NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1972290045|ref|NP_001379937|]
View 

RNA-binding protein pos-1 [Caenorhabditis elegans]

Protein Classification

zinc finger CCCH domain-containing protein( domain architecture ID 13416353)

zinc finger CCCH domain-containing protein similar to Arabidopsis thaliana zinc finger CCCH domain-containing protein 28

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
142-166 1.96e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 46.03  E-value: 1.96e-07
                          10        20
                  ....*....|....*....|....*
gi 1972290045 142 YKTVLCDKFSMTGNCKYGTRCQFIH 166
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAH 25
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
99-125 4.04e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


:

Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 45.26  E-value: 4.04e-07
                          10        20
                  ....*....|....*....|....*..
gi 1972290045  99 FKTALCDAYKRSQACSYGDQCRFAHGV 125
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
CTH1 super family cl34885
CCCH-type Zn-finger protein [General function prediction only];
47-222 7.52e-06

CCCH-type Zn-finger protein [General function prediction only];


The actual alignment was detected with superfamily member COG5063:

Pssm-ID: 227395 [Multi-domain]  Cd Length: 351  Bit Score: 46.58  E-value: 7.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972290045  47 SQDFQPFMKQD-KETQNSASQPTSEQSLANrdPCTVPDDLREEMMRQRRKEDafkTALCDAYKRSQACSY---GDQCRFA 122
Cdd:COG5063   180 DINLQPLSQRKpKSGKNCTSYTLGKESDAH--PHDELIYQKQEQNKPLYKTN---PELCESFTRKGTCPYwisGVKCQFA 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972290045 123 ---HGVHELRlpmnPRGRNHPkYKTVLCDKFSMTGNCKYGTRCQFIHkivdGNAAKLASGAHANTSSKS-PARNAAAhnH 198
Cdd:COG5063   255 crgHGLNELK----SKKKKQN-FRTEPCINWEKSGYCPYGLRCCFKH----GDDSDIEMYEEASLGYLDgPCRTRAK--G 323

                         170       180
                  ....*....|....*....|....*..
gi 1972290045 199 SLFVPQGSTDRSMD---LNQSLPIRQS 222
Cdd:COG5063   324 GAFPSGGAVCKSFDkknLDFSVKALQR 350
 
Name Accession Description Interval E-value
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
142-166 1.96e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 46.03  E-value: 1.96e-07
                          10        20
                  ....*....|....*....|....*
gi 1972290045 142 YKTVLCDKFSMTGNCKYGTRCQFIH 166
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAH 25
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
99-125 4.04e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 45.26  E-value: 4.04e-07
                          10        20
                  ....*....|....*....|....*..
gi 1972290045  99 FKTALCDAYKRSQACSYGDQCRFAHGV 125
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
ZnF_C3H1 smart00356
zinc finger;
141-166 2.34e-06

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 43.00  E-value: 2.34e-06
                           10        20
                   ....*....|....*....|....*.
gi 1972290045  141 KYKTVLCDKFsMTGNCKYGTRCQFIH 166
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAH 25
CTH1 COG5063
CCCH-type Zn-finger protein [General function prediction only];
47-222 7.52e-06

CCCH-type Zn-finger protein [General function prediction only];


Pssm-ID: 227395 [Multi-domain]  Cd Length: 351  Bit Score: 46.58  E-value: 7.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972290045  47 SQDFQPFMKQD-KETQNSASQPTSEQSLANrdPCTVPDDLREEMMRQRRKEDafkTALCDAYKRSQACSY---GDQCRFA 122
Cdd:COG5063   180 DINLQPLSQRKpKSGKNCTSYTLGKESDAH--PHDELIYQKQEQNKPLYKTN---PELCESFTRKGTCPYwisGVKCQFA 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972290045 123 ---HGVHELRlpmnPRGRNHPkYKTVLCDKFSMTGNCKYGTRCQFIHkivdGNAAKLASGAHANTSSKS-PARNAAAhnH 198
Cdd:COG5063   255 crgHGLNELK----SKKKKQN-FRTEPCINWEKSGYCPYGLRCCFKH----GDDSDIEMYEEASLGYLDgPCRTRAK--G 323

                         170       180
                  ....*....|....*....|....*..
gi 1972290045 199 SLFVPQGSTDRSMD---LNQSLPIRQS 222
Cdd:COG5063   324 GAFPSGGAVCKSFDkknLDFSVKALQR 350
ZnF_C3H1 smart00356
zinc finger;
99-124 1.15e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 38.38  E-value: 1.15e-04
                           10        20
                   ....*....|....*....|....*.
gi 1972290045   99 FKTALCDAYKRSQaCSYGDQCRFAHG 124
Cdd:smart00356   2 YKTELCKFFKRGY-CPRGDRCKFAHP 26
 
Name Accession Description Interval E-value
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
142-166 1.96e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 46.03  E-value: 1.96e-07
                          10        20
                  ....*....|....*....|....*
gi 1972290045 142 YKTVLCDKFSMTGNCKYGTRCQFIH 166
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAH 25
zf-CCCH pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar);
99-125 4.04e-07

Zinc finger C-x8-C-x5-C-x3-H type (and similar);


Pssm-ID: 459885 [Multi-domain]  Cd Length: 27  Bit Score: 45.26  E-value: 4.04e-07
                          10        20
                  ....*....|....*....|....*..
gi 1972290045  99 FKTALCDAYKRSQACSYGDQCRFAHGV 125
Cdd:pfam00642   1 YKTELCRFFLRTGYCKYGDRCKFAHGQ 27
ZnF_C3H1 smart00356
zinc finger;
141-166 2.34e-06

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 43.00  E-value: 2.34e-06
                           10        20
                   ....*....|....*....|....*.
gi 1972290045  141 KYKTVLCDKFsMTGNCKYGTRCQFIH 166
Cdd:smart00356   1 KYKTELCKFF-KRGYCPRGDRCKFAH 25
CTH1 COG5063
CCCH-type Zn-finger protein [General function prediction only];
47-222 7.52e-06

CCCH-type Zn-finger protein [General function prediction only];


Pssm-ID: 227395 [Multi-domain]  Cd Length: 351  Bit Score: 46.58  E-value: 7.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972290045  47 SQDFQPFMKQD-KETQNSASQPTSEQSLANrdPCTVPDDLREEMMRQRRKEDafkTALCDAYKRSQACSY---GDQCRFA 122
Cdd:COG5063   180 DINLQPLSQRKpKSGKNCTSYTLGKESDAH--PHDELIYQKQEQNKPLYKTN---PELCESFTRKGTCPYwisGVKCQFA 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972290045 123 ---HGVHELRlpmnPRGRNHPkYKTVLCDKFSMTGNCKYGTRCQFIHkivdGNAAKLASGAHANTSSKS-PARNAAAhnH 198
Cdd:COG5063   255 crgHGLNELK----SKKKKQN-FRTEPCINWEKSGYCPYGLRCCFKH----GDDSDIEMYEEASLGYLDgPCRTRAK--G 323

                         170       180
                  ....*....|....*....|....*..
gi 1972290045 199 SLFVPQGSTDRSMD---LNQSLPIRQS 222
Cdd:COG5063   324 GAFPSGGAVCKSFDkknLDFSVKALQR 350
CTH1 COG5063
CCCH-type Zn-finger protein [General function prediction only];
99-178 9.03e-06

CCCH-type Zn-finger protein [General function prediction only];


Pssm-ID: 227395 [Multi-domain]  Cd Length: 351  Bit Score: 46.20  E-value: 9.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972290045  99 FKTALCDAYKRSQACSYGDQCRFAHGVHELRLpmnprGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIH-KIVDGNAAKLA 177
Cdd:COG5063   113 YKTEMLRSSTEIPYCRYPDKNPFAHSKAISSL-----AQTHPKYKTESLEVFINPGYVPYSKRCCFISlPLTDINLQPLS 187


                  .
gi 1972290045 178 S 178
Cdd:COG5063   188 Q 188
ZnF_C3H1 smart00356
zinc finger;
99-124 1.15e-04

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 38.38  E-value: 1.15e-04
                           10        20
                   ....*....|....*....|....*.
gi 1972290045   99 FKTALCDAYKRSQaCSYGDQCRFAHG 124
Cdd:smart00356   2 YKTELCKFFKRGY-CPRGDRCKFAHP 26
COG5252 COG5252
Uncharacterized conserved protein, contains CCCH-type Zn-finger protein [General function ...
 61-171 4.59e-04

Uncharacterized conserved protein, contains CCCH-type Zn-finger protein [General function prediction only];


Pssm-ID: 227577 [Multi-domain]  Cd Length: 299  Bit Score: 40.84  E-value: 4.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972290045  61 QNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKED--------AFKTALCDAYKrSQACSYGDQCRFAHGVHELR--- 129
Cdd:COG5252    37 RSTKVQAIIKQIETLNLKEQLEKKEKMRMEEKRREPEkqviragvDPKTVVCALFL-NKTCAKGDACKFAHGKEEARkte 115

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1972290045 130 --------------LPMNPRGRNHPKyktVLCDKF-SMTGNCKYG---------TRCQFIHKIVDG 171
Cdd:COG5252   116 kpdlysdvrdkeedVPLGKRPWINTD---RVCKFFiEAMESGKYGwgwtcpngnMRCSYIHKLPDG 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH