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Conserved domains on  [gi|4826657|ref|NP_004333|]
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caldesmon isoform 2 [Homo sapiens]

Protein Classification

Caldesmon domain-containing protein( domain architecture ID 12029883)

Caldesmon domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Caldesmon pfam02029
Caldesmon;
53-525 4.95e-161

Caldesmon;


:

Pssm-ID: 460421 [Multi-domain]  Cd Length: 495  Bit Score: 467.42  E-value: 4.95e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4826657     53 KQEEESLGQVTDQVEVNAQNSVpdEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSL 132
Cdd:pfam02029  23 KEEEEPSGQVTESVEPNEHNSY--EEDSELKPSGQGGLDEEEAFLDRTAKREERRQKRLQEALERQKEFDPTIADEKESV 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4826657    133 PSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKK---EDKEKEEEEEEKPKRGSIGENQIK 209
Cdd:pfam02029 101 AERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTEVRQAEeegEEEEDKSEEAEEVPTENFAKEEVK 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4826657    210 DEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENtfSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRG 289
Cdd:pfam02029 181 DEKIKKEKKVKYESKVFLDQKRGHPEVKSQNGEEEVTKLKVTTK--RRQGGLSQSQEREEEAEVFLEAEQKLEELRRRRQ 258
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4826657    290 ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPE 369
Cdd:pfam02029 259 EKESEEFEKLRQKQQEAELELEELKKKREERRKLLEEEEQRRKQEEAERKLREEEEKRRMKEEIERRRAEAAEKRQKLPE 338
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4826657    370 DGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIE-GTKSAKPTKPAASDLP 448
Cdd:pfam02029 339 DSSSEGKKPFKCFSPKGSSLKITERAEFLNKSLQKSSSVKKTHPPAVVSKIDSRLEQYTSAIEsSTKEAKPTKPAASDLP 418
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 4826657    449 VPAEGVRNIKSMWEKGNVFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWE 525
Cdd:pfam02029 419 VPAEGVRNIKSMWEKGNVFSSPGAKGTPNKETAGLKVGVASRINEWLKKTPEGSKSPAPKPSDLRPGDVSGKRNLWE 495
 
Name Accession Description Interval E-value
Caldesmon pfam02029
Caldesmon;
53-525 4.95e-161

Caldesmon;


Pssm-ID: 460421 [Multi-domain]  Cd Length: 495  Bit Score: 467.42  E-value: 4.95e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4826657     53 KQEEESLGQVTDQVEVNAQNSVpdEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSL 132
Cdd:pfam02029  23 KEEEEPSGQVTESVEPNEHNSY--EEDSELKPSGQGGLDEEEAFLDRTAKREERRQKRLQEALERQKEFDPTIADEKESV 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4826657    133 PSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKK---EDKEKEEEEEEKPKRGSIGENQIK 209
Cdd:pfam02029 101 AERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTEVRQAEeegEEEEDKSEEAEEVPTENFAKEEVK 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4826657    210 DEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENtfSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRG 289
Cdd:pfam02029 181 DEKIKKEKKVKYESKVFLDQKRGHPEVKSQNGEEEVTKLKVTTK--RRQGGLSQSQEREEEAEVFLEAEQKLEELRRRRQ 258
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4826657    290 ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPE 369
Cdd:pfam02029 259 EKESEEFEKLRQKQQEAELELEELKKKREERRKLLEEEEQRRKQEEAERKLREEEEKRRMKEEIERRRAEAAEKRQKLPE 338
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4826657    370 DGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIE-GTKSAKPTKPAASDLP 448
Cdd:pfam02029 339 DSSSEGKKPFKCFSPKGSSLKITERAEFLNKSLQKSSSVKKTHPPAVVSKIDSRLEQYTSAIEsSTKEAKPTKPAASDLP 418
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 4826657    449 VPAEGVRNIKSMWEKGNVFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWE 525
Cdd:pfam02029 419 VPAEGVRNIKSMWEKGNVFSSPGAKGTPNKETAGLKVGVASRINEWLKKTPEGSKSPAPKPSDLRPGDVSGKRNLWE 495
 
Name Accession Description Interval E-value
Caldesmon pfam02029
Caldesmon;
53-525 4.95e-161

Caldesmon;


Pssm-ID: 460421 [Multi-domain]  Cd Length: 495  Bit Score: 467.42  E-value: 4.95e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4826657     53 KQEEESLGQVTDQVEVNAQNSVpdEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSL 132
Cdd:pfam02029  23 KEEEEPSGQVTESVEPNEHNSY--EEDSELKPSGQGGLDEEEAFLDRTAKREERRQKRLQEALERQKEFDPTIADEKESV 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4826657    133 PSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKK---EDKEKEEEEEEKPKRGSIGENQIK 209
Cdd:pfam02029 101 AERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTEVRQAEeegEEEEDKSEEAEEVPTENFAKEEVK 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4826657    210 DEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENtfSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRG 289
Cdd:pfam02029 181 DEKIKKEKKVKYESKVFLDQKRGHPEVKSQNGEEEVTKLKVTTK--RRQGGLSQSQEREEEAEVFLEAEQKLEELRRRRQ 258
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4826657    290 ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPE 369
Cdd:pfam02029 259 EKESEEFEKLRQKQQEAELELEELKKKREERRKLLEEEEQRRKQEEAERKLREEEEKRRMKEEIERRRAEAAEKRQKLPE 338
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4826657    370 DGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIE-GTKSAKPTKPAASDLP 448
Cdd:pfam02029 339 DSSSEGKKPFKCFSPKGSSLKITERAEFLNKSLQKSSSVKKTHPPAVVSKIDSRLEQYTSAIEsSTKEAKPTKPAASDLP 418
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 4826657    449 VPAEGVRNIKSMWEKGNVFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWE 525
Cdd:pfam02029 419 VPAEGVRNIKSMWEKGNVFSSPGAKGTPNKETAGLKVGVASRINEWLKKTPEGSKSPAPKPSDLRPGDVSGKRNLWE 495
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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