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Concise Results
Standard Results
Full Results
Apl6p [Saccharomyces cerevisiae S288C]
Protein Classification
COG5096 family protein ( domain architecture ID 11473802 )
COG5096 family protein
List of domain hits
Name
Accession
Description
Interval
E-value
COG5096
COG5096 Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular ...
6-770
0e+00
Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 227427 [Multi-domain]
Cd Length: 757
Bit Score: 658.34
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 6 H RI A SA LDTAKVIT R E A AA VA TSKL G E ssytyysqninpqqlvtl L N S R N SREVR DAMK R II SI M ASDD D sid VQLY F A D 85
Cdd:COG5096 1 M RI M SA FKDSIRKA R N A DS VA ALSS G R ------------------ L E S S N DYKKI DAMK K II AQ M SLGE D --- MSSL F P D 59
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 86 V V KN IT T N D TKV KRL IH LYL L R F A END P N L T LL SI N SL QK S L S D S N S E L R C FAL SA LS DMKMSS L API I LHTV KKL V TDP 165
Cdd:COG5096 60 V I KN VA T R D VEL KRL LY LYL E R Y A KLK P E L A LL AV N TI QK D L Q D P N E E I R G FAL RT LS LLRVKE L LGN I IDPI KKL L TDP 139
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 166 S A M VR GEV ALA II KLYR AG K ND YHE E - L L DILKEL M AD T DP K VI SC A VLAYK E CYA dhl EL L HG HFRRYCRI I K QLD -- S 242
Cdd:COG5096 140 H A Y VR KTA ALA VA KLYR LD K DL YHE L g L I DILKEL V AD S DP I VI AN A LASLA E IDP --- EL A HG YSLEVILR I P QLD ll S 216
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 243 W S Q S YLIE LLI KYCKQYLPK PT VV D k S S E GSPRSCPL P DKY N EI E YPSYE V VNDPD L DL FL Q S L N CLIY SS N P T V I L SCC 322
Cdd:COG5096 217 L S V S TEWL LLI ILEVLTERV PT TP D - S A E DFEERLSP P LQH N NA E VLLIA V KVILR L LV FL P S N N LFLI SS P P L V T L LAK 295
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 323 N a LYQLASP L QMKNTKFI E ALVRTVTMTENQGNK E MLLQAIHF L SI LDQ TLF L PYTKKFYV fpkd PIVAS I WK I QI ls TL 402
Cdd:COG5096 296 P - ESLIQYV L RRNIQIDL E VCSKLLDKVKKLFLI E YNDDIYIK L EK LDQ LTR L ADDQNLSQ ---- ILLEL I YY I AE -- NH 368
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 403 I NESN V K E IF K E L KYYVAS A HFPE N VV I MAVKS L SR cgqlstsw ESHVMKWL I DHMESHNLSA SV LDAY V N V I R M L VQKN 482
Cdd:COG5096 369 I DAEM V S E AI K A L GDLASK A ESSV N DC I SELLE L LE -------- GVWIRGSY I VQEVRIVDCI SV IRIS V L V L R I L PNEY 440
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 483 P TKH LR IIFK L ADL L TV Q TSLADNARAG ---- IV WL F GE IAS I EFKIC P DV LR RL I Q NF SN E GP E TRCQ IL VL S A KL LSY 558
Cdd:COG5096 441 P KIL LR GLYA L EET L EL Q SREPRAKSVT dkyl GA WL L GE FSD I IPRLE P EL LR IA I S NF VD E TL E VQYT IL MS S V KL IAN 520
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 559 D I DNF K qaqvtgseenn Q NPPYY D FSGS R ISQM Y NA V L ylakyddef D I RDRARM I S S L FDSGKY E IVSLL L QAP K PTAR 638
Cdd:COG5096 521 S I RKA K ----------- Q CNSEL D QDVL R RCFD Y VL V P --------- D L RDRARM Y S R L LSTPLP E FSDPI L CEA K KSNS 580
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 639 SDDF I V SA R L ETH TPE IK E FF R MLP - WN T EI T EVGETGNDI R E GA ELKDYNKY KK SFSSQS FIT N N SAR S ft SSS N AK L T 717
Cdd:COG5096 581 QFEI I L SA L L TNQ TPE LL E NL R LDF t LG T LS T IPLKPIFNL R K GA VVLQQVTV KK PNAELG FIT G N INP S -- GAA N ED L R 658
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|...
gi 398366337 718 G IN DG DS n SI S GK G N VN TF T SQNGKKYR L QSL DEF FSD I P E RKSK P R K IIKVV 770
Cdd:COG5096 659 D IN LN DS - IN S IS G F VN PR T VDEDYFRE L WKM DEF ENK I D E SSNN P K K LDDYS 710
Name
Accession
Description
Interval
E-value
COG5096
COG5096 Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular ...
6-770
0e+00
Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 227427 [Multi-domain]
Cd Length: 757
Bit Score: 658.34
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 6 H RI A SA LDTAKVIT R E A AA VA TSKL G E ssytyysqninpqqlvtl L N S R N SREVR DAMK R II SI M ASDD D sid VQLY F A D 85
Cdd:COG5096 1 M RI M SA FKDSIRKA R N A DS VA ALSS G R ------------------ L E S S N DYKKI DAMK K II AQ M SLGE D --- MSSL F P D 59
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 86 V V KN IT T N D TKV KRL IH LYL L R F A END P N L T LL SI N SL QK S L S D S N S E L R C FAL SA LS DMKMSS L API I LHTV KKL V TDP 165
Cdd:COG5096 60 V I KN VA T R D VEL KRL LY LYL E R Y A KLK P E L A LL AV N TI QK D L Q D P N E E I R G FAL RT LS LLRVKE L LGN I IDPI KKL L TDP 139
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 166 S A M VR GEV ALA II KLYR AG K ND YHE E - L L DILKEL M AD T DP K VI SC A VLAYK E CYA dhl EL L HG HFRRYCRI I K QLD -- S 242
Cdd:COG5096 140 H A Y VR KTA ALA VA KLYR LD K DL YHE L g L I DILKEL V AD S DP I VI AN A LASLA E IDP --- EL A HG YSLEVILR I P QLD ll S 216
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 243 W S Q S YLIE LLI KYCKQYLPK PT VV D k S S E GSPRSCPL P DKY N EI E YPSYE V VNDPD L DL FL Q S L N CLIY SS N P T V I L SCC 322
Cdd:COG5096 217 L S V S TEWL LLI ILEVLTERV PT TP D - S A E DFEERLSP P LQH N NA E VLLIA V KVILR L LV FL P S N N LFLI SS P P L V T L LAK 295
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 323 N a LYQLASP L QMKNTKFI E ALVRTVTMTENQGNK E MLLQAIHF L SI LDQ TLF L PYTKKFYV fpkd PIVAS I WK I QI ls TL 402
Cdd:COG5096 296 P - ESLIQYV L RRNIQIDL E VCSKLLDKVKKLFLI E YNDDIYIK L EK LDQ LTR L ADDQNLSQ ---- ILLEL I YY I AE -- NH 368
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 403 I NESN V K E IF K E L KYYVAS A HFPE N VV I MAVKS L SR cgqlstsw ESHVMKWL I DHMESHNLSA SV LDAY V N V I R M L VQKN 482
Cdd:COG5096 369 I DAEM V S E AI K A L GDLASK A ESSV N DC I SELLE L LE -------- GVWIRGSY I VQEVRIVDCI SV IRIS V L V L R I L PNEY 440
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 483 P TKH LR IIFK L ADL L TV Q TSLADNARAG ---- IV WL F GE IAS I EFKIC P DV LR RL I Q NF SN E GP E TRCQ IL VL S A KL LSY 558
Cdd:COG5096 441 P KIL LR GLYA L EET L EL Q SREPRAKSVT dkyl GA WL L GE FSD I IPRLE P EL LR IA I S NF VD E TL E VQYT IL MS S V KL IAN 520
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 559 D I DNF K qaqvtgseenn Q NPPYY D FSGS R ISQM Y NA V L ylakyddef D I RDRARM I S S L FDSGKY E IVSLL L QAP K PTAR 638
Cdd:COG5096 521 S I RKA K ----------- Q CNSEL D QDVL R RCFD Y VL V P --------- D L RDRARM Y S R L LSTPLP E FSDPI L CEA K KSNS 580
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 639 SDDF I V SA R L ETH TPE IK E FF R MLP - WN T EI T EVGETGNDI R E GA ELKDYNKY KK SFSSQS FIT N N SAR S ft SSS N AK L T 717
Cdd:COG5096 581 QFEI I L SA L L TNQ TPE LL E NL R LDF t LG T LS T IPLKPIFNL R K GA VVLQQVTV KK PNAELG FIT G N INP S -- GAA N ED L R 658
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|...
gi 398366337 718 G IN DG DS n SI S GK G N VN TF T SQNGKKYR L QSL DEF FSD I P E RKSK P R K IIKVV 770
Cdd:COG5096 659 D IN LN DS - IN S IS G F VN PR T VDEDYFRE L WKM DEF ENK I D E SSNN P K K LDDYS 710
Adaptin_N
pfam01602 Adaptin N terminal region; This family consists of the N terminal region of various alpha, ...
39-622
7.03e-136
Adaptin N terminal region; This family consists of the N terminal region of various alpha, beta and gamma subunits of the AP-1, AP-2 and AP-3 adaptor protein complexes. The adaptor protein (AP) complexes are involved in the formation of clathrin-coated pits and vesicles. The N-terminal region of the various adaptor proteins (APs) is constant by comparison to the C-terminal which is variable within members of the AP-2 family; and it has been proposed that this constant region interacts with another uniform component of the coated vesicles.
Pssm-ID: 396262 [Multi-domain]
Cd Length: 523
Bit Score: 413.17
E-value: 7.03e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 39 SQNINP Q Q L VTL LNS R -- NS R EVRD A M K RIISIMASDD D sid VQLY F AD VVK NITTN D TKV KRL IH LYL LRF AE ND P N L T 116
Cdd:pfam01602 1 EEKRIQ Q E L ARI LNS F rd DP R KKKN A V K KLLYLIMLGE D --- ISFL F FE VVK LVASK D FTL KRL GY LYL MLL AE ES P D L A 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 117 L L SI NS L QK S L SDS N SEL R CF AL SA LS DMKMSS LA PIILHTV KKL VT D P S AM VR GEV ALAI I KLYR AGK n D YHEELLDI L 196
Cdd:pfam01602 78 I L VT NS I QK D L QSP N QLI R GL AL RT LS CIRVPE LA RDLAPDI KKL LV D R S PY VR KKA ALAI L KLYR KSP - D LVRDFVPE L 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 197 KEL MA D T DP K V I S C AV LAYK E - C YA D H L -- E LL HGH FRR Y C RIIKQ L DS W S Q SYLIE LL IKYCKQYLPK P tvvdkssegs 273
Cdd:pfam01602 157 KEL LS D K DP G V Q S A AV ALLY E i C KN D R L yl K LL PLL FRR L C NLLGV L NP W L Q VKILR LL TRLAPLDPLL P ---------- 226
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 274 prscplpdkyneieypsyevvndpdl DLF L QS L NC L IYS SN PT V ILSCC N ALYQ LA SPLQ m KNTKFIE AL V R TVT m TENQ 353
Cdd:pfam01602 227 -------------------------- KEL L ED L LN L LQN SN NA V LYETA N TIVH LA PAPE - LIVLAVN AL G R LLS - SPDE 278
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 354 GNKEML L QAIHFLSILD - QTLFLPYTKK F YVFPK D P I VASIWKIQI L ST L I NESNVKEI F KEL KY YV ASAHF P E n VV I MA 432
Cdd:pfam01602 279 NLRYVA L RNLNKIVMKE p KAVQHLDLII F CLKTD D D I SIRLRALDL L YA L V NESNVKEI V KEL LK YV HEIAD P D - FK I EL 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 433 V KSLS R CGQLSTSWESHVMKW L I D HMESHN ls AS V L D AY V N VIR MLV Q KN P TKHLR I IFK L AD LL TVQT S la DN A R A GIV 512
Cdd:pfam01602 358 V RAIG R LAEKFPTDAEWYLDV L L D LLSLAG -- SY V V D EI V E VIR DII Q NV P ELREY I LEH L CE LL EDIE S -- PE A L A AAL 433
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 513 W LF GE IASIEF -- KIC PD V LR RLIQN F SN E GPET R CQI L VLS AKL lsydidnfkqa QV T GS EE NN QN ppyydfsgsris Q 590
Cdd:pfam01602 434 W IL GE YGELIP ng SSP PD L LR SILEV F VL E SAKV R AAA L TAL AKL ----------- GL T SP EE TT QN ------------ L 490
570 580 590
....*....|....*....|....*....|...
gi 398366337 591 MYNAV L Y LA KY D D - EFDI RDRA RMISS L FDSGK 622
Cdd:pfam01602 491 IIQLL L T LA TQ D S l DLEV RDRA VEYLR L LSLAD 523
PTZ00429
PTZ00429 beta-adaptin; Provisional
51-611
3.71e-23
beta-adaptin; Provisional
Pssm-ID: 240415 [Multi-domain]
Cd Length: 746
Bit Score: 105.40
E-value: 3.71e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 51 LN SRN S REVRD A M KRII SI M ASDD D sid V QLY F A DVVK NITTN D TKV K R L IH LY L L RF A END P NLT LL SI N SLQKSLSD S 130
Cdd:PTZ00429 41 LN GTD S YRKKA A V KRII AN M TMGR D --- V SYL F V DVVK LAPST D LEL K K L VY LY V L ST A RLQ P EKA LL AV N TFLQDTTN S 117
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 131 NSEL R CF A LSALSDMKM SS LAPII L HTVKKL V T DP SAM VR GEV A LAII KL YRAGKN ----- D YHEE L L dilk EL MA D TD P 205
Cdd:PTZ00429 118 SPVV R AL A VRTMMCIRV SS VLEYT L EPLRRA V A DP DPY VR KTA A MGLG KL FHDDMQ lfyqq D FKKD L V ---- EL LN D NN P 193
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 206 K V I S C A --- V LAYKECYADHL E LLHGHFR R YCRIIKQLDS W S Q S Y LI ELL ikyckqylpkptvvdkssegspr SCPL P DK 282
Cdd:PTZ00429 194 V V A S N A aai V CEVNDYGSEKI E SSNEWVN R LVYHLPECNE W G Q L Y IL ELL ----------------------- AAQR P SD 250
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 283 YNEI E ypsyevvndpdl D L FLQS L NCLIY s S NP T V ILSCCNALYQ LAS PLQMKNTKFIEAL V R T VTM T ENQGNK E --- ML 359
Cdd:PTZ00429 251 KESA E ------------ T L LTRV L PRMSH - Q NP A V VMGAIKVVAN LAS RCSQELIERCTVR V N T ALL T LSRRDA E tqy IV 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 360 LQA IH F L SILDQT L FLPYTKK FYV FPK DP IVASIW K IQI L ST L INE S NVK EI F KEL KY Y VASAH -- F PEN VV i M A VK SL S 437
Cdd:PTZ00429 318 CKN IH A L LVIFPN L LRTNLDS FYV RYS DP PFVKLE K LRL L LK L VTP S VAP EI L KEL AE Y ASGVD mv F VVE VV - R A IA SL A 396
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 438 rcgqlstsweshv M K wl I D hmeshnlsa SV LDAYV N VIRML V QKN P ------- T KHLR I IF K LAD LL TVQ T SLA D ----- 505
Cdd:PTZ00429 397 ------------- I K -- V D --------- SV APDCA N LLLQI V DRR P ellpqvv T AAKD I VR K YPE LL MLD T LVT D ygade 452
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 506 ---- N A RAGIV W LF GE IASI e FKICP D VLR R L I QNFSNE gp E T R C Q ILV LSA K llsyd IDN F KQAQVT gseennqnppyy 581
Cdd:PTZ00429 453 vvee E A KVSLL W ML GE YCDF - IENGK D IIQ R F I DTIMEH -- E Q R V Q LAI LSA A ----- VKM F LRDPQG ------------ 512
570 580 590
....*....|....*....|....*....|.
gi 398366337 582 dfsgsr ISQMY N A VL - YLAKYD D EF D I RDRA 611
Cdd:PTZ00429 513 ------ MEPQL N R VL e TVTTHS D DP D V RDRA 537
Name
Accession
Description
Interval
E-value
COG5096
COG5096 Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular ...
6-770
0e+00
Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 227427 [Multi-domain]
Cd Length: 757
Bit Score: 658.34
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 6 H RI A SA LDTAKVIT R E A AA VA TSKL G E ssytyysqninpqqlvtl L N S R N SREVR DAMK R II SI M ASDD D sid VQLY F A D 85
Cdd:COG5096 1 M RI M SA FKDSIRKA R N A DS VA ALSS G R ------------------ L E S S N DYKKI DAMK K II AQ M SLGE D --- MSSL F P D 59
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 86 V V KN IT T N D TKV KRL IH LYL L R F A END P N L T LL SI N SL QK S L S D S N S E L R C FAL SA LS DMKMSS L API I LHTV KKL V TDP 165
Cdd:COG5096 60 V I KN VA T R D VEL KRL LY LYL E R Y A KLK P E L A LL AV N TI QK D L Q D P N E E I R G FAL RT LS LLRVKE L LGN I IDPI KKL L TDP 139
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 166 S A M VR GEV ALA II KLYR AG K ND YHE E - L L DILKEL M AD T DP K VI SC A VLAYK E CYA dhl EL L HG HFRRYCRI I K QLD -- S 242
Cdd:COG5096 140 H A Y VR KTA ALA VA KLYR LD K DL YHE L g L I DILKEL V AD S DP I VI AN A LASLA E IDP --- EL A HG YSLEVILR I P QLD ll S 216
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 243 W S Q S YLIE LLI KYCKQYLPK PT VV D k S S E GSPRSCPL P DKY N EI E YPSYE V VNDPD L DL FL Q S L N CLIY SS N P T V I L SCC 322
Cdd:COG5096 217 L S V S TEWL LLI ILEVLTERV PT TP D - S A E DFEERLSP P LQH N NA E VLLIA V KVILR L LV FL P S N N LFLI SS P P L V T L LAK 295
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 323 N a LYQLASP L QMKNTKFI E ALVRTVTMTENQGNK E MLLQAIHF L SI LDQ TLF L PYTKKFYV fpkd PIVAS I WK I QI ls TL 402
Cdd:COG5096 296 P - ESLIQYV L RRNIQIDL E VCSKLLDKVKKLFLI E YNDDIYIK L EK LDQ LTR L ADDQNLSQ ---- ILLEL I YY I AE -- NH 368
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 403 I NESN V K E IF K E L KYYVAS A HFPE N VV I MAVKS L SR cgqlstsw ESHVMKWL I DHMESHNLSA SV LDAY V N V I R M L VQKN 482
Cdd:COG5096 369 I DAEM V S E AI K A L GDLASK A ESSV N DC I SELLE L LE -------- GVWIRGSY I VQEVRIVDCI SV IRIS V L V L R I L PNEY 440
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 483 P TKH LR IIFK L ADL L TV Q TSLADNARAG ---- IV WL F GE IAS I EFKIC P DV LR RL I Q NF SN E GP E TRCQ IL VL S A KL LSY 558
Cdd:COG5096 441 P KIL LR GLYA L EET L EL Q SREPRAKSVT dkyl GA WL L GE FSD I IPRLE P EL LR IA I S NF VD E TL E VQYT IL MS S V KL IAN 520
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 559 D I DNF K qaqvtgseenn Q NPPYY D FSGS R ISQM Y NA V L ylakyddef D I RDRARM I S S L FDSGKY E IVSLL L QAP K PTAR 638
Cdd:COG5096 521 S I RKA K ----------- Q CNSEL D QDVL R RCFD Y VL V P --------- D L RDRARM Y S R L LSTPLP E FSDPI L CEA K KSNS 580
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 639 SDDF I V SA R L ETH TPE IK E FF R MLP - WN T EI T EVGETGNDI R E GA ELKDYNKY KK SFSSQS FIT N N SAR S ft SSS N AK L T 717
Cdd:COG5096 581 QFEI I L SA L L TNQ TPE LL E NL R LDF t LG T LS T IPLKPIFNL R K GA VVLQQVTV KK PNAELG FIT G N INP S -- GAA N ED L R 658
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|...
gi 398366337 718 G IN DG DS n SI S GK G N VN TF T SQNGKKYR L QSL DEF FSD I P E RKSK P R K IIKVV 770
Cdd:COG5096 659 D IN LN DS - IN S IS G F VN PR T VDEDYFRE L WKM DEF ENK I D E SSNN P K K LDDYS 710
Adaptin_N
pfam01602 Adaptin N terminal region; This family consists of the N terminal region of various alpha, ...
39-622
7.03e-136
Adaptin N terminal region; This family consists of the N terminal region of various alpha, beta and gamma subunits of the AP-1, AP-2 and AP-3 adaptor protein complexes. The adaptor protein (AP) complexes are involved in the formation of clathrin-coated pits and vesicles. The N-terminal region of the various adaptor proteins (APs) is constant by comparison to the C-terminal which is variable within members of the AP-2 family; and it has been proposed that this constant region interacts with another uniform component of the coated vesicles.
Pssm-ID: 396262 [Multi-domain]
Cd Length: 523
Bit Score: 413.17
E-value: 7.03e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 39 SQNINP Q Q L VTL LNS R -- NS R EVRD A M K RIISIMASDD D sid VQLY F AD VVK NITTN D TKV KRL IH LYL LRF AE ND P N L T 116
Cdd:pfam01602 1 EEKRIQ Q E L ARI LNS F rd DP R KKKN A V K KLLYLIMLGE D --- ISFL F FE VVK LVASK D FTL KRL GY LYL MLL AE ES P D L A 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 117 L L SI NS L QK S L SDS N SEL R CF AL SA LS DMKMSS LA PIILHTV KKL VT D P S AM VR GEV ALAI I KLYR AGK n D YHEELLDI L 196
Cdd:pfam01602 78 I L VT NS I QK D L QSP N QLI R GL AL RT LS CIRVPE LA RDLAPDI KKL LV D R S PY VR KKA ALAI L KLYR KSP - D LVRDFVPE L 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 197 KEL MA D T DP K V I S C AV LAYK E - C YA D H L -- E LL HGH FRR Y C RIIKQ L DS W S Q SYLIE LL IKYCKQYLPK P tvvdkssegs 273
Cdd:pfam01602 157 KEL LS D K DP G V Q S A AV ALLY E i C KN D R L yl K LL PLL FRR L C NLLGV L NP W L Q VKILR LL TRLAPLDPLL P ---------- 226
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 274 prscplpdkyneieypsyevvndpdl DLF L QS L NC L IYS SN PT V ILSCC N ALYQ LA SPLQ m KNTKFIE AL V R TVT m TENQ 353
Cdd:pfam01602 227 -------------------------- KEL L ED L LN L LQN SN NA V LYETA N TIVH LA PAPE - LIVLAVN AL G R LLS - SPDE 278
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 354 GNKEML L QAIHFLSILD - QTLFLPYTKK F YVFPK D P I VASIWKIQI L ST L I NESNVKEI F KEL KY YV ASAHF P E n VV I MA 432
Cdd:pfam01602 279 NLRYVA L RNLNKIVMKE p KAVQHLDLII F CLKTD D D I SIRLRALDL L YA L V NESNVKEI V KEL LK YV HEIAD P D - FK I EL 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 433 V KSLS R CGQLSTSWESHVMKW L I D HMESHN ls AS V L D AY V N VIR MLV Q KN P TKHLR I IFK L AD LL TVQT S la DN A R A GIV 512
Cdd:pfam01602 358 V RAIG R LAEKFPTDAEWYLDV L L D LLSLAG -- SY V V D EI V E VIR DII Q NV P ELREY I LEH L CE LL EDIE S -- PE A L A AAL 433
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 513 W LF GE IASIEF -- KIC PD V LR RLIQN F SN E GPET R CQI L VLS AKL lsydidnfkqa QV T GS EE NN QN ppyydfsgsris Q 590
Cdd:pfam01602 434 W IL GE YGELIP ng SSP PD L LR SILEV F VL E SAKV R AAA L TAL AKL ----------- GL T SP EE TT QN ------------ L 490
570 580 590
....*....|....*....|....*....|...
gi 398366337 591 MYNAV L Y LA KY D D - EFDI RDRA RMISS L FDSGK 622
Cdd:pfam01602 491 IIQLL L T LA TQ D S l DLEV RDRA VEYLR L LSLAD 523
PTZ00429
PTZ00429 beta-adaptin; Provisional
51-611
3.71e-23
beta-adaptin; Provisional
Pssm-ID: 240415 [Multi-domain]
Cd Length: 746
Bit Score: 105.40
E-value: 3.71e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 51 LN SRN S REVRD A M KRII SI M ASDD D sid V QLY F A DVVK NITTN D TKV K R L IH LY L L RF A END P NLT LL SI N SLQKSLSD S 130
Cdd:PTZ00429 41 LN GTD S YRKKA A V KRII AN M TMGR D --- V SYL F V DVVK LAPST D LEL K K L VY LY V L ST A RLQ P EKA LL AV N TFLQDTTN S 117
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 131 NSEL R CF A LSALSDMKM SS LAPII L HTVKKL V T DP SAM VR GEV A LAII KL YRAGKN ----- D YHEE L L dilk EL MA D TD P 205
Cdd:PTZ00429 118 SPVV R AL A VRTMMCIRV SS VLEYT L EPLRRA V A DP DPY VR KTA A MGLG KL FHDDMQ lfyqq D FKKD L V ---- EL LN D NN P 193
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 206 K V I S C A --- V LAYKECYADHL E LLHGHFR R YCRIIKQLDS W S Q S Y LI ELL ikyckqylpkptvvdkssegspr SCPL P DK 282
Cdd:PTZ00429 194 V V A S N A aai V CEVNDYGSEKI E SSNEWVN R LVYHLPECNE W G Q L Y IL ELL ----------------------- AAQR P SD 250
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 283 YNEI E ypsyevvndpdl D L FLQS L NCLIY s S NP T V ILSCCNALYQ LAS PLQMKNTKFIEAL V R T VTM T ENQGNK E --- ML 359
Cdd:PTZ00429 251 KESA E ------------ T L LTRV L PRMSH - Q NP A V VMGAIKVVAN LAS RCSQELIERCTVR V N T ALL T LSRRDA E tqy IV 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 360 LQA IH F L SILDQT L FLPYTKK FYV FPK DP IVASIW K IQI L ST L INE S NVK EI F KEL KY Y VASAH -- F PEN VV i M A VK SL S 437
Cdd:PTZ00429 318 CKN IH A L LVIFPN L LRTNLDS FYV RYS DP PFVKLE K LRL L LK L VTP S VAP EI L KEL AE Y ASGVD mv F VVE VV - R A IA SL A 396
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 438 rcgqlstsweshv M K wl I D hmeshnlsa SV LDAYV N VIRML V QKN P ------- T KHLR I IF K LAD LL TVQ T SLA D ----- 505
Cdd:PTZ00429 397 ------------- I K -- V D --------- SV APDCA N LLLQI V DRR P ellpqvv T AAKD I VR K YPE LL MLD T LVT D ygade 452
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 506 ---- N A RAGIV W LF GE IASI e FKICP D VLR R L I QNFSNE gp E T R C Q ILV LSA K llsyd IDN F KQAQVT gseennqnppyy 581
Cdd:PTZ00429 453 vvee E A KVSLL W ML GE YCDF - IENGK D IIQ R F I DTIMEH -- E Q R V Q LAI LSA A ----- VKM F LRDPQG ------------ 512
570 580 590
....*....|....*....|....*....|.
gi 398366337 582 dfsgsr ISQMY N A VL - YLAKYD D EF D I RDRA 611
Cdd:PTZ00429 513 ------ MEPQL N R VL e TVTTHS D DP D V RDRA 537
HEAT
COG1413 HEAT repeat [General function prediction only];
119-214
1.59e-07
HEAT repeat [General function prediction only];
Pssm-ID: 441023 [Multi-domain]
Cd Length: 137
Bit Score: 51.17
E-value: 1.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 119 SINS L QKS L S D SNS E L R CF A LS AL SDMKMSSLA P IIL htvk KLVT D PSAM VR GEV A L A iik L Y R A G kndy HEELLDI L K E 198
Cdd:COG1413 48 AVPA L LEA L K D PDP E V R AA A AE AL GRIGDPEAV P ALI ---- AALK D EDPE VR RAA A E A --- L G R L G ---- DPAAVPA L L E 116
90
....*....|....*.
gi 398366337 199 LMA D T D PK V ISC A VL A 214
Cdd:COG1413 117 ALK D P D WE V RRA A AR A 132
HEAT
COG1413 HEAT repeat [General function prediction only];
119-214
3.93e-06
HEAT repeat [General function prediction only];
Pssm-ID: 441023 [Multi-domain]
Cd Length: 137
Bit Score: 46.93
E-value: 3.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 119 SINS L QKS L S D SNSEL R CF A LS AL SDMKMSSLA P II L htvk KLVT DP SAM VR GEV A L A IIKL yragknd YHE E LLDI L KE 198
Cdd:COG1413 17 AVPA L IAA L A D EDPDV R AA A AR AL GRLGDPRAV P AL L ---- EALK DP DPE VR AAA A E A LGRI ------- GDP E AVPA L IA 85
90
....*....|....*.
gi 398366337 199 LMA D T DP K V ISC A VL A 214
Cdd:COG1413 86 ALK D E DP E V RRA A AE A 101
HEAT_2
pfam13646 HEAT repeats; This family includes multiple HEAT repeats.
123-208
3.35e-05
HEAT repeats; This family includes multiple HEAT repeats.
Pssm-ID: 433376 [Multi-domain]
Cd Length: 88
Bit Score: 43.10
E-value: 3.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 123 LQ KS L S D SNS E L R CF A LS AL SDMKMSSLA P II L htvk K L VT D PSAM VR GEV A L A II K L yragknd YHE E L L DI L K EL MA D 202
Cdd:pfam13646 5 LQ AL L R D PDP E V R AA A IR AL GRIGDPEAV P AL L ---- E L LK D EDPA VR RAA A E A LG K I ------- GDP E A L PA L L EL LR D 73
....*.
gi 398366337 203 T D PK V I 208
Cdd:pfam13646 74 D D DD V V 79
Cnd1
pfam12717 non-SMC mitotic condensation complex subunit 1; The three non-SMC (structural maintenance of ...
134-255
8.53e-05
non-SMC mitotic condensation complex subunit 1; The three non-SMC (structural maintenance of chromosomes) subunits of the mitotic condensation complex are Cnd1-3. The whole complex is essential for viability and the condensing of chromosomes in mitosis.
Pssm-ID: 463677 [Multi-domain]
Cd Length: 162
Bit Score: 43.60
E-value: 8.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 134 L R CF A LSALSDMKMSS L APIILHTVKKLVT D PSAM VR GEV A LAII KL YRAG -- K N dyh EELLDI L KE L MA D TD P K V ISC A 211
Cdd:pfam12717 2 I R AL A IRTMGCIRFPN L VEYLTEPLYRRLK D EDPY VR KTA A MCVA KL ILPD mv K V --- KGFISE L AK L LE D PN P M V VAN A 78
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 398366337 212 VL A YK E CYADH ---- LE LL HGHFRRYCRIIKQLDS W S Q S Y LIEL L IK Y 255
Cdd:pfam12717 79 LA A LT E ISEKD pnai YN LL PDIISKLSDALNECSE W G Q I Y ILDF L AS Y 126
HEAT
COG1413 HEAT repeat [General function prediction only];
20-180
4.54e-04
HEAT repeat [General function prediction only];
Pssm-ID: 441023 [Multi-domain]
Cd Length: 137
Bit Score: 41.15
E-value: 4.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 20 R E AAA V A TSK LG ESSYT yysqninp QQ L VTL L NSRNSREVRD A M -------- K R IISIMAS -- D D DSID V QLYF A DVVKN 89
Cdd:COG1413 2 R R AAA R A LGR LG DPAAV -------- PA L IAA L ADEDPDVRAA A A ralgrlgd P R AVPALLE al K D PDPE V RAAA A EALGR 73
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398366337 90 I ttndtkvkrlihlyllrfae N DP N ltll SINS L QKS L S D SNS E L R CF A LS AL SDMKMSSLA P II L htvk KLVT DP SAM V 169
Cdd:COG1413 74 I -------------------- G DP E ---- AVPA L IAA L K D EDP E V R RA A AE AL GRLGDPAAV P AL L ---- EALK DP DWE V 125
170
....*....|.
gi 398366337 170 R GEV A L A IIK L 180
Cdd:COG1413 126 R RAA A R A LGR L 136
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
