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Conserved domains on  [gi|4885279|ref|NP_005260|]
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zinc finger protein GLI1 isoform 1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
562-1081 4.93e-09

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.11  E-value: 4.93e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    562 ASPFPPGSPPENGASSLPGLMPAQH-YLLRARYASARGGGTSPTAASSLDRIGGLPMPP--WRSRAEYPGYNPNAGVTRR 638
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVpPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrPRRRAARPTVGSLTSLADP 2701
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    639 ASDPAQAADRPAPArvqrfksLGCVHTPPTVAGGGQNFdPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 718
Cdd:PHA03247 2702 PPPPPTPEPAPHAL-------VSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    719 NPYMDFPPTDTLGYGGPEGAAAEPY-GARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALG 797
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    798 GTYSQCprlehyGQVQVKPEQGCPVGSDSTGLAPclnahPSEGPPHPQPLFSHYPQPSPPqylqSGPYTQPPPDyLPSEP 877
Cdd:PHA03247 2854 GSVAPG------GDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPP----DQPERPPQPQ-APPPP 2917
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    878 RPCLDFDSPTHSTGQLKAQlvcnyVQSQQELLWEGGgreDAPAQEPSYQSPKFLGGSQVsPSRAKAPvNTYGPgfgPNLP 957
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPP-----PRPQPPLAPTTD---PAGAGEPSGAVPQPWLGALV-PGRVAVP-RFRVP---QPAP 2984
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    958 NHKSGSYPTPSPCHenfvvgaNRASHRAAAPPRLLPPLPTCYGPLKVGGTnpscghpevgrlgggpaLYPPPEGQVCNPL 1037
Cdd:PHA03247 2985 SREAPASSTPPLTG-------HSLSRVSSWASSLALHEETDPPPVSLKQT-----------------LWPPDDTEDSDAD 3040
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 4885279   1038 DSLDLDNTQLDFVAILDEPQGLSPPPSHdqrgssghtPPPSGPP 1081
Cdd:PHA03247 3041 SLFDSDSERSDLEALDPLPPEPHDPFAH---------EPDPATP 3075
FOXP-CC super family cl24666
FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found ...
237-265 2.59e-06

FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins in various Mammalia species. It is a coiled-coil domain, which modulates the dimeric associations of FOXP transcription factors. Several key disease mutations, for instance those found in the IPEX syndrome are located in this domain


The actual alignment was detected with superfamily member pfam16159:

Pssm-ID: 465036  Cd Length: 68  Bit Score: 45.75  E-value: 2.59e-06
                           10        20
                   ....*....|....*....|....*....
gi 4885279     237 CRWDGCSQEFDSQEQLVHHINSEHIHGER 265
Cdd:pfam16159    7 CRWPGCETVCEDFGSFLKHLNSEHALDDR 35
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
297-387 5.15e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.10  E-value: 5.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279   297 GEKPHKCTFEGCRKSYSRLENLKTHLRshtgekpymceHEGCSKAFSNASDRAKHQNRTHSNeKPYVCklPGCTKRYTDP 376
Cdd:COG5189  346 DGKPYKCPVEGCNKKYKNQNGLKYHML-----------HGHQNQKLHENPSPEKMNIFSAKD-KPYRC--EVCDKRYKNL 411
                         90
                 ....*....|.
gi 4885279   377 SSLRKHVKTVH 387
Cdd:COG5189  412 NGLKYHRKHSH 422
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
562-1081 4.93e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.11  E-value: 4.93e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    562 ASPFPPGSPPENGASSLPGLMPAQH-YLLRARYASARGGGTSPTAASSLDRIGGLPMPP--WRSRAEYPGYNPNAGVTRR 638
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVpPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrPRRRAARPTVGSLTSLADP 2701
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    639 ASDPAQAADRPAPArvqrfksLGCVHTPPTVAGGGQNFdPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 718
Cdd:PHA03247 2702 PPPPPTPEPAPHAL-------VSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    719 NPYMDFPPTDTLGYGGPEGAAAEPY-GARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALG 797
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    798 GTYSQCprlehyGQVQVKPEQGCPVGSDSTGLAPclnahPSEGPPHPQPLFSHYPQPSPPqylqSGPYTQPPPDyLPSEP 877
Cdd:PHA03247 2854 GSVAPG------GDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPP----DQPERPPQPQ-APPPP 2917
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    878 RPCLDFDSPTHSTGQLKAQlvcnyVQSQQELLWEGGgreDAPAQEPSYQSPKFLGGSQVsPSRAKAPvNTYGPgfgPNLP 957
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPP-----PRPQPPLAPTTD---PAGAGEPSGAVPQPWLGALV-PGRVAVP-RFRVP---QPAP 2984
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    958 NHKSGSYPTPSPCHenfvvgaNRASHRAAAPPRLLPPLPTCYGPLKVGGTnpscghpevgrlgggpaLYPPPEGQVCNPL 1037
Cdd:PHA03247 2985 SREAPASSTPPLTG-------HSLSRVSSWASSLALHEETDPPPVSLKQT-----------------LWPPDDTEDSDAD 3040
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 4885279   1038 DSLDLDNTQLDFVAILDEPQGLSPPPSHdqrgssghtPPPSGPP 1081
Cdd:PHA03247 3041 SLFDSDSERSDLEALDPLPPEPHDPFAH---------EPDPATP 3075
FOXP-CC pfam16159
FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found ...
237-265 2.59e-06

FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins in various Mammalia species. It is a coiled-coil domain, which modulates the dimeric associations of FOXP transcription factors. Several key disease mutations, for instance those found in the IPEX syndrome are located in this domain


Pssm-ID: 465036  Cd Length: 68  Bit Score: 45.75  E-value: 2.59e-06
                           10        20
                   ....*....|....*....|....*....
gi 4885279     237 CRWDGCSQEFDSQEQLVHHINSEHIHGER 265
Cdd:pfam16159    7 CRWPGCETVCEDFGSFLKHLNSEHALDDR 35
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
297-387 5.15e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.10  E-value: 5.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279   297 GEKPHKCTFEGCRKSYSRLENLKTHLRshtgekpymceHEGCSKAFSNASDRAKHQNRTHSNeKPYVCklPGCTKRYTDP 376
Cdd:COG5189  346 DGKPYKCPVEGCNKKYKNQNGLKYHML-----------HGHQNQKLHENPSPEKMNIFSAKD-KPYRC--EVCDKRYKNL 411
                         90
                 ....*....|.
gi 4885279   377 SSLRKHVKTVH 387
Cdd:COG5189  412 NGLKYHRKHSH 422
zf-H2C2_2 pfam13465
Zinc-finger double domain;
317-344 2.66e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.97  E-value: 2.66e-05
                           10        20
                   ....*....|....*....|....*...
gi 4885279     317 NLKTHLRSHTGEKPYMCEHegCSKAFSN 344
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
COG5236 COG5236
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
196-433 2.31e-03

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


Pssm-ID: 227561 [Multi-domain]  Cd Length: 493  Bit Score: 41.93  E-value: 2.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279   196 EGDMSSPNSTGIQDPLLGMLDGREDLereeKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEH-------IHGERKEF 268
Cdd:COG5236  117 PADITDRRQWKGREEKVGIFYEGEDV----RDEMEDLLSFKCPKSKCHRRCGSLKELKKHYKAQHgfvlcseCIGNKKDF 192
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279   269 VChwggcsrELRPFKAQymlvvHMRRH-------TGEKPH-KCTFegCRKSYSRLENLKTHLRSHTgEKPYMCEHEGCS- 339
Cdd:COG5236  193 WN-------EIRLFRSS-----TLRDHknggleeEGFKGHpLCIF--CKIYFYDDDELRRHCRLRH-EACHICDMVGPIr 257
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279   340 -KAFSNASDRAKHQNRTHsnekpYVCKLPGCTKR----YTDPSSLRKHVKTVHGPDAHVT----------------KRHR 398
Cdd:COG5236  258 yQYFKSYEDLEAHFRNAH-----YCCTFQTCRVGkcyvFPYHTELLEHLTRFHKVNARLSeiprpgrcsipvmdpfKRKK 332
                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 4885279   399 GDGPLPRAPSI--STVEPKREREGGPIREESRLTVPE 433
Cdd:COG5236  333 APARVSVIDPSggNARAPMAHRGGSRQDTASPSTEAE 369
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
562-1081 4.93e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.11  E-value: 4.93e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    562 ASPFPPGSPPENGASSLPGLMPAQH-YLLRARYASARGGGTSPTAASSLDRIGGLPMPP--WRSRAEYPGYNPNAGVTRR 638
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVpPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrPRRRAARPTVGSLTSLADP 2701
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    639 ASDPAQAADRPAPArvqrfksLGCVHTPPTVAGGGQNFdPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 718
Cdd:PHA03247 2702 PPPPPTPEPAPHAL-------VSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    719 NPYMDFPPTDTLGYGGPEGAAAEPY-GARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALG 797
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    798 GTYSQCprlehyGQVQVKPEQGCPVGSDSTGLAPclnahPSEGPPHPQPLFSHYPQPSPPqylqSGPYTQPPPDyLPSEP 877
Cdd:PHA03247 2854 GSVAPG------GDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPP----DQPERPPQPQ-APPPP 2917
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    878 RPCLDFDSPTHSTGQLKAQlvcnyVQSQQELLWEGGgreDAPAQEPSYQSPKFLGGSQVsPSRAKAPvNTYGPgfgPNLP 957
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPP-----PRPQPPLAPTTD---PAGAGEPSGAVPQPWLGALV-PGRVAVP-RFRVP---QPAP 2984
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    958 NHKSGSYPTPSPCHenfvvgaNRASHRAAAPPRLLPPLPTCYGPLKVGGTnpscghpevgrlgggpaLYPPPEGQVCNPL 1037
Cdd:PHA03247 2985 SREAPASSTPPLTG-------HSLSRVSSWASSLALHEETDPPPVSLKQT-----------------LWPPDDTEDSDAD 3040
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 4885279   1038 DSLDLDNTQLDFVAILDEPQGLSPPPSHdqrgssghtPPPSGPP 1081
Cdd:PHA03247 3041 SLFDSDSERSDLEALDPLPPEPHDPFAH---------EPDPATP 3075
FOXP-CC pfam16159
FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found ...
237-265 2.59e-06

FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins in various Mammalia species. It is a coiled-coil domain, which modulates the dimeric associations of FOXP transcription factors. Several key disease mutations, for instance those found in the IPEX syndrome are located in this domain


Pssm-ID: 465036  Cd Length: 68  Bit Score: 45.75  E-value: 2.59e-06
                           10        20
                   ....*....|....*....|....*....
gi 4885279     237 CRWDGCSQEFDSQEQLVHHINSEHIHGER 265
Cdd:pfam16159    7 CRWPGCETVCEDFGSFLKHLNSEHALDDR 35
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
297-387 5.15e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.10  E-value: 5.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279   297 GEKPHKCTFEGCRKSYSRLENLKTHLRshtgekpymceHEGCSKAFSNASDRAKHQNRTHSNeKPYVCklPGCTKRYTDP 376
Cdd:COG5189  346 DGKPYKCPVEGCNKKYKNQNGLKYHML-----------HGHQNQKLHENPSPEKMNIFSAKD-KPYRC--EVCDKRYKNL 411
                         90
                 ....*....|.
gi 4885279   377 SSLRKHVKTVH 387
Cdd:COG5189  412 NGLKYHRKHSH 422
zf-H2C2_2 pfam13465
Zinc-finger double domain;
317-344 2.66e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.97  E-value: 2.66e-05
                           10        20
                   ....*....|....*....|....*...
gi 4885279     317 NLKTHLRSHTGEKPYMCEHegCSKAFSN 344
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
PRK10263 PRK10263
DNA translocase FtsK; Provisional
725-877 3.10e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 48.54  E-value: 3.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    725 PPTDTLGYGGPEGAAAEPYGARGPGSLPLGPGP---PTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKAlgGTYS 801
Cdd:PRK10263  339 PVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPviaPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAA--EQPA 416
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 4885279    802 QCPRLEHYGQVQVKPEQGCPVGSDSTGLAPcLNAHPSEGPPHPQPLF---SHYPQPSPPQYLQSGPYTQPPPDYLPSEP 877
Cdd:PRK10263  417 QQPYYAPAPEQPAQQPYYAPAPEQPVAGNA-WQAEEQQSTFAPQSTYqteQTYQQPAAQEPLYQQPQPVEQQPVVEPEP 494
zf-H2C2_2 pfam13465
Zinc-finger double domain;
287-314 3.20e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.59  E-value: 3.20e-05
                           10        20
                   ....*....|....*....|....*...
gi 4885279     287 MLVVHMRRHTGEKPHKCTFegCRKSYSR 314
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
PHA03247 PHA03247
large tegument protein UL36; Provisional
511-870 1.02e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 1.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    511 PIGTRGLKLPSLSHTGTTVSRRVGPPVSLERRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLPglmpaqhyllr 590
Cdd:PHA03247 2751 PGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALP----------- 2819
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    591 aryASARGGGTSPTAASSLDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSLGCVHTPPTVA 670
Cdd:PHA03247 2820 ---PAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTE 2896
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    671 GGGQNFD-PYLPTSVYSPQPPSITENAAMDARGLQEEPEvgtsmvgSGLNPYMDFPPTDTLGYGGPEGAAAEPY-GARGP 748
Cdd:PHA03247 2897 SFALPPDqPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP-------PPRPQPPLAPTTDPAGAGEPSGAVPQPWlGALVP 2969
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    749 GSLPL------GPGPPTNYGPNPCPQQASYPDPTQETWGE-FPSHSGLYPGPKALGGTYSQCPRLEHYGQVQVKPEQgcP 821
Cdd:PHA03247 2970 GRVAVprfrvpQPAPSREAPASSTPPLTGHSLSRVSSWASsLALHEETDPPPVSLKQTLWPPDDTEDSDADSLFDSD--S 3047
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 4885279    822 VGSDSTGLAPclnahpseGPPHPQPLFSHYPQPSPPQY-LQSGPYTQ--PPP 870
Cdd:PHA03247 3048 ERSDLEALDP--------LPPEPHDPFAHEPDPATPEAgARESPSSQfgPPP 3091
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
299-379 3.23e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 44.69  E-value: 3.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279   299 KPHKCtfEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNaSDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSS 378
Cdd:COG5048   32 RPDSC--PNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSR-PLELSRHLRTHHNNPSDLNSKSLPLSNSKASSS 108

                 .
gi 4885279   379 L 379
Cdd:COG5048  109 S 109
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
291-347 4.22e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 44.30  E-value: 4.22e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 4885279   291 HMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASD 347
Cdd:COG5048   52 HIRSHTGEKPSQCSYSGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSS 108
dnaA PRK14086
chromosomal replication initiator protein DnaA;
763-983 4.86e-04

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 44.05  E-value: 4.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    763 PNPCPQQASYPDPTQETWGEFPSHSglYPGPKALggtysqcPRLEHYGQVQVKPEqgcpvgsdSTGLAPCLNAHPSEGPp 842
Cdd:PRK14086   96 APPPPHARRTSEPELPRPGRRPYEG--YGGPRAD-------DRPPGLPRQDQLPT--------ARPAYPAYQQRPEPGA- 157
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    843 HPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEP-RPCLDFDSPTHSTGQLKaqlvcnyvQSQQELLWEGGGREDAPAQ 921
Cdd:PRK14086  158 WPRAADDYGWQQQRLGFPPRAPYASPASYAPEQERdREPYDAGRPEYDQRRRD--------YDHPRPDWDRPRRDRTDRP 229
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 4885279    922 EPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHKSgSYPTPSPCH---------ENFVVGA-NRASH 983
Cdd:PRK14086  230 EPPPGAGHVHRGGPGPPERDDAPVVPIRPSAPGPLAAQPA-PAPGPGEPTarlnpkytfDTFVIGAsNRFAH 300
PHA03247 PHA03247
large tegument protein UL36; Provisional
562-1039 1.07e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    562 ASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAASsldrigglPMPPWRSRAEYPGYNPNAgvtrrASD 641
Cdd:PHA03247 2552 PPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSAR--------PRAPVDDRGDPRGPAPPS-----PLP 2618
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    642 PAQAA-DRPAPARVQRFKSLGCVHTPPTVAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSgLNP 720
Cdd:PHA03247 2619 PDTHApDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGS-LTS 2697
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    721 YMDFPPtdtlgyggPEGAAAEPYGARGPGsLPLGPGPPTNYGPNPCPQQASYPDPTQETwGEFPSHSGLYPGPKALGGTY 800
Cdd:PHA03247 2698 LADPPP--------PPPTPEPAPHALVSA-TPLPPGPAAARQASPALPAAPAPPAVPAG-PATPGGPARPARPPTTAGPP 2767
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    801 SQCPrlehyGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPC 880
Cdd:PHA03247 2768 APAP-----PAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPP 2842
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    881 LDFDSPTHSTgqlkaqlvCNYVQSQQELLWEGGGREDAPA-QEPSYQSPKFLGGSQVSPSRAKAPVNTYGPgfgPNLPNH 959
Cdd:PHA03247 2843 PGPPPPSLPL--------GGSVAPGGDVRRRPPSRSPAAKpAAPARPPVRRLARPAVSRSTESFALPPDQP---ERPPQP 2911
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    960 KSGSYPTPSPCHENfvvgANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLggGPALYPPPEGQVCNPLDS 1039
Cdd:PHA03247 2912 QAPPPPQPQPQPPP----PPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAL--VPGRVAVPRFRVPQPAPS 2985
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
520-652 1.93e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 1.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279    520 PSLSHTGTTVSRRVGPPVSLERRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGG 599
Cdd:PRK12323  365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGP 444
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 4885279    600 GTSPTAASSLdriggLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPA 652
Cdd:PRK12323  445 GGAPAPAPAP-----AAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPA 492
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
275-382 2.27e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 41.99  E-value: 2.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279   275 CSRELRPFKAQYMLVVHMR--RHTGE--KPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAK 350
Cdd:COG5048  292 SKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNEP 371
                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 4885279   351 HQ----NRTHSNEKPYVCKLPGCTKRYTDPSSLRKH 382
Cdd:COG5048  372 PQslqqYKDLKNDKKSETLSNSCIRNFKRDSNLSLH 407
COG5236 COG5236
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
196-433 2.31e-03

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


Pssm-ID: 227561 [Multi-domain]  Cd Length: 493  Bit Score: 41.93  E-value: 2.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279   196 EGDMSSPNSTGIQDPLLGMLDGREDLereeKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEH-------IHGERKEF 268
Cdd:COG5236  117 PADITDRRQWKGREEKVGIFYEGEDV----RDEMEDLLSFKCPKSKCHRRCGSLKELKKHYKAQHgfvlcseCIGNKKDF 192
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279   269 VChwggcsrELRPFKAQymlvvHMRRH-------TGEKPH-KCTFegCRKSYSRLENLKTHLRSHTgEKPYMCEHEGCS- 339
Cdd:COG5236  193 WN-------EIRLFRSS-----TLRDHknggleeEGFKGHpLCIF--CKIYFYDDDELRRHCRLRH-EACHICDMVGPIr 257
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4885279   340 -KAFSNASDRAKHQNRTHsnekpYVCKLPGCTKR----YTDPSSLRKHVKTVHGPDAHVT----------------KRHR 398
Cdd:COG5236  258 yQYFKSYEDLEAHFRNAH-----YCCTFQTCRVGkcyvFPYHTELLEHLTRFHKVNARLSeiprpgrcsipvmdpfKRKK 332
                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 4885279   399 GDGPLPRAPSI--STVEPKREREGGPIREESRLTVPE 433
Cdd:COG5236  333 APARVSVIDPSggNARAPMAHRGGSRQDTASPSTEAE 369
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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