NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2036579109|ref|NP_001381891|]
View 

acrosomal protein KIAA1210 isoform 1 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DUF4592 super family cl21119
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, ...
 193-280 1.17e-12

Domain of unknown function (DUF4592); This protein family is a domain of unknown function, which lies to the N-terminus of the protein. This domain family is found in eukaryotes, and is typically between 114 and 130 amino acids in length. There are two completely conserved residues (L and A) that may be functionally important. In humans, the gene that encodes this protein lies in the position, chromosome 2 open reading frame 55.


The actual alignment was detected with superfamily member pfam15262:

Pssm-ID: 464602 [Multi-domain]  Cd Length: 127  Bit Score: 66.29  E-value: 1.17e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2036579109  193 SLDDESPKNPQKKALPHKSLTAT--------------------QSFSELSSGPDCSQSLTAFatlaSTSSTQLPIGFSTP 252
Cdd:pfam15262   24 SEDDGLPRSPPEISLLHEILLSTeskssdppqhlsslslagtgSEEEEQSTPVKSSRPKSPF----SPSGTIEPINFDAP 99

                           90       100
                   ....*....|....*....|....*...
gi 2036579109  253 ATTQGCLDSSAARHKMTLNPRKQKKNLQ 280
Cdd:pfam15262  100 PQALACLDNSAAKHKLSVKPKNQRASRK 127
 
Name Accession Description Interval E-value
DUF4592 pfam15262
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, ...
 193-280 1.17e-12

Domain of unknown function (DUF4592); This protein family is a domain of unknown function, which lies to the N-terminus of the protein. This domain family is found in eukaryotes, and is typically between 114 and 130 amino acids in length. There are two completely conserved residues (L and A) that may be functionally important. In humans, the gene that encodes this protein lies in the position, chromosome 2 open reading frame 55.


Pssm-ID: 464602 [Multi-domain]  Cd Length: 127  Bit Score: 66.29  E-value: 1.17e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2036579109  193 SLDDESPKNPQKKALPHKSLTAT--------------------QSFSELSSGPDCSQSLTAFatlaSTSSTQLPIGFSTP 252
Cdd:pfam15262   24 SEDDGLPRSPPEISLLHEILLSTeskssdppqhlsslslagtgSEEEEQSTPVKSSRPKSPF----SPSGTIEPINFDAP 99

                           90       100
                   ....*....|....*....|....*...
gi 2036579109  253 ATTQGCLDSSAARHKMTLNPRKQKKNLQ 280
Cdd:pfam15262  100 PQALACLDNSAAKHKLSVKPKNQRASRK 127
 
Name Accession Description Interval E-value
DUF4592 pfam15262
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, ...
 193-280 1.17e-12

Domain of unknown function (DUF4592); This protein family is a domain of unknown function, which lies to the N-terminus of the protein. This domain family is found in eukaryotes, and is typically between 114 and 130 amino acids in length. There are two completely conserved residues (L and A) that may be functionally important. In humans, the gene that encodes this protein lies in the position, chromosome 2 open reading frame 55.


Pssm-ID: 464602 [Multi-domain]  Cd Length: 127  Bit Score: 66.29  E-value: 1.17e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2036579109  193 SLDDESPKNPQKKALPHKSLTAT--------------------QSFSELSSGPDCSQSLTAFatlaSTSSTQLPIGFSTP 252
Cdd:pfam15262   24 SEDDGLPRSPPEISLLHEILLSTeskssdppqhlsslslagtgSEEEEQSTPVKSSRPKSPF----SPSGTIEPINFDAP 99

                           90       100
                   ....*....|....*....|....*...
gi 2036579109  253 ATTQGCLDSSAARHKMTLNPRKQKKNLQ 280
Cdd:pfam15262  100 PQALACLDNSAAKHKLSVKPKNQRASRK 127
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH