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Conserved domains on  [gi|6323097|ref|NP_013169|]
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Fyv7p [Saccharomyces cerevisiae S288C]

Protein Classification

rRNA_processing domain-containing protein( domain architecture ID 12094466)

rRNA_processing domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
rRNA_processing pfam08524
rRNA processing; This is a family of proteins that are involved in rRNA processing. In a ...
8-146 3.92e-31

rRNA processing; This is a family of proteins that are involved in rRNA processing. In a localization study they were found to localize to the nucleus and nucleolus. The family also includes other metazoa members from plants to mammals where the protein has been named BR22 and is associated with TTF-1, thyroid transcription factor 1. In the lungs, the family binds TTF-1 to form a complex which influences the expression of the key lung surfactant protein-B (SP-B) and -C (SP-C), the small hydrophobic surfactant proteins that maintain surface tension in alveoli.


:

Pssm-ID: 400708 [Multi-domain]  Cd Length: 142  Bit Score: 108.93  E-value: 3.92e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323097      8 QNRKKFT-REYKVKEIQRSITKKTRLRKEYLKALKDEGYAVPEKE--PKTVAKESVRKIKEARAIEGKKKLDEKKEIKKQ 84
Cdd:pfam08524   1 KNKKKFTdKEYKSKEIQKSLTRKARLRKEYFKALKKEGYEVPEKAngSNGEEENTSKSLKEARELQGKTKFDERKEIKKE 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6323097     85 RKRMQKDELNKQRNEQLERIRVSKEKFQRREDRKKKLTQRTRTGQPLMGPKIEDLLDKIKTD 146
Cdd:pfam08524  81 RKEEKRERKLEARQKKLERIKALEKKKKEREKRKKQLSKKTKKGQPVMGPRIEDLLDKIKKD 142
 
Name Accession Description Interval E-value
rRNA_processing pfam08524
rRNA processing; This is a family of proteins that are involved in rRNA processing. In a ...
8-146 3.92e-31

rRNA processing; This is a family of proteins that are involved in rRNA processing. In a localization study they were found to localize to the nucleus and nucleolus. The family also includes other metazoa members from plants to mammals where the protein has been named BR22 and is associated with TTF-1, thyroid transcription factor 1. In the lungs, the family binds TTF-1 to form a complex which influences the expression of the key lung surfactant protein-B (SP-B) and -C (SP-C), the small hydrophobic surfactant proteins that maintain surface tension in alveoli.


Pssm-ID: 400708 [Multi-domain]  Cd Length: 142  Bit Score: 108.93  E-value: 3.92e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323097      8 QNRKKFT-REYKVKEIQRSITKKTRLRKEYLKALKDEGYAVPEKE--PKTVAKESVRKIKEARAIEGKKKLDEKKEIKKQ 84
Cdd:pfam08524   1 KNKKKFTdKEYKSKEIQKSLTRKARLRKEYFKALKKEGYEVPEKAngSNGEEENTSKSLKEARELQGKTKFDERKEIKKE 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6323097     85 RKRMQKDELNKQRNEQLERIRVSKEKFQRREDRKKKLTQRTRTGQPLMGPKIEDLLDKIKTD 146
Cdd:pfam08524  81 RKEEKRERKLEARQKKLERIKALEKKKKEREKRKKQLSKKTKKGQPVMGPRIEDLLDKIKKD 142
 
Name Accession Description Interval E-value
rRNA_processing pfam08524
rRNA processing; This is a family of proteins that are involved in rRNA processing. In a ...
8-146 3.92e-31

rRNA processing; This is a family of proteins that are involved in rRNA processing. In a localization study they were found to localize to the nucleus and nucleolus. The family also includes other metazoa members from plants to mammals where the protein has been named BR22 and is associated with TTF-1, thyroid transcription factor 1. In the lungs, the family binds TTF-1 to form a complex which influences the expression of the key lung surfactant protein-B (SP-B) and -C (SP-C), the small hydrophobic surfactant proteins that maintain surface tension in alveoli.


Pssm-ID: 400708 [Multi-domain]  Cd Length: 142  Bit Score: 108.93  E-value: 3.92e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323097      8 QNRKKFT-REYKVKEIQRSITKKTRLRKEYLKALKDEGYAVPEKE--PKTVAKESVRKIKEARAIEGKKKLDEKKEIKKQ 84
Cdd:pfam08524   1 KNKKKFTdKEYKSKEIQKSLTRKARLRKEYFKALKKEGYEVPEKAngSNGEEENTSKSLKEARELQGKTKFDERKEIKKE 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6323097     85 RKRMQKDELNKQRNEQLERIRVSKEKFQRREDRKKKLTQRTRTGQPLMGPKIEDLLDKIKTD 146
Cdd:pfam08524  81 RKEEKRERKLEARQKKLERIKALEKKKKEREKRKKQLSKKTKKGQPVMGPRIEDLLDKIKKD 142
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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