARDEQGeekrrQLVKQVRELEAELEderkqraqavAAKKKLELDLKELE 783
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1154 LQVQAVLQRKEEEDRQMKHLvQALQASLEKEKEKVNSLKEQVAAAKVEaghNRRHFKAASLELSEVKKELQAKEHLVQKL 1233
Cdd:pfam01576  784 AQIDAANKGREEAVKQLKKL-QAQMKDLQRELEEARASRDEILAQSKE---SEKKLKNLEAELLQLQEDLAASERARRQA 859
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1234 QAEADDLQI------------------------------------------REGKHSQEIAQFQAELAEARAQLQLLQKQ 1271
Cdd:pfam01576  860 QQERDELADeiasgasgksalqdekrrleariaqleeeleeeqsntellndRLRKSTLQVEQLTTELAAERSTSQKSESA 939
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1272 LDEQLSKQP---VGNQEMEN-------------------LKWEVDQKEREIQSLKQQLDLTE-----------------Q 1312
Cdd:pfam01576  940 RQQLERQNKelkAKLQEMEGtvkskfkssiaaleakiaqLEEQLEQESRERQAANKLVRRTEkklkevllqvederrhaD 1019
                         1050      1060      1070
                   ....*....|....*....|....*....|....*...
gi 1955007392 1313 QGRKELEGLQQLLQNVKSELEMAQEDLSMTQKDKFMLQ 1350
Cdd:pfam01576 1020 QYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQ 1057
PTZ00121 PTZ00121
MAEBL; Provisional
786-1323 6.79e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.28  E-value: 6.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  786 KSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKK--QMQKIKEQFLQQKV------------- 850
Cdd:PTZ00121  1073 KPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKaeDARKAEEARKAEDArkaeearkaedak 1152
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  851 MVEAYRRDATSKDQLISELKATRKRLDSELK--------ELRQ-------ELMQVHGEKRTAE----AELSRLHREVAQV 911
Cdd:PTZ00121  1153 RVEIARKAEDARKAEEARKAEDAKKAEAARKaeevrkaeELRKaedarkaEAARKAEEERKAEearkAEDAKKAEAVKKA 1232
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  912 RQHMADLEgHLQSAQKER--DEMETHLQSLQFDKEQMVAVTEANEALK----KQIEELQQ--EARKAitEQKQKMRRLGS 983
Cdd:PTZ00121  1233 EEAKKDAE-EAKKAEEERnnEEIRKFEEARMAHFARRQAAIKAEEARKadelKKAEEKKKadEAKKA--EEKKKADEAKK 1309
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  984 DLTSAQKEMKTKHKAYE-NAVGILSRRLQEALAAKEAADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLE 1062
Cdd:PTZ00121  1310 KAEEAKKADEAKKKAEEaKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEE 1389
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1063 KELQEVIALTSQELEESREKVLELEDELQESRGFRKK---IKRLEESNKKL-----ALELE---HEKGKLTGLGQSNAAL 1131
Cdd:PTZ00121  1390 KKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKaeeKKKADEAKKKAeeakkADEAKkkaEEAKKAEEAKKKAEEA 1469
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1132 REHNSILETALAKREADlvQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKV-EAGHNRRHFK 1210
Cdd:PTZ00121  1470 KKADEAKKKAEEAKKAD--EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKAdEAKKAEEKKK 1547
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1211 AASLELSEVKKELQAKEHLVQKLQAEAD-DLQIREGKHSQEIaqfqaelAEARAQLQLLQKQLDEQLSKQPVGNQEMENL 1289
Cdd:PTZ00121  1548 ADELKKAEELKKAEEKKKAEEAKKAEEDkNMALRKAEEAKKA-------EEARIEEVMKLYEEEKKMKAEEAKKAEEAKI 1620
                          570       580       590
                   ....*....|....*....|....*....|....
gi 1955007392 1290 KWEVDQKEREIQSLKQQLDLTEQQGRKELEGLQQ 1323
Cdd:PTZ00121  1621 KAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKK 1654
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
391-511 7.46e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 40.84  E-value: 7.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  391 CSSVSLESSAaeTQEEMLQVLKEKMRLEGQLEALSLEASQALKEK-AELQAQLAALSTKLQAQvecsHSSQQRQDSLSSE 469
Cdd:COG0542    399 AARVRMEIDS--KPEELDELERRLEQLEIEKEALKKEQDEASFERlAELRDELAELEEELEAL----KARWEAEKELIEE 472
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1955007392  470 VDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQ--VAEEQ 511
Cdd:COG0542    473 IQELKEELEQRYGKIPELEKELAELEEELAELAPLLReeVTEED 516
mukB PRK04863
chromosome partition protein MukB;
386-742 7.83e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.10  E-value: 7.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  386 RRDSICSSVSLESSAaETQEEMLQVLKEKMRLEGQLE----------ALSLEASQALKEKAELQAQLAALSTKLQAQVEC 455
Cdd:PRK04863   292 RRELYTSRRQLAAEQ-YRLVEMARELAELNEAESDLEqdyqaasdhlNLVQTALRQQEKIERYQADLEELEERLEEQNEV 370
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  456 SHSSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAknaslassnndLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHD 535
Cdd:PRK04863   371 VEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDV-----------QQTRAIQYQQAVQALERAKQLCGLPDLTADN 439
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  536 LRQQMTALQSQLQQVQLERTTLTSKLKASQAEISslqsvrqwyqqQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKL 615
Cdd:PRK04863   440 AEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHS-----------QFEQAYQLVRKIAGEVSRSEAWDVARELLRRLREQ 508
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  616 ENV-----SLSQQLTETQHRSMKEKG--RIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDL--------------QRRL 674
Cdd:PRK04863   509 RHLaeqlqQLRMRLSELEQRLRQQQRaeRLLAEFCKRLGKNLDDEDELEQLQEELEARLESLsesvsearerrmalRQQL 588
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1955007392  675 EEFEGERERLQRMA----DSAASLEQQLEQVKLTLLQRdQQLEALQQEHLDLMKQLTLTQEALQSREQSLDA 742
Cdd:PRK04863   589 EQLQARIQRLAARApawlAAQDALARLREQSGEEFEDS-QDVTEYMQQLLERERELTVERDELAARKQALDE 659
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
434-885 7.98e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.09  E-value: 7.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  434 EKAELQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVDtlkqscwdlerAMTDLQNMLEAknaslassnnDLQVAEEQYQ 513
Cdd:COG3096    279 ERRELSERALELRRELFGARRQLAEEQYRLVEMARELE-----------ELSARESDLEQ----------DYQAASDHLN 337
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  514 RLMAKV---EDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTsklkASQAEISSLQSVRQWYQQQLAlAQEARV 590
Cdd:COG3096    338 LVQTALrqqEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLE----AAEEEVDSLKSQLADYQQALD-VQQTRA 412
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  591 rlqgemahIQVGQMTQAgllehlkLENVSLSQQLTE-TQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEED 669
Cdd:COG3096    413 --------IQYQQAVQA-------LEKARALCGLPDlTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKA 477
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  670 LQrRLEEFEGERERLQRMADSAASLEQQLEQVKLTllqrdQQLEALQQEHLDLMKQLTLTQEALQSREQ----------S 739
Cdd:COG3096    478 YE-LVCKIAGEVERSQAWQTARELLRRYRSQQALA-----QRLQQLRAQLAELEQRLRQQQNAERLLEEfcqrigqqldA 551
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  740 LDALQTHYDELQARLGELQGEAASredticlLQNEKIILEAALQAAKSGKEELdrgaRRLEEGTEETSETLEKLREELAI 819
Cdd:COG3096    552 AEELEELLAELEAQLEELEEQAAE-------AVEQRSELRQQLEQLRARIKEL----AARAPAWLAAQDALERLREQSGE 620
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1955007392  820 ksgQVEHLQQETAALKKQMQKIKEQflqqkvmveayrrdATSKDQLIselkATRKRLDSELKELRQ 885
Cdd:COG3096    621 ---ALADSQEVTAAMQQLLEREREA--------------TVERDELA----ARKQALESQIERLSQ 665
COG4026 COG4026
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ...
1060-1177 8.82e-03

Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];


Pssm-ID: 443204 [Multi-domain]  Cd Length: 287  Bit Score: 40.10  E-value: 8.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1060 LLEKELQEVI---ALTS----QELEESREKVLELedelqesrgfRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALR 1132
Cdd:COG4026    107 LVRKEIKNAIiraGLKSlqniPEYNELREELLEL----------KEKIDEIAKEKEKLTKENEELESELEELREEYKKLR 176
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1955007392 1133 EHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQAL 1177
Cdd:COG4026    177 EENSILEEEFDNIKSEYSDLKSRFEELLKKRLLEVFSLEELWKEL 221
mukB PRK04863
chromosome partition protein MukB;
427-773 9.12e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 40.71  E-value: 9.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  427 EASQALKEKAELQAQLAALSTKLqaqvecsHSSQQRQDSLSSEVDtlkqscwDLERAMTDLQNMLEAKNASLASSNNDLQ 506
Cdd:PRK04863   280 ERRVHLEEALELRRELYTSRRQL-------AAEQYRLVEMARELA-------ELNEAESDLEQDYQAASDHLNLVQTALR 345
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  507 vAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQ 586
Cdd:PRK04863   346 -QQEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALE 424
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  587 EARVRLQ---------GEMAHIQVGQMTQAGlLEHLKLEN-VSLSQQLTETQHRSMKEKGRIAAQ--------------L 642
Cdd:PRK04863   425 RAKQLCGlpdltadnaEDWLEEFQAKEQEAT-EELLSLEQkLSVAQAAHSQFEQAYQLVRKIAGEvsrseawdvarellR 503
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  643 QGIEADMLDQ--EAAFMQIQEAKTMVEE--DLQRRLEEFEGereRLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQE 718
Cdd:PRK04863   504 RLREQRHLAEqlQQLRMRLSELEQRLRQqqRAERLLAEFCK---RLGKNLDDEDELEQLQEELEARLESLSESVSEARER 580
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1955007392  719 HLDLMKQltltQEALQSREQSLDALQTHYDELQ---ARLGELQGEA-ASREDTICLLQN 773
Cdd:PRK04863   581 RMALRQQ----LEQLQARIQRLAARAPAWLAAQdalARLREQSGEEfEDSQDVTEYMQQ 635
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
866-1161 9.71e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 40.27  E-value: 9.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  866 ISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQ 945
Cdd:COG4372     47 LEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQD 126
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392  946 MVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELG 1025
Cdd:COG4372    127 LEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAE 206
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955007392 1026 QLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEE 1105
Cdd:COG4372    207 KLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELE 286
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1955007392 1106 SNKKLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQ 1161
Cdd:COG4372    287 ALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADL 342
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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