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Conserved domains on  [gi|6005701|ref|NP_009099|]
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ABC-type organic anion transporter ABCA8 isoform 2 [Homo sapiens]

Protein Classification

ABC transporter A family member( domain architecture ID 13259938)

ABC transporter A family member (ABCA) may mediate the transport of a variety of lipid compounds; contains the ATP-binding and transmembrane (TM) components of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
1245-1466 7.31e-85

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


:

Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 276.69  E-value: 7.31e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1245 LRKEYagkrkgcfsKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEF 1320
Cdd:cd03263    6 LTKTY---------KKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGysirTDRKAARQS 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1321 LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVL 1400
Cdd:cd03263   77 LGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLL 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701  1401 LDEPSTGMDPEGQQQMWQAIRATFRNteRGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLK 1466
Cdd:cd03263  157 LDEPTSGLDPASRRAIWDLILEVRKG--RSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
rim_protein super family cl31083
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
235-750 2.07e-64

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


The actual alignment was detected with superfamily member TIGR01257:

Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 243.00  E-value: 2.07e-64
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     235 SFIYYASVNVT----RERKRMKALMTMMGLRDSAFWLSWgLLYAGFIFIMALFL-ALVIRSTQFIILSGFMVVFSLFLLY 309
Cdd:TIGR01257  662 AWIYSVSMTVKsivlEKELRLKETLKNQGVSNAVIWCTW-FLDSFSIMSMSIFLlTIFIMHGRILHYSDPFILFLFLLAF 740
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     310 GLSLVALAFLMSILVKKSFL----TGLVVFLLTV-FWGCLGFTSlyrHLPASLEWILSLLSPFAFMLGMAQLLHLDYD-- 382
Cdd:TIGR01257  741 STATIMQCFLLSTFFSKASLaaacSGVIYFTLYLpHILCFAWQD---RMTADLKTAVSLLSPVAFGFGTEYLVRFEEQgl 817
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     383 ----LNSNAFPHPSDGSNLIVATNFMLaFDTCLYLALAIYFEKILPNEYGHRRPPLFFLKSSFW-----------SQTQK 447
Cdd:TIGR01257  818 glqwSNIGNSPLEGDEFSFLLSMKMML-LDAALYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWlggegcstreeRALEK 896
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     448 TDHVALEDEMDADPS-FHDSF-EQAPPEFQgkEAIRIRNVTK--EYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKS 523
Cdd:TIGR01257  897 TEPLTEEMEDPEHPEgINDSFfERELPGLV--PGVCVKNLVKifEPSGRP----AVDRLNITFYENQITAFLGHNGAGKT 970
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     524 TLLNILSGLSVPTKGSVTIYNNKLSemADLENLSKLTGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEV---------- 593
Cdd:TIGR01257  971 TTLSILTGLLPPTSGTVLVGGKDIE--TNLDAVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGRSWEEAqlemeamled 1048
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     594 ------------------------------DKEIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADILAD 643
Cdd:TIGR01257 1049 tglhhkrneeaqdlsggmqrklsvaiafvgDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD 1128
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     644 RKVFLSQGKLKCAGSSLFLKKKWGIGYHLSL--QLNEI------------------------CVEE------------NI 685
Cdd:TIGR01257 1129 RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLvrKMKNIqsqrggcegtcsctskgfstrcpaRVDEitpeqvldgdvnEL 1208
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701     686 TSLVKQHIPDAKLSAKSEGKLIYTLPLE--RTNKFPELYKDL-DSYPDLGIENYGVSMTTLNEVFLKL 750
Cdd:TIGR01257 1209 MDLVYHHVPEAKLVECIGQELIFLLPNKnfKQRAYASLFRELeETLADLGLSSFGISDTPLEEIFLKV 1276
rim_protein super family cl31083
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
993-1558 3.17e-60

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


The actual alignment was detected with superfamily member TIGR01257:

Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 229.51  E-value: 3.17e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     993 SSCPPYIAMSSIDDYKNRARSQLRISGLSPSAYWFGQALVDVSLY-----FLVFVFIYLMSYISNFEDMLLTIIHIIQIp 1067
Cdd:TIGR01257 1691 SFVPASFVLYLIQERVNKAKHLQFISGVSPTTYWLTNFLWDIMNYavsagLVVGIFIGFQKKAYTSPENLPALVALLML- 1769
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1068 cavgYSFSLIFMTYVISFIFRKGRKNSGIWSFCFYVVTVFSVA-GFAFSIFESD------------IPFIFTFLIPPATM 1134
Cdd:TIGR01257 1770 ----YGWAVIPMMYPASFLFDVPSTAYVALSCANLFIGINSSAiTFVLELFENNrtllrfnamlrkLLIVFPHFCLGRGL 1845
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1135 IGCLFLSSHLLFSSLFSEERmDVQPFL-------VFLIPFLHFIIFLFTLRCLEWKFGKKSMRKDPFFRISPRSSDVCQn 1207
Cdd:TIGR01257 1846 IDLALSQAVTDVYAQFGEEH-SANPFQwdligknLVAMAVEGVVYFLLTLLIQHHFFLSRWIAEPAKEPIFDEDDDVAE- 1923
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1208 peepegededvqmERVRTANALNSTNfdekpVIIASCLRKEYAGKrkgcfskrkNKIATRNVSFCVRKGEVLGLLGHNGA 1287
Cdd:TIGR01257 1924 -------------ERQRIISGGNKTD-----ILRLNELTKVYSGT---------SSPAVDRLCVGVRPGECFGLLGVNGA 1976
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1288 GKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFLGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVD 1363
Cdd:TIGR01257 1977 GKTTTFKMLTGDTTVTSGDATVAGksilTNISDVHQNMGYCPQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQ 2056
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1364 ALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNtERGALLTTHYMAEAEA 1443
Cdd:TIGR01257 2057 SLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIRE-GRAVVLTSHSMEECEA 2135
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1444 VCDRVAIMVSGRLRCIGSIQHLKSKFGKDYLLEMKVKN-----LAQVEPLHAEILRLFPQAARQERYSSLMVYKLPVEDv 1518
Cdd:TIGR01257 2136 LCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIKSpkddlLPDLNPVEQFFQGNFPGSVQRERHYNMLQFQVSSSS- 2214
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 6005701    1519 qpLAQAFFKLEKVKQSFDLEEYSLSQSTLEQVFLELSKEQ 1558
Cdd:TIGR01257 2215 --LARIFQLLISHKDSLLIEEYSVTQTTLDQVFVNFAKQQ 2252
 
Name Accession Description Interval E-value
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
1245-1466 7.31e-85

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 276.69  E-value: 7.31e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1245 LRKEYagkrkgcfsKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEF 1320
Cdd:cd03263    6 LTKTY---------KKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGysirTDRKAARQS 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1321 LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVL 1400
Cdd:cd03263   77 LGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLL 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701  1401 LDEPSTGMDPEGQQQMWQAIRATFRNteRGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLK 1466
Cdd:cd03263  157 LDEPTSGLDPASRRAIWDLILEVRKG--RSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
1258-1469 2.37e-73

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 244.59  E-value: 2.37e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1258 SKR-KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFLGYCPQENALWP 1332
Cdd:COG1131    7 TKRyGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGedvaRDPAEVRRRIGYVPQEPALYP 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1333 NLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEG 1412
Cdd:COG1131   87 DLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPTSGLDPEA 166
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701  1413 QQQMWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKF 1469
Cdd:COG1131  167 RRELWELLRE-LAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARL 222
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
235-750 2.07e-64

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 243.00  E-value: 2.07e-64
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     235 SFIYYASVNVT----RERKRMKALMTMMGLRDSAFWLSWgLLYAGFIFIMALFL-ALVIRSTQFIILSGFMVVFSLFLLY 309
Cdd:TIGR01257  662 AWIYSVSMTVKsivlEKELRLKETLKNQGVSNAVIWCTW-FLDSFSIMSMSIFLlTIFIMHGRILHYSDPFILFLFLLAF 740
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     310 GLSLVALAFLMSILVKKSFL----TGLVVFLLTV-FWGCLGFTSlyrHLPASLEWILSLLSPFAFMLGMAQLLHLDYD-- 382
Cdd:TIGR01257  741 STATIMQCFLLSTFFSKASLaaacSGVIYFTLYLpHILCFAWQD---RMTADLKTAVSLLSPVAFGFGTEYLVRFEEQgl 817
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     383 ----LNSNAFPHPSDGSNLIVATNFMLaFDTCLYLALAIYFEKILPNEYGHRRPPLFFLKSSFW-----------SQTQK 447
Cdd:TIGR01257  818 glqwSNIGNSPLEGDEFSFLLSMKMML-LDAALYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWlggegcstreeRALEK 896
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     448 TDHVALEDEMDADPS-FHDSF-EQAPPEFQgkEAIRIRNVTK--EYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKS 523
Cdd:TIGR01257  897 TEPLTEEMEDPEHPEgINDSFfERELPGLV--PGVCVKNLVKifEPSGRP----AVDRLNITFYENQITAFLGHNGAGKT 970
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     524 TLLNILSGLSVPTKGSVTIYNNKLSemADLENLSKLTGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEV---------- 593
Cdd:TIGR01257  971 TTLSILTGLLPPTSGTVLVGGKDIE--TNLDAVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGRSWEEAqlemeamled 1048
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     594 ------------------------------DKEIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADILAD 643
Cdd:TIGR01257 1049 tglhhkrneeaqdlsggmqrklsvaiafvgDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD 1128
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     644 RKVFLSQGKLKCAGSSLFLKKKWGIGYHLSL--QLNEI------------------------CVEE------------NI 685
Cdd:TIGR01257 1129 RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLvrKMKNIqsqrggcegtcsctskgfstrcpaRVDEitpeqvldgdvnEL 1208
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701     686 TSLVKQHIPDAKLSAKSEGKLIYTLPLE--RTNKFPELYKDL-DSYPDLGIENYGVSMTTLNEVFLKL 750
Cdd:TIGR01257 1209 MDLVYHHVPEAKLVECIGQELIFLLPNKnfKQRAYASLFRELeETLADLGLSSFGISDTPLEEIFLKV 1276
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
480-663 7.46e-63

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 213.52  E-value: 7.46e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPDKieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIynNKLSEMADLENLSKL 559
Cdd:cd03263    1 LQIRNLTKTYKKGTKP--AVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYI--NGYSIRTDRKAARQS 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDKE----------------------------------------IFL 599
Cdd:cd03263   77 LGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEvelllrvlgltdkankrartlsggmkrklslaialiggpsVLL 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701   600 LDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGSSLFLK 663
Cdd:cd03263  157 LDEPTSGLDPASRRAIWDLILEVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
993-1558 3.17e-60

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 229.51  E-value: 3.17e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     993 SSCPPYIAMSSIDDYKNRARSQLRISGLSPSAYWFGQALVDVSLY-----FLVFVFIYLMSYISNFEDMLLTIIHIIQIp 1067
Cdd:TIGR01257 1691 SFVPASFVLYLIQERVNKAKHLQFISGVSPTTYWLTNFLWDIMNYavsagLVVGIFIGFQKKAYTSPENLPALVALLML- 1769
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1068 cavgYSFSLIFMTYVISFIFRKGRKNSGIWSFCFYVVTVFSVA-GFAFSIFESD------------IPFIFTFLIPPATM 1134
Cdd:TIGR01257 1770 ----YGWAVIPMMYPASFLFDVPSTAYVALSCANLFIGINSSAiTFVLELFENNrtllrfnamlrkLLIVFPHFCLGRGL 1845
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1135 IGCLFLSSHLLFSSLFSEERmDVQPFL-------VFLIPFLHFIIFLFTLRCLEWKFGKKSMRKDPFFRISPRSSDVCQn 1207
Cdd:TIGR01257 1846 IDLALSQAVTDVYAQFGEEH-SANPFQwdligknLVAMAVEGVVYFLLTLLIQHHFFLSRWIAEPAKEPIFDEDDDVAE- 1923
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1208 peepegededvqmERVRTANALNSTNfdekpVIIASCLRKEYAGKrkgcfskrkNKIATRNVSFCVRKGEVLGLLGHNGA 1287
Cdd:TIGR01257 1924 -------------ERQRIISGGNKTD-----ILRLNELTKVYSGT---------SSPAVDRLCVGVRPGECFGLLGVNGA 1976
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1288 GKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFLGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVD 1363
Cdd:TIGR01257 1977 GKTTTFKMLTGDTTVTSGDATVAGksilTNISDVHQNMGYCPQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQ 2056
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1364 ALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNtERGALLTTHYMAEAEA 1443
Cdd:TIGR01257 2057 SLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIRE-GRAVVLTSHSMEECEA 2135
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1444 VCDRVAIMVSGRLRCIGSIQHLKSKFGKDYLLEMKVKN-----LAQVEPLHAEILRLFPQAARQERYSSLMVYKLPVEDv 1518
Cdd:TIGR01257 2136 LCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIKSpkddlLPDLNPVEQFFQGNFPGSVQRERHYNMLQFQVSSSS- 2214
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 6005701    1519 qpLAQAFFKLEKVKQSFDLEEYSLSQSTLEQVFLELSKEQ 1558
Cdd:TIGR01257 2215 --LARIFQLLISHKDSLLIEEYSVTQTTLDQVFVNFAKQQ 2252
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
1259-1554 6.59e-54

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 191.06  E-value: 6.59e-54
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1259 KRKNKI-ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFLGYCPQENALWPN 1333
Cdd:TIGR01188    1 KVYGDFkAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGydvvREPRKVRRSIGIVPQYASVDED 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1334 LTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQ 1413
Cdd:TIGR01188   81 LTGRENLEMMGRLYGLPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTR 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1414 QQMWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFGKDYlLEMKVKNLAQVEPLHAEIL 1493
Cdd:TIGR01188  161 RAIWDYIRA-LKEEGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRRLGKDT-LESRPRDIQSLKVEVSMLI 238
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6005701    1494 RLFP--QAARQERYSSLMVYKLPVEDVQPLAQAFFKlEKVKQSFDLEEYSLSQSTLEQVFLEL 1554
Cdd:TIGR01188  239 AELGetGLGLLAVTVDSDRIKILVPDGDETVPEIVE-AAIRNGIRIRSISTERPSLDDVFLKL 300
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
480-658 2.65e-50

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 178.33  E-value: 2.65e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEmaDLENLSKL 559
Cdd:COG1131    1 IEVRGLTKRYGDKT----ALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVAR--DPAEVRRR 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDK----------------------------------------EIFL 599
Cdd:COG1131   75 IGYVPQEPALYPDLTVRENLRFFARLYGLPRKEAREridellelfgltdaadrkvgtlsggmkqrlglalallhdpELLI 154
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   600 LDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:COG1131  155 LDEPTSGLDPEARRELWELLRElAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGT 214
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
1263-1555 1.35e-40

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 152.65  E-value: 1.35e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1263 KIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFLGYCPQENALWPNLTVRQ 1338
Cdd:PRK13537   20 KLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGepvpSRARHARQRVGVVPQFDNLDPDFTVRE 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1339 HLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQ 1418
Cdd:PRK13537  100 NLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDPQARHLMWE 179
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1419 AIRATFrntERGA--LLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHL-KSKFGKDyLLEMKVKNLAQVEPLhaeilrL 1495
Cdd:PRK13537  180 RLRSLL---ARGKtiLLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALiESEIGCD-VIEIYGPDPVALRDE------L 249
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   1496 FPQAARQE-RYSSLMVYklpVEDVQPLAQAffklekVKQSFDLeEYSLSQSTLEQVFLELS 1555
Cdd:PRK13537  250 APLAERTEiSGETLFCY---VRDPEPLHAR------LKGRAGL-RYLHRPANLEDVFLRLT 300
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
1267-1406 1.46e-34

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 129.69  E-value: 1.46e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-SGGGDALEFL----GYCPQENALWPNLTVRQHLE 1341
Cdd:pfam00005    2 KNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGqDLTDDERKSLrkeiGYVFQDPQLFPRLTVRENLR 81
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701    1342 VYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPV----KTLSEGIKRKLCFVLSILGNPSVVLLDEPST 1406
Cdd:pfam00005   82 LGLLLKGLSKREKDARAEEALEKLGLGDLADRPVgerpGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
1235-1474 6.21e-25

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 112.91  E-value: 6.21e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1235 DEKPVIIASCLRKeyagkRKGCFskrknkIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG--- 1311
Cdd:NF033858  262 DDEPAIEARGLTM-----RFGDF------TAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGqpv 330
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1312 -SGGGDALEFLGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVL 1390
Cdd:NF033858  331 dAGDIATRRRVGYMSQAFSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAV 410
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1391 SILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAvCDRVAIMVSGRLRCIGSIQHLKSKFG 1470
Cdd:NF033858  411 AVIHKPELLILDEPTSGVDPVARDMFWRLLIELSREDGVTIFISTHFMNEAER-CDRISLMHAGRVLASDTPAALVAARG 489

                  ....
gi 6005701   1471 KDYL 1474
Cdd:NF033858  490 AATL 493
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
499-597 3.70e-24

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 100.03  E-value: 3.70e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     499 LKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIyNNKLSEMADLENLSKLTGVCPQSNVQFDFLTVREN 578
Cdd:pfam00005    1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILL-DGQDLTDDERKSLRKEIGYVFQDPQLFPRLTVREN 79
                           90
                   ....*....|....*....
gi 6005701     579 LRLFAKIKGILPQEVDKEI 597
Cdd:pfam00005   80 LRLGLLLKGLSKREKDARA 98
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
479-691 1.34e-23

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 102.38  E-value: 1.34e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYKgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEmADLENLSK 558
Cdd:PRK13632    7 MIKVENVSFSYP--NSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISK-ENLKEIRK 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    559 LTGVCPQS-NVQFDFLTVR-------ENLRL-FAKIKGIL----------------PQE----------------VDKEI 597
Cdd:PRK13632   84 KIGIIFQNpDNQFIGATVEddiafglENKKVpPKKMKDIIddlakkvgmedyldkePQNlsggqkqrvaiasvlaLNPEI 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    598 FLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEAdILADRKVFLSQGKLKCAGS-SLFLKKKWGIG----- 669
Cdd:PRK13632  164 IIFDESTSMLDPKGKREIKKIMVDlrKTRKKTLISITHDMDEA-ILADKVIVFSEGKLIAQGKpKEILNNKEILEkakid 242
                         250       260
                  ....*....|....*....|....*.
gi 6005701    670 ----YHLSLQLNEICVEENITSLVKQ 691
Cdd:PRK13632  243 spfiYKLSKKLKGIDPTYNEEELIEQ 268
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
1265-1490 9.44e-19

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 89.79  E-value: 9.44e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSiKVITGDTKPTAGQvllkgsgggDALEFLGYCPQENALW------------- 1331
Cdd:NF000106   28 AVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGR---------RPWRF*TWCANRRALRrtig*hrpvr*gr 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1332 -PNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDP 1410
Cdd:NF000106   98 rESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDP 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1411 EGQQQMWQAIRATFRNTERgALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFGKDYLlemkvknlaQVEPLHA 1490
Cdd:NF000106  178 RTRNEVWDEVRSMVRDGAT-VLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVGGRTL---------QIRPAHA 247
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
1265-1474 1.42e-15

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 82.48  E-value: 1.42e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQ--VLlkgsgGGD--------------AleflgYCPQ-- 1326
Cdd:NF033858   16 ALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRveVL-----GGDmadarhrravcpriA-----YMPQgl 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1327 -ENaLWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRK--LCFVLsiLGNPSVVLLDE 1403
Cdd:NF033858   86 gKN-LYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKlgLCCAL--IHDPDLLILDE 162
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701   1404 PSTGMDPEGQQQMWQ---AIRAtfrntERGA---LLTTHYMAEAEAvCDRVAIMVSGRLRCIGSIQHLKSKFGKDYL 1474
Cdd:NF033858  163 PTTGVDPLSRRQFWElidRIRA-----ERPGmsvLVATAYMEEAER-FDWLVAMDAGRVLATGTPAELLARTGADTL 233
ABC2_membrane_3 pfam12698
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter ...
883-1128 2.19e-13

ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter family pfam01061.


Pssm-ID: 463674 [Multi-domain]  Cd Length: 345  Bit Score: 73.58  E-value: 2.19e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     883 ASIDDFIQSVEHQNI--ALEVDAFGTRNGTDDPSYNgaITVCCNEKNYSFSLACNAKRLNCFPVLMDIVSNGLLGMVKPS 960
Cdd:pfam12698   65 DSEEEAKEALKNGKIdgLLVIPKGFSKDLLKGESAT--VTVYINSSNLLVSKLILNALQSLLQQLNASALVLLLEALSTS 142
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     961 VHIRTErSTFLENGQDNPIGFLAYIMFWLVLTSSCPpYIAMSSIDDYKNRARSQLRISGLSPSAYWFGQALVDVSLYFLV 1040
Cdd:pfam12698  143 APIPVE-STPLFNPQSGYAYYLVGLILMIIILIGAA-IIAVSIVEEKESRIKERLLVSGVSPLQYWLGKILGDFLVGLLQ 220
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1041 FVFIYLMSYISNFEDMLLTIIHIIQIPcavgYSFSLIFMTYVISFIFRKGRKNSGIWSFCFYVVTVFSVAGFAFSIFESD 1120
Cdd:pfam12698  221 LLIILLLLFGIGIPFGNLGLLLLLFLL----YGLAYIALGYLLGSLFKNSEDAQSIIGIVILLLSGFFGGLFPLEDPPSF 296

                   ....*...
gi 6005701    1121 IPFIFTFL 1128
Cdd:pfam12698  297 LQWIFSII 304
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
479-639 7.75e-13

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 73.62  E-value: 7.75e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYKgkpdKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNnklsemADLENLSK 558
Cdd:NF033858    1 VARLEGVSHRYG----KTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLG------GDMADARH 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    559 LTGVCPQ---------SNVQFDfLTVRENL----RLF--------AKIK------GILP--------------QEV---- 593
Cdd:NF033858   71 RRAVCPRiaympqglgKNLYPT-LSVFENLdffgRLFgqdaaerrRRIDellratGLAPfadrpagklsggmkQKLglcc 149
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 6005701    594 ----DKEIFLLDEPTAGLDPFSRHQVWNLLKERKTDRV---ILFSTQFMDEAD 639
Cdd:NF033858  150 alihDPDLLILDEPTTGVDPLSRRQFWELIDRIRAERPgmsVLVATAYMEEAE 202
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
504-638 9.52e-11

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 66.69  E-value: 9.52e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    504 FDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLsemaDLENLS--KLTGVCPQSnvqfdF-----LTVR 576
Cdd:NF033858  287 FRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPV----DAGDIAtrRRVGYMSQA-----FslygeLTVR 357
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    577 ENLRLFAKIKGILPQEVDK----------------------------------------EIFLLDEPTAGLDPFSRHQVW 616
Cdd:NF033858  358 QNLELHARLFHLPAAEIAArvaemlerfdladvadalpdslplgirqrlslavavihkpELLILDEPTSGVDPVARDMFW 437
                         170       180
                  ....*....|....*....|....*
gi 6005701    617 NLLKE--RKtDRVILF-STQFMDEA 638
Cdd:NF033858  438 RLLIElsRE-DGVTIFiSTHFMNEA 461
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
489-648 4.21e-10

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 60.71  E-value: 4.21e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    489 YKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI-------YNNKLSEMAD--------- 552
Cdd:NF040873    2 YGGRP----VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRaggarvaYVPQRSEVPDslpltvrdl 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    553 --------LENLSKLT--------------GVCPQSNVQFDFLTVRENLR-LFAKIkgiLPQEVDkeIFLLDEPTAGLDP 609
Cdd:NF040873   78 vamgrwarRGLWRRLTrddraavddalervGLADLAGRQLGELSGGQRQRaLLAQG---LAQEAD--LLLLDEPTTGLDA 152
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 6005701    610 FSRHQVWNLLKE-RKTDRVILFSTQFMDEAdILADRKVFL 648
Cdd:NF040873  153 ESRERIIALLAEeHARGATVVVVTHDLELV-RRADPCVLL 191
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
509-651 2.12e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 51.99  E-value: 2.12e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701      509 GQITAILGHSGAGKSTLLNILSGLSVPTKGSVtIYNNKLSEMADLENLSKLTGVCPQSNVQFDFLTVRenlRLFAKIKgi 588
Cdd:smart00382    2 GEVILIVGPPGSGKTTLARALARELGPPGGGV-IYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLR---LALALAR-- 75
                            90       100       110       120       130       140       150
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701      589 lpqEVDKEIFLLDEPTAGLDPFSRHQVWNLL-------KERKTDRVILFSTQFMDEAD-----ILADRKVFLSQG 651
Cdd:smart00382   76 ---KLKPDVLILDEITSLLDAEQEALLLLLEelrllllLKSEKNLTVILTTNDEKDLGpallrRRFDRRIVLLLI 147
GguA NF040905
sugar ABC transporter ATP-binding protein;
481-531 4.62e-07

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 54.41  E-value: 4.62e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 6005701    481 RIRNVTKEYKGkpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSG 531
Cdd:NF040905    3 EMRGITKTFPG----VKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSG 49
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
597-667 4.79e-07

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 53.97  E-value: 4.79e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701    597 IFLLDEPTAGLDPFSRHQVWNLLKERKTD-RVILFSTQFMDEADILADRKVFLSQGKLKCAGSSLFLKKKWG 667
Cdd:NF000106  165 VLYLDEPTTGLDPRTRNEVWDEVRSMVRDgATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVG 236
GguA NF040905
sugar ABC transporter ATP-binding protein;
1265-1298 4.89e-05

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 47.86  E-value: 4.89e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITG 1298
Cdd:NF040905   16 ALDDVNLSVREGEIHALCGENGAGKSTLMKVLSG 49
 
Name Accession Description Interval E-value
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
1245-1466 7.31e-85

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 276.69  E-value: 7.31e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1245 LRKEYagkrkgcfsKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEF 1320
Cdd:cd03263    6 LTKTY---------KKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGysirTDRKAARQS 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1321 LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVL 1400
Cdd:cd03263   77 LGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLL 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701  1401 LDEPSTGMDPEGQQQMWQAIRATFRNteRGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLK 1466
Cdd:cd03263  157 LDEPTSGLDPASRRAIWDLILEVRKG--RSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
1258-1469 2.37e-73

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 244.59  E-value: 2.37e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1258 SKR-KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFLGYCPQENALWP 1332
Cdd:COG1131    7 TKRyGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGedvaRDPAEVRRRIGYVPQEPALYP 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1333 NLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEG 1412
Cdd:COG1131   87 DLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPTSGLDPEA 166
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701  1413 QQQMWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKF 1469
Cdd:COG1131  167 RRELWELLRE-LAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARL 222
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
235-750 2.07e-64

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 243.00  E-value: 2.07e-64
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     235 SFIYYASVNVT----RERKRMKALMTMMGLRDSAFWLSWgLLYAGFIFIMALFL-ALVIRSTQFIILSGFMVVFSLFLLY 309
Cdd:TIGR01257  662 AWIYSVSMTVKsivlEKELRLKETLKNQGVSNAVIWCTW-FLDSFSIMSMSIFLlTIFIMHGRILHYSDPFILFLFLLAF 740
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     310 GLSLVALAFLMSILVKKSFL----TGLVVFLLTV-FWGCLGFTSlyrHLPASLEWILSLLSPFAFMLGMAQLLHLDYD-- 382
Cdd:TIGR01257  741 STATIMQCFLLSTFFSKASLaaacSGVIYFTLYLpHILCFAWQD---RMTADLKTAVSLLSPVAFGFGTEYLVRFEEQgl 817
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     383 ----LNSNAFPHPSDGSNLIVATNFMLaFDTCLYLALAIYFEKILPNEYGHRRPPLFFLKSSFW-----------SQTQK 447
Cdd:TIGR01257  818 glqwSNIGNSPLEGDEFSFLLSMKMML-LDAALYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWlggegcstreeRALEK 896
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     448 TDHVALEDEMDADPS-FHDSF-EQAPPEFQgkEAIRIRNVTK--EYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKS 523
Cdd:TIGR01257  897 TEPLTEEMEDPEHPEgINDSFfERELPGLV--PGVCVKNLVKifEPSGRP----AVDRLNITFYENQITAFLGHNGAGKT 970
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     524 TLLNILSGLSVPTKGSVTIYNNKLSemADLENLSKLTGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEV---------- 593
Cdd:TIGR01257  971 TTLSILTGLLPPTSGTVLVGGKDIE--TNLDAVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGRSWEEAqlemeamled 1048
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     594 ------------------------------DKEIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADILAD 643
Cdd:TIGR01257 1049 tglhhkrneeaqdlsggmqrklsvaiafvgDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD 1128
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     644 RKVFLSQGKLKCAGSSLFLKKKWGIGYHLSL--QLNEI------------------------CVEE------------NI 685
Cdd:TIGR01257 1129 RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLvrKMKNIqsqrggcegtcsctskgfstrcpaRVDEitpeqvldgdvnEL 1208
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701     686 TSLVKQHIPDAKLSAKSEGKLIYTLPLE--RTNKFPELYKDL-DSYPDLGIENYGVSMTTLNEVFLKL 750
Cdd:TIGR01257 1209 MDLVYHHVPEAKLVECIGQELIFLLPNKnfKQRAYASLFRELeETLADLGLSSFGISDTPLEEIFLKV 1276
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
480-663 7.46e-63

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 213.52  E-value: 7.46e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPDKieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIynNKLSEMADLENLSKL 559
Cdd:cd03263    1 LQIRNLTKTYKKGTKP--AVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYI--NGYSIRTDRKAARQS 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDKE----------------------------------------IFL 599
Cdd:cd03263   77 LGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEvelllrvlgltdkankrartlsggmkrklslaialiggpsVLL 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701   600 LDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGSSLFLK 663
Cdd:cd03263  157 LDEPTSGLDPASRRAIWDLILEVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
993-1558 3.17e-60

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 229.51  E-value: 3.17e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     993 SSCPPYIAMSSIDDYKNRARSQLRISGLSPSAYWFGQALVDVSLY-----FLVFVFIYLMSYISNFEDMLLTIIHIIQIp 1067
Cdd:TIGR01257 1691 SFVPASFVLYLIQERVNKAKHLQFISGVSPTTYWLTNFLWDIMNYavsagLVVGIFIGFQKKAYTSPENLPALVALLML- 1769
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1068 cavgYSFSLIFMTYVISFIFRKGRKNSGIWSFCFYVVTVFSVA-GFAFSIFESD------------IPFIFTFLIPPATM 1134
Cdd:TIGR01257 1770 ----YGWAVIPMMYPASFLFDVPSTAYVALSCANLFIGINSSAiTFVLELFENNrtllrfnamlrkLLIVFPHFCLGRGL 1845
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1135 IGCLFLSSHLLFSSLFSEERmDVQPFL-------VFLIPFLHFIIFLFTLRCLEWKFGKKSMRKDPFFRISPRSSDVCQn 1207
Cdd:TIGR01257 1846 IDLALSQAVTDVYAQFGEEH-SANPFQwdligknLVAMAVEGVVYFLLTLLIQHHFFLSRWIAEPAKEPIFDEDDDVAE- 1923
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1208 peepegededvqmERVRTANALNSTNfdekpVIIASCLRKEYAGKrkgcfskrkNKIATRNVSFCVRKGEVLGLLGHNGA 1287
Cdd:TIGR01257 1924 -------------ERQRIISGGNKTD-----ILRLNELTKVYSGT---------SSPAVDRLCVGVRPGECFGLLGVNGA 1976
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1288 GKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFLGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVD 1363
Cdd:TIGR01257 1977 GKTTTFKMLTGDTTVTSGDATVAGksilTNISDVHQNMGYCPQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQ 2056
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1364 ALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNtERGALLTTHYMAEAEA 1443
Cdd:TIGR01257 2057 SLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIRE-GRAVVLTSHSMEECEA 2135
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1444 VCDRVAIMVSGRLRCIGSIQHLKSKFGKDYLLEMKVKN-----LAQVEPLHAEILRLFPQAARQERYSSLMVYKLPVEDv 1518
Cdd:TIGR01257 2136 LCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIKSpkddlLPDLNPVEQFFQGNFPGSVQRERHYNMLQFQVSSSS- 2214
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 6005701    1519 qpLAQAFFKLEKVKQSFDLEEYSLSQSTLEQVFLELSKEQ 1558
Cdd:TIGR01257 2215 --LARIFQLLISHKDSLLIEEYSVTQTTLDQVFVNFAKQQ 2252
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
1261-1489 3.36e-56

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 195.46  E-value: 3.36e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1261 KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGD----ALEFLGYCPQENALWPNLTV 1336
Cdd:COG4555   12 GKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKepreARRQIGVLPDERGLYDRLTV 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1337 RQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQM 1416
Cdd:COG4555   92 RENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTNGLDVMARRLL 171
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6005701  1417 WQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFGKDYLLEMKVKNLAQVEPLH 1489
Cdd:COG4555  172 REILRA-LKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGEENLEDAFVALIGSEEGEA 243
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
1258-1456 1.45e-55

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 190.69  E-value: 1.45e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1258 SKR-KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFLGYCPQENALWP 1332
Cdd:cd03230    7 SKRyGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGkdikKEPEEVKRRIGYLPEEPSLYE 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1333 NLTVRQHLEvyaavkglrkgdaevaitrlvdalklqdqlkspvktLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEG 1412
Cdd:cd03230   87 NLTVRENLK------------------------------------LSGGMKQRLALAQALLHDPELLILDEPTSGLDPES 130
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 6005701  1413 QQQMWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:cd03230  131 RREFWELLR-ELKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
1258-1559 5.67e-55

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 194.17  E-value: 5.67e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1258 SKR-KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSG-GGDALEFLGYCPQENALWPNLT 1335
Cdd:COG4152    8 TKRfGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPlDPEDRRRIGYLPEERGLYPKMK 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1336 VRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQ 1415
Cdd:COG4152   88 VGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPFSGLDPVNVEL 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1416 MWQAIRAtFRntERGA--LLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFGkdyllemkvKNLAQVEPLH-AEI 1492
Cdd:COG4152  168 LKDVIRE-LA--AKGTtvIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFG---------RNTLRLEADGdAGW 235
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701  1493 LRLFPQAARQERYSSLMVYKLP-VEDVQPLaqaffkLEKVKQSFDLEEYSLSQSTLEQVFLELSKEQE 1559
Cdd:COG4152  236 LRALPGVTVVEEDGDGAELKLEdGADAQEL------LRALLARGPVREFEEVRPSLNEIFIEVVGEKA 297
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
1259-1554 6.59e-54

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 191.06  E-value: 6.59e-54
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1259 KRKNKI-ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFLGYCPQENALWPN 1333
Cdd:TIGR01188    1 KVYGDFkAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGydvvREPRKVRRSIGIVPQYASVDED 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1334 LTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQ 1413
Cdd:TIGR01188   81 LTGRENLEMMGRLYGLPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTR 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1414 QQMWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFGKDYlLEMKVKNLAQVEPLHAEIL 1493
Cdd:TIGR01188  161 RAIWDYIRA-LKEEGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRRLGKDT-LESRPRDIQSLKVEVSMLI 238
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6005701    1494 RLFP--QAARQERYSSLMVYKLPVEDVQPLAQAFFKlEKVKQSFDLEEYSLSQSTLEQVFLEL 1554
Cdd:TIGR01188  239 AELGetGLGLLAVTVDSDRIKILVPDGDETVPEIVE-AAIRNGIRIRSISTERPSLDDVFLKL 300
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
1240-1466 1.28e-50

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 178.72  E-value: 1.28e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1240 IIASCLRKEYAGKRkgcfskrknkiATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGG 1315
Cdd:cd03265    1 IEVENLVKKYGDFE-----------AVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGhdvvREPR 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1316 DALEFLGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGN 1395
Cdd:cd03265   70 EVRRRIGIVFQDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHR 149
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701  1396 PSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLK 1466
Cdd:cd03265  150 PEVLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEELK 220
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
480-658 2.65e-50

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 178.33  E-value: 2.65e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEmaDLENLSKL 559
Cdd:COG1131    1 IEVRGLTKRYGDKT----ALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVAR--DPAEVRRR 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDK----------------------------------------EIFL 599
Cdd:COG1131   75 IGYVPQEPALYPDLTVRENLRFFARLYGLPRKEAREridellelfgltdaadrkvgtlsggmkqrlglalallhdpELLI 154
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   600 LDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:COG1131  155 LDEPTSGLDPEARRELWELLRElAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGT 214
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
480-653 2.03e-47

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 167.57  E-value: 2.03e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEmaDLENLSKL 559
Cdd:cd03230    1 IEVRNLSKRYGKKT----ALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKK--EPEEVKRR 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFLTVRENLRL-------FAKIKGILpqeVDKEIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFS 631
Cdd:cd03230   75 IGYLPEEPSLYENLTVRENLKLsggmkqrLALAQALL---HDPELLILDEPTSGLDPESRREFWELLRElKKEGKTILLS 151
                        170       180
                 ....*....|....*....|..
gi 6005701   632 TQFMDEADILADRKVFLSQGKL 653
Cdd:cd03230  152 SHILEEAERLCDRVAILNNGRI 173
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
1257-1460 3.65e-47

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 168.23  E-value: 3.65e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1257 FSKR-KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDAL-EFLGYCPQENALWPNL 1334
Cdd:cd03269    6 VTKRfGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAArNRIGYLPEERGLYPKM 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1335 TVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQ 1414
Cdd:cd03269   86 KVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVE 165
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 6005701  1415 QMWQAIRATFRNtERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIG 1460
Cdd:cd03269  166 LLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
1258-1457 1.63e-45

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 163.52  E-value: 1.63e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1258 SKR-KNKIATRNVSFCVRKGeVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG---SGGGDAL-EFLGYCPQENALWP 1332
Cdd:cd03264    7 TKRyGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGqdvLKQPQKLrRRIGYLPQEFGVYP 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1333 NLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEg 1412
Cdd:cd03264   86 NFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAGLDPE- 164
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 6005701  1413 qqqmwQAIRatFRN------TERGALLTTHYMAEAEAVCDRVAIMVSGRLR 1457
Cdd:cd03264  165 -----ERIR--FRNllselgEDRIVILSTHIVEDVESLCNQVAVLNKGKLV 208
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
1239-1518 2.84e-45

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 166.80  E-value: 2.84e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1239 VIIASCLRKEY---------AGKRKGCFSKRKNKI-ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVl 1308
Cdd:COG4586    1 IIEVENLSKTYrvyekepglKGALKGLFRREYREVeAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEV- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1309 lkgsgggdalEFLGYCP----------------QENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLK 1372
Cdd:COG4586   80 ----------RVLGYVPfkrrkefarrigvvfgQRSQLWWDLPAIDSFRLLKAIYRIPDAEYKKRLDELVELLDLGELLD 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1373 SPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRAtfRNTERGA--LLTTHYMAEAEAVCDRVAI 1450
Cdd:COG4586  150 TPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKE--YNRERGTtiLLTSHDMDDIEALCDRVIV 227
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701  1451 MVSGRLRCIGSIQHLKSKFGKDYLLEMKVKNLAQVEPL--HAEILRLFPQAAR-----QERYSSLMVY---KLPVEDV 1518
Cdd:COG4586  228 IDHGRIIYDGSLEELKERFGPYKTIVLELAEPVPPLELprGGEVIEREGNRVRlevdpRESLAEVLARllaRYPVRDL 305
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
1256-1457 4.07e-45

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 162.39  E-value: 4.07e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1256 CFSKR-KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGD---ALEFLGYCPQENALW 1331
Cdd:cd03268    5 DLTKTyGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKnieALRRIGALIEAPGFY 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1332 PNLTVRQHLEVYAAVKGLRKGDAEvaitRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPE 1411
Cdd:cd03268   85 PNLTARENLRLLARLLGIRKKRID----EVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGLDPD 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 6005701  1412 GQQQMWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR 1457
Cdd:cd03268  161 GIKELRELILS-LRDQGITVLISSHLLSEIQKVADRIGIINKGKLI 205
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
480-658 4.54e-41

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 151.93  E-value: 4.54e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIyNNKLSEMADLENLSKL 559
Cdd:COG4555    2 IEVENLSKKYGKVP----ALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILI-DGEDVRKEPREARRQI 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 tGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDK----------------------------------------EIFL 599
Cdd:COG4555   77 -GVLPDERGLYDRLTVRENIRYFAELYGLFDEELKKrieeliellgleefldrrvgelstgmkkkvalaralvhdpKVLL 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   600 LDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:COG4555  156 LDEPTNGLDVMARRLLREILRAlKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGS 215
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
1263-1555 1.35e-40

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 152.65  E-value: 1.35e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1263 KIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFLGYCPQENALWPNLTVRQ 1338
Cdd:PRK13537   20 KLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGepvpSRARHARQRVGVVPQFDNLDPDFTVRE 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1339 HLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQ 1418
Cdd:PRK13537  100 NLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDPQARHLMWE 179
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1419 AIRATFrntERGA--LLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHL-KSKFGKDyLLEMKVKNLAQVEPLhaeilrL 1495
Cdd:PRK13537  180 RLRSLL---ARGKtiLLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALiESEIGCD-VIEIYGPDPVALRDE------L 249
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   1496 FPQAARQE-RYSSLMVYklpVEDVQPLAQAffklekVKQSFDLeEYSLSQSTLEQVFLELS 1555
Cdd:PRK13537  250 APLAERTEiSGETLFCY---VRDPEPLHAR------LKGRAGL-RYLHRPANLEDVFLRLT 300
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
1259-1460 1.32e-39

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 146.74  E-value: 1.32e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1259 KRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFLGYCPQENALWPNL 1334
Cdd:cd03266   14 VKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGfdvvKEPAEARRRLGFVSDSTGLYDRL 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1335 TVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQ 1414
Cdd:cd03266   94 TARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLDEPTTGLDVMATR 173
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 6005701  1415 QMWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIG 1460
Cdd:cd03266  174 ALREFIRQ-LRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
1267-1436 2.83e-39

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 145.31  E-value: 2.83e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALEF----LGYCPQENALWPNLTVRQHLEV 1342
Cdd:COG4133   19 SGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDyrrrLAYLGHADGLKPELTVRENLRF 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1343 YAAVKGLRKGDAevAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRA 1422
Cdd:COG4133   99 WAALYGLRADRE--AIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFTALDAAGVALLAELIAA 176
                        170
                 ....*....|....
gi 6005701  1423 tFRNTERGALLTTH 1436
Cdd:COG4133  177 -HLARGGAVLLTTH 189
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
1268-1561 1.19e-38

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 159.02  E-value: 1.19e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1268 NVSFcvRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALEF----LGYCPQENALWPNLTVRQHLEVY 1343
Cdd:TIGR01257  950 NITF--YENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNLDAvrqsLGMCPQHNILFHHLTVAEHILFY 1027
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1344 AAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIrAT 1423
Cdd:TIGR01257 1028 AQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLL-LK 1106
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1424 FRnTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFGKDYLLEM--KVKNL------------------- 1482
Cdd:TIGR01257 1107 YR-SGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLvrKMKNIqsqrggcegtcsctskgfs 1185
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1483 ----AQVEPLHAE-------------ILRLFPQAARQERYSSLMVYKLPVEDVQPLAQA--FFKLEKVKQSFDLEEYSLS 1543
Cdd:TIGR01257 1186 trcpARVDEITPEqvldgdvnelmdlVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYAslFRELEETLADLGLSSFGIS 1265
                          330
                   ....*....|....*...
gi 6005701    1544 QSTLEQVFLELSKEQELG 1561
Cdd:TIGR01257 1266 DTPLEEIFLKVTEDADSG 1283
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
1262-1455 1.06e-36

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 142.66  E-value: 1.06e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1262 NKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFLGYCPQENALWPNLTVR 1337
Cdd:PRK13536   53 DKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGvpvpARARLARARIGVVPQFDNLDLEFTVR 132
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1338 QHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMW 1417
Cdd:PRK13536  133 ENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLIW 212
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 6005701   1418 QAIRATFrntERGA--LLTTHYMAEAEAVCDRVAIMVSGR 1455
Cdd:PRK13536  213 ERLRSLL---ARGKtiLLTTHFMEEAERLCDRLCVLEAGR 249
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
1240-1456 1.62e-36

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 138.62  E-value: 1.62e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1240 IIASCLRKEYAGKRKGCF----------SKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVll 1309
Cdd:cd03267    1 IEVSNLSKSYRVYSKEPGligslkslfkRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEV-- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1310 kgsgggdalEFLGYCP----------------QENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKS 1373
Cdd:cd03267   79 ---------RVAGLVPwkrrkkflrrigvvfgQKTQLWWDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDT 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1374 PVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVS 1453
Cdd:cd03267  150 PVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDK 229

                 ...
gi 6005701  1454 GRL 1456
Cdd:cd03267  230 GRL 232
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
480-653 5.31e-36

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 136.47  E-value: 5.31e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLEnLSKL 559
Cdd:cd03255    1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKE-LAAF 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 ----TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEV----------------------------------------DK 595
Cdd:cd03255   80 rrrhIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERreraeellervglgdrlnhypselsggqqqrvaiaralanDP 159
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   596 EIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADiLADRKVFLSQGKL 653
Cdd:cd03255  160 KIILADEPTGNLDSETGKEVMELLRElnKEAGTTIVVVTHDPELAE-YADRIIELRDGKI 218
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
1267-1406 1.46e-34

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 129.69  E-value: 1.46e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-SGGGDALEFL----GYCPQENALWPNLTVRQHLE 1341
Cdd:pfam00005    2 KNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGqDLTDDERKSLrkeiGYVFQDPQLFPRLTVRENLR 81
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701    1342 VYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPV----KTLSEGIKRKLCFVLSILGNPSVVLLDEPST 1406
Cdd:pfam00005   82 LGLLLKGLSKREKDARAEEALEKLGLGDLADRPVgerpGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
1265-1455 3.85e-34

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 131.40  E-value: 3.85e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-------------SGggdalefLGYCPQENALW 1331
Cdd:cd03224   15 ILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGrditglppherarAG-------IGYVPEGRRIF 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1332 PNLTVRQHLEVYAAVKGLRKGDAEVAitRLVDAL-KLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDP 1410
Cdd:cd03224   88 PELTVEENLLLGAYARRRAKRKARLE--RVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAP 165
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 6005701  1411 EGQQQMWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGR 1455
Cdd:cd03224  166 KIVEEIFEAIR-ELRDEGVTILLVEQNARFALEIADRAYVLERGR 209
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
480-652 1.29e-33

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 127.88  E-value: 1.29e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPDKIeaLKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMaDLENLSKL 559
Cdd:cd03228    1 IEFKNVSFSYPGRPKPV--LKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDL-DLESLRKN 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFlTVRENL------------RLFAKikgilpqevDKEIFLLDEPTAGLDPFSRHQVWNLLKERKTDRV 627
Cdd:cd03228   78 IAYVPQDPFLFSG-TIRENIlsggqrqriaiaRALLR---------DPPILILDEATSALDPETEALILEALRALAKGKT 147
                        170       180
                 ....*....|....*....|....*
gi 6005701   628 ILFSTQFMDEADiLADRKVFLSQGK 652
Cdd:cd03228  148 VIVIAHRLSTIR-DADRIIVLDDGR 171
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
1265-1456 2.77e-33

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 129.09  E-value: 2.77e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----------SGGGDALEFlgycpQENALWPN 1333
Cdd:cd03219   15 ALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGeditglppheiARLGIGRTF-----QIPRLFPE 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1334 LTVRQHLEV--------YAAVKGLRKGDAEV--AITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDE 1403
Cdd:cd03219   90 LTVLENVMVaaqartgsGLLLARARREEREAreRAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDE 169
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 6005701  1404 PSTGMDPEGQQQMWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:cd03219  170 PAAGLNPEETEELAELIRE-LRERGITVLLVEHDMDVVMSLADRVTVLDQGRV 221
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
480-658 6.05e-33

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 128.22  E-value: 6.05e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYkgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEmADLENLSKL 559
Cdd:COG1122    1 IELENLSFSY---PGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITK-KNLRELRRK 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQ-SNVQFDFLTVRENLrLFA-KIKGILPQEVDK----------------------------------------EI 597
Cdd:COG1122   77 VGLVFQnPDDQLFAPTVEEDV-AFGpENLGLPREEIRErveealelvglehladrpphelsggqkqrvaiagvlamepEV 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701   598 FLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:COG1122  156 LVLDEPTAGLDPRGRRELLELLKRlNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGT 217
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
481-652 7.34e-33

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 125.05  E-value: 7.34e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   481 RIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMaDLENLSKLT 560
Cdd:cd00267    1 EIENLSFRYGGRT----ALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKL-PLEELRRRI 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   561 GVCPQsnvqfdfLTVRENLRL-FAKIKGILPqevdkEIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEA 638
Cdd:cd00267   76 GYVPQ-------LSGGQRQRVaLARALLLNP-----DLLLLDEPTSGLDPASRERLLELLRElAEEGRTVIIVTHDPELA 143
                        170
                 ....*....|....
gi 6005701   639 DILADRKVFLSQGK 652
Cdd:cd00267  144 ELAADRVIVLKDGK 157
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
1259-1455 1.47e-32

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 126.43  E-value: 1.47e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1259 KRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----SGGGDALEFLGYCPQEnalwP- 1332
Cdd:cd03225   10 PDGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGkdltkLSLKELRRKVGLVFQN----Pd 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1333 ----NLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCfVLSIL-GNPSVVLLDEPSTG 1407
Cdd:cd03225   86 dqffGPTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVA-IAGVLaMDPDILLLDEPTAG 164
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 6005701  1408 MDPEGQQQMWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGR 1455
Cdd:cd03225  165 LDPAGRRELLELLK-KLKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
480-649 5.77e-32

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 124.89  E-value: 5.77e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEmadlenLSKL 559
Cdd:cd03293    1 LEVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTG------PGPD 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQE----------------------------------------VDKEIFL 599
Cdd:cd03293   75 RGYVFQQDALLPWLTVLDNVALGLELQGVPKAEareraeellelvglsgfenayphqlsggmrqrvalaralaVDPDVLL 154
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 6005701   600 LDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLS 649
Cdd:cd03293  155 LDEPFSALDALTREQLQEELLDiwRETGKTVLLVTHDIDEAVFLADRVVVLS 206
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
1257-1460 6.89e-32

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 124.55  E-value: 6.89e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1257 FSKR-KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG---SGGGDALEFLGYCPQENALWP 1332
Cdd:cd03259    6 LSKTyGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGrdvTGVPPERRNIGMVFQDYALFP 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1333 NLTVRQHLeVYA-AVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPE 1411
Cdd:cd03259   86 HLTVAENI-AFGlKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSALDAK 164
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 6005701  1412 GQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIG 1460
Cdd:cd03259  165 LREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
479-651 1.06e-31

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 125.59  E-value: 1.06e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   479 AIRIRNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEmadlenLSK 558
Cdd:COG1116    7 ALELRGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTG------PGP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   559 LTGVCPQSNVQFDFLTVRENLRLFAKIKGILPQE----------------------------------------VDKEIF 598
Cdd:COG1116   81 DRGVVFQEPALLPWLTVLDNVALGLELRGVPKAErrerarellelvglagfedayphqlsggmrqrvaiaralaNDPEVL 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701   599 LLDEPTAGLDPFSRHQVWNLL-----KERKTdrvILFSTQFMDEADILADRKVFLSQG 651
Cdd:COG1116  161 LMDEPFGALDALTRERLQDELlrlwqETGKT---VLFVTHDVDEAVFLADRVVVLSAR 215
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
1267-1476 2.06e-31

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 123.60  E-value: 2.06e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----SGGGDALEFLGYCPQ--ENALWpNLTVRQh 1339
Cdd:COG1122   18 DDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGkditkKNLRELRRKVGLVFQnpDDQLF-APTVEE- 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1340 lEV-YAAV-KGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCF--VLSIlgNPSVVLLDEPSTGMDPEGQQQ 1415
Cdd:COG1122   96 -DVaFGPEnLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIagVLAM--EPEVLVLDEPTAGLDPRGRRE 172
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701  1416 MWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLkskFGKDYLLE 1476
Cdd:COG1122  173 LLELLKR-LNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREV---FSDYELLE 229
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
494-752 2.09e-31

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 125.97  E-value: 2.09e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     494 DKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLenLSKLTGVCPQSNVQFDFL 573
Cdd:TIGR01188    4 GDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDVVREPRK--VRRSIGIVPQYASVDEDL 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     574 TVRENLRLFAKIKGILPQEVDK----------------------------------------EIFLLDEPTAGLDPFSRH 613
Cdd:TIGR01188   82 TGRENLEMMGRLYGLPKDEAEEraeellelfelgeaadrpvgtysggmrrrldiaaslihqpDVLFLDEPTTGLDPRTRR 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     614 QVWNLLKERKTDRV-ILFSTQFMDEADILADRKVFLSQGKLKCAGSSLFLKKKWGiGYHLSLQLNEICVEENITSLVKQH 692
Cdd:TIGR01188  162 AIWDYIRALKEEGVtILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRRLG-KDTLESRPRDIQSLKVEVSMLIAE 240
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701     693 IPDAKLSAK-----SEGKLIYTLPLERTnkFPELYKDLDSYpdlGIENYGVSMT--TLNEVFLKLEG 752
Cdd:TIGR01188  241 LGETGLGLLavtvdSDRIKILVPDGDET--VPEIVEAAIRN---GIRIRSISTErpSLDDVFLKLTG 302
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
1265-1456 2.40e-31

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 124.38  E-value: 2.40e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----------SGGGDALEFlgycpQENALWPN 1333
Cdd:COG0411   19 AVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGrditglpphriARLGIARTF-----QNPRLFPE 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1334 LTVRQHLEV----------YAAVKGLRKGDAEVAITR-----LVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSV 1398
Cdd:COG0411   94 LTVLENVLVaaharlgrglLAALLRLPRARREEREAReraeeLLERVGLADRADEPAGNLSYGQQRRLEIARALATEPKL 173
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1399 VLLDEPSTGMDPEGQQQMWQAIRATfrNTERGA--LLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:COG0411  174 LLLDEPAAGLNPEETEELAELIRRL--RDERGItiLLIEHDMDLVMGLADRIVVLDFGRV 231
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
1258-1461 1.47e-30

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 121.11  E-value: 1.47e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1258 SKR-KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsGGGD---------ALEFLGYCPQE 1327
Cdd:cd03218    7 SKRyGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILL---DGQDitklpmhkrARLGIGYLPQE 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1328 NALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTG 1407
Cdd:cd03218   84 ASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEPFAG 163
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 6005701  1408 MDPEGQQQMwQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:cd03218  164 VDPIAVQDI-QKIIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGT 216
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
1262-1464 1.47e-30

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 121.73  E-value: 1.47e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1262 NKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALEFLGYCPQENAL-W--PnLTVRq 1338
Cdd:COG1121   18 GRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRRIGYVPQRAEVdWdfP-ITVR- 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1339 hlEV-----YAAV---KGLRKGDAEvAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDP 1410
Cdd:COG1121   96 --DVvlmgrYGRRglfRRPSRADRE-AVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDPDLLLLDEPFAGVDA 172
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 6005701  1411 EGQQQMWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVaIMVSGRLRCIGSIQH 1464
Cdd:COG1121  173 ATEEALYELLRE-LRREGKTILVVTHDLGAVREYFDRV-LLLNRGLVAHGPPEE 224
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
480-653 2.26e-30

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 120.01  E-value: 2.26e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIynnKLSEMADLENLSKL 559
Cdd:cd03268    1 LKTNDLTKTYGKKR----VLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITF---DGKSYQKNIEALRR 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDK------------------------------------EIFLLDEP 603
Cdd:cd03268   74 IGALIEAPGFYPNLTARENLRLLARLLGIRKKRIDEvldvvglkdsakkkvkgfslgmkqrlgialallgnpDLLILDEP 153
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 6005701   604 TAGLDPFSRHQVWNLL-KERKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:cd03268  154 TNGLDPDGIKELRELIlSLRDQGITVLISSHLLSEIQKVADRIGIINKGKL 204
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
1259-1455 2.44e-30

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 118.12  E-value: 2.44e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1259 KRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGD-----ALEFLGYCPQenalwpn 1333
Cdd:cd00267    8 RYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKlpleeLRRRIGYVPQ------- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1334 ltvrqhlevyaavkglrkgdaevaitrlvdalklqdqlkspvktLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQ 1413
Cdd:cd00267   81 --------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTSGLDPASR 116
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 6005701  1414 QQMWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGR 1455
Cdd:cd00267  117 ERLLELLRE-LAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
480-652 2.74e-30

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 118.44  E-value: 2.74e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMAD-LENLSK 558
Cdd:cd03229    1 LELKNVSKRYGQKT----VLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDeLPPLRR 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   559 LTGVCPQSNVQFDFLTVRENLRLfaKIKGILPQEV--------DKEIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVI 628
Cdd:cd03229   77 RIGMVFQDFALFPHLTVLENIAL--GLSGGQQQRValaralamDPDVLLLDEPTSALDPITRREVRALLKSlqAQLGITV 154
                        170       180
                 ....*....|....*....|....
gi 6005701   629 LFSTQFMDEADILADRKVFLSQGK 652
Cdd:cd03229  155 VLVTHDLDEAARLADRVVVLRDGK 178
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
477-653 3.45e-30

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 120.15  E-value: 3.45e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   477 KEAIRIRNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADlENL 556
Cdd:COG1136    2 SPLLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSE-REL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   557 SKL----TGVCPQS-NVqFDFLTVRENLRLFAKIKGILPQEVDK------------------------------------ 595
Cdd:COG1136   81 ARLrrrhIGFVFQFfNL-LPELTALENVALPLLLAGVSRKERRErarellervglgdrldhrpsqlsggqqqrvaiaral 159
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701   596 ----EIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADIlADRKVFLSQGKL 653
Cdd:COG1136  160 vnrpKLILADEPTGNLDSKTGEEVLELLRElnRELGTTIVMVTHDPELAAR-ADRVIRLRDGRI 222
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
480-654 4.04e-30

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 119.22  E-value: 4.04e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKpdkiEALKDLVFDIYEGqITAILGHSGAGKSTLLNILSGLSVPTKGSVTIynNKLSEMADLENLSKL 559
Cdd:cd03264    1 LQLENLTKRYGKK----RALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRI--DGQDVLKQPQKLRRR 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDKE----------------------------------------IFL 599
Cdd:cd03264   74 IGYLPQEFGVYPNFTVREFLDYIAWLKGIPSKEVKARvdevlelvnlgdrakkkigslsggmrrrvgiaqalvgdpsILI 153
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 6005701   600 LDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADILADRKVFLSQGKLK 654
Cdd:cd03264  154 VDEPTAGLDPEERIRFRNLLSELGEDRIVILSTHIVEDVESLCNQVAVLNKGKLV 208
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
480-653 5.91e-30

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 119.53  E-value: 5.91e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEM--ADLENLS 557
Cdd:cd03261    1 IELRGLTKSFGGRT----VLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLseAELYRLR 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   558 KLTGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEV-----------------------------------------DKE 596
Cdd:cd03261   77 RRMGMLFQSGALFDSLTVFENVAFPLREHTRLSEEEireivlekleavglrgaedlypaelsggmkkrvalaralalDPE 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   597 IFLLDEPTAGLDPFSRHQVWNL---LKERKTDRVILFSTQfMDEADILADRKVFLSQGKL 653
Cdd:cd03261  157 LLLYDEPTAGLDPIASGVIDDLirsLKKELGLTSIMVTHD-LDTAFAIADRIAVLYDGKI 215
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
480-663 9.31e-30

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 118.63  E-value: 9.31e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYkgkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIynNKLSEMADLENLSKL 559
Cdd:cd03265    1 IEVENLVKKY----GDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATV--AGHDVVREPREVRRR 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDK----------------------------------------EIFL 599
Cdd:cd03265   75 IGIVFQDLSVDDELTGWENLYIHARLYGVPGAERREridelldfvglleaadrlvktysggmrrrleiarslvhrpEVLF 154
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701   600 LDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGSSLFLK 663
Cdd:cd03265  155 LDEPTIGLDPQTRAHVWEYIEKlkEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEELK 220
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
1259-1460 1.33e-29

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 118.40  E-value: 1.33e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1259 KRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVllKGSGGGDALEFLGYcpqenALWPNLTVRQ 1338
Cdd:cd03220   31 EVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTV--TVRGRVSSLLGLGG-----GFNPELTGRE 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1339 HLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEP-STGmDPEGQQQMW 1417
Cdd:cd03220  104 NIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVlAVG-DAAFQEKCQ 182
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 6005701  1418 QAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIG 1460
Cdd:cd03220  183 RRLR-ELLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
1266-1460 2.16e-29

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 117.40  E-value: 2.16e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1266 TRNVSFCVrKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALEFL---------GYCPQENALWPNLTV 1336
Cdd:cd03297   14 TLKIDFDL-NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSRKKInlppqqrkiGLVFQQYALFPHLNV 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1337 RQHLEVyaAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQM 1416
Cdd:cd03297   93 RENLAF--GLKRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQL 170
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 6005701  1417 WQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIG 1460
Cdd:cd03297  171 LPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
1267-1455 3.11e-29

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 117.39  E-value: 3.11e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-------------SGggdalefLGYCPQENALWPN 1333
Cdd:COG0410   20 HGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGeditglpphriarLG-------IGYVPEGRRIFPS 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1334 LTVRQHLEVYAAVKGLRKGDAEvaitRL--VDAL--KLQDQLKSPVKTLSEG------IKRKLcfvlsiLGNPSVVLLDE 1403
Cdd:COG0410   93 LTVEENLLLGAYARRDRAEVRA----DLerVYELfpRLKERRRQRAGTLSGGeqqmlaIGRAL------MSRPKLLLLDE 162
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 6005701  1404 PSTGMDPEGQQQMWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGR 1455
Cdd:COG0410  163 PSLGLAPLIVEEIFEIIR-RLNREGVTILLVEQNARFALEIADRAYVLERGR 213
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
1262-1460 4.31e-29

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 116.48  E-value: 4.31e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1262 NKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALEFLGYCPQ-ENALW--PnLTVRQ 1338
Cdd:cd03235   11 GHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKERKRIGYVPQrRSIDRdfP-ISVRD 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1339 --------HLEVYAAVKGLRKGDAEVAITRlVDALKLQDQlksPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDP 1410
Cdd:cd03235   90 vvlmglygHKGLFRRLSKADKAKVDEALER-VGLSELADR---QIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGVDP 165
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 6005701  1411 EGQQQMWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVaIMVSGRLRCIG 1460
Cdd:cd03235  166 KTQEDIYELLR-ELRREGMTILVVTHDLGLVLEYFDRV-LLLNRTVVASG 213
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
483-653 4.45e-29

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 115.73  E-value: 4.45e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   483 RNVTKEYKGKPDKIEA--LKDLVFDIYEGQITAILGHSGAGKSTLLNILSGL--SVPTKGSVTIyNNKlseMADLENLSK 558
Cdd:cd03213    7 RNLTVTVKSSPSKSGKqlLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRrtGLGVSGEVLI-NGR---PLDKRSFRK 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   559 LTGVCPQSNVQFDFLTVRENLRLFAKIKGI---------LPQEVDKE--IFLLDEPTAGLDPFSRHQVWNLLKE-RKTDR 626
Cdd:cd03213   83 IIGYVPQDDILHPTLTVRETLMFAAKLRGLsggerkrvsIALELVSNpsLLFLDEPTSGLDSSSALQVMSLLRRlADTGR 162
                        170       180
                 ....*....|....*....|....*...
gi 6005701   627 VILFST-QFMDEADILADRKVFLSQGKL 653
Cdd:cd03213  163 TIICSIhQPSSEIFELFDKLLLLSQGRV 190
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
1247-1462 4.47e-29

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 117.49  E-value: 4.47e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1247 KEYAGKRKGcfSKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS-------GGGdale 1319
Cdd:COG1134   25 KELLLRRRR--TRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGRvsallelGAG---- 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1320 FLgycpqenalwPNLTVRQHLEVYAAVKGLRKGDaevaITRLVDALK----LQDQLKSPVKTLSEGIKRKLCFVLSILGN 1395
Cdd:COG1134   99 FH----------PELTGRENIYLNGRLLGLSRKE----IDEKFDEIVefaeLGDFIDQPVKTYSSGMRARLAFAVATAVD 164
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701  1396 PSVVLLDEP-STGmDPEGQQQMWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSI 1462
Cdd:COG1134  165 PDILLVDEVlAVG-DAAFQKKCLARIRE-LRESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDP 230
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
1267-1461 1.50e-28

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 116.30  E-value: 1.50e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsgGGDALE---------FLGYCPQENALWPNLTVR 1337
Cdd:COG1120   18 DDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLL----DGRDLAslsrrelarRIAYVPQEPPAPFGLTVR 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1338 Q--------HLevyAAVKGLRKGDAEVAIT--RLVDALKLQDQlksPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTG 1407
Cdd:COG1120   94 ElvalgrypHL---GLFGRPSAEDREAVEEalERTGLEHLADR---PVDELSGGERQRVLIARALAQEPPLLLLDEPTSH 167
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 6005701  1408 MDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:COG1120  168 LDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGP 221
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
481-652 2.35e-28

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 114.10  E-value: 2.35e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   481 RIRNVTKEYKGKpdKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMaDLENLSKLT 560
Cdd:cd03225    1 ELKNLSFSYPDG--ARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKL-SLKELRRKV 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   561 GVCPQ-SNVQFDFLTVRENLrLFA-KIKGILPQEVDK----------------------------------------EIF 598
Cdd:cd03225   78 GLVFQnPDDQFFGPTVEEEV-AFGlENLGLPEEEIEErveealelvgleglrdrspftlsggqkqrvaiagvlamdpDIL 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 6005701   599 LLDEPTAGLDPFSRHQVWNLLKERKTDRV-ILFSTQFMDEADILADRKVFLSQGK 652
Cdd:cd03225  157 LLDEPTAGLDPAGRRELLELLKKLKAEGKtIIIVTHDLDLLLELADRVIVLEDGK 211
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
1238-1461 1.44e-27

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 112.82  E-value: 1.44e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1238 PVIIASCLRKEYaGKRKgcfskrknkiATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSgggD- 1316
Cdd:COG1137    2 MTLEAENLVKSY-GKRT----------VVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGE---Di 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1317 --------ALEFLGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCF 1388
Cdd:COG1137   68 thlpmhkrARLGIGYLPQEASIFRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEI 147
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701  1389 VLSILGNPSVVLLDEPSTGMDP---EGQQQMwqaIRatfRNTERGA--LLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:COG1137  148 ARALATNPKFILLDEPFAGVDPiavADIQKI---IR---HLKERGIgvLITDHNVRETLGICDRAYIISEGKVLAEGT 219
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
453-672 2.41e-27

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 119.10  E-value: 2.41e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   453 LEDEMDADPSfhDSFEQAPPEFQGKEAIRIRNVTKEYKGKPDkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGL 532
Cdd:COG4987  309 LNELLDAPPA--VTEPAEPAPAPGGPSLELEDVSFRYPGAGR--PVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRF 384
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   533 SVPTKGSVTIYNNKLSEMaDLENLSKLTGVCPQSNVQFDfLTVRENLRLfAK--------------------IKGiLPQE 592
Cdd:COG4987  385 LDPQSGSITLGGVDLRDL-DEDDLRRRIAVVPQRPHLFD-TTLRENLRL-ARpdatdeelwaalervglgdwLAA-LPDG 460
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   593 VD---------------------------KEIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADiLADRK 645
Cdd:COG4987  461 LDtwlgeggrrlsggerrrlalarallrdAPILLLDEPTEGLDAATEQALLADLLEALAGRTVLLITHRLAGLE-RMDRI 539
                        250       260
                 ....*....|....*....|....*..
gi 6005701   646 VFLSQGKLKCAGSSLFLKKKWGIGYHL 672
Cdd:COG4987  540 LVLEDGRIVEQGTHEELLAQNGRYRQL 566
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
1257-1455 2.93e-27

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 109.97  E-value: 2.93e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1257 FSKR-KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEF---LGYCPQEN 1328
Cdd:cd03229    6 VSKRyGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGedltDLEDELPPLrrrIGMVFQDF 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1329 ALWPNLTVRQHLeVYAavkglrkgdaevaitrlvdalklqdqlkspvktLSEGIKRKLCFVLSILGNPSVVLLDEPSTGM 1408
Cdd:cd03229   86 ALFPHLTVLENI-ALG---------------------------------LSGGQQQRVALARALAMDPDVLLLDEPTSAL 131
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 6005701  1409 DPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGR 1455
Cdd:cd03229  132 DPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
480-657 3.23e-27

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 111.31  E-value: 3.23e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEmADLENLSKL 559
Cdd:cd03266    2 ITADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVK-EPAEARRRL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 tGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEV----------------------------------------DKEIFL 599
Cdd:cd03266   81 -GFVSDSTGLYDRLTARENLEYFAGLYGLKGDELtarleeladrlgmeelldrrvggfstgmrqkvaiaralvhDPPVLL 159
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701   600 LDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAG 657
Cdd:cd03266  160 LDEPTTGLDVMATRALREFIRQlRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
479-658 5.11e-27

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 111.22  E-value: 5.11e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   479 AIRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEM--ADLENL 556
Cdd:COG1127    5 MIEVRNLTKSFGDRV----VLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLseKELYEL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   557 SKLTGVCPQSNVQFDFLTVREN----LRLF-----AKIKGI---------LPQEVDK----------------------- 595
Cdd:COG1127   81 RRRIGMLFQGGALFDSLTVFENvafpLREHtdlseAEIRELvleklelvgLPGAADKmpselsggmrkrvalaralaldp 160
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701   596 EIFLLDEPTAGLDPFSRHQVWNLLKERKTDR---VILFSTQfMDEADILADRKVFLSQGKLKCAGS 658
Cdd:COG1127  161 EILLYDEPTAGLDPITSAVIDELIRELRDELgltSVVVTHD-LDSAFAIADRVAVLADGKIIAEGT 225
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
1265-1465 6.18e-27

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 117.31  E-value: 6.18e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTA---GQVLLKGSGGGDALEFL-----GYCPQE--NALWPnL 1334
Cdd:COG1123   21 AVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGGrisGEVLLDGRDLLELSEALrgrriGMVFQDpmTQLNP-V 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1335 TVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQ 1414
Cdd:COG1123  100 TVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDLLIADEPTTALDVTTQA 179
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 6005701  1415 QMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHL 1465
Cdd:COG1123  180 EILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEI 230
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
1240-1455 9.99e-27

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 109.87  E-value: 9.99e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1240 IIASCLRKEYAGKRKGcfskrknKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG---SGGGD 1316
Cdd:cd03293    1 LEVRNVSKTYGGGGGA-------VTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGepvTGPGP 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1317 AlefLGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNP 1396
Cdd:cd03293   74 D---RGYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDP 150
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701  1397 SVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMvSGR 1455
Cdd:cd03293  151 DVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVL-SAR 208
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
480-653 1.57e-26

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 109.58  E-value: 1.57e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYkgkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGL-----SVPTKGSVTIYN-NKLSEMADL 553
Cdd:cd03260    1 IELRDLNVYY----GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLndlipGAPDEGEVLLDGkDIYDLDVDV 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   554 ENLSKLTGVCPQSNVQFDfLTVRENLRLFAKIKGI------------------LPQEVDK-------------------- 595
Cdd:cd03260   77 LELRRRVGMVFQKPNPFP-GSIYDNVAYGLRLHGIklkeelderveealrkaaLWDEVKDrlhalglsggqqqrlclara 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6005701   596 -----EIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:cd03260  156 lanepEVLLLDEPTSALDPISTAKIEELIAELKKEYTIVIVTHNMQQAARVADRTAFLLNGRL 218
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
481-657 5.17e-26

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 106.37  E-value: 5.17e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   481 RIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLEnLSKLT 560
Cdd:cd03214    1 EVENLSVGYGGRT----VLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKE-LARKI 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   561 GVCPQSNVQFDFLTVREnlRLFAKIKG----------ILPQEVDkeIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVI 628
Cdd:cd03214   76 AYVPQALELLGLAHLAD--RPFNELSGgerqrvllarALAQEPP--ILLLDEPTSHLDIAHQIELLELLRRlaRERGKTV 151
                        170       180
                 ....*....|....*....|....*....
gi 6005701   629 LFSTQFMDEADILADRKVFLSQGKLKCAG 657
Cdd:cd03214  152 VMVLHDLNLAARYADRVILLKDGRIVAQG 180
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
1258-1461 6.61e-26

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 110.96  E-value: 6.61e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1258 SKR-KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsgGGDALEFL-------GYCPQENA 1329
Cdd:COG3842   12 SKRyGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILL----DGRDVTGLppekrnvGMVFQDYA 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1330 LWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEG------IKRKLCFvlsilgNPSVVLLDE 1403
Cdd:COG3842   88 LFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGqqqrvaLARALAP------EPRVLLLDE 161
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701  1404 PSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:COG3842  162 PLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGT 219
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
479-658 7.52e-26

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 108.21  E-value: 7.52e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   479 AIRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLEnLSK 558
Cdd:COG1120    1 MLEAENLSVGYGGRP----VLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRE-LAR 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   559 LTGVCPQSNVQFDFLTVRE--------NLRLFAKikgilPQEVDKE---------------------------------- 596
Cdd:COG1120   76 RIAYVPQEPPAPFGLTVRElvalgrypHLGLFGR-----PSAEDREaveealertglehladrpvdelsggerqrvliar 150
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   597 -------IFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:COG1120  151 alaqeppLLLLDEPTSHLDLAHQLEVLELLRRlaRERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGP 221
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
1257-1456 1.18e-25

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 106.82  E-value: 1.18e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1257 FSKRKNKI-ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG---SGGGDALEFL-----GYCPQE 1327
Cdd:cd03257   11 FPTGGGSVkALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGkdlLKLSRRLRKIrrkeiQMVFQD 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1328 --NALWPNLTVRQHLEvyAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKT-----LSEGIKRKLCFVLSILGNPSVVL 1400
Cdd:cd03257   91 pmSSLNPRMTIGEQIA--EPLRIHGKLSKKEARKEAVLLLLVGVGLPEEVLNrypheLSGGQRQRVAIARALALNPKLLI 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1401 LDEPSTGMDPEGQQQmwqaIRATFRN--TERGA--LLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:cd03257  169 ADEPTSALDVSVQAQ----ILDLLKKlqEELGLtlLFITHDLGVVAKIADRVAVMYAGKI 224
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
469-658 1.40e-25

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 113.70  E-value: 1.40e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   469 QAPPEFQGKEAIRIRNVTKEYkgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLS 548
Cdd:COG4988  326 TAPLPAAGPPSIELEDVSFSY---PGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLS 402
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   549 EMaDLENLSKLTGVCPQSNVQFDfLTVRENLRLF------------AKIKGI------LPQ----EV------------- 593
Cdd:COG4988  403 DL-DPASWRRQIAWVPQNPYLFA-GTIRENLRLGrpdasdeeleaaLEAAGLdefvaaLPDgldtPLgeggrglsggqaq 480
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701   594 ----------DKEIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQfmDEADI-LADRKVFLSQGKLKCAGS 658
Cdd:COG4988  481 rlalarallrDAPLLLLDEPTAHLDAETEAEILQALRRLAKGRTVILITH--RLALLaQADRILVLDDGRIVEQGT 554
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
480-653 1.53e-25

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 106.90  E-value: 1.53e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEM--ADLENLS 557
Cdd:cd03258    2 IELKNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLsgKELRKAR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   558 KLTGVCPQsnvQFDFL---TVRENLRLFAKIKGILPQEVDK--------------------------------------- 595
Cdd:cd03258   82 RRIGMIFQ---HFNLLssrTVFENVALPLEIAGVPKAEIEErvlellelvgledkadaypaqlsggqkqrvgiaralann 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   596 -EIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:cd03258  159 pKVLLCDEATSALDPETTQSILALLRDinRELGLTIVLITHEMEVVKRICDRVAVMEKGEV 219
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
1245-1456 1.87e-25

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 106.03  E-value: 1.87e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1245 LRKEYAGKRKgcfskrkNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG---SGGGDA---- 1317
Cdd:cd03255    6 LSKTYGGGGE-------KVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGtdiSKLSEKelaa 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1318 --LEFLGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEG------IKRklcfv 1389
Cdd:cd03255   79 frRRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGqqqrvaIAR----- 153
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701  1390 lSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAvCDRVAIMVSGRL 1456
Cdd:cd03255  154 -ALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEY-ADRIIELRDGKI 218
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
1235-1465 4.79e-25

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 111.15  E-value: 4.79e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1235 DEKPVIIASCLRKEYAGKRKGCFskrknkIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG--- 1311
Cdd:COG1123  256 AAEPLLEVRNLSKRYPVRGKGGV------RAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGkdl 329
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1312 --SGGGDALEF---LGYCPQ--ENALWPNLTVRQHL-EVYAAVKGLRKGDAEVAITRLVDALKLQDQL--KSPvKTLSEG 1381
Cdd:COG1123  330 tkLSRRSLRELrrrVQMVFQdpYSSLNPRMTVGDIIaEPLRLHGLLSRAERRERVAELLERVGLPPDLadRYP-HELSGG 408
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1382 IKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:COG1123  409 QRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGP 488

                 ....
gi 6005701  1462 IQHL 1465
Cdd:COG1123  489 TEEV 492
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
1235-1474 6.21e-25

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 112.91  E-value: 6.21e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1235 DEKPVIIASCLRKeyagkRKGCFskrknkIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG--- 1311
Cdd:NF033858  262 DDEPAIEARGLTM-----RFGDF------TAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGqpv 330
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1312 -SGGGDALEFLGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVL 1390
Cdd:NF033858  331 dAGDIATRRRVGYMSQAFSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAV 410
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1391 SILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAvCDRVAIMVSGRLRCIGSIQHLKSKFG 1470
Cdd:NF033858  411 AVIHKPELLILDEPTSGVDPVARDMFWRLLIELSREDGVTIFISTHFMNEAER-CDRISLMHAGRVLASDTPAALVAARG 489

                  ....
gi 6005701   1471 KDYL 1474
Cdd:NF033858  490 AATL 493
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
449-672 8.38e-25

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 112.23  E-value: 8.38e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   449 DHVALEDEMDADPSFhdsfeQAPPEFQGkeAIRIRNVTKEYKgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNI 528
Cdd:COG2274  450 DILDLPPEREEGRSK-----LSLPRLKG--DIELENVSFRYP--GDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKL 520
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   529 LSGLSVPTKGSVTIYNNKLSEMaDLENLSKLTGVCPQSNVQFdFLTVRENLRLF------------AKIKGI------LP 590
Cdd:COG2274  521 LLGLYEPTSGRILIDGIDLRQI-DPASLRRQIGVVLQDVFLF-SGTIRENITLGdpdatdeeiieaARLAGLhdfieaLP 598
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   591 Q----EV-----------------------DKEIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQfmDEADI-LA 642
Cdd:COG2274  599 MgydtVVgeggsnlsggqrqrlaiarallrNPRILILDEATSALDAETEAIILENLRRLLKGRTVIIIAH--RLSTIrLA 676
                        250       260       270
                 ....*....|....*....|....*....|
gi 6005701   643 DRKVFLSQGKLKCAGSSLFLKKKWGIGYHL 672
Cdd:COG2274  677 DRIIVLDKGRIVEDGTHEELLARKGLYAEL 706
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
229-755 1.23e-24

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 112.80  E-value: 1.23e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     229 CII---SF--SSFIYYasvnVTRER-KRMKALMTMMGLRDSAFWLS---WGLLyaGFIFIMALFLALVI--RSTQFIILS 297
Cdd:TIGR01257 1685 CVIfamSFvpASFVLY----LIQERvNKAKHLQFISGVSPTTYWLTnflWDIM--NYAVSAGLVVGIFIgfQKKAYTSPE 1758
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     298 GFMVVFSLFLLYGLSLVALAFLMSILVK-----------KSFLTGL----VVFLLTVFWG---CLGFTSLYRHLpaslew 359
Cdd:TIGR01257 1759 NLPALVALLMLYGWAVIPMMYPASFLFDvpstayvalscANLFIGInssaITFVLELFENnrtLLRFNAMLRKL------ 1832
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     360 iLSLLSPFAFMLGMAQLL----------HLDYDLNSNAFPHPSDGSNLivatnFMLAFDTCLYLALAIYFEKilpneygh 429
Cdd:TIGR01257 1833 -LIVFPHFCLGRGLIDLAlsqavtdvyaQFGEEHSANPFQWDLIGKNL-----VAMAVEGVVYFLLTLLIQH-------- 1898
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     430 rrppLFFLkssfwsqTQKTDHVALEDEMDADPSFHDSFEQAPPEFQGKEAIRIRNVTKEYKGKPDKieALKDLVFDIYEG 509
Cdd:TIGR01257 1899 ----HFFL-------SRWIAEPAKEPIFDEDDDVAEERQRIISGGNKTDILRLNELTKVYSGTSSP--AVDRLCVGVRPG 1965
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     510 QITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLseMADLENLSKLTGVCPQSNVQFDFLTVRENLRLFAKIKGIL 589
Cdd:TIGR01257 1966 ECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSI--LTNISDVHQNMGYCPQFDAIDDLLTGREHLYLYARLRGVP 2043
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     590 PQEVDK----------------------------------------EIFLLDEPTAGLDPFSRHQVWN-LLKERKTDRVI 628
Cdd:TIGR01257 2044 AEEIEKvanwsiqslglslyadrlagtysggnkrklstaialigcpPLVLLDEPTTGMDPQARRMLWNtIVSIIREGRAV 2123
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     629 LFSTQFMDEADILADRKVFLSQGKLKCAGSSLFLKKKWGIGYHLSLQL----NEICVEEN-ITSLVKQHIPDAKLSAKSE 703
Cdd:TIGR01257 2124 VLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIkspkDDLLPDLNpVEQFFQGNFPGSVQRERHY 2203
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 6005701     704 GKLIYTLPlerTNKFPELYKDLDSYPD-LGIENYGVSMTTLNEVFLKLEGKST 755
Cdd:TIGR01257 2204 NMLQFQVS---SSSLARIFQLLISHKDsLLIEEYSVTQTTLDQVFVNFAKQQT 2253
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
1265-1456 1.55e-24

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 101.74  E-value: 1.55e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSgggdaleflgycpqenalwpnltvrqhlevya 1344
Cdd:cd03216   15 ALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGK-------------------------------- 62
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1345 avkglrkgdaEVAITRLVDALKL------QdqlkspvktLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQ 1418
Cdd:cd03216   63 ----------EVSFASPRDARRAgiamvyQ---------LSVGERQMVEIARALARNARLLILDEPTAALTPAEVERLFK 123
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 6005701  1419 AIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:cd03216  124 VIRR-LRAQGVAVIFISHRLDEVFEIADRVTVLRDGRV 160
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
480-674 1.57e-24

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 105.23  E-value: 1.57e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     480 IRIRNVTKEY-KGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI--YNNKLSEMADLENL 556
Cdd:TIGR04521    1 IKLKNVSYIYqPGTPFEKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIdgRDITAKKKKKLKDL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     557 SKLTGVcpqsnVqFDF-------LTVRE-------NL---------RLFAKIKGI-LPQEV------------------- 593
Cdd:TIGR04521   81 RKKVGL-----V-FQFpehqlfeETVYKdiafgpkNLglseeeaeeRVKEALELVgLDEEYlerspfelsggqmrrvaia 154
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     594 -----DKEIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGSS--LFLKK 664
Cdd:TIGR04521  155 gvlamEPEVLILDEPTAGLDPKGRKEILDLFKRlhKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPreVFSDV 234
                          250
                   ....*....|
gi 6005701     665 KWGIGYHLSL 674
Cdd:TIGR04521  235 DELEKIGLDV 244
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
480-652 1.82e-24

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 102.94  E-value: 1.82e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTiYNNKLSEMADLENLSKL 559
Cdd:COG4133    3 LEAENLSCRRGERL----LFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVL-WNGEPIRDAREDYRRRL 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVqFDFLTVRENLRLFAKIKGILPQEVDKE--------------------------------------IFLLD 601
Cdd:COG4133   78 AYLGHADGL-KPELTVRENLRFWAALYGLRADREAIDealeavglagladlpvrqlsagqkrrvalarlllspapLWLLD 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 6005701   602 EPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQfmDEADILADRKVFLSQGK 652
Cdd:COG4133  157 EPFTALDAAGVALLAELIAAhLARGGAVLLTTH--QPLELAAARVLDLGDFK 206
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
1260-1436 2.15e-24

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 102.64  E-value: 2.15e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1260 RKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGD-----ALEFLGYcpqENALWPNL 1334
Cdd:PRK13539   12 RGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDpdvaeACHYLGH---RNAMKPAL 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1335 TVRQHLEVYAAVKGLRKGDAEVAItrlvDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQ 1414
Cdd:PRK13539   89 TVAENLEFWAAFLGGEELDIAAAL----EAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVA 164
                         170       180
                  ....*....|....*....|....
gi 6005701   1415 QMWQAIRAtfrNTERG--ALLTTH 1436
Cdd:PRK13539  165 LFAELIRA---HLAQGgiVIAATH 185
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
1267-1456 3.21e-24

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 108.57  E-value: 3.21e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----SGGGDALEfLG----YcpQENALWPNLTVR 1337
Cdd:COG1129   21 DGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGepvrfRSPRDAQA-AGiaiiH--QELNLVPNLSVA 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1338 Q--HLEVYAAVKGLRKGDAEVAITR-LVDALKLQDQLKSPVKTLSEGiKRKLcfVL---SILGNPSVVLLDEPSTGMDPE 1411
Cdd:COG1129   98 EniFLGREPRRGGLIDWRAMRRRAReLLARLGLDIDPDTPVGDLSVA-QQQL--VEiarALSRDARVLILDEPTASLTER 174
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 6005701  1412 GQQQMWQAIRaTFRntERGA--LLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:COG1129  175 EVERLFRIIR-RLK--AQGVaiIYISHRLDEVFEIADRVTVLRDGRL 218
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
499-597 3.70e-24

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 100.03  E-value: 3.70e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     499 LKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIyNNKLSEMADLENLSKLTGVCPQSNVQFDFLTVREN 578
Cdd:pfam00005    1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILL-DGQDLTDDERKSLRKEIGYVFQDPQLFPRLTVREN 79
                           90
                   ....*....|....*....
gi 6005701     579 LRLFAKIKGILPQEVDKEI 597
Cdd:pfam00005   80 LRLGLLLKGLSKREKDARA 98
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
480-657 5.08e-24

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 100.47  E-value: 5.08e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPDKIeaLKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADleNLSKL 559
Cdd:cd03247    1 LSINNVSFSYPEQEQQV--LKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEK--ALSSL 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDfLTVRENL----------RL-FAKikgILPQEVDkeIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVI 628
Cdd:cd03247   77 ISVLNQRPYLFD-TTLRNNLgrrfsggerqRLaLAR---ILLQDAP--IVLLDEPTVGLDPITERQLLSLIFEVLKDKTL 150
                        170       180
                 ....*....|....*....|....*....
gi 6005701   629 LFSTQFMDEADiLADRKVFLSQGKLKCAG 657
Cdd:cd03247  151 IWITHHLTGIE-HMDKILFLENGKIIMQG 178
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
479-691 1.34e-23

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 102.38  E-value: 1.34e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYKgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEmADLENLSK 558
Cdd:PRK13632    7 MIKVENVSFSYP--NSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISK-ENLKEIRK 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    559 LTGVCPQS-NVQFDFLTVR-------ENLRL-FAKIKGIL----------------PQE----------------VDKEI 597
Cdd:PRK13632   84 KIGIIFQNpDNQFIGATVEddiafglENKKVpPKKMKDIIddlakkvgmedyldkePQNlsggqkqrvaiasvlaLNPEI 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    598 FLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEAdILADRKVFLSQGKLKCAGS-SLFLKKKWGIG----- 669
Cdd:PRK13632  164 IIFDESTSMLDPKGKREIKKIMVDlrKTRKKTLISITHDMDEA-ILADKVIVFSEGKLIAQGKpKEILNNKEILEkakid 242
                         250       260
                  ....*....|....*....|....*.
gi 6005701    670 ----YHLSLQLNEICVEENITSLVKQ 691
Cdd:PRK13632  243 spfiYKLSKKLKGIDPTYNEEELIEQ 268
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
1258-1460 3.17e-23

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 99.64  E-value: 3.17e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1258 SKR-KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGD--------ALEFLGYcpqen 1328
Cdd:cd03301    7 TKRfGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDlppkdrdiAMVFQNY----- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1329 ALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGM 1408
Cdd:cd03301   82 ALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSNL 161
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 6005701  1409 DPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIG 1460
Cdd:cd03301  162 DAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
479-652 3.48e-23

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 102.99  E-value: 3.48e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENlsK 558
Cdd:PRK13536   41 AIDLAGVSKSYGDKA----VVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARARLAR--A 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    559 LTGVCPQ-SNVQFDFlTVRENLRLFAKIKGILPQEV----------------------------------------DKEI 597
Cdd:PRK13536  115 RIGVVPQfDNLDLEF-TVRENLLVFGRYFGMSTREIeavipsllefarleskadarvsdlsggmkrrltlaralinDPQL 193
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701    598 FLLDEPTAGLDPFSRHQVW----NLLKERKTdrvILFSTQFMDEADILADRKVFLSQGK 652
Cdd:PRK13536  194 LILDEPTTGLDPHARHLIWerlrSLLARGKT---ILLTTHFMEEAERLCDRLCVLEAGR 249
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
480-653 5.98e-23

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 97.11  E-value: 5.98e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGkpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIyNNKlsemadlenlskl 559
Cdd:cd03216    1 LELRGITKRFGG----VKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILV-DGK------------- 62
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 tgvcpqsnvQFDFLTVRENLRLfakikGI-----LP----QEV--------DKEIFLLDEPTAGLDPFSRHQVWNLLKER 622
Cdd:cd03216   63 ---------EVSFASPRDARRA-----GIamvyqLSvgerQMVeiaralarNARLLILDEPTAALTPAEVERLFKVIRRL 128
                        170       180       190
                 ....*....|....*....|....*....|..
gi 6005701   623 KTDRV-ILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:cd03216  129 RAQGVaVIFISHRLDEVFEIADRVTVLRDGRV 160
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
1267-1474 8.41e-23

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 98.95  E-value: 8.41e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSgggDALEF------LGYCPQENALWPNLTVRQHL 1340
Cdd:cd03299   16 KNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGK---DITNLppekrdISYVPQNYALFPHMTVYKNI 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1341 EVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAI 1420
Cdd:cd03299   93 AYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKLREEL 172
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701  1421 RATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQ----HLKSKFGKDYL 1474
Cdd:cd03299  173 KKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEevfkKPKNEFVAEFL 230
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
455-659 9.44e-23

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 104.21  E-value: 9.44e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   455 DEMDADPSFHDSFEQAPPEFQGKE-AIRIRNVTKEYKGK-PDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGL 532
Cdd:COG1123  235 QALAAVPRLGAARGRAAPAAAAAEpLLEVRNLSKRYPVRgKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGL 314
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   533 SVPTKGSVTIYNNKLSEM--ADLENLSKLTGVCPQS-NVQFD-FLTVRENLRLFAKIKGILPQE---------------- 592
Cdd:COG1123  315 LRPTSGSILFDGKDLTKLsrRSLRELRRRVQMVFQDpYSSLNpRMTVGDIIAEPLRLHGLLSRAerrervaellervglp 394
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   593 --------------------------VDKEIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADR 644
Cdd:COG1123  395 pdladryphelsggqrqrvaiaralaLEPKLLILDEPTSALDVSVQAQILNLLRDlqRELGLTYLFISHDLAVVRYIADR 474
                        250
                 ....*....|....*
gi 6005701   645 KVFLSQGKLKCAGSS 659
Cdd:COG1123  475 VAVMYDGRIVEDGPT 489
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
1245-1465 1.15e-22

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 98.42  E-value: 1.15e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1245 LRKEYAGKRKgcfskrkNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDAL-E 1319
Cdd:cd03258    7 VSKVFGDTGG-------KVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGtdltLLSGKELrK 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1320 F---LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNP 1396
Cdd:cd03258   80 ArrrIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNP 159
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701  1397 SVVLLDEPSTGMDPEGQQQMWQAIRATfrNTERG--ALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHL 1465
Cdd:cd03258  160 KVLLCDEATSALDPETTQSILALLRDI--NRELGltIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEV 228
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
479-653 1.28e-22

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 98.98  E-value: 1.28e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   479 AIRIRNVTKEYkgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEM--ADLENL 556
Cdd:COG3638    2 MLELRNLSKRY---PGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALrgRALRRL 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   557 SKLTGVCPQsnvQFDF---LTVREN---------------LRLFAK--------------IKGILPQEVDK--------- 595
Cdd:COG3638   79 RRRIGMIFQ---QFNLvprLSVLTNvlagrlgrtstwrslLGLFPPedreralealervgLADKAYQRADQlsggqqqrv 155
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   596 ----------EIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:COG3638  156 aiaralvqepKLILADEPVASLDPKTARQVMDLLRRiaREDGITVVVNLHQVDLARRYADRIIGLRDGRV 225
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
479-690 1.56e-22

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 100.55  E-value: 1.56e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   479 AIRIRNVTKEYK------G---------KPDK--IEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVT 541
Cdd:COG4586    1 IIEVENLSKTYRvyekepGlkgalkglfRREYreVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   542 I-----YNNKlsemadLENLSKLTGVCPQ-SNVQFDfLTVRENLRLFAKIKGILPQEVDK-------------------- 595
Cdd:COG4586   81 VlgyvpFKRR------KEFARRIGVVFGQrSQLWWD-LPAIDSFRLLKAIYRIPDAEYKKrldelvelldlgelldtpvr 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   596 --------------------EIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDeaDI--LADRKVFLSQG 651
Cdd:COG4586  154 qlslgqrmrcelaaallhrpKILFLDEPTIGLDVVSKEAIREFLKEynRERGTTILLTSHDMD--DIeaLCDRVIVIDHG 231
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 6005701   652 KLKCAGSSLFLKKKWGIGYHLSLQLNEICVEENITSLVK 690
Cdd:COG4586  232 RIIYDGSLEELKERFGPYKTIVLELAEPVPPLELPRGGE 270
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
1257-1460 1.61e-22

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 96.35  E-value: 1.61e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1257 FSKRKNKIAtRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGsgggdaleflgycpQENALWPNLTV 1336
Cdd:cd03214    7 VGYGGRTVL-DDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDG--------------KDLASLSPKEL 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1337 RQHLEVyaavkglrkgdaevaITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQM 1416
Cdd:cd03214   72 ARKIAY---------------VPQALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQIEL 136
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 6005701  1417 WQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIG 1460
Cdd:cd03214  137 LELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
480-653 2.28e-22

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 97.79  E-value: 2.28e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEY-----------------KGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI 542
Cdd:cd03267    1 IEVSNLSKSYrvyskepgligslkslfKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   543 YNNKLSEMADlENLSKLTGVCPQSN-VQFDfLTVRENLRLFAKIKGILPQE----VDK---------------------- 595
Cdd:cd03267   81 AGLVPWKRRK-KFLRRIGVVFGQKTqLWWD-LPVIDSFYLLAAIYDLPPARfkkrLDElselldleelldtpvrqlslgq 158
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701   596 --------------EIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:cd03267  159 rmraeiaaallhepEILFLDEPTIGLDVVAQENIRNFLKEynRERGTTVLLTSHYMKDIEALARRVLVIDKGRL 232
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
1267-1455 3.82e-22

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 97.46  E-value: 3.82e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LKGS--GGGDALE---FLGYCPQENALW--PNLTVRq 1338
Cdd:COG1119   20 DDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNDVrLFGErrGGEDVWElrkRIGLVSPALQLRfpRDETVL- 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1339 hlEV-----YAAVkGLRK--GDAEVAITR-LVDALKLQDQLKSPVKTLSEGIKRKlcfVL---SILGNPSVVLLDEPSTG 1407
Cdd:COG1119   99 --DVvlsgfFDSI-GLYRepTDEQRERAReLLELLGLAHLADRPFGTLSQGEQRR---VLiarALVKDPELLILDEPTAG 172
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 6005701  1408 MDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGR 1455
Cdd:COG1119  173 LDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGR 220
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
1256-1454 4.19e-22

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 96.17  E-value: 4.19e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1256 CFSKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS--GGGDALEFLGYCPQEnalwpn 1333
Cdd:cd03226    6 SFSYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKpiKAKERRKSIGYVMQD------ 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1334 ltVRQHL-------EVYAAVKGLRKGDAEVA-ITRLVDALKLQDQLksPvKTLSEGIKRKLCFVLSILGNPSVVLLDEPS 1405
Cdd:cd03226   80 --VDYQLftdsvreELLLGLKELDAGNEQAEtVLKDLDLYALKERH--P-LSLSGGQKQRLAIAAALLSGKDLLIFDEPT 154
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 6005701  1406 TGMDPEGQQQMWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSG 1454
Cdd:cd03226  155 SGLDYKNMERVGELIR-ELAAQGKAVIVITHDYEFLAKVCDRVLLLANG 202
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
1264-1456 7.40e-22

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 101.26  E-value: 7.40e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1264 IATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----SGGGDALEF-LGYCPQENALWPNLTVR 1337
Cdd:COG3845   19 VANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGkpvriRSPRDAIALgIGMVHQHFMLVPNLTVA 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1338 QHLeVYAAVKG----LRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQ 1413
Cdd:COG3845   99 ENI-VLGLEPTkggrLDRKAARARIRELSERYGLDVDPDAKVEDLSVGEQQRVEILKALYRGARILILDEPTAVLTPQEA 177
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 6005701  1414 QQMWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:COG3845  178 DELFEILRR-LAAEGKSIIFITHKLREVMAIADRVTVLRRGKV 219
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
1267-1456 8.99e-22

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 94.54  E-value: 8.99e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTA--GQVLLKGSGGgDALEF---LGYCPQENALWPNLTVRQHLE 1341
Cdd:cd03213   26 KNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLGvsGEVLINGRPL-DKRSFrkiIGYVPQDDILHPTLTVRETLM 104
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1342 VYAAVKGLrkgdaevaitrlvdalklqdqlkspvktlSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIR 1421
Cdd:cd03213  105 FAAKLRGL-----------------------------SGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLR 155
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 6005701  1422 AtFRNTERGALLTTHY-MAEAEAVCDRVAIMVSGRL 1456
Cdd:cd03213  156 R-LADTGRTIICSIHQpSSEIFELFDKLLLLSQGRV 190
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
1267-1466 9.95e-22

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 95.65  E-value: 9.95e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFL----GYCPQENALWPNLTVRQ 1338
Cdd:cd03261   17 KGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGedisGLSEAELYRLrrrmGMLFQSGALFDSLTVFE 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1339 HLEVYaavkgLR---KGDAEVaITRLVdALKLQ------DQLKSPVKtLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMD 1409
Cdd:cd03261   97 NVAFP-----LRehtRLSEEE-IREIV-LEKLEavglrgAEDLYPAE-LSGGMKKRVALARALALDPELLLYDEPTAGLD 168
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701  1410 PEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLK 1466
Cdd:cd03261  169 PIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELR 225
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
1262-1461 1.11e-21

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 95.77  E-value: 1.11e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1262 NKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsGGGDALEFLGYCPQEN------ALWPNLT 1335
Cdd:cd03300   12 GFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILL---DGKDITNLPPHKRPVNtvfqnyALFPHLT 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1336 VRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQ 1415
Cdd:cd03300   89 VFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGALDLKLRKD 168
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 6005701  1416 MWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:cd03300  169 MQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGT 214
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
480-653 1.27e-21

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 94.89  E-value: 1.27e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIynnklsemaDLENLSKL 559
Cdd:cd03259    1 LELKGLSKTYGSVR----ALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILI---------DGRDVTGV 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 ------TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDK-------------------------------------- 595
Cdd:cd03259   68 pperrnIGMVFQDYALFPHLTVAENIAFGLKLRGVPKAEIRArvrellelvglegllnryphelsggqqqrvalaralar 147
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701   596 --EIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:cd03259  148 epSLLLLDEPLSALDAKLREELREELKElqRELGITTIYVTHDQEEALALADRIAVMNEGRI 209
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
480-652 1.72e-21

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 94.81  E-value: 1.72e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYkgkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLSKL 559
Cdd:cd03224    1 LEVENLNAGY----GKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARAG 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFLTVRENLRL--FAKIKGILPQEVDK--EIF-----------------------------------LL 600
Cdd:cd03224   77 IGYVPEGRRIFPELTVEENLLLgaYARRRAKRKARLERvyELFprlkerrkqlagtlsggeqqmlaiaralmsrpkllLL 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 6005701   601 DEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGK 652
Cdd:cd03224  157 DEPSEGLAPKIVEEIFEAIRElRDEGVTILLVEQNARFALEIADRAYVLERGR 209
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
480-653 2.28e-21

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 94.49  E-value: 2.28e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMadLENLSKL 559
Cdd:cd03257    2 LEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKL--SRRLRKI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGvcpqSNVQFDF----------LTVRE------------------NLRLFAKIKGI---------LPQE---------- 592
Cdd:cd03257   80 RR----KEIQMVFqdpmsslnprMTIGEqiaeplrihgklskkearKEAVLLLLVGVglpeevlnrYPHElsggqrqrva 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701   593 ------VDKEIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:cd03257  156 iaralaLNPKLLIADEPTSALDVSVQAQILDLLKKlqEELGLTLLFITHDLGVVAKIADRVAVMYAGKI 224
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
480-653 2.59e-21

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 93.73  E-value: 2.59e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPDkieaLKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMaDLENLSKL 559
Cdd:COG4619    1 LELEGLSFRVGGKPI----LSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAM-PPPEWRRQ 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDfLTVRENL-----------------RLFAKI---KGILPQEVDK-------------------EIFLL 600
Cdd:COG4619   76 VAYVPQEPALWG-GTVRDNLpfpfqlrerkfdreralELLERLglpPDILDKPVERlsggerqrlaliralllqpDVLLL 154
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 6005701   601 DEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:COG4619  155 DEPTSALDPENTRRVEELLREylAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
479-653 3.17e-21

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 97.09  E-value: 3.17e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   479 AIRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIynnklsemaDLENLSK 558
Cdd:COG3842    5 ALELENVSKRYGDVT----ALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILL---------DGRDVTG 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   559 L------TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDK------------------------------------- 595
Cdd:COG3842   72 LppekrnVGMVFQDYALFPHLTVAENVAFGLRMRGVPKAEIRArvaellelvglegladryphqlsggqqqrvalarala 151
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701   596 ---EIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFST--QfmDEADILADRKVFLSQGKL 653
Cdd:COG3842  152 pepRVLLLDEPLSALDAKLREEMREELRRlqRELGITFIYVThdQ--EEALALADRIAVMNDGRI 214
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
1267-1462 3.40e-21

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 94.07  E-value: 3.40e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFLgycpQENALWPNLTVRQH--L 1340
Cdd:TIGR01184    2 KGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGkqitEPGPDRMVVF----QNYSLLPWLTVRENiaL 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1341 EVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDP-------EGQ 1413
Cdd:TIGR01184   78 AVDRVLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDAltrgnlqEEL 157
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 6005701    1414 QQMWQAIRATfrntergALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSI 1462
Cdd:TIGR01184  158 MQIWEEHRVT-------VLMVTHDVDEALLLSDRVVMLTNGPAANIGQI 199
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
480-653 3.72e-21

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 96.69  E-value: 3.72e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYN---NKLSEmADLENL 556
Cdd:COG1135    2 IELENLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGvdlTALSE-RELRAA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   557 SKLTGVCPQsnvQFDFL---TVRENLRLFAKIKGILPQEVDK-------------------------------------- 595
Cdd:COG1135   81 RRKIGMIFQ---HFNLLssrTVAENVALPLEIAGVPKAEIRKrvaellelvglsdkadaypsqlsggqkqrvgiaralan 157
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701   596 --EIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:COG1135  158 npKVLLCDEATSALDPETTRSILDLLKDinRELGLTIVLITHEMDVVRRICDRVAVLENGRI 219
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
479-652 5.53e-21

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 95.64  E-value: 5.53e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYKgkpDKIeALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLSk 558
Cdd:PRK13537    7 PIDFRNVEKRYG---DKL-VVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQR- 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    559 lTGVCPQ-SNVQFDFlTVRENLRLFAKIKGILPQEV----------------------------------------DKEI 597
Cdd:PRK13537   82 -VGVVPQfDNLDPDF-TVRENLLVFGRYFGLSAAAAralvppllefaklenkadakvgelsggmkrrltlaralvnDPDV 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701    598 FLLDEPTAGLDPFSRHQVW----NLLKERKTdrvILFSTQFMDEADILADRKVFLSQGK 652
Cdd:PRK13537  160 LVLDEPTTGLDPQARHLMWerlrSLLARGKT---ILLTTHFMEEAERLCDRLCVIEEGR 215
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
479-658 6.21e-21

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 93.62  E-value: 6.21e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   479 AIRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNnklsemADLENLSK 558
Cdd:COG1121    6 AIELENLTVSYGGRP----VLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFG------KPPRRARR 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   559 LTGVCPQ-SNVQFDF-LTVRE--------NLRLFAKIKGILPQEVDK--------------------------------- 595
Cdd:COG1121   76 RIGYVPQrAEVDWDFpITVRDvvlmgrygRRGLFRRPSRADREAVDEalervgledladrpigelsggqqqrvllarala 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701   596 ---EIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKLkCAGS 658
Cdd:COG1121  156 qdpDLLLLDEPFAGVDAATEEALYELLRElRREGKTILVVTHDLGAVREYFDRVLLLNRGLV-AHGP 221
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
1263-1478 7.36e-21

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 94.03  E-value: 7.36e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1263 KIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSgggDALEflgycpqENALWpnlTVRQHLE- 1341
Cdd:TIGR04520   15 KPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGL---DTLD-------EENLW---EIRKKVGm 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1342 ---------VYAAVK-----GL--RKGDAEVAITRLVDALK---LQDQLKSPVKTLSEGIKRKLCfVLSILG-NPSVVLL 1401
Cdd:TIGR04520   82 vfqnpdnqfVGATVEddvafGLenLGVPREEMRKRVDEALKlvgMEDFRDREPHLLSGGQKQRVA-IAGVLAmRPDIIIL 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1402 DEPsTGM-DPEGQQQMWQAIRATfrNTERGA--LLTTHYMAEAeAVCDRVAIMVSGRLRCIGSIQHLKSKfgKDYLLEMK 1478
Cdd:TIGR04520  161 DEA-TSMlDPKGRKEVLETIRKL--NKEEGItvISITHDMEEA-VLADRVIVMNKGKIVAEGTPREIFSQ--VELLKEIG 234
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
480-657 9.19e-21

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 92.34  E-value: 9.19e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKpdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMAdlenlSKL 559
Cdd:cd03269    1 LEVENVTKRFGRV----TALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAA-----RNR 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEV----------------------------------------DKEIFL 599
Cdd:cd03269   72 IGYLPEERGLYPKMKVIDQLVYLAQLKGLKKEEArrridewlerlelseyankrveelskgnqqkvqfiaavihDPELLI 151
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701   600 LDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAG 657
Cdd:cd03269  152 LDEPFSGLDPVNVELLKDVIRElARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
509-657 1.15e-20

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 92.17  E-value: 1.15e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   509 GQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNnklSEMADLENLSKLTGVCPQSNVQFDFLTVREN--------LR 580
Cdd:cd03298   24 GEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLING---VDVTAAPPADRPVSMLFQENNLFAHLTVEQNvglglspgLK 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   581 LFA----KIKGI------------LPQEV----------------DKEIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDR 626
Cdd:cd03298  101 LTAedrqAIEVAlarvglaglekrLPGELsggerqrvalarvlvrDKPVLLLDEPFAALDPALRAEMLDLVLDlhAETKM 180
                        170       180       190
                 ....*....|....*....|....*....|.
gi 6005701   627 VILFSTQFMDEADILADRKVFLSQGKLKCAG 657
Cdd:cd03298  181 TVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
1267-1475 1.46e-20

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 98.37  E-value: 1.46e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsGGGDALEF--------LGYCPQENALWP-----N 1333
Cdd:COG2274  492 DNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILI---DGIDLRQIdpaslrrqIGVVLQDVFLFSgtireN 568
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1334 LTVrqhlevyaavkglrkGDAEVAITRLVDALK----------LQDQLKSPV----KTLSEGIKRKLCFVLSILGNPSVV 1399
Cdd:COG2274  569 ITL---------------GDPDATDEEIIEAARlaglhdfieaLPMGYDTVVgeggSNLSGGQRQRLAIARALLRNPRIL 633
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701  1400 LLDEPSTGMDPEGQQQMWQAIRATFRNteRGALLTTHYMAEAEAvCDRVAIMVSGRLRCIGSIQHLKSKFGKDYLL 1475
Cdd:COG2274  634 ILDEATSALDAETEAIILENLRRLLKG--RTVIIIAHRLSTIRL-ADRIIVLDKGRIVEDGTHEELLARKGLYAEL 706
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
480-653 1.57e-20

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 91.83  E-value: 1.57e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEY------------------KGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVT 541
Cdd:cd03220    1 IELENVSKSYptykggssslkklgilgrKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   542 IyNNKLSEMADLEnlsklTGVCPQsnvqfdfLTVRENLRLFAKIKGILPQEVDK-------------------------- 595
Cdd:cd03220   81 V-RGRVSSLLGLG-----GGFNPE-------LTGRENIYLNGRLLGLSRKEIDEkideiiefselgdfidlpvktyssgm 147
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6005701   596 --------------EIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:cd03220  148 karlafaiatalepDILLIDEVLAVGDAAFQEKCQRRLRElLKQGKTVILVSHDPSSIKRLCDRALVLEKGKI 220
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
478-658 2.21e-20

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 92.07  E-value: 2.21e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   478 EAIRIRNVTKEY------------------KGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGS 539
Cdd:COG1134    3 SMIEVENVSKSYrlyhepsrslkelllrrrRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   540 VTIyNNKLSEMADLEnlsklTGVCPQsnvqfdfLTVRENLRLFAKIKGILPQEVDK------------------------ 595
Cdd:COG1134   83 VEV-NGRVSALLELG-----AGFHPE-------LTGRENIYLNGRLLGLSRKEIDEkfdeivefaelgdfidqpvktyss 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   596 ----------------EIFLLDEPTAGLDPFSRHQVWNLLKERKTD-RVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:COG1134  150 gmrarlafavatavdpDILLVDEVLAVGDAAFQKKCLARIRELRESgRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGD 229
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
479-653 2.80e-20

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 94.37  E-value: 2.80e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   479 AIRIRNVTKEYkgkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIyNNKLseMADLEnlsk 558
Cdd:COG3839    3 SLELENVSKSY----GGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILI-GGRD--VTDLP---- 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   559 ltgvcP---------QSNVQFDFLTVRENLrLFA-KIKGILPQEVDK--------------------------------- 595
Cdd:COG3839   72 -----PkdrniamvfQSYALYPHMTVYENI-AFPlKLRKVPKAEIDRrvreaaellgledlldrkpkqlsggqrqrvalg 145
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701   596 -------EIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:COG3839  146 ralvrepKVFLLDEPLSNLDAKLRVEMRAEIKRlhRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRI 212
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
1239-1461 2.82e-20

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 91.88  E-value: 2.82e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1239 VIIASCLRKEYAGKRkgcfskrknkiATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSG----- 1313
Cdd:PRK10895    3 TLTAKNLAKAYKGRR-----------VVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDisllp 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1314 -GGDALEFLGYCPQENALWPNLTVRQHL-EVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLS 1391
Cdd:PRK10895   72 lHARARRGIGYLPQEASIFRRLSVYDNLmAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARA 151
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1392 ILGNPSVVLLDEPSTGMDPEGQQQMWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:PRK10895  152 LAANPKFILLDEPFAGVDPISVIDIKRIIEH-LRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGT 220
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
480-653 2.82e-20

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 91.98  E-value: 2.82e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMaDLENLSKL 559
Cdd:cd03295    1 IEFENVTKRYGGGK---KAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQ-DPVELRRK 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEV------------------------------------------DKEI 597
Cdd:cd03295   77 IGYVIQQIGLFPHMTVEENIALVPKLLKWPKEKIreradellalvgldpaefadryphelsggqqqrvgvaralaaDPPL 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701   598 FLLDEPTAGLDPFSRHQVWNLLK--ERKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:cd03295  157 LLMDEPFGALDPITRDQLQEEFKrlQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEI 214
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
1265-1468 2.90e-20

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 96.75  E-value: 2.90e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsGGGDALEF--------LGYCPQeNALWPNLTV 1336
Cdd:COG4988  352 ALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILI---NGVDLSDLdpaswrrqIAWVPQ-NPYLFAGTI 427
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1337 RQHL----------EVYAAVKglrkgdaEVAITRLVDAlkLQDQLKSPV----KTLSEGIKRKLCFVLSILGNPSVVLLD 1402
Cdd:COG4988  428 RENLrlgrpdasdeELEAALE-------AAGLDEFVAA--LPDGLDTPLgeggRGLSGGQAQRLALARALLRDAPLLLLD 498
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701  1403 EPSTGMDPEGQQQMWQAIRATFRNteRGALLTTHYMAEAEAvCDRVAIMVSGRLRCIGSIQHLKSK 1468
Cdd:COG4988  499 EPTAHLDAETEAEILQALRRLAKG--RTVILITHRLALLAQ-ADRILVLDDGRIVEQGTHEELLAK 561
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
1236-1460 3.16e-20

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 96.41  E-value: 3.16e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1236 EKPVIIASCLRKEYAGKRKGCFSkrknkiATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLK----- 1310
Cdd:TIGR03269  276 GEPIIKVRNVSKRYISVDRGVVK------AVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRvgdew 349
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1311 -------GSGGGDALEFLGYCPQENALWPNLTVrqhLEVYAAVKGLRKGDaEVAITRLVDALKL----QDQLKSPVK--- 1376
Cdd:TIGR03269  350 vdmtkpgPDGRGRAKRYIGILHQEYDLYPHRTV---LDNLTEAIGLELPD-ELARMKAVITLKMvgfdEEKAEEILDkyp 425
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1377 -TLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGR 1455
Cdd:TIGR03269  426 dELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGK 505

                   ....*
gi 6005701    1456 LRCIG 1460
Cdd:TIGR03269  506 IVKIG 510
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
1251-1456 4.12e-20

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 90.79  E-value: 4.12e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1251 GKRKGCF-SKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITG---DTKPTAGQVLLKGSgGGDALEFL---GY 1323
Cdd:cd03234    7 WDVGLKAkNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGrveGGGTTSGQILFNGQ-PRKPDQFQkcvAY 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1324 CPQENALWPNLTVRQHLeVYAAVKGLRKGDAEVAITRLVDALKLQD----QLKSP-VKTLSEGIKRKLCFVLSILGNPSV 1398
Cdd:cd03234   86 VRQDDILLPGLTVRETL-TYTAILRLPRKSSDAIRKKRVEDVLLRDlaltRIGGNlVKGISGGERRRVSIAVQLLWDPKV 164
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701  1399 VLLDEPSTGMDPEGQQQMWQAIRATFRnTERGALLTTHY-MAEAEAVCDRVAIMVSGRL 1456
Cdd:cd03234  165 LILDEPTSGLDSFTALNLVSTLSQLAR-RNRIVILTIHQpRSDLFRLFDRILLLSSGEI 222
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
1265-1456 4.38e-20

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 90.73  E-value: 4.38e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsGGGDALEF--------LGYCPQENALWpNLTV 1336
Cdd:cd03245   19 ALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLL---DGTDIRQLdpadlrrnIGYVPQDVTLF-YGTL 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1337 RQHLEVyaavkglrkGDAEVAITRLVDALKLQ--DQL--KSPV----------KTLSEGIKRKLCFVLSILGNPSVVLLD 1402
Cdd:cd03245   95 RDNITL---------GAPLADDERILRAAELAgvTDFvnKHPNgldlqigergRGLSGGQRQAVALARALLNDPPILLLD 165
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 6005701  1403 EPSTGMDPEGQQQMWQAIRATFRntERGALLTTHYMAeAEAVCDRVAIMVSGRL 1456
Cdd:cd03245  166 EPTSAMDMNSEERLKERLRQLLG--DKTLIIITHRPS-LLDLVDRIIVMDSGRI 216
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
479-658 4.70e-20

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 92.48  E-value: 4.70e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   479 AIRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIyNNKLSEMADLENLSK 558
Cdd:COG4152    1 MLELKGLTKRFGDKT----AVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLW-DGEPLDPEDRRRIGY 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   559 L---TGVCPQsnvqfdfLTVRENLRLFAKIKGILPQEVDKEI-------------------------------------- 597
Cdd:COG4152   76 LpeeRGLYPK-------MKVGEQLVYLARLKGLSKAEAKRRAdewlerlglgdrankkveelskgnqqkvqliaallhdp 148
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701   598 -FL-LDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:COG4152  149 eLLiLDEPFSGLDPVNVELLKDVIRElAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGS 212
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
480-621 6.17e-20

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 90.11  E-value: 6.17e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYkgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEM--ADLENLS 557
Cdd:COG2884    2 IRFENVSKRY---PGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLkrREIPYLR 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   558 KLTGVCPQsnvqfDF-----LTVRENLRLFAKIKGILPQEVDK------------------------------------- 595
Cdd:COG2884   79 RRIGVVFQ-----DFrllpdRTVYENVALPLRVTGKSRKEIRRrvrevldlvglsdkakalphelsggeqqrvaiaralv 153
                        170       180
                 ....*....|....*....|....*....
gi 6005701   596 ---EIFLLDEPTAGLDPFSRHQVWNLLKE 621
Cdd:COG2884  154 nrpELLLADEPTGNLDPETSWEIMELLEE 182
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
478-658 6.31e-20

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 91.37  E-value: 6.31e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    478 EAIRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLEnLS 557
Cdd:PRK13548    1 AMLEARNLSVRLGGRT----LLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAE-LA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    558 KLTGVCPQ-SNVQFDFlTVRENLRLFAKIKGILPQEVD------------------------------------------ 594
Cdd:PRK13548   76 RRRAVLPQhSSLSFPF-TVEEVVAMGRAPHGLSRAEDDalvaaalaqvdlahlagrdypqlsggeqqrvqlarvlaqlwe 154
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701    595 ----KEIFLLDEPTAGLDPFSRHQVWNLLKERKTDR-----VIL----FSTQFmdeadilADRKVFLSQGKLKCAGS 658
Cdd:PRK13548  155 pdgpPRWLLLDEPTSALDLAHQHHVLRLARQLAHERglaviVVLhdlnLAARY-------ADRIVLLHQGRLVADGT 224
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
480-652 8.05e-20

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 90.32  E-value: 8.05e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYkgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEM--ADLENLS 557
Cdd:cd03256    1 IEVENLSKTY---PNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLkgKALRQLR 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   558 KLTGVCPQS-----------NVQFDFL----TVRENLRLFAKIK-----------GILP---QEVDK------------- 595
Cdd:cd03256   78 RQIGMIFQQfnlierlsvleNVLSGRLgrrsTWRSLFGLFPKEEkqralaalervGLLDkayQRADQlsggqqqrvaiar 157
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701   596 ------EIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGK 652
Cdd:cd03256  158 almqqpKLILADEPVASLDPASSRQVMDLLKRinREEGITVIVSLHQVDLAREYADRIVGLKDGR 222
cbiO PRK13649
energy-coupling factor transporter ATPase;
479-658 8.99e-20

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 91.34  E-value: 8.99e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYK-GKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKL---SEMADLE 554
Cdd:PRK13649    2 GINLQNVSYTYQaGTPFEGRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLItstSKNKDIK 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    555 NLSKLTGVC---PQSNVqFDfLTV----------------------RENLR-------LFAK--------------IKGI 588
Cdd:PRK13649   82 QIRKKVGLVfqfPESQL-FE-ETVlkdvafgpqnfgvsqeeaealaREKLAlvgisesLFEKnpfelsggqmrrvaIAGI 159
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701    589 LPQEVDkeIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:PRK13649  160 LAMEPK--ILVLDEPTAGLDPKGRKELMTLFKKlHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGK 228
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
481-654 1.04e-19

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 89.24  E-value: 1.04e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   481 RIRNVTKEYKgkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMAdlenLSKLT 560
Cdd:cd03226    1 RIENISFSYK---KGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAKE----RRKSI 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   561 GVCPQ-SNVQFDFLTVRENLRLFAKIKGILPQEV------------------------------------DKEIFLLDEP 603
Cdd:cd03226   74 GYVMQdVDYQLFTDSVREELLLGLKELDAGNEQAetvlkdldlyalkerhplslsggqkqrlaiaaallsGKDLLIFDEP 153
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 6005701   604 TAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKLK 654
Cdd:cd03226  154 TSGLDYKNMERVGELIRElAAQGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
1236-1460 1.82e-19

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 90.01  E-value: 1.82e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1236 EKPVIIASCLRKEYAGKRKGCFskrknkIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsGGG 1315
Cdd:cd03294   16 KAFKLLAKGKSKEEILKKTGQT------VGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLI---DGQ 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1316 DALEF------------LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIK 1383
Cdd:cd03294   87 DIAAMsrkelrelrrkkISMVFQSFALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQ 166
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701  1384 RKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIG 1460
Cdd:cd03294  167 QRVGLARALAVDPDILLMDEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVG 243
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
457-653 1.94e-19

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 94.46  E-value: 1.94e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   457 MDADPSFHDSfEQAPPEFQGKEAIRIRNVTKEYkgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPT 536
Cdd:COG1132  318 LDEPPEIPDP-PGAVPLPPVRGEIEFENVSFSY---PGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPT 393
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   537 KGSVTIYNNKLSEMaDLENLSKLTGVCPQSNVQFDfLTVRENLRLF------------AKIKGI------LPQ----EV- 593
Cdd:COG1132  394 SGRILIDGVDIRDL-TLESLRRQIGVVPQDTFLFS-GTIRENIRYGrpdatdeeveeaAKAAQAhefieaLPDgydtVVg 471
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   594 ----------------------DKEIFLLDEPTAGLDPFSRHQVWNLLKERKTDR-VIL----FSTqfmdeadIL-ADRK 645
Cdd:COG1132  472 ergvnlsggqrqriaiarallkDPPILILDEATSALDTETEALIQEALERLMKGRtTIViahrLST-------IRnADRI 544

                 ....*...
gi 6005701   646 VFLSQGKL 653
Cdd:COG1132  545 LVLDDGRI 552
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
1265-1461 2.55e-19

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 88.94  E-value: 2.55e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsGGGDALEF------LGYCPQENALWPNLTVRQ 1338
Cdd:cd03296   17 ALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILF---GGEDATDVpvqernVGFVFQHYALFRHMTVFD 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1339 HLEVYAAVKGLRKGDAEVAITRLVDAL-------KLQDQLKSpvkTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPE 1411
Cdd:cd03296   94 NVAFGLRVKPRSERPPEAEIRAKVHELlklvqldWLADRYPA---QLSGGQRQRVALARALAVEPKVLLLDEPFGALDAK 170
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 6005701  1412 GQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:cd03296  171 VRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGT 220
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
1267-1455 2.80e-19

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 86.67  E-value: 2.80e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsGGGDALEF--------LGYCPQENALWpNLTVRQ 1338
Cdd:cd03228   19 KDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILI---DGVDLRDLdleslrknIAYVPQDPFLF-SGTIRE 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1339 HLevyaavkglrkgdaevaitrlvdalklqdqlkspvktLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQ 1418
Cdd:cd03228   95 NI-------------------------------------LSGGQRQRIAIARALLRDPPILILDEATSALDPETEALILE 137
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 6005701  1419 AIRATFRNteRGALLTTHYMAEAEAvCDRVAIMVSGR 1455
Cdd:cd03228  138 ALRALAKG--KTVIVIAHRLSTIRD-ADRIIVLDDGR 171
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
480-674 4.14e-19

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 89.69  E-value: 4.14e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYKGK-PDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLS---EMADLEN 555
Cdd:PRK13634    3 ITFQKVEHRYQYKtPFERRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITagkKNKKLKP 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    556 LSKLTGVCPQ--------SNVQFD-------FLTVRENLRLFAK--IKGI-LPQEV------------------------ 593
Cdd:PRK13634   83 LRKKVGIVFQfpehqlfeETVEKDicfgpmnFGVSEEDAKQKARemIELVgLPEELlarspfelsggqmrrvaiagvlam 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    594 DKEIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS--SLFLKKKWGIG 669
Cdd:PRK13634  163 EPEVLVLDEPTAGLDPKGRKEMMEMFYKlhKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTprEIFADPDELEA 242

                  ....*
gi 6005701    670 YHLSL 674
Cdd:PRK13634  243 IGLDL 247
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
1267-1456 7.23e-19

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 86.81  E-value: 7.23e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG---SGGGDALEFL----GYCPQENALWPNLTVRQH 1339
Cdd:cd03262   17 KGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGlklTDDKKNINELrqkvGMVFQQFNLFPHLTVLEN 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1340 L-EVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEG------IKRKLCFvlsilgNPSVVLLDEPSTGMDPEG 1412
Cdd:cd03262   97 ItLAPIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGqqqrvaIARALAM------NPKVMLFDEPTSALDPEL 170
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 6005701  1413 QQQMWQAIRatfRNTERGA--LLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:cd03262  171 VGEVLDVMK---DLAEEGMtmVVVTHEMGFAREVADRVIFMDDGRI 213
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
480-653 7.57e-19

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 88.47  E-value: 7.57e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKP-----------DKIE---------ALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGS 539
Cdd:cd03294    1 IKIKGLYKIFGKNPqkafkllakgkSKEEilkktgqtvGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   540 VTIYNNKLSEM--ADLENL-SKLTGVCPQSNVQFDFLTVRENLRLFAKIKGILPQE------------------------ 592
Cdd:cd03294   81 VLIDGQDIAAMsrKELRELrRKKISMVFQSFALLPHRTVLENVAFGLEVQGVPRAEreeraaealelvglegwehkypde 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701   593 ----------------VDKEIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:cd03294  161 lsggmqqrvglaralaVDPDILLMDEAFSALDPLIRREMQDELLRlqAELQKTIVFITHDLDEALRLGDRIAIMKDGRL 239
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
1265-1490 9.44e-19

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 89.79  E-value: 9.44e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSiKVITGDTKPTAGQvllkgsgggDALEFLGYCPQENALW------------- 1331
Cdd:NF000106   28 AVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGR---------RPWRF*TWCANRRALRrtig*hrpvr*gr 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1332 -PNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDP 1410
Cdd:NF000106   98 rESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDP 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1411 EGQQQMWQAIRATFRNTERgALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFGKDYLlemkvknlaQVEPLHA 1490
Cdd:NF000106  178 RTRNEVWDEVRSMVRDGAT-VLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVGGRTL---------QIRPAHA 247
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
480-653 1.00e-18

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 86.43  E-value: 1.00e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKpdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLS-EMADLENLSK 558
Cdd:cd03262    1 IEIKNLHKSFGDF----HVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTdDKKNINELRQ 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   559 LTGVCPQSNVQFDFLTVRENLRLfAKIK--------------------GILPQE----------------------VDKE 596
Cdd:cd03262   77 KVGMVFQQFNLFPHLTVLENITL-APIKvkgmskaeaeeralellekvGLADKAdaypaqlsggqqqrvaiaralaMNPK 155
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701   597 IFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:cd03262  156 VMLFDEPTSALDPELVGEVLDVMKDlAEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
480-652 1.07e-18

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 86.73  E-value: 1.07e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkiealkdLVFD--IYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIyNNklsemadlENLS 557
Cdd:COG3840    2 LRLDDLTYRYGDFP--------LRFDltIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILW-NG--------QDLT 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   558 KLTgvcP---------QSNVQFDFLTVREN--------LRLFA----KIKGIL------------PQEV----------- 593
Cdd:COG3840   65 ALP---PaerpvsmlfQENNLFPHLTVAQNiglglrpgLKLTAeqraQVEQALervglaglldrlPGQLsggqrqrvala 141
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701   594 -----DKEIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGK 652
Cdd:COG3840  142 rclvrKRPILLLDEPFSALDPALRQEMLDLVDElcRERGLTVLMVTHDPEDAARIADRVLLVADGR 207
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
1267-1461 1.22e-18

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 89.36  E-value: 1.22e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsGGGDALEF------LGYCPQENALWPNLTVRQHL 1340
Cdd:COG3839   20 KDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILI---GGRDVTDLppkdrnIAMVFQSYALYPHMTVYENI 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1341 EVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEG------IKRklcfvlSILGNPSVVLLDEPSTGMDPEGQQ 1414
Cdd:COG3839   97 AFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGqrqrvaLGR------ALVREPKVFLLDEPLSNLDAKLRV 170
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 6005701  1415 QMWQAIRATFRntERGA--LLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:COG3839  171 EMRAEIKRLHR--RLGTttIYVTHDQVEAMTLADRIAVMNDGRIQQVGT 217
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
1263-1456 1.86e-18

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 84.79  E-value: 1.86e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1263 KIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----SGGGDALEF-LGYCP---QENALWPN 1333
Cdd:cd03215   13 KGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGkpvtrRSPRDAIRAgIAYVPedrKREGLVLD 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1334 LTVRQHLevyaavkglrkgdaevAITRLvdalklqdqlkspvktLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQ 1413
Cdd:cd03215   93 LSVAENI----------------ALSSL----------------LSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAK 140
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 6005701  1414 QQMWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:cd03215  141 AEIYRLIRE-LADAGKAVLLISSELDELLGLCDRILVMYEGRI 182
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
1237-1404 2.19e-18

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 90.51  E-value: 2.19e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1237 KPVIIASCLRKEYAGKrkgcfskrknKIAtRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsggGD 1316
Cdd:COG0488  313 KKVLELEGLSKSYGDK----------TLL-DDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-----GE 376
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1317 ALEfLGYCPQENA-LWPNLTVRQHLevyaavKGLRKGDAEVAITRLVDALKL-QDQLKSPVKTLSEGIKRKLCFVLSILG 1394
Cdd:COG0488  377 TVK-IGYFDQHQEeLDPDKTVLDEL------RDGAPGGTEQEVRGYLGRFLFsGDDAFKPVGVLSGGEKARLALAKLLLS 449
                        170
                 ....*....|
gi 6005701  1395 NPSVVLLDEP 1404
Cdd:COG0488  450 PPNVLLLDEP 459
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
483-620 2.24e-18

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 84.99  E-value: 2.24e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   483 RNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSG--LSVPTKGSVTIYNNKLSemadlENLSKLT 560
Cdd:cd03232    7 KNLNYTVPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGrkTAGVITGEILINGRPLD-----KNFQRST 81
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   561 GVCPQSNVQFDFLTVRENLRLFAKIKGILPQE-----------VDKEIFLLDEPTAGLDPFSRHQVWNLLK 620
Cdd:cd03232   82 GYVEQQDVHSPNLTVREALRFSALLRGLSVEQrkrltigvelaAKPSILFLDEPTSGLDSQAAYNIVRFLK 152
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
481-659 2.42e-18

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 85.80  E-value: 2.42e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   481 RIRNVTKEYkgkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIynnklsemaDLENLSKLT 560
Cdd:COG0410    5 EVENLHAGY----GGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRF---------DGEDITGLP 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   561 ---------GVCPQS-NVqFDFLTVRENLRLFA---KIKGILPQEVDK--EIF--------------------------- 598
Cdd:COG0410   72 phriarlgiGYVPEGrRI-FPSLTVEENLLLGAyarRDRAEVRADLERvyELFprlkerrrqragtlsggeqqmlaigra 150
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   599 --------LLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGSS 659
Cdd:COG0410  151 lmsrpkllLLDEPSLGLAPLIVEEIFEIIRRlNREGVTILLVEQNARFALEIADRAYVLERGRIVLEGTA 220
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
1259-1463 2.80e-18

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 86.36  E-value: 2.80e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1259 KRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGD--ALEF---LGYCPQENALWPN 1333
Cdd:PRK13548   11 RLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADwsPAELarrRAVLPQHSSLSFP 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1334 LTVRQHLEVYAAVKGLRKGDAEVAIT---RLVDALKLQDqlkSPVKTLSEGIK------RKLCFVLSILGNPSVVLLDEP 1404
Cdd:PRK13548   91 FTVEEVVAMGRAPHGLSRAEDDALVAaalAQVDLAHLAG---RDYPQLSGGEQqrvqlaRVLAQLWEPDGPPRWLLLDEP 167
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701   1405 STGMDPEGQQQMWQAIRAtfRNTERGA--------L-LTTHYmaeaeavCDRVAIMVSGRLRCIGSIQ 1463
Cdd:PRK13548  168 TSALDLAHQHHVLRLARQ--LAHERGLavivvlhdLnLAARY-------ADRIVLLHQGRLVADGTPA 226
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
480-653 4.00e-18

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 84.61  E-value: 4.00e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNklsEMADLENLSKL 559
Cdd:cd03301    1 VELENVTKRFGNVT----ALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGR---DVTDLPPKDRD 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDK----------------------------------------EIFL 599
Cdd:cd03301   74 IAMVFQNYALYPHMTVYDNIAFGLKLRKVPKDEIDErvrevaellqiehlldrkpkqlsggqrqrvalgraivrepKVFL 153
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701   600 LDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:cd03301  154 MDEPLSNLDAKLRVQMRAELKRlqQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQI 209
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
480-658 4.17e-18

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 85.94  E-value: 4.17e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLEnLSKL 559
Cdd:COG4559    2 LEAENLSVRLGGRT----LLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWE-LARR 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQ-SNVQFDFlTVRENLRLfAKIKGILPQEVDKEI----------------------------------------- 597
Cdd:COG4559   77 RAVLPQhSSLAFPF-TVEEVVAL-GRAPHGSSAAQDRQIvrealalvglahlagrsyqtlsggeqqrvqlarvlaqlwep 154
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701   598 -------FLLDEPTAGLDPFSRHQVWNLLKERkTDR-----VIL----FSTQFmdeadilADRKVFLSQGKLKCAGS 658
Cdd:COG4559  155 vdggprwLFLDEPTSALDLAHQHAVLRLARQL-ARRgggvvAVLhdlnLAAQY-------ADRILLLHQGRLVAQGT 223
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
1267-1456 5.91e-18

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 83.03  E-value: 5.91e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDAL-EFLGYCPQENALWPNlTVRQHLe 1341
Cdd:cd03246   19 RNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGadisQWDPNELgDHVGYLPQDDELFSG-SIAENI- 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1342 vyaavkglrkgdaevaitrlvdalklqdqlkspvktLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIR 1421
Cdd:cd03246   97 ------------------------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQAIA 140
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 6005701  1422 ATfrnTERGA--LLTTHYMaEAEAVCDRVAIMVSGRL 1456
Cdd:cd03246  141 AL---KAAGAtrIVIAHRP-ETLASADRILVLEDGRV 173
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
479-658 6.58e-18

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 89.19  E-value: 6.58e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   479 AIRIRNVTKEYKGkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPT---KGSVTIYNNKLSEMaDLEN 555
Cdd:COG1123    4 LLEVRDLSVRYPG--GDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLEL-SEAL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   556 LSKLTGVCPQS-NVQFDFLTVRENLRLFAKIKGILPQEVDK--------------------------------------- 595
Cdd:COG1123   81 RGRRIGMVFQDpMTQLNPVTVGDQIAEALENLGLSRAEARArvlelleavglerrldryphqlsggqrqrvaiamalald 160
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701   596 -EIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:COG1123  161 pDLLIADEPTTALDVTTQAEILDLLRElqRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGP 226
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
1265-1474 6.73e-18

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 87.58  E-value: 6.73e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGggdalefLGYCP----------QENALWPNL 1334
Cdd:PRK11607   34 AVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVD-------LSHVPpyqrpinmmfQSYALFPHM 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1335 TVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQ 1414
Cdd:PRK11607  107 TVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRD 186
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701   1415 QMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGS----IQHLKSKFGKDYL 1474
Cdd:PRK11607  187 RMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEpeeiYEHPTTRYSAEFI 250
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
479-653 1.15e-17

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 83.41  E-value: 1.15e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   479 AIRIRNVTKEYKgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMaDLENLSK 558
Cdd:cd03245    2 RIEFRNVSFSYP--NQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQL-DPADLRR 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   559 LTGVCPQSNVQFdFLTVRENLRLF------------AKIKGILP-------------------------QEV-------- 593
Cdd:cd03245   79 NIGYVPQDVTLF-YGTLRDNITLGapladderilraAELAGVTDfvnkhpngldlqigergrglsggqrQAValaralln 157
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   594 DKEIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADiLADRKVFLSQGKL 653
Cdd:cd03245  158 DPPILLLDEPTSAMDMNSEERLKERLRQLLGDKTLIIITHRPSLLD-LVDRIIVMDSGRI 216
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
1258-1411 1.35e-17

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 83.56  E-value: 1.35e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1258 SKR--KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFL----GYCPQE 1327
Cdd:COG2884    8 SKRypGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGqdlsRLKRREIPYLrrriGVVFQD 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1328 NALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTG 1407
Cdd:COG2884   88 FRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLADEPTGN 167

                 ....
gi 6005701  1408 MDPE 1411
Cdd:COG2884  168 LDPE 171
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
481-657 1.70e-17

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 82.97  E-value: 1.70e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   481 RIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMadlenlSKLT 560
Cdd:cd03235    1 EVEDLTVSYGGHP----VLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKE------RKRI 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   561 GVCPQS-NVQFDF-LTVRE--NLRLFAKIKGILP----------------------------------QEV--------D 594
Cdd:cd03235   71 GYVPQRrSIDRDFpISVRDvvLMGLYGHKGLFRRlskadkakvdealervglseladrqigelsggqqQRVllaralvqD 150
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701   595 KEIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRkVFLSQGKLKCAG 657
Cdd:cd03235  151 PDLLLLDEPFAGVDPKTQEDIYELLRElRREGMTILVVTHDLGLVLEYFDR-VLLLNRTVVASG 213
cbiO PRK13646
energy-coupling factor transporter ATPase;
480-674 1.74e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 84.83  E-value: 1.74e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEY-KGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIynNKLSEMAD-----L 553
Cdd:PRK13646    3 IRFDNVSYTYqKGTPYEHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTV--DDITITHKtkdkyI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    554 ENLSKLTGVC---PQS----------------NVQFDFLTVRE--------------------------NLRLFAkIKGI 588
Cdd:PRK13646   81 RPVRKRIGMVfqfPESqlfedtvereiifgpkNFKMNLDEVKNyahrllmdlgfsrdvmsqspfqmsggQMRKIA-IVSI 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    589 LPqeVDKEIFLLDEPTAGLDPFSRHQVWNLLKERKTD--RVILFSTQFMDEADILADRKVFLSQGKL--KCAGSSLFLKK 664
Cdd:PRK13646  160 LA--MNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQTDenKTIILVSHDMNEVARYADEVIVMKEGSIvsQTSPKELFKDK 237
                         250
                  ....*....|
gi 6005701    665 KWGIGYHLSL 674
Cdd:PRK13646  238 KKLADWHIGL 247
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
1257-1461 1.74e-17

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 83.50  E-value: 1.74e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1257 FSKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsGGGDALEF--------LGYCPQEN 1328
Cdd:cd03295    8 KRYGGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFI---DGEDIREQdpvelrrkIGYVIQQI 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1329 ALWPNLTVRQHLevyAAVKGLRKGDAEVAITRLVDALKLQDQlkSPVK-------TLSEGIKRKLCFVLSILGNPSVVLL 1401
Cdd:cd03295   85 GLFPHMTVEENI---ALVPKLLKWPKEKIRERADELLALVGL--DPAEfadryphELSGGQQQRVGVARALAADPPLLLM 159
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1402 DEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:cd03295  160 DEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGT 219
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
480-653 3.00e-17

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 83.12  E-value: 3.00e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     480 IRIRNVTKEYkgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEM--ADLENLS 557
Cdd:TIGR02315    2 LEVENLSKVY---PNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLrgKKLRKLR 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     558 KLTGVCPQSNVQFDFLTVRENL---RLFAK--IKGILPQ--EVDKE---------------------------------- 596
Cdd:TIGR02315   79 RRIGMIFQHYNLIERLTVLENVlhgRLGYKptWRSLLGRfsEEDKEralsalervgladkayqradqlsggqqqrvaiar 158
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701     597 -------IFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:TIGR02315  159 alaqqpdLILADEPIASLDPKTSKQVMDYLKRinKEDGITVIINLHQVDLAKKYADRIVGLKAGEI 224
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
1265-1456 3.19e-17

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 84.72  E-value: 3.19e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKP---TAGQVLLKG----SGGGDALE-----FLGYCPQE--NAL 1330
Cdd:COG0444   20 AVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGedllKLSEKELRkirgrEIQMIFQDpmTSL 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1331 WPNLTVRQHL-EVYAAVKGLRKGDAEvaiTRLVDALKLQdQLKSPVKT-------LSEGIKRKLCFVLSILGNPSVVLLD 1402
Cdd:COG0444  100 NPVMTVGDQIaEPLRIHGGLSKAEAR---ERAIELLERV-GLPDPERRldrypheLSGGMRQRVMIARALALEPKLLIAD 175
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701  1403 EPSTGMDPEGQQQmwqaIRATFR--NTERGA--LLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:COG0444  176 EPTTALDVTIQAQ----ILNLLKdlQRELGLaiLFITHDLGVVAEIADRVAVMYAGRI 229
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
1269-1460 3.87e-17

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 85.66  E-value: 3.87e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1269 VSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsgGGDALEFL---------GYCPQENALWPNLTVRQ- 1338
Cdd:PRK09536   22 VDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLV----AGDDVEALsaraasrrvASVPQDTSLSFEFDVRQv 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1339 -------HLEVYAAVKGLRKGDAEVAITRlVDALKLQDQlksPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPE 1411
Cdd:PRK09536   98 vemgrtpHRSRFDTWTETDRAAVERAMER-TGVAQFADR---PVTSLSGGERQRVLLARALAQATPVLLLDEPTASLDIN 173
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 6005701   1412 GQQQMWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIG 1460
Cdd:PRK09536  174 HQVRTLELVR-RLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAG 221
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
476-658 4.60e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 83.21  E-value: 4.60e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    476 GKEAIRIRNVTKEYK--GKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADL 553
Cdd:PRK13633    1 MNEMIKCKNVSYKYEsnEESTEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEENL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    554 ENLSKLTGVCPQSN--------VQFDFLTVRENLrlfakikGILPQEVDK------------------------------ 595
Cdd:PRK13633   81 WDIRNKAGMVFQNPdnqivatiVEEDVAFGPENL-------GIPPEEIRErvdeslkkvgmyeyrrhaphllsggqkqrv 153
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701    596 ----------EIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEAdILADRKVFLSQGKLKCAGS 658
Cdd:PRK13633  154 aiagilamrpECIIFDEPTAMLDPSGRREVVNTIKElnKKYGITIILITHYMEEA-VEADRIIVMDSGKVVMEGT 227
ABC2_membrane_3 pfam12698
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter ...
225-418 5.17e-17

ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter family pfam01061.


Pssm-ID: 463674 [Multi-domain]  Cd Length: 345  Bit Score: 84.36  E-value: 5.17e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     225 YLFSCIISFSSFIYYASV--NVTRER-KRMKALMTMMGLRDSAFWLSWGLLYAGFIFIMALFLALVIRSTqFIILSGFMV 301
Cdd:pfam12698  162 YLVGLILMIIILIGAAIIavSIVEEKeSRIKERLLVSGVSPLQYWLGKILGDFLVGLLQLLIILLLLFGI-GIPFGNLGL 240
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     302 VFSLFLLYGLSLVALAFLMSILVKKSFLTGLVVFLLT-VFWGCLGFTSLYRHLPASLEWILSLLSPFAFMLGMAQLLHld 380
Cdd:pfam12698  241 LLLLFLLYGLAYIALGYLLGSLFKNSEDAQSIIGIVIlLLSGFFGGLFPLEDPPSFLQWIFSIIPFFSPIDGLLRLIY-- 318
                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 6005701     381 YDLNSNAFPhpsdgsNLIvatnfMLAFDTCLYLALAIY 418
Cdd:pfam12698  319 GDSLWEIAP------SLI-----ILLLFAVVLLLLALL 345
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
480-658 5.56e-17

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 81.90  E-value: 5.56e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNklsEMADLENLSKL 559
Cdd:cd03300    1 IELENVSKFYGGFV----ALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGK---DITNLPPHKRP 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDKEI----------------------------------------FL 599
Cdd:cd03300   74 VNTVFQNYALFPHLTVFENIAFGLRLKKLPKAEIKERVaealdlvqlegyanrkpsqlsggqqqrvaiaralvnepkvLL 153
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   600 LDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:cd03300  154 LDEPLGALDLKLRKDMQLELKRlqKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGT 214
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
1229-1454 5.61e-17

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 86.26  E-value: 5.61e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1229 LNSTNFDEKPVIIASCLRKEYAGKR--KGcfskrknkiatrnVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQ 1306
Cdd:PRK15439    1 MQTSDTTAPPLLCARSISKQYSGVEvlKG-------------IDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGT 67
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1307 VLLKGS-----GGGDALEFLGY-CPQENALWPNLTVRQHLEVyaavkGL-RKGDAEVAITRLVDALKLQDQLKSPVKTLs 1379
Cdd:PRK15439   68 LEIGGNpcarlTPAKAHQLGIYlVPQEPLLFPNLSVKENILF-----GLpKRQASMQKMKQLLAALGCQLDLDSSAGSL- 141
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701   1380 EGIKRKLCFVL-SILGNPSVVLLDEPSTGMDPEGQQQMWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSG 1454
Cdd:PRK15439  142 EVADRQIVEILrGLMRDSRILILDEPTASLTPAETERLFSRIRE-LLAQGVGIVFISHKLPEIRQLADRISVMRDG 216
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
479-658 6.38e-17

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 82.00  E-value: 6.38e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   479 AIRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLEnlsK 558
Cdd:cd03296    2 SIEVRNVSKRFGDFV----ALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQE---R 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   559 LTGVCPQSNVQFDFLTVRENL----------------RLFAKIKGIL------------PQE----------------VD 594
Cdd:cd03296   75 NVGFVFQHYALFRHMTVFDNVafglrvkprserppeaEIRAKVHELLklvqldwladryPAQlsggqrqrvalaralaVE 154
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701   595 KEIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:cd03296  155 PKVLLLDEPFGALDAKVRKELRRWLRRlhDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGT 220
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
1267-1456 6.38e-17

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 85.84  E-value: 6.38e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----SGGGDALEF-LGYCP---QENALWPNLTVR 1337
Cdd:COG1129  269 RDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGkpvriRSPRDAIRAgIAYVPedrKGEGLVLDLSIR 348
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1338 Q-----HLEVYAAVKGLRKGDAEVAITRLVDALKL----QDQlksPVKTLSEGIKRKLcfVLS--ILGNPSVVLLDEPST 1406
Cdd:COG1129  349 EnitlaSLDRLSRGGLLDRRRERALAEEYIKRLRIktpsPEQ---PVGNLSGGNQQKV--VLAkwLATDPKVLILDEPTR 423
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 6005701  1407 GMDPEGQQQMWQAIRatfRNTERGA--LLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:COG1129  424 GIDVGAKAEIYRLIR---ELAAEGKavIVISSELPELLGLSDRILVMREGRI 472
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
480-658 6.73e-17

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 81.71  E-value: 6.73e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGkpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVtIYNNKlsemadlenlsKL 559
Cdd:cd03219    1 LEVRGLTKRFGG----LVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSV-LFDGE-----------DI 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCP------------QsNVQ-FDFLTVRENLRL-----------FAKIKGILPQEVDK-------------------- 595
Cdd:cd03219   65 TGLPPheiarlgigrtfQ-IPRlFPELTVLENVMVaaqartgsgllLARARREEREARERaeellervgladladrpage 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   596 -------------------EIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILfstqfMDEADI-----LADRKVFLSQ 650
Cdd:cd03219  144 lsygqqrrleiaralatdpKLLLLDEPAAGLNPEETEELAELIRElRERGITVL-----LVEHDMdvvmsLADRVTVLDQ 218

                 ....*...
gi 6005701   651 GKLKCAGS 658
Cdd:cd03219  219 GRVIAEGT 226
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
1273-1448 1.04e-16

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 81.69  E-value: 1.04e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1273 VRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsgggdALEFLGYCPQENALWPNLTVRQHLevYAAVKGlrKG 1352
Cdd:cd03237   22 ISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEI-------ELDTVSYKPQYIKADYEGTVRDLL--SSITKD--FY 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1353 DAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGAL 1432
Cdd:cd03237   91 THPYFKTEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRRFAENNEKTAF 170
                        170
                 ....*....|....*.
gi 6005701  1433 LTTHYMAEAEAVCDRV 1448
Cdd:cd03237  171 VVEHDIIMIDYLADRL 186
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
1265-1456 1.21e-16

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 84.96  E-value: 1.21e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----SGGGDALEfLG----YcpQENALWPNLT 1335
Cdd:PRK11288   19 ALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGqemrfASTTAALA-AGvaiiY--QELHLVPEMT 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1336 VRQ-----HLEVYAAVkgLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDP 1410
Cdd:PRK11288   96 VAEnlylgQLPHKGGI--VNRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIAFDEPTSSLSA 173
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 6005701   1411 EGQQQMWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK11288  174 REIEQLFRVIRE-LRAEGRVILYVSHRMEEIFALCDAITVFKDGRY 218
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
480-653 1.24e-16

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 82.05  E-value: 1.24e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYkgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI------YNNKlsemaDL 553
Cdd:PRK13639    2 LETRDLKYSY---PDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIkgepikYDKK-----SL 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    554 ENLSKLTGVCPQS------------NVQFDFLT-----------VRENLRL-----FAK---------------IKGILP 590
Cdd:PRK13639   74 LEVRKTVGIVFQNpddqlfaptveeDVAFGPLNlglskeevekrVKEALKAvgmegFENkpphhlsggqkkrvaIAGILA 153
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701    591 QEvdKEIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:PRK13639  154 MK--PEIIVLDEPTSGLDPMGASQIMKLLYDlNKEGITIIISTHDVDLVPVYADKVYVMSDGKI 215
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
480-664 1.29e-16

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 80.73  E-value: 1.29e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEY-KGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMaDLENLSK 558
Cdd:cd03254    3 IEFENVNFSYdEKKP----VLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDI-SRKSLRS 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   559 LTGVCPQSnvqfDFL---TVRENLRLF------------AKIKGI------LPQEVDKE--------------------- 596
Cdd:cd03254   78 MIGVVLQD----TFLfsgTIMENIRLGrpnatdeevieaAKEAGAhdfimkLPNGYDTVlgenggnlsqgerqllaiara 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   597 ------IFLLDEPTAGLDPFSRHQVWN---LLKERKTDRVI---LFSTQFmdeadilADRKVFLSQGKLKCAGS--SLFL 662
Cdd:cd03254  154 mlrdpkILILDEATSNIDTETEKLIQEaleKLMKGRTSIIIahrLSTIKN-------ADKILVLDDGKIIEEGThdELLA 226

                 ..
gi 6005701   663 KK 664
Cdd:cd03254  227 KK 228
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
455-648 1.36e-16

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 85.03  E-value: 1.36e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     455 DEMDADPSFHDSF---EQAPPEFQGKE--------AIRIRNVTKEYkgkPDKIEALKDLVFDIYEGQITAILGHSGAGKS 523
Cdd:TIGR02857  286 ARADGVAAAEALFavlDAAPRPLAGKApvtaapasSLEFSGVSVAY---PGRRPALRPVSFTVPPGERVALVGPSGAGKS 362
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     524 TLLNILSGLSVPTKGSVTIYNNKLSEmADLENLSKLTGVCPQSNVQFDfLTVRENLRLF------AKIKGI--------- 588
Cdd:TIGR02857  363 TLLNLLLGFVDPTEGSIAVNGVPLAD-ADADSWRDQIAWVPQHPFLFA-GTIAENIRLArpdasdAEIREAleragldef 440
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     589 ---LPQEVDKEI---------------------------FLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQfmDEA 638
Cdd:TIGR02857  441 vaaLPQGLDTPIgeggaglsggqaqrlalaraflrdaplLLLDEPTAHLDAETEAEVLEALRALAQGRTVLLVTH--RLA 518
                          250
                   ....*....|.
gi 6005701     639 DI-LADRKVFL 648
Cdd:TIGR02857  519 LAaLADRIVVL 529
cbiO PRK13637
energy-coupling factor transporter ATPase;
1263-1462 1.39e-16

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 82.02  E-value: 1.39e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1263 KIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG---SGGGDALEFL----GYCPQ--ENALWPN 1333
Cdd:PRK13637   20 KKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGvdiTDKKVKLSDIrkkvGLVFQypEYQLFEE 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1334 lTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQL---KSPVKtLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDP 1410
Cdd:PRK13637  100 -TIEKDIAFGPINLGLSEEEIENRVKRAMNIVGLDYEDykdKSPFE-LSGGQKRRVAIAGVVAMEPKILILDEPTAGLDP 177
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 6005701   1411 EGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSI 1462
Cdd:PRK13637  178 KGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTP 229
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
1269-1436 1.43e-16

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 79.84  E-value: 1.43e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1269 VSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDAL----EFLGYCPQENALWPNLTVRQHLEVYA 1344
Cdd:cd03231   19 LSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRdsiaRGLLYLGHAPGIKTTLSVLENLRFWH 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1345 AV---KGLRKGDAEVAITRLVDAlklqdqlksPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIR 1421
Cdd:cd03231   99 ADhsdEQVEEALARVGLNGFEDR---------PVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMA 169
                        170
                 ....*....|....*..
gi 6005701  1422 AtfrNTERG--ALLTTH 1436
Cdd:cd03231  170 G---HCARGgmVVLTTH 183
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
1259-1463 1.46e-16

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 81.32  E-value: 1.46e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1259 KRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsgGGDALEflGYCPQENALwpNLTV-R 1337
Cdd:COG4559   10 RLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRL----NGRPLA--AWSPWELAR--RRAVlP 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1338 QH---------LEVYA--AVKGLRKGDAEVAITR----LVDALKLQDQLkspVKTLSEGIK------RKLCFVL-SILGN 1395
Cdd:COG4559   82 QHsslafpftvEEVVAlgRAPHGSSAAQDRQIVRealaLVGLAHLAGRS---YQTLSGGEQqrvqlaRVLAQLWePVDGG 158
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701  1396 PSVVLLDEPSTGMDPEGQQQMWQAIRatfRNTERGA--------L-LTTHYmaeaeavCDRVAIMVSGRLRCIGSIQ 1463
Cdd:COG4559  159 PRWLFLDEPTSALDLAHQHAVLRLAR---QLARRGGgvvavlhdLnLAAQY-------ADRILLLHQGRLVAQGTPE 225
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
484-653 1.53e-16

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 80.39  E-value: 1.53e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   484 NVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLsVP----TKGSVTIYNNKLSEMADLENLSKL 559
Cdd:cd03234    8 DVGLKAKNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGR-VEgggtTSGQILFNGQPRKPDQFQKCVAYV 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 tgvcPQSNVQFDFLTVRENLRLFA---------------------------------KIKGILPQE-----------VDK 595
Cdd:cd03234   87 ----RQDDILLPGLTVRETLTYTAilrlprkssdairkkrvedvllrdlaltriggnLVKGISGGErrrvsiavqllWDP 162
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   596 EIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQfMDEADI--LADRKVFLSQGKL 653
Cdd:cd03234  163 KVLILDEPTSGLDSFTALNLVSTLSQlARRNRIVILTIH-QPRSDLfrLFDRILLLSSGEI 222
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
1260-1456 2.40e-16

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 79.92  E-value: 2.40e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1260 RKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITG-----DTKPTAGQVLLKG----SGGGDALEF---LGYCPQE 1327
Cdd:cd03260   10 YGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRlndliPGAPDEGEVLLDGkdiyDLDVDVLELrrrVGMVFQK 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1328 NALWPnLTVRQHLEVYAAVKGLRKGDAEVAITRlvDALK---LQDQLKSPVK--TLSEGIKRKLCFVLSILGNPSVVLLD 1402
Cdd:cd03260   90 PNPFP-GSIYDNVAYGLRLHGIKLKEELDERVE--EALRkaaLWDEVKDRLHalGLSGGQQQRLCLARALANEPEVLLLD 166
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 6005701  1403 EPSTGMDPEGQQQMWQAIRATfrNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:cd03260  167 EPTSALDPISTAKIEELIAEL--KKEYTIVIVTHNMQQAARVADRTAFLLNGRL 218
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
480-653 2.47e-16

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 82.16  E-value: 2.47e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEM--ADLENLS 557
Cdd:PRK11153    2 IELKNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALseKELRKAR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    558 KLTGVCPQsnvQFDFL---TVRENLRLFAKIKGILPQEVDK--------------------------------------- 595
Cdd:PRK11153   82 RQIGMIFQ---HFNLLssrTVFDNVALPLELAGTPKAEIKArvtellelvglsdkadrypaqlsggqkqrvaiaralasn 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701    596 -EIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:PRK11153  159 pKVLLCDEATSALDPATTRSILELLKDinRELGLTIVLITHEMDVVKRICDRVAVIDAGRL 219
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
1268-1454 2.80e-16

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 80.54  E-value: 2.80e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKgsgggDALEfLGYCPQENALWPN--LTVRQHLEVYAA 1345
Cdd:PRK09544   22 DVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRN-----GKLR-IGYVPQKLYLDTTlpLTVNRFLRLRPG 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1346 VKglrKGDAEVAITRlVDALKLQDQlksPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFR 1425
Cdd:PRK09544   96 TK---KEDILPALKR-VQAGHLIDA---PMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRR 168
                         170       180       190
                  ....*....|....*....|....*....|....
gi 6005701   1426 NTERGALLTTH----YMAEA-EAVCDRVAIMVSG 1454
Cdd:PRK09544  169 ELDCAVLMVSHdlhlVMAKTdEVLCLNHHICCSG 202
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
1273-1456 2.99e-16

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 79.07  E-value: 2.99e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1273 VRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDA--------LEFlgycpQENALWPNLTVRQHLEVyA 1344
Cdd:cd03298   21 FAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAppadrpvsMLF-----QENNLFAHLTVEQNVGL-G 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1345 AVKGLR-----KGDAEVAITRLvdalKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQA 1419
Cdd:cd03298   95 LSPGLKltaedRQAIEVALARV----GLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDL 170
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 6005701  1420 IRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:cd03298  171 VLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRI 207
cbiO PRK13637
energy-coupling factor transporter ATPase;
480-658 3.08e-16

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 80.86  E-value: 3.08e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEY-KGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYN-NKLSEMADLENLS 557
Cdd:PRK13637    3 IKIENLTHIYmEGTPFEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGvDITDKKVKLSDIR 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    558 KLTGVCPQ-------------------SN------------------VQFDFLTVRE---------NLRLFAkIKGILPQ 591
Cdd:PRK13637   83 KKVGLVFQypeyqlfeetiekdiafgpINlglseeeienrvkramniVGLDYEDYKDkspfelsggQKRRVA-IAGVVAM 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701    592 EvdKEIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:PRK13637  162 E--PKILILDEPTAGLDPKGRDEILNKIKElhKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGT 228
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
470-653 3.24e-16

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 80.47  E-value: 3.24e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   470 APPEFQGKEAIRIRNVTKEYKGKpdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLS--VP---TKGSVT--- 541
Cdd:COG1117    2 TAPASTLEPKIEVRNLNVYYGDK----QALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNdlIPgarVEGEILldg 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   542 --IYNNKLsemaDLENLSKLTG-VCPQSNVqfdF-LTVRENLRLFAKIKGI------------------LPQEV-DK--- 595
Cdd:COG1117   78 edIYDPDV----DVVELRRRVGmVFQKPNP---FpKSIYDNVAYGLRLHGIkskseldeiveeslrkaaLWDEVkDRlkk 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   596 -----------------------EIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADILADRKVFLSQGK 652
Cdd:COG1117  151 salglsggqqqrlciaralavepEVLLMDEPTSALDPISTAKIEELILELKKDYTIVIVTHNMQQAARVSDYTAFFYLGE 230

                 .
gi 6005701   653 L 653
Cdd:COG1117  231 L 231
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
1267-1436 3.74e-16

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 78.69  E-value: 3.74e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFLGYCPQENALWPNLTVRQHLEV 1342
Cdd:PRK13538   18 SGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGepirRQRDEYHQDLLYLGHQPGIKTELTALENLRF 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1343 YAAVKGLrkGDAEVAITRLvDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRA 1422
Cdd:PRK13538   98 YQRLHGP--GDDEALWEAL-AQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQGVARLEALLAQ 174
                         170
                  ....*....|....*.
gi 6005701   1423 tfrNTERG--ALLTTH 1436
Cdd:PRK13538  175 ---HAEQGgmVILTTH 187
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
1267-1404 4.04e-16

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 83.58  E-value: 4.04e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSgggdalEFLGYCPQENALWPNLTVRQ-----HLE 1341
Cdd:COG0488   15 DDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKG------LRIGYLPQEPPLDDDLTVLDtvldgDAE 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1342 VYAAVKGLRKG---------------------------DAEVAITRLVDALKL-QDQLKSPVKTLSEGIKRK--LCFVLs 1391
Cdd:COG0488   89 LRALEAELEELeaklaepdedlerlaelqeefealggwEAEARAEEILSGLGFpEEDLDRPVSELSGGWRRRvaLARAL- 167
                        170
                 ....*....|...
gi 6005701  1392 iLGNPSVVLLDEP 1404
Cdd:COG0488  168 -LSEPDLLLLDEP 179
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
1265-1411 4.13e-16

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 78.99  E-value: 4.13e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSG----GGDALEFL----GYCPQENALWPNLTV 1336
Cdd:cd03292   16 ALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDvsdlRGRAIPYLrrkiGVVFQDFRLLPDRNV 95
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701  1337 RQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPE 1411
Cdd:cd03292   96 YENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPD 170
cbiO PRK13641
energy-coupling factor transporter ATPase;
479-673 5.47e-16

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 80.26  E-value: 5.47e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYK-GKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLS 557
Cdd:PRK13641    2 SIKFENVDYIYSpGTPMEKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETGNKNLK 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    558 KL---TGVCPQ-SNVQFDFLTVRENLRL----F------AKIKGI-------LPQEV----------------------- 593
Cdd:PRK13641   82 KLrkkVSLVFQfPEAQLFENTVLKDVEFgpknFgfsedeAKEKALkwlkkvgLSEDLiskspfelsggqmrrvaiagvma 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    594 -DKEIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKL--KCAGSSLFLKKKWGIG 669
Cdd:PRK13641  162 yEPEILCLDEPAAGLDPEGRKEMMQLFKDyQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLikHASPKEIFSDKEWLKK 241

                  ....
gi 6005701    670 YHLS 673
Cdd:PRK13641  242 HYLD 245
galliderm_ABC TIGR03740
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ...
480-654 6.07e-16

gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.


Pssm-ID: 163452 [Multi-domain]  Cd Length: 223  Bit Score: 78.59  E-value: 6.07e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     480 IRIRNVTKEYKGKpdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEmADLENLskl 559
Cdd:TIGR03740    1 LETKNLSKRFGKQ----TAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGHPWTR-KDLHKI--- 72
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     560 tGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDK------------------------------------EIFLLDEP 603
Cdd:TIGR03740   73 -GSLIESPPLYENLTARENLKVHTTLLGLPDSRIDEvlnivdltntgkkkakqfslgmkqrlgiaiallnhpKLLILDEP 151
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 6005701     604 TAGLDPFSRHQVWNLLKERKTDRV-ILFSTQFMDEADILADRKVFLSQGKLK 654
Cdd:TIGR03740  152 TNGLDPIGIQELRELIRSFPEQGItVILSSHILSEVQQLADHIGIISEGVLG 203
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
1270-1465 1.01e-15

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 78.26  E-value: 1.01e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1270 SFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSgggdalEFLGYCP---------QENALWPNLTVRQHl 1340
Cdd:COG3840   19 DLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQ------DLTALPPaerpvsmlfQENNLFPHLTVAQN- 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1341 eVYAAVK-GLRKGDAEVAitRLVDALK---LQDQLKSPVKTLSEG------IKRklCFVLsilGNPsVVLLDEPSTGMDP 1410
Cdd:COG3840   92 -IGLGLRpGLKLTAEQRA--QVEQALErvgLAGLLDRLPGQLSGGqrqrvaLAR--CLVR---KRP-ILLLDEPFSALDP 162
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 6005701  1411 EGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHL 1465
Cdd:COG3840  163 ALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAAL 217
cbiO PRK13650
energy-coupling factor transporter ATPase;
1268-1468 1.07e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 79.39  E-value: 1.07e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGsgggDALeflgycpQENALWpnlTVRQHLE------ 1341
Cdd:PRK13650   25 DVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDG----DLL-------TEENVW---DIRHKIGmvfqnp 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1342 ----VYAAVK-----GLR-KG-DAEVAITRLVDALKL---QD-QLKSPVKtLSEGIKRKLCFVLSILGNPSVVLLDEPST 1406
Cdd:PRK13650   91 dnqfVGATVEddvafGLEnKGiPHEEMKERVNEALELvgmQDfKEREPAR-LSGGQKQRVAIAGAVAMRPKIIILDEATS 169
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701   1407 GMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAeAVCDRVAIMVSGRLRCIGSIQHLKSK 1468
Cdd:PRK13650  170 MLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTPRELFSR 230
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
477-657 1.11e-15

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 79.29  E-value: 1.11e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    477 KEAIRIRNVTKEYKGkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSE------- 549
Cdd:PRK13635    3 EEIIRVEHISFRYPD--AATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEetvwdvr 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    550 ------------------MAD-----LEN--------LSKLTGVCPQSNVQfDFLTvRENLRLFA------KIKGILPQE 592
Cdd:PRK13635   81 rqvgmvfqnpdnqfvgatVQDdvafgLENigvpreemVERVDQALRQVGME-DFLN-REPHRLSGgqkqrvAIAGVLALQ 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701    593 VDkeIFLLDEPTAGLDPFSRHQVWN---LLKERKTDRVILFsTQFMDEAdILADRKVFLSQGKLKCAG 657
Cdd:PRK13635  159 PD--IIILDEATSMLDPRGRREVLEtvrQLKEQKGITVLSI-THDLDEA-AQADRVIVMNKGEILEEG 222
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
1257-1470 1.18e-15

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 78.04  E-value: 1.18e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1257 FSKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDA-----LEFLGYCPQENALW 1331
Cdd:cd03254   10 FSYDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDIsrkslRSMIGVVLQDTFLF 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1332 PNlTVRQHL----------EVYAAVKglrkgdaEVAITRLVDALK--LQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVV 1399
Cdd:cd03254   90 SG-TIMENIrlgrpnatdeEVIEAAK-------EAGAHDFIMKLPngYDTVLGENGGNLSQGERQLLAIARAMLRDPKIL 161
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701  1400 LLDEPSTGMDPEGQQQMWQAIRATFRNteRGALLTTHYMAEAEAVcDRVAIMVSGRLRCIGSIQHLKSKFG 1470
Cdd:cd03254  162 ILDEATSNIDTETEKLIQEALEKLMKG--RTSIIIAHRLSTIKNA-DKILVLDDGKIIEEGTHDELLAKKG 229
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
1261-1456 1.29e-15

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 76.58  E-value: 1.29e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1261 KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG---SGGGDAL-EFLGYCPQENALWpNLTV 1336
Cdd:cd03247   13 QEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGvpvSDLEKALsSLISVLNQRPYLF-DTTL 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1337 RQHLevyaavkGLRkgdaevaitrlvdalklqdqlkspvktLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQM 1416
Cdd:cd03247   92 RNNL-------GRR---------------------------FSGGERQRLALARILLQDAPIVLLDEPTVGLDPITERQL 137
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 6005701  1417 WQAIRATFRNteRGALLTTHYMAEAEAVcDRVAIMVSGRL 1456
Cdd:cd03247  138 LSLIFEVLKD--KTLIWITHHLTGIEHM-DKILFLENGKI 174
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
1261-1456 1.36e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 78.98  E-value: 1.36e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1261 KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDaleflgycpqENALWpnlTVRQHL 1340
Cdd:PRK13633   21 TEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSD----------EENLW---DIRNKA 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1341 ---------EVYAAVKglrkgDAEVAI-------------TRLVDALK---LQDQLKSPVKTLSEGIKRKLCFVLSILGN 1395
Cdd:PRK13633   88 gmvfqnpdnQIVATIV-----EEDVAFgpenlgippeeirERVDESLKkvgMYEYRRHAPHLLSGGQKQRVAIAGILAMR 162
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   1396 PSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAeAVCDRVAIMVSGRL 1456
Cdd:PRK13633  163 PECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEA-VEADRIIVMDSGKV 222
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
1265-1474 1.42e-15

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 82.48  E-value: 1.42e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQ--VLlkgsgGGD--------------AleflgYCPQ-- 1326
Cdd:NF033858   16 ALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRveVL-----GGDmadarhrravcpriA-----YMPQgl 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1327 -ENaLWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRK--LCFVLsiLGNPSVVLLDE 1403
Cdd:NF033858   86 gKN-LYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKlgLCCAL--IHDPDLLILDE 162
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701   1404 PSTGMDPEGQQQMWQ---AIRAtfrntERGA---LLTTHYMAEAEAvCDRVAIMVSGRLRCIGSIQHLKSKFGKDYL 1474
Cdd:NF033858  163 PTTGVDPLSRRQFWElidRIRA-----ERPGmsvLVATAYMEEAER-FDWLVAMDAGRVLATGTPAELLARTGADTL 233
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
1268-1456 1.43e-15

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 78.13  E-value: 1.43e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS--------GGGDALEF---LGYCPQENALWPNLTV 1336
Cdd:COG4161   20 DINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHqfdfsqkpSEKAIRLLrqkVGMVFQQYNLWPHLTV 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1337 RQHL-EVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQ 1415
Cdd:COG4161  100 MENLiEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQ 179
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 6005701  1416 MWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:COG4161  180 VVEIIR-ELSQTGITQVIVTHEVEFARKVASQVVYMEKGRI 219
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
1252-1508 1.45e-15

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 81.86  E-value: 1.45e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1252 KRKGCFSKRKN---KIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALeflgycpqEN 1328
Cdd:PRK13545   23 KLKDLFFRSKDgeyHYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSAALIAI--------SS 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1329 ALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGM 1408
Cdd:PRK13545   95 GLNGQLTGIENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVG 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1409 DPEGQQQMWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFGkDYLLEMKVKNLAQVEPL 1488
Cdd:PRK13545  175 DQTFTKKCLDKMN-EFKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVDHYD-EFLKKYNQMSVEERKDF 252
                         250       260
                  ....*....|....*....|
gi 6005701   1489 HAEILRLFPQAARQERYSSL 1508
Cdd:PRK13545  253 REEQISQFQHGLLQEDQTGR 272
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
1262-1455 1.55e-15

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 77.99  E-value: 1.55e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1262 NKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFL----GYCPQENALWPN 1333
Cdd:cd03256   13 GKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGtdinKLKGKALRQLrrqiGMIFQQFNLIER 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1334 LTVRQH-----LEVYAAVKGLR----KGDAEVAItRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEP 1404
Cdd:cd03256   93 LSVLENvlsgrLGRRSTWRSLFglfpKEEKQRAL-AALERVGLLDKAYQRADQLSGGQQQRVAIARALMQQPKLILADEP 171
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 6005701  1405 STGMDPEGQQQMWQAIRATfrNTERG--ALLTTHYMAEAEAVCDRVAIMVSGR 1455
Cdd:cd03256  172 VASLDPASSRQVMDLLKRI--NREEGitVIVSLHQVDLAREYADRIVGLKDGR 222
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
478-657 2.41e-15

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 77.43  E-value: 2.41e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   478 EAIRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKG-SVTIYNNKLSEmADLENL 556
Cdd:COG1119    2 PLLELRNVTVRRGGKT----ILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGnDVRLFGERRGG-EDVWEL 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   557 SKLTGVCpqSNVQFDFLTVRENLR------LFAKIkGiLPQEVDK----------------------------------- 595
Cdd:COG1119   77 RKRIGLV--SPALQLRFPRDETVLdvvlsgFFDSI-G-LYREPTDeqrerarellellglahladrpfgtlsqgeqrrvl 152
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701   596 ---------EIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEadILA--DRKVFLSQGKLKCAG 657
Cdd:COG1119  153 iaralvkdpELLILDEPTAGLDLGARELLLALLDKlaAEGAPTLVLVTHHVEE--IPPgiTHVLLLKDGRVVAAG 225
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
480-665 2.98e-15

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 77.97  E-value: 2.98e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYkgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKG--------------------- 538
Cdd:PRK13636    6 LKVEELNYNY---SDGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGrilfdgkpidysrkglmklre 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    539 --------------SVTIY--------NNKLSE---MADLENLSKLTGVCPQSNVQFDFLTVRENLRlfAKIKGILPQEv 593
Cdd:PRK13636   83 svgmvfqdpdnqlfSASVYqdvsfgavNLKLPEdevRKRVDNALKRTGIEHLKDKPTHCLSFGQKKR--VAIAGVLVME- 159
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701    594 dKEIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAG--SSLFLKKK 665
Cdd:PRK13636  160 -PKVLVLDEPTAGLDPMGVSEIMKLLVEmqKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGnpKEVFAEKE 234
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
1229-1461 2.99e-15

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 79.61  E-value: 2.99e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1229 LNSTNFDEKPVIIASCLRKEYAGKrkgcfskrknkIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL 1308
Cdd:PRK09452    4 LNKQPSSLSPLVELRGISKSFDGK-----------EVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIM 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1309 LKGsgggdalEFLGYCPQEN----------ALWPNLTVRQHLEVyaavkGLR---KGDAEVAiTRLVDALK---LQDQLK 1372
Cdd:PRK09452   73 LDG-------QDITHVPAENrhvntvfqsyALFPHMTVFENVAF-----GLRmqkTPAAEIT-PRVMEALRmvqLEEFAQ 139
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1373 SPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMV 1452
Cdd:PRK09452  140 RKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMR 219

                  ....*....
gi 6005701   1453 SGRLRCIGS 1461
Cdd:PRK09452  220 DGRIEQDGT 228
cbiO PRK13641
energy-coupling factor transporter ATPase;
1263-1468 4.08e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 77.56  E-value: 4.08e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1263 KIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----SGGGDALEFL----GYCPQ--ENALW 1331
Cdd:PRK13641   20 KKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGyhitpETGNKNLKKLrkkvSLVFQfpEAQLF 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1332 PNlTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQL--KSPVKtLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMD 1409
Cdd:PRK13641  100 EN-TVLKDVEFGPKNFGFSEDEAKEKALKWLKKVGLSEDLisKSPFE-LSGGQMRRVAIAGVMAYEPEILCLDEPAAGLD 177
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701   1410 PEGQQQMWQairaTFRNTERGA---LLTTHYMAEAEAVCDRVAIMVSGRLrcigsIQHLKSK 1468
Cdd:PRK13641  178 PEGRKEMMQ----LFKDYQKAGhtvILVTHNMDDVAEYADDVLVLEHGKL-----IKHASPK 230
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
1264-1455 4.36e-15

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 76.95  E-value: 4.36e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1264 IATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSgggdalEFLGYCPQENA-------------- 1329
Cdd:PRK11300   19 LAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQ------HIEGLPGHQIArmgvvrtfqhvrlf 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1330 ----LWPNLTVRQHLEVYAAV-------KGLRKGDAEvAITRL---VDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGN 1395
Cdd:PRK11300   93 remtVIENLLVAQHQQLKTGLfsgllktPAFRRAESE-ALDRAatwLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQ 171
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1396 PSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGR 1455
Cdd:PRK11300  172 PEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGT 231
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
1265-1463 5.47e-15

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 79.83  E-value: 5.47e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSG-----GGDALEF-LGYCPQENALWPNLTVRQ 1338
Cdd:PRK09700   20 ALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINynkldHKLAAQLgIGIIYQELSVIDELTVLE 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1339 HLEV----YAAVKGLRKGD---AEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPE 1411
Cdd:PRK09700  100 NLYIgrhlTKKVCGVNIIDwreMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDAKVIIMDEPTSSLTNK 179
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 6005701   1412 GQQQMWqAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQ 1463
Cdd:PRK09700  180 EVDYLF-LIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVS 230
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
480-653 7.17e-15

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 75.14  E-value: 7.17e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYkgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMAD--LENLS 557
Cdd:cd03292    1 IEFINVTKTY---PNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGraIPYLR 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   558 KLTGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDKE----------------------------------------I 597
Cdd:cd03292   78 RKIGVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRvpaalelvglshkhralpaelsggeqqrvaiaraivnsptI 157
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701   598 FLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:cd03292  158 LIADEPTGNLDPDTTWEIMNLLKKiNKAGTTVVVATHAKELVDTTRHRVIALERGKL 214
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
495-653 8.41e-15

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 75.97  E-value: 8.41e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    495 KIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLS-----VPTKGSVtIYN--NKLSEMADLENLSKLTGVCPQSN 567
Cdd:PRK14239   17 KKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNdlnpeVTITGSI-VYNghNIYSPRTDTVDLRKEIGMVFQQP 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    568 VQFDFlTVREN----LRLFA-KIKGILPQEVDK----------------------------------------EIFLLDE 602
Cdd:PRK14239   96 NPFPM-SIYENvvygLRLKGiKDKQVLDEAVEKslkgasiwdevkdrlhdsalglsggqqqrvciarvlatspKIILLDE 174
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 6005701    603 PTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:PRK14239  175 PTSALDPISAGKIEETLLGLKDDYTMLLVTRSMQQASRISDRTGFFLDGDL 225
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
1265-1451 9.30e-15

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 79.25  E-value: 9.30e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsGGGDALEF--------LGYCPQENALWPNlTV 1336
Cdd:TIGR02857  337 ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAV---NGVPLADAdadswrdqIAWVPQHPFLFAG-TI 412
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1337 RQHLEVY---AAVKGLRKGDAEVAITRLVDALK--LQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPE 1411
Cdd:TIGR02857  413 AENIRLArpdASDAEIREALERAGLDEFVAALPqgLDTPIGEGGAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAE 492
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 6005701    1412 GQQQMWQAIRATFRNteRGALLTTHYMAEAEAvCDRVAIM 1451
Cdd:TIGR02857  493 TEAEVLEALRALAQG--RTVLLVTHRLALAAL-ADRIVVL 529
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
480-652 9.75e-15

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 72.87  E-value: 9.75e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNklSEMADLENLSKl 559
Cdd:cd03221    1 IELENLSKTYGGKL----LLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGST--VKIGYFEQLSG- 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 tGvcpqsnvqfdfltvrENLRL-FAKikgILPQEVDkeIFLLDEPTAGLDPFSRHQVWNLLKE-RKTdrVILFS--TQFM 635
Cdd:cd03221   74 -G---------------EKMRLaLAK---LLLENPN--LLLLDEPTNHLDLESIEALEEALKEyPGT--VILVShdRYFL 130
                        170
                 ....*....|....*..
gi 6005701   636 DEadiLADRKVFLSQGK 652
Cdd:cd03221  131 DQ---VATKIIELEDGK 144
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
1245-1456 1.07e-14

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 77.53  E-value: 1.07e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1245 LRKEYAGKRKGcfskrknKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsgGGDALEFLGyc 1324
Cdd:PRK11153    7 ISKVFPQGGRT-------IHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLV----DGQDLTALS-- 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1325 pqENALwpNLTVR------QHLE------VYAAV------KGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKL 1386
Cdd:PRK11153   74 --EKEL--RKARRqigmifQHFNllssrtVFDNValplelAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRV 149
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701   1387 CFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATfrNTERG--ALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK11153  150 AIARALASNPKVLLCDEATSALDPATTRSILELLKDI--NRELGltIVLITHEMDVVKRICDRVAVIDAGRL 219
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
480-577 1.52e-14

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 75.12  E-value: 1.52e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADlENLSKL 559
Cdd:COG4604    2 IEIKNVSKRYGGKV----VLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPS-RELAKR 76
                         90
                 ....*....|....*...
gi 6005701   560 TGVCPQSNVQFDFLTVRE 577
Cdd:COG4604   77 LAILRQENHINSRLTVRE 94
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
1253-1475 1.58e-14

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 75.61  E-value: 1.58e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1253 RKGCFSKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----SGGGDALEFLGYC--- 1324
Cdd:PRK13652    7 RDLCYSYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGepitkENIREVRKFVGLVfqn 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1325 PQENALWPnlTVRQHLEVYAAVKGLrkgDAEVAITRLVDALK---LQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLL 1401
Cdd:PRK13652   87 PDDQIFSP--TVEQDIAFGPINLGL---DEETVAHRVSSALHmlgLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVL 161
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701   1402 DEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLkskFGKDYLL 1475
Cdd:PRK13652  162 DEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEI---FLQPDLL 232
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
480-628 1.63e-14

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 73.02  E-value: 1.63e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEmADLENLSKL 559
Cdd:cd03246    1 LEVENVSFRYPG--AEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQ-WDPNELGDH 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFlTVRENlrlfakikgILP----QEV--------DKEIFLLDEPTAGLDPFSRHQVWNL---LKERKT 624
Cdd:cd03246   78 VGYLPQDDELFSG-SIAEN---------ILSggqrQRLglaralygNPRILVLDEPNSHLDVEGERALNQAiaaLKAAGA 147

                 ....
gi 6005701   625 DRVI 628
Cdd:cd03246  148 TRIV 151
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
480-648 1.83e-14

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 74.50  E-value: 1.83e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLSKL 559
Cdd:cd03218    1 LRAENLSKRYGKRK----VVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRARLG 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDKEI----------------------------------------FL 599
Cdd:cd03218   77 IGYLPQEASIFRKLTVEENILAVLEIRGLSKKEREEKLeelleefhithlrkskasslsggerrrveiaralatnpkfLL 156
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701   600 LDEPTAGLDPFSRHQVWNL---LKERK----------------TDRV-ILFSTQFMDE---ADILAD---RKVFL 648
Cdd:cd03218  157 LDEPFAGVDPIAVQDIQKIikiLKDRGigvlitdhnvretlsiTDRAyIIYEGKVLAEgtpEEIAANelvRKVYL 231
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
1246-1471 1.88e-14

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 78.55  E-value: 1.88e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1246 RKEYAGKRKGCFSKRKN-KIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKP---TAGQVLLKGSGGGdaLEFL 1321
Cdd:TIGR00955   20 WKQLVSRLRGCFCRERPrKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKgvkGSGSVLLNGMPID--AKEM 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1322 ----GYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITR---LVDALKLQD------QLKSPVKTLSEGIKRKLCF 1388
Cdd:TIGR00955   98 raisAYVQQDDLFIPTLTVREHLMFQAHLRMPRRVTKKEKRERvdeVLQALGLRKcantriGVPGRVKGLSGGERKRLAF 177
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1389 VLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRAtFRNTERGALLTTHyMAEAEAVC--DRVAIMVSGRLRCIGSIQHLK 1466
Cdd:TIGR00955  178 ASELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKG-LAQKGKTIICTIH-QPSSELFElfDKIILMAEGRVAYLGSPDQAV 255

                   ....*
gi 6005701    1467 SKFGK 1471
Cdd:TIGR00955  256 PFFSD 260
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
1265-1468 2.22e-14

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 75.27  E-value: 2.22e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS-------GGGDALEFLGYCPQ--ENALWpNLT 1335
Cdd:PRK13636   21 ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKpidysrkGLMKLRESVGMVFQdpDNQLF-SAS 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1336 VRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQ 1415
Cdd:PRK13636  100 VYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSE 179
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 6005701   1416 MWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSK 1468
Cdd:PRK13636  180 IMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVFAE 232
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
480-652 2.26e-14

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 75.12  E-value: 2.26e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKE-YKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLE---N 555
Cdd:COG1101    2 LELKNLSKTfNPGTVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKrakY 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   556 LSK-----LTGVCPQsnvqfdfLTVRENLRLFAK-------IKGILPQEVDK---------------------------- 595
Cdd:COG1101   82 IGRvfqdpMMGTAPS-------MTIEENLALAYRrgkrrglRRGLTKKRRELfrellatlglglenrldtkvgllsggqr 154
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701   596 -------------EIFLLDEPTAGLDPFSRHQVWNLlkerkTDRVI-------LFSTQFMDEADILADRKVFLSQGK 652
Cdd:COG1101  155 qalsllmatltkpKLLLLDEHTAALDPKTAALVLEL-----TEKIVeennlttLMVTHNMEQALDYGNRLIMMHEGR 226
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
1267-1461 2.46e-14

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 73.33  E-value: 2.46e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITG--DTKPTAGQVLLKGSgggDALEFLgycPQENAlwpnltvrqhlevya 1344
Cdd:cd03217   17 KGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGhpKYEVTEGEILFKGE---DITDLP---PEERA--------------- 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1345 avkglRKG-----DAEVAITrlvdALKLQDQLKSPVKTLSEGiKRKLCFVLSILG-NPSVVLLDEPSTGMDPEGQQQMWQ 1418
Cdd:cd03217   76 -----RLGiflafQYPPEIP----GVKNADFLRYVNEGFSGG-EKKRNEILQLLLlEPDLAILDEPDSGLDIDALRLVAE 145
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 6005701  1419 AIRaTFRNTERGALLTTHYMAEAEAV-CDRVAIMVSGRLRCIGS 1461
Cdd:cd03217  146 VIN-KLREEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSGD 188
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
499-651 2.48e-14

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 74.04  E-value: 2.48e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     499 LKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSE-----MADLENLSKL-------------T 560
Cdd:TIGR01184    1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEpgpdrMVVFQNYSLLpwltvrenialavD 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     561 GVCPQSNVQFDFLTVRENLRLF----------AKIKGILPQEV--------DKEIFLLDEPTAGLDPFSRHQVWN-LLKE 621
Cdd:TIGR01184   81 RVLPDLSKSERRAIVEEHIALVglteaadkrpGQLSGGMKQRVaiaralsiRPKVLLLDEPFGALDALTRGNLQEeLMQI 160
                          170       180       190
                   ....*....|....*....|....*....|.
gi 6005701     622 RKTDRV-ILFSTQFMDEADILADRKVFLSQG 651
Cdd:TIGR01184  161 WEEHRVtVLMVTHDVDEALLLSDRVVMLTNG 191
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
1267-1475 2.87e-14

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 74.06  E-value: 2.87e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDA-LEFL----GYCPQENALWpNLTVRQHLE 1341
Cdd:cd03252   19 DNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALAdPAWLrrqvGVVLQENVLF-NRSIRDNIA 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1342 VYAAVKGLRKgdaEVAITRLVDALKLQDQLKSPVKT--------LSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQ 1413
Cdd:cd03252   98 LADPGMSMER---VIEAAKLAGAHDFISELPEGYDTivgeqgagLSGGQRQRIAIARALIHNPRILIFDEATSALDYESE 174
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701  1414 QQMWQAIRATFRNteRGALLTTHYMAEAEAVcDRVAIMVSGRLRCIGSIQHLKSKFGKDYLL 1475
Cdd:cd03252  175 HAIMRNMHDICAG--RTVIIIAHRLSTVKNA-DRIIVMEKGRIVEQGSHDELLAENGLYAYL 233
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
479-657 2.99e-14

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 74.77  E-value: 2.99e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYKgkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLSK 558
Cdd:PRK13647    4 IIEVEDLHFRYK---DGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWVRSK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    559 LTGVCPQSNVQFDFLTVRE-------NLRLFAK-----------------------------------IKGILPqeVDKE 596
Cdd:PRK13647   81 VGLVFQDPDDQVFSSTVWDdvafgpvNMGLDKDeverrveealkavrmwdfrdkppyhlsygqkkrvaIAGVLA--MDPD 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701    597 IFLLDEPTAGLDPFSRHQV----WNLLKERKTdrvILFSTQFMDEADILADRKVFLSQGKLKCAG 657
Cdd:PRK13647  159 VIVLDEPMAYLDPRGQETLmeilDRLHNQGKT---VIVATHDVDLAAEWADQVIVLKEGRVLAEG 220
cbiO PRK13643
energy-coupling factor transporter ATPase;
480-658 3.82e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 74.77  E-value: 3.82e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYK-GKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYN---NKLSEMADLEN 555
Cdd:PRK13643    2 IKFEKVNYTYQpNSPFASRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDivvSSTSKQKEIKP 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    556 LSKLTGVC---PQS---------NVQF---DFLTVRENLRLFA-----------------------------KIKGILPQ 591
Cdd:PRK13643   82 VRKKVGVVfqfPESqlfeetvlkDVAFgpqNFGIPKEKAEKIAaeklemvgladefwekspfelsggqmrrvAIAGILAM 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701    592 EvdKEIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:PRK13643  162 E--PEVLVLDEPTAGLDPKARIEMMQLFESiHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGT 227
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
1265-1456 3.91e-14

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 74.34  E-value: 3.91e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS----GGGDALEF---LGYC---PQENALWPnl 1334
Cdd:PRK13639   17 ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEpikyDKKSLLEVrktVGIVfqnPDDQLFAP-- 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1335 TVRQHLEVYAAVKGLRKGDAEvaiTRLVDALK---LQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPE 1411
Cdd:PRK13639   95 TVEEDVAFGPLNLGLSKEEVE---KRVKEALKavgMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPM 171
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 6005701   1412 GQQQMwqaIRATFRNTERG--ALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK13639  172 GASQI---MKLLYDLNKEGitIIISTHDVDLVPVYADKVYVMSDGKI 215
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
1264-1474 8.54e-14

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 75.45  E-value: 8.54e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1264 IATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG---SGGGDA------LEFLGYCPQENALWPNL 1334
Cdd:PRK10070   42 LGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGvdiAKISDAelrevrRKKIAMVFQSFALMPHM 121
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1335 TVRQHLEVYAAVKGLrkgDAEVAITRLVDALK---LQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPE 1411
Cdd:PRK10070  122 TVLDNTAFGMELAGI---NAEERREKALDALRqvgLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPL 198
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6005701   1412 GQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFGKDYL 1474
Cdd:PRK10070  199 IRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYV 261
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
1259-1484 9.90e-14

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 73.31  E-value: 9.90e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1259 KRKNK--IATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALeflgycpqeNA-LWPNLT 1335
Cdd:PRK13546   31 KHKNKtfFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGEVSVIAI---------SAgLSGQLT 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1336 VRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQ 1415
Cdd:PRK13546  102 GIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQK 181
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701   1416 MWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFgKDYLLEMKVKNLAQ 1484
Cdd:PRK13546  182 CLDKIY-EFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKY-EAFLNDFKKKSKAE 248
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
1260-1459 1.06e-13

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 75.59  E-value: 1.06e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1260 RKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----SGGGDALE----FLGYCPQENAL 1330
Cdd:PRK09700  273 SRDRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGkdispRSPLDAVKkgmaYITESRRDNGF 352
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1331 WPNLTVRQHLEVYAAVKGLRKGDA-----EVAITRLVDALKLQDQLKSP-----VKTLSEGIKRKLCFVLSILGNPSVVL 1400
Cdd:PRK09700  353 FPNFSIAQNMAISRSLKDGGYKGAmglfhEVDEQRTAENQRELLALKCHsvnqnITELSGGNQQKVLISKWLCCCPEVII 432
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701   1401 LDEPSTGMDPEGQQQMWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCI 1459
Cdd:PRK09700  433 FDEPTRGIDVGAKAEIYKVMR-QLADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQI 490
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
480-658 1.24e-13

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 71.76  E-value: 1.24e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMaDLENLSKL 559
Cdd:cd03244    3 IEFKNVSLRYR--PNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKI-GLHDLRSR 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFlTVRENLRLF--------------AKIKGILPQEVDK------------------------------ 595
Cdd:cd03244   80 ISIIPQDPVLFSG-TIRSNLDPFgeysdeelwqalerVGLKEFVESLPGGldtvveeggenlsvgqrqllclarallrks 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701   596 EIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQ----FMDeadilADRKVFLSQGKLKCAGS 658
Cdd:cd03244  159 KILVLDEATASVDPETDALIQKTIREAFKDCTVLTIAHrldtIID-----SDRILVLDKGRVVEFDS 220
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
480-579 1.31e-13

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 75.59  E-value: 1.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYKGkpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIyNNKLSEMADLENLSKL 559
Cdd:PRK09700    6 ISMAGIGKSFGP----VHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITI-NNINYNKLDHKLAAQL 80
                          90       100
                  ....*....|....*....|.
gi 6005701    560 -TGVCPQSNVQFDFLTVRENL 579
Cdd:PRK09700   81 gIGIIYQELSVIDELTVLENL 101
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
480-658 1.84e-13

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 75.09  E-value: 1.84e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYKGkpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMAdlENLSKL 559
Cdd:PRK15439   12 LCARSISKQYSG----VEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLT--PAKAHQ 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    560 TGV--CPQSNVQFDFLTVRENLrLF---------AKIKGILPQ--------------EV--------------DKEIFLL 600
Cdd:PRK15439   86 LGIylVPQEPLLFPNLSVKENI-LFglpkrqasmQKMKQLLAAlgcqldldssagslEVadrqiveilrglmrDSRILIL 164
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701    601 DEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:PRK15439  165 DEPTASLTPAETERLFSRIRElLAQGVGIVFISHKLPEIRQLADRISVMRDGTIALSGK 223
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
480-672 1.89e-13

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 71.80  E-value: 1.89e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPDkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMAdLENLSKL 559
Cdd:cd03249    1 IEFKNVSFRYPSRPD-VPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLN-LRWLRSQ 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDfLTVRENLRL------------FAKIKGI------LPQEVDKE------------------------- 596
Cdd:cd03249   79 IGLVSQEPVLFD-GTIAENIRYgkpdatdeeveeAAKKANIhdfimsLPDGYDTLvgergsqlsggqkqriaiarallrn 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   597 --IFLLDEPTAGLDPFSRHQVWNLLKERKTDRVIL-----FSTqfmdeadIL-ADRKVFLSQGKLKCAGSSLFLKKKWGI 668
Cdd:cd03249  158 pkILLLDEATSALDAESEKLVQEALDRAMKGRTTIviahrLST-------IRnADLIAVLQNGQVVEQGTHDELMAQKGV 230

                 ....
gi 6005701   669 GYHL 672
Cdd:cd03249  231 YAKL 234
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
511-667 1.98e-13

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 73.76  E-value: 1.98e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    511 ITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLS---KLTGVCPQSNVQFDFLTVRENLR------- 580
Cdd:PRK11144   26 ITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKGICLPpekRRIGYVFQDARLFPHYKVRGNLRygmaksm 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    581 --LFAKIKGIL---------P--------QEV--------DKEIFLLDEPTAGLDPFSRHQVWNLLkERKTDRV---ILF 630
Cdd:PRK11144  106 vaQFDKIVALLgieplldryPgslsggekQRVaigralltAPELLLMDEPLASLDLPRKRELLPYL-ERLAREInipILY 184
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 6005701    631 STQFMDEADILADRKVFLSQGKLKCAGSslfLKKKWG 667
Cdd:PRK11144  185 VSHSLDEILRLADRVVVLEQGKVKAFGP---LEEVWA 218
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
480-657 2.03e-13

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 72.48  E-value: 2.03e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYKGkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVtIYNNKLSEMADLENLSKL 559
Cdd:PRK13648    8 IVFKNVSFQYQS--DASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEI-FYNNQAITDDNFEKLRKH 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    560 TGVCPQ--------SNVQFDFLTVRENLRL-FAKIKGILPQ---EVD-----------------------------KEIF 598
Cdd:PRK13648   85 IGIVFQnpdnqfvgSIVKYDVAFGLENHAVpYDEMHRRVSEalkQVDmleradyepnalsggqkqrvaiagvlalnPSVI 164
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701    599 LLDEPTAGLDPFSRHQVWNLLKERKTDR--VILFSTQFMDEAdILADRKVFLSQGKLKCAG 657
Cdd:PRK13648  165 ILDEATSMLDPDARQNLLDLVRKVKSEHniTIISITHDLSEA-MEADHVIVMNKGTVYKEG 224
ABC2_membrane_3 pfam12698
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter ...
883-1128 2.19e-13

ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter family pfam01061.


Pssm-ID: 463674 [Multi-domain]  Cd Length: 345  Bit Score: 73.58  E-value: 2.19e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     883 ASIDDFIQSVEHQNI--ALEVDAFGTRNGTDDPSYNgaITVCCNEKNYSFSLACNAKRLNCFPVLMDIVSNGLLGMVKPS 960
Cdd:pfam12698   65 DSEEEAKEALKNGKIdgLLVIPKGFSKDLLKGESAT--VTVYINSSNLLVSKLILNALQSLLQQLNASALVLLLEALSTS 142
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     961 VHIRTErSTFLENGQDNPIGFLAYIMFWLVLTSSCPpYIAMSSIDDYKNRARSQLRISGLSPSAYWFGQALVDVSLYFLV 1040
Cdd:pfam12698  143 APIPVE-STPLFNPQSGYAYYLVGLILMIIILIGAA-IIAVSIVEEKESRIKERLLVSGVSPLQYWLGKILGDFLVGLLQ 220
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1041 FVFIYLMSYISNFEDMLLTIIHIIQIPcavgYSFSLIFMTYVISFIFRKGRKNSGIWSFCFYVVTVFSVAGFAFSIFESD 1120
Cdd:pfam12698  221 LLIILLLLFGIGIPFGNLGLLLLLFLL----YGLAYIALGYLLGSLFKNSEDAQSIIGIVILLLSGFFGGLFPLEDPPSF 296

                   ....*...
gi 6005701    1121 IPFIFTFL 1128
Cdd:pfam12698  297 LQWIFSII 304
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
1262-1436 2.25e-13

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 74.70  E-value: 2.25e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1262 NKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEFL-GYCPQENALWpNLTV 1336
Cdd:TIGR02868  347 APPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGvpvsSLDQDEVRRRvSVCAQDAHLF-DTTV 425
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1337 RQHL----------EVYAAVKGLRKGDaevaitrLVDAlkLQDQLKSPV----KTLSEGIKRKLCFVLSILGNPSVVLLD 1402
Cdd:TIGR02868  426 RENLrlarpdatdeELWAALERVGLAD-------WLRA--LPDGLDTVLgeggARLSGGERQRLALARALLADAPILLLD 496
                          170       180       190
                   ....*....|....*....|....*....|....
gi 6005701    1403 EPSTGMDPEGQQQMWQAIRATfrNTERGALLTTH 1436
Cdd:TIGR02868  497 EPTEHLDAETADELLEDLLAA--LSGRTVVLITH 528
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
1267-1461 2.31e-13

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 74.82  E-value: 2.31e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsgGG--------DAL-EFLGYCPQENALWpNLTVR 1337
Cdd:COG1132  357 KDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILI----DGvdirdltlESLrRQIGVVPQDTFLF-SGTIR 431
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1338 QHL----------EVYAAVKglrkgdaEVAITRLVDALKlqDQLKSPV----KTLSEGIKRKLCFVLSILGNPSVVLLDE 1403
Cdd:COG1132  432 ENIrygrpdatdeEVEEAAK-------AAQAHEFIEALP--DGYDTVVgergVNLSGGQRQRIAIARALLKDPPILILDE 502
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701  1404 PSTGMDPEGQQQMWQAIRATFRNteRGALLTTHYMAEAEAvCDRVAIMVSGRLRCIGS 1461
Cdd:COG1132  503 ATSALDTETEALIQEALERLMKG--RTTIVIAHRLSTIRN-ADRILVLDDGRIVEQGT 557
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
1257-1456 2.51e-13

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 73.19  E-value: 2.51e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1257 FSKRKNKI-ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDAL-EF---LGYCPQE 1327
Cdd:COG1135   11 FPTKGGPVtALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGvdltALSERELrAArrkIGMIFQH 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1328 NALWPNLTVRQH----LEvyaaVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEG------IKRKLCfvlsilGNPS 1397
Cdd:COG1135   91 FNLLSSRTVAENvalpLE----IAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGqkqrvgIARALA------NNPK 160
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6005701  1398 VVLLDEPSTGMDPEGQQQmwqaIRATFR--NTERGA--LLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:COG1135  161 VLLCDEATSALDPETTRS----ILDLLKdiNRELGLtiVLITHEMDVVRRICDRVAVLENGRI 219
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
479-644 2.52e-13

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 74.28  E-value: 2.52e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   479 AIRIRNVTKEYKGkpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLSK 558
Cdd:COG1129    4 LLEMRGISKSFGG----VKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRDAQAA 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   559 LTGVCPQSNVQFDFLTVRENL----------------------RLFAKIkGI----------LP----QEV--------D 594
Cdd:COG1129   80 GIAIIHQELNLVPNLSVAENIflgreprrgglidwramrrrarELLARL-GLdidpdtpvgdLSvaqqQLVeiaralsrD 158
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 6005701   595 KEIFLLDEPTAGLDPFSRHQVWNLLKERKTDRV-ILFSTQFMDEADILADR 644
Cdd:COG1129  159 ARVLILDEPTASLTEREVERLFRIIRRLKAQGVaIIYISHRLDEVFEIADR 209
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
1267-1455 2.77e-13

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 71.18  E-value: 2.77e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDALEF---LGYCPQENALWPNLTVRQH 1339
Cdd:COG1126   18 KGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGedltDSKKDINKLrrkVGMVFQQFNLFPHLTVLEN 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1340 LeVYA--AVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEG------IKRKLCFvlsilgNPSVVLLDEPSTGMDPE 1411
Cdd:COG1126   98 V-TLApiKVKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGqqqrvaIARALAM------EPKVMLFDEPTSALDPE 170
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 6005701  1412 gqqqMWQAIRATFRN-TERGA--LLTTHYMAEAEAVCDRVAIMVSGR 1455
Cdd:COG1126  171 ----LVGEVLDVMRDlAKEGMtmVVVTHEMGFAREVADRVVFMDGGR 213
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
480-581 2.94e-13

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 70.98  E-value: 2.94e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSeMADLENLSKL 559
Cdd:cd03252    1 ITFEHVRFRYK--PDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLA-LADPAWLRRQ 77
                         90       100
                 ....*....|....*....|..
gi 6005701   560 TGVCPQSNVQFDfLTVRENLRL 581
Cdd:cd03252   78 VGVVLQENVLFN-RSIRDNIAL 98
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
501-657 2.97e-13

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 70.40  E-value: 2.97e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   501 DLVFDIyEGQITAILGHSGAGKSTLLNILSGLSVPTKGSV----TIYNNKLSEMaDLENLSKLTGVCPQSNVQFDFLTVR 576
Cdd:cd03297   16 KIDFDL-NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIvlngTVLFDSRKKI-NLPPQQRKIGLVFQQYALFPHLNVR 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   577 ENL-----RLFAKIKGILPQEV---------------------------------DKEIFLLDEPTAGLDPFSRHQVWNL 618
Cdd:cd03297   94 ENLafglkRKRNREDRISVDELldllgldhllnrypaqlsggekqrvalaralaaQPELLLLDEPFSALDRALRLQLLPE 173
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 6005701   619 LKERKTDRVI--LFSTQFMDEADILADRKVFLSQGKLKCAG 657
Cdd:cd03297  174 LKQIKKNLNIpvIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
1268-1474 4.17e-13

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 70.81  E-value: 4.17e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----SGGGDALEFL------GYCPQENALWPNLTV 1336
Cdd:PRK11124   20 DITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGnhfdfSKTPSDKAIRelrrnvGMVFQQYNLWPHLTV 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1337 RQHL-EVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQ 1415
Cdd:PRK11124  100 QQNLiEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQ 179
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6005701   1416 MWQAIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLK----SKFgKDYL 1474
Cdd:PRK11124  180 IVSIIRE-LAETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASCFTqpqtEAF-KNYL 240
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
1267-1461 4.46e-13

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 69.75  E-value: 4.46e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS-----GGGDALEFLGYCPQENALWPNlTVRQHLE 1341
Cdd:cd03369   25 KNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIdistiPLEDLRSSLTIIPQDPTLFSG-TIRSNLD 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1342 VYAavkglRKGDAEvaitrLVDALKlqdqLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIR 1421
Cdd:cd03369  104 PFD-----EYSDEE-----IYGALR----VSEGGLNLSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQKTIR 169
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 6005701  1422 ATFRNTergALLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:cd03369  170 EEFTNS---TILTIAHRLRTIIDYDKILVMDAGEVKEYDH 206
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
479-653 4.52e-13

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 70.54  E-value: 4.52e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   479 AIRIRNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMaDLENLSK 558
Cdd:COG4181    8 IIELRGLTKTVGTGAGELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFAL-DEDARAR 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   559 LTGvcpqSNVQFDF--------LTVRENLRL----------FAKIKGIL------------P--------QEV------- 593
Cdd:COG4181   87 LRA----RHVGFVFqsfqllptLTALENVMLplelagrrdaRARARALLervglghrldhyPaqlsggeqQRValarafa 162
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701   594 -DKEIFLLDEPTAGLDPFSRHQVWNLL----KERKTDRVILfsTQfmDEAdiLA---DRKVFLSQGKL 653
Cdd:COG4181  163 tEPAILFADEPTGNLDAATGEQIIDLLfelnRERGTTLVLV--TH--DPA--LAarcDRVLRLRAGRL 224
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
481-653 4.66e-13

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 70.84  E-value: 4.66e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   481 RIRNVTKEYKGkpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTiYNNKlsemadlenlsKLT 560
Cdd:COG0411    6 EVRGLTKRFGG----LVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRIL-FDGR-----------DIT 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   561 GVCP------------QsNVQ-FDFLTVRENLRL---------FAKIKGILPQEVDKE---------------------- 596
Cdd:COG0411   70 GLPPhriarlgiartfQ-NPRlFPELTVLENVLVaaharlgrgLLAALLRLPRARREEreareraeellervgladrade 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   597 ------------------------IFLLDEPTAGLDPFSRHQVWNLLKERKTDRVIlfsTQFMDEADI-----LADRKVF 647
Cdd:COG0411  149 pagnlsygqqrrleiaralatepkLLLLDEPAAGLNPEETEELAELIRRLRDERGI---TILLIEHDMdlvmgLADRIVV 225

                 ....*.
gi 6005701   648 LSQGKL 653
Cdd:COG0411  226 LDFGRV 231
cbiO PRK13644
energy-coupling factor transporter ATPase;
1265-1474 4.70e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 71.17  E-value: 4.70e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGD------------------ALEFLGYCPQ 1326
Cdd:PRK13644   17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDfsklqgirklvgivfqnpETQFVGRTVE 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1327 -------ENALWPNLTVRQHLEVYAAVKGLRKGdaevaitrlvdalklqdQLKSPvKTLSEGIKRKLCFVLSILGNPSVV 1399
Cdd:PRK13644   97 edlafgpENLCLPPIEIRKRVDRALAEIGLEKY-----------------RHRSP-KTLSGGQGQCVALAGILTMEPECL 158
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701   1400 LLDEPSTGMDPEGQQQMWQAIRatfRNTERGALL--TTHYMAEAEAVcDRVAIMVSGRLRCIGSIQHLKSKFGKDYL 1474
Cdd:PRK13644  159 IFDEVTSMLDPDSGIAVLERIK---KLHEKGKTIvyITHNLEELHDA-DRIIVMDRGKIVLEGEPENVLSDVSLQTL 231
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
504-658 5.04e-13

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 72.44  E-value: 5.04e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   504 FDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLS----KLtGVCPQSNVQFDFLTVRENL 579
Cdd:COG4148   20 FTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQDSARGIFLPphrrRI-GYVFQEARLFPHLSVRGNL 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   580 -----RLFAKIKGILPQEV---------------------------------DKEIFLLDEPTAGLDPFSRHQVWNLLkE 621
Cdd:COG4148   99 lygrkRAPRAERRISFDEVvellgighlldrrpatlsggerqrvaigrallsSPRLLLMDEPLAALDLARKAEILPYL-E 177
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 6005701   622 RKTDRV---ILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:COG4148  178 RLRDELdipILYVSHSLDEVARLADHVVLLEQGRVVASGP 217
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
466-609 5.27e-13

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 73.55  E-value: 5.27e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     466 SFEQAPPEFQGKEAIRIRNVTKEYKGKPdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNN 545
Cdd:TIGR02868  321 SAPAAGAVGLGKPTLELRDLSAGYPGAP---PVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGV 397
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     546 KLSEmADLENLSKLTGVCPQSNVQFDfLTVRENLRL-------------FAKIK-GILPQEV------------------ 593
Cdd:TIGR02868  398 PVSS-LDQDEVRRRVSVCAQDAHLFD-TTVRENLRLarpdatdeelwaaLERVGlADWLRALpdgldtvlgeggarlsgg 475
                          170       180
                   ....*....|....*....|....*....
gi 6005701     594 -------------DKEIFLLDEPTAGLDP 609
Cdd:TIGR02868  476 erqrlalarallaDAPILLLDEPTEHLDA 504
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
1268-1421 6.23e-13

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 69.19  E-value: 6.23e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITG--DTKPTAGQVLLKGSGGGDALE-FLGYCPQENALWPNLTVRQHLEVYA 1344
Cdd:cd03232   25 NISGYVKPGTLTALMGESGAGKTTLLDVLAGrkTAGVITGEILINGRPLDKNFQrSTGYVEQQDVHSPNLTVREALRFSA 104
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701  1345 AVKGLrkgdaevaitrlvdalklqdqlkspvkTLSEgiKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIR 1421
Cdd:cd03232  105 LLRGL---------------------------SVEQ--RKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVRFLK 152
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
479-639 7.75e-13

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 73.62  E-value: 7.75e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYKgkpdKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNnklsemADLENLSK 558
Cdd:NF033858    1 VARLEGVSHRYG----KTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLG------GDMADARH 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    559 LTGVCPQ---------SNVQFDfLTVRENL----RLF--------AKIK------GILP--------------QEV---- 593
Cdd:NF033858   71 RRAVCPRiaympqglgKNLYPT-LSVFENLdffgRLFgqdaaerrRRIDellratGLAPfadrpagklsggmkQKLglcc 149
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 6005701    594 ----DKEIFLLDEPTAGLDPFSRHQVWNLLKERKTDRV---ILFSTQFMDEAD 639
Cdd:NF033858  150 alihDPDLLILDEPTTGVDPLSRRQFWELIDRIRAERPgmsVLVATAYMEEAE 202
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
1271-1436 7.80e-13

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 69.49  E-value: 7.80e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1271 FCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG--SGGGDALEFLGYCPQENALWPNLTVRQHLEVYAAVKG 1348
Cdd:PRK13543   32 FHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGktATRGDRSRFMAYLGHLPGLKADLSTLENLHFLCGLHG 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1349 LRK----GDAeVAITRLVDalkLQDQLkspVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATF 1424
Cdd:PRK13543  112 RRAkqmpGSA-LAIVGLAG---YEDTL---VRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEGITLVNRMISAHL 184
                         170
                  ....*....|..
gi 6005701   1425 RnTERGALLTTH 1436
Cdd:PRK13543  185 R-GGGAALVTTH 195
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
1256-1468 7.81e-13

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 70.40  E-value: 7.81e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1256 CFSKRKN-KIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----SGGGDALEFLGYCPQEna 1329
Cdd:PRK13632   14 SFSYPNSeNNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGitiskENLKEIRKKIGIIFQN-- 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1330 lwPN-----LTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCfVLSILG-NPSVVLLDE 1403
Cdd:PRK13632   92 --PDnqfigATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVA-IASVLAlNPEIIIFDE 168
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701   1404 pSTGM-DPEGQQQMWQAIRATFRNTERGALLTTHYMAEAeAVCDRVAIMVSGRLRCIGSIQH-LKSK 1468
Cdd:PRK13632  169 -STSMlDPKGKREIKKIMVDLRKTRKKTLISITHDMDEA-ILADKVIVFSEGKLIAQGKPKEiLNNK 233
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
476-653 8.53e-13

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 68.23  E-value: 8.53e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   476 GKEAIRIRNVTKEYkgkpdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLEN 555
Cdd:cd03215    1 GEPVLEVRGLSVKG--------AVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDA 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   556 LS----------KLTGVCPQsnvqfdfLTVRENLRLFAKIKG------ILPQEV--DKEIFLLDEPTAGLDPFSRHQVWN 617
Cdd:cd03215   73 IRagiayvpedrKREGLVLD-------LSVAENIALSSLLSGgnqqkvVLARWLarDPRVLILDEPTRGVDVGAKAEIYR 145
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 6005701   618 LLKErKTDR---VILFSTQfMDEADILADRKVFLSQGKL 653
Cdd:cd03215  146 LIRE-LADAgkaVLLISSE-LDELLGLCDRILVMYEGRI 182
cbiO PRK13644
energy-coupling factor transporter ATPase;
480-658 8.74e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 70.40  E-value: 8.74e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYkgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLSKL 559
Cdd:PRK13644    2 IRLENVSYSY---PDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKLQGIRKL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    560 TGVCPQS-NVQFDFLTVRENL-------------------RLFAKIK-----------------------GILPQEVDKE 596
Cdd:PRK13644   79 VGIVFQNpETQFVGRTVEEDLafgpenlclppieirkrvdRALAEIGlekyrhrspktlsggqgqcvalaGILTMEPECL 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6005701    597 IFllDEPTAGLDPFSRHQVW-NLLKERKTDRVILFSTQFMDEADIlADRKVFLSQGKLKCAGS 658
Cdd:PRK13644  159 IF--DEVTSMLDPDSGIAVLeRIKKLHEKGKTIVYITHNLEELHD-ADRIIVMDRGKIVLEGE 218
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
453-654 9.80e-13

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 72.79  E-value: 9.80e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   453 LEDEMDADPSFHDSFEQAPPefQGKEAIRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGL 532
Cdd:COG0488  291 REEPPRRDKTVEIRFPPPER--LGKKVLELEGLSKSYGDKT----LLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGE 364
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   533 SVPTKGSVTIYnnklsemadlENLSklTGVCPQSNVQFDF-LTVRENLRLFA------KIKGIL------PQEVDKEI-- 597
Cdd:COG0488  365 LEPDSGTVKLG----------ETVK--IGYFDQHQEELDPdKTVLDELRDGApggteqEVRGYLgrflfsGDDAFKPVgv 432
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   598 --------------------FL-LDEPTAGLDPFSRHQVWNLLKERK-TdrVILFS--TQFMDEadiLADRKVFLSQGKL 653
Cdd:COG0488  433 lsggekarlalaklllsppnVLlLDEPTNHLDIETLEALEEALDDFPgT--VLLVShdRYFLDR---VATRILEFEDGGV 507

                 .
gi 6005701   654 K 654
Cdd:COG0488  508 R 508
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
470-653 9.85e-13

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 69.42  E-value: 9.85e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   470 APPEFQGKeaIRIRNVTKEYKGKPDKiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVtIYNNKLSE 549
Cdd:cd03248    4 APDHLKGI--VKFQNVTFAYPTRPDT-LVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQV-LLDGKPIS 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   550 MADLENLSKLTGVCPQSNVQFDfLTVRENLRL------FAKIKGI------------LPQEVDKE--------------- 596
Cdd:cd03248   80 QYEHKYLHSKVSLVGQEPVLFA-RSLQDNIAYglqscsFECVKEAaqkahahsfiseLASGYDTEvgekgsqlsggqkqr 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701   597 ------------IFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADiLADRKVFLSQGKL 653
Cdd:cd03248  159 vaiaralirnpqVLILDEATSALDAESEQQVQQALYDWPERRTVLVIAHRLSTVE-RADQILVLDGGRI 226
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
1247-1456 1.01e-12

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 69.13  E-value: 1.01e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1247 KEYAGKRKgcfskrknkiATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSG----GGDALEFL- 1321
Cdd:PRK10908    9 KAYLGGRQ----------ALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDitrlKNREVPFLr 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1322 ---GYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSV 1398
Cdd:PRK10908   79 rqiGMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAV 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   1399 VLLDEPSTGMDPEgqqqMWQAIRATFRNTER---GALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK10908  159 LLADEPTGNLDDA----LSEGILRLFEEFNRvgvTVLMATHDIGLISRRSYRMLTLSDGHL 215
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
1267-1461 1.02e-12

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 69.06  E-value: 1.02e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG---SGGG--DALEFLGYCPQEnalwPNL---TVRQ 1338
Cdd:cd03244   21 KNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGvdiSKIGlhDLRSRISIIPQD----PVLfsgTIRS 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1339 HL---------EVYAAVKglrkgdaEVAITRLVDAL--KLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTG 1407
Cdd:cd03244   97 NLdpfgeysdeELWQALE-------RVGLKEFVESLpgGLDTVVEEGGENLSVGQRQLLCLARALLRKSKILVLDEATAS 169
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701  1408 MDPEGQQQMWQAIRATFRNTergALLT-THYMaeaEAV--CDRVAIMVSGRLRCIGS 1461
Cdd:cd03244  170 VDPETDALIQKTIREAFKDC---TVLTiAHRL---DTIidSDRILVLDKGRVVEFDS 220
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
1235-1455 1.21e-12

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 69.57  E-value: 1.21e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1235 DEKPVIIASCLRKEYaGKRKGCfskrknkiatRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGG 1314
Cdd:PRK11701    2 MDQPLLSVRGLTKLY-GPRKGC----------RDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDG 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1315 GDA-LEFLGYcPQENAL----WPnlTVRQHlevyaAVKGLRKG---DAEVAiTRL-----------------------VD 1363
Cdd:PRK11701   71 QLRdLYALSE-AERRRLlrteWG--FVHQH-----PRDGLRMQvsaGGNIG-ERLmavgarhygdiratagdwlerveID 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1364 ALKLQDQlksPvKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEA 1443
Cdd:PRK11701  142 AARIDDL---P-TTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARL 217
                         250
                  ....*....|..
gi 6005701   1444 VCDRVAIMVSGR 1455
Cdd:PRK11701  218 LAHRLLVMKQGR 229
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
1269-1464 1.50e-12

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 71.87  E-value: 1.50e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1269 VSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----SGGGDALEF-LGYCPQ---ENALWPNLTVRQH 1339
Cdd:PRK11288  272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGkpidiRSPRDAIRAgIMLCPEdrkAEGIIPVHSVADN 351
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1340 LEVYAAVKGLRKG----------DAEVAITRLvdALKLQDQlKSPVKTLSEGIKRKlcfvlSILG-----NPSVVLLDEP 1404
Cdd:PRK11288  352 INISARRHHLRAGclinnrweaeNADRFIRSL--NIKTPSR-EQLIMNLSGGNQQK-----AILGrwlseDMKVILLDEP 423
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701   1405 STGMDPEGQQQMWQAIratFRNTERG--ALLTTHYMAEAEAVCDRVAIMVSGRLRciGSIQH 1464
Cdd:PRK11288  424 TRGIDVGAKHEIYNVI---YELAAQGvaVLFVSSDLPEVLGVADRIVVMREGRIA--GELAR 480
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
480-658 1.57e-12

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 69.27  E-value: 1.57e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLEnLSKL 559
Cdd:PRK11231    3 LRTENLTVGYGTKR----ILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQ-LARR 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    560 TGVCPQSNVQFDFLTVRE--------NLRLFAKIKG--------------------------------------ILPQev 593
Cdd:PRK11231   78 LALLPQHHLTPEGITVRElvaygrspWLSLWGRLSAednarvnqameqtrinhladrrltdlsggqrqraflamVLAQ-- 155
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701    594 DKEIFLLDEPTAGLDpfSRHQV--WNLLKER----KTDRVILFStqfMDEADILADRKVFLSQGKLKCAGS 658
Cdd:PRK11231  156 DTPVVLLDEPTTYLD--INHQVelMRLMRELntqgKTVVTVLHD---LNQASRYCDHLVVLANGHVMAQGT 221
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
480-672 2.10e-12

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 68.41  E-value: 2.10e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMaDLENLSKL 559
Cdd:cd03251    1 VEFKNVTFRYPG--DGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDY-TLASLRRQ 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFlTVRENLR-----------LFA--------------------------KIKGILPQEV--------D 594
Cdd:cd03251   78 IGLVSQDVFLFND-TVAENIAygrpgatreevEEAaraanahefimelpegydtvigergvKLSGGQRQRIaiarallkD 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   595 KEIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVIL-----FSTqFMDeadilADRKVFLSQGKLKCAGSSLFLKKKWGIG 669
Cdd:cd03251  157 PPILILDEATSALDTESERLVQAALERLMKNRTTFviahrLST-IEN-----ADRIVVLEDGKIVERGTHEELLAQGGVY 230

                 ...
gi 6005701   670 YHL 672
Cdd:cd03251  231 AKL 233
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
1265-1465 2.15e-12

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 69.27  E-value: 2.15e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsgGGDALEflgycpqENALWpnlTVRQHLE--- 1341
Cdd:PRK13635   22 ALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITV----GGMVLS-------EETVW---DVRRQVGmvf 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1342 -------VYAAVK-----GL--RKGDAEVAITRLVDALKL---QDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEP 1404
Cdd:PRK13635   88 qnpdnqfVGATVQddvafGLenIGVPREEMVERVDQALRQvgmEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEA 167
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   1405 STGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAeAVCDRVAIMVSGRLRCIGSIQHL 1465
Cdd:PRK13635  168 TSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEA-AQADRVIVMNKGEILEEGTPEEI 227
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
1267-1456 2.24e-12

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 68.30  E-value: 2.24e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG------SGGGDAL---EFLGYCPQENALWPNLTVR 1337
Cdd:PRK11629   26 HNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGqpmsklSSAAKAElrnQKLGFIYQFHHLLPDFTAL 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1338 QHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMW 1417
Cdd:PRK11629  106 ENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADSIF 185
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 6005701   1418 QAIRATFRNTERGALLTTHYMAEAEAVcDRVAIMVSGRL 1456
Cdd:PRK11629  186 QLLGELNRLQGTAFLVVTHDLQLAKRM-SRQLEMRDGRL 223
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
1267-1455 2.60e-12

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 67.67  E-value: 2.60e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGqvlLKGS---GGGDALEF-------LGYCPQENALWPNLTV 1336
Cdd:cd03233   24 KDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNVS---VEGDihyNGIPYKEFaekypgeIIYVSEEDVHFPTLTV 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1337 RQHLEVYAAVKGlrkgdaevaitrlvdalklqDQLkspVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQM 1416
Cdd:cd03233  101 RETLDFALRCKG--------------------NEF---VRGISGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTALEI 157
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 6005701  1417 WQAIRaTFRNTERGALLTTHYMA--EAEAVCDRVAIMVSGR 1455
Cdd:cd03233  158 LKCIR-TMADVLKTTTFVSLYQAsdEIYDLFDKVLVLYEGR 197
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
480-580 2.94e-12

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 68.03  E-value: 2.94e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKgkPDKiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMaDLENLSKL 559
Cdd:cd03253    1 IEFENVTFAYD--PGR-PVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREV-TLDSLRRA 76
                         90       100
                 ....*....|....*....|.
gi 6005701   560 TGVCPQSNVQFDfLTVRENLR 580
Cdd:cd03253   77 IGVVPQDTVLFN-DTIGYNIR 96
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
1268-1465 3.04e-12

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 70.13  E-value: 3.04e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGD-ALEFLGYCP--QENALWPNLTVRQHleVYA 1344
Cdd:PRK11432   24 NLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHrSIQQRDICMvfQSYALFPHMSLGEN--VGY 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1345 AVKGLRKGDAEVAiTRLVDALKLQDQL---KSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIR 1421
Cdd:PRK11432  102 GLKMLGVPKEERK-QRVKEALELVDLAgfeDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIR 180
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 6005701   1422 ATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHL 1465
Cdd:PRK11432  181 ELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQEL 224
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
480-657 3.21e-12

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 68.13  E-value: 3.21e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKpdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVtiynnkLSEMADLENLS-- 557
Cdd:cd03299    1 LKVENLSKDWKEF-----KLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKI------LLNGKDITNLPpe 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   558 -KLTGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDK----------------------------------------E 596
Cdd:cd03299   70 kRDISYVPQNYALFPHMTVYKNIAYGLKKRKVDKKEIERkvleiaemlgidhllnrkpetlsggeqqrvaiaralvvnpK 149
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6005701   597 IFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAG 657
Cdd:cd03299  150 ILLLDEPFSALDVRTKEKLREELKKirKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVG 212
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
1269-1409 3.32e-12

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 68.42  E-value: 3.32e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1269 VSFCVRKGEVLGLLGHNGAGKSTSIKVITGdTKPTAGQVLLkgsgGGDALEFL---------GYCPQENALWPNLTVRQH 1339
Cdd:PRK03695   15 LSAEVRAGEILHLVGPNGAGKSTLLARMAG-LLPGSGSIQF----AGQPLEAWsaaelarhrAYLSQQQTPPFAMPVFQY 89
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701   1340 LEVYAAVkGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSIL-----GNPS--VVLLDEPSTGMD 1409
Cdd:PRK03695   90 LTLHQPD-KTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLqvwpdINPAgqLLLLDEPMNSLD 165
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
467-653 4.00e-12

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 70.60  E-value: 4.00e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     467 FEQAPPEFQGKEAIRIRNVTKEY----KGKpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI 542
Cdd:TIGR03269  267 VEKECEVEVGEPIIKVRNVSKRYisvdRGV---VKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNV 343
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     543 -YNNKLSEMADLENL-----SKLTGVCPQSNVQFDFLTVRENL---------RLFAKIKGI------------------- 588
Cdd:TIGR03269  344 rVGDEWVDMTKPGPDgrgraKRYIGILHQEYDLYPHRTVLDNLteaiglelpDELARMKAVitlkmvgfdeekaeeildk 423
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     589 --------------LPQEVDKE--IFLLDEPTAGLDPFSRHQVWN-LLKERKT-DRVILFSTQFMDEADILADRKVFLSQ 650
Cdd:TIGR03269  424 ypdelsegerhrvaLAQVLIKEprIVILDEPTGTMDPITKVDVTHsILKAREEmEQTFIIVSHDMDFVLDVCDRAALMRD 503

                   ...
gi 6005701     651 GKL 653
Cdd:TIGR03269  504 GKI 506
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
479-653 4.31e-12

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 67.73  E-value: 4.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYKGKpdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNK--LSEMADLENL 556
Cdd:PRK11124    2 SIQLNGINCFYGAH----QALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHfdFSKTPSDKAI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    557 SKLtgvcpQSNVQFDF--------LTVRENL------------------------RL----FA-----KIKGILPQEV-- 593
Cdd:PRK11124   78 REL-----RRNVGMVFqqynlwphLTVQQNLieapcrvlglskdqalaraeklleRLrlkpYAdrfplHLSGGQQQRVai 152
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701    594 ------DKEIFLLDEPTAGLDPFSRHQVWNLLKE-RKT--DRVILfsTQFMDEADILADRKVFLSQGKL 653
Cdd:PRK11124  153 aralmmEPQVLLFDEPTAALDPEITAQIVSIIRElAETgiTQVIV--THEVEVARKTASRVVYMENGHI 219
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
1273-1452 4.39e-12

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 70.97  E-value: 4.39e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1273 VRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSgggdalefLGYCPQEnalwpnLTVRQHLEVYAAVKGLRKG 1352
Cdd:COG1245  363 IREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLK--------ISYKPQY------ISPDYDGTVEEFLRSANTD 428
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1353 DAEVAI--TRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERG 1430
Cdd:COG1245  429 DFGSSYykTEIIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAENRGKT 508
                        170       180
                 ....*....|....*....|..
gi 6005701  1431 ALLTTHYMAEAEAVCDRvaIMV 1452
Cdd:COG1245  509 AMVVDHDIYLIDYISDR--LMV 528
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
1267-1436 4.56e-12

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 66.90  E-value: 4.56e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDAL----EFLGYCPQENALWPNLTVRQHlev 1342
Cdd:PRK13540   18 QQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKDLctyqKQLCFVGHRSGINPYLTLREN--- 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1343 yaAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRA 1422
Cdd:PRK13540   95 --CLYDIHFSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIITKIQE 172
                         170
                  ....*....|....
gi 6005701   1423 tFRNTERGALLTTH 1436
Cdd:PRK13540  173 -HRAKGGAVLLTSH 185
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
1263-1455 4.60e-12

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 68.19  E-value: 4.60e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1263 KIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGsgggdalEFLGYCPQEN-ALW---------- 1331
Cdd:COG1101   19 KRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDG-------KDVTKLPEYKrAKYigrvfqdpmm 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1332 ---PNLTVRQHLEVyAAVKGLRKG------DAEVAITRlvDALK-----LQDQLKSPVKTLSEGIKRKLCFVLSILGNPS 1397
Cdd:COG1101   92 gtaPSMTIEENLAL-AYRRGKRRGlrrgltKKRRELFR--ELLAtlglgLENRLDTKVGLLSGGQRQALSLLMATLTKPK 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701  1398 VVLLDEPSTGMDPEGQQQMwqaIRATFRNTERG---ALLTTHYMAEAEAVCDRVAIMVSGR 1455
Cdd:COG1101  169 LLLLDEHTAALDPKTAALV---LELTEKIVEENnltTLMVTHNMEQALDYGNRLIMMHEGR 226
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
475-658 6.36e-12

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 69.21  E-value: 6.36e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    475 QGKEAIRIRNVTKEYKGKpdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIynnklsemadle 554
Cdd:PRK09452   10 SLSPLVELRGISKSFDGK----EVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIML------------ 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    555 NLSKLTGVCP---------QSNVQFDFLTVREN----LRL----FAKIK------------------------------- 586
Cdd:PRK09452   74 DGQDITHVPAenrhvntvfQSYALFPHMTVFENvafgLRMqktpAAEITprvmealrmvqleefaqrkphqlsggqqqrv 153
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701    587 GILPQEVDK-EIFLLDEPTAGLDPFSRHQVWNLLK--ERKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:PRK09452  154 AIARAVVNKpKVLLLDESLSALDYKLRKQMQNELKalQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGT 228
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
479-542 7.12e-12

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 69.67  E-value: 7.12e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701   479 AIRIRNVTKEYKGkpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI 542
Cdd:COG3845    5 ALELRGITKRFGG----VVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILI 64
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
1267-1436 7.43e-12

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 64.39  E-value: 7.43e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsggGDALEFlGYCPQenalwpnltvrqhlevyaav 1346
Cdd:cd03221   17 KDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTW-----GSTVKI-GYFEQ-------------------- 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1347 kglrkgdaevaitrlvdalklqdqlkspvktLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQqqmwQAIRATFRN 1426
Cdd:cd03221   71 -------------------------------LSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLESI----EALEEALKE 115
                        170
                 ....*....|
gi 6005701  1427 TERGALLTTH 1436
Cdd:cd03221  116 YPGTVILVSH 125
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
1278-1461 7.64e-12

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 67.72  E-value: 7.64e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1278 VLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGsgggDALEFlgycpQENALwpnLTVRQHLEV----------YAAVK 1347
Cdd:PRK13638   29 VTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQG----KPLDY-----SKRGL---LALRQQVATvfqdpeqqifYTDID 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1348 G-----LRK-GDAEVAITRLVD-ALKLQDQL---KSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMW 1417
Cdd:PRK13638   97 SdiafsLRNlGVPEAEITRRVDeALTLVDAQhfrHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMI 176
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 6005701   1418 QAIRATFRNTERgALLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:PRK13638  177 AIIRRIVAQGNH-VIISSHDIDLIYEISDAVYVLRQGQILTHGA 219
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
1260-1454 7.99e-12

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 67.60  E-value: 7.99e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1260 RKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALE--FLGYCPQ-ENALWPNLTV 1336
Cdd:PRK15056   17 RNGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQknLVAYVPQsEEVDWSFPVL 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1337 RQHLEV---YAAVKGLRKGDA------EVAITRlVDALKLQDQlksPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTG 1407
Cdd:PRK15056   97 VEDVVMmgrYGHMGWLRRAKKrdrqivTAALAR-VDMVEFRHR---QIGELSGGQKKRVFLARAIAQQGQVILLDEPFTG 172
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 6005701   1408 MDPEGQQQMWQAIRaTFRNTERGALLTTHYMAEAEAVCDrVAIMVSG 1454
Cdd:PRK15056  173 VDVKTEARIISLLR-ELRDEGKTMLVSTHNLGSVTEFCD-YTVMVKG 217
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
470-658 8.27e-12

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 68.34  E-value: 8.27e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    470 APPEFQGKEAIRIRNVTKEYKGK-PDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVT---IYNN 545
Cdd:PRK13631   12 VPNPLSDDIILRVKNLYCVFDEKqENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQvgdIYIG 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    546 ------------KLSEMADLENLSKLTGVCPQ--------SNVQFDFL-------TVRENLRLFAK-------------- 584
Cdd:PRK13631   92 dkknnhelitnpYSKKIKNFKELRRRVSMVFQfpeyqlfkDTIEKDIMfgpvalgVKKSEAKKLAKfylnkmglddsyle 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    585 ---------------IKGILPqeVDKEIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFL 648
Cdd:PRK13631  172 rspfglsggqkrrvaIAGILA--IQPEILIFDEPTAGLDPKGEHEMMQLILDaKANNKTVFVITHTMEHVLEVADEVIVM 249
                         250
                  ....*....|
gi 6005701    649 SQGKLKCAGS 658
Cdd:PRK13631  250 DKGKILKTGT 259
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
457-672 8.28e-12

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 70.14  E-value: 8.28e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     457 MDADPSFHDSFEQAPPEFQGKeaIRIRNVTKEYKGKPDKiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPT 536
Cdd:TIGR00958  458 LDRKPNIPLTGTLAPLNLEGL--IEFQDVSFSYPNRPDV-PVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPT 534
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     537 KGSVTIYNNKLSEMaDLENLSKLTGVCPQSNVQFDfLTVRENL------------RLFAKIKGI------LPQEVDKEI- 597
Cdd:TIGR00958  535 GGQVLLDGVPLVQY-DHHYLHRQVALVGQEPVLFS-GSVRENIaygltdtpdeeiMAAAKAANAhdfimeFPNGYDTEVg 612
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     598 --------------------------FLLDEPTAGLDPFSRHQVWNlLKERKtDRVILFSTQFMDEADiLADRKVFLSQG 651
Cdd:TIGR00958  613 ekgsqlsggqkqriaiaralvrkprvLILDEATSALDAECEQLLQE-SRSRA-SRTVLLIAHRLSTVE-RADQILVLKKG 689
                          250       260
                   ....*....|....*....|.
gi 6005701     652 KLKCAGSSLFLKKKWGIGYHL 672
Cdd:TIGR00958  690 SVVEMGTHKQLMEDQGCYKHL 710
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
1267-1456 9.25e-12

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 69.65  E-value: 9.25e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG------------SGG---------GDALeFLGYCP 1325
Cdd:PRK10762  269 NDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGhevvtrspqdglANGivyisedrkRDGL-VLGMSV 347
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1326 QENAlwpNLTVRQHLEvYAAVKgLRKGDAEVAITRLVDALKL----QDQlksPVKTLSEGIKRKLCFVLSILGNPSVVLL 1401
Cdd:PRK10762  348 KENM---SLTALRYFS-RAGGS-LKHADEQQAVSDFIRLFNIktpsMEQ---AIGLLSGGNQQKVAIARGLMTRPKVLIL 419
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 6005701   1402 DEPSTGMDPEGQQQMWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK10762  420 DEPTRGVDVGAKKEIYQLIN-QFKAEGLSIILVSSEMPEVLGMSDRILVMHEGRI 473
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
480-652 1.09e-11

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 68.71  E-value: 1.09e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLEnlsKL 559
Cdd:PRK11607   20 LEIRNLTKSFDGQH----AVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQ---RP 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    560 TGVCPQSNVQFDFLTVRENL-------RL--------------------FAKIK-----GILPQEV--------DKEIFL 599
Cdd:PRK11607   93 INMMFQSYALFPHMTVEQNIafglkqdKLpkaeiasrvnemlglvhmqeFAKRKphqlsGGQRQRValarslakRPKLLL 172
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701    600 LDEPTAGLDPFSR----HQVWNLLKERKTDRVILFSTQfmDEADILADRKVFLSQGK 652
Cdd:PRK11607  173 LDEPMGALDKKLRdrmqLEVVDILERVGVTCVMVTHDQ--EEAMTMAGRIAIMNRGK 227
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
1273-1452 1.17e-11

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 69.45  E-value: 1.17e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1273 VRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL--LKGSgggdaleflgYCPQENALWPNLTVRQHLEvyAAVKGLr 1350
Cdd:PRK13409  362 IYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDpeLKIS----------YKPQYIKPDYDGTVEDLLR--SITDDL- 428
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1351 kgDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERG 1430
Cdd:PRK13409  429 --GSSYYKSEIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEEREAT 506
                         170       180
                  ....*....|....*....|..
gi 6005701   1431 ALLTTHYMAEAEAVCDRvaIMV 1452
Cdd:PRK13409  507 ALVVDHDIYMIDYISDR--LMV 526
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
1260-1456 1.26e-11

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 68.90  E-value: 1.26e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1260 RKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS--GGGDALEF----LGYCPQE---NAL 1330
Cdd:COG3845  268 DRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEdiTGLSPRERrrlgVAYIPEDrlgRGL 347
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1331 WPNLTVRQHL-----EVYAAVKG--LRKGDAEVAITRLVDALKLQ-DQLKSPVKTLSEGIKRKlcFVLS--ILGNPSVVL 1400
Cdd:COG3845  348 VPDMSVAENLilgryRRPPFSRGgfLDRKAIRAFAEELIEEFDVRtPGPDTPARSLSGGNQQK--VILAreLSRDPKLLI 425
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701  1401 LDEPSTGMDPEGQQQMWQAIRATfRNteRGA--LLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:COG3845  426 AAQPTRGLDVGAIEFIHQRLLEL-RD--AGAavLLISEDLDEILALSDRIAVMYEGRI 480
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
479-658 1.26e-11

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 69.08  E-value: 1.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYKGKPDKieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADlENLSK 558
Cdd:PRK11160  338 SLTLNNVSFTYPDQPQP--VLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSE-AALRQ 414
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    559 LTGVCPQSnVQFDFLTVRENLRLFA------KIKGILpQEV--------------------------------------- 593
Cdd:PRK11160  415 AISVVSQR-VHLFSATLRDNLLLAApnasdeALIEVL-QQVgleklleddkglnawlgeggrqlsggeqrrlgiarallh 492
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701    594 DKEIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFST-------QFmdeadilaDRKVFLSQGKLKCAGS 658
Cdd:PRK11160  493 DAPLLLLDEPTEGLDAETERQILELLAEHAQNKTVLMIThrltgleQF--------DRICVMDNGQIIEQGT 556
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
499-608 1.33e-11

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 65.67  E-value: 1.33e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    499 LKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTiYNNKLSEMADLENLSKLTGvcpQSNVQFDFLTVREN 578
Cdd:PRK13539   18 FSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIK-LDGGDIDDPDVAEACHYLG---HRNAMKPALTVAEN 93
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701    579 LRLFAKIKGILPQEVD------------------------------------KEIFLLDEPTAGLD 608
Cdd:PRK13539   94 LEFWAAFLGGEELDIAaaleavglaplahlpfgylsagqkrrvalarllvsnRPIWILDEPTAALD 159
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
479-651 1.37e-11

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 66.65  E-value: 1.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLS-EMADLENLS 557
Cdd:PRK11248    1 MLQISHLYADYGGKP----ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEgPGAERGVVF 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    558 KLTGVCP----QSNVQFDF-----------LTVRENL----------RLFAKIKGILPQEV--------DKEIFLLDEPT 604
Cdd:PRK11248   77 QNEGLLPwrnvQDNVAFGLqlagvekmqrlEIAHQMLkkvglegaekRYIWQLSGGQRQRVgiaralaaNPQLLLLDEPF 156
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 6005701    605 AGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQG 651
Cdd:PRK11248  157 GALDAFTREQMQTLLLKlwQETGKQVLLITHDIEEAVFMATELVLLSPG 205
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
504-653 1.47e-11

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 66.14  E-value: 1.47e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    504 FDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLEN-LSKLTgvcpQSNVQFDFLTVREN---- 578
Cdd:PRK10771   20 LTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSRRpVSMLF----QENNLFSHLTVAQNiglg 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    579 ----LRLFAKIK----------GI------LPQEV----------------DKEIFLLDEPTAGLDPFSRHQVWNLLKER 622
Cdd:PRK10771   96 lnpgLKLNAAQReklhaiarqmGIedllarLPGQLsggqrqrvalarclvrEQPILLLDEPFSALDPALRQEMLTLVSQV 175
                         170       180       190
                  ....*....|....*....|....*....|...
gi 6005701    623 KTDRVI--LFSTQFMDEADILADRKVFLSQGKL 653
Cdd:PRK10771  176 CQERQLtlLMVSHSLEDAARIAPRSLVVADGRI 208
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
480-692 1.54e-11

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 68.68  E-value: 1.54e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     480 IRIRNVTKEYKGKpdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLS--VPTKGSVtIYNNKLSEMAD-LENL 556
Cdd:TIGR03269    1 IEVKNLTKKFDGK----EVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDqyEPTSGRI-IYHVALCEKCGyVERP 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     557 SKLTGVCPQSNVQF-----DFL----TVRENL---------RLFA----------------------------------- 583
Cdd:TIGR03269   76 SKVGEPCPVCGGTLepeevDFWnlsdKLRRRIrkriaimlqRTFAlygddtvldnvlealeeigyegkeavgravdliem 155
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     584 ------------------KIKGILPQEVDKE--IFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADIL 641
Cdd:TIGR03269  156 vqlshrithiardlsggeKQRVVLARQLAKEpfLFLADEPTGTLDPQTAKLVHNALEEavKASGISMVLTSHWPEVIEDL 235
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 6005701     642 ADRKVFLSQGKLKCAGSSLFLKKKWGIGYHLSLQLNEICVEENITSL--VKQH 692
Cdd:TIGR03269  236 SDKAIWLENGEIKEEGTPDEVVAVFMEGVSEVEKECEVEVGEPIIKVrnVSKR 288
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
480-661 1.55e-11

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 66.06  E-value: 1.55e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYkgkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLSKL 559
Cdd:PRK11614    6 LSFDKVSAHY----GKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKIMREA 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    560 TGVCPQSNVQFDFLTVRENLRL---FA----------KIKGILPQEVDKEI--------------------------FLL 600
Cdd:PRK11614   82 VAIVPEGRRVFSRMTVEENLAMggfFAerdqfqerikWVYELFPRLHERRIqragtmsggeqqmlaigralmsqprlLLL 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701    601 DEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGK--LKCAGSSLF 661
Cdd:PRK11614  162 DEPSLGLAPIIIQQIFDTIEQlREQGMTIFLVEQNANQALKLADRGYVLENGHvvLEDTGDALL 225
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
1265-1465 1.61e-11

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 69.11  E-value: 1.61e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQV-----------------------LLKGSGGGD-ALEF 1320
Cdd:PRK10261   31 AVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVqcdkmllrrrsrqvielseqsaaQMRHVRGADmAMIF 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1321 lgycpQE--NALWPNLTV-RQHLEVYAAVKGLRKGDAEVAITRLVDALKL---QDQLKSPVKTLSEGIKRKLCFVLSILG 1394
Cdd:PRK10261  111 -----QEpmTSLNPVFTVgEQIAESIRLHQGASREEAMVEAKRMLDQVRIpeaQTILSRYPHQLSGGMRQRVMIAMALSC 185
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   1395 NPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHL 1465
Cdd:PRK10261  186 RPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQI 256
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
481-644 2.11e-11

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 68.40  E-value: 2.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    481 RIRNVTKEYKGkpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI------YNNK-------- 546
Cdd:PRK11288    6 SFDGIGKTFPG----VKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIdgqemrFASTtaalaagv 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    547 ---------LSEMADLENLskLTGVCPQSnvqFDFL-------TVRENL-RLFAKIKGILP---------QEV------- 593
Cdd:PRK11288   82 aiiyqelhlVPEMTVAENL--YLGQLPHK---GGIVnrrllnyEAREQLeHLGVDIDPDTPlkylsigqrQMVeiakala 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 6005701    594 -DKEIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADR 644
Cdd:PRK11288  157 rNARVIAFDEPTSSLSAREIEQLFRVIRElRAEGRVILYVSHRMEEIFALCDA 209
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
479-653 2.41e-11

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 65.93  E-value: 2.41e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYKGKpdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI------YNNKLSEMAD 552
Cdd:PRK11264    3 AIEVKNLVKKFHGQ----TVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVgditidTARSLSQQKG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    553 L-ENLSKLTGVCPQSNVQFDFLTVRENL--------------------RLFAKI-------------KGILPQEV----- 593
Cdd:PRK11264   79 LiRQLRQHVGFVFQNFNLFPHRTVLENIiegpvivkgepkeeatararELLAKVglagketsyprrlSGGQQQRVaiara 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701    594 ---DKEIFLLDEPTAGLDPFSRHQVWNL---LKERKTDRVILfsTQFMDEADILADRKVFLSQGKL 653
Cdd:PRK11264  159 lamRPEVILFDEPTSALDPELVGEVLNTirqLAQEKRTMVIV--THEMSFARDVADRAIFMDQGRI 222
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
1273-1456 3.39e-11

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 65.16  E-value: 3.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1273 VRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLL--------KGSGGGDAL-----EFLGYCPQENALWPNLTVRQH 1339
Cdd:PRK11264   26 VKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVgditidtaRSLSQQKGLirqlrQHVGFVFQNFNLFPHRTVLEN 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1340 -LEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQ 1418
Cdd:PRK11264  106 iIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRPEVILFDEPTSALDPELVGEVLN 185
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 6005701   1419 AIRAtFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK11264  186 TIRQ-LAQEKRTMVIVTHEMSFARDVADRAIFMDQGRI 222
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
1256-1470 3.83e-11

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 64.94  E-value: 3.83e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1256 CFSKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsGGGD----ALEFL----GYCPQE 1327
Cdd:cd03253    7 TFAYDPGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILI---DGQDirevTLDSLrraiGVVPQD 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1328 NALWpNLTVRQHL----------EVYAAVKglrKGDAEVAITRLVDA---------LKlqdqlkspvktLSEGIKRKLCF 1388
Cdd:cd03253   84 TVLF-NDTIGYNIrygrpdatdeEVIEAAK---AAQIHDKIMRFPDGydtivgergLK-----------LSGGEKQRVAI 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1389 VLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNteRGALLTTHYMAEAeAVCDRVAIMVSGRLRCIGSIQHLKSK 1468
Cdd:cd03253  149 ARAILKNPPILLLDEATSALDTHTEREIQAALRDVSKG--RTTIVIAHRLSTI-VNADKIIVLKDGRIVERGTHEELLAK 225

                 ..
gi 6005701  1469 FG 1470
Cdd:cd03253  226 GG 227
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
1267-1411 5.00e-11

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 67.22  E-value: 5.00e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVllKGSGGGDalefLGYCPQENALW--PNLTVRQHLEVYA 1344
Cdd:PRK15064  336 KNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV--KWSENAN----IGYYAQDHAYDfeNDLTLFDWMSQWR 409
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   1345 avkglRKGDAEVAIT----RLvdaLKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPE 1411
Cdd:PRK15064  410 -----QEGDDEQAVRgtlgRL---LFSQDDIKKSVKVLSGGEKGRMLFGKLMMQKPNVLVMDEPTNHMDME 472
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
1235-1311 5.10e-11

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 65.91  E-value: 5.10e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701  1235 DEKPVIIASCLRKEYAgKRKGCFSKRKNKI-ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG 1311
Cdd:COG4608    3 MAEPLLEVRDLKKHFP-VRGGLFGRTVGVVkAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDG 79
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
480-671 5.96e-11

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 66.21  E-value: 5.96e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYkgkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKlseMADLENLSKL 559
Cdd:PRK11000    4 VTLRNVTKAY----GDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKR---MNDVPPAERG 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    560 TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDK----------------------------------------EIFL 599
Cdd:PRK11000   77 VGMVFQSYALYPHLSVAENMSFGLKLAGAKKEEINQrvnqvaevlqlahlldrkpkalsggqrqrvaigrtlvaepSVFL 156
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701    600 LDEPTAGLDPFSRHQVWNLLKE--RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGSSLFLkkkwgigYH 671
Cdd:PRK11000  157 LDEPLSNLDAALRVQMRIEISRlhKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLEL-------YH 223
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
1267-1456 6.62e-11

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 64.34  E-value: 6.62e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKP----TAGQVLLKG------SGGGDALEFLGYCPQeNALWPNLTV 1336
Cdd:PRK10418   20 HGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAgvrqTAGRVLLDGkpvapcALRGRKIATIMQNPR-SAFNPLHTM 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1337 RQHLEVYAAVKGLRKGDAevAITRLVDALKLQDQ---LKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQ 1413
Cdd:PRK10418   99 HTHARETCLALGKPADDA--TLTAALEAVGLENAarvLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDLDVVAQ 176
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 6005701   1414 QQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK10418  177 ARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRI 219
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
1276-1465 6.78e-11

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 64.81  E-value: 6.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1276 GEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS--GGGDALEF---LGYCPQENALWPNLTVRQHLEV-----YAA 1345
Cdd:PRK10575   37 GKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQplESWSSKAFarkVAYLPQQLPAAEGMTVRELVAIgrypwHGA 116
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1346 VKGLRKGD---AEVAITrLVDALKLQDQLkspVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRA 1422
Cdd:PRK10575  117 LGRFGAADrekVEEAIS-LVGLKPLAHRL---VDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHR 192
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 6005701   1423 TFRntERGALLTT--HYMAEAEAVCDRVAIMVSGRLRCIGSIQHL 1465
Cdd:PRK10575  193 LSQ--ERGLTVIAvlHDINMAARYCDYLVALRGGEMIAQGTPAEL 235
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
1261-1469 6.80e-11

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 66.75  E-value: 6.80e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1261 KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITG--DTKPTAGQVLLKGS-----GGGDALEFLGY-CP------- 1325
Cdd:TIGR03269   11 DGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGmdQYEPTSGRIIYHVAlcekcGYVERPSKVGEpCPvcggtle 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1326 -QENALW-PNLTVRQHLEVYAAVKGLRK----GD-----------------AEVAITR---LVDALKLQDQLKSPVKTLS 1379
Cdd:TIGR03269   91 pEEVDFWnLSDKLRRRIRKRIAIMLQRTfalyGDdtvldnvlealeeigyeGKEAVGRavdLIEMVQLSHRITHIARDLS 170
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1380 EGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCI 1459
Cdd:TIGR03269  171 GGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDKAIWLENGEIKEE 250
                          250
                   ....*....|
gi 6005701    1460 GSIQHLKSKF 1469
Cdd:TIGR03269  251 GTPDEVVAVF 260
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
1242-1471 6.82e-11

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 64.71  E-value: 6.82e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1242 ASCLRKEYAGKrkGCFSKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS-----GGGD 1316
Cdd:PRK10419    6 VSGLSHHYAHG--GLSGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEplaklNRAQ 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1317 ALEF-----LGYCPQENALWPNLTVRQHL-EVYAAVKGLRKGDAEVAITRLVDALKLQDQL--KSPvKTLSEGIKRKLCF 1388
Cdd:PRK10419   84 RKAFrrdiqMVFQDSISAVNPRKTVREIIrEPLRHLLSLDKAERLARASEMLRAVDLDDSVldKRP-PQLSGGQLQRVCL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1389 VLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---RCIGSIQHL 1465
Cdd:PRK10419  163 ARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIvetQPVGDKLTF 242

                  ....*.
gi 6005701   1466 KSKFGK 1471
Cdd:PRK10419  243 SSPAGR 248
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
1267-1508 8.58e-11

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 64.49  E-value: 8.58e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITgDTKPTAGQVLLKG-SGGGDALE----FLGYCPQENALWPNlTVRQHLE 1341
Cdd:cd03289   21 ENISFSISPGQRVGLLGRTGSGKSTLLSAFL-RLLNTEGDIQIDGvSWNSVPLQkwrkAFGVIPQKVFIFSG-TFRKNLD 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1342 VYAAVKG--LRKGDAEVAITRLVDAL--KLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPegqqQMW 1417
Cdd:cd03289   99 PYGKWSDeeIWKVAEEVGLKSVIEQFpgQLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDP----ITY 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1418 QAIRATFRNTERGA--LLTTHYMaEAEAVCDRVAIMVSGRLRCIGSIQHLKSKfgkdyllemkvKNLAQVEPLHAEILRL 1495
Cdd:cd03289  175 QVIRKTLKQAFADCtvILSEHRI-EAMLECQRFLVIEENKVRQYDSIQKLLNE-----------KSHFKQAISPSDRLKL 242
                        250
                 ....*....|...
gi 6005701  1496 FPQAARQERYSSL 1508
Cdd:cd03289  243 FPRRNSSKSKRKP 255
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
504-638 9.52e-11

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 66.69  E-value: 9.52e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    504 FDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLsemaDLENLS--KLTGVCPQSnvqfdF-----LTVR 576
Cdd:NF033858  287 FRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPV----DAGDIAtrRRVGYMSQA-----FslygeLTVR 357
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    577 ENLRLFAKIKGILPQEVDK----------------------------------------EIFLLDEPTAGLDPFSRHQVW 616
Cdd:NF033858  358 QNLELHARLFHLPAAEIAArvaemlerfdladvadalpdslplgirqrlslavavihkpELLILDEPTSGVDPVARDMFW 437
                         170       180
                  ....*....|....*....|....*
gi 6005701    617 NLLKE--RKtDRVILF-STQFMDEA 638
Cdd:NF033858  438 RLLIElsRE-DGVTIFiSTHFMNEA 461
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
483-555 9.54e-11

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 63.68  E-value: 9.54e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701    483 RNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEM-----ADLEN 555
Cdd:PRK11629    9 DNLCKRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLssaakAELRN 86
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
1264-1409 1.29e-10

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 63.32  E-value: 1.29e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1264 IATR--NVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTkPTAGQVLLkgsgGGDALE---------FLGYCPQENALWP 1332
Cdd:COG4138    8 VAGRlgPISAQVNAGELIHLIGPNGAGKSTLLARMAGLL-PGQGEILL----NGRPLSdwsaaelarHRAYLSQQQSPPF 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1333 NLTVRQHLEVYAAvKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSIL-----GNPS--VVLLDEPS 1405
Cdd:COG4138   83 AMPVFQYLALHQP-AGASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLqvwptINPEgqLLLLDEPM 161

                 ....
gi 6005701  1406 TGMD 1409
Cdd:COG4138  162 NSLD 165
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
481-557 1.43e-10

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 63.41  E-value: 1.43e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701    481 RIRNVTKEYKGkpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVtIYNNKLSEMADLENLS 557
Cdd:PRK11701    8 SVRGLTKLYGP----RKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEV-HYRMRDGQLRDLYALS 79
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
479-658 1.47e-10

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 64.72  E-value: 1.47e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYkgkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLEnlsK 558
Cdd:PRK10851    2 SIEIANIKKSF----GRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARD---R 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    559 LTGVCPQSNVQFDFLTVRENL------------------------------------RLFAKIKGILPQEV--------D 594
Cdd:PRK10851   75 KVGFVFQHYALFRHMTVFDNIafgltvlprrerpnaaaikakvtqllemvqlahladRYPAQLSGGQKQRValaralavE 154
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701    595 KEIFLLDEPTAGLDPFSRHQV--W--NLLKERKTDRVilFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:PRK10851  155 PQILLLDEPFGALDAQVRKELrrWlrQLHEELKFTSV--FVTHDQEEAMEVADRVVVMSQGNIEQAGT 220
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
1270-1467 1.86e-10

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 62.68  E-value: 1.86e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1270 SFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDA--------LEFlgycpQENALWPNLTVRQH-- 1339
Cdd:PRK10771   19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTppsrrpvsMLF-----QENNLFSHLTVAQNig 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1340 ------LEVYAAVKGLRKGDAE-VAITRLVDALKLQdqlkspvktLSEGIKRKL----CFVLSilgNPsVVLLDEPSTGM 1408
Cdd:PRK10771   94 lglnpgLKLNAAQREKLHAIARqMGIEDLLARLPGQ---------LSGGQRQRValarCLVRE---QP-ILLLDEPFSAL 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701   1409 DPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKS 1467
Cdd:PRK10771  161 DPALRQEMLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDELLS 219
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
1278-1467 1.91e-10

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 63.58  E-value: 1.91e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1278 VLGLLGHNGAGKSTSIKVITGDTKPTAG-----QVLLKGSG---GGDALEF---LGYCPQENALWPnLTVRQHleVYAAV 1346
Cdd:PRK14271   49 VTSLMGPTGSGKTTFLRTLNRMNDKVSGyrysgDVLLGGRSifnYRDVLEFrrrVGMLFQRPNPFP-MSIMDN--VLAGV 125
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1347 KGLR-------KGDAEVAITR--LVDALKlqDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMW 1417
Cdd:PRK14271  126 RAHKlvprkefRGVAQARLTEvgLWDAVK--DRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIE 203
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 6005701   1418 QAIRATFRNTErgALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKS 1467
Cdd:PRK14271  204 EFIRSLADRLT--VIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFS 251
cbiO PRK13640
energy-coupling factor transporter ATPase;
479-658 2.42e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 63.28  E-value: 2.42e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYkgkPD-KIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVP---TKGSVTIYNNKLSEMADLE 554
Cdd:PRK13640    5 IVEFKHVSFTY---PDsKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPddnPNSKITVDGITLTAKTVWD 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    555 NLSKLTGVCPQSNVQFDFLTVR-------EN--------LRLFAK---------------------------IKGILPqe 592
Cdd:PRK13640   82 IREKVGIVFQNPDNQFVGATVGddvafglENravprpemIKIVRDvladvgmldyidsepanlsggqkqrvaIAGILA-- 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701    593 VDKEIFLLDEPTAGLDPFSRHQVWNLLKERKTDR-VILFS-TQFMDEADiLADRKVFLSQGKLKCAGS 658
Cdd:PRK13640  160 VEPKIIILDESTSMLDPAGKEQILKLIRKLKKKNnLTVISiTHDIDEAN-MADQVLVLDDGKLLAQGS 226
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
1265-1502 2.70e-10

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 62.83  E-value: 2.70e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGggdaleflgyCPQENALWpnltVRQHL---- 1340
Cdd:PRK13647   20 ALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGRE----------VNAENEKW----VRSKVglvf 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1341 -----EVYAAV-----------KGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEP 1404
Cdd:PRK13647   86 qdpddQVFSSTvwddvafgpvnMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEP 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1405 STGMDPEGQQQMwQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGsiqhlkskfGKDYLLEMKVKNLAQ 1484
Cdd:PRK13647  166 MAYLDPRGQETL-MEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEG---------DKSLLTDEDIVEQAG 235
                         250
                  ....*....|....*....
gi 6005701   1485 VE-PLHAEILRLFPQAARQ 1502
Cdd:PRK13647  236 LRlPLVAQIFEDLPELGQS 254
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
1239-1411 2.98e-10

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 64.96  E-value: 2.98e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1239 VIIASCLRKEYAGKrkgcfskrknkIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsggGDAL 1318
Cdd:TIGR03719  322 VIEAENLTKAFGDK-----------LLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-----GETV 385
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1319 EfLGYCPQE-NALWPNLTVRQhlEVYAAVKGLRKGDAEVAITRLVDA--LKLQDQLKsPVKTLSEGIKRKLCFVLSILGN 1395
Cdd:TIGR03719  386 K-LAYVDQSrDALDPNKTVWE--EISGGLDIIKLGKREIPSRAYVGRfnFKGSDQQK-KVGQLSGGERNRVHLAKTLKSG 461
                          170
                   ....*....|....*.
gi 6005701    1396 PSVVLLDEPSTGMDPE 1411
Cdd:TIGR03719  462 GNVLLLDEPTNDLDVE 477
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
1265-1456 3.52e-10

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 62.20  E-value: 3.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGD------ALEFLGYCPQENALWPNLTVRQ 1338
Cdd:PRK11614   20 ALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDwqtakiMREAVAIVPEGRRVFSRMTVEE 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1339 HLevyaAVKGL--RKGDAEVAITRLVDAL-KLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQ 1415
Cdd:PRK11614  100 NL----AMGGFfaERDQFQERIKWVYELFpRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPIIIQQ 175
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 6005701   1416 MWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK11614  176 IFDTIE-QLREQGMTIFLVEQNANQALKLADRGYVLENGHV 215
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
1245-1441 3.66e-10

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 62.41  E-value: 3.66e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1245 LRKEYAGKRkgcfskrknkiATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLL-----KGSGGGDALE 1319
Cdd:PRK11248    7 LYADYGGKP-----------ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLdgkpvEGPGAERGVV 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1320 FlgycpQENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVV 1399
Cdd:PRK11248   76 F-----QNEGLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLL 150
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 6005701   1400 LLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEA 1441
Cdd:PRK11248  151 LLDEPFGALDAFTREQMQTLLLKLWQETGKQVLLITHDIEEA 192
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
480-653 3.87e-10

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 62.80  E-value: 3.87e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEY-KGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVT-IYNN-------KLSEM 550
Cdd:PRK13651    3 IKVKNIVKIFnKKLPTELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEwIFKDeknkkktKEKEK 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    551 ADLENLSKLT---------GVCPQSNVQFDF----------------------LTVRENLRLFAK--------------- 584
Cdd:PRK13651   83 VLEKLVIQKTrfkkikkikEIRRRVGVVFQFaeyqlfeqtiekdiifgpvsmgVSKEEAKKRAAKyielvgldesylqrs 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    585 -------------IKGILPQEVDkeIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQ 650
Cdd:PRK13651  163 pfelsggqkrrvaLAGILAMEPD--FLVFDEPTAGLDPQGVKEILEIFDNlNKQGKTIILVTHDLDNVLEWTKRTIFFKD 240

                  ...
gi 6005701    651 GKL 653
Cdd:PRK13651  241 GKI 243
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
489-648 4.21e-10

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 60.71  E-value: 4.21e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    489 YKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI-------YNNKLSEMAD--------- 552
Cdd:NF040873    2 YGGRP----VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRaggarvaYVPQRSEVPDslpltvrdl 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    553 --------LENLSKLT--------------GVCPQSNVQFDFLTVRENLR-LFAKIkgiLPQEVDkeIFLLDEPTAGLDP 609
Cdd:NF040873   78 vamgrwarRGLWRRLTrddraavddalervGLADLAGRQLGELSGGQRQRaLLAQG---LAQEAD--LLLLDEPTTGLDA 152
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 6005701    610 FSRHQVWNLLKE-RKTDRVILFSTQFMDEAdILADRKVFL 648
Cdd:NF040873  153 ESRERIIALLAEeHARGATVVVVTHDLELV-RRADPCVLL 191
cbiO PRK13643
energy-coupling factor transporter ATPase;
1268-1461 4.98e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 62.44  E-value: 4.98e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsggGDAL--------------EFLGYCPQ--ENALW 1331
Cdd:PRK13643   24 DIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTV-----GDIVvsstskqkeikpvrKKVGVVFQfpESQLF 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1332 PNlTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQL--KSPVKtLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMD 1409
Cdd:PRK13643   99 EE-TVLKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLADEFweKSPFE-LSGGQMRRVAIAGILAMEPEVLVLDEPTAGLD 176
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 6005701   1410 PEGQQQMWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:PRK13643  177 PKARIEMMQLFE-SIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGT 227
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
1267-1456 7.26e-10

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 61.47  E-value: 7.26e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITG--DTKPTA---GQVLLKGSG--GGDALEF---LGYCPQENALWPNLTV 1336
Cdd:PRK14247   20 DGVNLEIPDNTITALMGPSGSGKSTLLRVFNRliELYPEArvsGEVYLDGQDifKMDVIELrrrVQMVFQIPNPIPNLSI 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1337 RQHLEVYAAVKGLRKGDAEVAiTRLVDALK-------LQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMD 1409
Cdd:PRK14247  100 FENVALGLKLNRLVKSKKELQ-ERVRWALEkaqlwdeVKDRLDAPAGKLSGGQQQRLCIARALAFQPEVLLADEPTANLD 178
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 6005701   1410 PEGQQQmwqaIRATF--RNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK14247  179 PENTAK----IESLFleLKKDMTIVLVTHFPQQAARISDYVAFLYKGQI 223
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
1263-1468 7.72e-10

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 61.96  E-value: 7.72e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1263 KIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQV-----LLKGSGGGDALEFL----GYCPQ--ENALW 1331
Cdd:PRK13634   20 RRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVtigerVITAGKKNKKLKPLrkkvGIVFQfpEHQLF 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1332 PNlTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQL--KSPVKtLSEGIKRKLCF--VLSIlgNPSVVLLDEPSTG 1407
Cdd:PRK13634  100 EE-TVEKDICFGPMNFGVSEEDAKQKAREMIELVGLPEELlaRSPFE-LSGGQMRRVAIagVLAM--EPEVLVLDEPTAG 175
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   1408 MDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSK 1468
Cdd:PRK13634  176 LDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFAD 236
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
1257-1456 1.09e-09

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 60.56  E-value: 1.09e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1257 FSKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG---------------SGGGDALEFL 1321
Cdd:cd03248   21 YPTRPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGkpisqyehkylhskvSLVGQEPVLF 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1322 GYCPQENALWpNLTVRQHLEVYAAVKglrKGDAEVAITRLvdALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLL 1401
Cdd:cd03248  101 ARSLQDNIAY-GLQSCSFECVKEAAQ---KAHAHSFISEL--ASGYDTEVGEKGSQLSGGQKQRVAIARALIRNPQVLIL 174
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 6005701  1402 DEPSTGMDPEGQQQMWQAIRATfrNTERGALLTTHYMAEAEAVcDRVAIMVSGRL 1456
Cdd:cd03248  175 DEATSALDAESEQQVQQALYDW--PERRTVLVIAHRLSTVERA-DQILVLDGGRI 226
cbiO PRK13645
energy-coupling factor transporter ATPase;
1265-1481 1.33e-09

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 61.18  E-value: 1.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLL---KGSGGGDALEFLGYCPQENAL---WPNL---- 1334
Cdd:PRK13645   26 ALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVgdyAIPANLKKIKEVKRLRKEIGLvfqFPEYqlfq 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1335 -TVRQHLEVYAAVKGLRKGDAEVAITRLVDALKL-QDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEG 1412
Cdd:PRK13645  106 eTIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPKG 185
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701   1413 QQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSI------QHLKSKFGKD----YLLEMKVKN 1481
Cdd:PRK13645  186 EEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPfeifsnQELLTKIEIDppklYQLMYKLKN 264
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
1267-1475 1.42e-09

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 60.32  E-value: 1.42e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSgggDALEF--------LGYCPQENALWpNLTVRQ 1338
Cdd:cd03251   19 RDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGH---DVRDYtlaslrrqIGLVSQDVFLF-NDTVAE 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1339 HLeVYAAvkgLRKGDAEV-AITRLVDAL----KLQDQLKSPVK----TLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMD 1409
Cdd:cd03251   95 NI-AYGR---PGATREEVeEAARAANAHefimELPEGYDTVIGergvKLSGGQRQRIAIARALLKDPPILILDEATSALD 170
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701  1410 PEGQQQMWQAIRATFRNteRGALLTTHYMAEAEAVcDRVAIMVSGRLRCIGSIQHLKSKFGKDYLL 1475
Cdd:cd03251  171 TESERLVQAALERLMKN--RTTFVIAHRLSTIENA-DRIVVLEDGKIVERGTHEELLAQGGVYAKL 233
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
1267-1436 1.51e-09

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 59.97  E-value: 1.51e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITG--DTKPTAGQVLLkgsgggdaleflgycpQENALWPNLTVRQHLevya 1344
Cdd:COG2401   47 RDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGalKGTPVAGCVDV----------------PDNQFGREASLIDAI---- 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1345 avkgLRKGDAEVAITRLVDAlKLQDQ--LKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRA 1422
Cdd:COG2401  107 ----GRKGDFKDAVELLNAV-GLSDAvlWLRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRVARNLQK 181
                        170
                 ....*....|....
gi 6005701  1423 TFRNTERGALLTTH 1436
Cdd:COG2401  182 LARRAGITLVVATH 195
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
1267-1501 1.68e-09

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 63.01  E-value: 1.68e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITgDTKPTAGQVLLKG-SGGGDALE----FLGYCPQENALWPNlTVRQHLE 1341
Cdd:TIGR01271 1236 QDLSFSVEGGQRVGLLGRTGSGKSTLLSALL-RLLSTEGEIQIDGvSWNSVTLQtwrkAFGVIPQKVFIFSG-TFRKNLD 1313
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1342 VYA--AVKGLRKGDAEVAITRLVDAL--KLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMW 1417
Cdd:TIGR01271 1314 PYEqwSDEEIWKVAEEVGLKSVIEQFpdKLDFVLVDGGYVLSNGHKQLMCLARSILSKAKILLLDEPSAHLDPVTLQIIR 1393
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1418 QAIRATFRNTErgALLTTHYMaEAEAVCDRVAIMVSGRLRCIGSIQ-------HLKSKFGkdyllemkvknlaqveplHA 1490
Cdd:TIGR01271 1394 KTLKQSFSNCT--VILSEHRV-EALLECQQFLVIEGSSVKQYDSIQkllnetsLFKQAMS------------------AA 1452
                          250
                   ....*....|.
gi 6005701    1491 EILRLFPQAAR 1501
Cdd:TIGR01271 1453 DRLKLFPLHRR 1463
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
1267-1456 1.87e-09

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 60.37  E-value: 1.87e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS-------GGGDALEF-----------LGYCPQEN 1328
Cdd:PRK10619   22 KGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQtinlvrdKDGQLKVAdknqlrllrtrLTMVFQHF 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1329 ALWPNLTVRQH-LEVYAAVKGLRKGDAEVAITRLVDALKLQD--QLKSPVKtLSEGIKRKLCFVLSILGNPSVVLLDEPS 1405
Cdd:PRK10619  102 NLWSHMTVLENvMEAPIQVLGLSKQEARERAVKYLAKVGIDEraQGKYPVH-LSGGQQQRVSIARALAMEPEVLLFDEPT 180
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 6005701   1406 TGMDPEgqqQMWQAIRATFRNTERGA--LLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK10619  181 SALDPE---LVGEVLRIMQQLAEEGKtmVVVTHEMGFARHVSSHVIFLHQGKI 230
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
1265-1465 1.93e-09

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 60.41  E-value: 1.93e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIK----VITGDTKPTAGQVLL------KGSGGGD---ALEFLGYCPQENALW 1331
Cdd:PRK09984   19 ALHAVDLNIHHGEMVALLGPSGSGKSTLLRhlsgLITGDKSAGSHIELLgrtvqrEGRLARDirkSRANTGYIFQQFNLV 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1332 PNLTVRQHLEVYAA------------VKGLRKGDAEVAITRlVDALKLQDQlksPVKTLSEGIKRKLCFVLSILGNPSVV 1399
Cdd:PRK09984   99 NRLSVLENVLIGALgstpfwrtcfswFTREQKQRALQALTR-VGMVHFAHQ---RVSTLSGGQQQRVAIARALMQQAKVI 174
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701   1400 LLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHL 1465
Cdd:PRK09984  175 LADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQF 240
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
1262-1494 2.31e-09

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 60.03  E-value: 2.31e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1262 NKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG---SGGGD-----ALEFLgycPQENALWPN 1333
Cdd:PRK11231   14 TKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDkpiSMLSSrqlarRLALL---PQHHLTPEG 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1334 LTVRQHLEV----YAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGiKRKLCFVLSILG-NPSVVLLDEPSTGM 1408
Cdd:PRK11231   91 ITVRELVAYgrspWLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGG-QRQRAFLAMVLAqDTPVVLLDEPTTYL 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1409 DPEGQQQMWQAIRAtfRNTERGALLTT-HYMAEAEAVCDRVAIMVSGRLRCIGSIQHLkskfgkdylleMKVKNLAQVEP 1487
Cdd:PRK11231  170 DINHQVELMRLMRE--LNTQGKTVVTVlHDLNQASRYCDHLVVLANGHVMAQGTPEEV-----------MTPGLLRTVFD 236

                  ....*..
gi 6005701   1488 LHAEILR 1494
Cdd:PRK11231  237 VEAEIHP 243
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
1268-1492 2.45e-09

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 60.87  E-value: 2.45e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS--GGGDALE-FLGYCPQENALWPNLTVRQHLEVYA 1344
Cdd:PRK10851   20 DISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTdvSRLHARDrKVGFVFQHYALFRHMTVFDNIAFGL 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1345 AVKGLRKGDAEVAI----TRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAI 1420
Cdd:PRK10851  100 TVLPRRERPNAAAIkakvTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQVRKELRRWL 179
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701   1421 RATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFGKDYLLEMkvknLAQVEPLHAEI 1492
Cdd:PRK10851  180 RQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLEF----MGEVNRLQGTI 247
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
492-621 2.49e-09

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 61.78  E-value: 2.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    492 KPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLsVPTKGSVTIYNNKLSEMaDLE----NLSKLtGVCPQsn 567
Cdd:PRK11174  359 SPDGKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGF-LPYQGSLKINGIELREL-DPEswrkHLSWV-GQNPQ-- 433
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    568 vqfdfL---TVRENLRL---------------FAKIKGI---LPQEVDKEI---------------------------FL 599
Cdd:PRK11174  434 -----LphgTLRDNVLLgnpdasdeqlqqaleNAWVSEFlplLPQGLDTPIgdqaaglsvgqaqrlalarallqpcqlLL 508
                         170       180
                  ....*....|....*....|..
gi 6005701    600 LDEPTAGLDPFSRHQVWNLLKE 621
Cdd:PRK11174  509 LDEPTASLDAHSEQLVMQALNA 530
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
1265-1470 2.99e-09

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 61.76  E-value: 2.99e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsGGGDALEFlgycpQENALWPNLT-VRQHLEVY 1343
Cdd:PRK11160  355 VLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILL---NGQPIADY-----SEAALRQAISvVSQRVHLF 426
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1344 AAV--KGLRKGDAEVAITRLVDALK---LQDQLKSPV----------KTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGM 1408
Cdd:PRK11160  427 SATlrDNLLLAAPNASDEALIEVLQqvgLEKLLEDDKglnawlgeggRQLSGGEQRRLGIARALLHDAPLLLLDEPTEGL 506
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701   1409 DPEGQQQMWQAIRATFRNteRGALLTTHYMAEAEAVcDRVAIMVSGRLRCIGSIQHLKSKFG 1470
Cdd:PRK11160  507 DAETERQILELLAEHAQN--KTVLMITHRLTGLEQF-DRICVMDNGQIIEQGTHQELLAQQG 565
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
1265-1465 3.57e-09

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 60.12  E-value: 3.57e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGdtkptagqvLLKGSG--GGDAL----EFLGYCPQE----------- 1327
Cdd:PRK09473   31 AVNDLNFSLRAGETLGIVGESGSGKSQTAFALMG---------LLAANGriGGSATfngrEILNLPEKElnklraeqism 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1328 ------NALWPNLTV-RQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKS----PvKTLSEGIKRKLCFVLSILGNP 1396
Cdd:PRK09473  102 ifqdpmTSLNPYMRVgEQLMEVLMLHKGMSKAEAFEESVRMLDAVKMPEARKRmkmyP-HEFSGGMRQRVMIAMALLCRP 180
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701   1397 SVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHL 1465
Cdd:PRK09473  181 KLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDV 249
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
480-639 3.91e-09

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 58.25  E-value: 3.91e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPDKIE-ALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNklsemadlenlsk 558
Cdd:cd03250    1 ISVEDASFTWDSGEQETSfTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS------------- 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   559 lTGVCPQSN-VQFDflTVRENLrLFAK----------IKG--------ILPQ----EV---------------------- 593
Cdd:cd03250   68 -IAYVSQEPwIQNG--TIRENI-LFGKpfdeeryekvIKAcalepdleILPDgdltEIgekginlsggqkqrislaravy 143
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 6005701   594 -DKEIFLLDEPTAGLDPFSRHQVWN-----LLKERKTdrVILF--STQFMDEAD 639
Cdd:cd03250  144 sDADIYLLDDPLSAVDAHVGRHIFEncilgLLLNNKT--RILVthQLQLLPHAD 195
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
1245-1411 3.99e-09

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 61.10  E-value: 3.99e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1245 LRKEYAGKRKgcfskrknkiATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgSGGGDalefLGYC 1324
Cdd:TIGR03719   10 VSKVVPPKKE----------ILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARP--QPGIK----VGYL 73
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1325 PQENALWPNLTVRQHLEvyAAVKGLRKgdaevAITRL-------------VDAL-----KLQDQLKS------------- 1373
Cdd:TIGR03719   74 PQEPQLDPTKTVRENVE--EGVAEIKD-----ALDRFneisakyaepdadFDKLaaeqaELQEIIDAadawdldsqleia 146
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 6005701    1374 -----------PVKTLSEGIKRK--LCFVLsiLGNPSVVLLDEPSTGMDPE 1411
Cdd:TIGR03719  147 mdalrcppwdaDVTKLSGGERRRvaLCRLL--LSKPDMLLLDEPTNHLDAE 195
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
483-651 4.04e-09

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 61.66  E-value: 4.04e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     483 RNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSG---LSVPTKGSVTIYNNKLSemadlENLSKL 559
Cdd:TIGR00956  763 RNLTYEVKIKKEKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAErvtTGVITGGDRLVNGRPLD-----SSFQRS 837
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     560 TGVCPQSNVQFDFLTVRENLRLFAKIKgiLPQEVDKE------------------------------------------- 596
Cdd:TIGR00956  838 IGYVQQQDLHLPTSTVRESLRFSAYLR--QPKSVSKSekmeyveevikllemesyadavvgvpgeglnveqrkrltigve 915
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701     597 -------IFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILfSTQFMDEADILA--DRKVFLSQG 651
Cdd:TIGR00956  916 lvakpklLLFLDEPTSGLDSQTAWSICKLMRKlADHGQAIL-CTIHQPSAILFEefDRLLLLQKG 979
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
480-658 4.16e-09

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 57.92  E-value: 4.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKpdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLS--VPTKGSVTIYNNKLSEMADLENLS 557
Cdd:cd03217    1 LEIKDLHVSVGGK----EILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPkyEVTEGEILFKGEDITDLPPEERAR 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   558 KLTGVCPQSNVQFDFLTVRENLR-LFAKIKG----------ILPQEVDkeIFLLDEPTAGLDPFSRHQVWNLLKE-RKTD 625
Cdd:cd03217   77 LGIFLAFQYPPEIPGVKNADFLRyVNEGFSGgekkrneilqLLLLEPD--LAILDEPDSGLDIDALRLVAEVINKlREEG 154
                        170       180       190
                 ....*....|....*....|....*....|....
gi 6005701   626 RVILFSTQFMDEAD-ILADRKVFLSQGKLKCAGS 658
Cdd:cd03217  155 KSVLIITHYQRLLDyIKPDRVHVLYDGRIVKSGD 188
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
1260-1420 4.75e-09

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 58.71  E-value: 4.75e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1260 RKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGD-ALEFL----GYCPQENALWPNl 1334
Cdd:cd03249   13 RPDVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDlNLRWLrsqiGLVSQEPVLFDG- 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1335 TVRQHLEvYaavkGLRKGDAEVAITRLVDA------LKLQDQLKSPV----KTLSEGIKRKLCFVLSILGNPSVVLLDEP 1404
Cdd:cd03249   92 TIAENIR-Y----GKPDATDEEVEEAAKKAnihdfiMSLPDGYDTLVgergSQLSGGQKQRIAIARALLRNPKILLLDEA 166
                        170
                 ....*....|....*.
gi 6005701  1405 STGMDPEGQQQMWQAI 1420
Cdd:cd03249  167 TSALDAESEKLVQEAL 182
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
1262-1461 4.93e-09

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 58.91  E-value: 4.93e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1262 NKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITG-----DTK-PTAGQVLLKGSG--GGDALEF---LGYCPQENAL 1330
Cdd:PRK14246   22 DKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRlieiyDSKiKVDGKVLYFGKDifQIDAIKLrkeVGMVFQQPNP 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1331 WPNLTVRQHLEVYAAVKGLR-----KGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPS 1405
Cdd:PRK14246  102 FPHLSIYDNIAYPLKSHGIKekreiKKIVEECLRKVGLWKEVYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEPT 181
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701   1406 TGMDPEGQQQMWQAIraTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:PRK14246  182 SMIDIVNSQAIEKLI--TELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGS 235
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
478-651 5.33e-09

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 58.21  E-value: 5.33e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   478 EAIRIRNVTKEYK-----GKpdKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI-YNNKLSEMA 551
Cdd:COG4778    3 TLLEVENLSKTFTlhlqgGK--RLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVrHDGGWVDLA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   552 DLE-----NLSKLT-GVCPQsnvqfdFLTVR----------ENLR---------------LFAKIKgiLPQE-------- 592
Cdd:COG4778   81 QASpreilALRRRTiGYVSQ------FLRVIprvsaldvvaEPLLergvdreeararareLLARLN--LPERlwdlppat 152
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701   593 ----------------VDKEIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTqFMDEA--DILADRKVFLSQG 651
Cdd:COG4778  153 fsggeqqrvniargfiADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGI-FHDEEvrEAVADRVVDVTPF 228
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
1269-1461 5.62e-09

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 58.66  E-value: 5.62e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1269 VSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsgGGDALEF----------------------LGYCPQ 1326
Cdd:COG4598   27 VSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRV----GGEEIRLkpdrdgelvpadrrqlqrirtrLGMVFQ 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1327 ENALWPNLTVRQHL-EVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEG------IKRKLCFvlsilgNPSVV 1399
Cdd:COG4598  103 SFNLWSHMTVLENViEAPVHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGqqqraaIARALAM------EPEVM 176
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701  1400 LLDEPSTGMDPEGQQQMWQAIRATfrnTERGA--LLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:COG4598  177 LFDEPTSALDPELVGEVLKVMRDL---AEEGRtmLVVTHEMGFARDVSSHVVFLHQGRIEEQGP 237
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
1267-1455 6.13e-09

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 58.21  E-value: 6.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGG----DALEF---------LGYCPQenalwpN 1333
Cdd:COG4778   28 DGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDGGWvdlaQASPReilalrrrtIGYVSQ------F 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1334 LTV--RQH-LEVYAAVkGLRKG-DAEVAITR---LVDALKLQDQLKS-PVKTLSEGIKRKLCFVLSILGNPSVVLLDEPS 1405
Cdd:COG4778  102 LRVipRVSaLDVVAEP-LLERGvDREEARARareLLARLNLPERLWDlPPATFSGGEQQRVNIARGFIADPPLLLLDEPT 180
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 6005701  1406 TGMDPEGQQ---QMWQAIRAtfrnteRG-ALLT-THYMAEAEAVCDRVAIMVSGR 1455
Cdd:COG4778  181 ASLDAANRAvvvELIEEAKA------RGtAIIGiFHDEEVREAVADRVVDVTPFS 229
hmuV PRK13547
heme ABC transporter ATP-binding protein;
1260-1456 6.72e-09

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 58.68  E-value: 6.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1260 RKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGD-TKPTA-------GQVLLKGS--GGGDALEFL---GYCPQ 1326
Cdd:PRK13547   11 RRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDlTGGGAprgarvtGDVTLNGEplAAIDAPRLArlrAVLPQ 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1327 ENALWPNLTVRQ--------HLEVYAAVKGLRKGDAEVAITRL-VDALKLQDqlkspVKTLSEGIKRKLCF--VLSIL-- 1393
Cdd:PRK13547   91 AAQPAFAFSAREivllgrypHARRAGALTHRDGEIAWQALALAgATALVGRD-----VTTLSGGELARVQFarVLAQLwp 165
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701   1394 -----GNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK13547  166 phdaaQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAI 233
cbiO PRK13645
energy-coupling factor transporter ATPase;
480-658 6.88e-09

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 58.87  E-value: 6.88e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYKGK-PDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNK----LSEMADLE 554
Cdd:PRK13645    7 IILDNVSYTYAKKtPFEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAipanLKKIKEVK 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    555 NLSKLTGVCPQ------------SNVQFDFLTVRENLR-LFAKIKGIL-----PQE------------------------ 592
Cdd:PRK13645   87 RLRKEIGLVFQfpeyqlfqetieKDIAFGPVNLGENKQeAYKKVPELLklvqlPEDyvkrspfelsggqkrrvalagiia 166
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701    593 VDKEIFLLDEPTAGLDPFSRHQVWNL---LKERKTDRVILFsTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:PRK13645  167 MDGNTLVLDEPTGGLDPKGEEDFINLferLNKEYKKRIIMV-THNMDQVLRIADEVIVMHEGKVISIGS 234
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
479-542 7.02e-09

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 59.47  E-value: 7.02e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701    479 AIRIRNVTKEYKGKpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI 542
Cdd:PRK11650    3 GLKLQAVRKSYDGK---TQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWI 63
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
1257-1456 7.26e-09

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 58.25  E-value: 7.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1257 FSKRKnkiATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVIT--GDTKP---TAGQVLLKG----SGGGDALEF---LGYC 1324
Cdd:PRK14239   15 YNKKK---ALNSVSLDFYPNEITALIGPSGSGKSTLLRSINrmNDLNPevtITGSIVYNGhniySPRTDTVDLrkeIGMV 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1325 PQENALWPnltvrqhLEVYA-AVKGLR-KG--DAEVAITRLVDALK-------LQDQLKSPVKTLSEGIKRKLCFVLSIL 1393
Cdd:PRK14239   92 FQQPNPFP-------MSIYEnVVYGLRlKGikDKQVLDEAVEKSLKgasiwdeVKDRLHDSALGLSGGQQQRVCIARVLA 164
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701   1394 GNPSVVLLDEPSTGMDPEGQQQmwqaIRATFRNTERG--ALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK14239  165 TSPKIILLDEPTSALDPISAGK----IEETLLGLKDDytMLLVTRSMQQASRISDRTGFFLDGDL 225
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
469-580 7.68e-09

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 60.22  E-value: 7.68e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   469 QAPPEFQGKEAIRIRNVTKEYKgkPDKiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIynnkls 548
Cdd:COG5265  347 DAPPLVVGGGEVRFENVSFGYD--PER-PILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILI------ 417
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 6005701   549 emaDLENLSKLT--------GVCPQSNVQF-DflTVRENLR 580
Cdd:COG5265  418 ---DGQDIRDVTqaslraaiGIVPQDTVLFnD--TIAYNIA 453
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
480-638 7.84e-09

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 57.42  E-value: 7.84e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMaDLENLSKL 559
Cdd:cd03369    7 IEVENLSVRYA--PDLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTI-PLEDLRSS 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFlTVRENLRLFAKIKgilpqevDKEIFLLDEPTAGLDPFSRHQVWNLLKER---KTDRVILfstqfMD 636
Cdd:cd03369   84 LTIIPQDPTLFSG-TIRSNLDPFDEYS-------DEEIYGALRVSEGGLNLSQGQRQLLCLARallKRPRVLV-----LD 150

                 ..
gi 6005701   637 EA 638
Cdd:cd03369  151 EA 152
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
482-559 8.14e-09

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 60.12  E-value: 8.14e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701    482 IRNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMaDLENLSKL 559
Cdd:PRK10535    7 LKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATL-DADALAQL 83
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
1268-1456 9.13e-09

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 57.80  E-value: 9.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSG--GGDALEFL-----GYCPQENALWPNLTVrqhL 1340
Cdd:PRK09493   19 NIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKvnDPKVDERLirqeaGMVFQQFYLFPHLTA---L 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1341 EVYA----AVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQM 1416
Cdd:PRK09493   96 ENVMfgplRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTSALDPELRHEV 175
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 6005701   1417 WQAIRATfrnTERG--ALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK09493  176 LKVMQDL---AEEGmtMVIVTHEIGFAEKVASRLIFIDKGRI 214
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
1268-1455 9.68e-09

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 59.72  E-value: 9.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1268 NVSFCVRKGEVLGLLGHNGAGKS-TSIKVI-----------TGDTKpTAGQVLLKGS--------GGGDALEFlgycpQE 1327
Cdd:PRK15134   27 DVSLQIEAGETLALVGESGSGKSvTALSILrllpsppvvypSGDIR-FHGESLLHASeqtlrgvrGNKIAMIF-----QE 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1328 N--ALWPNLTVRQHL-EVYAAVKGLRKGDAEVAITRLVDALKLQD---QLKSPVKTLSEGIKRKLCFVLSILGNPSVVLL 1401
Cdd:PRK15134  101 PmvSLNPLHTLEKQLyEVLSLHRGMRREAARGEILNCLDRVGIRQaakRLTDYPHQLSGGERQRVMIAMALLTRPELLIA 180
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 6005701   1402 DEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGR 1455
Cdd:PRK15134  181 DEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGR 234
cbiO PRK13640
energy-coupling factor transporter ATPase;
1263-1482 9.95e-09

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 58.27  E-value: 9.95e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1263 KIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGdtkptagqVLLKGSGGGDALEFLGYCPQENALWpnlTVRQHLE- 1341
Cdd:PRK13640   20 KPALNDISFSIPRGSWTALIGHNGSGKSTISKLING--------LLLPDDNPNSKITVDGITLTAKTVW---DIREKVGi 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1342 ---------VYAAV----------KGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCfVLSILG-NPSVVLL 1401
Cdd:PRK13640   89 vfqnpdnqfVGATVgddvafglenRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVA-IAGILAvEPKIIIL 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1402 DEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEA-----VCDRVAIMVSGRLRCIGSIQHLKSKFGKDYLLE 1476
Cdd:PRK13640  168 DESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEANMadqvlVLDDGKLLAQGSPVEIFSKVEMLKEIGLDIPFV 247

                  ....*.
gi 6005701   1477 MKVKNL 1482
Cdd:PRK13640  248 YKLKNK 253
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
1276-1456 1.20e-08

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 57.77  E-value: 1.20e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1276 GEVLGLLGHNGAGKSTSIKVITGDTKPTAGQvLLKGSGG-GDALEFLGYCPQENALWPNLTVRQHLEVyaavkGLrKGDA 1354
Cdd:PRK11247   38 GQFVAVVGRSGCGKSTLLRLLAGLETPSAGE-LLAGTAPlAEAREDTRLMFQDARLLPWKKVIDNVGL-----GL-KGQW 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1355 EVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLT 1434
Cdd:PRK11247  111 RDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEMQDLIESLWQQHGFTVLLV 190
                         170       180
                  ....*....|....*....|..
gi 6005701   1435 THYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK11247  191 THDVSEAVAMADRVLLIEEGKI 212
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
1276-1420 1.20e-08

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 59.80  E-value: 1.20e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1276 GEVLGLLGHNGAGKSTSIKVITGDTKPTAGQV-LLKGSGGG----DALEFLGycPQENALwpnltvrQHLEVYAavkglr 1350
Cdd:PRK10636  338 GSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIgLAKGIKLGyfaqHQLEFLR--ADESPL-------QHLARLA------ 402
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   1351 KGDAEVAITRLVDALKLQ-DQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAI 1420
Cdd:PRK10636  403 PQELEQKLRDYLGGFGFQgDKVTEETRRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEAL 473
PLN03140 PLN03140
ABC transporter G family member; Provisional
1267-1436 1.22e-08

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 60.24  E-value: 1.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGdtKPTAGQVL--LKGSGGGDALEFL----GYCPQENALWPNLTVRQHL 1340
Cdd:PLN03140  897 REVTGAFRPGVLTALMGVSGAGKTTLMDVLAG--RKTGGYIEgdIRISGFPKKQETFarisGYCEQNDIHSPQVTVRESL 974
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1341 eVYAAVKGLRKGDAEVAITRLVDA---LKLQDQLKSP------VKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPE 1411
Cdd:PLN03140  975 -IYSAFLRLPKEVSKEEKMMFVDEvmeLVELDNLKDAivglpgVTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDAR 1053
                         170       180
                  ....*....|....*....|....*
gi 6005701   1412 GQQQMWQAIRATFrNTERGALLTTH 1436
Cdd:PLN03140 1054 AAAIVMRTVRNTV-DTGRTVVCTIH 1077
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
1280-1411 1.25e-08

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 59.36  E-value: 1.25e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1280 GLLGHNGAGKSTSIKVITGDTKPTAGQ-VLLKGSGggdalefLGYCPQENALWPNLTVRQHLEvyAAVkglrkGDAEVAI 1358
Cdd:PRK11819   37 GVLGLNGAGKSTLLRIMAGVDKEFEGEaRPAPGIK-------VGYLPQEPQLDPEKTVRENVE--EGV-----AEVKAAL 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1359 TRL-------------VDAL-----KLQDQLKS------------------------PVKTLSEGIKRK--LCFVLsiLG 1394
Cdd:PRK11819  103 DRFneiyaayaepdadFDALaaeqgELQEIIDAadawdldsqleiamdalrcppwdaKVTKLSGGERRRvaLCRLL--LE 180
                         170
                  ....*....|....*..
gi 6005701   1395 NPSVVLLDEPSTGMDPE 1411
Cdd:PRK11819  181 KPDMLLLDEPTNHLDAE 197
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
1269-1457 1.34e-08

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 57.10  E-value: 1.34e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1269 VSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSG-------GGDAL--EFLGYCPQENALWPNLTVRQH 1339
Cdd:PRK10584   29 VELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPlhqmdeeARAKLraKHVGFVFQSFMLIPTLNALEN 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1340 LEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQA 1419
Cdd:PRK10584  109 VELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADL 188
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 6005701   1420 IRATFRNTERGALLTTHYMAEAeAVCDRVAIMVSGRLR 1457
Cdd:PRK10584  189 LFSLNREHGTTLILVTHDLQLA-ARCDRRLRLVNGQLQ 225
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
483-652 1.42e-08

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 59.29  E-value: 1.42e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     483 RNVTKEYKGKPDKIeALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVP-TKGSVTIYNNklSEMADLENLSKLTG 561
Cdd:TIGR00955   26 RLRGCFCRERPRKH-LLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKgVKGSGSVLLN--GMPIDAKEMRAISA 102
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     562 VCPQSNVQFDFLTVRENL----------RLFAKIKGILPQEV-------------------------------------- 593
Cdd:TIGR00955  103 YVQQDDLFIPTLTVREHLmfqahlrmprRVTKKEKRERVDEVlqalglrkcantrigvpgrvkglsggerkrlafasell 182
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701     594 -DKEIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADI--LADRKVFLSQGK 652
Cdd:TIGR00955  183 tDPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSELfeLFDKIILMAEGR 244
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
498-658 1.43e-08

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 58.89  E-value: 1.43e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    498 ALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLS---KLTGVCPQSNVQFDFLT 574
Cdd:PRK10070   43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREvrrKKIAMVFQSFALMPHMT 122
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    575 VRENLRLFAKIKGILPQE----------------------------------------VDKEIFLLDEPTAGLDPFSRHQ 614
Cdd:PRK10070  123 VLDNTAFGMELAGINAEErrekaldalrqvglenyahsypdelsggmrqrvglaralaINPDILLMDEAFSALDPLIRTE 202
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 6005701    615 VWN-LLK-ERKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:PRK10070  203 MQDeLVKlQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGT 248
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
1267-1456 1.44e-08

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 59.29  E-value: 1.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS-----GGGDALEF-LGYCPQEnalwpnltvRQ-- 1338
Cdd:PRK15439  280 RNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKeinalSTAQRLARgLVYLPED---------RQss 350
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1339 --HLE------VYAAVKGLR----KGDAEVAI-TRLVDALKLQ-DQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEP 1404
Cdd:PRK15439  351 glYLDaplawnVCALTHNRRgfwiKPARENAVlERYRRALNIKfNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEP 430
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 6005701   1405 STGMDPEGQQQMWQAIRA-TFRNTerGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK15439  431 TRGVDVSARNDIYQLIRSiAAQNV--AVLFISSDLEEIEQMADRVLVMHQGEI 481
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
480-658 1.49e-08

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 57.89  E-value: 1.49e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYKGKpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEmADLENLSKL 559
Cdd:PRK13652    4 IETRDLCYSYSGS---KEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITK-ENIREVRKF 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    560 TGVCPQS-------------------NVQFDFLTVR----ENLRLFA--------------------KIKGILPQEvdKE 596
Cdd:PRK13652   80 VGLVFQNpddqifsptveqdiafgpiNLGLDEETVAhrvsSALHMLGleelrdrvphhlsggekkrvAIAGVIAME--PQ 157
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701    597 IFLLDEPTAGLDPFSRHQVW---NLLKERKTDRVIlFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:PRK13652  158 VLVLDEPTAGLDPQGVKELIdflNDLPETYGMTVI-FSTHQLDLVPEMADYIYVMDKGRIVAYGT 221
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
1268-1454 1.61e-08

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 57.45  E-value: 1.61e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLlkgsgggdaleFLGYCPQENalwpNLT-VRQHLEV---- 1342
Cdd:PRK13648   27 DVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIF-----------YNNQAITDD----NFEkLRKHIGIvfqn 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1343 -----------YAAVKGLRK-----GDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPST 1406
Cdd:PRK13648   92 pdnqfvgsivkYDVAFGLENhavpyDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATS 171
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 6005701   1407 GMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAeAVCDRVAIMVSG 1454
Cdd:PRK13648  172 MLDPDARQNLLDLVRKVKSEHNITIISITHDLSEA-MEADHVIVMNKG 218
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
436-581 1.79e-08

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 59.20  E-value: 1.79e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    436 FLKSSFWSQTQKTDHVALEDEMdadPSFHDSfEQAPPEFQGKEAIRIRNVTKEYKGKPdkiEALKDLVFDIYEGQITAIL 515
Cdd:PRK13657  295 FINQVFMAAPKLEEFFEVEDAV---PDVRDP-PGAIDLGRVKGAVEFDDVSFSYDNSR---QGVEDVSFEAKPGQTVAIV 367
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701    516 GHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMAdLENLSKLTGVCPQSNVQFDfLTVRENLRL 581
Cdd:PRK13657  368 GPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVT-RASLRRNIAVVFQDAGLFN-RSIEDNIRV 431
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
1265-1479 1.80e-08

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 58.86  E-value: 1.80e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG-----SGGGDALEF-LGYCPQENALWPNLTVRQ 1338
Cdd:PRK10762   19 ALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGkevtfNGPKSSQEAgIGIIHQELNLIPQLTIAE 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1339 HL----EVYAAVKGL--RKGDAEVaiTRLVDALKLQDQLKSPVKTLSEG------IKRKLCFvlsilgNPSVVLLDEPST 1406
Cdd:PRK10762   99 NIflgrEFVNRFGRIdwKKMYAEA--DKLLARLNLRFSSDKLVGELSIGeqqmveIAKVLSF------ESKVIIMDEPTD 170
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6005701   1407 GMDPEGQQQMWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLrcIGsiQHLKSKFGKDYLLEMKV 1479
Cdd:PRK10762  171 ALTDTETESLFRVIR-ELKSQGRGIVYISHRLKEIFEICDDVTVFRDGQF--IA--EREVADLTEDSLIEMMV 238
cbiO PRK13642
energy-coupling factor transporter ATPase;
1269-1456 1.87e-08

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 57.41  E-value: 1.87e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1269 VSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS-----GGGDALEFLGYCPQE-NALWPNLTVRQHLEV 1342
Cdd:PRK13642   26 VSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGElltaeNVWNLRRKIGMVFQNpDNQFVGATVEDDVAF 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1343 YAAVKGLRKgdaEVAITRLVDAL----KLQDQLKSPVKtLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQ 1418
Cdd:PRK13642  106 GMENQGIPR---EEMIKRVDEALlavnMLDFKTREPAR-LSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMR 181
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 6005701   1419 AIRATFRNTERGALLTTHYMAEAeAVCDRVAIMVSGRL 1456
Cdd:PRK13642  182 VIHEIKEKYQLTVLSITHDLDEA-ASSDRILVMKAGEI 218
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
482-552 1.94e-08

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 56.99  E-value: 1.94e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701    482 IRNVTKEYKGKpdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMAD 552
Cdd:PRK11247   15 LNAVSKRYGER----TVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAEARE 81
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
1267-1460 2.06e-08

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 57.16  E-value: 2.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITG--DTKPTA---GQVLLKG----SGGGDALEF---LGYCPQENALWPNL 1334
Cdd:PRK14267   21 KGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRllELNEEArveGEVRLFGrniySPDVDPIEVrreVGMVFQYPNPFPHL 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1335 TVRQHLEVYAAVKGLRKGDAEVAiTRLVDALK-------LQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTG 1407
Cdd:PRK14267  101 TIYDNVAIGVKLNGLVKSKKELD-ERVEWALKkaalwdeVKDRLNDYPSNLSGGQRQRLVIARALAMKPKILLMDEPTAN 179
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 6005701   1408 MDPEGQQQMWQAIRATfrNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIG 1460
Cdd:PRK14267  180 IDPVGTAKIEELLFEL--KKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVG 230
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
483-652 2.18e-08

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 56.12  E-value: 2.18e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   483 RNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPT---KGSVTiYNNKLSemadLENLSKL 559
Cdd:cd03233    7 RNISFTTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIH-YNGIPY----KEFAEKY 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TG---VCPQSNVQFDFLTVRENLRLFAK------IKGI---------LPQEVDKE--IFLLDEPTAGLDPFSRHQVWNLL 619
Cdd:cd03233   82 PGeiiYVSEEDVHFPTLTVRETLDFALRckgnefVRGIsggerkrvsIAEALVSRasVLCWDNSTRGLDSSTALEILKCI 161
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 6005701   620 KE--RKTDRVILFS-TQFMDEADILADRKVFLSQGK 652
Cdd:cd03233  162 RTmaDVLKTTTFVSlYQASDEIYDLFDKVLVLYEGR 197
cbiO PRK13646
energy-coupling factor transporter ATPase;
1265-1456 2.23e-08

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 57.48  E-value: 2.23e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsgggDALEF---------------LGYCPQ--E 1327
Cdd:PRK13646   22 AIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTV------DDITIthktkdkyirpvrkrIGMVFQfpE 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1328 NALWPNLTVRqhlEVYAAVKGLRKGDAEVAitrlVDALKLQDQL--------KSPVKtLSEGIKRKLCFVlSILG-NPSV 1398
Cdd:PRK13646   96 SQLFEDTVER---EIIFGPKNFKMNLDEVK----NYAHRLLMDLgfsrdvmsQSPFQ-MSGGQMRKIAIV-SILAmNPDI 166
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701   1399 VLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK13646  167 IVLDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSI 224
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
1266-1460 2.25e-08

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 58.12  E-value: 2.25e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1266 TRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGD---ALEFLGYCPQENALWPNLTVRQHLEV 1342
Cdd:PRK11000   19 SKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDvppAERGVGMVFQSYALYPHLSVAENMSF 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1343 YAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRA 1422
Cdd:PRK11000   99 GLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMRIEISR 178
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 6005701   1423 TFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIG 1460
Cdd:PRK11000  179 LHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVG 216
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
1258-1456 2.64e-08

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 57.55  E-value: 2.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1258 SKRKNKI-ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALEFLGYCPQENA------- 1329
Cdd:PRK13631   33 EKQENELvALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDIYIGDKKNNHELITNPYSkkiknfk 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1330 ----------LWPNL-----TVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQL--KSPVKtLSEGIKRKLCF--VL 1390
Cdd:PRK13631  113 elrrrvsmvfQFPEYqlfkdTIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLDDSYleRSPFG-LSGGQKRRVAIagIL 191
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701   1391 SIlgNPSVVLLDEPSTGMDPEGQQQMWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK13631  192 AI--QPEILIFDEPTAGLDPKGEHEMMQLIL-DAKANNKTVFVITHTMEHVLEVADEVIVMDKGKI 254
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
477-653 2.87e-08

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 56.77  E-value: 2.87e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    477 KEAIRIRNVTKEYKGKpdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGL-----SVPTKGSVTIYN-NKLSEM 550
Cdd:PRK14267    2 KFAIETVNLRVYYGSN----HVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLlelneEARVEGEVRLFGrNIYSPD 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    551 ADLENLSKLTGVCPQSNVQFDFLTVRENLRLFAKIKGILP--QEVDK--------------------------------- 595
Cdd:PRK14267   78 VDPIEVRREVGMVFQYPNPFPHLTIYDNVAIGVKLNGLVKskKELDErvewalkkaalwdevkdrlndypsnlsggqrqr 157
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701    596 -----------EIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:PRK14267  158 lviaralamkpKILLMDEPTANIDPVGTAKIEELLFELKKEYTIVLVTHSPAQAARVSDYVAFLYLGKL 226
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
479-648 3.05e-08

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 56.58  E-value: 3.05e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYkgkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLS-----VPTKGSVTIYNNKLSE-MAD 552
Cdd:PRK14258    7 AIKVNNLSFYY----DTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNeleseVRVEGRVEFFNQNIYErRVN 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    553 LENLSK-LTGVCPQSNVqFDfLTVRENLRLFAKIKGILPQ-EVD------------------------------------ 594
Cdd:PRK14258   83 LNRLRRqVSMVHPKPNL-FP-MSVYDNVAYGVKIVGWRPKlEIDdivesalkdadlwdeikhkihksaldlsggqqqrlc 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701    595 --------KEIFLLDEPTAGLDPFSRHQVWNLLKER--KTDRVILFSTQFMDEADILADRKVFL 648
Cdd:PRK14258  161 iaralavkPKVLLMDEPCFGLDPIASMKVESLIQSLrlRSELTMVIVSHNLHQVSRLSDFTAFF 224
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
498-649 3.07e-08

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 56.71  E-value: 3.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    498 ALKDLVFDIYEGQITAILGHSGAGKSTLL---NILSGL--SVPTKGSVTIYNNKL--SEMADLENLSKLTGVC------P 564
Cdd:PRK14243   25 AVKNVWLDIPKNQITAFIGPSGCGKSTILrcfNRLNDLipGFRVEGKVTFHGKNLyaPDVDPVEVRRRIGMVFqkpnpfP 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    565 QS---NVQF-----------DFLtVRENLR---LFAKIKGILPQE-------------------VDKEIFLLDEPTAGLD 608
Cdd:PRK14243  105 KSiydNIAYgaringykgdmDEL-VERSLRqaaLWDEVKDKLKQSglslsggqqqrlciaraiaVQPEVILMDEPCSALD 183
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 6005701    609 PFSRHQVWNLLKERKTDRVILFSTQFMDEADILADRKVFLS 649
Cdd:PRK14243  184 PISTLRIEELMHELKEQYTIIIVTHNMQQAARVSDMTAFFN 224
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
480-554 3.68e-08

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 57.98  E-value: 3.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYKGKPDKIEALKDLV----------------FDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI- 542
Cdd:PRK13545    5 VKFEHVTKKYKMYNKPFDKLKDLFfrskdgeyhyalnnisFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIk 84
                          90       100
                  ....*....|....*....|...
gi 6005701    543 -----------YNNKLSEMADLE 554
Cdd:PRK13545   85 gsaaliaissgLNGQLTGIENIE 107
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
484-658 3.74e-08

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 56.06  E-value: 3.74e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    484 NVTKEYKGKpdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLSKLTGVC 563
Cdd:PRK10895    8 NLAKAYKGR----RVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARARRGIGYL 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    564 PQSNVQFDFLTVRENLRLFAKIKGILPQEVDKE-----------------------------------------IFLLDE 602
Cdd:PRK10895   84 PQEASIFRRLSVYDNLMAVLQIRDDLSAEQREDranelmeefhiehlrdsmgqslsggerrrveiaralaanpkFILLDE 163
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701    603 PTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGS 658
Cdd:PRK10895  164 PFAGVDPISVIDIKRIIEHlRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGT 220
cbiO PRK13650
energy-coupling factor transporter ATPase;
480-658 4.19e-08

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 56.28  E-value: 4.19e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYKGKPDKIeALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLSKL 559
Cdd:PRK13650    5 IEVKNLTFKYKEDQEKY-TLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVWDIRHKI 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    560 TGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEV-----------------DKE-----------------------IFL 599
Cdd:PRK13650   84 GMVFQNPDNQFVGATVEDDVAFGLENKGIPHEEMkervnealelvgmqdfkEREparlsggqkqrvaiagavamrpkIII 163
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701    600 LDEPTAGLDPFSRHQVWNLLKERKTDR--VILFSTQFMDEAdILADRKVFLSQGKLKCAGS 658
Cdd:PRK13650  164 LDEATSMLDPEGRLELIKTIKGIRDDYqmTVISITHDLDEV-ALSDRVLVMKNGQVESTST 223
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
1273-1421 5.12e-08

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 55.84  E-value: 5.12e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1273 VRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALEFLGYCPQ-------ENALWPNLTVRQHLEVYAA 1345
Cdd:cd03236   23 PREGQVLGLVGPNGIGKSTALKILAGKLKPNLGKFDDPPDWDEILDEFRGSELQnyftkllEGDVKVIVKPQYVDLIPKA 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1346 VKG-----LRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAI 1420
Cdd:cd03236  103 VKGkvgelLKKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRLNAARLI 182

                 .
gi 6005701  1421 R 1421
Cdd:cd03236  183 R 183
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
471-542 5.27e-08

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 57.64  E-value: 5.27e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701     471 PPEFQGKEAIRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI 542
Cdd:TIGR03719  314 PGPRLGDKVIEAENLTKAFGDKL----LIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI 381
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
501-592 5.65e-08

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 54.81  E-value: 5.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    501 DLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEM-----ADLENLSKLTGVCPQsnvqfdfLTV 575
Cdd:PRK13538   19 GLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQrdeyhQDLLYLGHQPGIKTE-------LTA 91
                          90
                  ....*....|....*..
gi 6005701    576 RENLRLFAKIKGILPQE 592
Cdd:PRK13538   92 LENLRFYQRLHGPGDDE 108
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
1253-1460 5.82e-08

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 57.56  E-value: 5.82e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1253 RKGCFSKRKNKI-ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG------SGGG-----DALEF 1320
Cdd:PRK10261  326 RSGLLNRVTREVhAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGqridtlSPGKlqalrRDIQF 405
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1321 LGYCPQEnALWPNLTVRQHLEVYAAVKGLRKGDAEVA-ITRLVD--ALKLQDQLKSPvKTLSEGIKRKLCFVLSILGNPS 1397
Cdd:PRK10261  406 IFQDPYA-SLDPRQTVGDSIMEPLRVHGLLPGKAAAArVAWLLErvGLLPEHAWRYP-HEFSGGQRQRICIARALALNPK 483
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6005701   1398 VVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIG 1460
Cdd:PRK10261  484 VIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
480-548 6.20e-08

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 55.95  E-value: 6.20e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701    480 IRIRNVTKEYKGKP-----DKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLS 548
Cdd:PRK15112    5 LEVRNLSKTFRYRTgwfrrQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLH 78
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
1273-1450 7.58e-08

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 54.12  E-value: 7.58e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1273 VRKGEVLGLLGHNGAGKSTSIKVITGDTKPTagqvllkgsgggdaleflgycpQENALWPNLTVrqhleVYaavkglrkg 1352
Cdd:cd03222   22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPN----------------------GDNDEWDGITP-----VY--------- 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1353 daevaitrlvdalklqdqlKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGAL 1432
Cdd:cd03222   66 -------------------KPQYIDLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKKTAL 126
                        170
                 ....*....|....*...
gi 6005701  1433 LTTHYMAEAEAVCDRVAI 1450
Cdd:cd03222  127 VVEHDLAVLDYLSDRIHV 144
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
1267-1455 7.63e-08

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 54.40  E-value: 7.63e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSgggdalefLGYCPQENalW-PNLTVRQHL----- 1340
Cdd:cd03250   22 KDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS--------IAYVSQEP--WiQNGTIRENIlfgkp 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1341 ---EVYAAVkglrkgdaevaitrlVDALKLQDQLKSPVK-----------TLSEGIKRKLCFVLSILGNPSVVLLDEPST 1406
Cdd:cd03250   92 fdeERYEKV---------------IKACALEPDLEILPDgdlteigekgiNLSGGQKQRISLARAVYSDADIYLLDDPLS 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 6005701  1407 GMDPE-GQQQMWQAIRATFRNtERGALLTTHYMAEAEAvCDRVAIMVSGR 1455
Cdd:cd03250  157 AVDAHvGRHIFENCILGLLLN-NKTRILVTHQLQLLPH-ADQIVVLDNGR 204
ycf16 CHL00131
sulfate ABC transporter protein; Validated
1267-1474 7.80e-08

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 55.42  E-value: 7.80e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITG--DTKPTAGQVLLKGSgggDALEFLgycPQEnalwpnltvRQHLEVYA 1344
Cdd:CHL00131   24 KGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGhpAYKILEGDILFKGE---SILDLE---PEE---------RAHLGIFL 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1345 A------VKGLRKGDaevaITRLVDALKLQDQLKSPVKTLS--EGIKRKLCFV------LS------------------- 1391
Cdd:CHL00131   89 AfqypieIPGVSNAD----FLRLAYNSKRKFQGLPELDPLEflEIINEKLKLVgmdpsfLSrnvnegfsggekkrneilq 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1392 -ILGNPSVVLLDEPSTGMDPEGQQQMWQAIRaTFRNTERGALLTTHYMAEAEAVC-DRVAIMVSGRLRCIGSIQ--HLKS 1467
Cdd:CHL00131  165 mALLDSELAILDETDSGLDIDALKIIAEGIN-KLMTSENSIILITHYQRLLDYIKpDYVHVMQNGKIIKTGDAElaKELE 243

                  ....*..
gi 6005701   1468 KFGKDYL 1474
Cdd:CHL00131  244 KKGYDWL 250
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
1268-1457 8.00e-08

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 56.76  E-value: 8.00e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITG------------DTKPTAGQVLLKGSGGGDALeflgyCPQE---NALWP 1332
Cdd:TIGR02633  278 DVSFSLRRGEILGVAGLVGAGRTELVQALFGaypgkfegnvfiNGKPVDIRNPAQAIRAGIAM-----VPEDrkrHGIVP 352
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1333 NLTVRQH--LEVYAAVKGLRKGDAEV---AITRLVDALKLQDQLKS-PVKTLSEGIKRKLCFVLSILGNPSVVLLDEPST 1406
Cdd:TIGR02633  353 ILGVGKNitLSVLKSFCFKMRIDAAAelqIIGSAIQRLKVKTASPFlPIGRLSGGNQQKAVLAKMLLTNPRVLILDEPTR 432
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 6005701    1407 GMDPEGQQQMWQAIRATFRnteRGA--LLTTHYMAEAEAVCDRVAIMVSGRLR 1457
Cdd:TIGR02633  433 GVDVGAKYEIYKLINQLAQ---EGVaiIVVSSELAEVLGLSDRVLVIGEGKLK 482
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
496-653 8.03e-08

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 55.30  E-value: 8.03e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    496 IEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGL-----SVPTKGSVTIYNNKLSEMaDLENLSKLTGVCPQSNVQF 570
Cdd:PRK14247   16 VEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDGQDIFKM-DVIELRRRVQMVFQIPNPI 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    571 DFLTVRENLRLFAKI-------------------KGILPQEV---------------------------DKEIFLLDEPT 604
Cdd:PRK14247   95 PNLSIFENVALGLKLnrlvkskkelqervrwaleKAQLWDEVkdrldapagklsggqqqrlciaralafQPEVLLADEPT 174
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 6005701    605 AGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADILADRKVFLSQGKL 653
Cdd:PRK14247  175 ANLDPENTAKIESLFLELKKDMTIVLVTHFPQQAARISDYVAFLYKGQI 223
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
1267-1444 8.65e-08

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 57.04  E-value: 8.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSG----GGDAL-----EFLGYCPQENALWPNLTVR 1337
Cdd:PRK10535   25 KGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDvatlDADALaqlrrEHFGFIFQRYHLLSHLTAA 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1338 QHLEVYAAVKGL----RKGDAEVAITRlvdaLKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPE-G 1412
Cdd:PRK10535  105 QNVEVPAVYAGLerkqRLLRAQELLQR----LGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHsG 180
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 6005701   1413 QQQMwqAIRATFRNTERGALLTTH---YMAEAEAV 1444
Cdd:PRK10535  181 EEVM--AILHQLRDRGHTVIIVTHdpqVAAQAERV 213
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
1267-1471 8.86e-08

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 57.43  E-value: 8.86e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDT----KPTAGQVLLKGSGGGDALEF----LGYCPQENALWPNLTVRQ 1338
Cdd:TIGR00956   78 KPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNTdgfhIGVEGVITYDGITPEEIKKHyrgdVVYNAETDVHFPHLTVGE 157
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1339 HLEVYAAVKGlrKGDAEVAITRLVDALKLQDQLKSP---------------VKTLSEGIKRKLCFVLSILGNPSVVLLDE 1403
Cdd:TIGR00956  158 TLDFAARCKT--PQNRPDGVSREEYAKHIADVYMATyglshtrntkvgndfVRGVSGGERKRVSIAEASLGGAKIQCWDN 235
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1404 PSTGMDPEGQQQMWQAIRATFRNTERGALLTThYMAEAEA--VCDRVAIMVSGRLRCIGSIQHLKSKFGK 1471
Cdd:TIGR00956  236 ATRGLDSATALEFIRALKTSANILDTTPLVAI-YQCSQDAyeLFDKVIVLYEGYQIYFGPADKAKQYFEK 304
PLN03211 PLN03211
ABC transporter G-25; Provisional
1276-1409 9.61e-08

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 56.81  E-value: 9.61e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1276 GEVLGLLGHNGAGKSTSIKVITGDTKPT--AGQVLLKGSG-GGDALEFLGYCPQENALWPNLTVRQHLeVYAAVKGLRKG 1352
Cdd:PLN03211   94 GEILAVLGPSGSGKSTLLNALAGRIQGNnfTGTILANNRKpTKQILKRTGFVTQDDILYPHLTVRETL-VFCSLLRLPKS 172
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701   1353 DAEVAITRLVDAL-------KLQDQL--KSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMD 1409
Cdd:PLN03211  173 LTKQEKILVAESViselgltKCENTIigNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLD 238
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
482-542 1.07e-07

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 56.61  E-value: 1.07e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   482 IRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI 542
Cdd:COG0488    1 LENLSKSFGGRP----LLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSI 57
PLN03130 PLN03130
ABC transporter C family member; Provisional
471-582 1.67e-07

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 56.28  E-value: 1.67e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    471 PPEFQGKEAIRIRNVTKEYKgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEM 550
Cdd:PLN03130 1229 PPGWPSSGSIKFEDVVLRYR--PELPPVLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKF 1306
                          90       100       110
                  ....*....|....*....|....*....|..
gi 6005701    551 AdLENLSKLTGVCPQSNVQFDFlTVRENLRLF 582
Cdd:PLN03130 1307 G-LMDLRKVLGIIPQAPVLFSG-TVRFNLDPF 1336
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
1257-1457 2.08e-07

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 54.27  E-value: 2.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1257 FSKRKNKIaTRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITgDTKPTAGQVLLKGSgggdaLEFLGYCPQENALWPNLTV 1336
Cdd:PRK14258   15 FYYDTQKI-LEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLN-RMNELESEVRVEGR-----VEFFNQNIYERRVNLNRLR 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1337 RQ-----------HLEVYAAVK-GLR------KGDAEVAITRLVDALKLQDQLKSPVKT----LSEGIKRKLCFVLSILG 1394
Cdd:PRK14258   88 RQvsmvhpkpnlfPMSVYDNVAyGVKivgwrpKLEIDDIVESALKDADLWDEIKHKIHKsaldLSGGQQQRLCIARALAV 167
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6005701   1395 NPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR 1457
Cdd:PRK14258  168 KPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGNENR 230
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
509-651 2.12e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 51.99  E-value: 2.12e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701      509 GQITAILGHSGAGKSTLLNILSGLSVPTKGSVtIYNNKLSEMADLENLSKLTGVCPQSNVQFDFLTVRenlRLFAKIKgi 588
Cdd:smart00382    2 GEVILIVGPPGSGKTTLARALARELGPPGGGV-IYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLR---LALALAR-- 75
                            90       100       110       120       130       140       150
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701      589 lpqEVDKEIFLLDEPTAGLDPFSRHQVWNLL-------KERKTDRVILFSTQFMDEAD-----ILADRKVFLSQG 651
Cdd:smart00382   76 ---KLKPDVLILDEITSLLDAEQEALLLLLEelrllllLKSEKNLTVILTTNDEKDLGpallrRRFDRRIVLLLI 147
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
1268-1436 2.36e-07

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 53.56  E-value: 2.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSgggDALEF--------LGYCPQENALWPNlTVRQH 1339
Cdd:PRK10247   25 NISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGE---DISTLkpeiyrqqVSYCAQTPTLFGD-TVYDN 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1340 LEVYAAVKGlrKGDAEVAITRLVDALKLQDQ-LKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQ 1418
Cdd:PRK10247  101 LIFPWQIRN--QQPDPAIFLDDLERFALPDTiLTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKHNVNE 178
                         170
                  ....*....|....*...
gi 6005701   1419 AIRATFRNTERGALLTTH 1436
Cdd:PRK10247  179 IIHRYVREQNIAVLWVTH 196
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
480-653 3.02e-07

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 53.17  E-value: 3.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYkgkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNK-LSEMADLENLSK 558
Cdd:PRK09493    2 IEFKNVSKHF----GPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKvNDPKVDERLIRQ 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    559 LTGVC-------PQ----SNVQFDFLTVRENLR---------LFAKI-----KGILPQE----------------VDKEI 597
Cdd:PRK09493   78 EAGMVfqqfylfPHltalENVMFGPLRVRGASKeeaekqareLLAKVglaerAHHYPSElsggqqqrvaiaralaVKPKL 157
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701    598 FLLDEPTAGLDPFSRHQVWNLLK---ERKTDRVILfsTQFMDEADILADRKVFLSQGKL 653
Cdd:PRK09493  158 MLFDEPTSALDPELRHEVLKVMQdlaEEGMTMVIV--THEIGFAEKVASRLIFIDKGRI 214
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
476-653 3.27e-07

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 55.03  E-value: 3.27e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   476 GKEAIRIRNVTkeYKGkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNnklsemADLEN 555
Cdd:COG3845  254 GEVVLEVENLS--VRD-DRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDG------EDITG 324
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   556 LS-----KL-----------TGVCPQsnvqfdfLTVRENL---------------------RLFAK-------IKG---- 587
Cdd:COG3845  325 LSprerrRLgvayipedrlgRGLVPD-------MSVAENLilgryrrppfsrggfldrkaiRAFAEelieefdVRTpgpd 397
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   588 --------------ILPQEVDKE--IFLLDEPTAGLDPFSRHQVWNLLKERKtDR---VILFSTQfMDEADILADRKVFL 648
Cdd:COG3845  398 tparslsggnqqkvILARELSRDpkLLIAAQPTRGLDVGAIEFIHQRLLELR-DAgaaVLLISED-LDEILALSDRIAVM 475

                 ....*
gi 6005701   649 SQGKL 653
Cdd:COG3845  476 YEGRI 480
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
1261-1459 3.31e-07

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 54.74  E-value: 3.31e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1261 KNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS--GGGDALEFL----------------- 1321
Cdd:PRK10982  259 LRQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKkiNNHNANEAInhgfalvteerrstgiy 338
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1322 GYCPQE-NALWPNltVRQHLEVYAAVKGLR-KGDAEVAItrlvDALKLQD-QLKSPVKTLSEGIKRKLCFVLSILGNPSV 1398
Cdd:PRK10982  339 AYLDIGfNSLISN--IRNYKNKVGLLDNSRmKSDTQWVI----DSMRVKTpGHRTQIGSLSGGNQQKVIIGRWLLTQPEI 412
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701   1399 VLLDEPSTGMDPEGQQQMWQAIrATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCI 1459
Cdd:PRK10982  413 LMLDEPTRGIDVGAKFEIYQLI-AELAKKDKGIIIISSEMPELLGITDRILVMSNGLVAGI 472
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
1268-1411 4.48e-07

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 54.35  E-value: 4.48e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsggGDALEfLGYCPQE-NALWPNLTvrqhleVYAAV 1346
Cdd:PRK11819  342 DLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-----GETVK-LAYVDQSrDALDPNKT------VWEEI 409
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701   1347 KG----LRKGDAEVAITRLVDA--LKLQDQLKsPVKTLSEGiKRK---LCFVLSILGNpsVVLLDEPSTGMDPE 1411
Cdd:PRK11819  410 SGgldiIKVGNREIPSRAYVGRfnFKGGDQQK-KVGVLSGG-ERNrlhLAKTLKQGGN--VLLLDEPTNDLDVE 479
GguA NF040905
sugar ABC transporter ATP-binding protein;
481-531 4.62e-07

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 54.41  E-value: 4.62e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 6005701    481 RIRNVTKEYKGkpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSG 531
Cdd:NF040905    3 EMRGITKTFPG----VKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSG 49
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
597-667 4.79e-07

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 53.97  E-value: 4.79e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701    597 IFLLDEPTAGLDPFSRHQVWNLLKERKTD-RVILFSTQFMDEADILADRKVFLSQGKLKCAGSSLFLKKKWG 667
Cdd:NF000106  165 VLYLDEPTTGLDPRTRNEVWDEVRSMVRDgATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVG 236
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
1260-1470 4.86e-07

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 54.73  E-value: 4.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1260 RKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSgggDALEF--------LGYCPQENALW 1331
Cdd:TIGR00958  491 RPDVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGV---PLVQYdhhylhrqVALVGQEPVLF 567
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1332 pNLTVRQHLevyaaVKGLRKG-DAEV-AITRLVDALKLQDQLKSPVKT--------LSEGIKRKLCFVLSILGNPSVVLL 1401
Cdd:TIGR00958  568 -SGSVRENI-----AYGLTDTpDEEImAAAKAANAHDFIMEFPNGYDTevgekgsqLSGGQKQRIAIARALVRKPRVLIL 641
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701    1402 DEPSTGMDPEGQQQMWQAIRAtfrnTERGALLTTHYMAEAEAvCDRVAIMVSGRLRCIGSIQHLKSKFG 1470
Cdd:TIGR00958  642 DEATSALDAECEQLLQESRSR----ASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLMEDQG 705
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
1274-1409 6.07e-07

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 54.02  E-value: 6.07e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1274 RKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQ---------VL--LKGSGGGDALEFLgycpQENalwpNLTVR---QH 1339
Cdd:COG1245   97 KKGKVTGILGPNGIGKSTALKILSGELKPNLGDydeepswdeVLkrFRGTELQDYFKKL----ANG----EIKVAhkpQY 168
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701  1340 LEVYA-AVKG-----LRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMD 1409
Cdd:COG1245  169 VDLIPkVFKGtvrelLEKVDERGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLD 244
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
478-594 6.54e-07

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 52.51  E-value: 6.54e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    478 EAIRIRNVTKEY----------------KGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVT 541
Cdd:PRK13546    3 VSVNIKNVTKEYriyrtnkermkdalipKHKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVD 82
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 6005701    542 iYNNKLSEMADLENLS-KLTGVcpqSNVQFDFLTVRENLRlfaKIKGILPQEVD 594
Cdd:PRK13546   83 -RNGEVSVIAISAGLSgQLTGI---ENIEFKMLCMGFKRK---EIKAMTPKIIE 129
cbiO PRK13642
energy-coupling factor transporter ATPase;
480-661 7.69e-07

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 52.40  E-value: 7.69e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYKGKPDkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEmADLENLSKL 559
Cdd:PRK13642    5 LEVENLVFKYEKESD-VNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTA-ENVWNLRRK 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    560 TGVCPQS-NVQFDFLTVRENLRLFAKIKGILPQEVDK----------------------------------------EIF 598
Cdd:PRK13642   83 IGMVFQNpDNQFVGATVEDDVAFGMENQGIPREEMIKrvdeallavnmldfktreparlsggqkqrvavagiialrpEII 162
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701    599 LLDEPTAGLDPFSRHQVWNLLKERKTDR--VILFSTQFMDEAdILADRKVFLSQGKL--KCAGSSLF 661
Cdd:PRK13642  163 ILDESTSMLDPTGRQEIMRVIHEIKEKYqlTVLSITHDLDEA-ASSDRILVMKAGEIikEAAPSELF 228
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
1265-1455 7.95e-07

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 53.68  E-value: 7.95e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGdTKPTA---GQVL-----LKGSGGGDALEF-LGYCPQENALWPNLT 1335
Cdd:TIGR02633   16 ALDGIDLEVRPGECVGLCGENGAGKSTLMKILSG-VYPHGtwdGEIYwsgspLKASNIRDTERAgIVIIHQELTLVPELS 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1336 VRQHL----EVyaAVKGLRKGDAevAITRLVDALKLQDQLKS-----PVKTLSEGIKRKLCFVLSILGNPSVVLLDEPST 1406
Cdd:TIGR02633   95 VAENIflgnEI--TLPGGRMAYN--AMYLRAKNLLRELQLDAdnvtrPVGDYGGGQQQLVEIAKALNKQARLLILDEPSS 170
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 6005701    1407 GMDPEGQQQMWQAIRaTFRNTERGALLTTHYMAEAEAVCDRVAIMVSGR 1455
Cdd:TIGR02633  171 SLTEKETEILLDIIR-DLKAHGVACVYISHKLNEVKAVCDTICVIRDGQ 218
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
497-657 8.08e-07

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 52.28  E-value: 8.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    497 EALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLS---------EMADLENL----SKLTGVC 563
Cdd:PRK10619   19 EVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINlvrdkdgqlKVADKNQLrllrTRLTMVF 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    564 PQSNVqFDFLTVREN--------------------LRLFAKI------KGILP--------QEV--------DKEIFLLD 601
Cdd:PRK10619   99 QHFNL-WSHMTVLENvmeapiqvlglskqeareraVKYLAKVgideraQGKYPvhlsggqqQRVsiaralamEPEVLLFD 177
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    602 EPTAGLDPFSRHQVWNLLK----ERKTDRVIlfsTQFMDEADILADRKVFLSQGKLKCAG 657
Cdd:PRK10619  178 EPTSALDPELVGEVLRIMQqlaeEGKTMVVV---THEMGFARHVSSHVIFLHQGKIEEEG 234
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
1253-1311 8.20e-07

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 52.48  E-value: 8.20e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701   1253 RKGCFsKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG 1311
Cdd:PRK15112   17 RTGWF-RRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDD 74
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
499-657 8.47e-07

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 53.31  E-value: 8.47e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    499 LKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLsEMADLENLSKLTGVCPQ-SNVQFDFlTVRE 577
Cdd:PRK09536   19 LDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDV-EALSARAASRRVASVPQdTSLSFEF-DVRQ 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    578 NLRL--------FAKI-------------KGILPQEVDKEI-----------------------FLLDEPTAGLDpfSRH 613
Cdd:PRK09536   97 VVEMgrtphrsrFDTWtetdraaverameRTGVAQFADRPVtslsggerqrvllaralaqatpvLLLDEPTASLD--INH 174
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 6005701    614 QVWNLLKERK---TDRVILFSTQFMDEADILADRKVFLSQGKLKCAG 657
Cdd:PRK09536  175 QVRTLELVRRlvdDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAG 221
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
1262-1449 9.46e-07

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 52.09  E-value: 9.46e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1262 NKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVI--TGDTKPTA---GQVLLKGS----GGGDALEF---LGYCPQENA 1329
Cdd:PRK14243   22 SFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFnrLNDLIPGFrveGKVTFHGKnlyaPDVDPVEVrrrIGMVFQKPN 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1330 LWPNlTVRQHLEVYAAVKGLrKGDAEVAITRLVDALKLQDQLKSPVKT----LSEGIKRKLCFVLSILGNPSVVLLDEPS 1405
Cdd:PRK14243  102 PFPK-SIYDNIAYGARINGY-KGDMDELVERSLRQAALWDEVKDKLKQsglsLSGGQQQRLCIARAIAVQPEVILMDEPC 179
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 6005701   1406 TGMDPEGQQQMWQAIRATFRntERGALLTTHYMAEAEAVCDRVA 1449
Cdd:PRK14243  180 SALDPISTLRIEELMHELKE--QYTIIIVTHNMQQAARVSDMTA 221
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
480-560 1.00e-06

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 51.50  E-value: 1.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPD-------------------KIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSG--LSVPTKG 538
Cdd:COG2401    8 FVLMRVTKVYSSVLDlservaivleafgvelrvvERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGalKGTPVAG 87
                         90       100
                 ....*....|....*....|...
gi 6005701   539 SVTIYNNKL-SEMADLENLSKLT 560
Cdd:COG2401   88 CVDVPDNQFgREASLIDAIGRKG 110
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
1273-1409 1.15e-06

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 53.27  E-value: 1.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1273 VRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQ---------VL--LKGSGGGDALEFL-------GYCPQENALWPNl 1334
Cdd:PRK13409   96 PKEGKVTGILGPNGIGKTTAVKILSGELIPNLGDyeeepswdeVLkrFRGTELQNYFKKLyngeikvVHKPQYVDLIPK- 174
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1335 tvrqhlevyaAVKG-----LRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMD 1409
Cdd:PRK13409  175 ----------VFKGkvrelLKKVDERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLD 244
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
1262-1413 1.17e-06

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 51.91  E-value: 1.17e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1262 NKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS-----GGGDALEFLGYCPQeNALWP-NLT 1335
Cdd:PRK10253   19 KYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEhiqhyASKEVARRIGLLAQ-NATTPgDIT 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1336 VRQ--------HLEVYAAvkgLRKGDAEvAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTG 1407
Cdd:PRK10253   98 VQElvargrypHQPLFTR---WRKEDEE-AVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTW 173

                  ....*.
gi 6005701   1408 MDPEGQ 1413
Cdd:PRK10253  174 LDISHQ 179
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
476-659 1.45e-06

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 51.59  E-value: 1.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    476 GKEAIRIRNVTKEYKGKPDKiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGL------SVPTKGSVTIYNNKLSE 549
Cdd:PRK14246    4 GKSAEDVFNISRLYLYINDK-AILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLieiydsKIKVDGKVLYFGKDIFQ 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    550 MaDLENLSKLTGVCPQSNVQFDFLTVRENLRLFAK---------IKGILPQEVDK------------------------- 595
Cdd:PRK14246   83 I-DAIKLRKEVGMVFQQPNPFPHLSIYDNIAYPLKshgikekreIKKIVEECLRKvglwkevydrlnspasqlsggqqqr 161
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701    596 -----------EIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADILADRKVFLSQGKLKCAGSS 659
Cdd:PRK14246  162 ltiaralalkpKVLLMDEPTSMIDIVNSQAIEKLITELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSS 236
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
1263-1411 1.75e-06

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 52.65  E-value: 1.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1263 KIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsggGDALEfLGYCPQENA-LWPNLTVrqhle 1341
Cdd:PRK11147  332 KQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHC-----GTKLE-VAYFDQHRAeLDPEKTV----- 400
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701   1342 vyaaVKGLRKGDAEVAIT-RLVDALK-LQDQL------KSPVKTLSEGIKRKLcFVLSILGNPSVVL-LDEPSTGMDPE 1411
Cdd:PRK11147  401 ----MDNLAEGKQEVMVNgRPRHVLGyLQDFLfhpkraMTPVKALSGGERNRL-LLARLFLKPSNLLiLDEPTNDLDVE 474
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
1245-1461 1.89e-06

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 51.77  E-value: 1.89e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1245 LRKEYAGKRKgcfskrknkiATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGD-------- 1316
Cdd:PRK11650    9 VRKSYDGKTQ----------VIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNElepadrdi 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1317 ALEFLGYcpqenALWPNLTVRQHLEvYA-AVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGN 1395
Cdd:PRK11650   79 AMVFQNY-----ALYPHMSVRENMA-YGlKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVRE 152
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701   1396 PSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:PRK11650  153 PAVFLFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGT 218
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
1283-1411 2.48e-06

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 49.87  E-value: 2.48e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1283 GHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGD-ALEFLGYCPQENALWPNLTVRQHLEVYAAVKglrkgDAEVAITRL 1361
Cdd:PRK13541   33 GANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNiAKPYCTYIGHNLGLKLEMTVFENLKFWSEIY-----NSAETLYAA 107
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 6005701   1362 VDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPE 1411
Cdd:PRK13541  108 IHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKE 157
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
486-587 2.53e-06

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 49.80  E-value: 2.53e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   486 TKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADlENLSKLTGVCPQ 565
Cdd:cd03231    3 ADELTCERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRD-SIARGLLYLGHA 81
                         90       100
                 ....*....|....*....|..
gi 6005701   566 SNVQfDFLTVRENLRLFAKIKG 587
Cdd:cd03231   82 PGIK-TTLSVLENLRFWHADHS 102
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
480-542 2.70e-06

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 52.34  E-value: 2.70e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6005701    480 IRIRNVTKEYKGKPDkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI 542
Cdd:PTZ00265  383 IQFKNVRFHYDTRKD-VEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIII 444
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
1269-1403 2.99e-06

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 51.72  E-value: 2.99e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1269 VSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLkgsgGGDALEflgycpQENALWpnltVRQHlevYAAV-- 1346
Cdd:COG4615  351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILL----DGQPVT------ADNREA----YRQL---FSAVfs 413
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701  1347 --------KGLRKGDAEVAITRLVDALKLQDQLK------SPVKtLSEGIKRKLCFVLSILGNPSVVLLDE 1403
Cdd:COG4615  414 dfhlfdrlLGLDGEADPARARELLERLELDHKVSvedgrfSTTD-LSQGQRKRLALLVALLEDRPILVFDE 483
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
480-554 3.17e-06

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 49.87  E-value: 3.17e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701    480 IRIRNVTKEYKGKPdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLE 554
Cdd:PRK10908    2 IRFEHVSKAYLGGR---QALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNRE 73
YjeQ_EngC cd01854
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; ...
493-531 3.41e-06

Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; YjeQ (YloQ in Bacillus subtilis) is a ribosomal small subunit-dependent GTPase; hence also known as RsgA. YjeQ is a late-stage ribosomal biogenesis factor involved in the 30S subunit maturation, and it represents a protein family whose members are broadly conserved in bacteria and have been shown to be essential to the growth of E. coli and B. subtilis. Proteins of the YjeQ family contain all sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases. All YjeQ family proteins display a unique domain architecture, which includes an N-terminal OB-fold RNA-binding domain, the central permuted GTPase domain, and a zinc knuckle-like C-terminal cysteine domain.


Pssm-ID: 206747 [Multi-domain]  Cd Length: 211  Bit Score: 49.70  E-value: 3.41e-06
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 6005701   493 PDKIEALKDLVfdiyEGQITAILGHSGAGKSTLLNILSG 531
Cdd:cd01854   73 GEGLDELRELL----KGKTSVLVGQSGVGKSTLLNALLP 107
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
1265-1298 3.65e-06

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 51.47  E-value: 3.65e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITG 1298
Cdd:PRK13549   20 ALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSG 53
PLN03140 PLN03140
ABC transporter G family member; Provisional
494-596 3.66e-06

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 52.16  E-value: 3.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    494 DKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVP--TKGSVTIYNNKLSEmadlENLSKLTGVCPQSNVQFD 571
Cdd:PLN03140  891 DRLQLLREVTGAFRPGVLTALMGVSGAGKTTLMDVLAGRKTGgyIEGDIRISGFPKKQ----ETFARISGYCEQNDIHSP 966
                          90       100
                  ....*....|....*....|....*
gi 6005701    572 FLTVRENLRLFAKIKgiLPQEVDKE 596
Cdd:PLN03140  967 QVTVRESLIYSAFLR--LPKEVSKE 989
cbiO PRK13649
energy-coupling factor transporter ATPase;
1268-1456 3.90e-06

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 50.51  E-value: 3.90e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG------SGGGDALEF---LGYCPQ--ENALWPNlTV 1336
Cdd:PRK13649   25 DVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDtlitstSKNKDIKQIrkkVGLVFQfpESQLFEE-TV 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1337 RQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQL--KSPVKtLSEGIKRKLCfVLSILG-NPSVVLLDEPSTGMDPEGQ 1413
Cdd:PRK13649  104 LKDVAFGPQNFGVSQEEAEALAREKLALVGISESLfeKNPFE-LSGGQMRRVA-IAGILAmEPKILVLDEPTAGLDPKGR 181
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 6005701   1414 QQMWQairaTFRNTERGAL---LTTHYMAEAEAVCDRVAIMVSGRL 1456
Cdd:PRK13649  182 KELMT----LFKKLHQSGMtivLVTHLMDDVANYADFVYVLEKGKL 223
RsgA COG1162
Ribosome biogenesis GTPase RsgA [Translation, ribosomal structure and biogenesis];
496-531 4.48e-06

Ribosome biogenesis GTPase RsgA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440776 [Multi-domain]  Cd Length: 300  Bit Score: 50.50  E-value: 4.48e-06
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 6005701   496 IEALKDLVfdiyEGQITAILGHSGAGKSTLLNILSG 531
Cdd:COG1162  157 LDELRELL----KGKTSVLVGQSGVGKSTLINALLP 188
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
505-644 4.78e-06

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 49.71  E-value: 4.78e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   505 DIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLS----------EMADLENLSKLT-GVCPQSNVQFDFL 573
Cdd:cd03237   21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVSykpqyikadyEGTVRDLLSSITkDFYTHPYFKTEIA 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   574 TVrenlrlfAKIKGILPQEV-------------------DKEIFLLDEPTAGLDPFSRhqvwnLLKERKTDRVILF--ST 632
Cdd:cd03237  101 KP-------LQIEQILDREVpelsggelqrvaiaaclskDADIYLLDEPSAYLDVEQR-----LMASKVIRRFAENneKT 168
                        170
                 ....*....|....*..
gi 6005701   633 QFMDEADI-----LADR 644
Cdd:cd03237  169 AFVVEHDIimidyLADR 185
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
509-587 7.30e-06

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 49.01  E-value: 7.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    509 GQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMaDLENLSKL----TGVCPQSNVQFDFLTVRENLRLFAK 584
Cdd:PRK10584   36 GETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQM-DEEARAKLrakhVGFVFQSFMLIPTLNALENVELPAL 114

                  ...
gi 6005701    585 IKG 587
Cdd:PRK10584  115 LRG 117
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
1235-1311 9.05e-06

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 49.58  E-value: 9.05e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701   1235 DEKPVIIASCLRKEYAGKRkGCFSKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG 1311
Cdd:PRK11308    1 SQQPLLQAIDLKKHYPVKR-GLFKPERLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQG 76
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
478-548 9.25e-06

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 50.17  E-value: 9.25e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   478 EAIRIRNVtkeykgkPDKIEalKDLV-------FDIY------EGQITAILGHSGAGKSTLLNILSGLSVPTKGsvtIYN 544
Cdd:COG1245   64 DAISIVNL-------PEELE--EDPVhrygengFRLYglpvpkKGKVTGILGPNGIGKSTALKILSGELKPNLG---DYD 131

                 ....
gi 6005701   545 NKLS 548
Cdd:COG1245  132 EEPS 135
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
1268-1436 1.10e-05

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 50.49  E-value: 1.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKP---TAGQVLLKGSGGGDALE-FLGYCPQENALWPNLTVRQHLEVY 1343
Cdd:TIGR00956  781 NVDGWVKPGTLTALMGASGAGKTTLLNVLAERVTTgviTGGDRLVNGRPLDSSFQrSIGYVQQQDLHLPTSTVRESLRFS 860
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1344 AAvkgLRKgDAEVAIT---RLVDA----LKLQDQLKSPVKTLSEGI----KRKLCFVLSILGNP-SVVLLDEPSTGMDPE 1411
Cdd:TIGR00956  861 AY---LRQ-PKSVSKSekmEYVEEviklLEMESYADAVVGVPGEGLnveqRKRLTIGVELVAKPkLLLFLDEPTSGLDSQ 936
                          170       180
                   ....*....|....*....|....*
gi 6005701    1412 GQQQMWQAIRATfRNTERGALLTTH 1436
Cdd:TIGR00956  937 TAWSICKLMRKL-ADHGQAILCTIH 960
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
480-631 1.48e-05

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 48.70  E-value: 1.48e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   480 IRIRNVTKEYKGKPDKIeaLKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLsVPTKGSVTIYNNKLSEMAdLENLSKL 559
Cdd:cd03289    3 MTVKDLTAKYTEGGNAV--LENISFSISPGQRVGLLGRTGSGKSTLLSAFLRL-LNTEGDIQIDGVSWNSVP-LQKWRKA 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   560 TGVCPQSNVQFDFlTVRENLRLFAK--------------IKGILPQEVDK------------------------------ 595
Cdd:cd03289   79 FGVIPQKVFIFSG-TFRKNLDPYGKwsdeeiwkvaeevgLKSVIEQFPGQldfvlvdggcvlshghkqlmclarsvlska 157
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 6005701   596 EIFLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFS 631
Cdd:cd03289  158 KILLLDEPSAHLDPITYQVIRKTLKQAFADCTVILS 193
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
482-631 1.60e-05

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 49.91  E-value: 1.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     482 IRNVTKEYKGKPDKIeaLKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLsVPTKGSVTIYNNKLSEMAdLENLSKLTG 561
Cdd:TIGR01271 1220 VQGLTAKYTEAGRAV--LQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRL-LSTEGEIQIDGVSWNSVT-LQTWRKAFG 1295
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     562 VCPQSNVQFDFlTVRENLRLFAK--------------IKGILPQEVDK------------------------------EI 597
Cdd:TIGR01271 1296 VIPQKVFIFSG-TFRKNLDPYEQwsdeeiwkvaeevgLKSVIEQFPDKldfvlvdggyvlsnghkqlmclarsilskaKI 1374
                          170       180       190
                   ....*....|....*....|....*....|....
gi 6005701     598 FLLDEPTAGLDPFSRHQVWNLLKERKTDRVILFS 631
Cdd:TIGR01271 1375 LLLDEPSAHLDPVTLQIIRKTLKQSFSNCTVILS 1408
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
471-542 1.78e-05

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 49.35  E-value: 1.78e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6005701    471 PPEFQGKEAIRIRNVTKEYKgkpDKIeALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI 542
Cdd:PRK11819  316 PGPRLGDKVIEAENLSKSFG---DRL-LIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI 383
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
477-530 1.96e-05

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 49.25  E-value: 1.96e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 6005701    477 KEAIRIRNVTKEYKGKpdKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILS 530
Cdd:PRK11176  339 KGDIEFRNVTFTYPGK--EVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLT 390
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
1253-1470 2.09e-05

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 49.56  E-value: 2.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1253 RKGCFSKRKNKIATRN-VSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSgggdalefLGYCPQEnALW 1331
Cdd:TIGR00957  640 HNATFTWARDLPPTLNgITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS--------VAYVPQQ-AWI 710
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1332 PNLTVRQHLEVYAAVKGLRKGDAEVAITRLVD--ALKLQDQLKSPVK--TLSEGIKRKLCFVLSILGNPSVVLLDEPSTG 1407
Cdd:TIGR00957  711 QNDSLRENILFGKALNEKYYQQVLEACALLPDleILPSGDRTEIGEKgvNLSGGQKQRVSLARAVYSNADIYLFDDPLSA 790
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701    1408 MDPEGQQQMWQAI---RATFRNTERgaLLTTHYMAEAEAVcDRVAIMVSGRLRCIGSIQHLKSKFG 1470
Cdd:TIGR00957  791 VDAHVGKHIFEHVigpEGVLKNKTR--ILVTHGISYLPQV-DVIIVMSGGKISEMGSYQELLQRDG 853
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
1267-1409 2.65e-05

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 49.14  E-value: 2.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVllKGSGGgdalefLGYCPQENALWPNlTVRQHLevyaaV 1346
Cdd:TIGR01271  443 KNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKI--KHSGR------ISFSPQTSWIMPG-TIKDNI-----I 508
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6005701    1347 KGLRKGdaEVAITRLVDALKLQDQL-KSPVK----------TLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMD 1409
Cdd:TIGR01271  509 FGLSYD--EYRYTSVIKACQLEEDIaLFPEKdktvlgeggiTLSGGQRARISLARAVYKDADLYLLDSPFTHLD 580
RsgA_GTPase pfam03193
RsgA GTPase; RsgA (also known as EngC and YjeQ) represents a protein family whose members are ...
493-531 2.68e-05

RsgA GTPase; RsgA (also known as EngC and YjeQ) represents a protein family whose members are broadly conserved in bacteria and are indispensable for growth. The GTPase domain of RsgA is very similar to several P-loop GTPases, but differs in having a circular permutation of the GTPase structure described by a G4-G1-G3 pattern.


Pssm-ID: 427191 [Multi-domain]  Cd Length: 174  Bit Score: 46.38  E-value: 2.68e-05
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 6005701     493 PDKIEALKDLVfdiyEGQITAILGHSGAGKSTLLNILSG 531
Cdd:pfam03193   94 GEGIEALKELL----KGKTTVLAGQSGVGKSTLLNALLP 128
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
492-621 3.18e-05

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 47.78  E-value: 3.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    492 KPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLSK-----------LT 560
Cdd:PRK15079   30 PPKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWRAVrsdiqmifqdpLA 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    561 GVCPQSNV-------------QFDFLTVRENLRLFAKIKGILPQEVDK-----------------------EIFLLDEPT 604
Cdd:PRK15079  110 SLNPRMTIgeiiaeplrtyhpKLSRQEVKDRVKAMMLKVGLLPNLINRyphefsggqcqrigiaralilepKLIICDEPV 189
                         170
                  ....*....|....*..
gi 6005701    605 AGLDPFSRHQVWNLLKE 621
Cdd:PRK15079  190 SALDVSIQAQVVNLLQQ 206
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
478-535 3.56e-05

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 48.27  E-value: 3.56e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701    478 EAIRIRNVtkeykgkPDKIEalKDLV-------FDIY------EGQITAILGHSGAGKSTLLNILSGLSVP 535
Cdd:PRK13409   64 DAISIVNL-------PEELE--EEPVhrygvngFKLYglpipkEGKVTGILGPNGIGKTTAVKILSGELIP 125
PLN03211 PLN03211
ABC transporter G-25; Provisional
509-600 3.90e-05

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 48.34  E-value: 3.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    509 GQITAILGHSGAGKSTLLNILSGL--SVPTKGSVTIYNNKLSemadlENLSKLTGVCPQSNVQFDFLTVRENLRLFAKIK 586
Cdd:PLN03211   94 GEILAVLGPSGSGKSTLLNALAGRiqGNNFTGTILANNRKPT-----KQILKRTGFVTQDDILYPHLTVRETLVFCSLLR 168
                          90
                  ....*....|....
gi 6005701    587 giLPQEVDKEIFLL 600
Cdd:PLN03211  169 --LPKSLTKQEKIL 180
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
499-592 4.01e-05

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 46.63  E-value: 4.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    499 LKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADlENLSKLTGVCPQSNVQF-DflTVRE 577
Cdd:PRK10247   23 LNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKP-EIYRQQVSYCAQTPTLFgD--TVYD 99
                          90
                  ....*....|....*
gi 6005701    578 NLRLFAKIKGILPQE 592
Cdd:PRK10247  100 NLIFPWQIRNQQPDP 114
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
504-579 4.41e-05

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 46.91  E-value: 4.41e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701    504 FDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADlENLSKLTGVCPQSNVQ-FDFLTVRENL 579
Cdd:PRK11300   26 LEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPG-HQIARMGVVRTFQHVRlFREMTVIENL 101
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
1267-1419 4.77e-05

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 47.16  E-value: 4.77e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVllKGSGGgdalefLGYCPQENALWPNlTVRQHLEVYAAV 1346
Cdd:cd03291   54 KNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKI--KHSGR------ISFSSQFSWIMPG-TIKENIIFGVSY 124
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701  1347 KGLRKGDAEVAITRLVDALKLQDQLKSPVK----TLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQA 1419
Cdd:cd03291  125 DEYRYKSVVKACQLEEDITKFPEKDNTVLGeggiTLSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTEKEIFES 201
GguA NF040905
sugar ABC transporter ATP-binding protein;
1265-1298 4.89e-05

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 47.86  E-value: 4.89e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITG 1298
Cdd:NF040905   16 ALDDVNLSVREGEIHALCGENGAGKSTLMKVLSG 49
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
1235-1291 5.64e-05

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 47.76  E-value: 5.64e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701  1235 DEKPVIIASCLRKEYAGKRkGCFSKRKNKI-ATRNVSFCVRKGEVLGLLGHNGAGKST 1291
Cdd:COG4172  271 DAPPLLEARDLKVWFPIKR-GLFRRTVGHVkAVDGVSLTLRRGETLGLVGESGSGKST 327
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
1256-1410 5.86e-05

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 47.66  E-value: 5.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1256 CFSKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSgggdaleflgycPQENALWPNLt 1335
Cdd:PRK10522  329 TFAYQDNGFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGK------------PVTAEQPEDY- 395
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1336 vRQHlevYAAV-------KGLRKGDAEVAITRLVDA----LKLQDQLK------SPVKtLSEGIKRKLCFVLSILGNPSV 1398
Cdd:PRK10522  396 -RKL---FSAVftdfhlfDQLLGPEGKPANPALVEKwlerLKMAHKLEledgriSNLK-LSKGQKKRLALLLALAEERDI 470
                         170
                  ....*....|..
gi 6005701   1399 VLLDEPSTGMDP 1410
Cdd:PRK10522  471 LLLDEWAADQDP 482
hmuV PRK13547
heme ABC transporter ATP-binding protein;
499-643 6.80e-05

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 46.36  E-value: 6.80e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    499 LKDLVFDIYEGQITAILGHSGAGKSTLLNILSG--------LSVPTKGSVTIYNNKLSEMaDLENLSKLTGVCPQ-SNVQ 569
Cdd:PRK13547   17 LRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGdltgggapRGARVTGDVTLNGEPLAAI-DAPRLARLRAVLPQaAQPA 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    570 FDFlTVRENLRL-------------------------------------------------FAKIKGIL-PQE---VDKE 596
Cdd:PRK13547   96 FAF-SAREIVLLgrypharragalthrdgeiawqalalagatalvgrdvttlsggelarvqFARVLAQLwPPHdaaQPPR 174
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701    597 IFLLDEPTAGLDPFSRHQV----------WNL----------LKERKTDRVILFStqfmdEADILAD 643
Cdd:PRK13547  175 YLLLDEPTAALDLAHQHRLldtvrrlardWNLgvlaivhdpnLAARHADRIAMLA-----DGAIVAH 236
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
480-540 7.30e-05

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 46.22  E-value: 7.30e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701    480 IRIRNVTKEYK-----GKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSV 540
Cdd:PRK10419    4 LNVSGLSHHYAhgglsGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNV 69
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
1248-1471 9.29e-05

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 46.88  E-value: 9.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1248 EYAGKRKGCFskrknkiatrNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGD-ALEFL----G 1322
Cdd:PRK13657  343 SYDNSRQGVE----------DVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTvTRASLrrniA 412
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1323 YCPQENALWpNLTVRQHLEVyaavkGlrKGDAEVAitRLVDALKLQDQL----KSPVK----------TLSEGIKRKLCF 1388
Cdd:PRK13657  413 VVFQDAGLF-NRSIEDNIRV-----G--RPDATDE--EMRAAAERAQAHdfieRKPDGydtvvgergrQLSGGERQRLAI 482
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1389 VLSILGNPSVVLLDEPSTGMDPEGQQQMWQAI------RATFRNTERgalLTThyMAEAeavcDRVAIMVSGRLRCIGSI 1462
Cdd:PRK13657  483 ARALLKDPPILILDEATSALDVETEAKVKAALdelmkgRTTFIIAHR---LST--VRNA----DRILVFDNGRVVESGSF 553

                  ....*....
gi 6005701   1463 QHLKSKFGK 1471
Cdd:PRK13657  554 DELVARGGR 562
PRK00098 PRK00098
GTPase RsgA; Reviewed
496-536 9.95e-05

GTPase RsgA; Reviewed


Pssm-ID: 234631 [Multi-domain]  Cd Length: 298  Bit Score: 46.35  E-value: 9.95e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 6005701    496 IEALKDLVfdiyEGQITAILGHSGAGKSTLLN-ILSGLSVPT 536
Cdd:PRK00098  155 LDELKPLL----AGKVTVLAGQSGVGKSTLLNaLAPDLELKT 192
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
498-643 1.04e-04

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 44.62  E-value: 1.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   498 ALKDLVFDIYEGQITAILGHSGAGKSTLLN----------ILSGLSVPTKgSVTIYNNKLSEMADLeNLSKLTGVCPQSN 567
Cdd:cd03238   10 NLQNLDVSIPLNVLVVVTGVSGSGKSTLVNeglyasgkarLISFLPKFSR-NKLIFIDQLQFLIDV-GLGYLTLGQKLST 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   568 vqfdfLTVRENLRLfaKIKGILPQEVDKEIFLLDEPTAGLDPFSRHQVWNLLKE--RKTDRVILF--STQFMDEADILAD 643
Cdd:cd03238   88 -----LSGGELQRV--KLASELFSEPPGTLFILDEPSTGLHQQDINQLLEVIKGliDLGNTVILIehNLDVLSSADWIID 160
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
500-577 1.13e-04

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 45.75  E-value: 1.13e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701    500 KDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLEnLSKLTGVCPQSNVQFDFLTVRE 577
Cdd:PRK10253   24 ENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKE-VARRIGLLAQNATTPGDITVQE 100
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
482-542 1.44e-04

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 45.87  E-value: 1.44e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701    482 IRNVTKEYkGKPDKIEalkDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI 542
Cdd:PRK11432    9 LKNITKRF-GSNTVID---NLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFI 65
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
1267-1421 1.55e-04

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 45.07  E-value: 1.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1267 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG----SGGGDAL-EFLGYCPQENALWPNLTVRQhLe 1341
Cdd:COG4604   18 DDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGldvaTTPSRELaKRLAILRQENHINSRLTVRE-L- 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701  1342 V----YAAVKG-LRKGDaEVAITRLVDALKLQDQLKSPVKTLSEGiKRKLCFVLSILG-NPSVVLLDEPSTGMDPEGQQQ 1415
Cdd:COG4604   96 VafgrFPYSKGrLTAED-REIIDEAIAYLDLEDLADRYLDELSGG-QRQRAFIAMVLAqDTDYVLLDEPLNNLDMKHSVQ 173

                 ....*.
gi 6005701  1416 MWQAIR 1421
Cdd:COG4604  174 MMKLLR 179
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
479-551 1.61e-04

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 46.25  E-value: 1.61e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6005701    479 AIRIRNVTKEYKGkpDKIeALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMA 551
Cdd:PRK10790  340 RIDIDNVSFAYRD--DNL-VLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLS 409
PLN03232 PLN03232
ABC transporter C family member; Provisional
479-584 1.94e-04

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 46.51  E-value: 1.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    479 AIRIRNVTKEYKgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMAdLENLSK 558
Cdd:PLN03232 1234 SIKFEDVHLRYR--PGLPPVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFG-LTDLRR 1310
                          90       100
                  ....*....|....*....|....*.
gi 6005701    559 LTGVCPQSNVQFDFlTVRENLRLFAK 584
Cdd:PLN03232 1311 VLSIIPQSPVLFSG-TVRFNIDPFSE 1335
PTZ00243 PTZ00243
ABC transporter; Provisional
1263-1461 2.12e-04

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 46.31  E-value: 2.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1263 KIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSgggdalefLGYCPQEnALWPNLTVRQHLEV 1342
Cdd:PTZ00243  673 KVLLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVWAERS--------IAYVPQQ-AWIMNATVRGNILF 743
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1343 YaavkglrkgDAEVAiTRLVDALKLQD------QLKSPVKT--------LSEGIKRKLCFVLSILGNPSVVLLDEPSTGM 1408
Cdd:PTZ00243  744 F---------DEEDA-ARLADAVRVSQleadlaQLGGGLETeigekgvnLSGGQKARVSLARAVYANRDVYLLDDPLSAL 813
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 6005701   1409 DPE-GQQQMWQAIRATFRNTERgaLLTTHYMaEAEAVCDRVAIMVSGRLRCIGS 1461
Cdd:PTZ00243  814 DAHvGERVVEECFLGALAGKTR--VLATHQV-HVVPRADYVVALGDGRVEFSGS 864
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
1268-1309 2.25e-04

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 45.65  E-value: 2.25e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 6005701   1268 NVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLL 1309
Cdd:PRK15064   19 NISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSL 60
PLN03232 PLN03232
ABC transporter C family member; Provisional
1269-1468 2.29e-04

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 46.12  E-value: 2.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1269 VSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGS-----GGGDALEFLGYCPQENALWPNlTVRQHLEVY 1343
Cdd:PLN03232 1255 LSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCdvakfGLTDLRRVLSIIPQSPVLFSG-TVRFNIDPF 1333
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1344 AA------VKGLRKGDAEVAITRlvDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMW 1417
Cdd:PLN03232 1334 SEhndadlWEALERAHIKDVIDR--NPFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDVRTDSLIQ 1411
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 6005701   1418 QAIRATFRNTergALLTTHYMAEAEAVCDRVAIMVSGRLRCIGSIQHLKSK 1468
Cdd:PLN03232 1412 RTIREEFKSC---TMLVIAHRLNTIIDCDKILVLSSGQVLEYDSPQELLSR 1459
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
509-583 2.51e-04

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 44.45  E-value: 2.51e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6005701   509 GQITAILGHSGAGKSTLLNILSGLSvPTKGSVTIYNNKLSEMaDLENLSKLTGVCPQSNVQFDFLTVRENLRLFA 583
Cdd:COG4138   22 GELIHLIGPNGAGKSTLLARMAGLL-PGQGEILLNGRPLSDW-SAAELARHRAYLSQQQSPPFAMPVFQYLALHQ 94
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
1278-1404 2.63e-04

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 45.25  E-value: 2.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   1278 VLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALE--FL-------GYCPQENALWPNLTVRQHLEvYaavkG 1348
Cdd:PRK11144   26 ITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKgiCLppekrriGYVFQDARLFPHYKVRGNLR-Y----G 100
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701   1349 LRKGDAEvAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNPSVVLLDEP 1404
Cdd:PRK11144  101 MAKSMVA-QFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEP 155
GAAP_like cd10429
Golgi antiapoptotic protein; GAAP (or transmembrane BAX inhibitor motif containing 4) is a ...
266-373 3.03e-04

Golgi antiapoptotic protein; GAAP (or transmembrane BAX inhibitor motif containing 4) is a regulator of apoptosis that is related to the BAX inhibitor (BI)-1 like family of small transmembrane proteins, which have been shown to have an antiapoptotic effect either by stimulating the antiapoptotic function of Bcl-2, a well-characterized oncogene, or by inhibiting the proapoptotic effect of Bax, another member of the Bcl-2 family. Human GAAP has been linked to the modulation of intracellular fluxes of Ca(2+), by suppressing influx from the extracellular medium and reducing release from intracellular stores. A viral homolog (vaccinia virus vGAAP) acts similar to its human counterpart in inhibiting apoptosis.


Pssm-ID: 198411  Cd Length: 233  Bit Score: 44.13  E-value: 3.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   266 WLSWGLLYAGFIFIMALFLALVIRSTQFIILSGFmvvfSLFLLYGLSLVALAFLMSILVKKSFLTGLVVFLLTV--FWGC 343
Cdd:cd10429   67 WLFLISLIGSLILLIALYWKRHSHPVNLILLSLF----TLCEAYTVGLVVSFYDGKIVLQALILTLGVFVGLTAytFQTK 142
                         90       100       110
                 ....*....|....*....|....*....|
gi 6005701   344 LGFTSLYRHLPASLeWILSLLSPFAFMLGM 373
Cdd:cd10429  143 RDFSSFGALLFILL-WALILLALIFQFFPY 171
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
1253-1292 3.09e-04

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 45.47  E-value: 3.09e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 6005701   1253 RKGCFsKRK--NKIATRNVSFCVRKGEVLGLLGHNGAGKSTS 1292
Cdd:PRK15134  288 RKGIL-KRTvdHNVVVKNISFTLRPGETLGLVGESGSGKSTT 328
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
467-565 3.12e-04

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 45.27  E-value: 3.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    467 FEQAPPEFqgKEAIRIRNVTKEYKGKPdkieALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVtiynnK 546
Cdd:PRK15064  309 FEQDKKLH--RNALEVENLTKGFDNGP----LFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV-----K 377
                          90
                  ....*....|....*....
gi 6005701    547 LSEMADLenlskltGVCPQ 565
Cdd:PRK15064  378 WSENANI-------GYYAQ 389
NosY COG1277
ABC-type transport system involved in multi-copper enzyme maturation, permease component ...
213-340 3.71e-04

ABC-type transport system involved in multi-copper enzyme maturation, permease component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440888 [Multi-domain]  Cd Length: 201  Bit Score: 43.27  E-value: 3.71e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   213 SFIGQSGVITDLYLFSCIISFSSFIYY------ASVNVTRERKR--MKALMTMmGLRDSAF--------WLSWGLLYAgF 276
Cdd:COG1277   36 GGAASGFLGLGLALLASLFSLLSLLLPllapalGMDAISGERESgtLELLLTL-PISRWEIvlgkflgaLLVLLLALL-I 113
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701   277 IFIMALFLALVIRSTQFIILSGFMVVFSLFLLYGLSLVALAFLMSILVKK---SFLTGLVVFLLTVF 340
Cdd:COG1277  114 TFLLALLLGLLLFGSPPPDLGAILGFYLGLLLLGLAFLAIGLFISALTRNqivAAILAIALWLLLVI 180
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
467-608 4.68e-04

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 44.78  E-value: 4.68e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   467 FEQAPP--EFQGKEAIRIRNVTKEYKGKPDKIEAlkdlvFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIyN 544
Cdd:COG1245  327 FEVHAPrrEKEEETLVEYPDLTKSYGGFSLEVEG-----GEIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDE-D 400
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   545 NKLSemadlenlSKltgvcPQSnVQFDF-LTVRENLRLFAK-----------------IKGILPQEV------------- 593
Cdd:COG1245  401 LKIS--------YK-----PQY-ISPDYdGTVEEFLRSANTddfgssyykteiikplgLEKLLDKNVkdlsggelqrvai 466
                        170       180
                 ....*....|....*....|.
gi 6005701   594 ------DKEIFLLDEPTAGLD 608
Cdd:COG1245  467 aaclsrDADLYLLDEPSAHLD 487
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
509-577 5.43e-04

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 43.62  E-value: 5.43e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6005701    509 GQITAILGHSGAGKSTLLNILSGLSVPTKGSVtIYNNKLSEMADLENLSKLTGVCPQSNVQFDFLTVRE 577
Cdd:PRK10575   37 GKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEI-LLDAQPLESWSSKAFARKVAYLPQQLPAAEGMTVRE 104
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
499-585 6.38e-04

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 42.55  E-value: 6.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    499 LKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSemadleNLSK--LTGVCPQSNVQFDfLTVR 576
Cdd:PRK13541   16 LFDLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNIN------NIAKpyCTYIGHNLGLKLE-MTVF 88

                  ....*....
gi 6005701    577 ENLRLFAKI 585
Cdd:PRK13541   89 ENLKFWSEI 97
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
480-659 6.41e-04

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 43.46  E-value: 6.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    480 IRIRNVTKEYKGKpdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGS---VTIYNNKLSEMA----D 552
Cdd:PRK09984    5 IRVEKLAKTFNQH----QALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSAgshIELLGRTVQREGrlarD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    553 LENLSKLTGVCPQsnvQFDF---LTVREN---------------LRLFAKIK-------------------------GIL 589
Cdd:PRK09984   81 IRKSRANTGYIFQ---QFNLvnrLSVLENvligalgstpfwrtcFSWFTREQkqralqaltrvgmvhfahqrvstlsGGQ 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    590 PQEV--------DKEIFLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFST-QFMDEADILADRKVFLSQGKLKCAGSS 659
Cdd:PRK09984  158 QQRVaiaralmqQAKVILADEPIASLDPESARIVMDTLRDiNQNDGITVVVTlHQVDYALRYCERIVALRQGHVFYDGSS 237
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
483-542 6.64e-04

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 43.80  E-value: 6.64e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6005701    483 RNVTKEY---KG---KPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTI 542
Cdd:PRK11308    9 IDLKKHYpvkRGlfkPERLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYY 74
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
458-540 7.03e-04

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 44.29  E-value: 7.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701   458 DADPSFhdsfEQAPPEFQGKEAIRIRNVTKEYKGK-------PDKIEALKDLVFDIYEGQITAILGHSGAGKSTL-LNIL 529
Cdd:COG4172  258 AAEPRG----DPRPVPPDAPPLLEARDLKVWFPIKrglfrrtVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLgLALL 333
                         90
                 ....*....|.
gi 6005701   530 sGLsVPTKGSV 540
Cdd:COG4172  334 -RL-IPSEGEI 342
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
483-532 7.88e-04

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 43.76  E-value: 7.88e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 6005701    483 RNVTKEYKGkpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGL 532
Cdd:PRK13549    9 KNITKTFGG----VKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGV 54
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
480-546 1.15e-03

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 43.45  E-value: 1.15e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701    480 IRIRNVTKEYKGkpdkIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVtIYNNK 546
Cdd:PRK10762    5 LQLKGIDKAFPG----VKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSI-LYLGK 66
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
480-540 1.38e-03

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 42.41  E-value: 1.38e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701    480 IRIRNVTKEYKGKpdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSV 540
Cdd:PRK09544    5 VSLENVSVSFGQR----RVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI 61
ycf16 CHL00131
sulfate ABC transporter protein; Validated
494-531 1.47e-03

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 42.32  E-value: 1.47e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 6005701    494 DKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSG 531
Cdd:CHL00131   18 NENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG 55
7TMR-DISM_7TM pfam07695
7TM diverse intracellular signalling; This entry represents the transmembrane region of the ...
267-421 1.95e-03

7TM diverse intracellular signalling; This entry represents the transmembrane region of the 7TM-DISM (7TM Receptors with Diverse Intracellular Signalling Modules).


Pssm-ID: 429600 [Multi-domain]  Cd Length: 207  Bit Score: 41.49  E-value: 1.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     267 LSWGLLYaGFIFIMA---LFLALVIRSTQFIILSGFMVVFSLFLLYGLSLVALAFLMSILVKKSFLTGLVVFLLTVFWGC 343
Cdd:pfam07695    3 LLLGLFY-GILLALAlynLFLFFSLRDRSYLYYVLYLLSFLLYQLSLNGLGFQYLWPNAPPWLNNKLLYLSLLLLLPFFA 81
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6005701     344 LGFTSLYRHLPASLEWILSLLSPFAFMLGMAQLLhldydlnsnAFPHPSDGSNLIVATNFMLAFDTCLYLALAIYFEK 421
Cdd:pfam07695   82 LLFARSFLELKKYLPRLLRLLLGLALLLALLLLL---------LPLFPYTLSLPLAQLLALLFILFLLLLGIIAWRKG 150
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
477-633 2.96e-03

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 41.41  E-value: 2.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    477 KEAIRIRNVTKEYKgkpDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEmADLENl 556
Cdd:PRK15056    4 QAGIVVNDVTVTWR---NGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQ-ALQKN- 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    557 skLTGVCPQS-NVQFDFLTVRENLRLFAKI--KGIL--PQEVDKEI---------------------------------- 597
Cdd:PRK15056   79 --LVAYVPQSeEVDWSFPVLVEDVVMMGRYghMGWLrrAKKRDRQIvtaalarvdmvefrhrqigelsggqkkrvflara 156
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 6005701    598 -------FLLDEPTAGLDPFSRHQVWNLLKE-RKTDRVILFSTQ 633
Cdd:PRK15056  157 iaqqgqvILLDEPFTGVDVKTEARIISLLRElRDEGKTMLVSTH 200
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
1257-1311 3.41e-03

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 41.62  E-value: 3.41e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 6005701   1257 FSKRKNKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG 1311
Cdd:PRK15079   28 WQPPKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLG 82
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
469-559 3.50e-03

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 41.88  E-value: 3.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    469 QAPPEFQgkeAIRIRNVTKEYkgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLS 548
Cdd:PRK10522  315 QAFPDWQ---TLELRNVTFAY---QDNGFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVT 388
                          90
                  ....*....|.
gi 6005701    549 eMADLENLSKL 559
Cdd:PRK10522  389 -AEQPEDYRKL 398
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
1265-1311 3.75e-03

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 41.64  E-value: 3.75e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 6005701   1265 ATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKG 1311
Cdd:PRK10982   13 ALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQG 59
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
502-550 3.83e-03

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 40.69  E-value: 3.83e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 6005701    502 LVFDIYEGQITAILGHSGAGKSTLLNILSGLSvPTKGSVTIYNNKLSEM 550
Cdd:PRK03695   15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLL-PGSGSIQFAGQPLEAW 62
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
501-579 4.32e-03

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 40.90  E-value: 4.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701    501 DLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMA--DLENLSKLTGVCPQSNVQFDFLTVREN 578
Cdd:PRK11831   25 NISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSrsRLYTVRKRMSMLFQSGALFTDMNVFDN 104

                  .
gi 6005701    579 L 579
Cdd:PRK11831  105 V 105
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
499-532 4.73e-03

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 39.44  E-value: 4.73e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 6005701   499 LKDLVFDIYEGQITAILGHSGAGKSTLLNILSGL 532
Cdd:cd03223   17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGL 50
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
465-584 4.75e-03

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 41.85  E-value: 4.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6005701     465 DSFEQAPPEFQGKEAIRIRNVTKEY-KGKPdkiEALKDLVFDIYEGQITAILGHSGAGKSTLLNILsglsvptkgsvtiy 543
Cdd:TIGR00957  622 DSIERRTIKPGEGNSITVHNATFTWaRDLP---PTLNGITFSIPEGALVAVVGQVGCGKSSLLSAL-------------- 684
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 6005701     544 nnkLSEMADLENLSKLTG----VCPQSNVQFDflTVRENLrLFAK 584
Cdd:TIGR00957  685 ---LAEMDKVEGHVHMKGsvayVPQQAWIQND--SLRENI-LFGK 723
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
499-540 6.81e-03

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 41.43  E-value: 6.81e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 6005701     499 LKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGSV 540
Cdd:TIGR01271  442 LKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKI 483
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
482-532 7.91e-03

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 40.69  E-value: 7.91e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 6005701     482 IRNVTKEYkgkPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGL 532
Cdd:TIGR03719    7 MNRVSKVV---PPKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGV 54
ABC_MutS2 cd03280
ATP-binding cassette domain of MutS2; MutS2 homologs in bacteria and eukaryotes. The MutS ...
1377-1437 7.92e-03

ATP-binding cassette domain of MutS2; MutS2 homologs in bacteria and eukaryotes. The MutS protein initiates DNA mismatch repair by recognizing mispaired and unpaired bases embedded in duplex DNA and activating endo- and exonucleases to remove the mismatch. Members of the MutS family also possess a conserved ATPase activity that belongs to the ATP binding cassette (ABC) superfamily. MutS homologs (MSH) have been identified in most prokaryotic and all eukaryotic organisms examined. Prokaryotes have two homologs (MutS1 and MutS2), whereas seven MSH proteins (MSH1 to MSH7) have been identified in eukaryotes. The homodimer MutS1 and heterodimers MSH2-MSH3 and MSH2-MSH6 are primarily involved in mitotic mismatch repair, whereas MSH4-MSH5 is involved in resolution of Holliday junctions during meiosis. All members of the MutS family contain the highly conserved Walker A/B ATPase domain, and many share a common mechanism of action. MutS1, MSH2-MSH3, MSH2-MSH6, and MSH4-MSH5 dimerize to form sliding clamps, and recognition of specific DNA structures or lesions results in ADP/ATP exchange.


Pssm-ID: 213247 [Multi-domain]  Cd Length: 200  Bit Score: 39.54  E-value: 7.92e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6005701  1377 TLSEGIKRkLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHY 1437
Cdd:cd03280   91 TFSSHMKN-IARILQHADPDSLVLLDELGSGTDPVEGAALAIAILEELLERGALVIATTHY 150
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
480-541 8.03e-03

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 40.82  E-value: 8.03e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6005701   480 IRIRNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKS-TLLNIL----SGLSVPTkGSVT 541
Cdd:COG4172    7 LSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSvTALSILrllpDPAAHPS-GSIL 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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