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Conserved domains on  [gi|6323614|ref|NP_013685|]
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Yox1p [Saccharomyces cerevisiae S288C]

Protein Classification

homeobox domain-containing protein( domain architecture ID 11475647)

homeobox domain-containing protein may be involved in the transcriptional regulation of key eukaryotic developmental processes

Gene Ontology:  GO:0003677|GO:0030154|GO:0006357|GO:0000978|GO:0003700
PubMed:  1357790|26464018|27768937|1980756|8768896|11470884

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
126-267 1.24e-40

Homeodomain-containing transcription factor [Transcription];


:

Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 141.03  E-value: 1.24e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323614  126 KKNDILTPLSAAKSIIIPSASKEKRRAFAFITHSQETFPKKEPKIDNAPLARRKRRRTSSQELSILQAEFEKCPAPSKEK 205
Cdd:COG5576   1 SPVQPMQPLSALESQRMPQIRTIKTTKNKREVEAADSEMKLERKQDGSSPPKSKRRRTTDEQLMVLEREFEINPYPSSIT 80

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6323614  206 RIELAESCHMTEKAVQIWFQNKRQAVKRQRIA------TSKSTTIIQTVSPPSPPLDVHATPLASRVK 267
Cdd:COG5576  81 RIKLSLLLNMPPKSVQIWFQNKRAKEKKKRSGkveqrpGEEEADLAKIGSLSTGQISIIETLEFSRTS 148
 
Name Accession Description Interval E-value
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
126-267 1.24e-40

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 141.03  E-value: 1.24e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323614  126 KKNDILTPLSAAKSIIIPSASKEKRRAFAFITHSQETFPKKEPKIDNAPLARRKRRRTSSQELSILQAEFEKCPAPSKEK 205
Cdd:COG5576   1 SPVQPMQPLSALESQRMPQIRTIKTTKNKREVEAADSEMKLERKQDGSSPPKSKRRRTTDEQLMVLEREFEINPYPSSIT 80

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6323614  206 RIELAESCHMTEKAVQIWFQNKRQAVKRQRIA------TSKSTTIIQTVSPPSPPLDVHATPLASRVK 267
Cdd:COG5576  81 RIKLSLLLNMPPKSVQIWFQNKRAKEKKKRSGkveqrpGEEEADLAKIGSLSTGQISIIETLEFSRTS 148
Homeodomain pfam00046
Homeodomain;
177-233 1.08e-18

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 79.08  E-value: 1.08e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 6323614    177 RRKRRRTSSQELSILQAEFEKCPAPSKEKRIELAESCHMTEKAVQIWFQNKRQAVKR 233
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 177-235 3.71e-16

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 71.89  E-value: 3.71e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 6323614  177 RRKRRRTSSQELSILQAEFEKCPAPSKEKRIELAESCHMTEKAVQIWFQNKRQAVKRQR 235
Cdd:cd00086   1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 177-232 1.69e-15

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 70.36  E-value: 1.69e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 6323614     177 RRKRRRTSSQELSILQAEFEKCPAPSKEKRIELAESCHMTEKAVQIWFQNKRQAVK 232
Cdd:smart00389   2 RRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
 
Name Accession Description Interval E-value
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
126-267 1.24e-40

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 141.03  E-value: 1.24e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6323614  126 KKNDILTPLSAAKSIIIPSASKEKRRAFAFITHSQETFPKKEPKIDNAPLARRKRRRTSSQELSILQAEFEKCPAPSKEK 205
Cdd:COG5576   1 SPVQPMQPLSALESQRMPQIRTIKTTKNKREVEAADSEMKLERKQDGSSPPKSKRRRTTDEQLMVLEREFEINPYPSSIT 80

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6323614  206 RIELAESCHMTEKAVQIWFQNKRQAVKRQRIA------TSKSTTIIQTVSPPSPPLDVHATPLASRVK 267
Cdd:COG5576  81 RIKLSLLLNMPPKSVQIWFQNKRAKEKKKRSGkveqrpGEEEADLAKIGSLSTGQISIIETLEFSRTS 148
Homeodomain pfam00046
Homeodomain;
177-233 1.08e-18

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 79.08  E-value: 1.08e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 6323614    177 RRKRRRTSSQELSILQAEFEKCPAPSKEKRIELAESCHMTEKAVQIWFQNKRQAVKR 233
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 177-235 3.71e-16

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 71.89  E-value: 3.71e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 6323614  177 RRKRRRTSSQELSILQAEFEKCPAPSKEKRIELAESCHMTEKAVQIWFQNKRQAVKRQR 235
Cdd:cd00086   1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 177-232 1.69e-15

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 70.36  E-value: 1.69e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 6323614     177 RRKRRRTSSQELSILQAEFEKCPAPSKEKRIELAESCHMTEKAVQIWFQNKRQAVK 232
Cdd:smart00389   2 RRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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