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Conserved domains on  [gi|81295816|ref|NP_036469|]
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cilia- and flagella-associated protein 45 [Homo sapiens]

Protein Classification

trichohyalin-plectin-homology domain domain-containing protein( domain architecture ID 12159040)

trichohyalin-plectin-homology domain (TPH) domain-containing protein similar to meiosis-specific nuclear structural protein 1, trichoplein keratin filament-binding protein, and cilia- and flagella-associated proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 184-524 4.98e-64

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


:

Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 212.47  E-value: 4.98e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   184 RMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVE 263
Cdd:pfam13868   1 LRENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   264 QMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEF 343
Cdd:pfam13868  81 QIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   344 TKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKS 423
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   424 RLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRL 503
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERL 320

                         330       340
                  ....*....|....*....|.
gi 81295816   504 KEEAQKRRERIDEIKRKKLEE 524
Cdd:pfam13868 321 REEEAERRERIEEERQKKLKE 341
 
Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 184-524 4.98e-64

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 212.47  E-value: 4.98e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   184 RMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVE 263
Cdd:pfam13868   1 LRENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   264 QMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEF 343
Cdd:pfam13868  81 QIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   344 TKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKS 423
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   424 RLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRL 503
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERL 320

                         330       340
                  ....*....|....*....|.
gi 81295816   504 KEEAQKRRERIDEIKRKKLEE 524
Cdd:pfam13868 321 REEEAERRERIEEERQKKLKE 341
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 208-456 4.74e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.18  E-value: 4.74e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 208 DAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQI-VEQMEKNQEERSLLAEQREQEKEQM 286
Cdd:COG1196 245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELArLEQDIARLEERRRELEERLEELEEE 324

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 287 LEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKE 366
Cdd:COG1196 325 LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 367 KEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKSRLEQVAFKEHALAVQVQRDRDEF 446
Cdd:COG1196 405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                       250
                ....*....|
gi 81295816 447 ERILRAQREQ 456
Cdd:COG1196 485 ELAEAAARLL 494
PTZ00121 PTZ00121
MAEBL; Provisional
 110-526 7.32e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.00  E-value: 7.32e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   110 ERIKWASHVLTREELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANKLRMEQEE 189
Cdd:PTZ00121 1275 EEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEA 1354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   190 ELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQ 269
Cdd:PTZ00121 1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD 1434

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   270 EERSLLAEQRE-QEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKM 348
Cdd:PTZ00121 1435 EAKKKAEEAKKaDEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADE 1514

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   349 AREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKSRLEQV 428
Cdd:PTZ00121 1515 AKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARI 1594

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   429 AFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHAN-ELRRQVRENQQKEVQNRIATFEEGRRLKEEA 507
Cdd:PTZ00121 1595 EEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEaEEKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

                         410       420
                  ....*....|....*....|.
gi 81295816   508 QKRRE--RIDEIKRKKLEELR 526
Cdd:PTZ00121 1675 KKAEEakKAEEDEKKAAEALK 1695
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 170-388 1.29e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 48.29  E-value: 1.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   170 KERAQnllqrANKLRMEQEE------------ELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEverq 237
Cdd:NF012221 1564 KERAE-----ADRQRLEQEKqqqlaaisgsqsQLESTDQNALETNGQAQRDAILEESRAVTKELTTLAQGLDALDS---- 1634

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   238 ksiqrqeelerkrreerirgrrQIVEQMEKNQEERSLLAE---QREQEKEQMLEYMEQLQEEDLKDMERRQQQKLK---- 310
Cdd:NF012221 1635 ----------------------QATYAGESGDQWRNPFAGgllDRVQEQLDDAKKISGKQLADAKQRHVDNQQKVKdava 1692

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   311 ------MQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQA 384
Cdd:NF012221 1693 kseagvAQGEQNQANAEQDIDDAKADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDASAAENKANQAQADAKGA 1772


                  ....
gi 81295816   385 EQDA 388
Cdd:NF012221 1773 KQDE 1776
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 201-527 4.46e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.59  E-value: 4.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    201 AKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQK-----SIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLL 275
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLrkeleELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL 759

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    276 AEQREQEkEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQmvmefTKKKMAREAEFE 355
Cdd:TIGR02168  760 EAEIEEL-EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN-----LRERLESLERRI 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    356 AEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVadrewrrKEKENARKKMETEAELRKSRLEQVAFKEHAL 435
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL-------EALLNERASLEEALALLRSELEELSEELREL 906

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    436 AVQVQRDRDEFERiLRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRLKEEAQKRRERID 515
Cdd:TIGR02168  907 ESKRSELRRELEE-LREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELG 985

                          330
                   ....*....|..
gi 81295816    516 EIKRKKLEELRA 527
Cdd:TIGR02168  986 PVNLAAIEEYEE 997
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 260-442 5.97e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 42.90  E-value: 5.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   260 QIVEQMEKNQEERSLLAEQR---------EQEKEQMLEYME----QLQEEDLKDMERR-QQQKLKMQAEIKRINDENQK- 324
Cdd:NF012221 1546 AVSKHAKQDDAAQNALADKEraeadrqrlEQEKQQQLAAISgsqsQLESTDQNALETNgQAQRDAILEESRAVTKELTTl 1625

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   325 -QKAELL-----AQEKLADQMVMEF--------------TKKKMAREAE-----FEAEQERIRREKEKEIARLRAMQEKA 379
Cdd:NF012221 1626 aQGLDALdsqatYAGESGDQWRNPFagglldrvqeqlddAKKISGKQLAdakqrHVDNQQKVKDAVAKSEAGVAQGEQNQ 1705

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 81295816   380 QDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKSRLEQVAFKEHALAVQVQRD 442
Cdd:NF012221 1706 ANAEQDIDDAKADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDASAAENKANQAQAD 1768
 
Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 184-524 4.98e-64

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 212.47  E-value: 4.98e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   184 RMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVE 263
Cdd:pfam13868   1 LRENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   264 QMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEF 343
Cdd:pfam13868  81 QIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   344 TKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKS 423
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   424 RLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRL 503
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERL 320

                         330       340
                  ....*....|....*....|.
gi 81295816   504 KEEAQKRRERIDEIKRKKLEE 524
Cdd:pfam13868 321 REEEAERRERIEEERQKKLKE 341
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 208-456 4.74e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.18  E-value: 4.74e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 208 DAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQI-VEQMEKNQEERSLLAEQREQEKEQM 286
Cdd:COG1196 245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELArLEQDIARLEERRRELEERLEELEEE 324

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 287 LEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKE 366
Cdd:COG1196 325 LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 367 KEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKSRLEQVAFKEHALAVQVQRDRDEF 446
Cdd:COG1196 405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                       250
                ....*....|
gi 81295816 447 ERILRAQREQ 456
Cdd:COG1196 485 ELAEAAARLL 494
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 219-533 5.21e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.18  E-value: 5.21e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 219 KELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQE--E 296
Cdd:COG1196 216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEllA 295

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 297 DLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQ 376
Cdd:COG1196 296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 377 EKAQDYQAEQDALRAKRNQEVADREwrrkeKENARKKMETEAELRKSRLEQvafkehalavqvQRDRDEFERILRAQREQ 456
Cdd:COG1196 376 EAEEELEELAEELLEALRAAAELAA-----QLEELEEAEEALLERLERLEE------------ELEELEEALAELEEEEE 438

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 81295816 457 IEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRLKEEAQKRRERIDEIKRKKLEELRATGLPEK 533
Cdd:COG1196 439 EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL 515
PTZ00121 PTZ00121
MAEBL; Provisional
 110-526 7.32e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.00  E-value: 7.32e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   110 ERIKWASHVLTREELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANKLRMEQEE 189
Cdd:PTZ00121 1275 EEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEA 1354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   190 ELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQ 269
Cdd:PTZ00121 1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD 1434

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   270 EERSLLAEQRE-QEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKM 348
Cdd:PTZ00121 1435 EAKKKAEEAKKaDEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADE 1514

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   349 AREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKSRLEQV 428
Cdd:PTZ00121 1515 AKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARI 1594

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   429 AFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHAN-ELRRQVRENQQKEVQNRIATFEEGRRLKEEA 507
Cdd:PTZ00121 1595 EEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEaEEKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

                         410       420
                  ....*....|....*....|.
gi 81295816   508 QKRRE--RIDEIKRKKLEELR 526
Cdd:PTZ00121 1675 KKAEEakKAEEDEKKAAEALK 1695
PTZ00121 PTZ00121
MAEBL; Provisional
 122-544 1.81e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.38  E-value: 1.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   122 EELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLSD-----LEEV-----AKERAQNLLQRANKLRMEQEEEL 191
Cdd:PTZ00121 1339 EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADaakkkAEEKkkadeAKKKAEEDKKKADELKKAAAAKK 1418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   192 KDMSkiiLNAKCHAIRDAQILEKQQIQK------ELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQM 265
Cdd:PTZ00121 1419 KADE---AKKKAEEKKKADEAKKKAEEAkkadeaKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA 1495

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   266 EKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTK 345
Cdd:PTZ00121 1496 KKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEED 1575

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   346 KKMA-REAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAkrnQEVADREWRRKEKENARKKMETE---AELR 421
Cdd:PTZ00121 1576 KNMAlRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA---EELKKAEEEKKKVEQLKKKEAEEkkkAEEL 1652

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   422 KSRLEQVAFKEHALAVQVQRDRDEFERILRAQ-----REQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIAT 496
Cdd:PTZ00121 1653 KKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEedekkAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKA 1732

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 81295816   497 FEEGRRLKEEAQKRRE-RIDEIKRKKLEELRATGLPEKYCIEAERKANI 544
Cdd:PTZ00121 1733 EEAKKEAEEDKKKAEEaKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVI 1781
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 179-528 5.78e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.43  E-value: 5.78e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   179 RANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEvERQKSIQRQEELERKRREERIRGR 258
Cdd:pfam17380 259 RYNGQTMTENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVE-RRRKLEEAEKARQAEMDRQAAIYA 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   259 RQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQ 338
Cdd:pfam17380 338 EQERMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQ 417

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   339 MVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRamqEKAQDYQAEQDALRakrnQEVADREWRRKEKENARKKMETEA 418
Cdd:pfam17380 418 QKVEMEQIRAEQEEARQREVRRLEEERAREMERVR---LEEQERQQQVERLR----QQEEERKRKKLELEKEKRDRKRAE 490

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   419 ELRKSRLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVREnqqkevQNRIATFE 498
Cdd:pfam17380 491 EQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQE------QMRKATEE 564

                         330       340       350
                  ....*....|....*....|....*....|
gi 81295816   499 EGRRLKEEAQKRRERIDEIKRKKLEELRAT 528
Cdd:pfam17380 565 RSRLEAMEREREMMRQIVESEKARAEYEAT 594
PTZ00121 PTZ00121
MAEBL; Provisional
 122-526 8.81e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.07  E-value: 8.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   122 EELEARDQAFKKEKEATMDAVMTRKKIMKQKEMvwNNNKKLSDLEEVAKE--RAQNLLQRANKLRMEQE-----EELKDM 194
Cdd:PTZ00121 1408 DELKKAAAAKKKADEAKKKAEEKKKADEAKKKA--EEAKKADEAKKKAEEakKAEEAKKKAEEAKKADEakkkaEEAKKA 1485

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   195 SKIILNAKCHAIRDAQILEKQQIQKELDT-----EEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQ 269
Cdd:PTZ00121 1486 DEAKKKAEEAKKKADEAKKAAEAKKKADEakkaeEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKK 1565

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   270 EERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRiNDENQKQKAELLAQEKLADQMVMEFTKKkma 349
Cdd:PTZ00121 1566 AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAK-KAEEAKIKAEELKKAEEEKKKVEQLKKK--- 1641

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   350 rEAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKmeteAELRKSRLEQVA 429
Cdd:PTZ00121 1642 -EAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKA----EELKKKEAEEKK 1716

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   430 FKEhalavqvQRDRDEFERILRAqrEQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRLKEEAQK 509
Cdd:PTZ00121 1717 KAE-------ELKKAEEENKIKA--EEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDE 1787

                         410
                  ....*....|....*..
gi 81295816   510 RRERIDEIKRKKLEELR 526
Cdd:PTZ00121 1788 EDEKRRMEVDKKIKDIF 1804
PTZ00121 PTZ00121
MAEBL; Provisional
 110-419 9.19e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.07  E-value: 9.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   110 ERIKWASHVLTREELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANKLRMEQEE 189
Cdd:PTZ00121 1513 DEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEA 1592

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   190 ELKDMSKIILNAKCHAIRDAQILEKQQIQKEldteekrldqmmEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQ 269
Cdd:PTZ00121 1593 RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE------------ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENK 1660

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   270 EERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKmA 349
Cdd:PTZ00121 1661 IKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE-A 1739

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   350 REAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADrEWRRKEKENARKKMETEAE 419
Cdd:PTZ00121 1740 EEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEED-EKRRMEVDKKIKDIFDNFA 1808
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 143-456 3.47e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 49.74  E-value: 3.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   143 MTRKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRA------NKLRMEQEEELKDMSKIILNAKCHAIRDAQIL---- 212
Cdd:pfam17380 296 MEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAaiyaeqERMAMERERELERIRQEERKRELERIRQEEIAmeis 375

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   213 ---EKQQIQKELDTEEKRLDQMMEVERQKSIQRQeelerkrreerirgrrqivEQMEKNQEERSLLAEQREQEKEQMLEY 289
Cdd:pfam17380 376 rmrELERLQMERQQKNERVRQELEAARKVKILEE-------------------ERQRKIQQQKVEMEQIRAEQEEARQRE 436

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   290 MEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEI 369
Cdd:pfam17380 437 VRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRK 516

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   370 ARLRAMQEkaqdyqaeqdalrakRNQEVADREWRRKEKENARKKMETEAELRKSRLEQVAFKEHALAVQVQRDRDEFERI 449
Cdd:pfam17380 517 LLEKEMEE---------------RQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQI 581


                  ....*..
gi 81295816   450 LRAQREQ 456
Cdd:pfam17380 582 VESEKAR 588
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 121-530 4.91e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.55  E-value: 4.91e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 121 REELEARDQAFKKEKEATMDAVMTRKKIMKQKEMvwnNNKKLSDLEEVAKERAQNLLQRANKLRMEQEEELKDMSKIILN 200
Cdd:COG1196 273 RLELEELELELEEAQAEEYELLAELARLEQDIAR---LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA 349

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 201 AKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQRE 280
Cdd:COG1196 350 EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEA 429

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 281 QEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEI--KRINDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQ 358
Cdd:COG1196 430 LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELlaELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG 509

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 359 ERIRREKEKEIARLRAMQEKAQD----YQAEQDALRAKRNQEVADREWRRKEKENARKK----------METEAELRKSR 424
Cdd:COG1196 510 VKAALLLAGLRGLAGAVAVLIGVeaayEAALEAALAAALQNIVVEDDEVAAAAIEYLKAakagratflpLDKIRARAALA 589

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 425 LEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRLK 504
Cdd:COG1196 590 AALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRE 669

                       410       420
                ....*....|....*....|....*.
gi 81295816 505 EEAQKRRERIDEIKRKKLEELRATGL 530
Cdd:COG1196 670 LLAALLEAEAELEELAERLAEEELEL 695
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 170-388 1.29e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 48.29  E-value: 1.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   170 KERAQnllqrANKLRMEQEE------------ELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEverq 237
Cdd:NF012221 1564 KERAE-----ADRQRLEQEKqqqlaaisgsqsQLESTDQNALETNGQAQRDAILEESRAVTKELTTLAQGLDALDS---- 1634

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   238 ksiqrqeelerkrreerirgrrQIVEQMEKNQEERSLLAE---QREQEKEQMLEYMEQLQEEDLKDMERRQQQKLK---- 310
Cdd:NF012221 1635 ----------------------QATYAGESGDQWRNPFAGgllDRVQEQLDDAKKISGKQLADAKQRHVDNQQKVKdava 1692

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   311 ------MQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQA 384
Cdd:NF012221 1693 kseagvAQGEQNQANAEQDIDDAKADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDASAAENKANQAQADAKGA 1772


                  ....
gi 81295816   385 EQDA 388
Cdd:NF012221 1773 KQDE 1776
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 201-527 4.46e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.59  E-value: 4.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    201 AKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQK-----SIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLL 275
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLrkeleELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL 759

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    276 AEQREQEkEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQmvmefTKKKMAREAEFE 355
Cdd:TIGR02168  760 EAEIEEL-EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN-----LRERLESLERRI 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    356 AEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVadrewrrKEKENARKKMETEAELRKSRLEQVAFKEHAL 435
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL-------EALLNERASLEEALALLRSELEELSEELREL 906

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    436 AVQVQRDRDEFERiLRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRLKEEAQKRRERID 515
Cdd:TIGR02168  907 ESKRSELRRELEE-LREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELG 985

                          330
                   ....*....|..
gi 81295816    516 EIKRKKLEELRA 527
Cdd:TIGR02168  986 PVNLAAIEEYEE 997
PTZ00491 PTZ00491
major vault protein; Provisional
 262-428 4.63e-05

major vault protein; Provisional


Pssm-ID: 240439 [Multi-domain]  Cd Length: 850  Bit Score: 46.16  E-value: 4.63e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816  262 VEQMEKNQE-ERSLLAEQREQEKEQMLEymeqlqeedlkdmerrqQQKLKMQAEikrindeNQKQKAELLAQEklADQMV 340
Cdd:PTZ00491 657 IEITTKSQEaAARHQAELLEQEARGRLE-----------------RQKMHDKAK-------AEEQRTKLLELQ--AESAA 710

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816  341 MEFTKKKMArEAEFEAEQERIRREKEKEIARLRAmqeKAQD--YQAEQDALRAKRNQEVadrEWRRKEKENARKKMETEA 418
Cdd:PTZ00491 711 VESSGQSRA-EALAEAEARLIEAEAEVEQAELRA---KALRieAEAELEKLRKRQELEL---EYEQAQNELEIAKAKELA 783

                        170
                 ....*....|
gi 81295816  419 ELRKSRLEQV 428
Cdd:PTZ00491 784 DIEATKFERI 793
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 260-526 6.07e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.20  E-value: 6.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    260 QIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQklkmqAEIKRINDENQKQKAELLAQEKLADQM 339
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEI-----EELQKELYALANEISRLEQQKQILRER 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    340 VMEFTKKKmareAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAE 419
Cdd:TIGR02168  311 LANLERQL----EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    420 LRKSRLEQVAfkehalavqvqrdrdeferILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEE 499
Cdd:TIGR02168  387 KVAQLELQIA-------------------SLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEE 447

                          250       260
                   ....*....|....*....|....*..
gi 81295816    500 GRRLKEEAQKRRERIDEIKRKKLEELR 526
Cdd:TIGR02168  448 ELEELQEELERLEEALEELREELEEAE 474
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 261-419 1.01e-04

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 44.80  E-value: 1.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816  261 IVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQklkmqaEIKRINDENQKQKAELLAQEKLADQMV 340
Cdd:PRK09510  60 VVEQYNRQQQQQKSAKRAEEQRKKKEQQQAEELQQKQAAEQERLKQL------EKERLAAQEQKKQAEEAAKQAALKQKQ 133

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 81295816  341 MEFTKKKMAREAEFEAEQErirrEKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAE 419
Cdd:PRK09510 134 AEEAAAKAAAAAKAKAEAE----AKRAAAAAKKAAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAEAK 208
Caldesmon pfam02029
Caldesmon;
164-524 1.60e-04

Caldesmon;


Pssm-ID: 460421 [Multi-domain]  Cd Length: 495  Bit Score: 44.47  E-value: 1.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   164 DLEEVAKERAQNllQRANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQM--MEVERQKSIQ 241
Cdd:pfam02029   3 DEEEAARERRRR--AREERRRQKEEEEPSGQVTESVEPNEHNSYEEDSELKPSGQGGLDEEEAFLDRTakREERRQKRLQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   242 RQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDE 321
Cdd:pfam02029  81 EALERQKEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTEVRQAEEEGEEEE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   322 NQKQKAELLAQEKLADQMVMEFTKKKmareaefeaEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADRE 401
Cdd:pfam02029 161 DKSEEAEEVPTENFAKEEVKDEKIKK---------EKKVKYESKVFLDQKRGHPEVKSQNGEEEVTKLKVTTKRRQGGLS 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   402 WRRKEKENARKKMETEAELRKSRLEQVAfkehalavqvqRDRDEFERILRAQREQIEKERLeeekkatgrLQHANELRRQ 481
Cdd:pfam02029 232 QSQEREEEAEVFLEAEQKLEELRRRRQE-----------KESEEFEKLRQKQQEAELELEE---------LKKKREERRK 291

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 81295816   482 VRENQ-----QKEVQNRIATFEEGRRLKEEAQKRRERIDEiKRKKLEE 524
Cdd:pfam02029 292 LLEEEeqrrkQEEAERKLREEEEKRRMKEEIERRRAEAAE-KRQKLPE 338
PRK12704 PRK12704
phosphodiesterase; Provisional
 339-514 1.86e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.00  E-value: 1.86e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816  339 MVMEFTKKKMAREAEFEA----EQERIRREKEKEIARLRAmQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKM 414
Cdd:PRK12704  23 FVRKKIAEAKIKEAEEEAkrilEEAKKEAEAIKKEALLEA-KEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRK 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816  415 ETEAELRKSRLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATgrlqhaNELRRQVRENQQKEVQNRI 494
Cdd:PRK12704 102 LELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEEAK------EILLEKVEEEARHEAAVLI 175

                        170       180
                 ....*....|....*....|
gi 81295816  495 ATFEEgrRLKEEAQKRRERI 514
Cdd:PRK12704 176 KEIEE--EAKEEADKKAKEI 193
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 303-525 1.96e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.28  E-value: 1.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    303 RRQQQKLKMQAEI----KRINDENQKQKAELLAQEKLADQMVMEFTKKKMAR-EAEFEAEQERIrREKEKEIARLRA--- 374
Cdd:TIGR02168  199 ERQLKSLERQAEKaeryKELKAELRELELALLVLRLEELREELEELQEELKEaEEELEELTAEL-QELEEKLEELRLevs 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    375 -MQEKAQDYQAEQDALRAKRN---QEVADREWRRKEKENARKKMETEAELRKSRLEQVAFKEHALAVQVQRDRDEFERiL 450
Cdd:TIGR02168  278 eLEEEIEELQKELYALANEISrleQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELES-L 356

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 81295816    451 RAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRiATFEEGRRLKEEAQKRRERIDEIKRKKLEEL 525
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN-NEIERLEARLERLEDRRERLQQEIEELLKKL 430
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 121-520 2.13e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.16  E-value: 2.13e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 121 REELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNN-NKKLSDLEEVAKERAQNLLQRANKLRMEQEEELKDMSKIIL 199
Cdd:COG1196 325 LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEaEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 200 NAKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQK--SIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAE 277
Cdd:COG1196 405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAleEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 278 QREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRI-----------------------------NDENQKQKAE 328
Cdd:COG1196 485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvavligveaayeaaleaalaaalqnivveDDEVAAAAIE 564

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 329 LLAQEKLA--------------------DQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDA 388
Cdd:COG1196 565 YLKAAKAGratflpldkiraraalaaalARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAG 644

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 389 LRAKRNQEVADREWRRKEKENARKKMETEAELRKSRLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKA 468
Cdd:COG1196 645 RLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|..
gi 81295816 469 TgRLQHANELRRQVRENQQKEVQNRIATFEEGRRLKEEAQKRRERIDEIKRK 520
Cdd:COG1196 725 A-LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
PTZ00121 PTZ00121
MAEBL; Provisional
 160-526 3.56e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.59  E-value: 3.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   160 KKLSDLEEVAKERAQNLLQRANKLRMEQEEELKDMSKIILNAKchaiRDAQILEKQQIQKELDTEEKRLDQMMEVERQKS 239
Cdd:PTZ00121 1194 RKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAK----KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQ 1269

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   240 IQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDME--RRQQQKLKMQAEIKR 317
Cdd:PTZ00121 1270 AAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADaaKKKAEEAKKAAEAAK 1349

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   318 INDENQKQKAELLAQEKLADQMVMEFTKKKmAREAEFEAEQERIRREKEKeiarlRAMQEKAQDYQAEQDALRAKRNQEV 397
Cdd:PTZ00121 1350 AEAEAAADEAEAAEEKAEAAEKKKEEAKKK-ADAAKKKAEEKKKADEAKK-----KAEEDKKKADELKKAAAAKKKADEA 1423

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   398 ADREWRRKEKENARKKMEteaELRKSRLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANE 477
Cdd:PTZ00121 1424 KKKAEEKKKADEAKKKAE---EAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKAD 1500

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 81295816   478 LRRQVRENQQKEVQNRIAtfeEGRRLKEEAQKRRERIDEIKRKKLEELR 526
Cdd:PTZ00121 1501 EAKKAAEAKKKADEAKKA---EEAKKADEAKKAEEAKKADEAKKAEEKK 1546
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 260-442 5.97e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 42.90  E-value: 5.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   260 QIVEQMEKNQEERSLLAEQR---------EQEKEQMLEYME----QLQEEDLKDMERR-QQQKLKMQAEIKRINDENQK- 324
Cdd:NF012221 1546 AVSKHAKQDDAAQNALADKEraeadrqrlEQEKQQQLAAISgsqsQLESTDQNALETNgQAQRDAILEESRAVTKELTTl 1625

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   325 -QKAELL-----AQEKLADQMVMEF--------------TKKKMAREAE-----FEAEQERIRREKEKEIARLRAMQEKA 379
Cdd:NF012221 1626 aQGLDALdsqatYAGESGDQWRNPFagglldrvqeqlddAKKISGKQLAdakqrHVDNQQKVKDAVAKSEAGVAQGEQNQ 1705

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 81295816   380 QDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKSRLEQVAFKEHALAVQVQRD 442
Cdd:NF012221 1706 ANAEQDIDDAKADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDASAAENKANQAQAD 1768
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 213-399 1.22e-03

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 41.33  E-value: 1.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816  213 EKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAE--QREQEKEQMLEYM 290
Cdd:PRK09510  79 EQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAKAAAaaKAKAEAEAKRAAA 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816  291 EQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQmvmefTKKKMAREAEFEAEQERiRREKEKEIA 370
Cdd:PRK09510 159 AAKKAAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAE-----AKKKAAAEAKKKAAAEA-KAAAAKAAA 232

                        170       180
                 ....*....|....*....|....*....
gi 81295816  371 RLRAMQEKAQDYQAEQDALRAKRNQEVAD 399
Cdd:PRK09510 233 EAKAAAEKAAAAKAAEKAAAAKAAAEVDD 261
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 122-401 3.77e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 40.44  E-value: 3.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    122 EELEARDQAFKKEKEATMDAVMTRKKIMKQKEmvwnnnKKLSDLEEvAKERAQNLLQRANKLRMEQEEELKDMskiilna 201
Cdd:TIGR02169  677 QRLRERLEGLKRELSSLQSELRRIENRLDELS------QELSDASR-KIGEIEKEIEQLEQEEEKLKERLEEL------- 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    202 kchairDAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLL------ 275
Cdd:TIGR02169  743 ------EEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIearlre 816

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816    276 AEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIkrinDENQKQKAELLAQEkladqmvmeftKKKMAREAEFE 355
Cdd:TIGR02169  817 IEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEI----ENLNGKKEELEEEL-----------EELEAALRDLE 881

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 81295816    356 AEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADRE 401
Cdd:TIGR02169  882 SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927
PTZ00121 PTZ00121
MAEBL; Provisional
 226-542 5.92e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 5.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   226 KRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIveqmeKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQ 305
Cdd:PTZ00121 1158 RKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEEL-----RKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKA 1232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   306 QQKLKMQAEIKRINDENQKQKAELLAQEKLAdqmvmEFTKKKMAREAEFEAEQERIRREKEKEIA-RLRAMQEKAQDYQA 384
Cdd:PTZ00121 1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMA-----HFARRQAAIKAEEARKADELKKAEEKKKAdEAKKAEEKKKADEA 1307

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   385 EQDALRAKRNQEVADREWRRKEKENARKKmetEAELRKSRLEQVAFKEHALAVQVQRDRDEFERILRAQREQieKERLEE 464
Cdd:PTZ00121 1308 KKKAEEAKKADEAKKKAEEAKKKADAAKK---KAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEA--KKKADA 1382

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816   465 EKKATGRLQHANELRRQVRENQQK--EVQNRIATFEEGRRLKEEAQKRReRIDEIKRKKLEELRATGLPEKycIEAERKA 542
Cdd:PTZ00121 1383 AKKKAEEKKKADEAKKKAEEDKKKadELKKAAAAKKKADEAKKKAEEKK-KADEAKKKAEEAKKADEAKKK--AEEAKKA 1459
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 358-527 7.47e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.98  E-value: 7.47e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 358 QERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKSRLEQVAFKEHALAV 437
Cdd:COG4942  18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816 438 QVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELR--RQVRENQQKEVQNRIATFEEGRRLKEEAQKRRERID 515
Cdd:COG4942  98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQylKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                       170
                ....*....|..
gi 81295816 516 EIKRKKLEELRA 527
Cdd:COG4942 178 ALLAELEEERAA 189
PRK13878 PRK13878
conjugal transfer relaxase TraI; Provisional
 342-431 8.42e-03

conjugal transfer relaxase TraI; Provisional


Pssm-ID: 237539 [Multi-domain]  Cd Length: 746  Bit Score: 38.94  E-value: 8.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816  342 EFTKKKM-AREAEFEAEQERI-----RREKEKEIARLRA-MQEKAQDYQAEQDALRAKRNQEVAdrewrrkeKENARKKM 414
Cdd:PRK13878 239 DLSKPKLeARLGPFEPSPERQaqtkaKRQYRKDPIRLRVnTVELYAKYKAEQQTLTAARAQALE--------RARRRKDR 310

                         90
                 ....*....|....*..
gi 81295816  415 ETEAELRKSRLEQVAFK 431
Cdd:PRK13878 311 LIEAAKRSNRLRRAAIK 327
PRK05035 PRK05035
electron transport complex protein RnfC; Provisional
 326-422 9.30e-03

electron transport complex protein RnfC; Provisional


Pssm-ID: 235334 [Multi-domain]  Cd Length: 695  Bit Score: 38.78  E-value: 9.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816  326 KAELLAQEKladqmvmeftKKKMAREAE--FEAEQERIRREKEKEIARLR--AMQEKAQDYQAEQDAL-RAKRNQEVADR 400
Cdd:PRK05035 435 KAEIRAIEQ----------EKKKAEEAKarFEARQARLEREKAAREARHKkaAEARAAKDKDAVAAALaRVKAKKAAATQ 504

                         90       100
                 ....*....|....*....|...
gi 81295816  401 EWRRK-EKENARKKMETEAELRK 422
Cdd:PRK05035 505 PIVIKaGARPDNSAVIAAREARK 527
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 280-419 9.87e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 38.65  E-value: 9.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81295816  280 EQEKEQMLEYMEQLQE--EDLKDMERRQQQKLKmQAEIKRinDENQKQKAELLAQ-EKLADQmvmeftKKKMAREAEFEA 356
Cdd:PRK00409 505 EEAKKLIGEDKEKLNEliASLEELERELEQKAE-EAEALL--KEAEKLKEELEEKkEKLQEE------EDKLLEEAEKEA 575

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 81295816  357 EQ--ERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVAdrewrRKEKENARKKMETEAE 419
Cdd:PRK00409 576 QQaiKEAKKEADEIIKELRQLQKGGYASVKAHELIEARKRLNKA-----NEKKEKKKKKQKEKQE 635
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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