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Conserved domains on  [gi|156104874|ref|NP_001979|]
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envoplakin isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SH3_10 pfam17902
SH3 domain; This entry represents an SH3 domain.
404-468 1.59e-26

SH3 domain; This entry represents an SH3 domain.


:

Pssm-ID: 407754  Cd Length: 65  Bit Score: 103.88  E-value: 1.59e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 156104874   404 PLPQRRNPPQQPLHVDSICDWDSGEVQLLQGERYKLVDNTDPHAWVVQGPGGETKRAPAACFCIP 468
Cdd:pfam17902    1 PLKQRRSPVTRPIPVKALCDYKQGEVTVEKGEECTLLDNSDREKWKVQTSSGVEKLVPSVCFLIP 65
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
908-1451 1.36e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 89.61  E-value: 1.36e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  908 AQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQrpLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRA 987
Cdd:COG1196   242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELE--LEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  988 GLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVErdpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKRE 1067
Cdd:COG1196   320 ELEEELAELEEELEELEEELEELEEELEEAEEELEE----AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1068 VDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEpKVIVKEVKKVEQDPG 1147
Cdd:COG1196   396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE-ALLELLAELLEEAAL 474
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1148 LLQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQRPKVQLQ---ERVHEIFQVDPETEQEI-TRLKAKLQEMAGK 1223
Cdd:COG1196   475 LEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglaGAVAVLIGVEAAYEAALeAALAAALQNIVVE 554
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1224 RSGVEKEVEKLLPDLEVLRA---QKPTVEYKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDE 1300
Cdd:COG1196   555 DDEVAAAAIEYLKAAKAGRAtflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1301 WRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKpEEKVVVQEVVVTQK 1380
Cdd:COG1196   635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL-LAEEEEERELAEAE 713
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 156104874 1381 DPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSkklAVERELRQLTLRIQELEK 1451
Cdd:COG1196   714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE---ELERELERLEREIEALGP 781
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1326-1679 4.33e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 4.33e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1326 LEKEAERLRQEvREAAQKRRAAEDAVYELQSKRLLLERRKpeekvvvqevvvtqkdpkLREEHSRLSGSLDEEVGRRRQL 1405
Cdd:COG1196   198 LERQLEPLERQ-AEKAERYRELKEELKELEAELLLLKLRE------------------LEAELEELEAELEELEAELEEL 258
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1406 ELEVQQLRAGVEEQegllsfqedRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEvvklEKDPDLEKSTEALRWDL 1485
Cdd:COG1196   259 EAELAELEAELEEL---------RLELEELELELEEAQAEEYELLAELARLEQDIARLE----ERRRELEERLEELEEEL 325
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1486 DQEKTQVTELNRECKNLQVQIDVLQKAKSQEKtiykEVIRVQKDRVLEDERARvwemLNRERTARQAREEEARRLRERID 1565
Cdd:COG1196   326 AELEEELEELEEELEELEEELEEAEEELEEAE----AELAEAEEALLEAEAEL----AEAEEELEELAEELLEALRAAAE 397
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1566 RAEtlgrtwsrEESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRGQELSRLEAAI 1645
Cdd:COG1196   398 LAA--------QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
                         330       340       350
                  ....*....|....*....|....*....|....
gi 156104874 1646 LREKDQIYEKERTLRDLHAKVSREELSQETQTRE 1679
Cdd:COG1196   470 EEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1858-1896 5.72e-10

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


:

Pssm-ID: 459901  Cd Length: 39  Bit Score: 56.18  E-value: 5.72e-10
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 156104874  1858 LLEAQAATGGIVDLLSRERYSVHKAMERGLIENTSTQRL 1896
Cdd:pfam00681    1 LLEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
481-1280 1.10e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.46  E-value: 1.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   481 LASELQALKQKLATVQSRLKASAVESLRpsqqapsgsdlANPQAQKLLTQMTRLDGDLGQIERQVLAWARAPLSRPTPLE 560
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEE-----------LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEIS 298
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   561 DLEGRIHSHEgtaQRLQSLGTEKETAQKECEAFLSTRpvgpaaLQLPVALNSVKNKFSDVQVLCSLYGEKAKAAL----D 636
Cdd:TIGR02168  299 RLEQQKQILR---ERLANLERQLEELEAQLEELESKL------DELAEELAELEEKLEELKEELESLEAELEELEaeleE 369
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   637 LERQIQDADRVIRGFEATLV----QEAPIPAEPGALQERVSELQRQRRELLEQQTCVLRlhralKASEHACAALQNNFQE 712
Cdd:TIGR02168  370 LESRLEELEEQLETLRSKVAqlelQIASLNNEIERLEARLERLEDRRERLQQEIEELLK-----KLEEAELKELQAELEE 444
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   713 FCQDLPRQQRQVRALTDRYHAVGDQLDLREKVVQDAALTYQQFKNCKDNLSSWLEHLprsqvrpSDGPSQIAYKLQAQKR 792
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL-------EGFSEGVKALLKNQSG 517
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   793 LT-------QEIQSRERDRATashLSQALQAALQDYELQ-ADTYRcsleptLAVSAPKRP---RVAPLQES------IQA 855
Cdd:TIGR02168  518 LSgilgvlsELISVDEGYEAA---IEAALGGRLQAVVVEnLNAAK------KAIAFLKQNelgRVTFLPLDsikgteIQG 588
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   856 QEKNLAKAYTEVAAAQQQLLQQLEFARKMLE------------------KKELSE---------DIRRTHDAKQGSESPA 908
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddldnalelAKKLRPgyrivtldgDLVRPGGVITGGSAKT 668
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   909 QAG-----RESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEfyRDPQLEGSLSRVKAQVEEEG 983
Cdd:TIGR02168  669 NSSilerrREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR--QISALRKDLARLEAEVEQLE 746
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   984 KRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVErdpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLAL 1063
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE----LEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1064 EKREVdvkekvvvkevvkveknlEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEpkvivkevkkvE 1143
Cdd:TIGR02168  823 RERLE------------------SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE-----------S 873
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1144 QDPGLLQESSRLRSLLEEERTKNATLARELSDLHSKysVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGk 1223
Cdd:TIGR02168  874 ELEALLNERASLEEALALLRSELEELSEELRELESK--RSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS- 950
                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 156104874  1224 rsgvekevekllpdlevlraqkptVEYKEVTQEVVRHERSPEVLR-EIDRLKAQLNEL 1280
Cdd:TIGR02168  951 ------------------------LTLEEAEALENKIEDDEEEARrRLKRLENKIKEL 984
PLEC smart00250
Plectin repeat;
1894-1931 8.57e-08

Plectin repeat;


:

Pssm-ID: 197605  Cd Length: 38  Bit Score: 49.79  E-value: 8.57e-08
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 156104874   1894 QRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESV 1931
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
SPEC super family cl02488
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ...
228-415 1.21e-07

Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here


The actual alignment was detected with superfamily member cd00176:

Pssm-ID: 413338 [Multi-domain]  Cd Length: 213  Bit Score: 54.37  E-value: 1.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  228 LYTHLQGCTRQLSALAEQQRRILQQDwsDLMADPAGVRREYEHFK--QHELLSQEQSVNQLEDDGERMVELRHPAVGPIQ 305
Cdd:cd00176     1 KLQQFLRDADELEAWLSEKEELLSST--DYGDDLESVEALLKKHEalEAELAAHEERVEALNELGEQLIEEGHPDAEEIQ 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  306 AHQEALKMEWQNFLNLCICQETQLQHVEDYRRFQEEADSVSQTLAKLNSNLDakySPAPGGPPGAPTELLQQLEAEEKRL 385
Cdd:cd00176    79 ERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEEKEAALA---SEDLGKDLESVEELLKKHKELEEEL 155
                         170       180       190
                  ....*....|....*....|....*....|
gi 156104874  386 avtERATGDLQRRSRDVAPLPQRRNPPQQP 415
Cdd:cd00176   156 ---EAHEPRLKSLNELAEELLEEGHPDADE 182
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1935-1972 1.47e-07

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


:

Pssm-ID: 459901  Cd Length: 39  Bit Score: 49.25  E-value: 1.47e-07
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 156104874  1935 LQVQHLTGGLIDPKRTGRIPIQQALLSGMISEELAQLL 1972
Cdd:pfam00681    2 LEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1688-1716 1.36e-04

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


:

Pssm-ID: 459901  Cd Length: 39  Bit Score: 40.77  E-value: 1.36e-04
                           10        20
                   ....*....|....*....|....*....
gi 156104874  1688 ILEPETGKDMSPYEAYKRGIIDRGQYLQL 1716
Cdd:pfam00681   11 IIDPVTGERLSVEEAVKRGLIDPETAQKL 39
PLEC smart00250
Plectin repeat;
1818-1855 2.78e-04

Plectin repeat;


:

Pssm-ID: 197605  Cd Length: 38  Bit Score: 40.16  E-value: 2.78e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 156104874   1818 LGLGDDSFPIAGIYDTTTDNKCSIKTAVAKNMLDPITG 1855
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
 
Name Accession Description Interval E-value
SH3_10 pfam17902
SH3 domain; This entry represents an SH3 domain.
404-468 1.59e-26

SH3 domain; This entry represents an SH3 domain.


Pssm-ID: 407754  Cd Length: 65  Bit Score: 103.88  E-value: 1.59e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 156104874   404 PLPQRRNPPQQPLHVDSICDWDSGEVQLLQGERYKLVDNTDPHAWVVQGPGGETKRAPAACFCIP 468
Cdd:pfam17902    1 PLKQRRSPVTRPIPVKALCDYKQGEVTVEKGEECTLLDNSDREKWKVQTSSGVEKLVPSVCFLIP 65
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
908-1451 1.36e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 89.61  E-value: 1.36e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  908 AQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQrpLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRA 987
Cdd:COG1196   242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELE--LEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  988 GLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVErdpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKRE 1067
Cdd:COG1196   320 ELEEELAELEEELEELEEELEELEEELEEAEEELEE----AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1068 VDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEpKVIVKEVKKVEQDPG 1147
Cdd:COG1196   396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE-ALLELLAELLEEAAL 474
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1148 LLQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQRPKVQLQ---ERVHEIFQVDPETEQEI-TRLKAKLQEMAGK 1223
Cdd:COG1196   475 LEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglaGAVAVLIGVEAAYEAALeAALAAALQNIVVE 554
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1224 RSGVEKEVEKLLPDLEVLRA---QKPTVEYKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDE 1300
Cdd:COG1196   555 DDEVAAAAIEYLKAAKAGRAtflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1301 WRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKpEEKVVVQEVVVTQK 1380
Cdd:COG1196   635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL-LAEEEEERELAEAE 713
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 156104874 1381 DPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSkklAVERELRQLTLRIQELEK 1451
Cdd:COG1196   714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE---ELERELERLEREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
912-1645 2.59e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.95  E-value: 2.59e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   912 RESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQrpLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQA 991
Cdd:TIGR02168  260 AELQELEEKLEELRLEVSELEEEIEELQKELYALANE--ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   992 DLEVAAQKVVQLESKRKTMQPHLLTKEVTQVERDPGLDSQAAQLRIQ---IQQLRGEDAVISARLEGLKKELLALEKREV 1068
Cdd:TIGR02168  338 ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLrskVAQLELQIASLNNEIERLEARLERLEDRRE 417
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1069 DVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDA-ARRKQAEEAVAKLQARIEDLERAISSVEPKvivkevkkveqdpg 1147
Cdd:TIGR02168  418 RLQQEIEELLKKLEEAELKELQAELEELEEELEELqEELERLEEALEELREELEEAEQALDAAERE-------------- 483
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1148 LLQESSRLRSlLEEERTKNATLARELSdlhskySVVEKQRPKVQLQERVHEIFQVDPETEQEI-TRLKAKLQEMAGKR-S 1225
Cdd:TIGR02168  484 LAQLQARLDS-LERLQENLEGFSEGVK------ALLKNQSGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENlN 556
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1226 GVEKEVEKLLPD---------LEVLRAQKPTVEYKEVTQEV-------VRHERSPEVLRE-----------IDRLKAQLN 1278
Cdd:TIGR02168  557 AAKKAIAFLKQNelgrvtflpLDSIKGTEIQGNDREILKNIegflgvaKDLVKFDPKLRKalsyllggvlvVDDLDNALE 636
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1279 ELVNSHGRsqEQLIRLQGERDEWRRERAKVETKTVSKEVVRhekdpvlEKEAERLRQEVREAAQKRRAAEDAVYELQSKr 1358
Cdd:TIGR02168  637 LAKKLRPG--YRIVTLDGDLVRPGGVITGGSAKTNSSILER-------RREIEELEEKIEELEEKIAELEKALAELRKE- 706
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1359 lLLERRKPEEKVVVQEVVVTQKDPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLsfQEDRSKKLAVERE 1438
Cdd:TIGR02168  707 -LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERL--EEAEEELAEAEAE 783
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1439 LRQLTLRIQELEKRPPTVQEKI-IMEEVVKLEKDP--DLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKA-KS 1514
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALdELRAELTLLNEEaaNLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEiEE 863
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1515 QEKTIYKEVIRVQKdrvLEDERARVWEMLNRERTARQAREEEARRLRERIDRAEtlgrtwsREESELQRARDQADQECGR 1594
Cdd:TIGR02168  864 LEELIEELESELEA---LLNERASLEEALALLRSELEELSEELRELESKRSELR-------RELEELREKLAQLELRLEG 933
                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 156104874  1595 LQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRgqeLSRLEAAI 1645
Cdd:TIGR02168  934 LEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRR---LKRLENKI 981
PTZ00121 PTZ00121
MAEBL; Provisional
879-1662 1.84e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 73.25  E-value: 1.84e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  879 EFARKMLEKKELSEDIRRTHDAKQGSEspaqAGRESEALKAqleEERKRVARVQHELEAQRSQllQLRTQRPLERLEE-K 957
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAED----ARKAEEARKA---EDAKRVEIARKAEDARKAE--EARKAEDAKKAEAaR 1182
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  958 EVVEFYRDPQLEgslsrvkaQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQphllTKEVTQVERDPGLDSQAAQLRI 1037
Cdd:PTZ00121 1183 KAEEVRKAEELR--------KAEDARKAEAARKAEEERKAEEARKAEDAKKAEA----VKKAEEAKKDAEEAKKAEEERN 1250
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1038 QIQQLRGEDAVIsARLEGLKKELLALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEdaarRKQAEEAVAKLQ 1117
Cdd:PTZ00121 1251 NEEIRKFEEARM-AHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEE----AKKADEAKKKAE 1325
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1118 ARIEDLERAISSVEPKVIVKEVKKVEqdpgllqessrlrsllEEERTKNATLARELSDLHSKYSVVEKQRPKvQLQERVH 1197
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAE----------------AEAAADEAEAAEEKAEAAEKKKEEAKKKAD-AAKKKAE 1388
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1198 EIFQVDpeteqeitRLKAKLQEMAGKRSGVEKEVEkllpdlevlrAQKPTVEYKEVTQEVVRHE---RSPEVLREIDRLK 1274
Cdd:PTZ00121 1389 EKKKAD--------EAKKKAEEDKKKADELKKAAA----------AKKKADEAKKKAEEKKKADeakKKAEEAKKADEAK 1450
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1275 AQLNElvnshGRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRHEKdpvlekEAERLRQEVREAAQKRRAAEDAvYEL 1354
Cdd:PTZ00121 1451 KKAEE-----AKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE------EAKKKADEAKKAAEAKKKADEA-KKA 1518
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1355 QSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLA 1434
Cdd:PTZ00121 1519 EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVM 1598
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1435 VERElRQLTLRIQELEKRPptvQEKIIMEEVVKLEkdpDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKS 1514
Cdd:PTZ00121 1599 KLYE-EEKKMKAEEAKKAE---EAKIKAEELKKAE---EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAE 1671
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1515 QEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAREEEARRlreridRAETLGRTWSREESELQRARDQADQEcGR 1594
Cdd:PTZ00121 1672 EDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKK------KAEELKKAEEENKIKAEEAKKEAEED-KK 1744
                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1595 LQQELRALErqkqqqtlqlqEESKLLSQKTESERQKAAQRGQELSRLEAAILREKDQI--YEKERTLRDL 1662
Cdd:PTZ00121 1745 KAEEAKKDE-----------EEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKrrMEVDKKIKDI 1803
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
917-1688 2.53e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 66.15  E-value: 2.53e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   917 LKAQLEEERKRVARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQADLEVA 996
Cdd:pfam02463  167 LKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELL 246
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   997 AQKVVQLESKRKTMQPHllTKEVTQVERDPGLDSQaaqlriQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVV- 1075
Cdd:pfam02463  247 RDEQEEIESSKQEIEKE--EEKLAQVLKENKEEEK------EKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKe 318
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1076 -VKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKKVEQDPGLLQESSR 1154
Cdd:pfam02463  319 sEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE 398
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1155 LRSLLEEERTKNATLAR----ELSDLHSKYSVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQemagkrsgvEKE 1230
Cdd:pfam02463  399 LKSEEEKEAQLLLELARqledLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELE---------LKK 469
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1231 VEKLLPDLEVLraqkptveyKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVET 1310
Cdd:pfam02463  470 SEDLLKETQLV---------KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN 540
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1311 KTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHS- 1389
Cdd:pfam02463  541 YKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDk 620
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1390 -RLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEVVKL 1468
Cdd:pfam02463  621 rAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLE 700
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1469 EKDPDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEKTIYKEvIRVQKDRVLEDERARVWEMLNRERT 1548
Cdd:pfam02463  701 IKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEK-SRLKKEEKEEEKSELSLKEKELAEE 779
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1549 ARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKtESER 1628
Cdd:pfam02463  780 REKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEE-ELER 858
                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1629 QKAAQRGQELSRLEAAILREKDQIYEKERTLrDLHAKVSREELSQETQTRETNLSTKISI 1688
Cdd:pfam02463  859 LEEEITKEELLQELLLKEEELEEQKLKDELE-SKEEKEKEEKKELEEESQKLNLLEEKEN 917
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1326-1679 4.33e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 4.33e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1326 LEKEAERLRQEvREAAQKRRAAEDAVYELQSKRLLLERRKpeekvvvqevvvtqkdpkLREEHSRLSGSLDEEVGRRRQL 1405
Cdd:COG1196   198 LERQLEPLERQ-AEKAERYRELKEELKELEAELLLLKLRE------------------LEAELEELEAELEELEAELEEL 258
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1406 ELEVQQLRAGVEEQegllsfqedRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEvvklEKDPDLEKSTEALRWDL 1485
Cdd:COG1196   259 EAELAELEAELEEL---------RLELEELELELEEAQAEEYELLAELARLEQDIARLE----ERRRELEERLEELEEEL 325
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1486 DQEKTQVTELNRECKNLQVQIDVLQKAKSQEKtiykEVIRVQKDRVLEDERARvwemLNRERTARQAREEEARRLRERID 1565
Cdd:COG1196   326 AELEEELEELEEELEELEEELEEAEEELEEAE----AELAEAEEALLEAEAEL----AEAEEELEELAEELLEALRAAAE 397
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1566 RAEtlgrtwsrEESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRGQELSRLEAAI 1645
Cdd:COG1196   398 LAA--------QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
                         330       340       350
                  ....*....|....*....|....*....|....
gi 156104874 1646 LREKDQIYEKERTLRDLHAKVSREELSQETQTRE 1679
Cdd:COG1196   470 EEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1858-1896 5.72e-10

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 56.18  E-value: 5.72e-10
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 156104874  1858 LLEAQAATGGIVDLLSRERYSVHKAMERGLIENTSTQRL 1896
Cdd:pfam00681    1 LLEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
481-1280 1.10e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.46  E-value: 1.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   481 LASELQALKQKLATVQSRLKASAVESLRpsqqapsgsdlANPQAQKLLTQMTRLDGDLGQIERQVLAWARAPLSRPTPLE 560
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEE-----------LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEIS 298
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   561 DLEGRIHSHEgtaQRLQSLGTEKETAQKECEAFLSTRpvgpaaLQLPVALNSVKNKFSDVQVLCSLYGEKAKAAL----D 636
Cdd:TIGR02168  299 RLEQQKQILR---ERLANLERQLEELEAQLEELESKL------DELAEELAELEEKLEELKEELESLEAELEELEaeleE 369
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   637 LERQIQDADRVIRGFEATLV----QEAPIPAEPGALQERVSELQRQRRELLEQQTCVLRlhralKASEHACAALQNNFQE 712
Cdd:TIGR02168  370 LESRLEELEEQLETLRSKVAqlelQIASLNNEIERLEARLERLEDRRERLQQEIEELLK-----KLEEAELKELQAELEE 444
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   713 FCQDLPRQQRQVRALTDRYHAVGDQLDLREKVVQDAALTYQQFKNCKDNLSSWLEHLprsqvrpSDGPSQIAYKLQAQKR 792
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL-------EGFSEGVKALLKNQSG 517
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   793 LT-------QEIQSRERDRATashLSQALQAALQDYELQ-ADTYRcsleptLAVSAPKRP---RVAPLQES------IQA 855
Cdd:TIGR02168  518 LSgilgvlsELISVDEGYEAA---IEAALGGRLQAVVVEnLNAAK------KAIAFLKQNelgRVTFLPLDsikgteIQG 588
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   856 QEKNLAKAYTEVAAAQQQLLQQLEFARKMLE------------------KKELSE---------DIRRTHDAKQGSESPA 908
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddldnalelAKKLRPgyrivtldgDLVRPGGVITGGSAKT 668
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   909 QAG-----RESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEfyRDPQLEGSLSRVKAQVEEEG 983
Cdd:TIGR02168  669 NSSilerrREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR--QISALRKDLARLEAEVEQLE 746
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   984 KRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVErdpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLAL 1063
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE----LEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1064 EKREVdvkekvvvkevvkveknlEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEpkvivkevkkvE 1143
Cdd:TIGR02168  823 RERLE------------------SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE-----------S 873
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1144 QDPGLLQESSRLRSLLEEERTKNATLARELSDLHSKysVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGk 1223
Cdd:TIGR02168  874 ELEALLNERASLEEALALLRSELEELSEELRELESK--RSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS- 950
                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 156104874  1224 rsgvekevekllpdlevlraqkptVEYKEVTQEVVRHERSPEVLR-EIDRLKAQLNEL 1280
Cdd:TIGR02168  951 ------------------------LTLEEAEALENKIEDDEEEARrRLKRLENKIKEL 984
PLEC smart00250
Plectin repeat;
1894-1931 8.57e-08

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 49.79  E-value: 8.57e-08
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 156104874   1894 QRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESV 1931
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
SPEC cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ...
228-415 1.21e-07

Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here


Pssm-ID: 238103 [Multi-domain]  Cd Length: 213  Bit Score: 54.37  E-value: 1.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  228 LYTHLQGCTRQLSALAEQQRRILQQDwsDLMADPAGVRREYEHFK--QHELLSQEQSVNQLEDDGERMVELRHPAVGPIQ 305
Cdd:cd00176     1 KLQQFLRDADELEAWLSEKEELLSST--DYGDDLESVEALLKKHEalEAELAAHEERVEALNELGEQLIEEGHPDAEEIQ 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  306 AHQEALKMEWQNFLNLCICQETQLQHVEDYRRFQEEADSVSQTLAKLNSNLDakySPAPGGPPGAPTELLQQLEAEEKRL 385
Cdd:cd00176    79 ERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEEKEAALA---SEDLGKDLESVEELLKKHKELEEEL 155
                         170       180       190
                  ....*....|....*....|....*....|
gi 156104874  386 avtERATGDLQRRSRDVAPLPQRRNPPQQP 415
Cdd:cd00176   156 ---EAHEPRLKSLNELAEELLEEGHPDADE 182
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1935-1972 1.47e-07

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 49.25  E-value: 1.47e-07
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 156104874  1935 LQVQHLTGGLIDPKRTGRIPIQQALLSGMISEELAQLL 1972
Cdd:pfam00681    2 LEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
PLEC smart00250
Plectin repeat;
1856-1889 6.58e-07

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 47.48  E-value: 6.58e-07
                            10        20        30
                    ....*....|....*....|....*....|....
gi 156104874   1856 QKLLEAQAATGGIVDLLSRERYSVHKAMERGLIE 1889
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLID 34
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
629-1132 8.94e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.09  E-value: 8.94e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  629 EKAKAALDLERQIQDADRVIRGFEATLVQEApipAEPGALQERVSELQRQRRELLEQqtcVLRLHRALKASEHACAALQN 708
Cdd:COG1196   243 ELEAELEELEAELEELEAELAELEAELEELR---LELEELELELEEAQAEEYELLAE---LARLEQDIARLEERRRELEE 316
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  709 NFQEFCQDLPRQQRQVRALTDRYHAVGDQLDLREKVVQDAALTYQQFKN-----------CKDNLSSWLEHLPRSQVRPS 777
Cdd:COG1196   317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEalleaeaelaeAEEELEELAEELLEALRAAA 396
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  778 DGPSQIAYKLQAQKRLTQEIQSRERDRATASHLSQALQAALQDYELQADTYRCSLEPTLAVSAPKRPRVAPLQESIQAQE 857
Cdd:COG1196   397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  858 KNLAKAYTEVAAAQQQLLQQLEFARKM---------LEKKELSEDIRRTHDAKQGSESPAQAGRESEALKAQLEEERKRV 928
Cdd:COG1196   477 AALAELLEELAEAAARLLLLLEAEADYegflegvkaALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD 556
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  929 ARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLEGSLSR-VKAQVEEEGKRRAGLQADLEVAAQKVVQLESKR 1007
Cdd:COG1196   557 EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDlVASDLREADARYYVLGDTLLGRTLVAARLEAAL 636
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1008 KTMQPHLLTKEVTQVERDPGLDSQA-----------AQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVV 1076
Cdd:COG1196   637 RRAVTLAGRLREVTLEGEGGSAGGSltggsrrellaALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 156104874 1077 KEVVKVEKNLEMVKAAQALRLQME---------EDAARRKQAEEAVAKLQARIEDLERAISSVEP 1132
Cdd:COG1196   717 LEEELEEEALEEQLEAEREELLEElleeeelleEEALEELPEPPDLEELERELERLEREIEALGP 781
SPEC smart00150
Spectrin repeats;
237-330 9.66e-05

Spectrin repeats;


Pssm-ID: 197544 [Multi-domain]  Cd Length: 101  Bit Score: 43.47  E-value: 9.66e-05
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874    237 RQLSALAEQQRRILQQDwsDLMADPAGVRREYEHFK--QHELLSQEQSVNQLEDDGERMVELRHPAVGPIQAHQEALKME 314
Cdd:smart00150    8 DELEAWLEEKEQLLASE--DLGKDLESVEALLKKHEafEAELEAHEERVEALNELGEQLIEEGHPDAEEIEERLEELNER 85
                            90
                    ....*....|....*.
gi 156104874    315 WQNFLNLCICQETQLQ 330
Cdd:smart00150   86 WEELKELAEERRQKLE 101
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1688-1716 1.36e-04

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 40.77  E-value: 1.36e-04
                           10        20
                   ....*....|....*....|....*....
gi 156104874  1688 ILEPETGKDMSPYEAYKRGIIDRGQYLQL 1716
Cdd:pfam00681   11 IIDPVTGERLSVEEAVKRGLIDPETAQKL 39
PLEC smart00250
Plectin repeat;
1818-1855 2.78e-04

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 40.16  E-value: 2.78e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 156104874   1818 LGLGDDSFPIAGIYDTTTDNKCSIKTAVAKNMLDPITG 1855
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
PLEC smart00250
Plectin repeat;
1932-1969 6.93e-04

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 39.00  E-value: 6.93e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 156104874   1932 LPHLQVQHLTGGLIDPKRTGRIPIQQALLSGMISEELA 1969
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
1408-1718 2.35e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.18  E-value: 2.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1408 EVQQLRAGVEEQEGLLSFQED-------RSKKLAVERELRQLTLRIQELEKRPPTVQEKIimeEVVKLEKDPDLE----- 1475
Cdd:pfam15921  188 EIRSILVDFEEASGKKIYEHDsmstmhfRSLGSAISKILRELDTEISYLKGRIFPVEDQL---EALKSESQNKIElllqq 264
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1476 --KSTEALRWDLDQEKTQVTE----LNRECKNLQVQIDVLQKAKSQEKTIYKevirvqkdRVLEDERARVWEMLNRERTA 1549
Cdd:pfam15921  265 hqDRIEQLISEHEVEITGLTEkassARSQANSIQSQLEIIQEQARNQNSMYM--------RQLSDLESTVSQLRSELREA 336
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1550 RQAREeearrlreriDRAETLGRTWSREESELQRAR---DQADQECG----RLQQELRALERQKQQQTLQLQEESKLLSQ 1622
Cdd:pfam15921  337 KRMYE----------DKIEELEKQLVLANSELTEARterDQFSQESGnlddQLQKLLADLHKREKELSLEKEQNKRLWDR 406
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1623 KTESE------RQKAAQRGQELSRLEAAILREKDQIY-EKERTLRDLHAK-VSREELSQETQTRETNLSTKISILEPETG 1694
Cdd:pfam15921  407 DTGNSitidhlRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKnESLEKVSSLTAQLESTKEMLRKVVEELTA 486
                          330       340
                   ....*....|....*....|....
gi 156104874  1695 KDMSpYEAYKRGIIDRGQYLQLQE 1718
Cdd:pfam15921  487 KKMT-LESSERTVSDLTASLQEKE 509
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1385-1707 2.40e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 2.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1385 REEHSRLSGSLDEEVGRRRQLElEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRqltLRIQELEKRPPTVQEKIIMEE 1464
Cdd:TIGR02169  156 RKIIDEIAGVAEFDRKKEKALE-ELEEVEENIERLDLIIDEKRQQLERLRREREKA---ERYQALLKEKREYEGYELLKE 231
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1465 VVKLEKD-PDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDvlQKAKSQEKTIYKEVIRVQKD-RVLEDERARVWEM 1542
Cdd:TIGR02169  232 KEALERQkEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE--ELNKKIKDLGEEEQLRVKEKiGELEAEIASLERS 309
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1543 LNRERTARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERqkqqQTLQLQEESKLLSQ 1622
Cdd:TIGR02169  310 IAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA----ELEEVDKEFAETRD 385
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1623 KTESERQKAAQRGQELSRLEAAILREKDQIYEKERTLRDLHAKVSR-EELSQETQTRETNLSTKISILEPE---TGKDMS 1698
Cdd:TIGR02169  386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGiEAKINELEEEKEDKALEIKKQEWKleqLAADLS 465

                   ....*....
gi 156104874  1699 PYEAYKRGI 1707
Cdd:TIGR02169  466 KYEQELYDL 474
PLEC smart00250
Plectin repeat;
1688-1713 5.42e-03

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 36.31  E-value: 5.42e-03
                            10        20
                    ....*....|....*....|....*.
gi 156104874   1688 ILEPETGKDMSPYEAYKRGIIDRGQY 1713
Cdd:smart00250   13 IIDPETGQKLSVEEALRRGLIDPETG 38
 
Name Accession Description Interval E-value
SH3_10 pfam17902
SH3 domain; This entry represents an SH3 domain.
404-468 1.59e-26

SH3 domain; This entry represents an SH3 domain.


Pssm-ID: 407754  Cd Length: 65  Bit Score: 103.88  E-value: 1.59e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 156104874   404 PLPQRRNPPQQPLHVDSICDWDSGEVQLLQGERYKLVDNTDPHAWVVQGPGGETKRAPAACFCIP 468
Cdd:pfam17902    1 PLKQRRSPVTRPIPVKALCDYKQGEVTVEKGEECTLLDNSDREKWKVQTSSGVEKLVPSVCFLIP 65
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
908-1451 1.36e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 89.61  E-value: 1.36e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  908 AQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQrpLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRA 987
Cdd:COG1196   242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELE--LEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  988 GLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVErdpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKRE 1067
Cdd:COG1196   320 ELEEELAELEEELEELEEELEELEEELEEAEEELEE----AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1068 VDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEpKVIVKEVKKVEQDPG 1147
Cdd:COG1196   396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE-ALLELLAELLEEAAL 474
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1148 LLQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQRPKVQLQ---ERVHEIFQVDPETEQEI-TRLKAKLQEMAGK 1223
Cdd:COG1196   475 LEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglaGAVAVLIGVEAAYEAALeAALAAALQNIVVE 554
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1224 RSGVEKEVEKLLPDLEVLRA---QKPTVEYKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDE 1300
Cdd:COG1196   555 DDEVAAAAIEYLKAAKAGRAtflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1301 WRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKpEEKVVVQEVVVTQK 1380
Cdd:COG1196   635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL-LAEEEEERELAEAE 713
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 156104874 1381 DPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSkklAVERELRQLTLRIQELEK 1451
Cdd:COG1196   714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE---ELERELERLEREIEALGP 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
915-1498 1.70e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.14  E-value: 1.70e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  915 EALKaQLEEERKRVARVQ---HELEAQRSQL----------LQLRtqrplERLEEKEVVE-FYRDPQLEGSLSRVKAQVE 980
Cdd:COG1196   176 EAER-KLEATEENLERLEdilGELERQLEPLerqaekaeryRELK-----EELKELEAELlLLKLRELEAELEELEAELE 249
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  981 EEGKRRAGLQADLEVAAQKVVQLESKRKTMQphLLTKEVTQVERDpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKEL 1060
Cdd:COG1196   250 ELEAELEELEAELAELEAELEELRLELEELE--LELEEAQAEEYE--LLAELARLEQDIARLEERRRELEERLEELEEEL 325
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1061 LALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVK 1140
Cdd:COG1196   326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL 405
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1141 KVEQDpGLLQESSRLRSLLEEERTKNATLARELSDLHSKYS-----VVEKQRPKVQLQERVHEIFQVDPETEQEITRLKA 1215
Cdd:COG1196   406 EEAEE-ALLERLERLEEELEELEEALAELEEEEEEEEEALEeaaeeEAELEEEEEALLELLAELLEEAALLEAALAELLE 484
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1216 KLQEMAGKRSGVEKEVEKLLPDLEVLRAQKPTVEYKEVTQEVVRHERSPEVLRE--IDRLKAQLNELVNSHGRSQEQLIR 1293
Cdd:COG1196   485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAalEAALAAALQNIVVEDDEVAAAAIE 564
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1294 LQGERDEWRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQ 1373
Cdd:COG1196   565 YLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAG 644
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1374 EVVVTQKD-----PKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERE-LRQLTLRIQ 1447
Cdd:COG1196   645 RLREVTLEgeggsAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEeRLEEELEEE 724
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 156104874 1448 ELEKRPPTVQEKIIMEEVVKLEKDPDLEKSTEALRWDLDQEKTQVTELNRE 1498
Cdd:COG1196   725 ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
912-1645 2.59e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.95  E-value: 2.59e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   912 RESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQrpLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQA 991
Cdd:TIGR02168  260 AELQELEEKLEELRLEVSELEEEIEELQKELYALANE--ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   992 DLEVAAQKVVQLESKRKTMQPHLLTKEVTQVERDPGLDSQAAQLRIQ---IQQLRGEDAVISARLEGLKKELLALEKREV 1068
Cdd:TIGR02168  338 ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLrskVAQLELQIASLNNEIERLEARLERLEDRRE 417
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1069 DVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDA-ARRKQAEEAVAKLQARIEDLERAISSVEPKvivkevkkveqdpg 1147
Cdd:TIGR02168  418 RLQQEIEELLKKLEEAELKELQAELEELEEELEELqEELERLEEALEELREELEEAEQALDAAERE-------------- 483
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1148 LLQESSRLRSlLEEERTKNATLARELSdlhskySVVEKQRPKVQLQERVHEIFQVDPETEQEI-TRLKAKLQEMAGKR-S 1225
Cdd:TIGR02168  484 LAQLQARLDS-LERLQENLEGFSEGVK------ALLKNQSGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENlN 556
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1226 GVEKEVEKLLPD---------LEVLRAQKPTVEYKEVTQEV-------VRHERSPEVLRE-----------IDRLKAQLN 1278
Cdd:TIGR02168  557 AAKKAIAFLKQNelgrvtflpLDSIKGTEIQGNDREILKNIegflgvaKDLVKFDPKLRKalsyllggvlvVDDLDNALE 636
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1279 ELVNSHGRsqEQLIRLQGERDEWRRERAKVETKTVSKEVVRhekdpvlEKEAERLRQEVREAAQKRRAAEDAVYELQSKr 1358
Cdd:TIGR02168  637 LAKKLRPG--YRIVTLDGDLVRPGGVITGGSAKTNSSILER-------RREIEELEEKIEELEEKIAELEKALAELRKE- 706
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1359 lLLERRKPEEKVVVQEVVVTQKDPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLsfQEDRSKKLAVERE 1438
Cdd:TIGR02168  707 -LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERL--EEAEEELAEAEAE 783
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1439 LRQLTLRIQELEKRPPTVQEKI-IMEEVVKLEKDP--DLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKA-KS 1514
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALdELRAELTLLNEEaaNLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEiEE 863
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1515 QEKTIYKEVIRVQKdrvLEDERARVWEMLNRERTARQAREEEARRLRERIDRAEtlgrtwsREESELQRARDQADQECGR 1594
Cdd:TIGR02168  864 LEELIEELESELEA---LLNERASLEEALALLRSELEELSEELRELESKRSELR-------RELEELREKLAQLELRLEG 933
                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 156104874  1595 LQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRgqeLSRLEAAI 1645
Cdd:TIGR02168  934 LEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRR---LKRLENKI 981
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
908-1702 2.52e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.87  E-value: 2.52e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   908 AQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQRP-----LERLEEKEVVEFY----RDPQLEGSLSRVKAQ 978
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREkaeryQALLKEKREYEGYellkEKEALERQKEAIERQ 245
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   979 VEEEGKRRAGLQADLEVAAQKVVQLESKRKTmqphlLTKEVtqverDPGLDSQAAQLRIQIQQLRGEDAVISARLEglkk 1058
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEE-----LNKKI-----KDLGEEEQLRVKEKIGELEAEIASLERSIA---- 311
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1059 ellalekrevdvkekvvvkevvkveknlemvkaaqALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKE 1138
Cdd:TIGR02169  312 -----------------------------------EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLT 356
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1139 VKKVEqdpgLLQESSRLRSLLEEERTKNATLARELSDLHSKYSVV-----EKQRPKVQLQERVHEIFQVDPETEQEITRL 1213
Cdd:TIGR02169  357 EEYAE----LKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLkreinELKRELDRLQEELQRLSEELADLNAAIAGI 432
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1214 KAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKPTVEYK----EVTQEVVRHERSpEVLREIDRLKAQLNELVNS--HGRS 1287
Cdd:TIGR02169  433 EAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQElydlKEEYDRVEKELS-KLQRELAEAEAQARASEERvrGGRA 511
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1288 QEQLIR--------LQGERDEWRRERAK-VETKTVSK-EVVRHEKDPVLEKEAERLRQEvreaaQKRRAAEDAVYELQSK 1357
Cdd:TIGR02169  512 VEEVLKasiqgvhgTVAQLGSVGERYATaIEVAAGNRlNNVVVEDDAVAKEAIELLKRR-----KAGRATFLPLNKMRDE 586
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1358 RLLLERRKPEEKVVVQEVVVTQkDPKLREEHSRLSGSL----DEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKL 1433
Cdd:TIGR02169  587 RRDLSILSEDGVIGFAVDLVEF-DPKYEPAFKYVFGDTlvveDIEAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGG 665
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1434 AV-----ERELRQLTLRIQELEKrpptvQEKIIMEEVVKLEKD--------PDLEKSTEALRWDLDQEKTQVTELNRECK 1500
Cdd:TIGR02169  666 ILfsrsePAELQRLRERLEGLKR-----ELSSLQSELRRIENRldelsqelSDASRKIGEIEKEIEQLEQEEEKLKERLE 740
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1501 NLQVQIDVLQKAKSQEKTIYKEVIRV--QKDRVLEDERARVWEMLNRERTAR-QAREEEARRLRERIDRAETLGRTWSRE 1577
Cdd:TIGR02169  741 ELEEDLSSLEQEIENVKSELKELEARieELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIEQK 820
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1578 ESELQRARDQADQECGRLQQELRALE-RQKQQQTLQLQEESKLLSQKTESERQKAAQR--GQELSRLEAAILREKDQIYE 1654
Cdd:TIGR02169  821 LNRLTLEKEYLEKEIQELQEQRIDLKeQIKSIEKEIENLNGKKEELEEELEELEAALRdlESRLGDLKKERDELEAQLRE 900
                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 156104874  1655 KERTLRDLHAKVSREELSQ-ETQTRETNLSTKISILEPETGKDMSPYEA 1702
Cdd:TIGR02169  901 LERKIEELEAQIEKKRKRLsELKAKLEALEEELSEIEDPKGEDEEIPEE 949
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1156-1682 9.70e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 9.70e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1156 RSLLEEERTKNATL-ARELSDLHSKYSVVEKQRPKVQLQERvheifqvdpETEQEITRLKAKLQEMAGKRSGVEKEVEKL 1234
Cdd:COG1196   216 RELKEELKELEAELlLLKLRELEAELEELEAELEELEAELE---------ELEAELAELEAELEELRLELEELELELEEA 286
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1235 LPDLEVLRAQKPTVEykevTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVETKTVS 1314
Cdd:COG1196   287 QAEEYELLAELARLE----QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1315 KEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKP-EEKVVVQEVVVTQKDPKLREEHSRLSG 1393
Cdd:COG1196   363 AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLErLERLEEELEELEEALAELEEEEEEEEE 442
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1394 SLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEVVKLEKDPD 1473
Cdd:COG1196   443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL 522
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1474 LEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDvlQKAKSQEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAR 1553
Cdd:COG1196   523 AGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD--EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAA 600
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1554 EEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQ 1633
Cdd:COG1196   601 VDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE 680
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 156104874 1634 RGQELSRLEAAILREKDQIYEKERTLRDLHAKVSREELSQETQTRETNL 1682
Cdd:COG1196   681 LEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ 729
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
946-1690 1.70e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 1.70e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   946 RTQRPLERLEEkeVVEfyrdpQLEGSLSRVKAQVEEEGK----RRAGLQADLEVAAQKVVQLESKRKTMQpHLLTKEVTQ 1021
Cdd:TIGR02168  183 RTRENLDRLED--ILN-----ELERQLKSLERQAEKAERykelKAELRELELALLVLRLEELREELEELQ-EELKEAEEE 254
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1022 VERdpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLAL--EKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQM 1099
Cdd:TIGR02168  255 LEE---LTAELQELEEKLEELRLEVSELEEEIEELQKELYALanEISRLEQQKQILRERLANLERQLEELEAQLEELESK 331
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1100 -EEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTKNATLARELSDLHs 1178
Cdd:TIGR02168  332 lDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLE- 410
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1179 kysvvekqrpkvQLQERVHEIFQVDPETEQEITRlkAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKPTVEykevtqevv 1258
Cdd:TIGR02168  411 ------------RLEDRRERLQQEIEELLKKLEE--AELKELQAELEELEEELEELQEELERLEEALEELR--------- 467
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1259 rhERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVETKT----VSKEVVRHEKDPVLEKEA---E 1331
Cdd:TIGR02168  468 --EELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSgilgVLSELISVDEGYEAAIEAalgG 545
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1332 RLRQEVREAAQkrrAAEDAVYELQSKRL-------------------LLERRKPEEKVVVQEVVVTQKDPKLRE------ 1386
Cdd:TIGR02168  546 RLQAVVVENLN---AAKKAIAFLKQNELgrvtflpldsikgteiqgnDREILKNIEGFLGVAKDLVKFDPKLRKalsyll 622
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1387 EHSRLSGSLDEEVGRRRQLE-------LEVQQLRAGveeqeGLLSFQEDR--SKKLAVERELRQLTLRIQELEkrpptVQ 1457
Cdd:TIGR02168  623 GGVLVVDDLDNALELAKKLRpgyrivtLDGDLVRPG-----GVITGGSAKtnSSILERRREIEELEEKIEELE-----EK 692
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1458 EKIIMEEVVklekdpDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQidvLQKAKSQEKTIYKEVIRVQKDRV-LEDER 1536
Cdd:TIGR02168  693 IAELEKALA------ELRKELEELEEELEQLRKELEELSRQISALRKD---LARLEAEVEQLEERIAQLSKELTeLEAEI 763
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1537 ARVWEMLNRERTARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEE 1616
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1617 SKLLSQKTESERQKAAQRGQ-----------------ELSRLEAAILREKDQIYEKERTLRDLHAKVSR-EELSQETQTR 1678
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEEleelieeleseleallnERASLEEALALLRSELEELSEELRELESKRSElRRELEELREK 923
                          810
                   ....*....|..
gi 156104874  1679 ETNLSTKISILE 1690
Cdd:TIGR02168  924 LAQLELRLEGLE 935
PTZ00121 PTZ00121
MAEBL; Provisional
879-1662 1.84e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 73.25  E-value: 1.84e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  879 EFARKMLEKKELSEDIRRTHDAKQGSEspaqAGRESEALKAqleEERKRVARVQHELEAQRSQllQLRTQRPLERLEE-K 957
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAED----ARKAEEARKA---EDAKRVEIARKAEDARKAE--EARKAEDAKKAEAaR 1182
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  958 EVVEFYRDPQLEgslsrvkaQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQphllTKEVTQVERDPGLDSQAAQLRI 1037
Cdd:PTZ00121 1183 KAEEVRKAEELR--------KAEDARKAEAARKAEEERKAEEARKAEDAKKAEA----VKKAEEAKKDAEEAKKAEEERN 1250
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1038 QIQQLRGEDAVIsARLEGLKKELLALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEdaarRKQAEEAVAKLQ 1117
Cdd:PTZ00121 1251 NEEIRKFEEARM-AHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEE----AKKADEAKKKAE 1325
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1118 ARIEDLERAISSVEPKVIVKEVKKVEqdpgllqessrlrsllEEERTKNATLARELSDLHSKYSVVEKQRPKvQLQERVH 1197
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAE----------------AEAAADEAEAAEEKAEAAEKKKEEAKKKAD-AAKKKAE 1388
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1198 EIFQVDpeteqeitRLKAKLQEMAGKRSGVEKEVEkllpdlevlrAQKPTVEYKEVTQEVVRHE---RSPEVLREIDRLK 1274
Cdd:PTZ00121 1389 EKKKAD--------EAKKKAEEDKKKADELKKAAA----------AKKKADEAKKKAEEKKKADeakKKAEEAKKADEAK 1450
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1275 AQLNElvnshGRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRHEKdpvlekEAERLRQEVREAAQKRRAAEDAvYEL 1354
Cdd:PTZ00121 1451 KKAEE-----AKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE------EAKKKADEAKKAAEAKKKADEA-KKA 1518
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1355 QSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLA 1434
Cdd:PTZ00121 1519 EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVM 1598
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1435 VERElRQLTLRIQELEKRPptvQEKIIMEEVVKLEkdpDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKS 1514
Cdd:PTZ00121 1599 KLYE-EEKKMKAEEAKKAE---EAKIKAEELKKAE---EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAE 1671
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1515 QEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAREEEARRlreridRAETLGRTWSREESELQRARDQADQEcGR 1594
Cdd:PTZ00121 1672 EDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKK------KAEELKKAEEENKIKAEEAKKEAEED-KK 1744
                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1595 LQQELRALErqkqqqtlqlqEESKLLSQKTESERQKAAQRGQELSRLEAAILREKDQI--YEKERTLRDL 1662
Cdd:PTZ00121 1745 KAEEAKKDE-----------EEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKrrMEVDKKIKDI 1803
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
912-1573 9.70e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.74  E-value: 9.70e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  912 RESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQRPlerleekevvefyrdpQLEGSLSRVKAQVEEEGKRRAGLQA 991
Cdd:COG1196   225 LEAELLLLKLRELEAELEELEAELEELEAELEELEAELA----------------ELEAELEELRLELEELELELEEAQA 288
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  992 DLEVAAQKVVQLESKRKTmqphlltkevtQVERDPGLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVK 1071
Cdd:COG1196   289 EEYELLAELARLEQDIAR-----------LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1072 EKVVVKEVVKveknLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSvepkvivkevkkveqdpgLLQE 1151
Cdd:COG1196   358 AELAEAEEAL----LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEA------------------LLER 415
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1152 SSRLRSLLEEERTKNATLARELSDLHSKYS-----VVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSG 1226
Cdd:COG1196   416 LERLEEELEELEEALAELEEEEEEEEEALEeaaeeEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL 495
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1227 VEKEVEKLLPDLEVLRAQKPTVEYKEVTQEVVRHERSPEVLRE--IDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRE 1304
Cdd:COG1196   496 LLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAalEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT 575
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1305 RAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKD--- 1381
Cdd:COG1196   576 FLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEgeg 655
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1382 --PKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERE-LRQLTLRIQELEKRPPTVQE 1458
Cdd:COG1196   656 gsAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEeRLEEELEEEALEEQLEAERE 735
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1459 KIIMEEVVKLEKDPDLEKSTEALRWDLDQEKTQVTELNRECKNL-QVQIDVLQKAKSQEKTiyKEVIRVQKDrVLEDERA 1537
Cdd:COG1196   736 ELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgPVNLLAIEEYEELEER--YDFLSEQRE-DLEEARE 812
                         650       660       670
                  ....*....|....*....|....*....|....*.
gi 156104874 1538 RvwemlnrertarqareeearrLRERIDRAETLGRT 1573
Cdd:COG1196   813 T---------------------LEEAIEEIDRETRE 827
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
917-1688 2.53e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 66.15  E-value: 2.53e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   917 LKAQLEEERKRVARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQADLEVA 996
Cdd:pfam02463  167 LKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELL 246
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   997 AQKVVQLESKRKTMQPHllTKEVTQVERDPGLDSQaaqlriQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVV- 1075
Cdd:pfam02463  247 RDEQEEIESSKQEIEKE--EEKLAQVLKENKEEEK------EKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKe 318
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1076 -VKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKKVEQDPGLLQESSR 1154
Cdd:pfam02463  319 sEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE 398
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1155 LRSLLEEERTKNATLAR----ELSDLHSKYSVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQemagkrsgvEKE 1230
Cdd:pfam02463  399 LKSEEEKEAQLLLELARqledLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELE---------LKK 469
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1231 VEKLLPDLEVLraqkptveyKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVET 1310
Cdd:pfam02463  470 SEDLLKETQLV---------KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN 540
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1311 KTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHS- 1389
Cdd:pfam02463  541 YKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDk 620
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1390 -RLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEVVKL 1468
Cdd:pfam02463  621 rAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLE 700
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1469 EKDPDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEKTIYKEvIRVQKDRVLEDERARVWEMLNRERT 1548
Cdd:pfam02463  701 IKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEK-SRLKKEEKEEEKSELSLKEKELAEE 779
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1549 ARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKtESER 1628
Cdd:pfam02463  780 REKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEE-ELER 858
                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1629 QKAAQRGQELSRLEAAILREKDQIYEKERTLrDLHAKVSREELSQETQTRETNLSTKISI 1688
Cdd:pfam02463  859 LEEEITKEELLQELLLKEEELEEQKLKDELE-SKEEKEKEEKKELEEESQKLNLLEEKEN 917
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1326-1679 4.33e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 4.33e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1326 LEKEAERLRQEvREAAQKRRAAEDAVYELQSKRLLLERRKpeekvvvqevvvtqkdpkLREEHSRLSGSLDEEVGRRRQL 1405
Cdd:COG1196   198 LERQLEPLERQ-AEKAERYRELKEELKELEAELLLLKLRE------------------LEAELEELEAELEELEAELEEL 258
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1406 ELEVQQLRAGVEEQegllsfqedRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEvvklEKDPDLEKSTEALRWDL 1485
Cdd:COG1196   259 EAELAELEAELEEL---------RLELEELELELEEAQAEEYELLAELARLEQDIARLE----ERRRELEERLEELEEEL 325
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1486 DQEKTQVTELNRECKNLQVQIDVLQKAKSQEKtiykEVIRVQKDRVLEDERARvwemLNRERTARQAREEEARRLRERID 1565
Cdd:COG1196   326 AELEEELEELEEELEELEEELEEAEEELEEAE----AELAEAEEALLEAEAEL----AEAEEELEELAEELLEALRAAAE 397
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1566 RAEtlgrtwsrEESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRGQELSRLEAAI 1645
Cdd:COG1196   398 LAA--------QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
                         330       340       350
                  ....*....|....*....|....*....|....
gi 156104874 1646 LREKDQIYEKERTLRDLHAKVSREELSQETQTRE 1679
Cdd:COG1196   470 EEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1858-1896 5.72e-10

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 56.18  E-value: 5.72e-10
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 156104874  1858 LLEAQAATGGIVDLLSRERYSVHKAMERGLIENTSTQRL 1896
Cdd:pfam00681    1 LLEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
782-1339 9.43e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 9.43e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  782 QIAYKLQAQKRLTQEIQSRERDRATASHLSQALQAALQDYELQADTYRCSLEPTLAVSAPKRPRVAPLQESIQAQEKNLA 861
Cdd:COG1196   240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  862 KAYTEVAAAQQQLLQQLEfarKMLEKKELSEDIRRTHDAKQGSESpAQAGRESEALKAQLEEERKRVARVQHELEAQRSQ 941
Cdd:COG1196   320 ELEEELAELEEELEELEE---ELEELEEELEEAEEELEEAEAELA-EAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  942 LLQLRTQRPLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQ 1021
Cdd:COG1196   396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1022 VERDPGLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEE 1101
Cdd:COG1196   476 EAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVED 555
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1102 DAARRKQAEEAVAKLQARIEDLERAissvepkviVKEVKKVEQDPGLLQESSRLRSLLEEERTKNATLARELSDLHSKYS 1181
Cdd:COG1196   556 DEVAAAAIEYLKAAKAGRATFLPLD---------KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRT 626
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1182 VVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKptvEYKEVTQEVVRHE 1261
Cdd:COG1196   627 LVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE---EELELEEALLAEE 703
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 156104874 1262 rspEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVRE 1339
Cdd:COG1196   704 ---EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1038-1545 7.16e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 61.23  E-value: 7.16e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1038 QIQQLRGEDAVISARLEGLKKELLALEKREVDVKekvvvkevvkveknlEMVKAAQALRLQMEEDAARRKQAEEAVAKLQ 1117
Cdd:PRK03918  208 EINEISSELPELREELEKLEKEVKELEELKEEIE---------------ELEKELESLEGSKRKLEEKIRELEERIEELK 272
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1118 ARIEDLE---RAISSVEPKVIVKEVKKVEQDPgLLQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQRPKVQLQE 1194
Cdd:PRK03918  273 KEIEELEekvKELKELKEKAEEYIKLSEFYEE-YLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELE 351
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1195 RVHEIFQVDPETEQEITRLKAKLQEMAGKRSGveKEVEKLLPDLEVLRAQKPTVEykevtqevvrherspevlREIDRLK 1274
Cdd:PRK03918  352 KRLEELEERHELYEEAKAKKEELERLKKRLTG--LTPEKLEKELEELEKAKEEIE------------------EEISKIT 411
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1275 AQLNELVNSHGRSQEQLIRLQGerdewrrerAKVETKTVSKEVVRHEKDPVLEK---EAERLRQEVREAAQKRRAAEDAV 1351
Cdd:PRK03918  412 ARIGELKKEIKELKKAIEELKK---------AKGKCPVCGRELTEEHRKELLEEytaELKRIEKELKEIEEKERKLRKEL 482
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1352 YELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLR--------EEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLL 1423
Cdd:PRK03918  483 RELEKVLKKESELIKLKELAEQLKELEEKLKKYNleelekkaEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELE 562
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1424 SFQEDRSKKLA-VERELR--------QLTLRIQELEKrpptvqekiIMEEVVKLEKDP----DLEKSTEALRWDLDQEKT 1490
Cdd:PRK03918  563 KKLDELEEELAeLLKELEelgfesveELEERLKELEP---------FYNEYLELKDAEkeleREEKELKKLEEELDKAFE 633
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 156104874 1491 QVTELNRECKNLQVQIDVLQKAKSQEKTIYKEVIRVQKDRVLEDERARVWEMLNR 1545
Cdd:PRK03918  634 ELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKR 688
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
481-1280 1.10e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.46  E-value: 1.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   481 LASELQALKQKLATVQSRLKASAVESLRpsqqapsgsdlANPQAQKLLTQMTRLDGDLGQIERQVLAWARAPLSRPTPLE 560
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEE-----------LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEIS 298
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   561 DLEGRIHSHEgtaQRLQSLGTEKETAQKECEAFLSTRpvgpaaLQLPVALNSVKNKFSDVQVLCSLYGEKAKAAL----D 636
Cdd:TIGR02168  299 RLEQQKQILR---ERLANLERQLEELEAQLEELESKL------DELAEELAELEEKLEELKEELESLEAELEELEaeleE 369
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   637 LERQIQDADRVIRGFEATLV----QEAPIPAEPGALQERVSELQRQRRELLEQQTCVLRlhralKASEHACAALQNNFQE 712
Cdd:TIGR02168  370 LESRLEELEEQLETLRSKVAqlelQIASLNNEIERLEARLERLEDRRERLQQEIEELLK-----KLEEAELKELQAELEE 444
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   713 FCQDLPRQQRQVRALTDRYHAVGDQLDLREKVVQDAALTYQQFKNCKDNLSSWLEHLprsqvrpSDGPSQIAYKLQAQKR 792
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL-------EGFSEGVKALLKNQSG 517
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   793 LT-------QEIQSRERDRATashLSQALQAALQDYELQ-ADTYRcsleptLAVSAPKRP---RVAPLQES------IQA 855
Cdd:TIGR02168  518 LSgilgvlsELISVDEGYEAA---IEAALGGRLQAVVVEnLNAAK------KAIAFLKQNelgRVTFLPLDsikgteIQG 588
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   856 QEKNLAKAYTEVAAAQQQLLQQLEFARKMLE------------------KKELSE---------DIRRTHDAKQGSESPA 908
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddldnalelAKKLRPgyrivtldgDLVRPGGVITGGSAKT 668
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   909 QAG-----RESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEfyRDPQLEGSLSRVKAQVEEEG 983
Cdd:TIGR02168  669 NSSilerrREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR--QISALRKDLARLEAEVEQLE 746
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   984 KRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVErdpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLAL 1063
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE----LEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1064 EKREVdvkekvvvkevvkveknlEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEpkvivkevkkvE 1143
Cdd:TIGR02168  823 RERLE------------------SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE-----------S 873
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1144 QDPGLLQESSRLRSLLEEERTKNATLARELSDLHSKysVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGk 1223
Cdd:TIGR02168  874 ELEALLNERASLEEALALLRSELEELSEELRELESK--RSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS- 950
                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 156104874  1224 rsgvekevekllpdlevlraqkptVEYKEVTQEVVRHERSPEVLR-EIDRLKAQLNEL 1280
Cdd:TIGR02168  951 ------------------------LTLEEAEALENKIEDDEEEARrRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
559-1339 3.28e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 3.28e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   559 LEDLEGRIHSHEGTAQRLQSLGTEKETAQKECEAFLStrpvgpaalQLPVALNSVKNKFSDVQvlcSLYGEKAKAALDLE 638
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLE---------ELRLEVSELEEEIEELQ---KELYALANEISRLE 301
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   639 RQIQDADRVIRGFEATLVQeapipaepgaLQERVSELQRQRRELLEQqtcvlrlhraLKASEHACAALQNNFQEFCQDLP 718
Cdd:TIGR02168  302 QQKQILRERLANLERQLEE----------LEAQLEELESKLDELAEE----------LAELEEKLEELKEELESLEAELE 361
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   719 RQQRQVRALTDRYHAVGDQLdlrEKVVQDAALTYQQFKNCKDNLSSWLEHLPRSQVRpsdgpsqiayklqaQKRLTQEIQ 798
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQL---ETLRSKVAQLELQIASLNNEIERLEARLERLEDR--------------RERLQQEIE 424
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   799 SrerdratasHLSQALQAALQDYELQADTyrcsLEPTLAVSAPKRPRVAPLQESIQAQEKNLAKAYTEVAAAQQQLLQQL 878
Cdd:TIGR02168  425 E---------LLKKLEEAELKELQAELEE----LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL 491
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   879 EFARKMLEKKE-LSEDIRRThdAKQGSESPAQAGRESEALKAQLEEER---------------KRVARVQHELEAQRSQL 942
Cdd:TIGR02168  492 DSLERLQENLEgFSEGVKAL--LKNQSGLSGILGVLSELISVDEGYEAaieaalggrlqavvvENLNAAKKAIAFLKQNE 569
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   943 LQLRTQRPLERLE--EKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQA---------DLEVAAQKVVQLESKRK--T 1009
Cdd:TIGR02168  570 LGRVTFLPLDSIKgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYllggvlvvdDLDNALELAKKLRPGYRivT 649
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1010 MQPHLLTKEVTQVERDPGLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVVKEVVKVEKNLEMV 1089
Cdd:TIGR02168  650 LDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQIS 729
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1090 ---KAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTKN 1166
Cdd:TIGR02168  730 alrKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR 809
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1167 ATLARELSDLHSKYSVVEkqrpkvQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKP 1246
Cdd:TIGR02168  810 AELTLLNEEAANLRERLE------SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1247 TVEYKEVTQEVVRHERSP---EVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWR---RERAKVETKTVSKEVVRH 1320
Cdd:TIGR02168  884 SLEEALALLRSELEELSEelrELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQerlSEEYSLTLEEAEALENKI 963
                          810       820
                   ....*....|....*....|
gi 156104874  1321 EKDP-VLEKEAERLRQEVRE 1339
Cdd:TIGR02168  964 EDDEeEARRRLKRLENKIKE 983
PLEC smart00250
Plectin repeat;
1894-1931 8.57e-08

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 49.79  E-value: 8.57e-08
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 156104874   1894 QRLLNAQKAFTGIEDPVTKKRLSVGEAVQKGWMPRESV 1931
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
SPEC cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ...
228-415 1.21e-07

Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here


Pssm-ID: 238103 [Multi-domain]  Cd Length: 213  Bit Score: 54.37  E-value: 1.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  228 LYTHLQGCTRQLSALAEQQRRILQQDwsDLMADPAGVRREYEHFK--QHELLSQEQSVNQLEDDGERMVELRHPAVGPIQ 305
Cdd:cd00176     1 KLQQFLRDADELEAWLSEKEELLSST--DYGDDLESVEALLKKHEalEAELAAHEERVEALNELGEQLIEEGHPDAEEIQ 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  306 AHQEALKMEWQNFLNLCICQETQLQHVEDYRRFQEEADSVSQTLAKLNSNLDakySPAPGGPPGAPTELLQQLEAEEKRL 385
Cdd:cd00176    79 ERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEEKEAALA---SEDLGKDLESVEELLKKHKELEEEL 155
                         170       180       190
                  ....*....|....*....|....*....|
gi 156104874  386 avtERATGDLQRRSRDVAPLPQRRNPPQQP 415
Cdd:cd00176   156 ---EAHEPRLKSLNELAEELLEEGHPDADE 182
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1935-1972 1.47e-07

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 49.25  E-value: 1.47e-07
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 156104874  1935 LQVQHLTGGLIDPKRTGRIPIQQALLSGMISEELAQLL 1972
Cdd:pfam00681    2 LEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
1148-1411 1.63e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 56.67  E-value: 1.63e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1148 LLQESSRLRSLLEEERTKNATLARELSDLHSKYSVV---EKQRPKVQLQERVHEIFQVdpeTEQEITRLKAKLQEMAGKR 1224
Cdd:pfam17380  308 KAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAmerERELERIRQEERKRELERI---RQEEIAMEISRMRELERLQ 384
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1225 SGVEKEVEKLLPDLEVLRAQK-------PTVEYKEVTQEVVRHERSPEVLREIDRLKAQ----LNELVNSHGRSQEQLIR 1293
Cdd:pfam17380  385 MERQQKNERVRQELEAARKVKileeerqRKIQQQKVEMEQIRAEQEEARQREVRRLEEErareMERVRLEEQERQQQVER 464
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1294 LQGERDEWRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAE-------DAVYELQSKRLLLERRKP 1366
Cdd:pfam17380  465 LRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEkemeerqKAIYEEERRREAEEERRK 544
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 156104874  1367 EEKVVVQEVVVTQKDpKLREEHSRLSGSLDEEVGRRRQLELEVQQ 1411
Cdd:pfam17380  545 QQEMEERRRIQEQMR-KATEERSRLEAMEREREMMRQIVESEKAR 588
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
914-1470 2.92e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.84  E-value: 2.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  914 SEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQ-----RPLERLEE-KEVVEFYR--DPQLEGSLSRVKAQVEEEGKR 985
Cdd:PRK03918  188 TENIEELIKEKEKELEEVLREINEISSELPELREElekleKEVKELEElKEEIEELEkeLESLEGSKRKLEEKIRELEER 267
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  986 RAGLQADLEVAAQKVVQLESKRKTMQPHL----LTKEVTQVERDpgLDSQAAQLRIQIQQLRGEDAVIS---ARLEGLKK 1058
Cdd:PRK03918  268 IEELKKEIEELEEKVKELKELKEKAEEYIklseFYEEYLDELRE--IEKRLSRLEEEINGIEERIKELEekeERLEELKK 345
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1059 ELLALEKREVDVKEKVVVkevvkveknLEMVKAaqalrLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKE 1138
Cdd:PRK03918  346 KLKELEKRLEELEERHEL---------YEEAKA-----KKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKIT 411
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1139 VKKVeqdpGLLQESSRLRSLLEE---ERTKNATLARELSDLHSKYSVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKA 1215
Cdd:PRK03918  412 ARIG----ELKKEIKELKKAIEElkkAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEK 487
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1216 KLQ---EMAGKRSGVE--KEVEKLLPDLEVLRAQKPTVEYKEVtqevvrHERSPEVLREIDRLKAQLNELVNSHGRSQEq 1290
Cdd:PRK03918  488 VLKkesELIKLKELAEqlKELEEKLKKYNLEELEKKAEEYEKL------KEKLIKLKGEIKSLKKELEKLEELKKKLAE- 560
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1291 lirLQGERDEWRRERAKVETKTvskevvrHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKrllLERRKpeekv 1370
Cdd:PRK03918  561 ---LEKKLDELEEELAELLKEL-------EELGFESVEELEERLKELEPFYNEYLELKDAEKELERE---EKELK----- 622
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1371 vvqevvvtqkdpKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEgllsFQEDRSKKLAVERELRQLTLRIQELE 1450
Cdd:PRK03918  623 ------------KLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEE----YEELREEYLELSRELAGLRAELEELE 686
                         570       580
                  ....*....|....*....|..
gi 156104874 1451 KRPPTVQEKI--IMEEVVKLEK 1470
Cdd:PRK03918  687 KRREEIKKTLekLKEELEEREK 708
PTZ00121 PTZ00121
MAEBL; Provisional
1087-1679 6.54e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.15  E-value: 6.54e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1087 EMVKAAQALRLQMEEDAARRKQAEEAVAKLQAR-IEDLERAIssvepKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTK 1165
Cdd:PTZ00121 1144 EARKAEDAKRVEIARKAEDARKAEEARKAEDAKkAEAARKAE-----EVRKAEELRKAEDARKAEAARKAEEERKAEEAR 1218
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1166 NATLARELSDLHSkysvVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQK 1245
Cdd:PTZ00121 1219 KAEDAKKAEAVKK----AEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADE 1294
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1246 PtveykevtqevvrheRSPEVLREIDRLKAQLNElvnshGRSQEQLiRLQGERDEWRRERAKVETKTVSKevvrheKDPV 1325
Cdd:PTZ00121 1295 A---------------KKAEEKKKADEAKKKAEE-----AKKADEA-KKKAEEAKKKADAAKKKAEEAKK------AAEA 1347
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1326 LEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEhsrlsgsldeeVGRRRQL 1405
Cdd:PTZ00121 1348 AKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADE-----------LKKAAAA 1416
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1406 ELEVQQLRAGVEEQEgllsfQEDRSKKLAVERElrqltlRIQELEKRpptVQEKIIMEEVVKleKDPDLEKSTEALRwdL 1485
Cdd:PTZ00121 1417 KKKADEAKKKAEEKK-----KADEAKKKAEEAK------KADEAKKK---AEEAKKAEEAKK--KAEEAKKADEAKK--K 1478
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1486 DQEKTQVTELNRECKNLQVQIDVLQKaKSQEKTIYKEVIRVQKDRVLEDERARvwemlNRERTARQAREEEARRLRERID 1565
Cdd:PTZ00121 1479 AEEAKKADEAKKKAEEAKKKADEAKK-AAEAKKKADEAKKAEEAKKADEAKKA-----EEAKKADEAKKAEEKKKADELK 1552
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1566 RAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLL----SQKTESERQKAAQ-------- 1633
Cdd:PTZ00121 1553 KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMkaeeAKKAEEAKIKAEElkkaeeek 1632
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*..
gi 156104874 1634 -RGQELSRLEAAILREKDQIYEKERTLRDLHAKVSREELSQETQTRE 1679
Cdd:PTZ00121 1633 kKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEE 1679
PLEC smart00250
Plectin repeat;
1856-1889 6.58e-07

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 47.48  E-value: 6.58e-07
                            10        20        30
                    ....*....|....*....|....*....|....
gi 156104874   1856 QKLLEAQAATGGIVDLLSRERYSVHKAMERGLIE 1889
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLID 34
PTZ00121 PTZ00121
MAEBL; Provisional
850-1402 1.07e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.38  E-value: 1.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  850 QESIQAQEKNLAKAYTEVAAAQQQLLQQLEFARKMLEKKElSEDIRRTHDAKQGSES-PAQAGRESEALKAQLEEERK-R 927
Cdd:PTZ00121 1240 EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARK-ADELKKAEEKKKADEAkKAEEKKKADEAKKKAEEAKKaD 1318
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  928 VARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLEGSLSRVKA--QVEEEGKRRAglqADLEVAAQKVVQLES 1005
Cdd:PTZ00121 1319 EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAaeKKKEEAKKKA---DAAKKKAEEKKKADE 1395
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1006 KRKTMQPHllTKEVTQVERDPGLDSQAAQLRIQIQQLRGED-----AVISARLEGLKKELLALEKREVDVKEKVVVKEVV 1080
Cdd:PTZ00121 1396 AKKKAEED--KKKADELKKAAAAKKKADEAKKKAEEKKKADeakkkAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD 1473
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1081 KVEKNLEMVKAAQALRLQMEEdaaRRKQAEEAVAKLQA--RIEDLERAISSVEPKVIVKEVKKVEQDpgllqessRLRSL 1158
Cdd:PTZ00121 1474 EAKKKAEEAKKADEAKKKAEE---AKKKADEAKKAAEAkkKADEAKKAEEAKKADEAKKAEEAKKAD--------EAKKA 1542
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1159 LEEERTKNATLARELSDLHSKYSVVEKQRP---KVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLL 1235
Cdd:PTZ00121 1543 EEKKKADELKKAEELKKAEEKKKAEEAKKAeedKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA 1622
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1236 PDLEVLRAQKPTVEY--KEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRlqGERDEWRRERA---KVET 1310
Cdd:PTZ00121 1623 EELKKAEEEKKKVEQlkKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKK--AEEDEKKAAEAlkkEAEE 1700
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1311 KTVSKEVVRHEKDPVleKEAERLRQEvrEAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHSR 1390
Cdd:PTZ00121 1701 AKKAEELKKKEAEEK--KKAEELKKA--EEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKE 1776
                         570
                  ....*....|..
gi 156104874 1391 LSGSLDEEVGRR 1402
Cdd:PTZ00121 1777 KEAVIEEELDEE 1788
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1191-1666 1.69e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.53  E-value: 1.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1191 QLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEV---EKLLPDLEVLRAQKPTVEYKEVTQEvvrhERSPEVL 1267
Cdd:PRK03918  190 NIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVkelEELKEEIEELEKELESLEGSKRKLE----EKIRELE 265
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1268 REIDRLKAQLNELVNSHGRSQE------QLIRLQGERDEWRRERAKVEtKTVSKEVVRHEKDPVLEKEAERLRQEVREAA 1341
Cdd:PRK03918  266 ERIEELKKEIEELEEKVKELKElkekaeEYIKLSEFYEEYLDELREIE-KRLSRLEEEINGIEERIKELEEKEERLEELK 344
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1342 QKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDP---------KLREEHSRLSGSLDEEVGRRRQLELEVQQL 1412
Cdd:PRK03918  345 KKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTpeklekeleELEKAKEEIEEEISKITARIGELKKEIKEL 424
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1413 RAGVEEQE---------GLLSFQEDRSKKLA--------VERELRQLTLRIQELEKRPPTVQEKIIME-EVVKLEKDPD- 1473
Cdd:PRK03918  425 KKAIEELKkakgkcpvcGRELTEEHRKELLEeytaelkrIEKELKEIEEKERKLRKELRELEKVLKKEsELIKLKELAEq 504
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1474 ---LEKSTEALRW-DLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEKTIYKEVIRVQKD-RVLEDERARVwemlnrERT 1548
Cdd:PRK03918  505 lkeLEEKLKKYNLeELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKlDELEEELAEL------LKE 578
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1549 ARQAREEEARRLRERIDRAETLGRTWSR---EESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTE 1625
Cdd:PRK03918  579 LEELGFESVEELEERLKELEPFYNEYLElkdAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE 658
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*
gi 156104874 1626 SERQKAAQR----GQELSRLEAAILREKDQIYEKERTLRDLHAKV 1666
Cdd:PRK03918  659 EEYEELREEylelSRELAGLRAELEELEKRREEIKKTLEKLKEEL 703
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
1153-1680 2.26e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.20  E-value: 2.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1153 SRLRSLLEEERTKNATLARELSDLHSKYSVV--EKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKE 1230
Cdd:pfam15921  299 SQLEIIQEQARNQNSMYMRQLSDLESTVSQLrsELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQ 378
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1231 VEKLLPDLEvlRAQKPTVEYKEVTQEVVRHERSPEVlrEIDRLKAQLNELVNSHGRSQEQLIRLQGE-RDEWRRERAKVE 1309
Cdd:pfam15921  379 LQKLLADLH--KREKELSLEKEQNKRLWDRDTGNSI--TIDHLRRELDDRNMEVQRLEALLKAMKSEcQGQMERQMAAIQ 454
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1310 TKTVSKEVVRhEKDPVLEKEAERLRQevreaaqkrraaedAVYELQSKRLLLERRKpeekvvvqeVVVTQKDPKLREEHS 1389
Cdd:pfam15921  455 GKNESLEKVS-SLTAQLESTKEMLRK--------------VVEELTAKKMTLESSE---------RTVSDLTASLQEKER 510
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1390 RLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQ-EDRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEVVKL 1468
Cdd:pfam15921  511 AIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQtECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQV 590
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1469 EKdPDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEKTIYKEVIRVQKDrvLEDERArvwEMLNRERT 1548
Cdd:pfam15921  591 EK-AQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKD--IKQERD---QLLNEVKT 664
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1549 ARQAREEEArrlreriDRAETLGRTWSREESELQRARDQADQECGRLQQElraLERQKQQQTLQLQEESKLLSQKTESER 1628
Cdd:pfam15921  665 SRNELNSLS-------EDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSE---LEQTRNTLKSMEGSDGHAMKVAMGMQK 734
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 156104874  1629 QKAAQRGQelsrLEAaiLREKDQIYEKERTLRDLHAKVSREE---LSQETQTRET 1680
Cdd:pfam15921  735 QITAKRGQ----IDA--LQSKIQFLEEAMTNANKEKHFLKEEknkLSQELSTVAT 783
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
1190-1517 3.38e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.43  E-value: 3.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1190 VQLQERVHEIFQVDPETEQEITRLKAKLQEMAgkrsgveKEVEKLLPDLEVLRAQKPTVEyKEVTQEVVRHERSPEVLRE 1269
Cdd:pfam17380  278 VQHQKAVSERQQQEKFEKMEQERLRQEKEEKA-------REVERRRKLEEAEKARQAEMD-RQAAIYAEQERMAMERERE 349
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1270 IDRLKAQLNELVNSHGRSQE---------QLIRLQGERDEwRRERakvetktVSKEVVRHEKDPVLEKEAERLRQEVREA 1340
Cdd:pfam17380  350 LERIRQEERKRELERIRQEEiameisrmrELERLQMERQQ-KNER-------VRQELEAARKVKILEEERQRKIQQQKVE 421
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1341 AQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREehsrlsgslDEEVGRRRQLELEVQQL-RAGVEEQ 1419
Cdd:pfam17380  422 MEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQ---------QEEERKRKKLELEKEKRdRKRAEEQ 492
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1420 EGLLSFQEDRSKKLAVERELRQLTLRIQELEKRPPTVQEKiimEEVVKLEKDPDLEKSTEAlRWDLDQEKTQVTELNREC 1499
Cdd:pfam17380  493 RRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEE---ERRREAEEERRKQQEMEE-RRRIQEQMRKATEERSRL 568
                          330
                   ....*....|....*...
gi 156104874  1500 KNLQVQIDVLQKAKSQEK 1517
Cdd:pfam17380  569 EAMEREREMMRQIVESEK 586
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
629-1451 4.91e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.99  E-value: 4.91e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   629 EKAKAALDLERQIQDADRVIRGFEATLVQeapIPAEPGALQERVSELQRQRRELLEqqtcvlrlhRALKASEHACAALQN 708
Cdd:TIGR02169  227 ELLKEKEALERQKEAIERQLASLEEELEK---LTEEISELEKRLEEIEQLLEELNK---------KIKDLGEEEQLRVKE 294
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   709 NFQEFCQDLPRQQRQVRALTDRyhavgdqldlrekvVQDAALTYQQFKNCKDNLSSWLEHLPRS----QVRPSDGPSQIA 784
Cdd:TIGR02169  295 KIGELEAEIASLERSIAEKERE--------------LEDAEERLAKLEAEIDKLLAEIEELEREieeeRKRRDKLTEEYA 360
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   785 YKLQAQKRLTQEIQSRERDRATASHLSQALQAALQDYELQADTYRCSLEPTLAVSAPKRPRVAPLQESIQAQEKNLAKAY 864
Cdd:TIGR02169  361 ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELE 440
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   865 TEVaaaqqqllqqlEFARKMLEKKElsedirrtHDAKQGSESPAQAGRESEALKA---QLEEERKRVARVQHELEAQRSQ 941
Cdd:TIGR02169  441 EEK-----------EDKALEIKKQE--------WKLEQLAADLSKYEQELYDLKEeydRVEKELSKLQRELAEAEAQARA 501
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   942 LLQlrtqrplERLEEKEVVEFyrdpqLEGSLSRVKAQVEEEGKRRAGLQADLEVA---------------AQKVVQLESK 1006
Cdd:TIGR02169  502 SEE-------RVRGGRAVEEV-----LKASIQGVHGTVAQLGSVGERYATAIEVAagnrlnnvvveddavAKEAIELLKR 569
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1007 RK----TMQPhlLTKeVTQVERDPGLDSQAAQLRIQIQQLRGED----AVISARLEGLKKELLALEKREVDVKEKVVVKE 1078
Cdd:TIGR02169  570 RKagraTFLP--LNK-MRDERRDLSILSEDGVIGFAVDLVEFDPkyepAFKYVFGDTLVVEDIEAARRLMGKYRMVTLEG 646
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1079 VVKVEKNLeMVKAAQALRlqmeEDAARRKQAEEAVAKLQARIEDLERAISSvepkvivkevkkveqdpgLLQESSRLRSL 1158
Cdd:TIGR02169  647 ELFEKSGA-MTGGSRAPR----GGILFSRSEPAELQRLRERLEGLKRELSS------------------LQSELRRIENR 703
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1159 LEEERTKNATLARELSDLHSKYSVVEKQRPKV-----QLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEK 1233
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLkerleELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALND 783
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1234 LLPDLEVLRAQKPTVEYKEVTQEVVRHErspEVLREIDR-------LKAQLNELVNShgrSQEQLIRLQGERDEWRRERA 1306
Cdd:TIGR02169  784 LEARLSHSRIPEIQAELSKLEEEVSRIE---ARLREIEQklnrltlEKEYLEKEIQE---LQEQRIDLKEQIKSIEKEIE 857
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1307 -----KVETKTVSKEVVRHEKDpvLEKEAERLRQEVREAAQKRRAAEDAVYELQS----KRLLLERRKPEEKVVVQEVVV 1377
Cdd:TIGR02169  858 nlngkKEELEEELEELEAALRD--LESRLGDLKKERDELEAQLRELERKIEELEAqiekKRKRLSELKAKLEALEEELSE 935
                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 156104874  1378 TQKDPKLREEHSRLSGSLDEEVGRRRQLELEVQQL-----RAGVEEQEGLLSFQEDRSKKLAVERELRQLTLRIQELEK 1451
Cdd:TIGR02169  936 IEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALepvnmLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
666-1295 5.14e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 51.89  E-value: 5.14e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   666 GALQERVSELQRQRRELLEQQTCVLRLHRALKASEHACAALQNNFQEFcQDLPRQQRQVRALTDRYHAVGDQLDLREKVV 745
Cdd:TIGR00618  263 KQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQ-RIHTELQSKMRSRAKLLMKRAAHVKQQSSIE 341
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   746 QDAALTYQQFKNCKDNlsswlehlprsqVRPSDGPSQIAYKLQAQKRLTQEIQSRERDRATASHLSQALQAALqdyeLQA 825
Cdd:TIGR00618  342 EQRRLLQTLHSQEIHI------------RDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKEL----DIL 405
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   826 DTYRCSLEPTLAVSAPKRPRVAPLQESIQAQEKNLAKAYTEVAAAQQQLLQQLEFARKMLEKkeLSEDIRRTHDAKQGSE 905
Cdd:TIGR00618  406 QREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQS--LKEREQQLQTKEQIHL 483
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   906 SPAQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLR-TQRPLERLEekevvefYRDPQLEGSLSRVKAQVEEEGK 984
Cdd:TIGR00618  484 QETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGpLTRRMQRGE-------QTYAQLETSEEDVYHQLTSERK 556
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   985 RRAGLQADLEVAAQKVVQLESKRKTMQPHLltkEVTQVERDPGLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALE 1064
Cdd:TIGR00618  557 QRASLKEQMQEIQQSFSILTQCDNRSKEDI---PNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLH 633
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1065 KREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKKVEq 1144
Cdd:TIGR00618  634 LQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETH- 712
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1145 dpglLQESSRLRSLLEE-ERTKNATLARELSDLHSKYSVVEKQRPKvQLQERVHEIFQVDPETEQEITRLkAKLQEMAGK 1223
Cdd:TIGR00618  713 ----IEEYDREFNEIENaSSSLGSDLAAREDALNQSLKELMHQART-VLKARTEAHFNNNEEVTAALQTG-AELSHLAAE 786
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 156104874  1224 RSGVEKEVEKLLPDLEVLRAQ-----KPTVEYKEVTQEVVRHERSpEVLREIDRLKAQLNELVNSHGRSQEQLIRLQ 1295
Cdd:TIGR00618  787 IQFFNRLREEDTHLLKTLEAEigqeiPSDEDILNLQCETLVQEEE-QFLSRLEEKSATLGEITHQLLKYEECSKQLA 862
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
1109-1689 5.19e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 51.89  E-value: 5.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1109 AEEAVAKLQARIEDLERAISSVEPKVIVKEVKKV--EQDPGLLQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQ 1186
Cdd:TIGR00618  210 TPCMPDTYHERKQVLEKELKHLREALQQTQQSHAylTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRA 289
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1187 RPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGV------EKEVEKLLPDLEVLRAQKPTVEyKEVTQEVVRH 1260
Cdd:TIGR00618  290 RKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRaahvkqQSSIEEQRRLLQTLHSQEIHIR-DAHEVATSIR 368
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1261 ERSPEVLREIDRLKAQ------LNELVNSHGRSQEQLIRLQG-------ERDEWRRERAKVETKTVSKEVVRHEKDPVLE 1327
Cdd:TIGR00618  369 EISCQQHTLTQHIHTLqqqkttLTQKLQSLCKELDILQREQAtidtrtsAFRDLQGQLAHAKKQQELQQRYAELCAAAIT 448
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1328 KEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREE-------HSRLSGSLDEEVG 1400
Cdd:TIGR00618  449 CTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGscihpnpARQDIDNPGPLTR 528
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1401 RRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAverelRQLTLRIQELEKRPPTVQE-KIIMEEVVKLEKD--PDLEKS 1477
Cdd:TIGR00618  529 RMQRGEQTYAQLETSEEDVYHQLTSERKQRASLK-----EQMQEIQQSFSILTQCDNRsKEDIPNLQNITVRlqDLTEKL 603
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1478 TEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEK----------TIYKEVIRVQKDRVLEDErARVWEMLNRER 1547
Cdd:TIGR00618  604 SEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALkltalhalqlTLTQERVREHALSIRVLP-KELLASRQLAL 682
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1548 TARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESE 1627
Cdd:TIGR00618  683 QKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEA 762
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 156104874  1628 RQKAA-------QRGQELSRLEAAILREKDQIYEKERTLRDLHAKVSRE--------ELSQET-QTRETNLSTKISIL 1689
Cdd:TIGR00618  763 HFNNNeevtaalQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEipsdedilNLQCETlVQEEEQFLSRLEEK 840
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
879-1422 7.11e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.22  E-value: 7.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  879 EFARKMLEKKELSEDIRRTHDAKQGSESPAQagrESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQRP-----LER 953
Cdd:PRK03918  201 ELEEVLREINEISSELPELREELEKLEKEVK---ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEelkkeIEE 277
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  954 LEEK---------------EVVEFYRdpQLEGSLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPhlLTKE 1018
Cdd:PRK03918  278 LEEKvkelkelkekaeeyiKLSEFYE--EYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKE--LEKR 353
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1019 VTQVERDPGLDSQAAQLRIQIQQLRGEDAVISarLEGLKKELLALEKREVDVKEKVVVKEVVKVeknlEMVKAAQALRLQ 1098
Cdd:PRK03918  354 LEELEERHELYEEAKAKKEELERLKKRLTGLT--PEKLEKELEELEKAKEEIEEEISKITARIG----ELKKEIKELKKA 427
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1099 MEE-DAARRK-----------QAEEAVAKLQARIEDLERAISSVEPKVIVkevkkveqdpgLLQESSRLRSLLEEERT-- 1164
Cdd:PRK03918  428 IEElKKAKGKcpvcgrelteeHRKELLEEYTAELKRIEKELKEIEEKERK-----------LRKELRELEKVLKKESEli 496
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1165 KNATLARELSDLHSKYSVVEKQRPKvqlqervheifqvdpETEQEITRLKAKLQEMAGKRSGVEKEVEKllpdLEVLRAQ 1244
Cdd:PRK03918  497 KLKELAEQLKELEEKLKKYNLEELE---------------KKAEEYEKLKEKLIKLKGEIKSLKKELEK----LEELKKK 557
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1245 KPTVEYKEVTQEvvrhERSPEVLREIDRLKAQLNELVNSHGRSQEQL----IRLQGERDEWRRERAKVEtKTVSKEVVRH 1320
Cdd:PRK03918  558 LAELEKKLDELE----EELAELLKELEELGFESVEELEERLKELEPFyneyLELKDAEKELEREEKELK-KLEEELDKAF 632
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1321 EKDPVLEKEAERLRQEVREAaqKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVvtqkdpKLREEHSRLSGSLDEEVG 1400
Cdd:PRK03918  633 EELAETEKRLEELRKELEEL--EKKYSEEEYEELREEYLELSRELAGLRAELEELE------KRREEIKKTLEKLKEELE 704
                         570       580
                  ....*....|....*....|..
gi 156104874 1401 RRRQLELEVQQLRAGVEEQEGL 1422
Cdd:PRK03918  705 EREKAKKELEKLEKALERVEEL 726
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
629-1132 8.94e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.09  E-value: 8.94e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  629 EKAKAALDLERQIQDADRVIRGFEATLVQEApipAEPGALQERVSELQRQRRELLEQqtcVLRLHRALKASEHACAALQN 708
Cdd:COG1196   243 ELEAELEELEAELEELEAELAELEAELEELR---LELEELELELEEAQAEEYELLAE---LARLEQDIARLEERRRELEE 316
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  709 NFQEFCQDLPRQQRQVRALTDRYHAVGDQLDLREKVVQDAALTYQQFKN-----------CKDNLSSWLEHLPRSQVRPS 777
Cdd:COG1196   317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEalleaeaelaeAEEELEELAEELLEALRAAA 396
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  778 DGPSQIAYKLQAQKRLTQEIQSRERDRATASHLSQALQAALQDYELQADTYRCSLEPTLAVSAPKRPRVAPLQESIQAQE 857
Cdd:COG1196   397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  858 KNLAKAYTEVAAAQQQLLQQLEFARKM---------LEKKELSEDIRRTHDAKQGSESPAQAGRESEALKAQLEEERKRV 928
Cdd:COG1196   477 AALAELLEELAEAAARLLLLLEAEADYegflegvkaALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD 556
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  929 ARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLEGSLSR-VKAQVEEEGKRRAGLQADLEVAAQKVVQLESKR 1007
Cdd:COG1196   557 EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDlVASDLREADARYYVLGDTLLGRTLVAARLEAAL 636
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1008 KTMQPHLLTKEVTQVERDPGLDSQA-----------AQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVV 1076
Cdd:COG1196   637 RRAVTLAGRLREVTLEGEGGSAGGSltggsrrellaALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 156104874 1077 KEVVKVEKNLEMVKAAQALRLQME---------EDAARRKQAEEAVAKLQARIEDLERAISSVEP 1132
Cdd:COG1196   717 LEEELEEEALEEQLEAEREELLEElleeeelleEEALEELPEPPDLEELERELERLEREIEALGP 781
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1153-1365 2.63e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1153 SRLRSLLEEERTKNATL------ARELSDLHSKYSVVEKQRPKVQLQERVHEIFQVdpetEQEITRLKAKLQEMAGKRSG 1226
Cdd:COG4913   238 ERAHEALEDAREQIELLepirelAERYAAARERLAELEYLRAALRLWFAQRRLELL----EAELEELRAELARLEAELER 313
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1227 VEKEVEKLLPDLEVLRAQKPTVEYKEVTQevvrherspeVLREIDRLKAQLNELVNSHGRSQEQLIRLQ----GERDEWR 1302
Cdd:COG4913   314 LEARLDALREELDELEAQIRGNGGDRLEQ----------LEREIERLERELEERERRRARLEALLAALGlplpASAEEFA 383
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 156104874 1303 RERAKVetktvskevvrHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRK 1365
Cdd:COG4913   384 ALRAEA-----------AALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRK 435
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
678-1060 3.46e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.18  E-value: 3.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  678 QRRELLEQqtcVLRLHRALKASEHACAALQNNFQEFCQDLPRQQRQVRALTDRYHAVGDQLDLrekvVQDAALTYQQFKN 757
Cdd:COG3096   279 ERRELSER---ALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNL----VQTALRQQEKIER 351
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  758 CKDNLSSwlehlprsqvrpsdgpsqIAYKLQAQKRLTQEIQSRERDRATASHLSQA----LQAALQDYE----------- 822
Cdd:COG3096   352 YQEDLEE------------------LTERLEEQEEVVEEAAEQLAEAEARLEAAEEevdsLKSQLADYQqaldvqqtrai 413
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  823 -----LQA--DTYRCSLEPTLAVSApkrprVAPLQESIQAQEKNLakayTEVAAAQQQLLQQLEFARKMLEKK-ELSEDI 894
Cdd:COG3096   414 qyqqaVQAleKARALCGLPDLTPEN-----AEDYLAAFRAKEQQA----TEEVLELEQKLSVADAARRQFEKAyELVCKI 484
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  895 ------RRTHDA-----KQGSESPAQAGREsEALKAQLEEERKRVARvQHELEAQRSQLLQlRTQRPLERLEEKEVVEfy 963
Cdd:COG3096   485 ageverSQAWQTarellRRYRSQQALAQRL-QQLRAQLAELEQRLRQ-QQNAERLLEEFCQ-RIGQQLDAAEELEELL-- 559
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  964 rdPQLEGSLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESK----------------------------RKTMQpHLL 1015
Cdd:COG3096   560 --AELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARapawlaaqdalerlreqsgealadsqevTAAMQ-QLL 636
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 156104874 1016 TKEV-TQVERDPgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKEL 1060
Cdd:COG3096   637 EREReATVERDE-LAARKQALESQIERLSQPGGAEDPRLLALAERL 681
SPEC cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ...
156-330 8.11e-05

Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here


Pssm-ID: 238103 [Multi-domain]  Cd Length: 213  Bit Score: 45.90  E-value: 8.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  156 LEQKQKQVCAGQYGPGMAELEQQIAEHNILQKEIDAY----------GQQLRSLVGPDAATIR-------SQYRDLLKAA 218
Cdd:cd00176    16 LSEKEELLSSTDYGDDLESVEALLKKHEALEAELAAHeervealnelGEQLIEEGHPDAEEIQerleelnQRWEELRELA 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  219 SWRGQSLG---SLYTHLQGCTRQLSALAEQQRRILQQDWSDlmaDPAGVRREYEHFK--QHELLSQEQSVNQLEDDGERM 293
Cdd:cd00176    96 EERRQRLEealDLQQFFRDADDLEQWLEEKEAALASEDLGK---DLESVEELLKKHKelEEELEAHEPRLKSLNELAEEL 172
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 156104874  294 VELRHPAVGP-IQAHQEALKMEWQNFLNLCICQETQLQ 330
Cdd:cd00176   173 LEEGHPDADEeIEEKLEELNERWEELLELAEERQKKLE 210
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1033-1530 8.63e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 8.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1033 AQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVVKEVVKveknlEMVKAAQALRLQMEEDAARRKQAEEA 1112
Cdd:PRK03918  241 EELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELK-----EKAEEYIKLSEFYEEYLDELREIEKR 315
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1113 VAKLQARIEDLERAISSVEPKVIVKEVKKVEQDpGLLQESSRLrslleEERTKNATLARELSDLHSKYSVVEKQRPKVQL 1192
Cdd:PRK03918  316 LSRLEEEINGIEERIKELEEKEERLEELKKKLK-ELEKRLEEL-----EERHELYEEAKAKKEELERLKKRLTGLTPEKL 389
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1193 QERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKllpdLEVLRAQKPTVEyKEVTQEvVRHERSPEVLREIDR 1272
Cdd:PRK03918  390 EKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE----LKKAKGKCPVCG-RELTEE-HRKELLEEYTAELKR 463
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1273 LKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRHEKDPVLEK------EAERLRQEVREAAQKRRA 1346
Cdd:PRK03918  464 IEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEElekkaeEYEKLKEKLIKLKGEIKS 543
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1347 AEDAV---YELQSKRLLLERRKPEEKVVVQEVVVtqkdpKLREEHSRLSGSLDEEVGR-----RRQLELE--VQQLRAGV 1416
Cdd:PRK03918  544 LKKELeklEELKKKLAELEKKLDELEEELAELLK-----ELEELGFESVEELEERLKElepfyNEYLELKdaEKELEREE 618
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1417 EEQEGLLSFQEDRSKKLA-VERELRQLTLRIQELEKRPPTVQEKIIMEEVVKLEKDpdleksTEALRWDLDQEKTQVTEL 1495
Cdd:PRK03918  619 KELKKLEEELDKAFEELAeTEKRLEELRKELEELEKKYSEEEYEELREEYLELSRE------LAGLRAELEELEKRREEI 692
                         490       500       510
                  ....*....|....*....|....*....|....*
gi 156104874 1496 NRECKNLQVQIDVLQKAKSQEKTIYKEVIRVQKDR 1530
Cdd:PRK03918  693 KKTLEKLKEELEEREKAKKELEKLEKALERVEELR 727
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1264-1452 8.87e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 8.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1264 PEVLREIDRLKAQLNELVNSHGRS---QEQLIRLQGERDEWRRERAKVETKTVSKEVV-------RHEKDPVLEKEAERL 1333
Cdd:COG4913   221 PDTFEAADALVEHFDDLERAHEALedaREQIELLEPIRELAERYAAARERLAELEYLRaalrlwfAQRRLELLEAELEEL 300
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1334 RQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDpKLREEHSRLSGSLDEEVGRRRQLEL------ 1407
Cdd:COG4913   301 RAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIE-RLERELEERERRRARLEALLAALGLplpasa 379
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 156104874 1408 --------EVQQLRAGVEEQEGLLS--FQEDRSKKLAVERELRQLTLRIQELEKR 1452
Cdd:COG4913   380 eefaalraEAAALLEALEEELEALEeaLAEAEAALRDLRRELRELEAEIASLERR 434
SPEC smart00150
Spectrin repeats;
237-330 9.66e-05

Spectrin repeats;


Pssm-ID: 197544 [Multi-domain]  Cd Length: 101  Bit Score: 43.47  E-value: 9.66e-05
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874    237 RQLSALAEQQRRILQQDwsDLMADPAGVRREYEHFK--QHELLSQEQSVNQLEDDGERMVELRHPAVGPIQAHQEALKME 314
Cdd:smart00150    8 DELEAWLEEKEQLLASE--DLGKDLESVEALLKKHEafEAELEAHEERVEALNELGEQLIEEGHPDAEEIEERLEELNER 85
                            90
                    ....*....|....*.
gi 156104874    315 WQNFLNLCICQETQLQ 330
Cdd:smart00150   86 WEELKELAEERRQKLE 101
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
795-1549 1.19e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.37  E-value: 1.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   795 QEIQSRERDRATASHLsQALQAALQDYEL-----QADTYRCSLEPTLAVSAPKRPRVAPLQESIQAQEKNLAKAYTEVAA 869
Cdd:TIGR02169  198 QQLERLRREREKAERY-QALLKEKREYEGyellkEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEE 276
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   870 AQQQLLQQLE-----FARKMLEKKELSEDIRRTHDAKQGSESPAQAGR------------ESEALKAQLEEERKRVARVQ 932
Cdd:TIGR02169  277 LNKKIKDLGEeeqlrVKEKIGELEAEIASLERSIAEKERELEDAEERLakleaeidkllaEIEELEREIEEERKRRDKLT 356
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   933 HELEAQRSQLLQLRTQ-------------RPLERLEEKEVVEFYRDPqLEGSLSRVKAQVEEEGKRRAGLQADLEVAAQK 999
Cdd:TIGR02169  357 EEYAELKEELEDLRAEleevdkefaetrdELKDYREKLEKLKREINE-LKRELDRLQEELQRLSEELADLNAAIAGIEAK 435
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1000 VVQLESKRKTMQPHLLTKEvTQVERdpgLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDVKEKVVVKEV 1079
Cdd:TIGR02169  436 INELEEEKEDKALEIKKQE-WKLEQ---LAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRA 511
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1080 VKVEKN------------LEMVKAAQAL--------RLQM-----EEDAAR------RKQAEEA----VAKLQARIEDLE 1124
Cdd:TIGR02169  512 VEEVLKasiqgvhgtvaqLGSVGERYATaievaagnRLNNvvvedDAVAKEaiellkRRKAGRAtflpLNKMRDERRDLS 591
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1125 R---------AISSVE-PKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTknATLARELSD-----------LHSKYSVV 1183
Cdd:TIGR02169  592 IlsedgvigfAVDLVEfDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRM--VTLEGELFEksgamtggsraPRGGILFS 669
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1184 EKQRPKVQ-LQERVHE-------IFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQkptVEYKEVTQ 1255
Cdd:TIGR02169  670 RSEPAELQrLRERLEGlkrelssLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKER---LEELEEDL 746
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1256 EVVRHERSpEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRhekdpvLEKEAERLRQ 1335
Cdd:TIGR02169  747 SSLEQEIE-NVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSR------IEARLREIEQ 819
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1336 EVREAAQKRRAAEDAVYELQSKRLLLERRKPEekvvvqevvvtqkdpkLREEHSRLSGSLDEEVGRRRQLELEVQQLRag 1415
Cdd:TIGR02169  820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKS----------------IEKEIENLNGKKEELEEELEELEAALRDLE-- 881
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1416 vEEQEGLLSFQEDRSKKL-AVERELRQLTLRIQELEKRPPTVQEK--IIMEEVVKLEKDPDLEKSTEALRWDLDQEKTQV 1492
Cdd:TIGR02169  882 -SRLGDLKKERDELEAQLrELERKIEELEAQIEKKRKRLSELKAKleALEEELSEIEDPKGEDEEIPEEELSLEDVQAEL 960
                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 156104874  1493 TELNRECKNLQvqiDVLQKAKSQektiYKEVIRVQKDrvLEDERARvwemLNRERTA 1549
Cdd:TIGR02169  961 QRVEEEIRALE---PVNMLAIQE----YEEVLKRLDE--LKEKRAK----LEEERKA 1004
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
1688-1716 1.36e-04

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 40.77  E-value: 1.36e-04
                           10        20
                   ....*....|....*....|....*....
gi 156104874  1688 ILEPETGKDMSPYEAYKRGIIDRGQYLQL 1716
Cdd:pfam00681   11 IIDPVTGERLSVEEAVKRGLIDPETAQKL 39
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
972-1363 1.46e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 1.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  972 LSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQverdpgldsQAAQLRIQIQQLRGEDAVISA 1051
Cdd:COG4717    76 LEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL---------QLLPLYQELEALEAELAELPE 146
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1052 RLEGLKKELLA-------LEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLE 1124
Cdd:COG4717   147 RLEELEERLEElreleeeLEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1125 RAISSVEPKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTKNATLARELSDLH------SKYSVVEKQRPKVQLQERVHE 1198
Cdd:COG4717   227 EELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLflvlglLALLFLLLAREKASLGKEAEE 306
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1199 IFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEvlraqkptvEYKEVTQEVVRHERSpevlREIDRLKAQLN 1278
Cdd:COG4717   307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIE---------ELQELLREAEELEEE----LQLEELEQEIA 373
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1279 ELVNSHG-RSQEQLIRLQGERDEWRRERAKVET--------KTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAED 1349
Cdd:COG4717   374 ALLAEAGvEDEEELRAALEQAEEYQELKEELEEleeqleelLGELEELLEALDEEELEEELEELEEELEELEEELEELRE 453
                         410
                  ....*....|....
gi 156104874 1350 AVYELQSKRLLLER 1363
Cdd:COG4717   454 ELAELEAELEQLEE 467
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
906-1131 1.55e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  906 SPAQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQrpLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKR 985
Cdd:COG4942    14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQ--LAALERRIAALARRIRALEQELAALEAELAELEKE 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  986 RAGLQADLEVAAQKVVQL------ESKRKTMQPHLLTKEVTQVERDPG-LDSQAAQLRIQIQQLRGEdaviSARLEGLKK 1058
Cdd:COG4942    92 IAELRAELEAQKEELAELlralyrLGRQPPLALLLSPEDFLDAVRRLQyLKYLAPARREQAEELRAD----LAELAALRA 167
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 156104874 1059 ELLALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVE 1131
Cdd:COG4942   168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
PLEC smart00250
Plectin repeat;
1818-1855 2.78e-04

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 40.16  E-value: 2.78e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 156104874   1818 LGLGDDSFPIAGIYDTTTDNKCSIKTAVAKNMLDPITG 1855
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
881-1365 4.74e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 4.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  881 ARKMLEKKELSEDIRRTHDAKQGSespaQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRtqrplERLEEKEVV 960
Cdd:COG4717    54 EADELFKPQGRKPELNLKELKELE----EELKEAEEKEEEYAELQEELEELEEELEELEAELEELR-----EELEKLEKL 124
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  961 EFYRDPQLEgsLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVERDPGLDSQAAQLRIQIQ 1040
Cdd:COG4717   125 LQLLPLYQE--LEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE 202
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1041 QLRGEDAVISARLEGLKKELLALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQAri 1120
Cdd:COG4717   203 ELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLF-- 280
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1121 edLERAISSVEPKVIVKEVKKVEQDPGLLQESSRLRSlLEEERTKNATLARELSDLHSKYSVVEKQRPKVQLQERVHEIF 1200
Cdd:COG4717   281 --LVLGLLALLFLLLAREKASLGKEAEELQALPALEE-LEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAE 357
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1201 QVDPE-TEQEITRLKAKLQEMAGKRSgvEKEVEKLLPDLEvlRAQKPTVEYKEVTQEVVRHERSPEVLREI---DRLKAQ 1276
Cdd:COG4717   358 ELEEElQLEELEQEIAALLAEAGVED--EEELRAALEQAE--EYQELKEELEELEEQLEELLGELEELLEAldeEELEEE 433
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1277 LNELvnshgrsQEQLIRLQGERDEWRRERAKVETKTvsKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQS 1356
Cdd:COG4717   434 LEEL-------EEELEELEEELEELREELAELEAEL--EQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEE 504

                  ....*....
gi 156104874 1357 KRLLLERRK 1365
Cdd:COG4717   505 AREEYREER 513
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1384-1591 5.22e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 5.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1384 LREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRQLTLRIQELEKRPPTVQEkiime 1463
Cdd:COG4913   615 LEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA----- 689
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1464 evvklekdpdLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEKTIYKEVIRVQKDRVLEDERARVWEML 1543
Cdd:COG4913   690 ----------LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAAL 759
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 156104874 1544 NRERTARQAREEEarrlreriDRAETLGRTWSREESELQRARDQADQE 1591
Cdd:COG4913   760 GDAVERELRENLE--------ERIDALRARLNRAEEELERAMRAFNRE 799
PLEC smart00250
Plectin repeat;
1932-1969 6.93e-04

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 39.00  E-value: 6.93e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 156104874   1932 LPHLQVQHLTGGLIDPKRTGRIPIQQALLSGMISEELA 1969
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1093-1306 7.18e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 7.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1093 QALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTKNATLARE 1172
Cdd:COG4942    30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1173 LSDL-----HSKYSVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKPT 1247
Cdd:COG4942   110 LRALyrlgrQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAA 189
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 156104874 1248 VEykevTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERA 1306
Cdd:COG4942   190 LE----ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
PTZ00121 PTZ00121
MAEBL; Provisional
786-1059 7.25e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.75  E-value: 7.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  786 KLQAQKRLTQEIQSRERDRATASHLSQALQAALQDYELQADTYRCSLEPTLAVSAPKRPRVAPLQESIQAQEKNLAKAYT 865
Cdd:PTZ00121 1491 KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK 1570
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  866 EVAAAQQQLLQQLEFARKM-------------LEKKELSEDIRRTHDAKQGSESPAQAGRE---SEALKAQLEEERKRVA 929
Cdd:PTZ00121 1571 KAEEDKNMALRKAEEAKKAeearieevmklyeEEKKMKAEEAKKAEEAKIKAEELKKAEEEkkkVEQLKKKEAEEKKKAE 1650
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  930 RVQHELEAQRSQLLQLRTQ-----------RPLERLEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQADLEVAAQ 998
Cdd:PTZ00121 1651 ELKKAEEENKIKAAEEAKKaeedkkkaeeaKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKI 1730
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 156104874  999 KVVQLESKRKTMQphlltKEVTQVERDPGLDSQAAQLRIQIQQLRGE-----DAVISarlEGLKKE 1059
Cdd:PTZ00121 1731 KAEEAKKEAEEDK-----KKAEEAKKDEEEKKKIAHLKKEEEKKAEEirkekEAVIE---EELDEE 1788
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1103-1366 8.18e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 8.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1103 AARRKQAEEAVAKLQARIEDLERAISSVEpkvivkevkkveqdpgllQESSRLRSLLEEERTKNATLARELSDLHSKYSV 1182
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALK------------------KEEKALLKQLAALERRIAALARRIRALEQELAA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1183 VEKQRPKVQLQERvheifqvdpETEQEITRLKAKLQEMAGK--RSGVEKEVEKLLPDLEVLRAQKPTVEYKEVTqevvrh 1260
Cdd:COG4942    81 LEAELAELEKEIA---------ELRAELEAQKEELAELLRAlyRLGRQPPLALLLSPEDFLDAVRRLQYLKYLA------ 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1261 ersPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRHEkdpvLEKEAERLRQEVREA 1340
Cdd:COG4942   146 ---PARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLAR----LEKELAELAAELAEL 218
                         250       260
                  ....*....|....*....|....*.
gi 156104874 1341 AQKRRAAEDAVYELQSKRLLLERRKP 1366
Cdd:COG4942   219 QQEAEELEALIARLEAEAAAAAERTP 244
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
1049-1690 8.45e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.58  E-value: 8.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1049 ISARLEGLKKELLALEKREVDVKEKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAIS 1128
Cdd:pfam02463  188 LIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKL 267
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1129 SvepKVIVKEVKKVEQDPGLLQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQrpKVQLQERVHEIFQVDPETEQ 1208
Cdd:pfam02463  268 A---QVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKE--KKKAEKELKKEKEEIEELEK 342
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1209 EITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKpTVEYKEVTQEVVRHErspEVLREIDRLKAQLNELvnsHGRSQ 1288
Cdd:pfam02463  343 ELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKK-KLESERLSSAAKLKE---EELELKSEEEKEAQLL---LELAR 415
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1289 EQLIRLQGERDEWRRERAK----VETKTVSKEVVRHEKDPVLEKEAERLRQEVREAaqKRRAAEDAVYELQSKRLLLERR 1364
Cdd:pfam02463  416 QLEDLLKEEKKEELEILEEeeesIELKQGKLTEEKEELEKQELKLLKDELELKKSE--DLLKETQLVKLQEQLELLLSRQ 493
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1365 KPEEKVVVQEVVVTQKDPKLREEHSRLSGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRQLTL 1444
Cdd:pfam02463  494 KLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTEL 573
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1445 RIQELEKRPPTVQEKIIMEEVVKLEKDPDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQEKTIYKeVI 1524
Cdd:pfam02463  574 PLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRK-GV 652
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1525 RVQKDRVLEDERARVWEMLNRERTARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALER 1604
Cdd:pfam02463  653 SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQD 732
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1605 QKQQQTLQLQEESKLLSQKTESERQKAAQRGQELSRLEaaiLREKDQIYEKERTLRDLHAKVSREELSQETQTRETNLST 1684
Cdd:pfam02463  733 KINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELS---LKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEE 809

                   ....*.
gi 156104874  1685 KISILE 1690
Cdd:pfam02463  810 LKEEAE 815
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1430-1657 8.62e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 8.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1430 SKKLAVERELRQLTLRIQELEKRpptvQEKIIMEEVVKLEKDPDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVL 1509
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKE----LAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1510 QKAKSQEKTIYKEVIRVQKDRvledERARVWEMLNRERTARQAREEEARRLRERIDRAEtLGRTWSREESELQRARDQAD 1589
Cdd:COG4942    96 RAELEAQKEELAELLRALYRL----GRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE-QAEELRADLAELAALRAELE 170
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 156104874 1590 QECGRLQQELRALERQKQQQTLQLQEESKL---LSQKTESERQKAAQRGQELSRLEAAILREKDQIYEKER 1657
Cdd:COG4942   171 AERAELEALLAELEEERAALEALKAERQKLlarLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1205-1657 1.60e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1205 ETEQEITRLKAKLQEMAGKRSGVEKEVEKLLPDLEVLRAQKptvEYKEVTQEVVRHERspevlrEIDRLKAQLNELVNSH 1284
Cdd:COG4717    85 EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL---QLLPLYQELEALEA------ELAELPERLEELEERL 155
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1285 GRSQEQLIRLQGERDEWRRERAKVETKTVSKEVVRHEKDPVLEKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERR 1364
Cdd:COG4717   156 EELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENE 235
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1365 KPEEkvvvqevvvtQKDPKLREEHSRLSG--------SLDEEVGRRRQLELEVQQLRAGVeeqeGLLSFQEDRSKKLAVE 1436
Cdd:COG4717   236 LEAA----------ALEERLKEARLLLLIaaallallGLGGSLLSLILTIAGVLFLVLGL----LALLFLLLAREKASLG 301
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1437 RELRQLtlriqELEKRPPTVQEKIIMEEVVKLEKDPDLEKStEALRWDLDQEKTQVTELNRECKNLQVQIDVLQKAKSQ- 1515
Cdd:COG4717   302 KEAEEL-----QALPALEELEEEELEELLAALGLPPDLSPE-ELLELLDRIEELQELLREAEELEEELQLEELEQEIAAl 375
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1516 --------EKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAREEEARRLRERIDRAETlgrtwSREESELQRARDQ 1587
Cdd:COG4717   376 laeagvedEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEEL-----EEELEELEEELEE 450
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 156104874 1588 ADQECGRLQQELRALERQKQQQTlqlqeesklLSQKTESERQKAAQRGQELSRLEAA--ILREKDQIYEKER 1657
Cdd:COG4717   451 LREELAELEAELEQLEEDGELAE---------LLQELEELKAELRELAEEWAALKLAleLLEEAREEYREER 513
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1494-1690 1.82e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.39  E-value: 1.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1494 ELNRECKNLQVQIDVLQKAKSQEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAREEEARRLRERIDRAETLGRT 1573
Cdd:COG1196   217 ELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1574 WSREESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRgQELSRLEAAILREKDQIY 1653
Cdd:COG1196   297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE-AELAEAEEALLEAEAELA 375
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 156104874 1654 EKERTLRDLHAKVSREELSQ-ETQTRETNLSTKISILE 1690
Cdd:COG1196   376 EAEEELEELAEELLEALRAAaELAAQLEELEEAEEALL 413
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
1408-1718 2.35e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.18  E-value: 2.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1408 EVQQLRAGVEEQEGLLSFQED-------RSKKLAVERELRQLTLRIQELEKRPPTVQEKIimeEVVKLEKDPDLE----- 1475
Cdd:pfam15921  188 EIRSILVDFEEASGKKIYEHDsmstmhfRSLGSAISKILRELDTEISYLKGRIFPVEDQL---EALKSESQNKIElllqq 264
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1476 --KSTEALRWDLDQEKTQVTE----LNRECKNLQVQIDVLQKAKSQEKTIYKevirvqkdRVLEDERARVWEMLNRERTA 1549
Cdd:pfam15921  265 hqDRIEQLISEHEVEITGLTEkassARSQANSIQSQLEIIQEQARNQNSMYM--------RQLSDLESTVSQLRSELREA 336
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1550 RQAREeearrlreriDRAETLGRTWSREESELQRAR---DQADQECG----RLQQELRALERQKQQQTLQLQEESKLLSQ 1622
Cdd:pfam15921  337 KRMYE----------DKIEELEKQLVLANSELTEARterDQFSQESGnlddQLQKLLADLHKREKELSLEKEQNKRLWDR 406
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1623 KTESE------RQKAAQRGQELSRLEAAILREKDQIY-EKERTLRDLHAK-VSREELSQETQTRETNLSTKISILEPETG 1694
Cdd:pfam15921  407 DTGNSitidhlRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKnESLEKVSSLTAQLESTKEMLRKVVEELTA 486
                          330       340
                   ....*....|....*....|....
gi 156104874  1695 KDMSpYEAYKRGIIDRGQYLQLQE 1718
Cdd:pfam15921  487 KKMT-LESSERTVSDLTASLQEKE 509
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
882-1058 2.38e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 2.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  882 RKMLEKKELSEDIRRTHDAKQGSESPAQAGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQR---PLERLEeke 958
Cdd:COG4913   265 AAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIrgnGGDRLE--- 341
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  959 vvefyrdpQLEGSLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVERDPGLDSQAAQLRIQ 1038
Cdd:COG4913   342 --------QLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAA 413
                         170       180
                  ....*....|....*....|
gi 156104874 1039 IQQLRGEDAVISARLEGLKK 1058
Cdd:COG4913   414 LRDLRRELRELEAEIASLER 433
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1385-1707 2.40e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 2.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1385 REEHSRLSGSLDEEVGRRRQLElEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRqltLRIQELEKRPPTVQEKIIMEE 1464
Cdd:TIGR02169  156 RKIIDEIAGVAEFDRKKEKALE-ELEEVEENIERLDLIIDEKRQQLERLRREREKA---ERYQALLKEKREYEGYELLKE 231
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1465 VVKLEKD-PDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDvlQKAKSQEKTIYKEVIRVQKD-RVLEDERARVWEM 1542
Cdd:TIGR02169  232 KEALERQkEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE--ELNKKIKDLGEEEQLRVKEKiGELEAEIASLERS 309
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1543 LNRERTARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERqkqqQTLQLQEESKLLSQ 1622
Cdd:TIGR02169  310 IAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA----ELEEVDKEFAETRD 385
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1623 KTESERQKAAQRGQELSRLEAAILREKDQIYEKERTLRDLHAKVSR-EELSQETQTRETNLSTKISILEPE---TGKDMS 1698
Cdd:TIGR02169  386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGiEAKINELEEEKEDKALEIKKQEWKleqLAADLS 465

                   ....*....
gi 156104874  1699 PYEAYKRGI 1707
Cdd:TIGR02169  466 KYEQELYDL 474
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1149-1511 3.15e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 3.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1149 LQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQRPKVQLQERVHEIFQVDPETEQEITRLKAKLQEMAGKRSGVE 1228
Cdd:COG4717    73 LKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELE 152
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1229 KEVEKLLPDLEVLRAQKPTVEYKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGERDEWRRERAKV 1308
Cdd:COG4717   153 ERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL 232
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1309 ETKTVSKEVVRHEKDP-------------------------------------------VLEKEAERLRQEVREAaqKRR 1345
Cdd:COG4717   233 ENELEAAALEERLKEArlllliaaallallglggsllsliltiagvlflvlgllallflLLAREKASLGKEAEEL--QAL 310
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1346 AAEDAVYELQSKRLLLERRKPEEKVVVQEVVVTQKDPKLREEHSRLSgSLDEEVgRRRQLELEVQQL--RAGVEEQEGLL 1423
Cdd:COG4717   311 PALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAE-ELEEEL-QLEELEQEIAALlaEAGVEDEEELR 388
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1424 SFQEDRSKKLAVERELRQLTLRIQELEKRpptvqekiiMEEVVKLEKDPDLEKSTEALRWDLDQEKTQVTELNRECKNLQ 1503
Cdd:COG4717   389 AALEQAEEYQELKEELEELEEQLEELLGE---------LEELLEALDEEELEEELEELEEELEELEEELEELREELAELE 459

                  ....*...
gi 156104874 1504 VQIDVLQK 1511
Cdd:COG4717   460 AELEQLEE 467
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1270-1683 3.34e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 3.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1270 IDRLKAQLNELVNSHGRsqeQLIRLQGERDEWRRERAKVETKtvskevvrhekdpvlEKEAERLRQEVREAAQKRRAAED 1349
Cdd:COG4717    48 LERLEKEADELFKPQGR---KPELNLKELKELEEELKEAEEK---------------EEEYAELQEELEELEEELEELEA 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1350 AVYELQSKRLLLERRKPEEKVVVQEVVVTQKdpkLREEHSRLsGSLDEEVGRRRQLELEVQQLRAGVEEQEGLLSfQEDR 1429
Cdd:COG4717   110 ELEELREELEKLEKLLQLLPLYQELEALEAE---LAELPERL-EELEERLEELRELEEELEELEAELAELQEELE-ELLE 184
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1430 SKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEVVKLEKDPDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQIDVL 1509
Cdd:COG4717   185 QLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGL 264
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1510 QKAKSQEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAREEEARRLRERIDRAETLGRTWSREESELQRARDQAD 1589
Cdd:COG4717   265 GGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLD 344
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874 1590 --QECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQ--KAAQRGQELSRLEAAILREKDQIYEKERTLRDLHAK 1665
Cdd:COG4717   345 riEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEElrAALEQAEEYQELKEELEELEEQLEELLGELEELLEA 424
                         410
                  ....*....|....*...
gi 156104874 1666 VSREELSQETQTRETNLS 1683
Cdd:COG4717   425 LDEEELEEELEELEEELE 442
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
917-1686 4.78e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.08  E-value: 4.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   917 LKAQLEEERKRVARVQHELEAQRSQLLQLRTQR--PLERLEEKE--VVEFYRDPQLE-GSLSRVKAQVEEEGKRRAGLQA 991
Cdd:pfam01576  227 LQAQIAELRAQLAKKEEELQAALARLEEETAQKnnALKKIRELEaqISELQEDLESErAARNKAEKQRRDLGEELEALKT 306
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874   992 DLE-----VAAQKvvQLESKRKTmqphlltkEVTQVERdpGLDSQAAQLRIQIQQLRGEDAV----ISARLEGLKKELLA 1062
Cdd:pfam01576  307 ELEdtldtTAAQQ--ELRSKREQ--------EVTELKK--ALEEETRSHEAQLQEMRQKHTQaleeLTEQLEQAKRNKAN 374
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1063 LEKrevdvkekvvvKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVkevkkv 1142
Cdd:pfam01576  375 LEK-----------AKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSK------ 437
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1143 eqdpgLLQESSRLRSLLEEERTKNATLARELSDLHSKYSVV-----EKQRPKVQLQERVHEIfqvdpetEQEITRLKAKL 1217
Cdd:pfam01576  438 -----LQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTqellqEETRQKLNLSTRLRQL-------EDERNSLQEQL 505
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1218 QEMAGKRSGVEKEVEKLLPDLEVLRAQkptVEYKEVTQEVVRHERSpEVLREIDRLKAQLNELVNSHGRSQEQLIRLQGE 1297
Cdd:pfam01576  506 EEEEEAKRNVERQLSTLQAQLSDMKKK---LEEDAGTLEALEEGKK-RLQRELEALTQQLEEKAAAYDKLEKTKNRLQQE 581
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1298 RDEWRRERAKVETKTVSKEVVRHEKDPVLEKEaerlRQEVREAAQKRRAAEDAVYELQSKRLLLERRKPEEKVVVQEVVV 1377
Cdd:pfam01576  582 LDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEE----KAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELER 657
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1378 TQKdpKLREEHSRLSGSLDEeVGR--------RRQLELEVQQLRAGVEEQEGLLSFQEDRSKKLAV---------EREL- 1439
Cdd:pfam01576  658 TNK--QLRAEMEDLVSSKDD-VGKnvhelersKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVnmqalkaqfERDLq 734
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1440 ----------RQLTLRIQELEKR--PPTVQEKIIMEEVVKLEKD-PDLEKSTEALRWDLDQEKTQVTELNRECKNLQVQI 1506
Cdd:pfam01576  735 ardeqgeekrRQLVKQVRELEAEleDERKQRAQAVAAKKKLELDlKELEAQIDAANKGREEAVKQLKKLQAQMKDLQREL 814
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1507 DVLQKAKSQEKTIYKEVIRvqKDRVLEDERARVWEMLNRERTARQAREEEARRLRERIDRAETLGRTWSREESELQRARD 1586
Cdd:pfam01576  815 EEARASRDEILAQSKESEK--KLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIA 892
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1587 QADQECGRLQQELRAL-ERQKQQQTLQLQEESKL-----LSQKTESERQKAAQRGQELSrleAAILREKDQIYEKER-TL 1659
Cdd:pfam01576  893 QLEEELEEEQSNTELLnDRLRKSTLQVEQLTTELaaersTSQKSESARQQLERQNKELK---AKLQEMEGTVKSKFKsSI 969
                          810       820
                   ....*....|....*....|....*..
gi 156104874  1660 RDLHAKVSREELSQETQTRETNLSTKI 1686
Cdd:pfam01576  970 AALEAKIAQLEEQLEQESRERQAANKL 996
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
1327-1728 5.22e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 41.88  E-value: 5.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1327 EKEAERLRQEVREAAQKRRAAEDAVYELQSKRLLLERRKpeekvVVQEVVVTQKDPKLREEHSRLsgsLDEEVGRRRQLE 1406
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAK-----KALEYYQLKEKLELEEEYLLY---LDYLKLNEERID 240
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1407 LEVQQLRAGVEEQEGLLSFQEDRSKKLAVERELRQLTLRIQELEKRPPTVQEKIIMEEVVKLEKdpdLEKSTEALRWDLD 1486
Cdd:pfam02463  241 LLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLK---LERRKVDDEEKLK 317
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1487 QEKTQVTELNRECKNLQVQIDVLQKAKS--QEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAREEEARRLRERI 1564
Cdd:pfam02463  318 ESEKEKKKAEKELKKEKEEIEELEKELKelEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL 397
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1565 DRAETLGRTWSREESELQRARDQADqecgRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRGQELSRLEAA 1644
Cdd:pfam02463  398 ELKSEEEKEAQLLLELARQLEDLLK----EEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL 473
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1645 ILREKDQIYEKERTLRDLHAKVsREELSQETQTRETNLSTKISILEPETGKDMSPYEAYKRGIIDRGQYLQLQELECDWE 1724
Cdd:pfam02463  474 LKETQLVKLQEQLELLLSRQKL-EERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVE 552

                   ....
gi 156104874  1725 EVTT 1728
Cdd:pfam02463  553 VSAT 556
PLEC smart00250
Plectin repeat;
1688-1713 5.42e-03

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 36.31  E-value: 5.42e-03
                            10        20
                    ....*....|....*....|....*.
gi 156104874   1688 ILEPETGKDMSPYEAYKRGIIDRGQY 1713
Cdd:smart00250   13 IIDPETGQKLSVEEALRRGLIDPETG 38
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
1158-1697 6.47e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 41.75  E-value: 6.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1158 LLEEERTKNATLARELSDLHSKYsvVEKQRPKVQLQERVHEI-----FQVDPETEQeitrLKAKLQEMAGKRSGVEKEVE 1232
Cdd:pfam12128  245 KLQQEFNTLESAELRLSHLHFGY--KSDETLIASRQEERQETsaelnQLLRTLDDQ----WKEKRDELNGELSAADAAVA 318
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1233 KLLPDLEVLRAQKPTVEYKEVTQEVVRHERSPEVLREIDRLKAQLNELVNSHGRSQEqlirlqgerdEWRRERAKVETKT 1312
Cdd:pfam12128  319 KDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTA----------KYNRRRSKIKEQN 388
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1313 VSKEVVRHEKdpvlekeaerlRQEVREAAQKRRAAEDAVYELQSKRLllerrkpeekvvvqEVVVTQKDPKLREEHSRLS 1392
Cdd:pfam12128  389 NRDIAGIKDK-----------LAKIREARDRQLAVAEDDLQALESEL--------------REQLEAGKLEFNEEEYRLK 443
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1393 GSLDEEVGRRRQL---ELEVQQLRAGVEEQEGLLSFQEDRSKK-LAVERELRQL-TLRIQELEKR---PPTVQEKIIMEE 1464
Cdd:pfam12128  444 SRLGELKLRLNQAtatPELLLQLENFDERIERAREEQEAANAEvERLQSELRQArKRRDQASEALrqaSRRLEERQSALD 523
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1465 VVKLEKDPDLEK-----STEALRWDLDQEKTQVTELNRECknlQVQIDVLQKAKSQEKTIYKEVIRVQKDRV-------- 1531
Cdd:pfam12128  524 ELELQLFPQAGTllhflRKEAPDWEQSIGKVISPELLHRT---DLDPEVWDGSVGGELNLYGVKLDLKRIDVpewaasee 600
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1532 -LEDERARVWEMLNRERTARQAREEEARRLRERIDRAetlgrtwSREESELQRARDQADQECGRLQQELRALERQKQQQT 1610
Cdd:pfam12128  601 eLRERLDKAEEALQSAREKQAAAEEQLVQANGELEKA-------SREETFARTALKNARLDLRRLFDEKQSEKDKKNKAL 673
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156104874  1611 LQLQEeskllsQKTESERQKAAQRGQELSRLEAAILREKDQIYEkERTLRDLHAKVSREE-------LSQETQTRETNLS 1683
Cdd:pfam12128  674 AERKD------SANERLNSLEAQLKQLDKKHQAWLEEQKEQKRE-ARTEKQAYWQVVEGAldaqlalLKAAIAARRSGAK 746
                          570
                   ....*....|....
gi 156104874  1684 TKISILEPETGKDM 1697
Cdd:pfam12128  747 AELKALETWYKRDL 760
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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