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Concise Results
Standard Results
Full Results
coatomer subunit beta [Saccharomyces cerevisiae S288C]
Protein Classification
COG5096 family protein ( domain architecture ID 11473802 )
COG5096 family protein
List of domain hits
Name
Accession
Description
Interval
E-value
COG5096
COG5096 Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular ...
1-941
0e+00
Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 227427 [Multi-domain]
Cd Length: 757
Bit Score: 704.95
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 1 M TSL S SQPAYTLVFDPSP S METY SS TD fqka LE KGS D EQ KID T MK S I LVT M LE G NP M PE L LMHI I RF V M p SKNK ELK K LL 80
Cdd:COG5096 1 M RIM S AFKDSIRKARNAD S VAAL SS GR ---- LE SSN D YK KID A MK K I IAQ M SL G ED M SS L FPDV I KN V A - TRDV ELK R LL 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 81 Y F Y W E IVP KL AE dgklr HEMI L VC N A IQ H DLQ H PNE Y IRG NT LR F L TK LR EA ELL EQMVPSVLAC L EYR HAYVRK Y A I LA 160
Cdd:COG5096 76 Y L Y L E RYA KL KP ----- ELAL L AV N T IQ K DLQ D PNE E IRG FA LR T L SL LR VK ELL GNIIDPIKKL L TDP HAYVRK T A A LA 150
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 161 V FSIFKVSEH L LPDA - KEI I NSFI VA ET DPI CKR NA FIG LAE L D R E N A LH Y LENN I AD I EN LD P L LQA V F vqfirqdanr 239
Cdd:COG5096 151 V AKLYRLDKD L YHEL g LID I LKEL VA DS DPI VIA NA LAS LAE I D P E L A HG Y SLEV I LR I PQ LD L L SLS V S ---------- 220
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 240 T PA L KAQYI E L L M E LLS TT TSDEVI FE TA L ALTVLSA N PN VL VP AV NKLID L A V KVSD NN IK LI VLDRIQDIN A NN vgal 319
Cdd:COG5096 221 T EW L LLIIL E V L T E RVP TT PDSAED FE ER L SPPLQHN N AE VL LI AV KVILR L L V FLPS NN LF LI SSPPLVTLL A KP ---- 296
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 320 E E L TLDI LR VLNAE DL D V R SK A LD ISMD L ATSRNAE D VVQL L K K EL Q T T VNNP DQ DKA mqyr Q L L IKT I RTV A V N F ve MA 399
Cdd:COG5096 297 E S L IQYV LR RNIQI DL E V C SK L LD KVKK L FLIEYND D IYIK L E K LD Q L T RLAD DQ NLS ---- Q I L LEL I YYI A E N H -- ID 370
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 400 A SV VS LLLDFI GDL N S V A A S GIIAF I K E VI E KYP qlranilenmvqtldkvrsakayrg AL WI M G E Y AEG E SE I QH C WKH 479
Cdd:COG5096 371 A EM VS EAIKAL GDL A S K A E S SVNDC I S E LL E LLE ------------------------- GV WI R G S Y IVQ E VR I VD C ISV 425
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 480 IR N SV GEVP IL QS E ikkltqnqehteenevdatakpt G P V IL PD G T YA T E SAFD vktsqksvtdee RD SR P P IRRF V L sg 559
Cdd:COG5096 426 IR I SV LVLR IL PN E ----------------------- Y P K IL LR G L YA L E ETLE ------------ LQ SR E P RAKS V T -- 468
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 560 D F Y TA A I L ANTIIKLVLKF E nvsknktvinalka EA LL ILVSIVR V GQSSL V EKK I DED S LERVMT SI SILLDEVN peek 639
Cdd:COG5096 469 D K Y LG A W L LGEFSDIIPRL E -------------- PE LL RIAISNF V DETLE V QYT I LMS S VKLIAN SI RKAKQCNS ---- 530
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 640 keevkllevafldttkssfkrqieiakknkhkralkdscknie PI D TPISF R Q F AG V D stnvqkdsi EE DL QLAMK gda I 719
Cdd:COG5096 531 ------------------------------------------- EL D QDVLR R C F DY V L --------- VP DL RDRAR --- M 555
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 720 HAT ssssiskl KKIV PL CG FSDP VYA EA CIT N N QF DVV L DV LL V NQT K E T L K NL HVQ F a TLG D L KI I DTPQKT N VIPHGF 799
Cdd:COG5096 556 YSR -------- LLST PL PE FSDP ILC EA KKS N S QF EII L SA LL T NQT P E L L E NL RLD F - TLG T L ST I PLKPIF N LRKGAV 626
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 800 HKFT VTVK VSS A DT G V I F GNI IYD GA HG ED A R YVI LND VHVD I MDYIK P A T A D DEH FR TM W NAF E W ENKI SVK S - QLPT L 878
Cdd:COG5096 627 VLQQ VTVK KPN A EL G F I T GNI NPS GA AN ED L R DIN LND SINS I SGFVN P R T V D EDY FR EL W KMD E F ENKI DES S n NPKK L 706
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 398366227 879 HA Y LR E LVKGT NM G ILTPS ES L geddc R F L S CN L YA K ssfg E DAL AN LC I E kds K TND V I G YV 941
Cdd:COG5096 707 DD Y SE E KSRED NM E ILTPS DD L ----- E F S S SS L GS K ---- S DAL MS LC L E --- K PEP V L G LS 757
Name
Accession
Description
Interval
E-value
COG5096
COG5096 Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular ...
1-941
0e+00
Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 227427 [Multi-domain]
Cd Length: 757
Bit Score: 704.95
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 1 M TSL S SQPAYTLVFDPSP S METY SS TD fqka LE KGS D EQ KID T MK S I LVT M LE G NP M PE L LMHI I RF V M p SKNK ELK K LL 80
Cdd:COG5096 1 M RIM S AFKDSIRKARNAD S VAAL SS GR ---- LE SSN D YK KID A MK K I IAQ M SL G ED M SS L FPDV I KN V A - TRDV ELK R LL 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 81 Y F Y W E IVP KL AE dgklr HEMI L VC N A IQ H DLQ H PNE Y IRG NT LR F L TK LR EA ELL EQMVPSVLAC L EYR HAYVRK Y A I LA 160
Cdd:COG5096 76 Y L Y L E RYA KL KP ----- ELAL L AV N T IQ K DLQ D PNE E IRG FA LR T L SL LR VK ELL GNIIDPIKKL L TDP HAYVRK T A A LA 150
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 161 V FSIFKVSEH L LPDA - KEI I NSFI VA ET DPI CKR NA FIG LAE L D R E N A LH Y LENN I AD I EN LD P L LQA V F vqfirqdanr 239
Cdd:COG5096 151 V AKLYRLDKD L YHEL g LID I LKEL VA DS DPI VIA NA LAS LAE I D P E L A HG Y SLEV I LR I PQ LD L L SLS V S ---------- 220
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 240 T PA L KAQYI E L L M E LLS TT TSDEVI FE TA L ALTVLSA N PN VL VP AV NKLID L A V KVSD NN IK LI VLDRIQDIN A NN vgal 319
Cdd:COG5096 221 T EW L LLIIL E V L T E RVP TT PDSAED FE ER L SPPLQHN N AE VL LI AV KVILR L L V FLPS NN LF LI SSPPLVTLL A KP ---- 296
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 320 E E L TLDI LR VLNAE DL D V R SK A LD ISMD L ATSRNAE D VVQL L K K EL Q T T VNNP DQ DKA mqyr Q L L IKT I RTV A V N F ve MA 399
Cdd:COG5096 297 E S L IQYV LR RNIQI DL E V C SK L LD KVKK L FLIEYND D IYIK L E K LD Q L T RLAD DQ NLS ---- Q I L LEL I YYI A E N H -- ID 370
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 400 A SV VS LLLDFI GDL N S V A A S GIIAF I K E VI E KYP qlranilenmvqtldkvrsakayrg AL WI M G E Y AEG E SE I QH C WKH 479
Cdd:COG5096 371 A EM VS EAIKAL GDL A S K A E S SVNDC I S E LL E LLE ------------------------- GV WI R G S Y IVQ E VR I VD C ISV 425
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 480 IR N SV GEVP IL QS E ikkltqnqehteenevdatakpt G P V IL PD G T YA T E SAFD vktsqksvtdee RD SR P P IRRF V L sg 559
Cdd:COG5096 426 IR I SV LVLR IL PN E ----------------------- Y P K IL LR G L YA L E ETLE ------------ LQ SR E P RAKS V T -- 468
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 560 D F Y TA A I L ANTIIKLVLKF E nvsknktvinalka EA LL ILVSIVR V GQSSL V EKK I DED S LERVMT SI SILLDEVN peek 639
Cdd:COG5096 469 D K Y LG A W L LGEFSDIIPRL E -------------- PE LL RIAISNF V DETLE V QYT I LMS S VKLIAN SI RKAKQCNS ---- 530
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 640 keevkllevafldttkssfkrqieiakknkhkralkdscknie PI D TPISF R Q F AG V D stnvqkdsi EE DL QLAMK gda I 719
Cdd:COG5096 531 ------------------------------------------- EL D QDVLR R C F DY V L --------- VP DL RDRAR --- M 555
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 720 HAT ssssiskl KKIV PL CG FSDP VYA EA CIT N N QF DVV L DV LL V NQT K E T L K NL HVQ F a TLG D L KI I DTPQKT N VIPHGF 799
Cdd:COG5096 556 YSR -------- LLST PL PE FSDP ILC EA KKS N S QF EII L SA LL T NQT P E L L E NL RLD F - TLG T L ST I PLKPIF N LRKGAV 626
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 800 HKFT VTVK VSS A DT G V I F GNI IYD GA HG ED A R YVI LND VHVD I MDYIK P A T A D DEH FR TM W NAF E W ENKI SVK S - QLPT L 878
Cdd:COG5096 627 VLQQ VTVK KPN A EL G F I T GNI NPS GA AN ED L R DIN LND SINS I SGFVN P R T V D EDY FR EL W KMD E F ENKI DES S n NPKK L 706
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 398366227 879 HA Y LR E LVKGT NM G ILTPS ES L geddc R F L S CN L YA K ssfg E DAL AN LC I E kds K TND V I G YV 941
Cdd:COG5096 707 DD Y SE E KSRED NM E ILTPS DD L ----- E F S S SS L GS K ---- S DAL MS LC L E --- K PEP V L G LS 757
Adaptin_N
pfam01602 Adaptin N terminal region; This family consists of the N terminal region of various alpha, ...
20-560
1.55e-138
Adaptin N terminal region; This family consists of the N terminal region of various alpha, beta and gamma subunits of the AP-1, AP-2 and AP-3 adaptor protein complexes. The adaptor protein (AP) complexes are involved in the formation of clathrin-coated pits and vesicles. The N-terminal region of the various adaptor proteins (APs) is constant by comparison to the C-terminal which is variable within members of the AP-2 family; and it has been proposed that this constant region interacts with another uniform component of the coated vesicles.
Pssm-ID: 396262 [Multi-domain]
Cd Length: 523
Bit Score: 425.11
E-value: 1.55e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 20 M E TYSSTDFQKA L EKG -- SDEQ K IDTM K SI L VTMLE G NPMPE L LMHIIRF V M p SK NKE LK K L L Y F Y WEIVPKLAE D gklr 97
Cdd:pfam01602 1 E E KRIQQELARI L NSF rd DPRK K KNAV K KL L YLIML G EDISF L FFEVVKL V A - SK DFT LK R L G Y L Y LMLLAEESP D ---- 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 98 h EM ILV C N A IQ H DLQ H PN EY IRG NT LR F L TKL R EA EL LEQMV P SVLAC L EY R HA YVRK Y A I LA VFSIFKV S EH L LP D AKE 177
Cdd:pfam01602 76 - LA ILV T N S IQ K DLQ S PN QL IRG LA LR T L SCI R VP EL ARDLA P DIKKL L VD R SP YVRK K A A LA ILKLYRK S PD L VR D FVP 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 178 IINS f IVAET DP ICKRN A FIG L A E LDREN ----- A L HY L ENNIADIEN - L D P L LQ AVFVQFIRQD A NRT P A L KAQYI E L L 251
Cdd:pfam01602 155 ELKE - LLSDK DP GVQSA A VAL L Y E ICKND rlylk L L PL L FRRLCNLLG v L N P W LQ VKILRLLTRL A PLD P L L PKELL E D L 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 252 ME LL S t TTSDE V IF ETA LALTV L SAN P NVL V P AVN K L ID L AV k VS D N N IKLIV L DRIQD I NANNVG A LEE L T L D I LRVLN 331
Cdd:pfam01602 234 LN LL Q - NSNNA V LY ETA NTIVH L APA P ELI V L AVN A L GR L LS - SP D E N LRYVA L RNLNK I VMKEPK A VQH L D L I I FCLKT 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 332 AE D LDV R SK ALD ISMD L ATSR N AEDV V QL L K K EL qtt VNNP D Q D kamq YRQL L IKT I RTV A VN F VEM A ASVVSL LLD FIG 411
Cdd:pfam01602 312 DD D ISI R LR ALD LLYA L VNES N VKEI V KE L L K YV --- HEIA D P D ---- FKIE L VRA I GRL A EK F PTD A EWYLDV LLD LLS 384
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 412 DLN S VAASG I IAF I KEV I EKY P Q LR AN ILE NMVQT L DKVR S AK A YRG ALWI M GEY A E GESEI q HCWKHIRN S VG EV PI L Q 491
Cdd:pfam01602 385 LAG S YVVDE I VEV I RDI I QNV P E LR EY ILE HLCEL L EDIE S PE A LAA ALWI L GEY G E LIPNG - SSPPDLLR S IL EV FV L E 463
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 398366227 492 S EIKKLTQNQEHTEENEVDATAKPTGPV I LPDG T Y AT ESAF D VKTSQKS V tdeerdsrp PIR R FVLSG D 560
Cdd:pfam01602 464 S AKVRAAALTALAKLGLTSPEETTQNLI I QLLL T L AT QDSL D LEVRDRA V --------- EYL R LLSLA D 523
PTZ00429
PTZ00429 beta-adaptin; Provisional
26-468
6.89e-11
beta-adaptin; Provisional
Pssm-ID: 240415 [Multi-domain]
Cd Length: 746
Bit Score: 66.11
E-value: 6.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 26 TDF Q KA L EKGSDEQ K IDTM K S I LVT M LE G NPMPE L LMHIIR f VM PS KNK ELKKL L Y F Y WEIVPK L AEDGK L rhemi L VC N 105
Cdd:PTZ00429 35 AEL Q ND L NGTDSYR K KAAV K R I IAN M TM G RDVSY L FVDVVK - LA PS TDL ELKKL V Y L Y VLSTAR L QPEKA L ----- L AV N 108
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 106 AIQH D LQHPNEYI R GNTL R FLTKL R EAEL LE QMVPSVLACLEYRHA YVRK Y A ILAVFSI F KVSEH L LPD --- A K EIIN sf 182
Cdd:PTZ00429 109 TFLQ D TTNSSPVV R ALAV R TMMCI R VSSV LE YTLEPLRRAVADPDP YVRK T A AMGLGKL F HDDMQ L FYQ qdf K K DLVE -- 186
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 183 IVAETD P ICKR NA FIGLA E LDRENALHYLEN N iadi E NLDP L LQAV fvqfirqda NRTPALKAQ YI ell M ELL STTT - SD 261
Cdd:PTZ00429 187 LLNDNN P VVAS NA AAIVC E VNDYGSEKIESS N ---- E WVNR L VYHL --------- PECNEWGQL YI --- L ELL AAQR p SD 250
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 262 EVIF ET A L ALTVLS --- A NP N V LVP A VNKLID LA VKV S DN --------- N IK L IV L D R ---- I Q D I NAN N VG AL EEL --- 322
Cdd:PTZ00429 251 KESA ET L L TRVLPR msh Q NP A V VMG A IKVVAN LA SRC S QE lierctvrv N TA L LT L S R rdae T Q Y I VCK N IH AL LVI fpn 330
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 323 ---- T LD ILR V LNAEDLD V RSKA L DISMD L A T SRN A EDVV qllk KEL QTTVNNP D qdka M QYRQLLIKT I RTV A VNFVEM 398
Cdd:PTZ00429 331 llrt N LD SFY V RYSDPPF V KLEK L RLLLK L V T PSV A PEIL ---- KEL AEYASGV D ---- M VFVVEVVRA I ASL A IKVDSV 402
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 398366227 399 A ASVVS LLL DFIGDLNSVAAS g IIAFI K EVIE KYP Q L R an I L ENM V QT -- L D K V RSAK A YRGA LW IM GEY AE 468
Cdd:PTZ00429 403 A PDCAN LLL QIVDRRPELLPQ - VVTAA K DIVR KYP E L L -- M L DTL V TD yg A D E V VEEE A KVSL LW ML GEY CD 471
Name
Accession
Description
Interval
E-value
COG5096
COG5096 Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular ...
1-941
0e+00
Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 227427 [Multi-domain]
Cd Length: 757
Bit Score: 704.95
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 1 M TSL S SQPAYTLVFDPSP S METY SS TD fqka LE KGS D EQ KID T MK S I LVT M LE G NP M PE L LMHI I RF V M p SKNK ELK K LL 80
Cdd:COG5096 1 M RIM S AFKDSIRKARNAD S VAAL SS GR ---- LE SSN D YK KID A MK K I IAQ M SL G ED M SS L FPDV I KN V A - TRDV ELK R LL 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 81 Y F Y W E IVP KL AE dgklr HEMI L VC N A IQ H DLQ H PNE Y IRG NT LR F L TK LR EA ELL EQMVPSVLAC L EYR HAYVRK Y A I LA 160
Cdd:COG5096 76 Y L Y L E RYA KL KP ----- ELAL L AV N T IQ K DLQ D PNE E IRG FA LR T L SL LR VK ELL GNIIDPIKKL L TDP HAYVRK T A A LA 150
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 161 V FSIFKVSEH L LPDA - KEI I NSFI VA ET DPI CKR NA FIG LAE L D R E N A LH Y LENN I AD I EN LD P L LQA V F vqfirqdanr 239
Cdd:COG5096 151 V AKLYRLDKD L YHEL g LID I LKEL VA DS DPI VIA NA LAS LAE I D P E L A HG Y SLEV I LR I PQ LD L L SLS V S ---------- 220
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 240 T PA L KAQYI E L L M E LLS TT TSDEVI FE TA L ALTVLSA N PN VL VP AV NKLID L A V KVSD NN IK LI VLDRIQDIN A NN vgal 319
Cdd:COG5096 221 T EW L LLIIL E V L T E RVP TT PDSAED FE ER L SPPLQHN N AE VL LI AV KVILR L L V FLPS NN LF LI SSPPLVTLL A KP ---- 296
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 320 E E L TLDI LR VLNAE DL D V R SK A LD ISMD L ATSRNAE D VVQL L K K EL Q T T VNNP DQ DKA mqyr Q L L IKT I RTV A V N F ve MA 399
Cdd:COG5096 297 E S L IQYV LR RNIQI DL E V C SK L LD KVKK L FLIEYND D IYIK L E K LD Q L T RLAD DQ NLS ---- Q I L LEL I YYI A E N H -- ID 370
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 400 A SV VS LLLDFI GDL N S V A A S GIIAF I K E VI E KYP qlranilenmvqtldkvrsakayrg AL WI M G E Y AEG E SE I QH C WKH 479
Cdd:COG5096 371 A EM VS EAIKAL GDL A S K A E S SVNDC I S E LL E LLE ------------------------- GV WI R G S Y IVQ E VR I VD C ISV 425
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 480 IR N SV GEVP IL QS E ikkltqnqehteenevdatakpt G P V IL PD G T YA T E SAFD vktsqksvtdee RD SR P P IRRF V L sg 559
Cdd:COG5096 426 IR I SV LVLR IL PN E ----------------------- Y P K IL LR G L YA L E ETLE ------------ LQ SR E P RAKS V T -- 468
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 560 D F Y TA A I L ANTIIKLVLKF E nvsknktvinalka EA LL ILVSIVR V GQSSL V EKK I DED S LERVMT SI SILLDEVN peek 639
Cdd:COG5096 469 D K Y LG A W L LGEFSDIIPRL E -------------- PE LL RIAISNF V DETLE V QYT I LMS S VKLIAN SI RKAKQCNS ---- 530
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 640 keevkllevafldttkssfkrqieiakknkhkralkdscknie PI D TPISF R Q F AG V D stnvqkdsi EE DL QLAMK gda I 719
Cdd:COG5096 531 ------------------------------------------- EL D QDVLR R C F DY V L --------- VP DL RDRAR --- M 555
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 720 HAT ssssiskl KKIV PL CG FSDP VYA EA CIT N N QF DVV L DV LL V NQT K E T L K NL HVQ F a TLG D L KI I DTPQKT N VIPHGF 799
Cdd:COG5096 556 YSR -------- LLST PL PE FSDP ILC EA KKS N S QF EII L SA LL T NQT P E L L E NL RLD F - TLG T L ST I PLKPIF N LRKGAV 626
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 800 HKFT VTVK VSS A DT G V I F GNI IYD GA HG ED A R YVI LND VHVD I MDYIK P A T A D DEH FR TM W NAF E W ENKI SVK S - QLPT L 878
Cdd:COG5096 627 VLQQ VTVK KPN A EL G F I T GNI NPS GA AN ED L R DIN LND SINS I SGFVN P R T V D EDY FR EL W KMD E F ENKI DES S n NPKK L 706
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 398366227 879 HA Y LR E LVKGT NM G ILTPS ES L geddc R F L S CN L YA K ssfg E DAL AN LC I E kds K TND V I G YV 941
Cdd:COG5096 707 DD Y SE E KSRED NM E ILTPS DD L ----- E F S S SS L GS K ---- S DAL MS LC L E --- K PEP V L G LS 757
Adaptin_N
pfam01602 Adaptin N terminal region; This family consists of the N terminal region of various alpha, ...
20-560
1.55e-138
Adaptin N terminal region; This family consists of the N terminal region of various alpha, beta and gamma subunits of the AP-1, AP-2 and AP-3 adaptor protein complexes. The adaptor protein (AP) complexes are involved in the formation of clathrin-coated pits and vesicles. The N-terminal region of the various adaptor proteins (APs) is constant by comparison to the C-terminal which is variable within members of the AP-2 family; and it has been proposed that this constant region interacts with another uniform component of the coated vesicles.
Pssm-ID: 396262 [Multi-domain]
Cd Length: 523
Bit Score: 425.11
E-value: 1.55e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 20 M E TYSSTDFQKA L EKG -- SDEQ K IDTM K SI L VTMLE G NPMPE L LMHIIRF V M p SK NKE LK K L L Y F Y WEIVPKLAE D gklr 97
Cdd:pfam01602 1 E E KRIQQELARI L NSF rd DPRK K KNAV K KL L YLIML G EDISF L FFEVVKL V A - SK DFT LK R L G Y L Y LMLLAEESP D ---- 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 98 h EM ILV C N A IQ H DLQ H PN EY IRG NT LR F L TKL R EA EL LEQMV P SVLAC L EY R HA YVRK Y A I LA VFSIFKV S EH L LP D AKE 177
Cdd:pfam01602 76 - LA ILV T N S IQ K DLQ S PN QL IRG LA LR T L SCI R VP EL ARDLA P DIKKL L VD R SP YVRK K A A LA ILKLYRK S PD L VR D FVP 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 178 IINS f IVAET DP ICKRN A FIG L A E LDREN ----- A L HY L ENNIADIEN - L D P L LQ AVFVQFIRQD A NRT P A L KAQYI E L L 251
Cdd:pfam01602 155 ELKE - LLSDK DP GVQSA A VAL L Y E ICKND rlylk L L PL L FRRLCNLLG v L N P W LQ VKILRLLTRL A PLD P L L PKELL E D L 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 252 ME LL S t TTSDE V IF ETA LALTV L SAN P NVL V P AVN K L ID L AV k VS D N N IKLIV L DRIQD I NANNVG A LEE L T L D I LRVLN 331
Cdd:pfam01602 234 LN LL Q - NSNNA V LY ETA NTIVH L APA P ELI V L AVN A L GR L LS - SP D E N LRYVA L RNLNK I VMKEPK A VQH L D L I I FCLKT 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 332 AE D LDV R SK ALD ISMD L ATSR N AEDV V QL L K K EL qtt VNNP D Q D kamq YRQL L IKT I RTV A VN F VEM A ASVVSL LLD FIG 411
Cdd:pfam01602 312 DD D ISI R LR ALD LLYA L VNES N VKEI V KE L L K YV --- HEIA D P D ---- FKIE L VRA I GRL A EK F PTD A EWYLDV LLD LLS 384
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 412 DLN S VAASG I IAF I KEV I EKY P Q LR AN ILE NMVQT L DKVR S AK A YRG ALWI M GEY A E GESEI q HCWKHIRN S VG EV PI L Q 491
Cdd:pfam01602 385 LAG S YVVDE I VEV I RDI I QNV P E LR EY ILE HLCEL L EDIE S PE A LAA ALWI L GEY G E LIPNG - SSPPDLLR S IL EV FV L E 463
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 398366227 492 S EIKKLTQNQEHTEENEVDATAKPTGPV I LPDG T Y AT ESAF D VKTSQKS V tdeerdsrp PIR R FVLSG D 560
Cdd:pfam01602 464 S AKVRAAALTALAKLGLTSPEETTQNLI I QLLL T L AT QDSL D LEVRDRA V --------- EYL R LLSLA D 523
Coatomer_b_Cpla
pfam14806 Coatomer beta subunit appendage platform; This family is found at the C-terminus of the ...
829-958
1.36e-68
Coatomer beta subunit appendage platform; This family is found at the C-terminus of the coatamer beta subunit proteins (Beta-coat proteins). It is a platform domain on the appendage that carries a highly conserved tryptophan.
Pssm-ID: 434227
Cd Length: 128
Bit Score: 224.37
E-value: 1.36e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 829 D ARY VILND V H V DIMDYIKPAT A DDE H FR T MW NA FEWENKI S V KSQLPT L HA YL RE L V K G TNM GI LTP S E S L g EDD C R FL 908
Cdd:pfam14806 1 D RNC VILND I H I DIMDYIKPAT C DDE E FR E MW AE FEWENKI T V NTNITD L RE YL DH L M K K TNM NC LTP E E A L - SGE C G FL 79
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 398366227 909 S C NLYA K S S FGEDALANL C IEKD S k TNDVI G Y VRIRSK G QG L ALSLGD RV 958
Cdd:pfam14806 80 S A NLYA R S I FGEDALANL S IEKD G - DGKIS G H VRIRSK T QG I ALSLGD KI 128
Coatamer_beta_C
pfam07718 Coatomer beta C-terminal region; This family is found at the C-terminus of the coatamer beta ...
684-824
1.26e-65
Coatomer beta C-terminal region; This family is found at the C-terminus of the coatamer beta subunit proteins (Beta-coat proteins). This C-terminal domain probably adapts the function of the N-terminal pfam01602 domain.
Pssm-ID: 462245 [Multi-domain]
Cd Length: 138
Bit Score: 216.63
E-value: 1.26e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 684 I D T PISFRQ FA G VDSTNVQKDSI E E DL QL A MK GD AIHATS SS SIS K L kki V P L C GFSDPVYAEA CI T NN QFD V VLDVLLV 763
Cdd:pfam07718 1 P D D PISFRQ LK G KKGESGEELQF E D DL SQ A TG GD IAEDDF SS KLN K I --- V Q L T GFSDPVYAEA YV T VH QFD I VLDVLLV 77
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 398366227 764 NQT K ETL K NL H V QF ATLGDLK IIDT PQ KTNVI PHGFH KFTV TVKVSS AD TGVIFGNI I YDG 824
Cdd:pfam07718 78 NQT S ETL Q NL T V EL ATLGDLK LVER PQ PVTLA PHGFH NIKA TVKVSS TE TGVIFGNI V YDG 138
PTZ00429
PTZ00429 beta-adaptin; Provisional
26-468
6.89e-11
beta-adaptin; Provisional
Pssm-ID: 240415 [Multi-domain]
Cd Length: 746
Bit Score: 66.11
E-value: 6.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 26 TDF Q KA L EKGSDEQ K IDTM K S I LVT M LE G NPMPE L LMHIIR f VM PS KNK ELKKL L Y F Y WEIVPK L AEDGK L rhemi L VC N 105
Cdd:PTZ00429 35 AEL Q ND L NGTDSYR K KAAV K R I IAN M TM G RDVSY L FVDVVK - LA PS TDL ELKKL V Y L Y VLSTAR L QPEKA L ----- L AV N 108
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 106 AIQH D LQHPNEYI R GNTL R FLTKL R EAEL LE QMVPSVLACLEYRHA YVRK Y A ILAVFSI F KVSEH L LPD --- A K EIIN sf 182
Cdd:PTZ00429 109 TFLQ D TTNSSPVV R ALAV R TMMCI R VSSV LE YTLEPLRRAVADPDP YVRK T A AMGLGKL F HDDMQ L FYQ qdf K K DLVE -- 186
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 183 IVAETD P ICKR NA FIGLA E LDRENALHYLEN N iadi E NLDP L LQAV fvqfirqda NRTPALKAQ YI ell M ELL STTT - SD 261
Cdd:PTZ00429 187 LLNDNN P VVAS NA AAIVC E VNDYGSEKIESS N ---- E WVNR L VYHL --------- PECNEWGQL YI --- L ELL AAQR p SD 250
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 262 EVIF ET A L ALTVLS --- A NP N V LVP A VNKLID LA VKV S DN --------- N IK L IV L D R ---- I Q D I NAN N VG AL EEL --- 322
Cdd:PTZ00429 251 KESA ET L L TRVLPR msh Q NP A V VMG A IKVVAN LA SRC S QE lierctvrv N TA L LT L S R rdae T Q Y I VCK N IH AL LVI fpn 330
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 323 ---- T LD ILR V LNAEDLD V RSKA L DISMD L A T SRN A EDVV qllk KEL QTTVNNP D qdka M QYRQLLIKT I RTV A VNFVEM 398
Cdd:PTZ00429 331 llrt N LD SFY V RYSDPPF V KLEK L RLLLK L V T PSV A PEIL ---- KEL AEYASGV D ---- M VFVVEVVRA I ASL A IKVDSV 402
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 398366227 399 A ASVVS LLL DFIGDLNSVAAS g IIAFI K EVIE KYP Q L R an I L ENM V QT -- L D K V RSAK A YRGA LW IM GEY AE 468
Cdd:PTZ00429 403 A PDCAN LLL QIVDRRPELLPQ - VVTAA K DIVR KYP E L L -- M L DTL V TD yg A D E V VEEE A KVSL LW ML GEY CD 471
SEC21
COG5240 Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion];
71-484
2.99e-04
Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion];
Pssm-ID: 227565 [Multi-domain]
Cd Length: 898
Bit Score: 44.99
E-value: 2.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 71 S K NKE L KKLL Y FYWEIVP KL A ED G klrhem ILVCNA I QH DL QHPNEY - IRGNTL R F L TKLREA E lleq M V PSVLAC L EY - 148
Cdd:COG5240 76 H K DLY L RQCV Y SAIKELS KL T ED V ------ LMGTSS I MK DL NGGVPD d VKPMAI R S L FSVIDG E ---- T V YDFERY L NQ a 145
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 149 --- RHAYV R KY A IL avfsifk V SE HLLP DAKEIINSFIVAETD ---------------------- PI CKRN A FIG L AELD 203
Cdd:COG5240 146 fvs TSMAR R SA A LV ------- V AY HLLP NNFNQTKRWLNETQE avldlkqfpnqhgnegyepngn PI SQYH A LGL L YQSK 218
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 204 R ENALHY L ENNIADIE N LDPLL Q AVF V QFI R QDAN --- RTPALKA Q YIEL L MEL LS TT t SDE V IF E T A L A LTV LS --- AN 277
Cdd:COG5240 219 R TDKMAQ L KLVEHFRG N ASMKN Q LAG V LLV R ATVE llk ENSQALL Q LRPF L NSW LS DK - FEM V FL E A A R A VCA LS een VG 297
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 278 PNVLVPA V NK L IDL -- AVK V SDNNIKLIV L DRIQDINANN V GALE eltldilrv LNA E D L d VRSKALD IS MDLA T SR --- 352
Cdd:COG5240 298 SQFVDQT V SS L RTF lk STR V VLRFSAMRI L NQLAMKYPQK V SVCN --------- KEV E S L - ISDENRT IS TYAI T TL lkt 367
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366227 353 - NA E DVVQ L LK kelqt TVNNPDQ D KAMQYRQLL I KTI R TVAVN F VEMAA S VVSL L LDFIGDLNSVA - ASGIIAF I KEVI E 430
Cdd:COG5240 368 g TE E TIDR L VN ----- LIPSFVH D MSDGFKIIA I DAL R SLSLL F PSKKL S YLDF L GSSLLQEGGLE f KKYMVDA I SDAM E 442
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 398366227 431 KY P QLRANI LE NMVQTLDKVRSAKAYRGA L W I M G EYAEGESEIQHCWK HI R N SV 484
Cdd:COG5240 443 ND P DSKERA LE VLCTFIEDCEYHQITVRI L G I L G REGPRAKTPGKYVR HI Y N RL 496
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
