NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|33695109|ref|NP_005824|]
View 

rab9 effector protein with kelch motifs isoform a [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
13-270 3.10e-28

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 111.40  E-value: 3.10e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  13 PRKATWYTLtvpGDSPCARVGHSCSYLPpvgnakRGKVFIVGGANPN----RSFSDVHTMDLGKHQWdldTCKGLLP--R 86
Cdd:COG3055  45 PATNTWSEL---APLPGPPRHHAAAVAQ------DGKLYVFGGFTGAnpssTPLNDVYVYDPATNTW---TKLAPMPtpR 112

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  87 YEHASFIPSctpDRIWVFGGANQSGNRNCLQVLNPETRTWTTpevTSPPPSPRTFHTSSAAIGNQLYVFGGGErgaqpvq 166
Cdd:COG3055 113 GGATALLLD---GKIYVVGGWDDGGNVAWVEVYDPATGTWTQ---LAPLPTPRDHLAAAVLPDGKILVIGGRN------- 179

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109 167 dtklhvFDANTLTWSqpeTLGNPPSPRHGHVMVAAGTKLFIHGGLAGdrFYDDLHCIDISDMKWQKLNPTgaaPAGCAAH 246
Cdd:COG3055 180 ------GSGFSNTWT---TLAPLPTARAGHAAAVLGGKILVFGGESG--FSDEVEAYDPATNTWTALGEL---PTPRHGH 245

                       250       260
                ....*....|....*....|....
gi 33695109 247 SAVAMGKHVYIFGGMTPAGALDTM 270
Cdd:COG3055 246 AAVLTDGKVYVIGGETKPGVRTPL 269
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
13-270 3.10e-28

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 111.40  E-value: 3.10e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  13 PRKATWYTLtvpGDSPCARVGHSCSYLPpvgnakRGKVFIVGGANPN----RSFSDVHTMDLGKHQWdldTCKGLLP--R 86
Cdd:COG3055  45 PATNTWSEL---APLPGPPRHHAAAVAQ------DGKLYVFGGFTGAnpssTPLNDVYVYDPATNTW---TKLAPMPtpR 112

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  87 YEHASFIPSctpDRIWVFGGANQSGNRNCLQVLNPETRTWTTpevTSPPPSPRTFHTSSAAIGNQLYVFGGGErgaqpvq 166
Cdd:COG3055 113 GGATALLLD---GKIYVVGGWDDGGNVAWVEVYDPATGTWTQ---LAPLPTPRDHLAAAVLPDGKILVIGGRN------- 179

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109 167 dtklhvFDANTLTWSqpeTLGNPPSPRHGHVMVAAGTKLFIHGGLAGdrFYDDLHCIDISDMKWQKLNPTgaaPAGCAAH 246
Cdd:COG3055 180 ------GSGFSNTWT---TLAPLPTARAGHAAAVLGGKILVFGGESG--FSDEVEAYDPATNTWTALGEL---PTPRHGH 245

                       250       260
                ....*....|....*....|....
gi 33695109 247 SAVAMGKHVYIFGGMTPAGALDTM 270
Cdd:COG3055 246 AAVLTDGKVYVIGGETKPGVRTPL 269
PLN02193 PLN02193
nitrile-specifier protein
 126-280 2.81e-20

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 91.94  E-value: 2.81e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  126 WTTPEVTSPPPSPRTFHtSSAAIGNQLYVFGGGERGAQPVqDTKLHVFDANTLTWS-QPETLGNPPSPRHGHVMVAAGTK 204
Cdd:PLN02193 153 WIKVEQKGEGPGLRCSH-GIAQVGNKIYSFGGEFTPNQPI-DKHLYVFDLETRTWSiSPATGDVPHLSCLGVRMVSIGST 230

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 33695109  205 LFIHGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQHW 280
Cdd:PLN02193 231 LYVFGGRDASRQYNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVSATARLKTLDSYNIVDKKW 306
Kelch_3 pfam13415
Galactose oxidase, central domain;
149-201 1.26e-06

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 44.97  E-value: 1.26e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 33695109   149 GNQLYVFGGGERGAQPVqDTKLHVFDANTLTWsqpETLGNPPSPRHGHVMVAA 201
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTR-LNDLYVYDLDTNTW---TQIGDLPPPRSGHSATYI 49
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
13-270 3.10e-28

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 111.40  E-value: 3.10e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  13 PRKATWYTLtvpGDSPCARVGHSCSYLPpvgnakRGKVFIVGGANPN----RSFSDVHTMDLGKHQWdldTCKGLLP--R 86
Cdd:COG3055  45 PATNTWSEL---APLPGPPRHHAAAVAQ------DGKLYVFGGFTGAnpssTPLNDVYVYDPATNTW---TKLAPMPtpR 112

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  87 YEHASFIPSctpDRIWVFGGANQSGNRNCLQVLNPETRTWTTpevTSPPPSPRTFHTSSAAIGNQLYVFGGGErgaqpvq 166
Cdd:COG3055 113 GGATALLLD---GKIYVVGGWDDGGNVAWVEVYDPATGTWTQ---LAPLPTPRDHLAAAVLPDGKILVIGGRN------- 179

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109 167 dtklhvFDANTLTWSqpeTLGNPPSPRHGHVMVAAGTKLFIHGGLAGdrFYDDLHCIDISDMKWQKLNPTgaaPAGCAAH 246
Cdd:COG3055 180 ------GSGFSNTWT---TLAPLPTARAGHAAAVLGGKILVFGGESG--FSDEVEAYDPATNTWTALGEL---PTPRHGH 245

                       250       260
                ....*....|....*....|....
gi 33695109 247 SAVAMGKHVYIFGGMTPAGALDTM 270
Cdd:COG3055 246 AAVLTDGKVYVIGGETKPGVRTPL 269
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
85-269 8.74e-26

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 104.85  E-value: 8.74e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  85 PRYEHASFIPSctpDRIWVFGGANQSGNRNCLQVLNPETRTWTTpevTSPPPSPRTFHTSSAAIGNQLYVFGG-GERGAQ 163
Cdd:COG3055  12 PRSEAAAALLD---GKVYVAGGLSGGSASNSFEVYDPATNTWSE---LAPLPGPPRHHAAAVAQDGKLYVFGGfTGANPS 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109 164 PVQDTKLHVFDANTLTWSQpetLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAGC 243
Cdd:COG3055  86 STPLNDVYVYDPATNTWTK---LAPMPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQLAPLPTPRDHL 162

                       170       180
                ....*....|....*....|....*.
gi 33695109 244 AAhsAVAMGKHVYIFGGMTPAGALDT 269
Cdd:COG3055 163 AA--AVLPDGKILVIGGRNGSGFSNT 186
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
48-283 2.47e-24

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 100.62  E-value: 2.47e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  48 GKVFIVGGANPNRSFSDVHTMDLGKHQW----DLDTckglLPRYEHASFIPSctpDRIWVFGGANQSGNRNCLQ----VL 119
Cdd:COG3055  23 GKVYVAGGLSGGSASNSFEVYDPATNTWselaPLPG----PPRHHAAAVAQD---GKLYVFGGFTGANPSSTPLndvyVY 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109 120 NPETRTWTTpevTSPPPSPRTFHTsSAAIGNQLYVFGggerGAQPVQDTKLH-VFDANTLTWSQpetLGNPPSPRHGH-V 197
Cdd:COG3055  96 DPATNTWTK---LAPMPTPRGGAT-ALLLDGKIYVVG----GWDDGGNVAWVeVYDPATGTWTQ---LAPLPTPRDHLaA 164

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109 198 MVAAGTKLFIHGGLAGDRFYDdlhcidisdmKWQKLNPtgaAPAGCAAHSAVAMGKHVYIFGGMTpaGALDTMYQYHTEE 277
Cdd:COG3055 165 AVLPDGKILVIGGRNGSGFSN----------TWTTLAP---LPTARAGHAAAVLGGKILVFGGES--GFSDEVEAYDPAT 229


                ....*.
gi 33695109 278 QHWTLL 283
Cdd:COG3055 230 NTWTAL 235
PLN02193 PLN02193
nitrile-specifier protein
 126-280 2.81e-20

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 91.94  E-value: 2.81e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  126 WTTPEVTSPPPSPRTFHtSSAAIGNQLYVFGGGERGAQPVqDTKLHVFDANTLTWS-QPETLGNPPSPRHGHVMVAAGTK 204
Cdd:PLN02193 153 WIKVEQKGEGPGLRCSH-GIAQVGNKIYSFGGEFTPNQPI-DKHLYVFDLETRTWSiSPATGDVPHLSCLGVRMVSIGST 230

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 33695109  205 LFIHGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQHW 280
Cdd:PLN02193 231 LYVFGGRDASRQYNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVSATARLKTLDSYNIVDKKW 306
PLN02153 PLN02153
epithiospecifier protein
 136-279 1.57e-19

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 88.50  E-value: 1.57e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  136 PSPRTFHtSSAAIGNQLYVFGGgERGAQPVQDTKLHVFDANTLTWSQPETLGNPPS-PRHGHVMVAAGTKLFIHGGLAGD 214
Cdd:PLN02153  20 PGPRCSH-GIAVVGDKLYSFGG-ELKPNEHIDKDLYVFDFNTHTWSIAPANGDVPRiSCLGVRMVAVGTKLYIFGGRDEK 97

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 33695109  215 RFYDDLHCIDISDMKWQ---KLNPTGAaPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQH 279
Cdd:PLN02153  98 REFSDFYSYDTVKNEWTfltKLDEEGG-PEARTFHSMASDENHVYVFGGVSKGGLMKTPERFRTIEAY 164
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
125-283 3.00e-19

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 86.75  E-value: 3.00e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109 125 TWTTpevTSPPPSPRTfHTSSAAIGNQLYVFGGGERGAQPvqdTKLHVFDANTLTWSQpetLGNPP-SPRHGHVMVAAGT 203
Cdd:COG3055   2 TWSS---LPDLPTPRS-EAAAALLDGKVYVAGGLSGGSAS---NSFEVYDPATNTWSE---LAPLPgPPRHHAAAVAQDG 71

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109 204 KLFIHGGLAGD----RFYDDLHCIDISDMKWQKLNPtgaAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQH 279
Cdd:COG3055  72 KLYVFGGFTGAnpssTPLNDVYVYDPATNTWTKLAP---MPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGT 148


                ....
gi 33695109 280 WTLL 283
Cdd:COG3055 149 WTQL 152
PLN02193 PLN02193
nitrile-specifier protein
 9-283 1.03e-18

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 87.32  E-value: 1.03e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109    9 PGDKPRKATWYTLTVPGDSPCARVGHScsyLPPVGNakrgKVFIVGGA-NPNRSFSD-VHTMDLGKHQWDLDTCKGLLPr 86
Cdd:PLN02193 144 PSTPKLLGKWIKVEQKGEGPGLRCSHG---IAQVGN----KIYSFGGEfTPNQPIDKhLYVFDLETRTWSISPATGDVP- 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109   87 yeHASFIPSC---TPDRIWVFGGANQSGNRNCLQVLNPETRTWTTPEVTSPPPSPRTFHtSSAAIGNQLYVFGGGERGAq 163
Cdd:PLN02193 216 --HLSCLGVRmvsIGSTLYVFGGRDASRQYNGFYSFDTTTNEWKLLTPVEEGPTPRSFH-SMAADEENVYVFGGVSATA- 291

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  164 pvqdtKLHVFDANTL---TWSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFyDDLHCIDISDMKWQKLNPTGAAP 240
Cdd:PLN02193 292 -----RLKTLDSYNIvdkKWFHCSTPGDSFSIRGGAGLEVVQGKVWVVYGFNGCEV-DDVHYYDPVQDKWTQVETFGVRP 365

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 33695109  241 AGCAAHSAVAMGKHVYIFGG---------MTPAGALDTMYQYHTEEQHWTLL 283
Cdd:PLN02193 366 SERSVFASAAVGKHIVIFGGeiamdplahVGPGQLTDGTFALDTETLQWERL 417
PLN02153 PLN02153
epithiospecifier protein
 25-260 1.89e-14

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 73.48  E-value: 1.89e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109   25 GDSPCARVGHScsyLPPVGNakrgKVFIVGGA-NPNRSF-SDVHTMDLGKHQWDLDTCKGLLPRYEHASFIPSCTPDRIW 102
Cdd:PLN02153  17 GKGPGPRCSHG---IAVVGD----KLYSFGGElKPNEHIdKDLYVFDFNTHTWSIAPANGDVPRISCLGVRMVAVGTKLY 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  103 VFGGANQSGNRNCLQVLNPETRTWT--TPEVTSPPPSPRTFHtSSAAIGNQLYVFGGGERGAQPVQDTKLHVFDANTLT- 179
Cdd:PLN02153  90 IFGGRDEKREFSDFYSYDTVKNEWTflTKLDEEGGPEARTFH-SMASDENHVYVFGGVSKGGLMKTPERFRTIEAYNIAd 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  180 --WSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLA------GDRFYDD--LHCIDISDMKWQKLNPTGAAPAGCAAHSAV 249
Cdd:PLN02153 169 gkWVQLPDPGENFEKRGGAGFAVVQGKIWVVYGFAtsilpgGKSDYESnaVQFFDPASGKWTEVETTGAKPSARSVFAHA 248

                        250
                 ....*....|.
gi 33695109  250 AMGKHVYIFGG 260
Cdd:PLN02153 249 VVGKYIIIFGG 259
PLN02153 PLN02153
epithiospecifier protein
 187-298 6.94e-11

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 62.70  E-value: 6.94e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  187 GNPPSPRHGHVMVAAGTKLFIHGG-LAGDRFYD-DLHCIDISDMKWQKLNPTGAAPA-GCAAHSAVAMGKHVYIFGGMTP 263
Cdd:PLN02153  17 GKGPGPRCSHGIAVVGDKLYSFGGeLKPNEHIDkDLYVFDFNTHTWSIAPANGDVPRiSCLGVRMVAVGTKLYIFGGRDE 96

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 33695109  264 AGALDTMYQYHTEEQHWTLL-KFDTL-LPPGRLDHSM 298
Cdd:PLN02153  97 KREFSDFYSYDTVKNEWTFLtKLDEEgGPEARTFHSM 133
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
179-298 1.26e-10

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 61.33  E-value: 1.26e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109 179 TWSqpeTLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAhsAVAMGKHVYIF 258
Cdd:COG3055   2 TWS---SLPDLPTPRSEAAAALLDGKVYVAGGLSGGSASNSFEVYDPATNTWSELAPLPGPPRHHAA--AVAQDGKLYVF 76

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 33695109 259 GGMTPA----GALDTMYQYHTEEQHWTLLkfdTLLPPGRLDHSM 298
Cdd:COG3055  77 GGFTGAnpssTPLNDVYVYDPATNTWTKL---APMPTPRGGATA 117
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
13-174 5.49e-09

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 56.70  E-value: 5.49e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  13 PRKATWytlTVPGDSPCARVGHSCSYLPpvgnakRGKVFIVGGAN---PNRSFSDVHTMdlgkhqwdldtckgLLPRYEH 89
Cdd:COG3055 144 PATGTW---TQLAPLPTPRDHLAAAVLP------DGKILVIGGRNgsgFSNTWTTLAPL--------------PTARAGH 200

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  90 ASFIPSctpDRIWVFGGanQSGNRNCLQVLNPETRTWTTpevTSPPPSPRTFHTSsAAIGNQLYVFGGG-ERGAQPVQDT 168
Cdd:COG3055 201 AAAVLG---GKILVFGG--ESGFSDEVEAYDPATNTWTA---LGELPTPRHGHAA-VLTDGKVYVIGGEtKPGVRTPLVT 271


                ....*.
gi 33695109 169 KLHVFD 174
Cdd:COG3055 272 SAEVYD 277
PRK14131 PRK14131
N-acetylneuraminate epimerase;
145-260 6.41e-09

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 56.95  E-value: 6.41e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  145 SAAIGNQLYVfGGGERGaqpvqdTKLHVFDANTLT--WSQPETLgnPPSPRHGHVMVAAGTKLFIHGGL------AGDRF 216
Cdd:PRK14131  34 GAIDNNTVYV-GLGSAG------TSWYKLDLNAPSkgWTKIAAF--PGGPREQAVAAFIDGKLYVFGGIgktnseGSPQV 104

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 33695109  217 YDDLHCIDISDMKWQKLNPTgaAPAGCAAHSAVAM-GKHVYIFGG 260
Cdd:PRK14131 105 FDDVYKYDPKTNSWQKLDTR--SPVGLAGHVAVSLhNGKAYITGG 147
PRK14131 PRK14131
N-acetylneuraminate epimerase;
41-272 1.02e-07

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 53.10  E-value: 1.02e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109   41 PVGNAKRGKVFIVGG------ANPNRSFSDVHTMDLGKHQWD-LDTC--KGLLpryEHASFIPSctPDRIWVFGGANQS- 110
Cdd:PRK14131  78 AVAAFIDGKLYVFGGigktnsEGSPQVFDDVYKYDPKTNSWQkLDTRspVGLA---GHVAVSLH--NGKAYITGGVNKNi 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  111 ----------------------------------GNRNCLqVLNPETRTWTTPEVTsppPSPRTFHTSSAAIGNQLYVFG 156
Cdd:PRK14131 153 fdgyfedlaaagkdktpkdkindayfdkkpedyfFNKEVL-SYDPSTNQWKNAGES---PFLGTAGSAVVIKGNKLWLIN 228

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  157 G----GERGAQpvqdTKLHVFDANTLTWSQPETLgnPPSPR---------------HGHVMVAAGT------------KL 205
Cdd:PRK14131 229 GeikpGLRTDA----VKQGKFTGNNLKWQKLPDL--PPAPGgssqegvagafagysNGVLLVAGGAnfpgarenyqngKL 302

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 33695109  206 FIHGGLAgDRFYDDLHCIDisDMKWQKLnptGAAPAGCAAHSAVAMGKHVYIFGGMTPAG-ALDTMYQ 272
Cdd:PRK14131 303 YAHEGLK-KSWSDEIYALV--NGKWQKV---GELPQGLAYGVSVSWNNGVLLIGGETAGGkAVSDVTL 364
PLN02153 PLN02153
epithiospecifier protein
 17-221 5.63e-07

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 50.76  E-value: 5.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109   17 TWYTLTVPGDSPcaRVGHSCSYLPPVGNakrgKVFIVGGANPNRSFSDVHTMDLGKHQW----DLDTCKGLLPRYEHASf 92
Cdd:PLN02153  61 TWSIAPANGDVP--RISCLGVRMVAVGT----KLYIFGGRDEKREFSDFYSYDTVKNEWtfltKLDEEGGPEARTFHSM- 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109   93 ipSCTPDRIWVFGGANQSG------------------------------------------------------------- 111
Cdd:PLN02153 134 --ASDENHVYVFGGVSKGGlmktperfrtieayniadgkwvqlpdpgenfekrggagfavvqgkiwvvygfatsilpggk 211

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  112 ---NRNCLQVLNPETRTWTTPEVTSPPPSPRTFHtSSAAIGNQLYVFGG-------GERGAQPVQDTKlHVFDANTLTWS 181
Cdd:PLN02153 212 sdyESNAVQFFDPASGKWTEVETTGAKPSARSVF-AHAVVGKYIIIFGGevwpdlkGHLGPGTLSNEG-YALDTETLVWE 289

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 33695109  182 QPETLGNPPSPRHGHVMVAA---GTK-LFIHGG-LAGDRFYDDLH 221
Cdd:PLN02153 290 KLGECGEPAMPRGWTAYTTAtvyGKNgLLMHGGkLPTNERTDDLY 334
PLN02153 PLN02153
epithiospecifier protein
 81-293 1.20e-06

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 49.98  E-value: 1.20e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109   81 KGLLPRYEHASfipSCTPDRIWVFGG---ANQSGNRNcLQVLNPETRTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGG 157
Cdd:PLN02153  18 KGPGPRCSHGI---AVVGDKLYSFGGelkPNEHIDKD-LYVFDFNTHTWSIAPANGDVPRISCLGVRMVAVGTKLYIFGG 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  158 GErgaQPVQDTKLHVFDANTLTW---SQPETLGNPPSpRHGHVMVAAGTKLFIHGGLAG-------DRFyDDLHCIDISD 227
Cdd:PLN02153  94 RD---EKREFSDFYSYDTVKNEWtflTKLDEEGGPEA-RTFHSMASDENHVYVFGGVSKgglmktpERF-RTIEAYNIAD 168

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 33695109  228 MKWQKL-NPTGAAPAGCAAHSAVAMGKHVYIFGGMT---PAGALD----TMYQYHTEEQHWTLLKFDTLLPPGR 293
Cdd:PLN02153 169 GKWVQLpDPGENFEKRGGAGFAVVQGKIWVVYGFATsilPGGKSDyesnAVQFFDPASGKWTEVETTGAKPSAR 242
Kelch_3 pfam13415
Galactose oxidase, central domain;
149-201 1.26e-06

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 44.97  E-value: 1.26e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 33695109   149 GNQLYVFGGGERGAQPVqDTKLHVFDANTLTWsqpETLGNPPSPRHGHVMVAA 201
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTR-LNDLYVYDLDTNTW---TQIGDLPPPRSGHSATYI 49
Kelch_3 pfam13415
Galactose oxidase, central domain;
99-147 3.30e-06

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 43.82  E-value: 3.30e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 33695109    99 DRIWVFGGANQSGNR--NCLQVLNPETRTWTTpevTSPPPSPRTFHTSSAA 147
Cdd:pfam13415   2 DKLYIFGGLGFDGQTrlNDLYVYDLDTNTWTQ---IGDLPPPRSGHSATYI 49
Kelch_6 pfam13964
Kelch motif;
138-193 8.24e-06

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 42.71  E-value: 8.24e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 33695109   138 PRTFHtSSAAIGNQLYVFGGGERGAQPVQdtKLHVFDANTLTWsqpETLGNPPSPR 193
Cdd:pfam13964   1 PRTFH-SVVSVGGYIYVFGGYTNASPALN--KLEVYNPLTKSW---EELPPLPTPR 50
PHA03098 PHA03098
kelch-like protein; Provisional
 41-230 1.46e-05

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 46.68  E-value: 1.46e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109   41 PVGNAKRGKVFIVGGANPNRSFSDVHTMDLGKHQWDLDTcKGLLPRYEHASFIpscTPDRIWVFGGANQSG-NRNCLQVL 119
Cdd:PHA03098 336 PGVTVFNNRIYVIGGIYNSISLNTVESWKPGESKWREEP-PLIFPRYNPCVVN---VNNLIYVIGGISKNDeLLKTVECF 411

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  120 NPETRTWTTPEvtsppPSPRTFHTSSAAI-GNQLYVFGGGERGAQPVQDTKLHVFDANTLTWSQPETLGNppsPRHGHVM 198
Cdd:PHA03098 412 SLNTNKWSKGS-----PLPISHYGGCAIYhDGKIYVIGGISYIDNIKVYNIVESYNPVTNKWTELSSLNF---PRINASL 483

                        170       180       190
                 ....*....|....*....|....*....|..
gi 33695109  199 VAAGTKLFIHGGLAGDRFYDDLHCIDISDMKW 230
Cdd:PHA03098 484 CIFNNKIYVVGGDKYEYYINEIEVYDDKTNTW 515
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 243-283 2.53e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 41.06  E-value: 2.53e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 33695109   243 CAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQHWTLL 283
Cdd:pfam01344   2 RSGAGVVVVGGKIYVIGGFDGNQSLNSVEVYDPETNTWSKL 42
PHA03098 PHA03098
kelch-like protein; Provisional
 99-301 1.36e-04

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 43.60  E-value: 1.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109   99 DRIWVFGGANQSGNR-NCLQVLNPETRTWTT-PEVTSPPPSPrtfhtSSAAIGNQLYVFGGgERGAQPVQDTKLHVFDAN 176
Cdd:PHA03098 295 NVIYFIGGMNKNNLSvNSVVSYDTKTKSWNKvPELIYPRKNP-----GVTVFNNRIYVIGG-IYNSISLNTVESWKPGES 368

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695109  177 TltWSQPETLgnpPSPRHGHVMVAAGTKLFIHGGLA-GDRFYDDLHCIDISDMKWQKLNPTgaaPAGCAAHSAVAMGKHV 255
Cdd:PHA03098 369 K--WREEPPL---IFPRYNPCVVNVNNLIYVIGGISkNDELLKTVECFSLNTNKWSKGSPL---PISHYGGCAIYHDGKI 440

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 33695109  256 YIFGGMTPA---GALDTMYQYHTEEQHWTLLKfdTLLPPgRLDHSMCII 301
Cdd:PHA03098 441 YVIGGISYIdniKVYNIVESYNPVTNKWTELS--SLNFP-RINASLCIF 486
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 192-235 1.55e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 38.75  E-value: 1.55e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 33695109   192 PRHGHVMVAAGTKLFIHGGLAGDRFYDDLHCIDISDMKWQKLNP 235
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQSLNSVEVYDPETNTWSKLPS 44
Kelch_4 pfam13418
Galactose oxidase, central domain;
138-191 1.67e-04

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 38.75  E-value: 1.67e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 33695109   138 PRTFHTSSAAIGNQLYVFGGgeRGAQPVQDTKLHVFDANTLTWSQpetLGNPPS 191
Cdd:pfam13418   1 PRAYHTSTSIPDDTIYLFGG--EGEDGTLLSDLWVFDLSTNEWTR---LGSLPS 49
Kelch_4 pfam13418
Galactose oxidase, central domain;
85-136 3.46e-04

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 37.98  E-value: 3.46e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 33695109    85 PRYEHASFipSCTPDRIWVFGGANQSGNR-NCLQVLNPETRTWTTpeVTSPPP 136
Cdd:pfam13418   1 PRAYHTST--SIPDDTIYLFGGEGEDGTLlSDLWVFDLSTNEWTR--LGSLPS 49
Kelch_6 pfam13964
Kelch motif;
85-139 4.46e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 37.70  E-value: 4.46e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 33695109    85 PRYEHASFIPSctpDRIWVFGGANQSGNR-NCLQVLNPETRTWttpEVTSPPPSPR 139
Cdd:pfam13964   1 PRTFHSVVSVG---GYIYVFGGYTNASPAlNKLEVYNPLTKSW---EELPPLPTPR 50
Kelch_4 pfam13418
Galactose oxidase, central domain;
192-233 5.50e-04

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 37.59  E-value: 5.50e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 33695109   192 PRHGHVMVA-AGTKLFIHGGLAGD-RFYDDLHCIDISDMKWQKL 233
Cdd:pfam13418   1 PRAYHTSTSiPDDTIYLFGGEGEDgTLLSDLWVFDLSTNEWTRL 44
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 190-221 5.89e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 37.16  E-value: 5.89e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 33695109   190 PSPRHGHVMVAAGTKLFIHGGLAGDR--FYDDLH 221
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEgqPSDDVY 34
PLN02772 PLN02772
guanylate kinase
 144-214 8.79e-04

guanylate kinase


Pssm-ID: 215414 [Multi-domain]  Cd Length: 398  Bit Score: 40.98  E-value: 8.79e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 33695109  144 SSAAIGNQLYVFGGGERGAQPVQDTKLhvFDANTLTWSQPETLGNPPSPRHGH--VMVAAGTKLFIHGGLAGD 214
Cdd:PLN02772  29 TSVTIGDKTYVIGGNHEGNTLSIGVQI--LDKITNNWVSPIVLGTGPKPCKGYsaVVLNKDRILVIKKGSAPD 99
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 240-276 9.97e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 33.69  E-value: 9.97e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 33695109   240 PAGCAAHSAVAMGKHVYIFGGMTPAG--ALDTMYQYHTE 276
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEgqPSDDVYVLSLP 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH