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Conserved domains on  [gi|6324105|ref|NP_014175|]
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Sqs1p [Saccharomyces cerevisiae S288C]

Protein Classification

G patch domain-containing protein( domain architecture ID 10119091)

G patch domain-containing protein similar to Saccharomyces cerevisiae protein PXR1 that is involved in rRNA-processing at A0, A1 and A2 sites through its action in U18 and U24 snoRNA 3'-end final trimming, and pre-mRNA-splicing factor SPP382 that is involved in pre-mRNA splicing and spliceosome disassembly

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
R3H_G-patch cd02646
R3H domain of a group of fungal and plant proteins with unknown function, who also contain a ...
 597-654 2.56e-22

R3H domain of a group of fungal and plant proteins with unknown function, who also contain a G-patch domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the R3H domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


:

Pssm-ID: 100075  Cd Length: 58  Bit Score: 90.71  E-value: 2.56e-22
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 6324105  597 IQNIKDEFESFLSRNNDRLTFPPLDPHGNKTVMKIAKHYNMKSSKIGKANHTSVVVEK 654
Cdd:cd02646   1 IEDIKDEIEAFLLDSRDSLSFPPMDKHGRKTIHKLANCYNLKSKSRGKGKKRFVTVTK 58
G-patch pfam01585
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ...
 721-764 2.38e-14

G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.


:

Pssm-ID: 396249 [Multi-domain]  Cd Length: 45  Bit Score: 67.53  E-value: 2.38e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 6324105    721 ENIGRRMLEKLGWKSGEGLGiQGNKGISEPIFAKIKKNRSGLRH 764
Cdd:pfam01585   2 SNIGFKLLQKMGWKEGQGLG-KNEQGIAEPIEAKIKKDRRGLGA 44
 
Name Accession Description Interval E-value
R3H_G-patch cd02646
R3H domain of a group of fungal and plant proteins with unknown function, who also contain a ...
 597-654 2.56e-22

R3H domain of a group of fungal and plant proteins with unknown function, who also contain a G-patch domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the R3H domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100075  Cd Length: 58  Bit Score: 90.71  E-value: 2.56e-22
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 6324105  597 IQNIKDEFESFLSRNNDRLTFPPLDPHGNKTVMKIAKHYNMKSSKIGKANHTSVVVEK 654
Cdd:cd02646   1 IEDIKDEIEAFLLDSRDSLSFPPMDKHGRKTIHKLANCYNLKSKSRGKGKKRFVTVTK 58
G-patch pfam01585
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ...
 721-764 2.38e-14

G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.


Pssm-ID: 396249 [Multi-domain]  Cd Length: 45  Bit Score: 67.53  E-value: 2.38e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 6324105    721 ENIGRRMLEKLGWKSGEGLGiQGNKGISEPIFAKIKKNRSGLRH 764
Cdd:pfam01585   2 SNIGFKLLQKMGWKEGQGLG-KNEQGIAEPIEAKIKKDRRGLGA 44
G_patch smart00443
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ...
 718-765 9.53e-14

glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.


Pssm-ID: 197727 [Multi-domain]  Cd Length: 47  Bit Score: 66.03  E-value: 9.53e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 6324105     718 IGNENIGRRMLEKLGWKSGEGLGIQgNKGISEPIFAKIKKNRSGLRHS 765
Cdd:smart00443   1 ISTSNIGAKLLRKMGWKEGQGLGKN-EQGIVEPISAEIKKDRKGLGAV 47
R3H pfam01424
R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most ...
 597-654 8.73e-05

R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to be binding ssDNA.


Pssm-ID: 460206  Cd Length: 60  Bit Score: 40.94  E-value: 8.73e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 6324105    597 IQNIKDEFESFLSRNNDRLTFPPLDPHGNKTVMKIAKHYNMKSSKIGKANHTSVVVEK 654
Cdd:pfam01424   3 LEQLAEKLAEFVKDTGKSLELPPMSSYERRIIHELAQKYGLESESEGEEPNRRVVVYK 60
 
Name Accession Description Interval E-value
R3H_G-patch cd02646
R3H domain of a group of fungal and plant proteins with unknown function, who also contain a ...
 597-654 2.56e-22

R3H domain of a group of fungal and plant proteins with unknown function, who also contain a G-patch domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the R3H domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100075  Cd Length: 58  Bit Score: 90.71  E-value: 2.56e-22
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 6324105  597 IQNIKDEFESFLSRNNDRLTFPPLDPHGNKTVMKIAKHYNMKSSKIGKANHTSVVVEK 654
Cdd:cd02646   1 IEDIKDEIEAFLLDSRDSLSFPPMDKHGRKTIHKLANCYNLKSKSRGKGKKRFVTVTK 58
G-patch pfam01585
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ...
 721-764 2.38e-14

G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.


Pssm-ID: 396249 [Multi-domain]  Cd Length: 45  Bit Score: 67.53  E-value: 2.38e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 6324105    721 ENIGRRMLEKLGWKSGEGLGiQGNKGISEPIFAKIKKNRSGLRH 764
Cdd:pfam01585   2 SNIGFKLLQKMGWKEGQGLG-KNEQGIAEPIEAKIKKDRRGLGA 44
G_patch smart00443
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ...
 718-765 9.53e-14

glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.


Pssm-ID: 197727 [Multi-domain]  Cd Length: 47  Bit Score: 66.03  E-value: 9.53e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 6324105     718 IGNENIGRRMLEKLGWKSGEGLGIQgNKGISEPIFAKIKKNRSGLRHS 765
Cdd:smart00443   1 ISTSNIGAKLLRKMGWKEGQGLGKN-EQGIVEPISAEIKKDRKGLGAV 47
R3H cd02325
R3H domain. The name of the R3H domain comes from the characteristic spacing of the most ...
 597-654 1.35e-08

R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. R3H domains are found in proteins together with ATPase domains, SF1 helicase domains, SF2 DEAH helicase domains, Cys-rich repeats, ring-type zinc fingers, and KH domains. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100064  Cd Length: 59  Bit Score: 51.46  E-value: 1.35e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 6324105  597 IQNIKDEFESFLSRNN-DRLTFPPLDPHGNKTVMKIAKHYNMKSSKIGKANHTSVVVEK 654
Cdd:cd02325   1 REEREEELEAFAKDAAgKSLELPPMNSYERKLIHDLAEYYGLKSESEGEGPNRRVVITK 59
R3H pfam01424
R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most ...
 597-654 8.73e-05

R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to be binding ssDNA.


Pssm-ID: 460206  Cd Length: 60  Bit Score: 40.94  E-value: 8.73e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 6324105    597 IQNIKDEFESFLSRNNDRLTFPPLDPHGNKTVMKIAKHYNMKSSKIGKANHTSVVVEK 654
Cdd:pfam01424   3 LEQLAEKLAEFVKDTGKSLELPPMSSYERRIIHELAQKYGLESESEGEEPNRRVVVYK 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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