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Conserved domains on  [gi|2173616011|ref|NP_001386287|]
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cip1-interacting zinc finger protein isoform 2 [Rattus norvegicus]

Protein Classification

ZnF_U1 and zf-C2H2_jaz domain-containing protein( domain architecture ID 10648578)

protein containing domains PHA03247, ZnF_U1, and zf-C2H2_jaz

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 93-399 2.13e-08

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 58.41  E-value: 2.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011   93 AMPPATYDSASLTMPTAALGNLRAYNVTAPNLAA--PSLTPPQMvtpnlqqffPQATRQSLLGPPPVGIPINPSQHNHSG 170
Cdd:PHA03247  2731 ASPALPAAPAPPAVPAGPATPGGPARPARPPTTAgpPAPAPPAA---------PAAGPPRRLTRPAVASLSESRESLPSP 2801

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  171 RNSQKQPRTPSSTTPNHKDSSSQTVPLDDREDPTEGSEEATELQMDTAEDQDSLVFPDG-LASEPQVHEPEPEPFEALEP 249
Cdd:PHA03247  2802 WDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGdVRRRPPSRSPAAKPAAPARP 2881

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  250 PAKRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDQLPEPPEALVVPRIQPQVlQIQTLSKLQKQAQTQTSPEHL 329
Cdd:PHA03247  2882 PVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRP-QPPLAPTTDPAGAGEPSGAVP 2960

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  330 APQQNQVSTQAQPQEQTSEKTQDQPQTWPQGSAPPPEQASVPAcatepqLLSNAAEVGRDpEETLPEPVS 399
Cdd:PHA03247  2961 QPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSR------VSSWASSLALH-EETDPPPVS 3023
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 575-599 1.72e-05

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


:

Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 42.16  E-value: 1.72e-05
                          10        20
                  ....*....|....*....|....*
gi 2173616011 575 FCTICNRYFKTPRKFVEHVKSQGHK 599
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 481-513 1.67e-04

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 39.54  E-value: 1.67e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2173616011  481 QFFCYICKASCSSQQEFQDHMSEAQHQQRLGEM 513
Cdd:smart00451   3 GFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 689-722 3.69e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 35.69  E-value: 3.69e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 2173616011  689 GYVCRICHKFYDSNSEFRlSHCKSLAHFENLQKY 722
Cdd:smart00451   3 GFYCKLCNVTFTDEISVE-AHLKGKKHKKNVKKR 35
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 93-399 2.13e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 58.41  E-value: 2.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011   93 AMPPATYDSASLTMPTAALGNLRAYNVTAPNLAA--PSLTPPQMvtpnlqqffPQATRQSLLGPPPVGIPINPSQHNHSG 170
Cdd:PHA03247  2731 ASPALPAAPAPPAVPAGPATPGGPARPARPPTTAgpPAPAPPAA---------PAAGPPRRLTRPAVASLSESRESLPSP 2801

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  171 RNSQKQPRTPSSTTPNHKDSSSQTVPLDDREDPTEGSEEATELQMDTAEDQDSLVFPDG-LASEPQVHEPEPEPFEALEP 249
Cdd:PHA03247  2802 WDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGdVRRRPPSRSPAAKPAAPARP 2881

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  250 PAKRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDQLPEPPEALVVPRIQPQVlQIQTLSKLQKQAQTQTSPEHL 329
Cdd:PHA03247  2882 PVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRP-QPPLAPTTDPAGAGEPSGAVP 2960

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  330 APQQNQVSTQAQPQEQTSEKTQDQPQTWPQGSAPPPEQASVPAcatepqLLSNAAEVGRDpEETLPEPVS 399
Cdd:PHA03247  2961 QPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSR------VSSWASSLALH-EETDPPPVS 3023
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 575-599 1.72e-05

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 42.16  E-value: 1.72e-05
                          10        20
                  ....*....|....*....|....*
gi 2173616011 575 FCTICNRYFKTPRKFVEHVKSQGHK 599
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 481-513 1.67e-04

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 39.54  E-value: 1.67e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2173616011  481 QFFCYICKASCSSQQEFQDHMSEAQHQQRLGEM 513
Cdd:smart00451   3 GFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
ftsN TIGR02223
cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a ...
 230-376 1.67e-04

cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a number of Proteobacteria. The N-terminal 30 residue region tends to by Lys/Arg-rich, and is followed by a membrane-spanning region. This is followed by an acidic low-complexity region of variable length and a well-conserved C-terminal domain of two tandem regions matched by pfam05036 (Sporulation related repeat), found in several cell division and sporulation proteins. The role of FtsN as a suppressor for other cell division mutations is poorly understood; it may involve cell wall hydrolysis. [Cellular processes, Cell division]


Pssm-ID: 274041 [Multi-domain]  Cd Length: 298  Bit Score: 44.30  E-value: 1.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011 230 LASEPQVHEPEPEPFEALEPpakRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDQ----LPEPPEALVVPRIQP 305
Cdd:TIGR02223  75 LPPKPEERWSYIEELEAREV---LINDPEEPSNGGGVEESAQLTAEQRQLLEQMQADMRAAekvlATAPSEQTVAVEARK 151

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2173616011 306 QVlqIQTLSKLQKQAQTQTSPEHLAPQQNQVSTQAQPQEQTSEKT-QDQPQTWPQGSAPPPEQASVPACATE 376
Cdd:TIGR02223 152 QT--AEKKPQKARTAEAQKTPVETEKIASKVKEAKQKQKALPKQTaETQSNSKPIETAPKADKADKTKPKPK 221
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 689-722 3.69e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 35.69  E-value: 3.69e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 2173616011  689 GYVCRICHKFYDSNSEFRlSHCKSLAHFENLQKY 722
Cdd:smart00451   3 GFYCKLCNVTFTDEISVE-AHLKGKKHKKNVKKR 35
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 481-507 4.00e-03

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 35.22  E-value: 4.00e-03
                          10        20
                  ....*....|....*....|....*..
gi 2173616011 481 QFFCYICKASCSSQQEFQDHMSEAQHQ 507
Cdd:pfam12171   1 QFYCVLCDKYFKSENALQNHLKSKKHK 27
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 93-399 2.13e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 58.41  E-value: 2.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011   93 AMPPATYDSASLTMPTAALGNLRAYNVTAPNLAA--PSLTPPQMvtpnlqqffPQATRQSLLGPPPVGIPINPSQHNHSG 170
Cdd:PHA03247  2731 ASPALPAAPAPPAVPAGPATPGGPARPARPPTTAgpPAPAPPAA---------PAAGPPRRLTRPAVASLSESRESLPSP 2801

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  171 RNSQKQPRTPSSTTPNHKDSSSQTVPLDDREDPTEGSEEATELQMDTAEDQDSLVFPDG-LASEPQVHEPEPEPFEALEP 249
Cdd:PHA03247  2802 WDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGdVRRRPPSRSPAAKPAAPARP 2881

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  250 PAKRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDQLPEPPEALVVPRIQPQVlQIQTLSKLQKQAQTQTSPEHL 329
Cdd:PHA03247  2882 PVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRP-QPPLAPTTDPAGAGEPSGAVP 2960

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  330 APQQNQVSTQAQPQEQTSEKTQDQPQTWPQGSAPPPEQASVPAcatepqLLSNAAEVGRDpEETLPEPVS 399
Cdd:PHA03247  2961 QPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSR------VSSWASSLALH-EETDPPPVS 3023
PHA03247 PHA03247
large tegument protein UL36; Provisional
 95-412 2.20e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 54.94  E-value: 2.20e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011   95 PPATYDSASLTMPTAALGNLRAYNVTAPNLAAPSLTPPQMVTPNlqqffPQATRQSLLGPPPVGIPINPSqhnhsgrnSQ 174
Cdd:PHA03247  2712 PHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPA-----RPARPPTTAGPPAPAPPAAPA--------AG 2778

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  175 KQPRTPSSTTPNHKDSSSQTVPLDDREDPTEGSEEATELQMDTAEDQDSLvfPDGLASEPQVHEPEPEPFEALEPPAKRL 254
Cdd:PHA03247  2779 PPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPL--PPPTSAQPTAPPPPPGPPPPSLPLGGSV 2856

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  255 RSSEESTEKGPTGQPQARvqPQTQMTAPKQTQTPDQLPEPPEALVVPRIQPQvlqiqtlsklqkqaqTQTSPEHLAPQQN 334
Cdd:PHA03247  2857 APGGDVRRRPPSRSPAAK--PAAPARPPVRRLARPAVSRSTESFALPPDQPE---------------RPPQPQAPPPPQP 2919

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2173616011  335 QVSTQAQPQEQTSEKTQDQPQtwpqgsaPPPEQASVPACATEPQLLSNAAEVGRDPEETLPEPVSAQSSEDRSQEPSA 412
Cdd:PHA03247  2920 QPQPPPPPQPQPPPPPPPRPQ-------PPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPA 2990
PRK10927 PRK10927
cell division protein FtsN;
239-406 9.96e-06

cell division protein FtsN;


Pssm-ID: 236797 [Multi-domain]  Cd Length: 319  Bit Score: 48.52  E-value: 9.96e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011 239 PEPEP----FEALEPPAKRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQT---QTPDQLPEPPEALVVPRIQPQVLQIQ 311
Cdd:PRK10927   77 PKPEErwryIKELESRQPGVRAPTEPSAGGEVKTPEQLTPEQRQLLEQMQAdmrQQPTQLVEVPWNEQTPEQRQQTLQRQ 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011 312 ----TLSKLQKQAQTQTSPEHLAPQQNQVSTQAQPQEQTSEKTQDQPQTwpqgsaPPPEQASVPACATEPQLLSNAAEVG 387
Cdd:PRK10927  157 rqaqQLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASTQQ------PYQDLLQTPAHTTAQSKPQQAAPVT 230

                         170
                  ....*....|....*....
gi 2173616011 388 RDPEEtlPEPVSAQSSEDR 406
Cdd:PRK10927  231 RAADA--PKPTAEKKDERR 247
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 575-599 1.72e-05

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 42.16  E-value: 1.72e-05
                          10        20
                  ....*....|....*....|....*
gi 2173616011 575 FCTICNRYFKTPRKFVEHVKSQGHK 599
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
PHA03247 PHA03247
large tegument protein UL36; Provisional
 109-480 1.32e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.70  E-value: 1.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  109 AALGNLRAYNVTAPNLAAPSLTPPQMVTPNLQQFFPQATRQSLLGPPPVGIPINPSQHNHSGRNSQKQPRTPSSTTPnhk 188
Cdd:PHA03247  2690 PTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGP--- 2766

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  189 dsSSQTVPlddrEDPTEGSEEATElqmdtaedqdslvfPDGLASEPQVHEPEPEPFEALEPPAKRLRSSEESTekgPTGQ 268
Cdd:PHA03247  2767 --PAPAPP----AAPAAGPPRRLT--------------RPAVASLSESRESLPSPWDPADPPAAVLAPAAALP---PAAS 2823

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  269 PQARVQPQT--QMTAPKQTQTPDQLPEPPEALVVPRiqpqvlqiqtlSKLQKQAQTQTSPEHLA-PQQNQVSTQAQPQEQ 345
Cdd:PHA03247  2824 PAGPLPPPTsaQPTAPPPPPGPPPPSLPLGGSVAPG-----------GDVRRRPPSRSPAAKPAaPARPPVRRLARPAVS 2892

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  346 TSekTQDQPQtwPQGSAPPPEQASVPACATEPQllsnaaevgrdPEETLPEPVSAQSSEDRSQEPSAGGLDVGECEKRAG 425
Cdd:PHA03247  2893 RS--TESFAL--PPDQPERPPQPQAPPPPQPQP-----------QPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSG 2957

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2173616011  426 EVLGMW-GAGSSLKVTILQSSNSRAFNTTPLTSGPRPGDSASATPALASTPSKQSL 480
Cdd:PHA03247  2958 AVPQPWlGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLAL 3013
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 230-404 1.52e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 45.24  E-value: 1.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011 230 LASEPQVHEPEPE-PFEALEPPAkrlrsseestEKGPTGQPQARVQPQTQMTAPKQ-TQTPDQLPEPPEALVVPRI---Q 304
Cdd:PRK07994  357 LAFHPAAPLPEPEvPPQSAAPAA----------SAQATAAPTAAVAPPQAPAVPPPpASAPQQAPAVPLPETTSQLlaaR 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011 305 PQVLQIQTLSKLQKQAQTQTSPEHLAPQQNQVSTQAQPQEQTSEKTQDQPQTWPQGSAPPPEQASVPacATEPQLLSNAA 384
Cdd:PRK07994  427 QQLQRAQGATKAKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEP--VATPKALKKAL 504

                         170       180
                  ....*....|....*....|
gi 2173616011 385 EVGRDPEetLPEPVSAQSSE 404
Cdd:PRK07994  505 EHEKTPE--LAAKLAAEAIE 522
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 481-513 1.67e-04

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 39.54  E-value: 1.67e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2173616011  481 QFFCYICKASCSSQQEFQDHMSEAQHQQRLGEM 513
Cdd:smart00451   3 GFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
ftsN TIGR02223
cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a ...
 230-376 1.67e-04

cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a number of Proteobacteria. The N-terminal 30 residue region tends to by Lys/Arg-rich, and is followed by a membrane-spanning region. This is followed by an acidic low-complexity region of variable length and a well-conserved C-terminal domain of two tandem regions matched by pfam05036 (Sporulation related repeat), found in several cell division and sporulation proteins. The role of FtsN as a suppressor for other cell division mutations is poorly understood; it may involve cell wall hydrolysis. [Cellular processes, Cell division]


Pssm-ID: 274041 [Multi-domain]  Cd Length: 298  Bit Score: 44.30  E-value: 1.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011 230 LASEPQVHEPEPEPFEALEPpakRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDQ----LPEPPEALVVPRIQP 305
Cdd:TIGR02223  75 LPPKPEERWSYIEELEAREV---LINDPEEPSNGGGVEESAQLTAEQRQLLEQMQADMRAAekvlATAPSEQTVAVEARK 151

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2173616011 306 QVlqIQTLSKLQKQAQTQTSPEHLAPQQNQVSTQAQPQEQTSEKT-QDQPQTWPQGSAPPPEQASVPACATE 376
Cdd:TIGR02223 152 QT--AEKKPQKARTAEAQKTPVETEKIASKVKEAKQKQKALPKQTaETQSNSKPIETAPKADKADKTKPKPK 221
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 287-411 2.45e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 44.69  E-value: 2.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  287 TPDQLPEP-PEALVVPRIQPQVLQiQTLSKLQKQAQTQTSpehLAPQQNQVSTQaQPQEQTSEKTQDQPQTWPQGSAPPP 365
Cdd:PRK10263   746 TPIVEPVQqPQQPVAPQQQYQQPQ-QPVAPQPQYQQPQQP---VAPQPQYQQPQ-QPVAPQPQYQQPQQPVAPQPQYQQP 820

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 2173616011  366 EQASVPacatEPQLLSNAAEVGRDPEETLPEPVSAQSSEDRS-QEPS 411
Cdd:PRK10263   821 QQPVAP----QPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPlHKPT 863
PRK12757 PRK12757
cell division protein FtsN; Provisional
 265-365 4.04e-04

cell division protein FtsN; Provisional


Pssm-ID: 237191 [Multi-domain]  Cd Length: 256  Bit Score: 42.72  E-value: 4.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011 265 PTGQPQARVQPQ---------TQMTAPKQtQTPDQLPEPPEALVVPRIQPQVLQIQTLSKLQKQAQTQTSPEHLAPQQnq 335
Cdd:PRK12757   68 PSAGGEVNSPTQltdeqrqllEQMQADMR-QQPTQLSEVPYNEQTPQVPRSTVQIQQQAQQQQPPATTAQPQPVTPPR-- 144

                          90       100       110
                  ....*....|....*....|....*....|
gi 2173616011 336 vsTQAQPQEQTSEKTQDQPQTWPQGSAPPP 365
Cdd:PRK12757  145 --QTTAPVQPQTPAPVRTQPAAPVTQAVEA 172
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 268-377 5.78e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 43.54  E-value: 5.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  268 QPQARVQPQTQMTAPKQTQTPDQLPEPPEALVVPriQPQVLQIQTLSKLQKQAQTQTSPEHLAPQQNQVSTQAQPQEQTS 347
Cdd:PRK10263   767 QPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAP--QPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDT 844

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 2173616011  348 -------EKTQDQPQTWPQGSAPPPEQASVPACATEP 377
Cdd:PRK10263   845 llhpllmRNGDSRPLHKPTTPLPSLDLLTPPPSEVEP 881
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
 163-363 1.07e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 42.79  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011 163 PSQHNHSGRNSQKQPRTPSSTTPNHKDSSSQTVP-----LDDREDPTEGSEEATELQMDTAEDQDSlvfpDGLASEPQVH 237
Cdd:PRK14949  569 DDEQHSANVQSAQSAAEAQPSSQSLSPISAVTTAaaslaDDDILDAVLAARDSLLSDLDALSPKEG----DGKKSSADRK 644

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011 238 E--------PEPEPFEALEPPAKRLRSSEESTEKGPT----GQPQARVQPQTQMTAPKQTQTPDQLP--EPPEALVVPRI 303
Cdd:PRK14949  645 PktppsrapPASLSKPASSPDASQTSASFDLDPDFELathqSVPEAALASGSAPAPPPVPDPYDRPPweEAPEVASANDG 724

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011 304 QPQVLQIQTLSKLQKQAQTQTSPEHLAPQQnQVSTQAQPQEQTSEKTQDQPQTWPQGSAP 363
Cdd:PRK14949  725 PNNAAEGNLSESVEDASNSELQAVEQQATH-QPQVQAEAQSPASTTALTQTSSEVQDTEL 783
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 234-366 2.05e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.99  E-value: 2.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  234 PQVHEPEPEPFEALE--PPAKRLRSSEESTEKgPTGQPQARVQPQTQMTAPKQTQTPDQLPEPPEALVVPRIQPQVLQIQ 311
Cdd:PRK10263   364 PGPQTGEPVIAPAPEgyPQQSQYAQPAVQYNE-PLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPV 442

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2173616011  312 TLSKLQKQAQTQtspeHLAPQQNQVSTQAQPQEQTSEKTQDQPQTWPQGSAPPPE 366
Cdd:PRK10263   443 AGNAWQAEEQQS----TFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPE 493
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 689-722 3.69e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 35.69  E-value: 3.69e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 2173616011  689 GYVCRICHKFYDSNSEFRlSHCKSLAHFENLQKY 722
Cdd:smart00451   3 GFYCKLCNVTFTDEISVE-AHLKGKKHKKNVKKR 35
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 218-408 3.86e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 40.84  E-value: 3.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  218 AEDQDSLVFPDGLASEPQVHEPEP--------EPFEALEPPAKRLRSSEESTEkgPTGQPQARVQPQTQMTAPKQTQTPD 289
Cdd:PRK10263   286 AADPDDVLFSGNRATQPEYDEYDPllngapitEPVAVAAAATTATQSWAAPVE--PVTQTPPVASVDVPPAQPTVAWQPV 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011  290 QLPEPPEALVVPRI-----QPQVLQIQTLSKLQKQAQTQTSPEHLAPQQNQVStQAQPQEQTSEKTQDQPQTWPQGSAPP 364
Cdd:PRK10263   364 PGPQTGEPVIAPAPegypqQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPA-QQPYYAPAPEQPAQQPYYAPAPEQPV 442

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 2173616011  365 PEQASVPacatEPQLLSNAAEVGRDPEETLPEPVSAQSSEDRSQ 408
Cdd:PRK10263   443 AGNAWQA----EEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQ 482
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 481-507 4.00e-03

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 35.22  E-value: 4.00e-03
                          10        20
                  ....*....|....*....|....*..
gi 2173616011 481 QFFCYICKASCSSQQEFQDHMSEAQHQ 507
Cdd:pfam12171   1 QFYCVLCDKYFKSENALQNHLKSKKHK 27
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 227-417 6.42e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.97  E-value: 6.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011 227 PDGLASEPQVHEPEPEPFEALEPPAKRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDQLPEPPEALVVPRIQPQ 306
Cdd:PRK07764  629 PAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAAT 708

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2173616011 307 vlqiqtlsklqKQAQTQTSPEHLAPQQNQVSTQAQPQEQTSEKTQDQPQTWPQGSAPPPEQASVPACATEPQLLSNAAEV 386
Cdd:PRK07764  709 -----------PPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPS 777

                         170       180       190
                  ....*....|....*....|....*....|..
gi 2173616011 387 GRD-PEETLPEPVSAQSSEDRsQEPSAGGLDV 417
Cdd:PRK07764  778 PPSeEEEMAEDDAPSMDDEDR-RDAEEVAMEL 808
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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