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Conserved domains on  [gi|194018748|ref|NP_006716|]
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T-cell differentiation antigen CD6 isoform 1 precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
161-260 2.64e-45

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


:

Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 156.35  E-value: 2.64e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194018748   161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDC 240
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80
                           90       100
                   ....*....|....*....|.
gi 194018748   241 PGLP-GQHYCGHKEDAGAVCS 260
Cdd:smart00202  81 PHSGwGSHNCSHGEDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
270-361 1.19e-26

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


:

Pssm-ID: 459844  Cd Length: 98  Bit Score: 104.00  E-value: 1.19e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194018748  270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKG---LPHSLSGRMYYS---CNGEELTLSNCSWR 343
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGcsyFGPGSTGPIWLDdvrCSGNETSLWQCPHR 80
                          90
                  ....*....|....*...
gi 194018748  344 FNNSNLCSQSLAARVLCS 361
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
50-156 2.65e-17

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


:

Pssm-ID: 459844  Cd Length: 98  Bit Score: 77.42  E-value: 2.65e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194018748   50 GSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQlappTPELPPPPAAGNTSVAanatlagapALLC 129
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPS----GCSYFGPGSTGPIWLD---------DVRC 67
                          90       100       110
                  ....*....|....*....|....*....|..
gi 194018748  130 SGAEWRLCE-----VVEHACrSDGRRARVTCA 156
Cdd:pfam00530  68 SGNETSLWQcphrpWGNHNC-SHSEDAGVICS 98
 
Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
161-260 2.64e-45

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 156.35  E-value: 2.64e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194018748   161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDC 240
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80
                           90       100
                   ....*....|....*....|.
gi 194018748   241 PGLP-GQHYCGHKEDAGAVCS 260
Cdd:smart00202  81 PHSGwGSHNCSHGEDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
166-260 9.28e-34

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 124.41  E-value: 9.28e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194018748  166 GGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLH--FTPGRGPIHRDQVNCSGAEAYLWDCP-G 242
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGCSyfGPGSTGPIWLDDVRCSGNETSLWQCPhR 80
                          90
                  ....*....|....*...
gi 194018748  243 LPGQHYCGHKEDAGAVCS 260
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
270-361 1.19e-26

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 104.00  E-value: 1.19e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194018748  270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKG---LPHSLSGRMYYS---CNGEELTLSNCSWR 343
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGcsyFGPGSTGPIWLDdvrCSGNETSLWQCPHR 80
                          90
                  ....*....|....*...
gi 194018748  344 FNNSNLCSQSLAARVLCS 361
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
265-361 1.71e-25

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 100.88  E-value: 1.71e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194018748   265 WRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKG-LPHSLSGRM---YYSCNGEELTLSNC 340
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSaYFGPGSGPIwldNVRCSGTEASLSDC 80
                           90       100
                   ....*....|....*....|.
gi 194018748   341 SWRFNNSNLCSQSLAARVLCS 361
Cdd:smart00202  81 PHSGWGSHNCSHGEDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
50-156 2.65e-17

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 77.42  E-value: 2.65e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194018748   50 GSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQlappTPELPPPPAAGNTSVAanatlagapALLC 129
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPS----GCSYFGPGSTGPIWLD---------DVRC 67
                          90       100       110
                  ....*....|....*....|....*....|..
gi 194018748  130 SGAEWRLCE-----VVEHACrSDGRRARVTCA 156
Cdd:pfam00530  68 SGNETSLWQcphrpWGNHNC-SHSEDAGVICS 98
 
Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
161-260 2.64e-45

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 156.35  E-value: 2.64e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194018748   161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDC 240
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80
                           90       100
                   ....*....|....*....|.
gi 194018748   241 PGLP-GQHYCGHKEDAGAVCS 260
Cdd:smart00202  81 PHSGwGSHNCSHGEDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
166-260 9.28e-34

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 124.41  E-value: 9.28e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194018748  166 GGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLH--FTPGRGPIHRDQVNCSGAEAYLWDCP-G 242
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGCSyfGPGSTGPIWLDDVRCSGNETSLWQCPhR 80
                          90
                  ....*....|....*...
gi 194018748  243 LPGQHYCGHKEDAGAVCS 260
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
270-361 1.19e-26

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 104.00  E-value: 1.19e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194018748  270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKG---LPHSLSGRMYYS---CNGEELTLSNCSWR 343
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGcsyFGPGSTGPIWLDdvrCSGNETSLWQCPHR 80
                          90
                  ....*....|....*...
gi 194018748  344 FNNSNLCSQSLAARVLCS 361
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
265-361 1.71e-25

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 100.88  E-value: 1.71e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194018748   265 WRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKG-LPHSLSGRM---YYSCNGEELTLSNC 340
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSaYFGPGSGPIwldNVRCSGTEASLSDC 80
                           90       100
                   ....*....|....*....|.
gi 194018748   341 SWRFNNSNLCSQSLAARVLCS 361
Cdd:smart00202  81 PHSGWGSHNCSHGEDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
50-156 2.65e-17

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 77.42  E-value: 2.65e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194018748   50 GSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQlappTPELPPPPAAGNTSVAanatlagapALLC 129
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPS----GCSYFGPGSTGPIWLD---------DVRC 67
                          90       100       110
                  ....*....|....*....|....*....|..
gi 194018748  130 SGAEWRLCE-----VVEHACrSDGRRARVTCA 156
Cdd:pfam00530  68 SGNETSLWQcphrpWGNHNC-SHSEDAGVICS 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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