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Hsp90 family chaperone HSP82 [Saccharomyces cerevisiae S288C]
Protein Classification
HSP90 family protein ( domain architecture ID 1903338 )
HSP90 (heat shock protein 90) family protein functions as a molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved in cell cycle control and signal transduction
List of domain hits
Name
Accession
Description
Interval
E-value
HSP90 super family
cl46693 Hsp90 protein;
3-709
0e+00
Hsp90 protein;
PTZ00272 :Pssm-ID: 481033
Cd Length: 701
Bit Score: 875.93
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 3 S ETF E FQAEI T QLMSLIINT V YSNKEIFLRELISNASDA L DKIRY K SL S DP KQ L ETE P D L F IR IT P KP E Q K V L EIR D S GI 82
Cdd:PTZ00272 2 T ETF A FQAEI N QLMSLIINT F YSNKEIFLRELISNASDA C DKIRY Q SL T DP SV L GES P R L C IR VV P DK E N K T L TVE D N GI 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 83 GMTKA E L I NNLGTIA K SGTKAFMEAL S AG A D V SMIGQFGVGFYS LF LVADRV Q V I SK S N D DE Q Y I WES N AGG S FT V T l DE 162
Cdd:PTZ00272 82 GMTKA D L V NNLGTIA R SGTKAFMEAL E AG G D M SMIGQFGVGFYS AY LVADRV T V T SK N N S DE S Y V WES S AGG T FT I T - ST 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 163 VNERIG RGT ILR L F LK D DQ L EYLE EK R I KE V IK R HSEF VA Y P I Q L V V T K EV EKEV pipeeek K DE EKK D EE K K DED DKK P 242
Cdd:PTZ00272 161 PESDMK RGT RIT L H LK E DQ M EYLE PR R L KE L IK K HSEF IG Y D I E L M V E K TT EKEV ------- T DE DEE D TK K A DED GEE P 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 243 K L EEV D E EE E K K P K TK K VKE EV - Q E I E EL NK T KPLWTR N P S D I T Q EEY N AFYK S ISNDWEDP LYV KHFSVEGQLEFR A I L 321
Cdd:PTZ00272 234 K V EEV K E GD E G K K K KT K KVK EV t K E Y E VQ NK H KPLWTR D P K D V T K EEY A AFYK A ISNDWEDP AAT KHFSVEGQLEFR S I M 313
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 322 F I PKRAPFD L FE SK KK K NNIKLYVRRVFI T D EA EDL I P E WL S FVKGVVDSEDLPLN L SRE M LQQNKI M KVIRKNIVKK LI 401
Cdd:PTZ00272 314 F V PKRAPFD M FE PN KK R NNIKLYVRRVFI M D NC EDL C P D WL G FVKGVVDSEDLPLN I SRE N LQQNKI L KVIRKNIVKK CL 393
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 402 E A F N E I AE DS E QFEK FY SA F S KNIKLG V HEDT Q NR AA L AK LLR YN ST K S VD E L T S L T DYVTRM PEH QK N IYYITG E S L K A 481
Cdd:PTZ00272 394 E M F D E V AE NK E DYKQ FY EQ F G KNIKLG I HEDT A NR KK L ME LLR FY ST E S GE E M T T L K DYVTRM KAG QK S IYYITG D S K K K 473
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 482 V E K SPF LDALKAKNF EVLF L T D PIDEY AFT Q L K E FE G K TLVDI TK D - FEL EE TD EEK AE RE K E IKEY E P L T K AL KE I LGD 560
Cdd:PTZ00272 474 L E T SPF IEQARRRGL EVLF M T E PIDEY VMQ Q V K D FE D K KFACL TK E g VHF EE SE EEK QQ RE E E KAAC E K L C K TM KE V LGD 553
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 561 Q VEKV V VS YK L LDA P AAIR T GQ FGWSA N ME R IM KA QALRDSSM SS YM S SKKT F E IS P KS PIIKEL KK RV d EGGAQ DK T VK 640
Cdd:PTZ00272 554 K VEKV I VS ER L STS P CILV T SE FGWSA H ME Q IM RN QALRDSSM AQ YM M SKKT M E LN P RH PIIKEL RR RV - GADEN DK A VK 632
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6325016 641 DL TK LL YE T A LLTSGF S L DE PT SF A S RINR L I S LGL NI DE D EE TETAPEASTA AP V E EVPADTE ME E VD 709
Cdd:PTZ00272 633 DL VF LL FD T S LLTSGF Q L ED PT GY A E RINR M I K LGL SL DE E EE EAAEAPVAET AP A E VTAGTSS ME Q VD 701
Name
Accession
Description
Interval
E-value
PTZ00272
PTZ00272 heat shock protein 83 kDa (Hsp83); Provisional
3-709
0e+00
heat shock protein 83 kDa (Hsp83); Provisional
Pssm-ID: 240341
Cd Length: 701
Bit Score: 875.93
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 3 S ETF E FQAEI T QLMSLIINT V YSNKEIFLRELISNASDA L DKIRY K SL S DP KQ L ETE P D L F IR IT P KP E Q K V L EIR D S GI 82
Cdd:PTZ00272 2 T ETF A FQAEI N QLMSLIINT F YSNKEIFLRELISNASDA C DKIRY Q SL T DP SV L GES P R L C IR VV P DK E N K T L TVE D N GI 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 83 GMTKA E L I NNLGTIA K SGTKAFMEAL S AG A D V SMIGQFGVGFYS LF LVADRV Q V I SK S N D DE Q Y I WES N AGG S FT V T l DE 162
Cdd:PTZ00272 82 GMTKA D L V NNLGTIA R SGTKAFMEAL E AG G D M SMIGQFGVGFYS AY LVADRV T V T SK N N S DE S Y V WES S AGG T FT I T - ST 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 163 VNERIG RGT ILR L F LK D DQ L EYLE EK R I KE V IK R HSEF VA Y P I Q L V V T K EV EKEV pipeeek K DE EKK D EE K K DED DKK P 242
Cdd:PTZ00272 161 PESDMK RGT RIT L H LK E DQ M EYLE PR R L KE L IK K HSEF IG Y D I E L M V E K TT EKEV ------- T DE DEE D TK K A DED GEE P 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 243 K L EEV D E EE E K K P K TK K VKE EV - Q E I E EL NK T KPLWTR N P S D I T Q EEY N AFYK S ISNDWEDP LYV KHFSVEGQLEFR A I L 321
Cdd:PTZ00272 234 K V EEV K E GD E G K K K KT K KVK EV t K E Y E VQ NK H KPLWTR D P K D V T K EEY A AFYK A ISNDWEDP AAT KHFSVEGQLEFR S I M 313
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 322 F I PKRAPFD L FE SK KK K NNIKLYVRRVFI T D EA EDL I P E WL S FVKGVVDSEDLPLN L SRE M LQQNKI M KVIRKNIVKK LI 401
Cdd:PTZ00272 314 F V PKRAPFD M FE PN KK R NNIKLYVRRVFI M D NC EDL C P D WL G FVKGVVDSEDLPLN I SRE N LQQNKI L KVIRKNIVKK CL 393
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 402 E A F N E I AE DS E QFEK FY SA F S KNIKLG V HEDT Q NR AA L AK LLR YN ST K S VD E L T S L T DYVTRM PEH QK N IYYITG E S L K A 481
Cdd:PTZ00272 394 E M F D E V AE NK E DYKQ FY EQ F G KNIKLG I HEDT A NR KK L ME LLR FY ST E S GE E M T T L K DYVTRM KAG QK S IYYITG D S K K K 473
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 482 V E K SPF LDALKAKNF EVLF L T D PIDEY AFT Q L K E FE G K TLVDI TK D - FEL EE TD EEK AE RE K E IKEY E P L T K AL KE I LGD 560
Cdd:PTZ00272 474 L E T SPF IEQARRRGL EVLF M T E PIDEY VMQ Q V K D FE D K KFACL TK E g VHF EE SE EEK QQ RE E E KAAC E K L C K TM KE V LGD 553
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 561 Q VEKV V VS YK L LDA P AAIR T GQ FGWSA N ME R IM KA QALRDSSM SS YM S SKKT F E IS P KS PIIKEL KK RV d EGGAQ DK T VK 640
Cdd:PTZ00272 554 K VEKV I VS ER L STS P CILV T SE FGWSA H ME Q IM RN QALRDSSM AQ YM M SKKT M E LN P RH PIIKEL RR RV - GADEN DK A VK 632
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6325016 641 DL TK LL YE T A LLTSGF S L DE PT SF A S RINR L I S LGL NI DE D EE TETAPEASTA AP V E EVPADTE ME E VD 709
Cdd:PTZ00272 633 DL VF LL FD T S LLTSGF Q L ED PT GY A E RINR M I K LGL SL DE E EE EAAEAPVAET AP A E VTAGTSS ME Q VD 701
HSP90
pfam00183 Hsp90 protein;
183-707
0e+00
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 772.50
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 183 EYLEEK R IKE VI K RH SEF VAY PI Q L V V T KE V E K EVP IP EEE KKD EE KKD E EKKDEDDKK pkleevd E EEE K K P KTKKVKE 262
Cdd:pfam00183 1 EYLEEK K IKE LV K KY SEF INF PI Y L W V E KE E E V EVP DE EEE EEE EE EEE E DDDPKVEEE ------- D EEE E K K KTKKVKE 73
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 263 E V Q E I E E LNKTKP L WTRNP SDI T Q EEY NA FYKS I S N DWEDPL Y VKHFSVEG QL EF RAI LFIPKRAPFDLFE S KKKKNNIK 342
Cdd:pfam00183 74 T V W E W E L LNKTKP I WTRNP KEV T E EEY AE FYKS L S K DWEDPL A VKHFSVEG EV EF KSL LFIPKRAPFDLFE N KKKKNNIK 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 343 LYVRRVFITD EA EDLIPE W L S FVKGVVDS E DLPLN L SRE M LQQNKI M KVI R K NI V K K LIEA F N EIAE DS E QFE KF YSA F S 422
Cdd:pfam00183 154 LYVRRVFITD DF EDLIPE Y L N FVKGVVDS D DLPLN V SRE T LQQNKI L KVI K K KL V R K ALDM F K EIAE EK E DYK KF WKE F G 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 423 KN I KLG VH ED TQ NR AA LAKLLR YN S T KS V DELTSL T DYV T RM P E H QK N IYYITGES LKA VE K SPFL DA LK A K NF EVL F LT 502
Cdd:pfam00183 234 KN L KLG II ED SS NR NK LAKLLR FY S S KS G DELTSL D DYV S RM K E G QK H IYYITGES KEE VE N SPFL ER LK K K GY EVL Y LT 313
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 503 DPIDEYA FT QLKEF E GK T LV DIT K - DF ELEE TD EEK AER E KEI KE Y EPLTK A LK EI LGD Q VEKVVVS YK L L D A P AAIR T G 581
Cdd:pfam00183 314 DPIDEYA VQ QLKEF D GK K LV NVA K e GL ELEE DE EEK KKD E ELK KE F EPLTK W LK DV LGD K VEKVVVS NR L V D S P CVLV T S 393
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 582 Q F GWSANMERIMKAQALR - DSSMSSYMSSKKT F EI S P KS PIIKEL K KRV DE g GAQ DKT V KDL TK LLYETALL T SGFSL DE 660
Cdd:pfam00183 394 Q Y GWSANMERIMKAQALR k DSSMSSYMSSKKT L EI N P RH PIIKEL L KRV EA - DKD DKT A KDL AL LLYETALL R SGFSL ED 472
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 6325016 661 P T SFASRI N R LIS LGL N IDEDE ET E TAP E AST aap V EE VPADTEM EE 707
Cdd:pfam00183 473 P A SFASRI Y R MLK LGL G IDEDE IV E EED E IEE --- E EE EEEEEPE EE 516
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
1-677
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 743.86
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 1 MA S ET F EFQAE IT QL MS L I I NTV YSNKEIFLRELISNASDA L DK I R YKS L S DP KQL E TEP DL F IRI TPKP E Q K V L E I R D S 80
Cdd:COG0326 1 MA K ET G EFQAE VK QL LD L M I HSL YSNKEIFLRELISNASDA I DK L R FLA L T DP ELK E EDG DL K IRI EVDK E A K T L T I S D N 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 81 GIGMT KA E L I N NLGTIAKSGT KA F M E A L S -- AGA D VSM IGQFGVGFYS L F L VAD R V Q V ISK S -- N D D E QYI WES NAG G SF 156
Cdd:COG0326 81 GIGMT RE E V I E NLGTIAKSGT RE F L E K L K gd QKK D SDL IGQFGVGFYS A F M VAD K V E V VTR S ag E D A E AVR WES DGD G EY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 157 T V tld E VN E RIG RGT ILR L F LK D D QL E Y LEE K R IK E V IK RH S E F VAY PI QLVVTK E VEK E V pipeeekkdeekkdeekkd 236
Cdd:COG0326 161 T I --- E EA E KAE RGT EIT L H LK E D AE E F LEE W R LR E I IK KY S D F IPV PI KMEGEE E ETE E D ------------------- 218
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 237 eddkkpkleevdeeeekkpktkkvkeevqei E EL N KTKP LWTR NP S D IT Q EEY NA FYK SISN D W EDPL YVK H FS VEG QL E 316
Cdd:COG0326 219 ------------------------------- E TI N SATA LWTR SK S E IT D EEY KE FYK HLFH D F EDPL FWI H LN VEG PF E 267
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 317 FRAI L F IPK R APFDL FE s KKK K NN IKLYV R RVFI T D E AEDL I PE W L S FV K GVVDS E DLPLN L SRE M LQ QNKIM K V IRK N I 396
Cdd:COG0326 268 YTGL L Y IPK K APFDL YD - RDR K GG IKLYV K RVFI M D D AEDL L PE Y L R FV R GVVDS P DLPLN V SRE I LQ EDRQL K K IRK A I 346
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 397 V KK LIEAFNEI A E - D S E QF EKF YSA F SKNI K L G VH ED TQ NR AAL A K LLR YN STK S v DELTS L TD YV T RM P E H QK N IYYIT 475
Cdd:COG0326 347 T KK VLDELEKL A K n D R E KY EKF WKE F GLVL K E G AL ED FK NR EKI A D LLR FE STK E - GGYVT L AE YV E RM K E G QK K IYYIT 425
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 476 GES LK A V E K SP F L DAL KAK NF EVL F LTDPIDE YAFTQ L K EF E GK TLVDITK - D FE L EE t D EEK A E R E K E IK E YE PL TKAL 554
Cdd:COG0326 426 GES RE A A E Q SP H L EIF KAK GI EVL L LTDPIDE FLISH L E EF D GK KFKSVDS g D LD L DK - L EEK K E S E E E EE E FK PL LERF 504
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 555 KE I LGD Q V EK V V VS YK L L D A PA AIRTGQFGW S AN ME RIM KA QA lrdssm SSYMSS K KTF EI S P KS P II K E L KKRV DE gga 634
Cdd:COG0326 505 KE A LGD K V KD V R VS AR L T D S PA CLVADEGDM S RR ME KML KA MG ------ QDMPEA K PIL EI N P NH P LV K K L AAEE DE --- 575
650 660 670 680
....*....|....*....|....*....|....*....|...
gi 6325016 635 qd KTV KDL TK LLY ET ALL TS G FS L DE P TS F AS R I N R L ISLG L N 677
Cdd:COG0326 576 -- ELF KDL AE LLY DQ ALL AE G GL L ED P AA F VK R L N K L LEKA L G 616
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
14-201
2.13e-103
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 313.69
E-value: 2.13e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 14 QL MS LII NTV YSNKEIFLRELISNASDALDK I RY K SL S DP KQ L ETE P D L F IRI T P KP E QKV L E I R D S GIGMTK A ELINNL 93
Cdd:cd16927 2 QL LD LII HSL YSNKEIFLRELISNASDALDK L RY L SL T DP SL L DDD P E L E IRI S P DK E NRT L T I S D T GIGMTK E ELINNL 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 94 GTIA K SGTKAF M EAL SA GA - D VSM IGQFGVGFYS L F L VAD R V Q V IS KS N - DDE Q Y I WES NA GGS F T VT ld E VNERI GRGT 171
Cdd:cd16927 82 GTIA R SGTKAF L EAL QE GA k D SDL IGQFGVGFYS A F M VAD K V T V TT KS A g DDE G Y R WES DG GGS Y T IE -- E AEGEL GRGT 159
170 180 190
....*....|....*....|....*....|
gi 6325016 172 ILR L F LK D D QL E Y LEE K RIKE VI K RH S E F V 201
Cdd:cd16927 160 KIT L H LK E D AK E F LEE A RIKE LV K KY S D F I 189
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
26-161
1.05e-09
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 56.50
E-value: 1.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 26 NKEIF LR ELI SN AS D AL dk I R Y K slsdpkql ETEPDLFIRITPKPEQKVLEIR D S G I G MTKAE L innlgtiaksg T K A F M 105
Cdd:smart00387 1 GDPDR LR QVL SN LL D NA -- I K Y T -------- PEGGRITVTLERDGDHVEITVE D N G P G IPPED L ----------- E K I F E 59
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 6325016 106 EALSAGADVSM IG QF G V G FYSLFLVADRVQV - IS KSNDDEQ yiwesna G GS FT V TL D 161
Cdd:smart00387 60 PFFRTDKRSRK IG GT G L G LSIVKKLVELHGG e IS VESEPGG ------- G TT FT I TL P 109
Name
Accession
Description
Interval
E-value
PTZ00272
PTZ00272 heat shock protein 83 kDa (Hsp83); Provisional
3-709
0e+00
heat shock protein 83 kDa (Hsp83); Provisional
Pssm-ID: 240341
Cd Length: 701
Bit Score: 875.93
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 3 S ETF E FQAEI T QLMSLIINT V YSNKEIFLRELISNASDA L DKIRY K SL S DP KQ L ETE P D L F IR IT P KP E Q K V L EIR D S GI 82
Cdd:PTZ00272 2 T ETF A FQAEI N QLMSLIINT F YSNKEIFLRELISNASDA C DKIRY Q SL T DP SV L GES P R L C IR VV P DK E N K T L TVE D N GI 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 83 GMTKA E L I NNLGTIA K SGTKAFMEAL S AG A D V SMIGQFGVGFYS LF LVADRV Q V I SK S N D DE Q Y I WES N AGG S FT V T l DE 162
Cdd:PTZ00272 82 GMTKA D L V NNLGTIA R SGTKAFMEAL E AG G D M SMIGQFGVGFYS AY LVADRV T V T SK N N S DE S Y V WES S AGG T FT I T - ST 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 163 VNERIG RGT ILR L F LK D DQ L EYLE EK R I KE V IK R HSEF VA Y P I Q L V V T K EV EKEV pipeeek K DE EKK D EE K K DED DKK P 242
Cdd:PTZ00272 161 PESDMK RGT RIT L H LK E DQ M EYLE PR R L KE L IK K HSEF IG Y D I E L M V E K TT EKEV ------- T DE DEE D TK K A DED GEE P 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 243 K L EEV D E EE E K K P K TK K VKE EV - Q E I E EL NK T KPLWTR N P S D I T Q EEY N AFYK S ISNDWEDP LYV KHFSVEGQLEFR A I L 321
Cdd:PTZ00272 234 K V EEV K E GD E G K K K KT K KVK EV t K E Y E VQ NK H KPLWTR D P K D V T K EEY A AFYK A ISNDWEDP AAT KHFSVEGQLEFR S I M 313
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 322 F I PKRAPFD L FE SK KK K NNIKLYVRRVFI T D EA EDL I P E WL S FVKGVVDSEDLPLN L SRE M LQQNKI M KVIRKNIVKK LI 401
Cdd:PTZ00272 314 F V PKRAPFD M FE PN KK R NNIKLYVRRVFI M D NC EDL C P D WL G FVKGVVDSEDLPLN I SRE N LQQNKI L KVIRKNIVKK CL 393
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 402 E A F N E I AE DS E QFEK FY SA F S KNIKLG V HEDT Q NR AA L AK LLR YN ST K S VD E L T S L T DYVTRM PEH QK N IYYITG E S L K A 481
Cdd:PTZ00272 394 E M F D E V AE NK E DYKQ FY EQ F G KNIKLG I HEDT A NR KK L ME LLR FY ST E S GE E M T T L K DYVTRM KAG QK S IYYITG D S K K K 473
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 482 V E K SPF LDALKAKNF EVLF L T D PIDEY AFT Q L K E FE G K TLVDI TK D - FEL EE TD EEK AE RE K E IKEY E P L T K AL KE I LGD 560
Cdd:PTZ00272 474 L E T SPF IEQARRRGL EVLF M T E PIDEY VMQ Q V K D FE D K KFACL TK E g VHF EE SE EEK QQ RE E E KAAC E K L C K TM KE V LGD 553
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 561 Q VEKV V VS YK L LDA P AAIR T GQ FGWSA N ME R IM KA QALRDSSM SS YM S SKKT F E IS P KS PIIKEL KK RV d EGGAQ DK T VK 640
Cdd:PTZ00272 554 K VEKV I VS ER L STS P CILV T SE FGWSA H ME Q IM RN QALRDSSM AQ YM M SKKT M E LN P RH PIIKEL RR RV - GADEN DK A VK 632
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6325016 641 DL TK LL YE T A LLTSGF S L DE PT SF A S RINR L I S LGL NI DE D EE TETAPEASTA AP V E EVPADTE ME E VD 709
Cdd:PTZ00272 633 DL VF LL FD T S LLTSGF Q L ED PT GY A E RINR M I K LGL SL DE E EE EAAEAPVAET AP A E VTAGTSS ME Q VD 701
HSP90
pfam00183 Hsp90 protein;
183-707
0e+00
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 772.50
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 183 EYLEEK R IKE VI K RH SEF VAY PI Q L V V T KE V E K EVP IP EEE KKD EE KKD E EKKDEDDKK pkleevd E EEE K K P KTKKVKE 262
Cdd:pfam00183 1 EYLEEK K IKE LV K KY SEF INF PI Y L W V E KE E E V EVP DE EEE EEE EE EEE E DDDPKVEEE ------- D EEE E K K KTKKVKE 73
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 263 E V Q E I E E LNKTKP L WTRNP SDI T Q EEY NA FYKS I S N DWEDPL Y VKHFSVEG QL EF RAI LFIPKRAPFDLFE S KKKKNNIK 342
Cdd:pfam00183 74 T V W E W E L LNKTKP I WTRNP KEV T E EEY AE FYKS L S K DWEDPL A VKHFSVEG EV EF KSL LFIPKRAPFDLFE N KKKKNNIK 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 343 LYVRRVFITD EA EDLIPE W L S FVKGVVDS E DLPLN L SRE M LQQNKI M KVI R K NI V K K LIEA F N EIAE DS E QFE KF YSA F S 422
Cdd:pfam00183 154 LYVRRVFITD DF EDLIPE Y L N FVKGVVDS D DLPLN V SRE T LQQNKI L KVI K K KL V R K ALDM F K EIAE EK E DYK KF WKE F G 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 423 KN I KLG VH ED TQ NR AA LAKLLR YN S T KS V DELTSL T DYV T RM P E H QK N IYYITGES LKA VE K SPFL DA LK A K NF EVL F LT 502
Cdd:pfam00183 234 KN L KLG II ED SS NR NK LAKLLR FY S S KS G DELTSL D DYV S RM K E G QK H IYYITGES KEE VE N SPFL ER LK K K GY EVL Y LT 313
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 503 DPIDEYA FT QLKEF E GK T LV DIT K - DF ELEE TD EEK AER E KEI KE Y EPLTK A LK EI LGD Q VEKVVVS YK L L D A P AAIR T G 581
Cdd:pfam00183 314 DPIDEYA VQ QLKEF D GK K LV NVA K e GL ELEE DE EEK KKD E ELK KE F EPLTK W LK DV LGD K VEKVVVS NR L V D S P CVLV T S 393
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 582 Q F GWSANMERIMKAQALR - DSSMSSYMSSKKT F EI S P KS PIIKEL K KRV DE g GAQ DKT V KDL TK LLYETALL T SGFSL DE 660
Cdd:pfam00183 394 Q Y GWSANMERIMKAQALR k DSSMSSYMSSKKT L EI N P RH PIIKEL L KRV EA - DKD DKT A KDL AL LLYETALL R SGFSL ED 472
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 6325016 661 P T SFASRI N R LIS LGL N IDEDE ET E TAP E AST aap V EE VPADTEM EE 707
Cdd:pfam00183 473 P A SFASRI Y R MLK LGL G IDEDE IV E EED E IEE --- E EE EEEEEPE EE 516
PRK05218
PRK05218 heat shock protein 90; Provisional
1-677
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 756.18
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 1 MA S ET F EFQAE IT QL MS L I I NTV YSNKEIFLRELISNASDA L DK I R YKS L S DP KQL E TEP DL F IRI TPKP E QKV L E I R D S 80
Cdd:PRK05218 1 MA M ET G EFQAE VK QL LH L M I HSL YSNKEIFLRELISNASDA I DK L R FEA L T DP ALY E GDG DL K IRI SFDK E ART L T I S D N 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 81 GIGMT KA E L I N NLGTIAKSGTK A F M E A L S -- AGA D VSM IGQFGVGFYS L F L VAD R V Q VI SK S -- NDD E QYI WES NAG G SF 156
Cdd:PRK05218 81 GIGMT RE E V I E NLGTIAKSGTK E F L E K L K gd QKK D SQL IGQFGVGFYS A F M VAD K V T VI TR S ag PAA E AVR WES DGE G EY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 157 T V tl D E V n E RIG RGT ILR L F LK D D QL E Y L E E K RI KEV IK RH S E F VAY PI Q L VVTK E vekevpipeeekkdeekkdeekkd 236
Cdd:PRK05218 161 T I -- E E I - E KEE RGT EIT L H LK E D ED E F L D E W RI RSI IK KY S D F IPV PI K L EKEE E ------------------------ 213
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 237 eddkkpkleevdeeeekkpktkkvkeevqei E EL N KTKP LWTR NP S D IT Q EEY NA FYK SISN D WE DPL YVK H FS VEG QL E 316
Cdd:PRK05218 214 ------------------------------- E TI N SASA LWTR SK S E IT D EEY KE FYK HLAH D FD DPL FWI H NN VEG PF E 262
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 317 FRAI L F IPK R APFDLF E s KKK K NNI KLYV R RVFI T D E AE D L I PE W L S FVKGV V DSEDLPLN L SRE M LQ QNKIM K V IRK N I 396
Cdd:PRK05218 263 YTGL L Y IPK K APFDLF N - RDR K GGL KLYV K RVFI M D D AE E L L PE Y L R FVKGV I DSEDLPLN V SRE I LQ EDRVV K K IRK A I 341
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 397 V KK LIEAFNEI A E - D S E QF EKF YSA F SKNI K L G VH ED TQ NR AA LAKLLR YN ST KS v DELT SL TD YV T RM P E H QK N IYYIT 475
Cdd:PRK05218 342 T KK VLDELEKL A K n D R E KY EKF WKE F GPVL K E G LY ED FA NR EK LAKLLR FA ST HE - GKYV SL AE YV E RM K E G QK K IYYIT 420
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 476 G E S LK A VEK SP F L DAL K A K NF EVL F LTDPIDE YAFTQ L K EF E GK TLVDITK - D FE L EET DEE KA E REK E I - K E YE PL TKA 553
Cdd:PRK05218 421 G D S RE A AKN SP H L ELF K K K GI EVL L LTDPIDE FWISY L E EF D GK PFKSVAR g D LD L GKE DEE EK E EKE E A e E E FK PL LER 500
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 554 LKE I LGD Q V EK V VV S YK L L D A PA AIRTGQFGW S AN ME RIM KA Q alrdss MSSYMS SK KTF EI S P KS P II K E L KKRV DE gg 633
Cdd:PRK05218 501 LKE A LGD K V KD V RL S HR L T D S PA CLVADEGDM S TQ ME KLL KA A ------ GQEVPE SK PIL EI N P NH P LV K K L ADEA DE -- 572
650 660 670 680
....*....|....*....|....*....|....*....|....
gi 6325016 634 aqd KTV KDL TK LLY ET ALL TS G F SL DE P TS F AS R I N R L ISLG L N 677
Cdd:PRK05218 573 --- AKF KDL AE LLY DQ ALL AE G G SL ED P AA F VK R L N E L LLKL L A 613
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
1-677
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 743.86
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 1 MA S ET F EFQAE IT QL MS L I I NTV YSNKEIFLRELISNASDA L DK I R YKS L S DP KQL E TEP DL F IRI TPKP E Q K V L E I R D S 80
Cdd:COG0326 1 MA K ET G EFQAE VK QL LD L M I HSL YSNKEIFLRELISNASDA I DK L R FLA L T DP ELK E EDG DL K IRI EVDK E A K T L T I S D N 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 81 GIGMT KA E L I N NLGTIAKSGT KA F M E A L S -- AGA D VSM IGQFGVGFYS L F L VAD R V Q V ISK S -- N D D E QYI WES NAG G SF 156
Cdd:COG0326 81 GIGMT RE E V I E NLGTIAKSGT RE F L E K L K gd QKK D SDL IGQFGVGFYS A F M VAD K V E V VTR S ag E D A E AVR WES DGD G EY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 157 T V tld E VN E RIG RGT ILR L F LK D D QL E Y LEE K R IK E V IK RH S E F VAY PI QLVVTK E VEK E V pipeeekkdeekkdeekkd 236
Cdd:COG0326 161 T I --- E EA E KAE RGT EIT L H LK E D AE E F LEE W R LR E I IK KY S D F IPV PI KMEGEE E ETE E D ------------------- 218
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 237 eddkkpkleevdeeeekkpktkkvkeevqei E EL N KTKP LWTR NP S D IT Q EEY NA FYK SISN D W EDPL YVK H FS VEG QL E 316
Cdd:COG0326 219 ------------------------------- E TI N SATA LWTR SK S E IT D EEY KE FYK HLFH D F EDPL FWI H LN VEG PF E 267
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 317 FRAI L F IPK R APFDL FE s KKK K NN IKLYV R RVFI T D E AEDL I PE W L S FV K GVVDS E DLPLN L SRE M LQ QNKIM K V IRK N I 396
Cdd:COG0326 268 YTGL L Y IPK K APFDL YD - RDR K GG IKLYV K RVFI M D D AEDL L PE Y L R FV R GVVDS P DLPLN V SRE I LQ EDRQL K K IRK A I 346
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 397 V KK LIEAFNEI A E - D S E QF EKF YSA F SKNI K L G VH ED TQ NR AAL A K LLR YN STK S v DELTS L TD YV T RM P E H QK N IYYIT 475
Cdd:COG0326 347 T KK VLDELEKL A K n D R E KY EKF WKE F GLVL K E G AL ED FK NR EKI A D LLR FE STK E - GGYVT L AE YV E RM K E G QK K IYYIT 425
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 476 GES LK A V E K SP F L DAL KAK NF EVL F LTDPIDE YAFTQ L K EF E GK TLVDITK - D FE L EE t D EEK A E R E K E IK E YE PL TKAL 554
Cdd:COG0326 426 GES RE A A E Q SP H L EIF KAK GI EVL L LTDPIDE FLISH L E EF D GK KFKSVDS g D LD L DK - L EEK K E S E E E EE E FK PL LERF 504
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 555 KE I LGD Q V EK V V VS YK L L D A PA AIRTGQFGW S AN ME RIM KA QA lrdssm SSYMSS K KTF EI S P KS P II K E L KKRV DE gga 634
Cdd:COG0326 505 KE A LGD K V KD V R VS AR L T D S PA CLVADEGDM S RR ME KML KA MG ------ QDMPEA K PIL EI N P NH P LV K K L AAEE DE --- 575
650 660 670 680
....*....|....*....|....*....|....*....|...
gi 6325016 635 qd KTV KDL TK LLY ET ALL TS G FS L DE P TS F AS R I N R L ISLG L N 677
Cdd:COG0326 576 -- ELF KDL AE LLY DQ ALL AE G GL L ED P AA F VK R L N K L LEKA L G 616
PTZ00130
PTZ00130 heat shock protein 90; Provisional
4-709
1.98e-158
heat shock protein 90; Provisional
Pssm-ID: 185466 [Multi-domain]
Cd Length: 814
Bit Score: 478.00
E-value: 1.98e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 4 E TFEF Q A E I T Q LM SL I I N TV Y SN KE I FLRELISNA S DAL D KIR YK SLSD PKQ L ET E PD L F IRI TPKP E QKV L E I R D S GIG 83
Cdd:PTZ00130 66 E QHQY Q T E V T R LM DI I V N SL Y TQ KE V FLRELISNA A DAL E KIR FL SLSD ESV L GE E KK L E IRI SANK E KNI L S I T D T GIG 145
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 84 MTK AE LINNLGTIAKSGT KA F M EA L S - A G A D V S M IGQFGVGFYS L FLVAD R V Q V IS K S N D DEQYIWES N A GGS FT VTL D E 162
Cdd:PTZ00130 146 MTK ED LINNLGTIAKSGT SN F L EA I S k S G G D M S L IGQFGVGFYS A FLVAD K V I V YT K N N N DEQYIWES T A DAK FT IYK D P 225
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 163 VNERIG RGT ILR L F LK D D QLEYLEE K RIKEV I KRH S E F VA YPI Q L VVTKEVEK EV PIPEEEKKDEEKKDEEK K D E DDKK P 242
Cdd:PTZ00130 226 RGSTLK RGT RIS L H LK E D ATNLMND K KLVDL I SKY S Q F IQ YPI Y L LHENVYTE EV LADIAKEMENDPNYDSV K V E ETDD P 305
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 243 kleevdeeeek KP KT KK V KEE V QEIEEL N KT KP L W T R N P SDI T Q E E Y NA F YKSI S NDWED PLY VK HF SV EG QL EF RAILF 322
Cdd:PTZ00130 306 ----------- NK KT RT V EKK V KKWKLM N EQ KP I W L R P P KEL T D E D Y KK F FSVL S GFNDE PLY HI HF FA EG EI EF KCLIY 374
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 323 IP K RAP FDLFESKK K K N N IKLYVRRV FIT DE AEDLI P EWL SFVKGVVDS E DLPLN L SRE M LQQNKI M K VIR K N IV K K LIE 402
Cdd:PTZ00130 375 IP S RAP SINDHLFT K Q N S IKLYVRRV LVA DE FVEFL P RYM SFVKGVVDS D DLPLN V SRE Q LQQNKI L K AVS K R IV R K ILD 454
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 403 A F N --------------- E I A EDSEQFE K --------------- F Y SAFS K NI K L G VH ED TQ NR AALA KLL RYNSTKSVD 452
Cdd:PTZ00130 455 T F R tlykegkknketlra E L A KETDEEK K keiqkkinepstykl I Y KEYR K YL K T G CY ED DI NR NKIV KLL LFKTMLHPK 534
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 453 EL t SL TD Y VTR M PEH QK N IYY IT G E S LKAVE K S P F L DAL K A KN FE V L FLT DPI DE YAFTQLK E FE GK TLVD I T K - DFEL E 531
Cdd:PTZ00130 535 SI - SL DT Y IEN M KPD QK F IYY AS G D S YEYLS K I P Q L QIF K K KN ID V V FLT ESV DE SCVQRVQ E YD GK KFKS I Q K g EITF E 613
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 532 E T DE EK AER EK EI K E Y EP L TKALKEI L GD Q VE KV VV S YK L L DAP A A IRTGQF G W S AN ME RI MK AQ a LRD S SMSSY MS SK K 611
Cdd:PTZ00130 614 L T ED EK KKE EK VK K M Y KA L IDVISDT L RN Q IF KV EI S RR L V DAP C A VVSTEW G L S GQ ME KL MK IN - VNN S DQIKA MS GQ K 692
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 612 TF EI S P KS PI IKE L K KR v DEGGAQ D KTVKDLT K LL Y ET A L L T SGF S L DEPTSF A S ---- R IN RLISLGL N IDE D E ----- 682
Cdd:PTZ00130 693 IL EI N P DH PI MID L L KR - SVSNPK D SQLTESI K II Y QS A K L A SGF D L EDTADL A Q ivyd H IN QKLGVDN N LKI D D ldpai 771
730 740 750
....*....|....*....|....*....|...
gi 6325016 683 ------ E T E TA P EASTAA pv EE VPA D T E MEEV D 709
Cdd:PTZ00130 772 fetkki E Q E DS P DGQKFH -- EE INI D D E IQKQ D 802
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
14-201
2.13e-103
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 313.69
E-value: 2.13e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 14 QL MS LII NTV YSNKEIFLRELISNASDALDK I RY K SL S DP KQ L ETE P D L F IRI T P KP E QKV L E I R D S GIGMTK A ELINNL 93
Cdd:cd16927 2 QL LD LII HSL YSNKEIFLRELISNASDALDK L RY L SL T DP SL L DDD P E L E IRI S P DK E NRT L T I S D T GIGMTK E ELINNL 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 94 GTIA K SGTKAF M EAL SA GA - D VSM IGQFGVGFYS L F L VAD R V Q V IS KS N - DDE Q Y I WES NA GGS F T VT ld E VNERI GRGT 171
Cdd:cd16927 82 GTIA R SGTKAF L EAL QE GA k D SDL IGQFGVGFYS A F M VAD K V T V TT KS A g DDE G Y R WES DG GGS Y T IE -- E AEGEL GRGT 159
170 180 190
....*....|....*....|....*....|
gi 6325016 172 ILR L F LK D D QL E Y LEE K RIKE VI K RH S E F V 201
Cdd:cd16927 160 KIT L H LK E D AK E F LEE A RIKE LV K KY S D F I 189
PRK14083
PRK14083 HSP90 family protein; Provisional
8-459
2.74e-34
HSP90 family protein; Provisional
Pssm-ID: 237603 [Multi-domain]
Cd Length: 601
Bit Score: 138.54
E-value: 2.74e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 8 FQ AEITQLMS L IINTV YS NKEIFL REL IS NA S DA ldk I RYKSLS DP kql ETEPD lf IRI TP - KPEQKV L EIR D S GIG M T K 86
Cdd:PRK14083 5 FQ VDLRGVID L LSRHL YS SPRVYV REL LQ NA V DA --- I TARRAL DP --- TAPGR -- IRI EL t DAGGGT L IVE D N GIG L T E 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 87 A E LINN L G TI AK S GTKA fm E A L SAGAD v SMI GQFG V G FY S L FLVAD RVQ V I S K S ND D EQYI - W ESN A G G SFT V TLD E V n E 165
Cdd:PRK14083 77 E E VHEF L A TI GR S SKRD -- E N L GFARN - DFL GQFG I G LL S C FLVAD EIV V V S R S AK D GPAV e W RGK A D G TYS V RKL E T - E 152
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 166 R IGR GT ILR L FLKD D QL E Y LE EKRIK E VI K RHSEFVAY PI QLVVT K evekevpipeeekkdeekkdeekkdeddkkpkle 245
Cdd:PRK14083 153 R AEP GT TVY L RPRP D AE E W LE RETVE E LA K KYGSLLPV PI RVEGE K ---------------------------------- 198
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 246 evdeeeekkpktkkvkeevqei EEL N K T K P L WTR NPS D ITQEE ----------- YNAFYKS I sndwed PL Y V KHFSV EG q 314
Cdd:PRK14083 199 ---------------------- GGV N E T P P P WTR DYP D PETRR eallaygeell GFTPLDV I ------ PL D V PSGGL EG - 249
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 315 lefra ILFI - P KRAPF dlfe SKKK K N ni KL Y VR R VFITD EAE D L I P E W LS FV KG VV DSED L PLNL SRE M L QQNKIMKVI R 393
Cdd:PRK14083 250 ----- VAYV l P YAVSP ---- AARR K H -- RV Y LK R MLLSE EAE N L L P D W AF FV RC VV NTDE L RPTA SRE A L YEDDALAAV R 318
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 394 KNIVKKLIEAFNEI A E - D S E QFEKFYSAFSKNI K - L GV H E D -------------- T QN R AA LA KLL R YNS ---- T K SVDE 453
Cdd:PRK14083 319 EELGEAIRKWLIGL A T t D P E RLRRLLAVHHLGV K a L AS H D D ellrlilpwlpfet T DG R MT LA EIR R RHG viry T S SVDE 398
....*.
gi 6325016 454 LTS L TD 459
Cdd:PRK14083 399 FRQ L AP 404
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
26-161
1.05e-09
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 56.50
E-value: 1.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 26 NKEIF LR ELI SN AS D AL dk I R Y K slsdpkql ETEPDLFIRITPKPEQKVLEIR D S G I G MTKAE L innlgtiaksg T K A F M 105
Cdd:smart00387 1 GDPDR LR QVL SN LL D NA -- I K Y T -------- PEGGRITVTLERDGDHVEITVE D N G P G IPPED L ----------- E K I F E 59
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 6325016 106 EALSAGADVSM IG QF G V G FYSLFLVADRVQV - IS KSNDDEQ yiwesna G GS FT V TL D 161
Cdd:smart00387 60 PFFRTDKRSRK IG GT G L G LSIVKKLVELHGG e IS VESEPGG ------- G TT FT I TL P 109
HATPase_c
pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ...
26-181
5.93e-06
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain]
Cd Length: 109
Bit Score: 45.44
E-value: 5.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325016 26 NK E IF LR ELI SN AS D ALD K IRY K slsdpkqlet EPDLFIRITPK p EQKV L EIR D S GIG MTK a E LINNLGT iaksgtk A F M 105
Cdd:pfam02518 1 GD E LR LR QVL SN LL D NAL K HAA K ---------- AGEITVTLSEG - GELT L TVE D N GIG IPP - E DLPRIFE ------- P F S 61
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6325016 106 E alsag AD VSMI G QF G V G FY slflvadrvqv I SKS nddeqy IW E S n A GG SF TV T ldevn ERI G R GT ILR L F L KDD Q 181
Cdd:pfam02518 62 T ----- AD KRGG G GT G L G LS ----------- I VRK ------ LV E L - L GG TI TV E ----- SEP G G GT TVT L T L PLA Q 109
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
