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Conserved domains on  [gi|48255933|ref|NP_004956|]
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non-histone chromosomal protein HMG-14 [Homo sapiens]

Protein Classification

high mobility group family protein( domain architecture ID 10471271)

high mobility group (HMG) family protein similar to human non-histone chromosomal protein HMG-14, also called high mobility group nucleosome-binding domain-containing protein 1, that binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HMG14_17 pfam01101
HMG14 and HMG17;
2-95 1.16e-17

HMG14 and HMG17;


:

Pssm-ID: 460064 [Multi-domain]  Cd Length: 90  Bit Score: 70.88  E-value: 1.16e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48255933     2 PKRKVSSAEGAAKEEPKRRSARLSAKPpakvEAKPKKAAAKDKSSDKKVQTKGKRGAKGKQAEVANQETKEDLPAENGET 81
Cdd:pfam01101   1 PKRKASSDKGKVKEEPKRRSARLSAKP----APPKPEPKPKKASSDKKKGTKGKKGAKGKAAAGANQEKKGDNPAENGEA 76

                          90
                  ....*....|....
gi 48255933    82 KTEESPASDEAGEK 95
Cdd:pfam01101  77 KTEESPKSEGAGEK 90
 
Name Accession Description Interval E-value
HMG14_17 pfam01101
HMG14 and HMG17;
2-95 1.16e-17

HMG14 and HMG17;


Pssm-ID: 460064 [Multi-domain]  Cd Length: 90  Bit Score: 70.88  E-value: 1.16e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48255933     2 PKRKVSSAEGAAKEEPKRRSARLSAKPpakvEAKPKKAAAKDKSSDKKVQTKGKRGAKGKQAEVANQETKEDLPAENGET 81
Cdd:pfam01101   1 PKRKASSDKGKVKEEPKRRSARLSAKP----APPKPEPKPKKASSDKKKGTKGKKGAKGKAAAGANQEKKGDNPAENGEA 76

                          90
                  ....*....|....
gi 48255933    82 KTEESPASDEAGEK 95
Cdd:pfam01101  77 KTEESPKSEGAGEK 90
HMG17 smart00527
domain in high mobilty group proteins HMG14 and HMG 17;
2-92 1.78e-12

domain in high mobilty group proteins HMG14 and HMG 17;


Pssm-ID: 197773 [Multi-domain]  Cd Length: 88  Bit Score: 57.65  E-value: 1.78e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48255933      2 PKRKVSSAEGAAKEEPKRRSARLSAKpPAKVEAKPKKAAAKDKSSDKKVQTKGKRGAKGKQAEVANQEtkEDLPAENGET 81
Cdd:smart00527   1 PKRKVAAGEGDDKDEPKRRSARLSAK-PAPPKPEPKPKKAAAKKKSENVAAKGKKGAKGKQTEEAGKE--ENNPAENGET 77

                           90
                   ....*....|.
gi 48255933     82 KTEESPASDEA 92
Cdd:smart00527  78 KSEEAPAAEGA 88
 
Name Accession Description Interval E-value
HMG14_17 pfam01101
HMG14 and HMG17;
2-95 1.16e-17

HMG14 and HMG17;


Pssm-ID: 460064 [Multi-domain]  Cd Length: 90  Bit Score: 70.88  E-value: 1.16e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48255933     2 PKRKVSSAEGAAKEEPKRRSARLSAKPpakvEAKPKKAAAKDKSSDKKVQTKGKRGAKGKQAEVANQETKEDLPAENGET 81
Cdd:pfam01101   1 PKRKASSDKGKVKEEPKRRSARLSAKP----APPKPEPKPKKASSDKKKGTKGKKGAKGKAAAGANQEKKGDNPAENGEA 76

                          90
                  ....*....|....
gi 48255933    82 KTEESPASDEAGEK 95
Cdd:pfam01101  77 KTEESPKSEGAGEK 90
HMG17 smart00527
domain in high mobilty group proteins HMG14 and HMG 17;
2-92 1.78e-12

domain in high mobilty group proteins HMG14 and HMG 17;


Pssm-ID: 197773 [Multi-domain]  Cd Length: 88  Bit Score: 57.65  E-value: 1.78e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 48255933      2 PKRKVSSAEGAAKEEPKRRSARLSAKpPAKVEAKPKKAAAKDKSSDKKVQTKGKRGAKGKQAEVANQEtkEDLPAENGET 81
Cdd:smart00527   1 PKRKVAAGEGDDKDEPKRRSARLSAK-PAPPKPEPKPKKAAAKKKSENVAAKGKKGAKGKQTEEAGKE--ENNPAENGET 77

                           90
                   ....*....|.
gi 48255933     82 KTEESPASDEA 92
Cdd:smart00527  78 KSEEAPAAEGA 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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