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Conserved domains on  [gi|398364291|ref|NP_012167|]
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glucan 1,4-alpha-glucosidase [Saccharomyces cerevisiae S288C]

Protein Classification

glycoside hydrolase family 15 protein( domain architecture ID 10465003)

glycoside hydrolase family 15 protein similar to glucoamylase (glucan 1,4-alpha-glucosidase) that catalyzes the hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of starch with release of glucose

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glyco_hydro_15 pfam00723
Glycosyl hydrolases family 15; In higher organizms this family is represented by phosphorylase ...
 91-535 2.85e-72

Glycosyl hydrolases family 15; In higher organizms this family is represented by phosphorylase kinase subunits.


:

Pssm-ID: 395586  Cd Length: 417  Bit Score: 236.58  E-value: 2.85e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364291   91 VSIEKIFENIGPS-AVYPSISPGVVIASPSQTHPDYFYQWIRDSALTINSIVSHSAGP-------AIETLLQ-----YLN 157
Cdd:pfam00723   2 IALDAYLRNIGTLkLLIYGPVTGLVIASPSTSLPDYYYTWVRDSALTILALLGLGYRDeddafryGLETSLAklmrgYLQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364291  158 VSFHLQRSNNTLGagigyTNDTVALGDPKWNVDNTAFTED--WGRPQNDGPALRSIAILKIIDyikqsgTDLGAKYpfqs 235
Cdd:pfam00723  82 AMYRQQGKSEPFG-----ERESGGLGEPGFNGDGPVRVGNdaWGRLQLDGPALRALALIQYTA------NGLVIID---- 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364291  236 tadIFDDIVRWDLRFIIDHWNSSGFDLWEEVNGMHFFTLLVQLSAVDKSLSY---FNASERSSPfveeLRQTRRDISKFL 312
Cdd:pfam00723 147 ---TLDEVVKNLLDYVEAAWNEPDFGLWEENGGRSFFSSAMMWKALLEAIDFaelFGDHGSAQL----WESTADEILNKL 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364291  313 VDPanGFINGKYNYIVGTPMIADtlRSGLDISTLLaantvhdAPSASHLPFDinDPAVLNTLHHLMLHMRSIYPINDSSK 392
Cdd:pfam00723 220 QKR--GFWPLFNTYIQLYGSFEY--RSGLDASLLL-------LPILGFDPPD--DPRILATLKYILDSLLSDGFLNSGES 286

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364291  393 NAtgiALGRYPEDVYDGYGFGEGNPWVLATCTASTTLYQLIYRHISEQHDLVVpmnnDCSNAFWSELVFSNLTTLGNDEg 472
Cdd:pfam00723 287 DP---LVRRYPEDVYPDVVGLSGNPWYLCTFWAAEQLYDELYHWAGRGRWTLT----RYARGFFEKLVSSTVGTPYSSS- 358

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 398364291  473 ylilefntpAFNQTIQKIFQLADSFLVKLKAHVGTDGELSEQFNKYTGFMQGAQHLTWSYTSF 535
Cdd:pfam00723 359 ---------SFISIPLAVKEYADGFVKAVEEYANSLGLLSEEVDVYTGEQLGAFPLTFSHAAL 412
 
Name Accession Description Interval E-value
Glyco_hydro_15 pfam00723
Glycosyl hydrolases family 15; In higher organizms this family is represented by phosphorylase ...
 91-535 2.85e-72

Glycosyl hydrolases family 15; In higher organizms this family is represented by phosphorylase kinase subunits.


Pssm-ID: 395586  Cd Length: 417  Bit Score: 236.58  E-value: 2.85e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364291   91 VSIEKIFENIGPS-AVYPSISPGVVIASPSQTHPDYFYQWIRDSALTINSIVSHSAGP-------AIETLLQ-----YLN 157
Cdd:pfam00723   2 IALDAYLRNIGTLkLLIYGPVTGLVIASPSTSLPDYYYTWVRDSALTILALLGLGYRDeddafryGLETSLAklmrgYLQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364291  158 VSFHLQRSNNTLGagigyTNDTVALGDPKWNVDNTAFTED--WGRPQNDGPALRSIAILKIIDyikqsgTDLGAKYpfqs 235
Cdd:pfam00723  82 AMYRQQGKSEPFG-----ERESGGLGEPGFNGDGPVRVGNdaWGRLQLDGPALRALALIQYTA------NGLVIID---- 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364291  236 tadIFDDIVRWDLRFIIDHWNSSGFDLWEEVNGMHFFTLLVQLSAVDKSLSY---FNASERSSPfveeLRQTRRDISKFL 312
Cdd:pfam00723 147 ---TLDEVVKNLLDYVEAAWNEPDFGLWEENGGRSFFSSAMMWKALLEAIDFaelFGDHGSAQL----WESTADEILNKL 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364291  313 VDPanGFINGKYNYIVGTPMIADtlRSGLDISTLLaantvhdAPSASHLPFDinDPAVLNTLHHLMLHMRSIYPINDSSK 392
Cdd:pfam00723 220 QKR--GFWPLFNTYIQLYGSFEY--RSGLDASLLL-------LPILGFDPPD--DPRILATLKYILDSLLSDGFLNSGES 286

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364291  393 NAtgiALGRYPEDVYDGYGFGEGNPWVLATCTASTTLYQLIYRHISEQHDLVVpmnnDCSNAFWSELVFSNLTTLGNDEg 472
Cdd:pfam00723 287 DP---LVRRYPEDVYPDVVGLSGNPWYLCTFWAAEQLYDELYHWAGRGRWTLT----RYARGFFEKLVSSTVGTPYSSS- 358

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 398364291  473 ylilefntpAFNQTIQKIFQLADSFLVKLKAHVGTDGELSEQFNKYTGFMQGAQHLTWSYTSF 535
Cdd:pfam00723 359 ---------SFISIPLAVKEYADGFVKAVEEYANSLGLLSEEVDVYTGEQLGAFPLTFSHAAL 412
 
Name Accession Description Interval E-value
Glyco_hydro_15 pfam00723
Glycosyl hydrolases family 15; In higher organizms this family is represented by phosphorylase ...
 91-535 2.85e-72

Glycosyl hydrolases family 15; In higher organizms this family is represented by phosphorylase kinase subunits.


Pssm-ID: 395586  Cd Length: 417  Bit Score: 236.58  E-value: 2.85e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364291   91 VSIEKIFENIGPS-AVYPSISPGVVIASPSQTHPDYFYQWIRDSALTINSIVSHSAGP-------AIETLLQ-----YLN 157
Cdd:pfam00723   2 IALDAYLRNIGTLkLLIYGPVTGLVIASPSTSLPDYYYTWVRDSALTILALLGLGYRDeddafryGLETSLAklmrgYLQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364291  158 VSFHLQRSNNTLGagigyTNDTVALGDPKWNVDNTAFTED--WGRPQNDGPALRSIAILKIIDyikqsgTDLGAKYpfqs 235
Cdd:pfam00723  82 AMYRQQGKSEPFG-----ERESGGLGEPGFNGDGPVRVGNdaWGRLQLDGPALRALALIQYTA------NGLVIID---- 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364291  236 tadIFDDIVRWDLRFIIDHWNSSGFDLWEEVNGMHFFTLLVQLSAVDKSLSY---FNASERSSPfveeLRQTRRDISKFL 312
Cdd:pfam00723 147 ---TLDEVVKNLLDYVEAAWNEPDFGLWEENGGRSFFSSAMMWKALLEAIDFaelFGDHGSAQL----WESTADEILNKL 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364291  313 VDPanGFINGKYNYIVGTPMIADtlRSGLDISTLLaantvhdAPSASHLPFDinDPAVLNTLHHLMLHMRSIYPINDSSK 392
Cdd:pfam00723 220 QKR--GFWPLFNTYIQLYGSFEY--RSGLDASLLL-------LPILGFDPPD--DPRILATLKYILDSLLSDGFLNSGES 286

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364291  393 NAtgiALGRYPEDVYDGYGFGEGNPWVLATCTASTTLYQLIYRHISEQHDLVVpmnnDCSNAFWSELVFSNLTTLGNDEg 472
Cdd:pfam00723 287 DP---LVRRYPEDVYPDVVGLSGNPWYLCTFWAAEQLYDELYHWAGRGRWTLT----RYARGFFEKLVSSTVGTPYSSS- 358

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 398364291  473 ylilefntpAFNQTIQKIFQLADSFLVKLKAHVGTDGELSEQFNKYTGFMQGAQHLTWSYTSF 535
Cdd:pfam00723 359 ---------SFISIPLAVKEYADGFVKAVEEYANSLGLLSEEVDVYTGEQLGAFPLTFSHAAL 412
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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