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Conserved domains on  [gi|222136686|ref|NP_004134|]
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cbp/p300-interacting transactivator 1 isoform 1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CITED super family cl24024
CITED; CITED, CBP/p300-interacting transactivator with ED-rich tail, are characterized by a ...
 87-189 7.58e-33

CITED; CITED, CBP/p300-interacting transactivator with ED-rich tail, are characterized by a conserved 32-amino acid sequence at the C-terminus. CITED proteins do not bind DNA directly and are thought to function as transcriptional co-activators.


The actual alignment was detected with superfamily member pfam04487:

Pssm-ID: 461328  Cd Length: 211  Bit Score: 116.86  E-value: 7.58e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222136686   87 PAPHLLASMHLQKLNSQYQGMaaatPGQPGEAGPLQNW----DFGAQAGGAESLSPSAgAQSPAIIDSDPVDEEVLMSLV 162
Cdd:pfam04487  99 TSQQLMASMHLQKLNTQYHGH----PLHPANGHHLGGGgqyrDGPAQLSGMQPHVPAP-MLPPNVIDTDLIDEEVLTSLV 173

                          90       100
                  ....*....|....*....|....*..
gi 222136686  163 VELGLDRANELPELWLGQNEFDFTADF 189
Cdd:pfam04487 174 LELGLDRIQELPELFLGQNEFDFMSDF 200
 
Name Accession Description Interval E-value
CITED pfam04487
CITED; CITED, CBP/p300-interacting transactivator with ED-rich tail, are characterized by a ...
 87-189 7.58e-33

CITED; CITED, CBP/p300-interacting transactivator with ED-rich tail, are characterized by a conserved 32-amino acid sequence at the C-terminus. CITED proteins do not bind DNA directly and are thought to function as transcriptional co-activators.


Pssm-ID: 461328  Cd Length: 211  Bit Score: 116.86  E-value: 7.58e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222136686   87 PAPHLLASMHLQKLNSQYQGMaaatPGQPGEAGPLQNW----DFGAQAGGAESLSPSAgAQSPAIIDSDPVDEEVLMSLV 162
Cdd:pfam04487  99 TSQQLMASMHLQKLNTQYHGH----PLHPANGHHLGGGgqyrDGPAQLSGMQPHVPAP-MLPPNVIDTDLIDEEVLTSLV 173

                          90       100
                  ....*....|....*....|....*..
gi 222136686  163 VELGLDRANELPELWLGQNEFDFTADF 189
Cdd:pfam04487 174 LELGLDRIQELPELFLGQNEFDFMSDF 200
 
Name Accession Description Interval E-value
CITED pfam04487
CITED; CITED, CBP/p300-interacting transactivator with ED-rich tail, are characterized by a ...
 87-189 7.58e-33

CITED; CITED, CBP/p300-interacting transactivator with ED-rich tail, are characterized by a conserved 32-amino acid sequence at the C-terminus. CITED proteins do not bind DNA directly and are thought to function as transcriptional co-activators.


Pssm-ID: 461328  Cd Length: 211  Bit Score: 116.86  E-value: 7.58e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222136686   87 PAPHLLASMHLQKLNSQYQGMaaatPGQPGEAGPLQNW----DFGAQAGGAESLSPSAgAQSPAIIDSDPVDEEVLMSLV 162
Cdd:pfam04487  99 TSQQLMASMHLQKLNTQYHGH----PLHPANGHHLGGGgqyrDGPAQLSGMQPHVPAP-MLPPNVIDTDLIDEEVLTSLV 173

                          90       100
                  ....*....|....*....|....*..
gi 222136686  163 VELGLDRANELPELWLGQNEFDFTADF 189
Cdd:pfam04487 174 LELGLDRIQELPELFLGQNEFDFMSDF 200
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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