|
Name |
Accession |
Description |
Interval |
E-value |
| CCCAP |
pfam15964 |
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ... |
6-706 |
0e+00 |
|
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.
Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 898.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 6 ENSTLEEILGQYQRSLREHASRSIHQLTCALKEGDVTIGEDAPNLSFSTSVGNEDARTAWPELQQSHAVNQLKDLLRQQA 85
Cdd:pfam15964 1 GNSTLEESLGQYQRSLRERANRSIHQLKCALHESDSTISEDEQEESLSSVVQNEDSGSPWSELQHSHAVNQLKALLQQQT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 86 DKESEVSPsRRRKMSPLRSLEHEETNMPTMHDLVHTINDQSQYIHHLEAEVKFCKEELSGMKNKIQVVVLENEGLQQQLK 165
Cdd:pfam15964 81 KKENELSP-RRRKLSPSRTSEDESSSLPTVHDLVPIINDQSQYIHHLEAEVKFCKEELSEMKQRVQVVVLENEKLQQELK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 166 SQRQEETLREQTLLDASGNMHNSWITtGEDSGVGETSKRPFSHDNADFGKAASAGE----QLELEKLKLTYEEKCEIEES 241
Cdd:pfam15964 160 SQTQEETLREQTLLDSSGNMQNSWCT-PEDSRVHQTSKRPASHNLAERLKSATTGEdekwRLELEKLKLLYEAKTEVLES 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 242 QLKFLRNDLAEYQRTCEDLKEQLKHKEFLLAANTCNRVGGLCLKCAQHEAVLSQTHTNVHMQTIERLVKERDDLMSALVS 321
Cdd:pfam15964 239 QVKSLRKDLAESQKTCEDLKERLKHKESLVAASTSSRVGGLCLKCAQHEAVLAQTHTNVHMQTIERLTKERDDLMSALVS 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 322 VRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQQEKRAIEKDMMKKEITKER 401
Cdd:pfam15964 319 VRSSLAEAQQRESSAYEQVKQAVQMTEEANFEKTKALIQCEQLKSELERQKERLEKELASQQEKRAQEKEALRKEMKKER 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 402 EYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEKEHREFRAK 481
Cdd:pfam15964 399 EELGATMLALSQNVAQLEAQVEKVTREKNSLVSQLEEAQKQLASQEMDVTKVCGEMRYQLNQTKMKKDEAEKEHREYRTK 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 482 TNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQ 561
Cdd:pfam15964 479 TGRQLEIKDQEIEKLGLELSESKQRLEQAQQDAARAREECLKLTELLGESEHQLHLTRLEKESIQQSFSNEAKAQALQAQ 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 562 QREQELTQKIQQMEAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRR 641
Cdd:pfam15964 559 QREQELTQKMQQMEAQHDKTVNEQYSLLTSQNTFIAKLKEECCTLAKKLEEITQKSRSEVEQLSQEKEYLQDRLEKLQKR 638
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 28269672 642 NEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQLP 706
Cdd:pfam15964 639 NEELEEQCVQHGRMHERMKQRLRQLDKHCQATAQQLVQLLSKQNQLFKERQNLTEEVQSLRSQVP 703
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
397-705 |
1.86e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 61.23 E-value: 1.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 397 ITKEREYMGSKMLILSQNIAQLEAQVEKVT---KEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEK 473
Cdd:TIGR02168 661 ITGGSAKTNSSILERRREIEELEEKIEELEekiAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 474 EHREFRAKTNR----------DLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKD 543
Cdd:TIGR02168 741 EVEQLEERIAQlskelteleaEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAA 820
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 544 SiQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEqyllLTSQNTFLTKLKEECCTLAKKLEQISQ---KTRSE 620
Cdd:TIGR02168 821 N-LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE----IEELEELIEELESELEALLNERASLEEalaLLRSE 895
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 621 IAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLdkHSQATAQQLVQL---LSKQNQLLLERQSLSEE 697
Cdd:TIGR02168 896 LEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYSLTLeeaEALENKIEDDEEEARRR 973
|
....*...
gi 28269672 698 VDRLRTQL 705
Cdd:TIGR02168 974 LKRLENKI 981
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
365-693 |
3.46e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 60.34 E-value: 3.46e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 365 RKELERQAERLEK--ELASQQEKRAIE--------KDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAIN 434
Cdd:COG1196 202 LEPLERQAEKAERyrELKEELKELEAEllllklreLEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 435 QLEEIQSQLASREMDVtkvcgemryqlnktnmEKDEAEKEHREFRAKTNRdleikdQEIEKLRIELDESKQHLEQEQQKA 514
Cdd:COG1196 282 ELEEAQAEEYELLAEL----------------ARLEQDIARLEERRRELE------ERLEELEEELAELEEELEELEEEL 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 515 ALAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTsqnt 594
Cdd:COG1196 340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER---- 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 595 fLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRytydKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATA 674
Cdd:COG1196 416 -LERLEEELEELEEALAELEEEEEEEEEALEEAAE----EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
|
330
....*....|....*....
gi 28269672 675 QQLVQLLSKQNQLLLERQS 693
Cdd:COG1196 491 ARLLLLLEAEADYEGFLEG 509
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
411-705 |
2.11e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 57.64 E-value: 2.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 411 LSQNIAQLEAQVEKVTK-EKISAinQLEEIQSQLASREMDvtkvcgEMRYQLNKTNMEKDEAEKEHREFRAKtnrdLEIK 489
Cdd:COG1196 198 LERQLEPLERQAEKAERyRELKE--ELKELEAELLLLKLR------ELEAELEELEAELEELEAELEELEAE----LAEL 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 490 DQEIEKLRIELDESKQHLEQEQQKAALAREEclrltelLGESEHQLHLTRQEKDSIQQsfskeakaqalqaqqREQELTQ 569
Cdd:COG1196 266 EAELEELRLELEELELELEEAQAEEYELLAE-------LARLEQDIARLEERRRELEE---------------RLEELEE 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 570 KIQQMEAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQc 649
Cdd:COG1196 324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL- 402
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 28269672 650 VQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQL 705
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
338-670 |
9.49e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.83 E-value: 9.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 338 EQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELAsQQEKRAIEKDMMKKEITKEREYMGSKMLILSQNIAQ 417
Cdd:TIGR02168 680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE-ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 418 LEAQVEKVTKEKISAINQLEEIQSQLASREMDVTkvcgEMRYQLNKTNMEKDEAEKEH---REFRAKTNRDLEIKDQEIE 494
Cdd:TIGR02168 759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIE----QLKEELKALREALDELRAELtllNEEAANLRERLESLERRIA 834
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 495 KLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQQsfskeakaQALQAQQREQELTQKIQQM 574
Cdd:TIGR02168 835 ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEE--------ALALLRSELEELSEELREL 906
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 575 EAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGR 654
Cdd:TIGR02168 907 ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGP 986
|
330 340
....*....|....*....|...
gi 28269672 655 VH-------ETMKQRLRQLDKHS 670
Cdd:TIGR02168 987 VNlaaieeyEELKERYDFLTAQK 1009
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
363-666 |
1.09e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.45 E-value: 1.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 363 QLRKeLERQAERLEKELASQQEKRAIEKDMMKKEITKEREymgsKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQ 442
Cdd:TIGR02168 201 QLKS-LERQAEKAERYKELKAELRELELALLVLRLEELRE----ELEELQEELKEAEEELEELTAELQELEEKLEELRLE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 443 LASREMDVTKVCGEMrYQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECL 522
Cdd:TIGR02168 276 VSELEEEIEELQKEL-YALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 523 RLTELLGESEHQ---LHLTRQEKDSIQQSFSKEakaqALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTSQNTFLTKL 599
Cdd:TIGR02168 355 SLEAELEELEAEleeLESRLEELEEQLETLRSK----VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL 430
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 28269672 600 KEeccTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQL 666
Cdd:TIGR02168 431 EE---AELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL 494
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
366-648 |
1.38e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.07 E-value: 1.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 366 KELERQAERLEKELASQQEKraiekdmmKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAIN-QLEEIQSQLA 444
Cdd:TIGR02169 233 EALERQKEAIERQLASLEEE--------LEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKeKIGELEAEIA 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 445 SREMDVTKVCGEMR---YQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQ---EIEKLRIELDESKQHLEQEQQKAALAR 518
Cdd:TIGR02169 305 SLERSIAEKERELEdaeERLAKLEAEIDKLLAEIEELEREIEEERKRRDKlteEYAELKEELEDLRAELEEVDKEFAETR 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 519 EEclrltelLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREqELTQKIQQMEAQHDKTENEqyllltsqntfLTK 598
Cdd:TIGR02169 385 DE-------LKDYREKLEKLKREINELKRELDRLQEELQRLSEELA-DLNAAIAGIEAKINELEEE-----------KED 445
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 28269672 599 LKEECCTLAKKLEQISQ---KTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQ 648
Cdd:TIGR02169 446 KALEIKKQEWKLEQLAAdlsKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQ 498
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
287-566 |
5.61e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.02 E-value: 5.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 287 AQHEAVLSQTHTNVHMQTIERLVKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRK 366
Cdd:COG1196 244 LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 367 ELERQAERLEKELASQQEKRAIEKDMMKKEITKEreymgskmlilsQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASR 446
Cdd:COG1196 324 ELAELEEELEELEEELEELEEELEEAEEELEEAE------------AELAEAEEALLEAEAELAEAEEELEELAEELLEA 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 447 EMDvtkvcgemRYQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTE 526
Cdd:COG1196 392 LRA--------AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 28269672 527 LLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQE 566
Cdd:COG1196 464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
303-584 |
7.40e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.75 E-value: 7.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 303 QTIERLVKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEkELASQ 382
Cdd:TIGR02168 712 EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE-ELEAQ 790
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 383 QEKRAIEKDMMKKEITKEREYMGSkmliLSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMryqln 462
Cdd:TIGR02168 791 IEQLKEELKALREALDELRAELTL----LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI----- 861
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 463 ktNMEKDEAEKEHREFRAKTNRdLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEK 542
Cdd:TIGR02168 862 --EELEELIEELESELEALLNE-RASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI 938
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 28269672 543 DSIQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENE 584
Cdd:TIGR02168 939 DNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
411-648 |
4.53e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.38 E-value: 4.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 411 LSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMdvtkvcgemryQLNKTNMEkdeaekehrefRAKTNRDLEIKD 490
Cdd:COG4942 32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALAR-----------RIRALEQE-----------LAALEAELAELE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 491 QEIEKLRIELDESKQHLEQeqQKAALAREECLRLTELLGESEHQLHLTRQEKdsIQQSFSKEAKAQALQAQQREQELTQK 570
Cdd:COG4942 90 KEIAELRAELEAQKEELAE--LLRALYRLGRQPPLALLLSPEDFLDAVRRLQ--YLKYLAPARREQAEELRADLAELAAL 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 28269672 571 IQQMEAQHDKTEnEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQ 648
Cdd:COG4942 166 RAELEAERAELE-ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
303-647 |
7.36e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.68 E-value: 7.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 303 QTIERLVKERDDLMsalvsvRSSLADTQQREASAYEQVKQVlqisEEANFEKTKALIQCDQLRKELE---RQAERLEKEL 379
Cdd:TIGR02169 198 QQLERLRREREKAE------RYQALLKEKREYEGYELLKEK----EALERQKEAIERQLASLEEELEkltEEISELEKRL 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 380 ASQQEKRaiekdmmkKEITKEREYMGS-KMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMdvtkvcgemr 458
Cdd:TIGR02169 268 EEIEQLL--------EELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA---------- 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 459 yQLNKTNMEKDEAEKEHREFRaktnRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREEclrltelLGESEHQLHLT 538
Cdd:TIGR02169 330 -EIDKLLAEIEELEREIEEER----KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE-------LKDYREKLEKL 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 539 RQEKDSIQQSFSKeakaqalqAQQREQELTQKIQQMEAQHDKTENEqyllltsqntfLTKLKEECCTLAKKLEQISQKTR 618
Cdd:TIGR02169 398 KREINELKRELDR--------LQEELQRLSEELADLNAAIAGIEAK-----------INELEEEKEDKALEIKKQEWKLE 458
|
330 340
....*....|....*....|....*....
gi 28269672 619 SEIAQLSQEKRYTYDKLGKLQRRNEELEE 647
Cdd:TIGR02169 459 QLAADLSKYEQELYDLKEEYDRVEKELSK 487
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
420-705 |
8.10e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 49.28 E-value: 8.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 420 AQVEKVTKEKISAINQLEEIQSQLASremdVTKVCGEMRYQLNKTNMEKDEAEKehreFRAKTNrdlEIKDQEIEKLRIE 499
Cdd:TIGR02168 165 AGISKYKERRKETERKLERTRENLDR----LEDILNELERQLKSLERQAEKAER----YKELKA---ELRELELALLVLR 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 500 LDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTR---QEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEA 576
Cdd:TIGR02168 234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRlevSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 577 QHDKTENEQYLLLTSQNTfLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRytydKLGKLQRRNEELEEQcvqhgrvH 656
Cdd:TIGR02168 314 LERQLEELEAQLEELESK-LDELAEELAELEEKLEELKEELESLEAELEELEA----ELEELESRLEELEEQ-------L 381
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 28269672 657 ETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQL 705
Cdd:TIGR02168 382 ETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL 430
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
322-477 |
1.75e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 47.85 E-value: 1.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 322 VRSSLADTQQREASayEQVKQVLQISE-EANFEKTKALIQC----DQLRKELERQAERLEKELASQQEKRAIEKDMMKKE 396
Cdd:PRK12704 24 VRKKIAEAKIKEAE--EEAKRILEEAKkEAEAIKKEALLEAkeeiHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRK 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 397 ---ITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIqSQLAS---REMDVTKVCGEMRYQ----LNKTNM 466
Cdd:PRK12704 102 lelLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERI-SGLTAeeaKEILLEKVEEEARHEaavlIKEIEE 180
|
170
....*....|..
gi 28269672 467 E-KDEAEKEHRE 477
Cdd:PRK12704 181 EaKEEADKKAKE 192
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
333-665 |
2.54e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 47.66 E-value: 2.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 333 EASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERL---EKELASQQEKRAIEKDMMKKEITKEREYMGSKML 409
Cdd:pfam02463 160 EEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLkeqAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERI 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 410 ILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEKEHREFRAKTNRDLEIK 489
Cdd:pfam02463 240 DLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKES 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 490 DQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQ 569
Cdd:pfam02463 320 EKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELEL 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 570 KIQQMEAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQC 649
Cdd:pfam02463 400 KSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL 479
|
330
....*....|....*.
gi 28269672 650 VQHGRVHETMKQRLRQ 665
Cdd:pfam02463 480 VKLQEQLELLLSRQKL 495
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
480-701 |
2.62e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.76 E-value: 2.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 480 AKTNRDLEIKDQEIEKLRIELDESKQHLEQ--------EQQKAALAREECLRLTELLGE---SEHQLHLTRQEKDSIQQS 548
Cdd:TIGR02169 173 EKALEELEEVEENIERLDLIIDEKRQQLERlrrerekaERYQALLKEKREYEGYELLKEkeaLERQKEAIERQLASLEEE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 549 FSKeAKAQALQAQQREQELTQKIQQMEAQ-HDKTENEQYLL------LTSQNTFLTKLKEECCTLAKKLEQISQKTRSEI 621
Cdd:TIGR02169 253 LEK-LTEEISELEKRLEEIEQLLEELNKKiKDLGEEEQLRVkekigeLEAEIASLERSIAEKERELEDAEERLAKLEAEI 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 622 AQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRL 701
Cdd:TIGR02169 332 DKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL 411
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
414-705 |
1.26e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.44 E-value: 1.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 414 NIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMryqlnktnmekDEAEKEHREFRaktnRDLEIKDQEI 493
Cdd:TIGR02169 668 FSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQEL-----------SDASRKIGEIE----KEIEQLEQEE 732
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 494 EKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEakaqalqaqqREQELTQKIQQ 573
Cdd:TIGR02169 733 EKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHS----------RIPEIQAELSK 802
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 574 MEAQHdkTENEQYLLLTSQNTfltklkeecctlaKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHG 653
Cdd:TIGR02169 803 LEEEV--SRIEARLREIEQKL-------------NRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELE 867
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 28269672 654 RVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQL 705
Cdd:TIGR02169 868 EELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
303-519 |
1.26e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.68 E-value: 1.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 303 QTIERLVKERDDLMSAlvsvRSSLADT-QQREA-----SAYEQVKQVLQISEEANFEKTKALIQCDQLRKEL-ERQAERL 375
Cdd:COG4913 225 EAADALVEHFDDLERA----HEALEDArEQIELlepirELAERYAAARERLAELEYLRAALRLWFAQRRLELlEAELEEL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 376 EKELASQQEKRAIEKDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVT---K 452
Cdd:COG4913 301 RAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPasaE 380
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28269672 453 VCGEMRYQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQ-----HLEQEQQKAALARE 519
Cdd:COG4913 381 EFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERrksniPARLLALRDALAEA 452
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
366-704 |
1.29e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.44 E-value: 1.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 366 KELERQAERLEKELASQQ----EKRAIEKDMMKK--EITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEI 439
Cdd:TIGR02169 684 EGLKRELSSLQSELRRIEnrldELSQELSDASRKigEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKEL 763
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 440 QSQLASREMDVTKvcgemrYQLNKTNMEKDEAEKEHREFRAKTnrdleikdQEIEKLRIELDESKQHLEQE----QQKAA 515
Cdd:TIGR02169 764 EARIEELEEDLHK------LEEALNDLEARLSHSRIPEIQAEL--------SKLEEEVSRIEARLREIEQKlnrlTLEKE 829
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 516 LAREECLRLTELLGESEHQLHLTRQEKDSIQ------QSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLL 589
Cdd:TIGR02169 830 YLEKEIQELQEQRIDLKEQIKSIEKEIENLNgkkeelEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELE 909
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 590 TSQNTFLTKLKEECCTLAKKLEQISQKTRsEIAQLSQEKRYTYDkLGKLQRRNEELEEQCVQHGRVHetmkqrLRQLDKH 669
Cdd:TIGR02169 910 AQIEKKRKRLSELKAKLEALEEELSEIED-PKGEDEEIPEEELS-LEDVQAELQRVEEEIRALEPVN------MLAIQEY 981
|
330 340 350
....*....|....*....|....*....|....*
gi 28269672 670 SQaTAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQ 704
Cdd:TIGR02169 982 EE-VLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
479-705 |
2.57e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 2.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 479 RAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQqsfsKEAKAQAL 558
Cdd:COG4942 22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE----KEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 559 QAQQREQELTQKIQQMEAQHdktENEQYLLLTSQNTFLTKLKeecctLAKKLEQISQKTRSEIAQLSQEKRytydklgKL 638
Cdd:COG4942 98 ELEAQKEELAELLRALYRLG---RQPPLALLLSPEDFLDAVR-----RLQYLKYLAPARREQAEELRADLA-------EL 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 28269672 639 QRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQL 705
Cdd:COG4942 163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
303-520 |
3.70e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 3.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 303 QTIERLVKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQ 382
Cdd:COG4942 34 QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRAL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 383 QEKRAIEKDMMK------KEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLAsremdvtkvcge 456
Cdd:COG4942 114 YRLGRQPPLALLlspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA------------ 181
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 28269672 457 mryQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREE 520
Cdd:COG4942 182 ---ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
329-702 |
5.63e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.42 E-value: 5.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 329 TQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEkelasqqEKRAIEKDMMKKEITKEREYMGSKM 408
Cdd:TIGR00618 223 VLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIE-------ELRAQEAVLEETQERINRARKAAPL 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 409 LILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVcGEMRYQLNKTNMEKDEAEKEHREfrAKTNRDLEI 488
Cdd:TIGR00618 296 AAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSI-EEQRRLLQTLHSQEIHIRDAHEV--ATSIREISC 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 489 KDQEIEKLRIELDESKQHLEQEQQKAA-----LAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQR 563
Cdd:TIGR00618 373 QQHTLTQHIHTLQQQKTTLTQKLQSLCkeldiLQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQ 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 564 EQELTQKIQQMEAQHDKTENEQyllLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQ--EKRYTYDKLGKLQRR 641
Cdd:TIGR00618 453 CEKLEKIHLQESAQSLKEREQQ---LQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHpnPARQDIDNPGPLTRR 529
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 28269672 642 NEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLR 702
Cdd:TIGR00618 530 MQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQ 590
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
291-700 |
7.04e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 43.29 E-value: 7.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 291 AVLSQTHTNVHMQTIERLVKERddlmsaLVSVRSSLADTQQREASAYEQVKQVlqiSEEANFEKTKALIQCDQLRKELER 370
Cdd:pfam12128 256 AELRLSHLHFGYKSDETLIASR------QEERQETSAELNQLLRTLDDQWKEK---RDELNGELSAADAAVAKDRSELEA 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 371 QAERLEKELASQQEKRAIEKDMMK------KEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAIN-----QLEEI 439
Cdd:pfam12128 327 LEDQHGAFLDADIETAAADQEQLPswqselENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKdklakIREAR 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 440 QSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEKEHRE-------------FRAKTNRDLEIKDQEIEKLRIEL------ 500
Cdd:pfam12128 407 DRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSrlgelklrlnqatATPELLLQLENFDERIERAREEQeaanae 486
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 501 ---------------DESKQHLEQEQQKAALAREECLRLTELLGESEHQL-HLTRQEKDSIQQSFSKEAKAQALQAQQRE 564
Cdd:pfam12128 487 verlqselrqarkrrDQASEALRQASRRLEERQSALDELELQLFPQAGTLlHFLRKEAPDWEQSIGKVISPELLHRTDLD 566
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 565 QELTQKIQQMEA-------QHDKTENEQYLLLTSQntfltkLKEEcctlAKKLEQISQKTRSEIAQLSQEKRYTYDKLGK 637
Cdd:pfam12128 567 PEVWDGSVGGELnlygvklDLKRIDVPEWAASEEE------LRER----LDKAEEALQSAREKQAAAEEQLVQANGELEK 636
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28269672 638 LQRRnEELEEQCVQHGR--------VHETMKQRL-RQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDR 700
Cdd:pfam12128 637 ASRE-ETFARTALKNARldlrrlfdEKQSEKDKKnKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKE 707
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
233-582 |
7.30e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 43.11 E-value: 7.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 233 EEKCEIEESQLKFLRNDLAEYQRTCEDLKEQLKHKEFLLAAntcnrvgGLCLKCAQheavlsQTHTNVHMQTIERLVKER 312
Cdd:PRK02224 411 EDFLEELREERDELREREAELEATLRTARERVEEAEALLEA-------GKCPECGQ------PVEGSPHVETIEEDRERV 477
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 313 DDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEAnfEKTKALIQ-CDQLRKELERQAERLEkELASQQEKRAIEKD 391
Cdd:PRK02224 478 EELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLE--ERREDLEElIAERRETIEEKRERAE-ELRERAAELEAEAE 554
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 392 MMKKEITKEREYMGSKMlilsQNIAQLEAQVEKVTkekiSAINQLEEIQSQLASREmdvtkvcgemryqlnktnmEKDEA 471
Cdd:PRK02224 555 EKREAAAEAEEEAEEAR----EEVAELNSKLAELK----ERIESLERIRTLLAAIA-------------------DAEDE 607
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 472 EKEHREFRAKTNrdlEIKDQEIEKLRiELDESKQHLEQEQQKAAL--AREECLRLTELLGESEHQLHLTRQEKDSIQQSF 549
Cdd:PRK02224 608 IERLREKREALA---ELNDERRERLA-EKRERKRELEAEFDEARIeeAREDKERAEEYLEQVEEKLDELREERDDLQAEI 683
|
330 340 350
....*....|....*....|....*....|....*
gi 28269672 550 SKEAKAQALQAQQREQ--ELTQKIQQMEAQHDKTE 582
Cdd:PRK02224 684 GAVENELEELEELRERreALENRVEALEALYDEAE 718
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
479-698 |
1.17e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.31 E-value: 1.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 479 RAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQK---------AALAREECLRLTELLGESEHQLHLTRQEKDSIQQSF 549
Cdd:COG3206 170 REEARKALEFLEEQLPELRKELEEAEAALEEFRQKnglvdlseeAKLLLQQLSELESQLAEARAELAEAEARLAALRAQL 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 550 SKEAKAQALQAQQRE-QELTQKIQQMEAQhdktENEQYLLLTSQNTFLTKLKEEcctLAKKLEQISQKTRSEIAQLSQEK 628
Cdd:COG3206 250 GSGPDALPELLQSPViQQLRAQLAELEAE----LAELSARYTPNHPDVIALRAQ---IAALRAQLQQEAQRILASLEAEL 322
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 629 RYTYDKLGKLQRRNEELEEQCVQHGRVhetmKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEV 698
Cdd:COG3206 323 EALQAREASLQAQLAQLEARLAELPEL----EAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNV 388
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
216-705 |
1.40e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 42.23 E-value: 1.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 216 AASAGEQLELEKLKLTYEEkceiEESQLKFLRNDLAEYQRTCEDLKEQLKHKEFLLAANTCNRVGglclkcAQHEAVLSQ 295
Cdd:COG1196 260 AELAELEAELEELRLELEE----LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE------LEEELAELE 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 296 THTNVHMQTIERLVKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERL 375
Cdd:COG1196 330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE 409
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 376 EKELASQQEKRAIEKDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCG 455
Cdd:COG1196 410 EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 456 EMRYQLNKtNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLR-----------IELDESKQHLEQEQQKAALAREECL-- 522
Cdd:COG1196 490 AARLLLLL-EAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaayeaaleAALAAALQNIVVEDDEVAAAAIEYLka 568
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 523 ----RLTELLGESEHQLHLTRQEKDSIQQSF----------SKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLL 588
Cdd:COG1196 569 akagRATFLPLDKIRARAALAAALARGAIGAavdlvasdlrEADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE 648
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 589 LTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDK 668
Cdd:COG1196 649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 28269672 669 HSQATAQQLVQLLSKQNQLLLE-----------RQSLSEEVDRLRTQL 705
Cdd:COG1196 729 QLEAEREELLEELLEEEELLEEealeelpeppdLEELERELERLEREI 776
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
467-705 |
1.52e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 41.88 E-value: 1.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 467 EKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQ 546
Cdd:pfam02463 171 KKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQ 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 547 QSFSKEAKAQALQAQQREQELTQKIQQMEAQHDK------------TENEQYLLLTSQNTFLTKLKEECCTLAKKLEQIS 614
Cdd:pfam02463 251 EEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQeeelkllakeeeELKSELLKLERRKVDDEEKLKESEKEKKKAEKEL 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 615 QKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSL 694
Cdd:pfam02463 331 KKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLL 410
|
250
....*....|.
gi 28269672 695 SEEVDRLRTQL 705
Cdd:pfam02463 411 LELARQLEDLL 421
|
|
| EmrA |
COG1566 |
Multidrug resistance efflux pump EmrA [Defense mechanisms]; |
313-464 |
1.57e-03 |
|
Multidrug resistance efflux pump EmrA [Defense mechanisms];
Pssm-ID: 441174 [Multi-domain] Cd Length: 331 Bit Score: 41.19 E-value: 1.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 313 DDLMSALVSVRSSLADTQQREASAYEQVKQVLQISE-EANFEKTKAliQCDQLRKELERQAERLEKELASQQEKRAIEkd 391
Cdd:COG1566 79 TDLQAALAQAEAQLAAAEAQLARLEAELGAEAEIAAaEAQLAAAQA--QLDLAQRELERYQALYKKGAVSQQELDEAR-- 154
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 28269672 392 mmkkeitkereymgSKMLILSQNIAQLEAQVEKvTKEKISAINQLEEIQSQLASREMDVTkvcgEMRYQLNKT 464
Cdd:COG1566 155 --------------AALDAAQAQLEAAQAQLAQ-AQAGLREEEELAAAQAQVAQAEAALA----QAELNLART 208
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
324-705 |
1.65e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 41.42 E-value: 1.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 324 SSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQQEKRAiEKDMMKKEITKEREY 403
Cdd:pfam07888 34 NRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHE-ELEEKYKELSASSEE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 404 MGSKMLILSQNIAQLEAQvekvtkekisaINQLEEIQSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEKEHREFRAKtn 483
Cdd:pfam07888 113 LSEEKDALLAQRAAHEAR-----------IRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAK-- 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 484 rdLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGES---EHQLHLTRQEKDSIQQSFSKEAKAQALQA 560
Cdd:pfam07888 180 --LQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAhrkEAENEALLEELRSLQERLNASERKVEGLG 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 561 QQREQELTQKIQ-QMEAQHDKTENEQYLLLTSQNTFltKLKEECCTLAKK---LEQISQKTRSEIAQLSQEKRYTYDKLG 636
Cdd:pfam07888 258 EELSSMAAQRDRtQAELHQARLQAAQLTLQLADASL--ALREGRARWAQEretLQQSAEADKDRIEKLSAELQRLEERLQ 335
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 28269672 637 KLQRRNEELEeqcVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQL 705
Cdd:pfam07888 336 EERMEREKLE---VELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRL 401
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
372-530 |
2.07e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.38 E-value: 2.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 372 AERLEKELASQQEKRAIEKDMMKKEITKEREymgskmlilsqNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVT 451
Cdd:COG2433 383 EELIEKELPEEEPEAEREKEHEERELTEEEE-----------EIRRLEEQVERLEAEVEELEAELEEKDERIERLERELS 451
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 28269672 452 KVcgemryqlnktnmeKDEAEKEHREfraktNRDLEIKDQEIEKLRIELDESKQHLEQEQQKaaLAREECLRLTELLGE 530
Cdd:COG2433 452 EA--------------RSEERREIRK-----DREISRLDREIERLERELEEERERIEELKRK--LERLKELWKLEHSGE 509
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
140-510 |
3.80e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 40.82 E-value: 3.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 140 KEELSGMKNKIQVVVLENEGLQQQLKSQRQEETLREQTLLDASGNmhnswittgedsgVGETSKRpfshDNADFGKAASA 219
Cdd:TIGR02169 673 PAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRK-------------IGEIEKE----IEQLEQEEEKL 735
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 220 GEQLELEKLKLTY-EEKCEIEESQLKFLRNDLAEYQRTCEDLKEQLkhkefllaantcnrvgglclkcAQHEAVLSQTHT 298
Cdd:TIGR02169 736 KERLEELEEDLSSlEQEIENVKSELKELEARIEELEEDLHKLEEAL----------------------NDLEARLSHSRI 793
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 299 NVHMQTIERLVKERDDLMSALVSVRSSLADTQQREASAYE--QVKQVLQISEEANFEKTKALIQCDQLRK-ELERQAERL 375
Cdd:TIGR02169 794 PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKeiQELQEQRIDLKEQIKSIEKEIENLNGKKeELEEELEEL 873
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 376 EKELASQQEKRaiekdmmkKEITKEREYMGSKMLILSQNIAQLEAQVEKvtkeKISAINQLEEIQSQLASREMDVTKVCG 455
Cdd:TIGR02169 874 EAALRDLESRL--------GDLKKERDELEAQLRELERKIEELEAQIEK----KRKRLSELKAKLEALEEELSEIEDPKG 941
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28269672 456 EMRYQ------LNKTNMEKDEAEKEHREFRAKTNRdlEIKDQEIEKLRI-ELDESKQHLEQE 510
Cdd:TIGR02169 942 EDEEIpeeelsLEDVQAELQRVEEEIRALEPVNML--AIQEYEEVLKRLdELKEKRAKLEEE 1001
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
340-551 |
7.96e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 39.66 E-value: 7.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 340 VKQVLQISEEANFEKTKAliqcdQLRKELERQAERLEKELASQQEkraIEKdmMKKEITKEREYMGSKMLILSQNIAQLE 419
Cdd:PRK03918 151 VRQILGLDDYENAYKNLG-----EVIKEIKRRIERLEKFIKRTEN---IEE--LIKEKEKELEEVLREINEISSELPELR 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 420 AQVEKVTKEKisaiNQLEEIQSQLASREMDVTKVCGEMR---YQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQ----- 491
Cdd:PRK03918 221 EELEKLEKEV----KELEELKEEIEELEKELESLEGSKRkleEKIRELEERIEELKKEIEELEEKVKELKELKEKaeeyi 296
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 28269672 492 EIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSK 551
Cdd:PRK03918 297 KLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEE 356
|
|
| |
