|
Name |
Accession |
Description |
Interval |
E-value |
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
133-338 |
1.94e-103 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 313.74 E-value: 1.94e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 133 FSKVCVNEEGIQKLQRAVQE-HPVVLLPSHRSYIDFLMLSFILYSYDLPVPVIAAGMDFLGMrVVSELLRMSGAFFMRRT 211
Cdd:cd07993 1 FDGVQVNEGQLERLRKAAQEgHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIP-ILGTLLRRLGAFFIRRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 212 FGGNKLYWAVFSEYVKTMLRCGYaPVEFFLEGTRSRAAKTLTPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEESL 291
Cdd:cd07993 80 FGKDPLYRAVLQEYVQELLKNGQ-PLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVLEEEL 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 160298207 292 YAYEILGVPKPKESTTGLLKARRILSENFGSIHVYFGDPVSLRSLAA 338
Cdd:cd07993 159 YAEELLGPPKPKESLSGLLGASKILRENFGRIRVDFGEPISLREYLG 205
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
74-642 |
4.67e-103 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 329.58 E-value: 4.67e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 74 VLSSEEINYVIKQLSRESLTGVDVLREEASEILEEMSHKLRIGAIRFFAFVLSKIFKQIFSKVCVNeeGIQKLQRAVQEH 153
Cdd:COG2937 126 LLRSPAVRKAIEEEAKSKGISEEKARKEARRYLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRVD--NLERLRELAKGH 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 154 PVVLLPSHRSYIDFLMLSFILYSYDLPVPVIAAGmDFLGMRVVSELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRCG 233
Cdd:COG2937 204 EIVYVPCHRSHMDYLLLSYVLYHNGLVPPHIAAG-INLNFWPLGPILRRGGAFFIRRSFKGNKLYSAVFREYLAELFERG 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 234 YaPVEFFLEGTRSRAAKTLTPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEESLYAYEILGVPKPKESTTGLLKAR 313
Cdd:COG2937 283 Y-SVEYFIEGGRSRTGRLLPPKTGMLSMTVQAFLRGARRPVVFVPVYIGYERVLEVGSYAKELRGGEKKKESLGGLLRAL 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 314 RILSENFGSIHVYFGDPVSLRSLAagrlnrNTYNLVPRCIPQKQPEDVQAFVTEVAYK-MQllQIENLA-LSPWLLVVTI 391
Cdd:COG2937 362 RKLRRRFGRVYVNFGEPISLSEYL------DQHVPDWRESEDLRPEWLRPAVDKLAFEiMV--RINRAAaVNPVNLVALA 433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 392 LLQN-QLSMDFDALVEKtlwLKGVTQVFGGFLLWPDNKLPEEVVQssillhSNLASLVKDQVVLKMNSGSSQVVngLVPE 470
Cdd:COG2937 434 LLASpKRALTEAELLAQ---LDLYLDLLRNVPYSLSVTLPELTPE------ELLEHLLSLGLIEVEKDGLGDVI--SIDD 502
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 471 HIALLMcSAYRNQLLNIFARPSLVALALHMTPGLRKEDVFSCFSFLRNVFSDEFIFLPGNTLRD-FEEGCYLLCKAEAMQ 549
Cdd:COG2937 503 EQAVLL-TYYRNNILHLFALPALIASALLANRRISRAELLELVRLLYPLLKAELFLRWDAEFEEvLDEELDELVRQGLLE 581
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 550 MAGKDIILTDKGTAVLQFLTSLFKPFVESYQLLCRYLLHE-EDYFGEKEYLVAARKFTRQLLDQGSSQCYDALSSELQKN 628
Cdd:COG2937 582 REGDTLRRPPARFRQLQLLAHVLRETLERYAIVLSLLAKLgSGTLDRKELEKESLLLAQRLSLLHGINAPEFFDKALFRN 661
|
570
....*....|....
gi 160298207 629 ALAAFVRLGVVEKK 642
Cdd:COG2937 662 FIQTLREQGYLDDD 675
|
|
| PTZ00374 |
PTZ00374 |
dihydroxyacetone phosphate acyltransferase; Provisional |
41-524 |
4.80e-76 |
|
dihydroxyacetone phosphate acyltransferase; Provisional
Pssm-ID: 240389 [Multi-domain] Cd Length: 1108 Bit Score: 264.43 E-value: 4.80e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 41 RRHISDFKFAMKC-YTPPLYRG-ITPCKPGDIKSIVLSSEEINYVIKQLS-RESLTGVDVlREEASEILEEMSHKLRIGA 117
Cdd:PTZ00374 513 RKYFDDVVWTQRVgLTANGWRFaATPGLTPESLTSILAQPSIQRLMTALAkKEGASEKDV-EARAKAILRTCGDNLNHVQ 591
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 118 IRFFAFVLSKIFKQIFSKVCVNEEGIQKLQRAVQEhP---VVLLPSHRSYIDFLMLSFILYSYDLPVPVIAAGMDFLGMR 194
Cdd:PTZ00374 592 CRLFGLMVRRILFRLYDRVSLNSGAFERLHRYVAM-PrvaVVLLPLHRSYIDFIIMTYLLAVMGLPLPHVCAGDDFLRMG 670
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 195 VVSELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRcGYAPVEFFLEGTRSRAAKTLTPKFGLLNIVMEPFF--KREVF 272
Cdd:PTZ00374 671 PIATLMRGSGAFFMRRSFRDDPLYAALFKEYVRHLVL-RRRPLEFFIEGTRSRTGKTMAPKLGLLKFICDTFYegQQELD 749
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 273 DTYFVPISISYDKILEESLYAYEILGVPKPKESTTGLLKARRILSENFGSIHVYFGDPVSLRSL---------------- 336
Cdd:PTZ00374 750 DVLIIPVSLSYDELLETTLYAKEQLGVSKPKENPGNLLRARSLLKRRHGKIHVHIGEPVSLRSFkdhplqcplpfepkge 829
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 337 --AAGRLNRNTYNLVPRCiPQKQPEDVQAFVT-EVAYKMQllqiENLALSPWLLVVTILlqNQLS-----MDFDALVEKT 408
Cdd:PTZ00374 830 atTSVCKTLDTTPSIARK-SSITPPRVLTNIAwHLTHKLQ----RNTIITPTALVAAVL--ECLGptagaMPLAEVQQGM 902
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 409 LWLKGVTQVFGGFLLWPDNKL-PEEVVQSSIllhSNLASLVkdQVVLKMnsGSSQVVNGLVPEHIALLMCSayrNQLLNI 487
Cdd:PTZ00374 903 TWLRTNIRRRGAALSDDCANLnPETMVRKAL---THLQEFV--EITDEM--SEVIYVRQDVVTRLGVNICS---NQLIHV 972
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 160298207 488 FARPSLVALALHM-----TPG--LR-KEDVFS--CfSFLRNVFSDEF 524
Cdd:PTZ00374 973 FMDEAVVAVVARAfgevtAPHrvRRvEADVLKeqC-QLLRQLLSAEF 1018
|
|
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
74-495 |
7.40e-62 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 220.87 E-value: 7.40e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 74 VLSSEEINYVIKQLSRESLTGVDVLREEASEILEEMSHKLRIGAIRFFAFVLSKIFKQIFSKVCV-NEEGIQKLqrAVQE 152
Cdd:PRK04974 224 LLASPAIKKAIEDEAKSKKISHEKARQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVhNAERVRQL--AQDG 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 153 HPVVLLPSHRSYIDFLMLSFILYSYDLPVPVIAAGMDfLGMRVVSELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRC 232
Cdd:PRK04974 302 HEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN-LNFWPAGPIFRRGGAFFIRRSFKGNKLYSTVFREYLGELFAR 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 233 GYaPVEFFLEGTRSRAAKTLTPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEESLYAYEILGVPKPKESTTGLLKA 312
Cdd:PRK04974 381 GY-SVEYFVEGGRSRTGRLLQPKTGMLAMTLQAMLRGSRRPITLVPVYIGYEHVMEVGTYAKELRGAPKEKESLFQVLRG 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 313 RRILSeNFGSIHVYFGDPVSLrslaAGRLNRN--TYNLVPRCIPQKQPEDVQAFVTEVAYKMQllqiENL----ALSPWL 386
Cdd:PRK04974 460 IRKLR-NFGQGYVNFGEPIPL----NDYLNQHvpEWRESIDPIEEQRPAWLTPAVNNLANQVM----VRInnaaAANPVN 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 387 LVVTILLQN-QLSMDFDALVEK-TLWLKGVTQV-FGGFLLWPDNKlPEEVVQSSILLhsNLASLVKDqvvlkmNSGSsqV 463
Cdd:PRK04974 531 LCALALLASrQRALDREQLIEQlDLYLQLLRNVpYSSDTTVPEGS-GEELIDHALSL--NKFEVEKD------TLGD--I 599
|
410 420 430
....*....|....*....|....*....|..
gi 160298207 464 VNglVPEHIALLMcSAYRNQLLNIFARPSLVA 495
Cdd:PRK04974 600 IS--LDREQAVLM-TYYRNNILHLFVLPSLIA 628
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
137-282 |
1.39e-28 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 110.83 E-value: 1.39e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 137 CVNEEGIQKLQRavqEHPVVLLPSHRSYIDFLMLSFILYSYDLPvPVIAAGMDFLGMRVVSELLRMSGAFFMRRtfgGNK 216
Cdd:pfam01553 1 RIEVHGLENLPR---GGPAIVVANHQSYLDVLLLSLALYKRGRP-LVFVAKKELFDIPLVGWLMRLLGCIFIDR---KNR 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 160298207 217 LYWAVFSEYVKTMLRCGYaPVEFFLEGTRSRAAKTLTPKFGLLNIVMEpffkrevFDTYFVPISIS 282
Cdd:pfam01553 74 KDAAGTLEYLVELLREGK-LVVIFPEGTRSREGELLPFKKGAFRLAIE-------AGVPIVPVAIS 131
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
155-284 |
1.22e-19 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 84.71 E-value: 1.22e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 155 VVLLPSHRSYIDFLMLSFILYSYDLPVPVIAAGMDFLgMRVVSELLRMSGAFFMRRTFGgnKLYWAVFSEYVKtMLRCGY 234
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFY-VPLLGWLLRLLGAIFIDRSNG--RKARAALREAVE-LLKEGE 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 160298207 235 aPVEFFLEGTRSRAAKTLTPKFGLLNIVMEPffkrevfDTYFVPISISYD 284
Cdd:smart00563 77 -WLLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRGT 118
|
|
| GPAT_C |
pfam19277 |
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal ... |
292-643 |
2.46e-17 |
|
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal region of Glycerol-3-phosphate acyltransferase.
Pssm-ID: 466024 Cd Length: 370 Bit Score: 84.11 E-value: 2.46e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 292 YAYEILGVPKPKESTTGLLK-ARRILSENFGSIHVYFGDPVSLRSLaagrlnrntynLVPRCIPQKQPEDVQ-AFVTEVA 369
Cdd:pfam19277 1 YAAELLGGPKKPEGLSWLLSyARSQLSLKLGRVYVRFGEPWSLREF-----------LDEQGDRPATDAARRrLALQKLA 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 370 YKMqLLQIeNLA--LSPWLLVVTILL--------QNQLSMDFDALVEktlWL--KGVTQvfGGFLLWPDnklpEEVVQSS 437
Cdd:pfam19277 70 FEV-LSRI-NRVtpVMPTALVGTVLLtlrgraltLSELIRRVEWLLD---YIraRGGPV--AHFGDLRT----EEVVDRA 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 438 illhsnLASLVKDQVVLKMNSGsSQVVNGLVPE--HIAllmcSAYRNQLLNIFARPSLVALALHMTP-----GLRKEDVF 510
Cdd:pfam19277 139 ------LDVLGNAGLVTRVDGG-PEPVYYIAPEdhFQA----SFYRNMTIHLFVERAIVELALLTKVkaaqrGDSYEALW 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 511 SCFSFLRNVFSDEFIFLPGNTLR-DFEEGCYLLCKAEAMQMAGKDIILTDKGTAVLQFLTSLFKPFVESYQLLCRYLLHE 589
Cdd:pfam19277 208 DQVLRLRDLLKFEFFFPPKEGFReNLRAELDLLDPWEDRVITGERDIERLLGRENPDFACFLLWPFIEAYWLVADSLADL 287
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 160298207 590 EDY--FGEKEYLVAARKFTRQLLDQGSSQCYDALSSELQKNALAAFVRLGVVEKKK 643
Cdd:pfam19277 288 TPDawIDEKDFQDEALGLGKQLYLQGRLSSFESVSKELFKNALQLAENRGLLEVSR 343
|
|
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
113-337 |
4.40e-08 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 54.25 E-value: 4.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 113 LRIGAIRFFAFVLSKIFKQIFSKVCVneEGIQKLQRavqEHPVVLLPSHRSYIDFLMLSFIlysydLPVPV-IAAGMDFL 191
Cdd:COG0204 8 LRRFRYRLVRLWARLLLRLLGVRVRV--EGLENLPA---DGPVLIVANHQSWLDILLLLAA-----LPRPVrFVAKKELF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 192 GMRVVSELLRMSGAFFMRRTFGGNKLywAVFsEYVKTMLRCGYAPVeFFLEGTRSRAAKTLTPKFGLLNIVMEpffkrev 271
Cdd:COG0204 78 KIPLLGWLLRALGAIPVDRSKRRAAL--RAL-RQAVEALKAGESLV-IFPEGTRSPDGRLLPFKTGAARLALE------- 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 160298207 272 FDTYFVPISISYdkileeSLYAYEILGVPKPkesttgllkarrilsenfGSIHVYFGDPVSLRSLA 337
Cdd:COG0204 147 AGVPIVPVAIDG------TERALPKGFLPRP------------------GKVTVRIGPPIDPSDLE 188
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
133-338 |
1.94e-103 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 313.74 E-value: 1.94e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 133 FSKVCVNEEGIQKLQRAVQE-HPVVLLPSHRSYIDFLMLSFILYSYDLPVPVIAAGMDFLGMrVVSELLRMSGAFFMRRT 211
Cdd:cd07993 1 FDGVQVNEGQLERLRKAAQEgHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIP-ILGTLLRRLGAFFIRRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 212 FGGNKLYWAVFSEYVKTMLRCGYaPVEFFLEGTRSRAAKTLTPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEESL 291
Cdd:cd07993 80 FGKDPLYRAVLQEYVQELLKNGQ-PLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVLEEEL 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 160298207 292 YAYEILGVPKPKESTTGLLKARRILSENFGSIHVYFGDPVSLRSLAA 338
Cdd:cd07993 159 YAEELLGPPKPKESLSGLLGASKILRENFGRIRVDFGEPISLREYLG 205
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
74-642 |
4.67e-103 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 329.58 E-value: 4.67e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 74 VLSSEEINYVIKQLSRESLTGVDVLREEASEILEEMSHKLRIGAIRFFAFVLSKIFKQIFSKVCVNeeGIQKLQRAVQEH 153
Cdd:COG2937 126 LLRSPAVRKAIEEEAKSKGISEEKARKEARRYLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRVD--NLERLRELAKGH 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 154 PVVLLPSHRSYIDFLMLSFILYSYDLPVPVIAAGmDFLGMRVVSELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRCG 233
Cdd:COG2937 204 EIVYVPCHRSHMDYLLLSYVLYHNGLVPPHIAAG-INLNFWPLGPILRRGGAFFIRRSFKGNKLYSAVFREYLAELFERG 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 234 YaPVEFFLEGTRSRAAKTLTPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEESLYAYEILGVPKPKESTTGLLKAR 313
Cdd:COG2937 283 Y-SVEYFIEGGRSRTGRLLPPKTGMLSMTVQAFLRGARRPVVFVPVYIGYERVLEVGSYAKELRGGEKKKESLGGLLRAL 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 314 RILSENFGSIHVYFGDPVSLRSLAagrlnrNTYNLVPRCIPQKQPEDVQAFVTEVAYK-MQllQIENLA-LSPWLLVVTI 391
Cdd:COG2937 362 RKLRRRFGRVYVNFGEPISLSEYL------DQHVPDWRESEDLRPEWLRPAVDKLAFEiMV--RINRAAaVNPVNLVALA 433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 392 LLQN-QLSMDFDALVEKtlwLKGVTQVFGGFLLWPDNKLPEEVVQssillhSNLASLVKDQVVLKMNSGSSQVVngLVPE 470
Cdd:COG2937 434 LLASpKRALTEAELLAQ---LDLYLDLLRNVPYSLSVTLPELTPE------ELLEHLLSLGLIEVEKDGLGDVI--SIDD 502
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 471 HIALLMcSAYRNQLLNIFARPSLVALALHMTPGLRKEDVFSCFSFLRNVFSDEFIFLPGNTLRD-FEEGCYLLCKAEAMQ 549
Cdd:COG2937 503 EQAVLL-TYYRNNILHLFALPALIASALLANRRISRAELLELVRLLYPLLKAELFLRWDAEFEEvLDEELDELVRQGLLE 581
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 550 MAGKDIILTDKGTAVLQFLTSLFKPFVESYQLLCRYLLHE-EDYFGEKEYLVAARKFTRQLLDQGSSQCYDALSSELQKN 628
Cdd:COG2937 582 REGDTLRRPPARFRQLQLLAHVLRETLERYAIVLSLLAKLgSGTLDRKELEKESLLLAQRLSLLHGINAPEFFDKALFRN 661
|
570
....*....|....
gi 160298207 629 ALAAFVRLGVVEKK 642
Cdd:COG2937 662 FIQTLREQGYLDDD 675
|
|
| PTZ00374 |
PTZ00374 |
dihydroxyacetone phosphate acyltransferase; Provisional |
41-524 |
4.80e-76 |
|
dihydroxyacetone phosphate acyltransferase; Provisional
Pssm-ID: 240389 [Multi-domain] Cd Length: 1108 Bit Score: 264.43 E-value: 4.80e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 41 RRHISDFKFAMKC-YTPPLYRG-ITPCKPGDIKSIVLSSEEINYVIKQLS-RESLTGVDVlREEASEILEEMSHKLRIGA 117
Cdd:PTZ00374 513 RKYFDDVVWTQRVgLTANGWRFaATPGLTPESLTSILAQPSIQRLMTALAkKEGASEKDV-EARAKAILRTCGDNLNHVQ 591
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 118 IRFFAFVLSKIFKQIFSKVCVNEEGIQKLQRAVQEhP---VVLLPSHRSYIDFLMLSFILYSYDLPVPVIAAGMDFLGMR 194
Cdd:PTZ00374 592 CRLFGLMVRRILFRLYDRVSLNSGAFERLHRYVAM-PrvaVVLLPLHRSYIDFIIMTYLLAVMGLPLPHVCAGDDFLRMG 670
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 195 VVSELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRcGYAPVEFFLEGTRSRAAKTLTPKFGLLNIVMEPFF--KREVF 272
Cdd:PTZ00374 671 PIATLMRGSGAFFMRRSFRDDPLYAALFKEYVRHLVL-RRRPLEFFIEGTRSRTGKTMAPKLGLLKFICDTFYegQQELD 749
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 273 DTYFVPISISYDKILEESLYAYEILGVPKPKESTTGLLKARRILSENFGSIHVYFGDPVSLRSL---------------- 336
Cdd:PTZ00374 750 DVLIIPVSLSYDELLETTLYAKEQLGVSKPKENPGNLLRARSLLKRRHGKIHVHIGEPVSLRSFkdhplqcplpfepkge 829
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 337 --AAGRLNRNTYNLVPRCiPQKQPEDVQAFVT-EVAYKMQllqiENLALSPWLLVVTILlqNQLS-----MDFDALVEKT 408
Cdd:PTZ00374 830 atTSVCKTLDTTPSIARK-SSITPPRVLTNIAwHLTHKLQ----RNTIITPTALVAAVL--ECLGptagaMPLAEVQQGM 902
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 409 LWLKGVTQVFGGFLLWPDNKL-PEEVVQSSIllhSNLASLVkdQVVLKMnsGSSQVVNGLVPEHIALLMCSayrNQLLNI 487
Cdd:PTZ00374 903 TWLRTNIRRRGAALSDDCANLnPETMVRKAL---THLQEFV--EITDEM--SEVIYVRQDVVTRLGVNICS---NQLIHV 972
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 160298207 488 FARPSLVALALHM-----TPG--LR-KEDVFS--CfSFLRNVFSDEF 524
Cdd:PTZ00374 973 FMDEAVVAVVARAfgevtAPHrvRRvEADVLKeqC-QLLRQLLSAEF 1018
|
|
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
74-495 |
7.40e-62 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 220.87 E-value: 7.40e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 74 VLSSEEINYVIKQLSRESLTGVDVLREEASEILEEMSHKLRIGAIRFFAFVLSKIFKQIFSKVCV-NEEGIQKLqrAVQE 152
Cdd:PRK04974 224 LLASPAIKKAIEDEAKSKKISHEKARQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVhNAERVRQL--AQDG 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 153 HPVVLLPSHRSYIDFLMLSFILYSYDLPVPVIAAGMDfLGMRVVSELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRC 232
Cdd:PRK04974 302 HEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN-LNFWPAGPIFRRGGAFFIRRSFKGNKLYSTVFREYLGELFAR 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 233 GYaPVEFFLEGTRSRAAKTLTPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEESLYAYEILGVPKPKESTTGLLKA 312
Cdd:PRK04974 381 GY-SVEYFVEGGRSRTGRLLQPKTGMLAMTLQAMLRGSRRPITLVPVYIGYEHVMEVGTYAKELRGAPKEKESLFQVLRG 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 313 RRILSeNFGSIHVYFGDPVSLrslaAGRLNRN--TYNLVPRCIPQKQPEDVQAFVTEVAYKMQllqiENL----ALSPWL 386
Cdd:PRK04974 460 IRKLR-NFGQGYVNFGEPIPL----NDYLNQHvpEWRESIDPIEEQRPAWLTPAVNNLANQVM----VRInnaaAANPVN 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 387 LVVTILLQN-QLSMDFDALVEK-TLWLKGVTQV-FGGFLLWPDNKlPEEVVQSSILLhsNLASLVKDqvvlkmNSGSsqV 463
Cdd:PRK04974 531 LCALALLASrQRALDREQLIEQlDLYLQLLRNVpYSSDTTVPEGS-GEELIDHALSL--NKFEVEKD------TLGD--I 599
|
410 420 430
....*....|....*....|....*....|..
gi 160298207 464 VNglVPEHIALLMcSAYRNQLLNIFARPSLVA 495
Cdd:PRK04974 600 IS--LDREQAVLM-TYYRNNILHLFVLPSLIA 628
|
|
| PRK03355 |
PRK03355 |
glycerol-3-phosphate 1-O-acyltransferase; |
95-630 |
2.81e-48 |
|
glycerol-3-phosphate 1-O-acyltransferase;
Pssm-ID: 179567 [Multi-domain] Cd Length: 783 Bit Score: 181.83 E-value: 2.81e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 95 VDVLREEASEILEEMSHKLRIGAIRFFAfVLSKIFKQIFS-KVCVNEEGIQKLQRAVQEHPVVLLPSHRSYIDFLMLSFI 173
Cdd:PRK03355 209 PGATVREAGKMLDELVAGWSRVSVDLVS-VLGRLFSRGFDpEIDYDEYELAALRALLEEHPAVLLFSHRSYIDGLVVPVA 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 174 LYSYDLPVPVIAAGMDfLGMRVVSELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRCGYaPVEFFLEGTRSRAAKTLT 253
Cdd:PRK03355 288 MQENRLPPVHVFGGIN-LSFGPMGPIMRRSGMIFIRRNIGDDPLYKYVLREYVGYLVEKRF-NLSWYIEGTRSRTGKLLP 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 254 PKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEESLYAYEILGVPKPKESTTGLLKARRILSE-NFGSIHVYFGDPVS 332
Cdd:PRK03355 366 PKLGLLSYVADAYLDGRSDDVLLQPVSISFDQLHEIGEYAAEARGGEKTPEGLRWLYNYIKAQGErNYGKIYVRFGEPVS 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 333 LRSlaagRLNRNTYNLVPRciPQKQPEDVQAFVTEVAYKmqLLQIENLALSPwllVVTILLqnqLSMDFDALVEKTLwlk 412
Cdd:PRK03355 446 MRQ----YLGAPHGPLTQD--PDAKRLALQKMAFEVAWR--INQVTPVTATS---LVSLLL---LGTRGRALTLDEL--- 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 413 gvTQVFGGFLLWPDNK-LP----------EEVVQSSILLHSNlaslvkDQVVLKMNSGSSQVVNgLVPEHiaLLMCSAYR 481
Cdd:PRK03355 509 --HHTLQDSLDYLERRqLPvstsalrlrdPEGVRAALDALSN------GGPVTRVDSGREPVWY-IAPDD--HLVAAFYR 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 482 NQLLNIFARPSLVALALHMTPGLRKEDVFSCF----SFLRNVFSDEFIFLPGNTLRD--FEEGCYLLCKAEAMQMAGkdi 555
Cdd:PRK03355 578 NSVIHAFLERAIVELALAAAAHVDEGDRLAAFwdqaMRLRDLLKFEFFFADSDAFRAnlRAEMAWIDPDWEDRLAAG--- 654
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 556 iltDKGTAVL----QFLTS--LFKPFVESYQLLCRYLLHEE-DYFGEKEYLVAARKFTRQLLDQGSSQCYDALSSELQKN 628
Cdd:PRK03355 655 ---GDEIDALlrakRPLMAhaMLRPFFEAYEVVADVLRDAPpDTIDEKELTALALGLGRQYVLQGRVRSSESVSTLLFAT 731
|
..
gi 160298207 629 AL 630
Cdd:PRK03355 732 AR 733
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
137-282 |
1.39e-28 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 110.83 E-value: 1.39e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 137 CVNEEGIQKLQRavqEHPVVLLPSHRSYIDFLMLSFILYSYDLPvPVIAAGMDFLGMRVVSELLRMSGAFFMRRtfgGNK 216
Cdd:pfam01553 1 RIEVHGLENLPR---GGPAIVVANHQSYLDVLLLSLALYKRGRP-LVFVAKKELFDIPLVGWLMRLLGCIFIDR---KNR 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 160298207 217 LYWAVFSEYVKTMLRCGYaPVEFFLEGTRSRAAKTLTPKFGLLNIVMEpffkrevFDTYFVPISIS 282
Cdd:pfam01553 74 KDAAGTLEYLVELLREGK-LVVIFPEGTRSREGELLPFKKGAFRLAIE-------AGVPIVPVAIS 131
|
|
| LPLAT |
cd06551 |
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ... |
133-347 |
2.06e-24 |
|
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).
Pssm-ID: 153244 [Multi-domain] Cd Length: 187 Bit Score: 100.95 E-value: 2.06e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 133 FSKVCVNEEGIQKLQRAVQEH-----PVVLLPSHRSYIDFLMLSFILYsYDLPVPVIAAGMDFLGMRVvsELLRMSGAFF 207
Cdd:cd06551 1 FRYLLLNFFGFVRLEVKGPPPppgggPVLFVSNHSSWWDGLILFLLLE-RGLRRDVYGLMDEELLERY--PFFTRLGAFS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 208 MRRTFGGnklYWAVFSEYVKTMLRCGYAPVEFFLEGTRSRAAK-TLTPKFGLLNIvmepffkREVFDTYFVPISISYDKI 286
Cdd:cd06551 78 VDRDSPR---SAAKSLKYVARLLSKPGSVVWIFPEGTRTRRDKrPLQFKPGVAHL-------AEKAGVPIVPVALRYTFE 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 160298207 287 LEeslyayeilgvpkpkesttgllkarrilsENFGSIHVYFGDPVSLRSLAAGRLNRNTYN 347
Cdd:cd06551 148 LF-----------------------------EQFPEIFVRIGPPIPYAETALGEELAAELA 179
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
155-284 |
1.22e-19 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 84.71 E-value: 1.22e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 155 VVLLPSHRSYIDFLMLSFILYSYDLPVPVIAAGMDFLgMRVVSELLRMSGAFFMRRTFGgnKLYWAVFSEYVKtMLRCGY 234
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFY-VPLLGWLLRLLGAIFIDRSNG--RKARAALREAVE-LLKEGE 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 160298207 235 aPVEFFLEGTRSRAAKTLTPKFGLLNIVMEPffkrevfDTYFVPISISYD 284
Cdd:smart00563 77 -WLLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRGT 118
|
|
| PRK11915 |
PRK11915 |
lysophospholipid acyltransferase; |
78-630 |
1.73e-17 |
|
lysophospholipid acyltransferase;
Pssm-ID: 237022 [Multi-domain] Cd Length: 621 Bit Score: 86.54 E-value: 1.73e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 78 EEINYVIKQLSRESltgvDVLREEASEILEEM--SHKLR-IGAIRFFAFVLSKIFKqifskVCVNEEGIQKLQRAVQEHP 154
Cdd:PRK11915 46 ERLRALADELGRDP----DSVRAEAAGYLREMaaSLDERaVQAWRGFSRWLMRAYD-----VLVDEDQITQLRKLDRKAT 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 155 VVLLPSHRSYIDFLMLSFILYSYDLpVPVIAAGMDFLGMRVVSELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRcGY 234
Cdd:PRK11915 117 LAFAFSHRSYLDGMLLPEVILANRL-SPALTFGGANLNFFPMGAWAKRTGAIFIRRQTKDIPVYRFVLRAYAAQLVQ-NH 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 235 APVEFFLEGTRSRAAKTLTPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEESLYAYEILGVPKPKESTTGLLKARR 314
Cdd:PRK11915 195 VNLTWSIEGGRTRTGKLRPPVFGILRYITDAVDEIDGPEVYLVPTSIVYDQLHEVEAMTTEAYGAVKRPEDLRFLVRLAR 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 315 ILSENFGSIHVYFGDPVSLRSlaagRLNRntynlvPRCIPQKQPEDVQAFVTEVAYKMqllqieNLA--LSPWLLVVTIL 392
Cdd:PRK11915 275 QQGERLGRAYLDFGEPLPLRK----RLQE------LRADKSGTGSEIERIALDVEHRI------NRAtpVTPTAVVSLAL 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 393 LQNQLSMDFDALVEKTLWLKGVTQVFGgfllWPDNKLPEEVVQSSIllHSNLASLVKDQVVLKMNSGSSQVVNGLVPEHi 472
Cdd:PRK11915 339 LGADRSLSISEVLATVRPLASYIAARN----WAVAGAADLTNRSTI--RWTLHQMVASGVVSVYDAGTEAVWGIGEDQH- 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 473 alLMCSAYRNQLLNIFARPSLVALALHMTPGLRKE------DVFSCFSFLRNVFSDEFIFlPGNTL--RDFEEGCYLLCK 544
Cdd:PRK11915 412 --LVAAFYRNTAIHILVDRAIAELALLAAAETTTNgsvspaTVRDEALSLRELLKFEFLF-SGRAQfeKDLANEVRLIGS 488
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 545 AEAMQMA-GKDIILTDKGTAVLQFLTSLFKPFVESYQLLC-RYLLHEEDYFGEKEYLVAARKFTRQLLDQGSSQCYDALS 622
Cdd:PRK11915 489 VVDTSKAaAAADVWRLLESADLLLAHLVLRPFLDAYHIVAdRLAAHEDDSFDEEGFLAECLQVGKQWELQRRIASAESRS 568
|
....*...
gi 160298207 623 SELQKNAL 630
Cdd:PRK11915 569 MELFKTAL 576
|
|
| GPAT_C |
pfam19277 |
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal ... |
292-643 |
2.46e-17 |
|
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal region of Glycerol-3-phosphate acyltransferase.
Pssm-ID: 466024 Cd Length: 370 Bit Score: 84.11 E-value: 2.46e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 292 YAYEILGVPKPKESTTGLLK-ARRILSENFGSIHVYFGDPVSLRSLaagrlnrntynLVPRCIPQKQPEDVQ-AFVTEVA 369
Cdd:pfam19277 1 YAAELLGGPKKPEGLSWLLSyARSQLSLKLGRVYVRFGEPWSLREF-----------LDEQGDRPATDAARRrLALQKLA 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 370 YKMqLLQIeNLA--LSPWLLVVTILL--------QNQLSMDFDALVEktlWL--KGVTQvfGGFLLWPDnklpEEVVQSS 437
Cdd:pfam19277 70 FEV-LSRI-NRVtpVMPTALVGTVLLtlrgraltLSELIRRVEWLLD---YIraRGGPV--AHFGDLRT----EEVVDRA 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 438 illhsnLASLVKDQVVLKMNSGsSQVVNGLVPE--HIAllmcSAYRNQLLNIFARPSLVALALHMTP-----GLRKEDVF 510
Cdd:pfam19277 139 ------LDVLGNAGLVTRVDGG-PEPVYYIAPEdhFQA----SFYRNMTIHLFVERAIVELALLTKVkaaqrGDSYEALW 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 511 SCFSFLRNVFSDEFIFLPGNTLR-DFEEGCYLLCKAEAMQMAGKDIILTDKGTAVLQFLTSLFKPFVESYQLLCRYLLHE 589
Cdd:pfam19277 208 DQVLRLRDLLKFEFFFPPKEGFReNLRAELDLLDPWEDRVITGERDIERLLGRENPDFACFLLWPFIEAYWLVADSLADL 287
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 160298207 590 EDY--FGEKEYLVAARKFTRQLLDQGSSQCYDALSSELQKNALAAFVRLGVVEKKK 643
Cdd:pfam19277 288 TPDawIDEKDFQDEALGLGKQLYLQGRLSSFESVSKELFKNALQLAENRGLLEVSR 343
|
|
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
113-337 |
4.40e-08 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 54.25 E-value: 4.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 113 LRIGAIRFFAFVLSKIFKQIFSKVCVneEGIQKLQRavqEHPVVLLPSHRSYIDFLMLSFIlysydLPVPV-IAAGMDFL 191
Cdd:COG0204 8 LRRFRYRLVRLWARLLLRLLGVRVRV--EGLENLPA---DGPVLIVANHQSWLDILLLLAA-----LPRPVrFVAKKELF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 192 GMRVVSELLRMSGAFFMRRTFGGNKLywAVFsEYVKTMLRCGYAPVeFFLEGTRSRAAKTLTPKFGLLNIVMEpffkrev 271
Cdd:COG0204 78 KIPLLGWLLRALGAIPVDRSKRRAAL--RAL-RQAVEALKAGESLV-IFPEGTRSPDGRLLPFKTGAARLALE------- 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 160298207 272 FDTYFVPISISYdkileeSLYAYEILGVPKPkesttgllkarrilsenfGSIHVYFGDPVSLRSLA 337
Cdd:COG0204 147 AGVPIVPVAIDG------TERALPKGFLPRP------------------GKVTVRIGPPIDPSDLE 188
|
|
| LPLAT_AGPAT-like |
cd07989 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ... |
154-344 |
1.19e-06 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.
Pssm-ID: 153251 [Multi-domain] Cd Length: 184 Bit Score: 49.19 E-value: 1.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 154 PVVLLPSHRSYIDFLMLSFILYSYdlPVPVIAAgmDFLGMRVVSELLRMSGAFFMRRtfGGNKLYWAVFsEYVKTMLRCG 233
Cdd:cd07989 25 PVIIVANHQSYLDPLVLGAALPRP--IRFVAKK--ELFKIPFLGWLLRLLGAIPIDR--GNGRSAREAL-REAIEALKEG 97
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160298207 234 YAPVeFFLEGTRSRAAKTLTPKFGLLNIVMEpfFKREVfdtyfVPISISydkileeslYAYEILGVPKPKESttgllkar 313
Cdd:cd07989 98 ESVV-IFPEGTRSRDGELLPFKSGAFRLAKE--AGVPI-----VPVAIS---------GTWGSLPKGKKLPR-------- 152
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170 180 190
....*....|....*....|....*....|.
gi 160298207 314 rilsenFGSIHVYFGDPVSLRSLAAGRLNRN 344
Cdd:cd07989 153 ------PGRVTVRIGEPIPPEGLELAEEDRK 177
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