|
Name |
Accession |
Description |
Interval |
E-value |
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
49-139 |
2.93e-24 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
:
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 99.79 E-value: 2.93e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 49 GNYSVNGNCEWLIEAPsPQHRILLDFLFLDTE----CTYDYLFVYDGDSPRGPLLASLSGSTRPPPIEASSGKMLLHLFS 124
Cdd:cd00041 20 NNYPNNLNCVWTIEAP-PGYRIRLTFEDFDLEsspnCSYDYLEIYDGPSTSSPLLGRFCGSTLPPPIISSGNSLTVRFRS 98
|
90
....*....|....*
gi 145701025 125 DANYNLLGFNASFRF 139
Cdd:cd00041 99 DSSVTGRGFKATYSA 113
|
|
| NanM |
COG3055 |
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis]; |
227-531 |
1.99e-22 |
|
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
:
Pssm-ID: 442289 [Multi-domain] Cd Length: 277 Bit Score: 99.85 E-value: 1.99e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 227 ARIGAAGAFLSppGLLAVFGGQDLNNALGDLVLYNFSANTWESwdLSPAP-AARHSHVAVAWAGSLVLMGG---ELADGS 302
Cdd:COG3055 12 PRSEAAAALLD--GKVYVAGGLSGGSASNSFEVYDPATNTWSE--LAPLPgPPRHHAAAVAQDGKLYVFGGftgANPSST 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 303 LTNDVWAFSPlGRGHWELLAPPASSSsgppglaGHAAALVDDVWLYVSGGRtpHDLFSSGLFrFRLDSTSGGyWEQVIPA 382
Cdd:COG3055 88 PLNDVYVYDP-ATNTWTKLAPMPTPR-------GGATALLLDGKIYVVGGW--DDGGNVAWV-EVYDPATGT-WTQLAPL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 383 ggrPPAATGHSMVFhAPSRALLVHGGhrpstARFSVRVNStelfhvdrhvWTTLKgrdglQGPRERAFHTASVLGNYMVV 462
Cdd:COG3055 156 ---PTPRDHLAAAV-LPDGKILVIGG-----RNGSGFSNT----------WTTLA-----PLPTARAGHAAAVLGGKILV 211
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 145701025 463 YGGNVHTHyqeekcyeDGIFFYHLGCHQWVSGAELappgtpegraapPSGRYSHVAAVLGGSVLLVAGG 531
Cdd:COG3055 212 FGGESGFS--------DEVEAYDPATNTWTALGEL------------PTPRHGHAAVLTDGKVYVIGGE 260
|
|
| NanM |
COG3055 |
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis]; |
1490-1791 |
9.62e-21 |
|
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
:
Pssm-ID: 442289 [Multi-domain] Cd Length: 277 Bit Score: 94.84 E-value: 9.62e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 1490 EDGGPGPSPRSfHAAAYVPAGRgaMYLLGGLTAGGVTRDFWVLNLTTLQWrQEKAPqtveLPAVA-GHTLTARRGLSLLL 1568
Cdd:COG3055 4 SSLPDLPTPRS-EAAAALLDGK--VYVAGGLSGGSASNSFEVYDPATNTW-SELAP----LPGPPrHHAAAVAQDGKLYV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 1569 VGGYSPENGFNQQL---LEYQLATGTWVSGAqsgTPPTGLYGHSAVYHEatDSLYVFGGFRFHVELAapSPELYSLhcPD 1645
Cdd:COG3055 76 FGGFTGANPSSTPLndvYVYDPATNTWTKLA---PMPTPRGGATALLLD--GKIYVVGGWDDGGNVA--WVEVYDP--AT 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 1646 RTWSLLAPSQGAKRDRMRNVRGSSRGLgqVPGeqpGSWGFREVRKkmalWAALAgtggfleeisPHlkePRPRLFHASAL 1725
Cdd:COG3055 147 GTWTQLAPLPTPRDHLAAAVLPDGKIL--VIG---GRNGSGFSNT----WTTLA----------PL---PTARAGHAAAV 204
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 145701025 1726 LGDTMVVLGGRSDpdeFSSDVLLYQVNCNAWllpdltrsaSVGPPMEESV-AHAVAAVGSRLYISGG 1791
Cdd:COG3055 205 LGGKILVFGGESG---FSDEVEAYDPATNTW---------TALGELPTPRhGHAAVLTDGKVYVIGG 259
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1143-1192 |
2.64e-11 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
:
Pssm-ID: 238012 Cd Length: 50 Bit Score: 60.83 E-value: 2.64e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 145701025 1143 PCQCNGHGDpRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSC 1192
Cdd:cd00055 1 PCDCNGHGS-LSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGGGC 49
|
|
| EGF_3 |
pfam12947 |
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ... |
1011-1045 |
1.86e-06 |
|
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.
:
Pssm-ID: 463759 [Multi-domain] Cd Length: 36 Bit Score: 46.44 E-value: 1.86e-06
10 20 30
....*....|....*....|....*....|....*
gi 145701025 1011 CRLGLARCHPRATCLNTPLSYECHCQRGYQGDGIS 1045
Cdd:pfam12947 1 CSDNNGGCHPNATCTNTGGSFTCTCNDGYTGDGVT 35
|
|
| PSI |
pfam01437 |
Plexin repeat; A cysteine rich repeat found in several different extracellular receptors. The ... |
883-931 |
3.23e-03 |
|
Plexin repeat; A cysteine rich repeat found in several different extracellular receptors. The function of the repeat is unknown. Three copies of the repeat are found Plexin. Two copies of the repeat are found in mahogany protein. A related C. elegans protein contains four copies of the repeat. The Met receptor contains a single copy of the repeat. The Pfam alignment shows 6 conserved cysteine residues that may form three conserved disulphide bridges, whereas some members show 8 conserved cysteines. The pattern of conservation suggests that cysteines 5 and 7 (that are not absolutely conserved) form a disulphide bridge (Personal observation. A Bateman).
:
Pssm-ID: 396154 [Multi-domain] Cd Length: 52 Bit Score: 38.07 E-value: 3.23e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 145701025 883 CSQRLTCEDCL-ANSSQCAWCQSTHTCFLFAAYlaRYPHGGCRGWDDSVH 931
Cdd:pfam01437 2 CSQYTSCSSCLaARDPYCGWCSSEGRCVRRSAC--GAPEGNCEEWEQASS 49
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
49-139 |
2.93e-24 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 99.79 E-value: 2.93e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 49 GNYSVNGNCEWLIEAPsPQHRILLDFLFLDTE----CTYDYLFVYDGDSPRGPLLASLSGSTRPPPIEASSGKMLLHLFS 124
Cdd:cd00041 20 NNYPNNLNCVWTIEAP-PGYRIRLTFEDFDLEsspnCSYDYLEIYDGPSTSSPLLGRFCGSTLPPPIISSGNSLTVRFRS 98
|
90
....*....|....*
gi 145701025 125 DANYNLLGFNASFRF 139
Cdd:cd00041 99 DSSVTGRGFKATYSA 113
|
|
| NanM |
COG3055 |
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis]; |
227-531 |
1.99e-22 |
|
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442289 [Multi-domain] Cd Length: 277 Bit Score: 99.85 E-value: 1.99e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 227 ARIGAAGAFLSppGLLAVFGGQDLNNALGDLVLYNFSANTWESwdLSPAP-AARHSHVAVAWAGSLVLMGG---ELADGS 302
Cdd:COG3055 12 PRSEAAAALLD--GKVYVAGGLSGGSASNSFEVYDPATNTWSE--LAPLPgPPRHHAAAVAQDGKLYVFGGftgANPSST 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 303 LTNDVWAFSPlGRGHWELLAPPASSSsgppglaGHAAALVDDVWLYVSGGRtpHDLFSSGLFrFRLDSTSGGyWEQVIPA 382
Cdd:COG3055 88 PLNDVYVYDP-ATNTWTKLAPMPTPR-------GGATALLLDGKIYVVGGW--DDGGNVAWV-EVYDPATGT-WTQLAPL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 383 ggrPPAATGHSMVFhAPSRALLVHGGhrpstARFSVRVNStelfhvdrhvWTTLKgrdglQGPRERAFHTASVLGNYMVV 462
Cdd:COG3055 156 ---PTPRDHLAAAV-LPDGKILVIGG-----RNGSGFSNT----------WTTLA-----PLPTARAGHAAAVLGGKILV 211
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 145701025 463 YGGNVHTHyqeekcyeDGIFFYHLGCHQWVSGAELappgtpegraapPSGRYSHVAAVLGGSVLLVAGG 531
Cdd:COG3055 212 FGGESGFS--------DEVEAYDPATNTWTALGEL------------PTPRHGHAAVLTDGKVYVIGGE 260
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
49-137 |
9.19e-22 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 92.07 E-value: 9.19e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 49 GNYSVNGNCEWLIEAPsPQHRILLDFLFLDTE----CTYDYLFVYDGDSPRGPLLASLSGSTRPPPIEASSG-KMLLHLF 123
Cdd:smart00042 10 QSYPNNLDCVWTIRAP-PGYRIELQFTDFDLEssdnCEYDYVEIYDGPSASSPLLGRFCGSEAPPPVISSSSnSLTLTFV 88
|
90
....*....|....
gi 145701025 124 SDANYNLLGFNASF 137
Cdd:smart00042 89 SDSSVQKRGFSARY 102
|
|
| NanM |
COG3055 |
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis]; |
1490-1791 |
9.62e-21 |
|
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442289 [Multi-domain] Cd Length: 277 Bit Score: 94.84 E-value: 9.62e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 1490 EDGGPGPSPRSfHAAAYVPAGRgaMYLLGGLTAGGVTRDFWVLNLTTLQWrQEKAPqtveLPAVA-GHTLTARRGLSLLL 1568
Cdd:COG3055 4 SSLPDLPTPRS-EAAAALLDGK--VYVAGGLSGGSASNSFEVYDPATNTW-SELAP----LPGPPrHHAAAVAQDGKLYV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 1569 VGGYSPENGFNQQL---LEYQLATGTWVSGAqsgTPPTGLYGHSAVYHEatDSLYVFGGFRFHVELAapSPELYSLhcPD 1645
Cdd:COG3055 76 FGGFTGANPSSTPLndvYVYDPATNTWTKLA---PMPTPRGGATALLLD--GKIYVVGGWDDGGNVA--WVEVYDP--AT 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 1646 RTWSLLAPSQGAKRDRMRNVRGSSRGLgqVPGeqpGSWGFREVRKkmalWAALAgtggfleeisPHlkePRPRLFHASAL 1725
Cdd:COG3055 147 GTWTQLAPLPTPRDHLAAAVLPDGKIL--VIG---GRNGSGFSNT----WTTLA----------PL---PTARAGHAAAV 204
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 145701025 1726 LGDTMVVLGGRSDpdeFSSDVLLYQVNCNAWllpdltrsaSVGPPMEESV-AHAVAAVGSRLYISGG 1791
Cdd:COG3055 205 LGGKILVFGGESG---FSDEVEAYDPATNTW---------TALGELPTPRhGHAAVLTDGKVYVIGG 259
|
|
| CUB |
pfam00431 |
CUB domain; |
30-137 |
3.96e-20 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 87.74 E-value: 3.96e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 30 CKGqrqVLREAPG--FVTDGAGNYSVNGNCEWLIEAPsPQHRILLDFLFLDTE----CTYDYLFVYDGDSPRGPLLASLS 103
Cdd:pfam00431 1 CGG---VLTDSSGsiSSPNYPNPYPPNKDCVWLIRAP-PGFRVKLTFQDFELEdhdeCGYDYVEIRDGPSASSPLLGRFC 76
|
90 100 110
....*....|....*....|....*....|....
gi 145701025 104 GSTRPPPIEASSGKMLLHLFSDANYNLLGFNASF 137
Cdd:pfam00431 77 GSGIPEDIVSSSNQMTIKFVSDASVQKRGFKATY 110
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1143-1192 |
2.64e-11 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 60.83 E-value: 2.64e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 145701025 1143 PCQCNGHGDpRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSC 1192
Cdd:cd00055 1 PCDCNGHGS-LSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGGGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1144-1192 |
6.27e-09 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 53.90 E-value: 6.27e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 145701025 1144 CQCNGHGDPRrGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRA-GGSC 1192
Cdd:pfam00053 1 CDCNPHGSLS-DTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDpPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1144-1189 |
1.85e-06 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 46.92 E-value: 1.85e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 145701025 1144 CQCNGHGDpRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAG 1189
Cdd:smart00180 1 CDCDPGGS-ASGTCDPDTGQCECKPNVTGRRCDRCAPGYYGDGPPG 45
|
|
| EGF_3 |
pfam12947 |
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ... |
1011-1045 |
1.86e-06 |
|
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.
Pssm-ID: 463759 [Multi-domain] Cd Length: 36 Bit Score: 46.44 E-value: 1.86e-06
10 20 30
....*....|....*....|....*....|....*
gi 145701025 1011 CRLGLARCHPRATCLNTPLSYECHCQRGYQGDGIS 1045
Cdd:pfam12947 1 CSDNNGGCHPNATCTNTGGSFTCTCNDGYTGDGVT 35
|
|
| EGF_CA |
smart00179 |
Calcium-binding EGF-like domain; |
1007-1040 |
1.00e-04 |
|
Calcium-binding EGF-like domain;
Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 41.85 E-value: 1.00e-04
10 20 30
....*....|....*....|....*....|....
gi 145701025 1007 DVDECRLGlARCHPRATCLNTPLSYECHCQRGYQ 1040
Cdd:smart00179 1 DIDECASG-NPCQNGGTCVNTVGSYRCECPPGYT 33
|
|
| Kelch_3 |
pfam13415 |
Galactose oxidase, central domain; |
1566-1613 |
1.18e-04 |
|
Galactose oxidase, central domain;
Pssm-ID: 433188 [Multi-domain] Cd Length: 49 Bit Score: 41.89 E-value: 1.18e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 145701025 1566 LLLVGGYSPENG-FNQQLLEYQLATGTWvsgAQSGTPPTGLYGHSAVYH 1613
Cdd:pfam13415 4 LYIFGGLGFDGQtRLNDLYVYDLDTNTW---TQIGDLPPPRSGHSATYI 49
|
|
| EGF_CA |
cd00054 |
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1007-1042 |
1.71e-04 |
|
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.
Pssm-ID: 238011 Cd Length: 38 Bit Score: 41.08 E-value: 1.71e-04
10 20 30
....*....|....*....|....*....|....*.
gi 145701025 1007 DVDECRLGlARCHPRATCLNTPLSYECHCQRGYQGD 1042
Cdd:cd00054 1 DIDECASG-NPCQNGGTCVNTVGSYRCSCPPGYTGR 35
|
|
| PLN02153 |
PLN02153 |
epithiospecifier protein |
1713-1791 |
8.79e-04 |
|
epithiospecifier protein
Pssm-ID: 177814 [Multi-domain] Cd Length: 341 Bit Score: 44.21 E-value: 8.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 1713 KEPRPRLFHASALLGDTMVVLGGRSDPDE-FSSDVLLYQVNCNAWLLPdltrSASVGPPMEESVAHAVAAVGSRLYISGG 1791
Cdd:PLN02153 18 KGPGPRCSHGIAVVGDKLYSFGGELKPNEhIDKDLYVFDFNTHTWSIA----PANGDVPRISCLGVRMVAVGTKLYIFGG 93
|
|
| Kelch_4 |
pfam13418 |
Galactose oxidase, central domain; |
227-276 |
9.44e-04 |
|
Galactose oxidase, central domain;
Pssm-ID: 433191 [Multi-domain] Cd Length: 49 Bit Score: 39.13 E-value: 9.44e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 145701025 227 ARIGAAgAFLSPPGLLAVFGGQDLNN-ALGDLVLYNFSANTWESwdLSPAP 276
Cdd:pfam13418 1 PRAYHT-STSIPDDTIYLFGGEGEDGtLLSDLWVFDLSTNEWTR--LGSLP 48
|
|
| PSI |
pfam01437 |
Plexin repeat; A cysteine rich repeat found in several different extracellular receptors. The ... |
883-931 |
3.23e-03 |
|
Plexin repeat; A cysteine rich repeat found in several different extracellular receptors. The function of the repeat is unknown. Three copies of the repeat are found Plexin. Two copies of the repeat are found in mahogany protein. A related C. elegans protein contains four copies of the repeat. The Met receptor contains a single copy of the repeat. The Pfam alignment shows 6 conserved cysteine residues that may form three conserved disulphide bridges, whereas some members show 8 conserved cysteines. The pattern of conservation suggests that cysteines 5 and 7 (that are not absolutely conserved) form a disulphide bridge (Personal observation. A Bateman).
Pssm-ID: 396154 [Multi-domain] Cd Length: 52 Bit Score: 38.07 E-value: 3.23e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 145701025 883 CSQRLTCEDCL-ANSSQCAWCQSTHTCFLFAAYlaRYPHGGCRGWDDSVH 931
Cdd:pfam01437 2 CSQYTSCSSCLaARDPYCGWCSSEGRCVRRSAC--GAPEGNCEEWEQASS 49
|
|
| PLN02153 |
PLN02153 |
epithiospecifier protein |
337-465 |
6.06e-03 |
|
epithiospecifier protein
Pssm-ID: 177814 [Multi-domain] Cd Length: 341 Bit Score: 41.51 E-value: 6.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 337 HAAALVDDVwLYVSGGR-TPHDLFSSGLFRFRLDSTSggyWeQVIPAGGRPPAATGHSMVFHAPSRALLVHGGhRPSTAR 415
Cdd:PLN02153 26 HGIAVVGDK-LYSFGGElKPNEHIDKDLYVFDFNTHT---W-SIAPANGDVPRISCLGVRMVAVGTKLYIFGG-RDEKRE 99
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 145701025 416 FSvrvnstELFHVD--RHVWTTLKGRDGLQGPRERAFHTASVLGNYMVVYGG 465
Cdd:PLN02153 100 FS------DFYSYDtvKNEWTFLTKLDEEGGPEARTFHSMASDENHVYVFGG 145
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
49-139 |
2.93e-24 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 99.79 E-value: 2.93e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 49 GNYSVNGNCEWLIEAPsPQHRILLDFLFLDTE----CTYDYLFVYDGDSPRGPLLASLSGSTRPPPIEASSGKMLLHLFS 124
Cdd:cd00041 20 NNYPNNLNCVWTIEAP-PGYRIRLTFEDFDLEsspnCSYDYLEIYDGPSTSSPLLGRFCGSTLPPPIISSGNSLTVRFRS 98
|
90
....*....|....*
gi 145701025 125 DANYNLLGFNASFRF 139
Cdd:cd00041 99 DSSVTGRGFKATYSA 113
|
|
| NanM |
COG3055 |
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis]; |
227-531 |
1.99e-22 |
|
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442289 [Multi-domain] Cd Length: 277 Bit Score: 99.85 E-value: 1.99e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 227 ARIGAAGAFLSppGLLAVFGGQDLNNALGDLVLYNFSANTWESwdLSPAP-AARHSHVAVAWAGSLVLMGG---ELADGS 302
Cdd:COG3055 12 PRSEAAAALLD--GKVYVAGGLSGGSASNSFEVYDPATNTWSE--LAPLPgPPRHHAAAVAQDGKLYVFGGftgANPSST 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 303 LTNDVWAFSPlGRGHWELLAPPASSSsgppglaGHAAALVDDVWLYVSGGRtpHDLFSSGLFrFRLDSTSGGyWEQVIPA 382
Cdd:COG3055 88 PLNDVYVYDP-ATNTWTKLAPMPTPR-------GGATALLLDGKIYVVGGW--DDGGNVAWV-EVYDPATGT-WTQLAPL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 383 ggrPPAATGHSMVFhAPSRALLVHGGhrpstARFSVRVNStelfhvdrhvWTTLKgrdglQGPRERAFHTASVLGNYMVV 462
Cdd:COG3055 156 ---PTPRDHLAAAV-LPDGKILVIGG-----RNGSGFSNT----------WTTLA-----PLPTARAGHAAAVLGGKILV 211
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 145701025 463 YGGNVHTHyqeekcyeDGIFFYHLGCHQWVSGAELappgtpegraapPSGRYSHVAAVLGGSVLLVAGG 531
Cdd:COG3055 212 FGGESGFS--------DEVEAYDPATNTWTALGEL------------PTPRHGHAAVLTDGKVYVIGGE 260
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
49-137 |
9.19e-22 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 92.07 E-value: 9.19e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 49 GNYSVNGNCEWLIEAPsPQHRILLDFLFLDTE----CTYDYLFVYDGDSPRGPLLASLSGSTRPPPIEASSG-KMLLHLF 123
Cdd:smart00042 10 QSYPNNLDCVWTIRAP-PGYRIELQFTDFDLEssdnCEYDYVEIYDGPSASSPLLGRFCGSEAPPPVISSSSnSLTLTFV 88
|
90
....*....|....
gi 145701025 124 SDANYNLLGFNASF 137
Cdd:smart00042 89 SDSSVQKRGFSARY 102
|
|
| NanM |
COG3055 |
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis]; |
1490-1791 |
9.62e-21 |
|
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442289 [Multi-domain] Cd Length: 277 Bit Score: 94.84 E-value: 9.62e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 1490 EDGGPGPSPRSfHAAAYVPAGRgaMYLLGGLTAGGVTRDFWVLNLTTLQWrQEKAPqtveLPAVA-GHTLTARRGLSLLL 1568
Cdd:COG3055 4 SSLPDLPTPRS-EAAAALLDGK--VYVAGGLSGGSASNSFEVYDPATNTW-SELAP----LPGPPrHHAAAVAQDGKLYV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 1569 VGGYSPENGFNQQL---LEYQLATGTWVSGAqsgTPPTGLYGHSAVYHEatDSLYVFGGFRFHVELAapSPELYSLhcPD 1645
Cdd:COG3055 76 FGGFTGANPSSTPLndvYVYDPATNTWTKLA---PMPTPRGGATALLLD--GKIYVVGGWDDGGNVA--WVEVYDP--AT 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 1646 RTWSLLAPSQGAKRDRMRNVRGSSRGLgqVPGeqpGSWGFREVRKkmalWAALAgtggfleeisPHlkePRPRLFHASAL 1725
Cdd:COG3055 147 GTWTQLAPLPTPRDHLAAAVLPDGKIL--VIG---GRNGSGFSNT----WTTLA----------PL---PTARAGHAAAV 204
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 145701025 1726 LGDTMVVLGGRSDpdeFSSDVLLYQVNCNAWllpdltrsaSVGPPMEESV-AHAVAAVGSRLYISGG 1791
Cdd:COG3055 205 LGGKILVFGGESG---FSDEVEAYDPATNTW---------TALGELPTPRhGHAAVLTDGKVYVIGG 259
|
|
| CUB |
pfam00431 |
CUB domain; |
30-137 |
3.96e-20 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 87.74 E-value: 3.96e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 30 CKGqrqVLREAPG--FVTDGAGNYSVNGNCEWLIEAPsPQHRILLDFLFLDTE----CTYDYLFVYDGDSPRGPLLASLS 103
Cdd:pfam00431 1 CGG---VLTDSSGsiSSPNYPNPYPPNKDCVWLIRAP-PGFRVKLTFQDFELEdhdeCGYDYVEIRDGPSASSPLLGRFC 76
|
90 100 110
....*....|....*....|....*....|....
gi 145701025 104 GSTRPPPIEASSGKMLLHLFSDANYNLLGFNASF 137
Cdd:pfam00431 77 GSGIPEDIVSSSNQMTIKFVSDASVQKRGFKATY 110
|
|
| NanM |
COG3055 |
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis]; |
1473-1624 |
6.34e-14 |
|
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442289 [Multi-domain] Cd Length: 277 Bit Score: 74.81 E-value: 6.34e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 1473 YRYSVSERRWTQMlagaedgGPGPSPRSFHAAAyVPAGRGamYLLGGLTAGGVTRDFWVLNLTTLQWRQeKAPQTVELPA 1552
Cdd:COG3055 93 YVYDPATNTWTKL-------APMPTPRGGATAL-LLDGKI--YVVGGWDDGGNVAWVEVYDPATGTWTQ-LAPLPTPRDH 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 1553 VAGHTL---------------------------TARRGLS-------LLLVGGyspENGFNQQLLEYQLATGTWVsgaQS 1598
Cdd:COG3055 162 LAAAVLpdgkilviggrngsgfsntwttlaplpTARAGHAaavlggkILVFGG---ESGFSDEVEAYDPATNTWT---AL 235
|
170 180
....*....|....*....|....*.
gi 145701025 1599 GTPPTGLYGHSAVYHEatDSLYVFGG 1624
Cdd:COG3055 236 GELPTPRHGHAAVLTD--GKVYVIGG 259
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1143-1192 |
2.64e-11 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 60.83 E-value: 2.64e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 145701025 1143 PCQCNGHGDpRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSC 1192
Cdd:cd00055 1 PCDCNGHGS-LSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGGGC 49
|
|
| NanM |
COG3055 |
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis]; |
211-313 |
1.59e-09 |
|
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442289 [Multi-domain] Cd Length: 277 Bit Score: 61.71 E-value: 1.59e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 211 GAGWWHNVSARDPAFSARIGAAGAFLSppGLLAVFGGQdlNNALGDLVLYNFSANTWESwdLSPAPAARHSHVAVAWAGS 290
Cdd:COG3055 180 GSGFSNTWTTLAPLPTARAGHAAAVLG--GKILVFGGE--SGFSDEVEAYDPATNTWTA--LGELPTPRHGHAAVLTDGK 253
|
90 100
....*....|....*....|...
gi 145701025 291 LVLMGGELADGSLTNDVWAFSPL 313
Cdd:COG3055 254 VYVIGGETKPGVRTPLVTSAEVY 276
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1144-1192 |
6.27e-09 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 53.90 E-value: 6.27e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 145701025 1144 CQCNGHGDPRrGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRA-GGSC 1192
Cdd:pfam00053 1 CDCNPHGSLS-DTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDpPQGC 49
|
|
| NanM |
COG3055 |
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis]; |
223-426 |
1.32e-08 |
|
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442289 [Multi-domain] Cd Length: 277 Bit Score: 58.63 E-value: 1.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 223 PAFSARIGAAGAFLsPPGLLAVFGGQDLNNALGDLVLYNFSANTWESwdLSPAPAARHSH-VAVAWAGSLVLMGGelADG 301
Cdd:COG3055 106 APMPTPRGGATALL-LDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQ--LAPLPTPRDHLaAAVLPDGKILVIGG--RNG 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 302 SLTNDVW---AFSPLGRghwellappassssgppglAGHAAALVDDVwLYVSGGRTPhdlFSSGLFRFrlDSTSGGyWEQ 378
Cdd:COG3055 181 SGFSNTWttlAPLPTAR-------------------AGHAAAVLGGK-ILVFGGESG---FSDEVEAY--DPATNT-WTA 234
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 145701025 379 V--IPAGGRPPAATGHSmvfhapSRALLVHGGHRPSTArfSVRVNSTELF 426
Cdd:COG3055 235 LgeLPTPRHGHAAVLTD------GKVYVIGGETKPGVR--TPLVTSAEVY 276
|
|
| NanM |
COG3055 |
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis]; |
334-534 |
2.18e-08 |
|
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442289 [Multi-domain] Cd Length: 277 Bit Score: 58.24 E-value: 2.18e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 334 LAGHAAALVDDVwLYVSGGR---TPHDLFssglfrFRLDSTSGGyWEQVIPAggrPPAATGHSMVFhAPSRALLVHGGhR 410
Cdd:COG3055 13 RSEAAAALLDGK-VYVAGGLsggSASNSF------EVYDPATNT-WSELAPL---PGPPRHHAAAV-AQDGKLYVFGG-F 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 411 PSTARFSVRVNSTELFHVDRHVWTTLKgrdglQGPRERAFHTASVLGNYMVVYGG---NVHTHYQEEkcyedgiffYHLG 487
Cdd:COG3055 80 TGANPSSTPLNDVYVYDPATNTWTKLA-----PMPTPRGGATALLLDGKIYVVGGwddGGNVAWVEV---------YDPA 145
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 145701025 488 CHQWVSGAELappgtpegraapPSGRYSHVAAVLGGSVLLVAGGYSG 534
Cdd:COG3055 146 TGTWTQLAPL------------PTPRDHLAAAVLPDGKILVIGGRNG 180
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1144-1189 |
1.85e-06 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 46.92 E-value: 1.85e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 145701025 1144 CQCNGHGDpRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAG 1189
Cdd:smart00180 1 CDCDPGGS-ASGTCDPDTGQCECKPNVTGRRCDRCAPGYYGDGPPG 45
|
|
| EGF_3 |
pfam12947 |
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ... |
1011-1045 |
1.86e-06 |
|
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.
Pssm-ID: 463759 [Multi-domain] Cd Length: 36 Bit Score: 46.44 E-value: 1.86e-06
10 20 30
....*....|....*....|....*....|....*
gi 145701025 1011 CRLGLARCHPRATCLNTPLSYECHCQRGYQGDGIS 1045
Cdd:pfam12947 1 CSDNNGGCHPNATCTNTGGSFTCTCNDGYTGDGVT 35
|
|
| NanM |
COG3055 |
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis]; |
1715-1799 |
2.38e-05 |
|
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442289 [Multi-domain] Cd Length: 277 Bit Score: 48.61 E-value: 2.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 1715 PRPRLFHASALLGDTMVVLGGRSDpDEFSSDVLLYQVNCNAWL-LPDLtrsasvgpPMEESVAHAVAAVGSRLYISGGFG 1793
Cdd:COG3055 10 PTPRSEAAAALLDGKVYVAGGLSG-GSASNSFEVYDPATNTWSeLAPL--------PGPPRHHAAAVAQDGKLYVFGGFT 80
|
....*.
gi 145701025 1794 GVALGR 1799
Cdd:COG3055 81 GANPSS 86
|
|
| EGF_CA |
smart00179 |
Calcium-binding EGF-like domain; |
1007-1040 |
1.00e-04 |
|
Calcium-binding EGF-like domain;
Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 41.85 E-value: 1.00e-04
10 20 30
....*....|....*....|....*....|....
gi 145701025 1007 DVDECRLGlARCHPRATCLNTPLSYECHCQRGYQ 1040
Cdd:smart00179 1 DIDECASG-NPCQNGGTCVNTVGSYRCECPPGYT 33
|
|
| Kelch_3 |
pfam13415 |
Galactose oxidase, central domain; |
1566-1613 |
1.18e-04 |
|
Galactose oxidase, central domain;
Pssm-ID: 433188 [Multi-domain] Cd Length: 49 Bit Score: 41.89 E-value: 1.18e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 145701025 1566 LLLVGGYSPENG-FNQQLLEYQLATGTWvsgAQSGTPPTGLYGHSAVYH 1613
Cdd:pfam13415 4 LYIFGGLGFDGQtRLNDLYVYDLDTNTW---TQIGDLPPPRSGHSATYI 49
|
|
| EGF_CA |
cd00054 |
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1007-1042 |
1.71e-04 |
|
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.
Pssm-ID: 238011 Cd Length: 38 Bit Score: 41.08 E-value: 1.71e-04
10 20 30
....*....|....*....|....*....|....*.
gi 145701025 1007 DVDECRLGlARCHPRATCLNTPLSYECHCQRGYQGD 1042
Cdd:cd00054 1 DIDECASG-NPCQNGGTCVNTVGSYRCSCPPGYTGR 35
|
|
| NanM |
COG3055 |
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis]; |
403-543 |
7.65e-04 |
|
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442289 [Multi-domain] Cd Length: 277 Bit Score: 43.99 E-value: 7.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 403 LLVHGGHRPSTArfsvrVNSTELFHVDRHVWTTLKGrdglqGPRERAFHTASVL-GNYMVVYGGNVHTHYQEEkcYEDGI 481
Cdd:COG3055 25 VYVAGGLSGGSA-----SNSFEVYDPATNTWSELAP-----LPGPPRHHAAAVAqDGKLYVFGGFTGANPSST--PLNDV 92
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 145701025 482 FFYHLGCHQWVSGAELappgtpegraapPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDLMAY 543
Cdd:COG3055 93 YVYDPATNTWTKLAPM------------PTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVY 142
|
|
| PLN02153 |
PLN02153 |
epithiospecifier protein |
1713-1791 |
8.79e-04 |
|
epithiospecifier protein
Pssm-ID: 177814 [Multi-domain] Cd Length: 341 Bit Score: 44.21 E-value: 8.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 1713 KEPRPRLFHASALLGDTMVVLGGRSDPDE-FSSDVLLYQVNCNAWLLPdltrSASVGPPMEESVAHAVAAVGSRLYISGG 1791
Cdd:PLN02153 18 KGPGPRCSHGIAVVGDKLYSFGGELKPNEhIDKDLYVFDFNTHTWSIA----PANGDVPRISCLGVRMVAVGTKLYIFGG 93
|
|
| Kelch_4 |
pfam13418 |
Galactose oxidase, central domain; |
227-276 |
9.44e-04 |
|
Galactose oxidase, central domain;
Pssm-ID: 433191 [Multi-domain] Cd Length: 49 Bit Score: 39.13 E-value: 9.44e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 145701025 227 ARIGAAgAFLSPPGLLAVFGGQDLNN-ALGDLVLYNFSANTWESwdLSPAP 276
Cdd:pfam13418 1 PRAYHT-STSIPDDTIYLFGGEGEDGtLLSDLWVFDLSTNEWTR--LGSLP 48
|
|
| EGF_CA |
pfam07645 |
Calcium-binding EGF domain; |
1007-1038 |
2.37e-03 |
|
Calcium-binding EGF domain;
Pssm-ID: 429571 Cd Length: 32 Bit Score: 37.60 E-value: 2.37e-03
10 20 30
....*....|....*....|....*....|..
gi 145701025 1007 DVDECRLGLARCHPRATCLNTPLSYECHCQRG 1038
Cdd:pfam07645 1 DVDECATGTHNCPANTVCVNTIGSFECRCPDG 32
|
|
| PSI |
pfam01437 |
Plexin repeat; A cysteine rich repeat found in several different extracellular receptors. The ... |
883-931 |
3.23e-03 |
|
Plexin repeat; A cysteine rich repeat found in several different extracellular receptors. The function of the repeat is unknown. Three copies of the repeat are found Plexin. Two copies of the repeat are found in mahogany protein. A related C. elegans protein contains four copies of the repeat. The Met receptor contains a single copy of the repeat. The Pfam alignment shows 6 conserved cysteine residues that may form three conserved disulphide bridges, whereas some members show 8 conserved cysteines. The pattern of conservation suggests that cysteines 5 and 7 (that are not absolutely conserved) form a disulphide bridge (Personal observation. A Bateman).
Pssm-ID: 396154 [Multi-domain] Cd Length: 52 Bit Score: 38.07 E-value: 3.23e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 145701025 883 CSQRLTCEDCL-ANSSQCAWCQSTHTCFLFAAYlaRYPHGGCRGWDDSVH 931
Cdd:pfam01437 2 CSQYTSCSSCLaARDPYCGWCSSEGRCVRRSAC--GAPEGNCEEWEQASS 49
|
|
| NanM |
COG3055 |
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis]; |
1715-1794 |
4.75e-03 |
|
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442289 [Multi-domain] Cd Length: 277 Bit Score: 41.68 E-value: 4.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 1715 PRPRLFH-ASALLGDTMVVLGGRSDPD---EFSSDVLLYQVNCNAWllpdltrsaSVGPPMEESVAHAVAAV-GSRLYIS 1789
Cdd:COG3055 57 PGPPRHHaAAVAQDGKLYVFGGFTGANpssTPLNDVYVYDPATNTW---------TKLAPMPTPRGGATALLlDGKIYVV 127
|
....*
gi 145701025 1790 GGFGG 1794
Cdd:COG3055 128 GGWDD 132
|
|
| Kelch_3 |
pfam13415 |
Galactose oxidase, central domain; |
240-286 |
4.97e-03 |
|
Galactose oxidase, central domain;
Pssm-ID: 433188 [Multi-domain] Cd Length: 49 Bit Score: 37.27 E-value: 4.97e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 145701025 240 GLLAVFGGQDL--NNALGDLVLYNFSANTWESwdLSPAPAARHSHVAVA 286
Cdd:pfam13415 2 DKLYIFGGLGFdgQTRLNDLYVYDLDTNTWTQ--IGDLPPPRSGHSATY 48
|
|
| PLN02153 |
PLN02153 |
epithiospecifier protein |
337-465 |
6.06e-03 |
|
epithiospecifier protein
Pssm-ID: 177814 [Multi-domain] Cd Length: 341 Bit Score: 41.51 E-value: 6.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145701025 337 HAAALVDDVwLYVSGGR-TPHDLFSSGLFRFRLDSTSggyWeQVIPAGGRPPAATGHSMVFHAPSRALLVHGGhRPSTAR 415
Cdd:PLN02153 26 HGIAVVGDK-LYSFGGElKPNEHIDKDLYVFDFNTHT---W-SIAPANGDVPRISCLGVRMVAVGTKLYIFGG-RDEKRE 99
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 145701025 416 FSvrvnstELFHVD--RHVWTTLKGRDGLQGPRERAFHTASVLGNYMVVYGG 465
Cdd:PLN02153 100 FS------DFYSYDtvKNEWTFLTKLDEEGGPEARTFHSMASDENHVYVFGG 145
|
|
| |
