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Conserved domains on  [gi|77539456|ref|NP_036648|]
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C4b-binding protein alpha chain [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 83-301 2.19e-50

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 175.23  E-value: 2.19e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456   83 TLRYNCRPGYsRASSSQSLYCKPLGK-WQINIACVKKSCRNPGDLQNGKVEVK-TDFlfGSQIEFSCSEGYILIGSSTSY 160
Cdd:PHA02927  49 TIEYLCLPGY-RKQKMGPIYAKCTGTgWTLFNQCIKRRCPSPRDIDNGQLDIGgVDF--GSSITYSCNSGYQLIGESKSY 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  161 CEIQGKG-VSWSDPLPECVIAKCGMPPDISNGKHNGREEeFFTYRSSVTYKCDPDFTLLGNASITCTVvnktvGVWSpSP 239
Cdd:PHA02927 126 CELGSTGsMVWNPEAPICESVKCQSPPSISNGRHNGYED-FYTDGSVVTYSCNSGYSLIGNSGVLCSG-----GEWS-DP 198

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 77539456  240 PTCERIICPWPKVLHGTINSGFKHTYKYKDSVRFVCQKGFVLRGSGVIHCEADGSWSP-VPVC 301
Cdd:PHA02927 199 PTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPeLPKC 261
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 300-544 1.67e-32

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 125.92  E-value: 1.67e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  300 VCELNSCTdIPDIP-NAALITSPRPRKEDVYPVGTVLRYICRPGYEPATRQPMTVICQKDlSWSMLRGCKEICCPvpDPK 378
Cdd:PHA02927  15 GCVLSCCT-IPSRPiNMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GWTLFNQCIKRRCP--SPR 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  379 SVRVIQHEKAHPDndctyfFGDEVSYTCQNDIMLTATCKS--------DGTWHPRTPSCHQ-SCDFPPAIAHGRYTKSSS 449
Cdd:PHA02927  91 DIDNGQLDIGGVD------FGSSITYSCNSGYQLIGESKSycelgstgSMVWNPEAPICESvKCQSPPSISNGRHNGYED 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  450 YYVR-TQVTYECEEGYRLVGEATISCWYSQWTPAaPQCKAL-CRKPEIGNGVLSTN-KDQYVETENVTIQCDSGFVMLGS 526
Cdd:PHA02927 165 FYTDgSVVTYSCNSGYSLIGNSGVLCSGGEWSDP-PTCQIVkCPHPTISNGYLSSGfKRSYSYNDNVDFKCKYGYKLSGS 243

                        250
                 ....*....|....*...
gi 77539456  527 QSITCSENGTWYPKVPRC 544
Cdd:PHA02927 244 SSSTCSPGNTWQPELPKC 261
C4bp_oligo pfam18453
Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization ...
 547-595 3.31e-28

Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization domain found in C4b-binding protein (C4BP), which contains 14 cysteines that form 7 intermolecular disulfide bridges. C4BP is a plasma glycoprotein complex of 570 kDa, which is mainly produced in the liver. C4BP is the major inhibitor of complement activation, the major isoform consists of 7alpha and one beta-chain where each alpha-chain comprises eight complement control domain proteins (CCPs) and a C-terminal oligomerization domain. This domain carries a stretch of 42-45 amino acids that has been shown to be required for ring formation.


:

Pssm-ID: 436513  Cd Length: 49  Bit Score: 106.76  E-value: 3.31e-28
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 77539456   547 EVPKDCEHVFAGKKLMQCLPNSNDVKMALEVYKLTLEIKQLQLQIDKAK 595
Cdd:pfam18453   1 EFPEGCEQVLTGKKLMQCLPNPEDVKMALEVYKLSLEIELLELQIDKAK 49
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 83-301 2.19e-50

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 175.23  E-value: 2.19e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456   83 TLRYNCRPGYsRASSSQSLYCKPLGK-WQINIACVKKSCRNPGDLQNGKVEVK-TDFlfGSQIEFSCSEGYILIGSSTSY 160
Cdd:PHA02927  49 TIEYLCLPGY-RKQKMGPIYAKCTGTgWTLFNQCIKRRCPSPRDIDNGQLDIGgVDF--GSSITYSCNSGYQLIGESKSY 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  161 CEIQGKG-VSWSDPLPECVIAKCGMPPDISNGKHNGREEeFFTYRSSVTYKCDPDFTLLGNASITCTVvnktvGVWSpSP 239
Cdd:PHA02927 126 CELGSTGsMVWNPEAPICESVKCQSPPSISNGRHNGYED-FYTDGSVVTYSCNSGYSLIGNSGVLCSG-----GEWS-DP 198

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 77539456  240 PTCERIICPWPKVLHGTINSGFKHTYKYKDSVRFVCQKGFVLRGSGVIHCEADGSWSP-VPVC 301
Cdd:PHA02927 199 PTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPeLPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 300-544 1.67e-32

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 125.92  E-value: 1.67e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  300 VCELNSCTdIPDIP-NAALITSPRPRKEDVYPVGTVLRYICRPGYEPATRQPMTVICQKDlSWSMLRGCKEICCPvpDPK 378
Cdd:PHA02927  15 GCVLSCCT-IPSRPiNMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GWTLFNQCIKRRCP--SPR 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  379 SVRVIQHEKAHPDndctyfFGDEVSYTCQNDIMLTATCKS--------DGTWHPRTPSCHQ-SCDFPPAIAHGRYTKSSS 449
Cdd:PHA02927  91 DIDNGQLDIGGVD------FGSSITYSCNSGYQLIGESKSycelgstgSMVWNPEAPICESvKCQSPPSISNGRHNGYED 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  450 YYVR-TQVTYECEEGYRLVGEATISCWYSQWTPAaPQCKAL-CRKPEIGNGVLSTN-KDQYVETENVTIQCDSGFVMLGS 526
Cdd:PHA02927 165 FYTDgSVVTYSCNSGYSLIGNSGVLCSGGEWSDP-PTCQIVkCPHPTISNGYLSSGfKRSYSYNDNVDFKCKYGYKLSGS 243

                        250
                 ....*....|....*...
gi 77539456  527 QSITCSENGTWYPKVPRC 544
Cdd:PHA02927 244 SSSTCSPGNTWQPELPKC 261
C4bp_oligo pfam18453
Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization ...
 547-595 3.31e-28

Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization domain found in C4b-binding protein (C4BP), which contains 14 cysteines that form 7 intermolecular disulfide bridges. C4BP is a plasma glycoprotein complex of 570 kDa, which is mainly produced in the liver. C4BP is the major inhibitor of complement activation, the major isoform consists of 7alpha and one beta-chain where each alpha-chain comprises eight complement control domain proteins (CCPs) and a C-terminal oligomerization domain. This domain carries a stretch of 42-45 amino acids that has been shown to be required for ring formation.


Pssm-ID: 436513  Cd Length: 49  Bit Score: 106.76  E-value: 3.31e-28
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 77539456   547 EVPKDCEHVFAGKKLMQCLPNSNDVKMALEVYKLTLEIKQLQLQIDKAK 595
Cdd:pfam18453   1 EFPEGCEQVLTGKKLMQCLPNPEDVKMALEVYKLSLEIELLELQIDKAK 49
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 182-243 2.28e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 64.79  E-value: 2.28e-13
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 77539456 182 CGMPPDISNGKHNGREEEFfTYRSSVTYKCDPDFTLLGNASITCTVvnktVGVWSPSPPTCE 243
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSY-SYGSTVTYSCNEGYTLVGSSTITCTE----NGGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 433-487 6.97e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.55  E-value: 6.97e-12
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 77539456 433 CDFPPAIAHGRYT-KSSSYYVRTQVTYECEEGYRLVGEATISCW-YSQWTPAAPQCK 487
Cdd:cd00033   1 CPPPPVPENGTVTgSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
490-544 2.41e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 59.05  E-value: 2.41e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 77539456   490 CRKPE-IGNGVLSTNKDQYVETENVTIQCDSGFVMLGSQSITCSENGTWYPKVPRC 544
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 433-486 3.82e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 58.69  E-value: 3.82e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 77539456    433 CDFPPAIAHGRYTKSSSYY-VRTQVTYECEEGYRLVGEATISCWYS-QWTPAAPQC 486
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYsYGDTVTYSCDPGYTLIGSSTITCLENgTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 182-242 6.73e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.92  E-value: 6.73e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 77539456    182 CGMPPDISNGKHNGREEEFfTYRSSVTYKCDPDFTLLGNASITCTvvnkTVGVWSPSPPTC 242
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTY-SYGDTVTYSCDPGYTLIGSSTITCL----ENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
182-242 1.93e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.66  E-value: 1.93e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 77539456   182 CGMPPDISNGKHNGREEEFFtYRSSVTYKCDPDFTLLGNASITCTvvnkTVGVWSPSPPTC 242
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYN-YGASVSYECDPGYRLVGSPTITCQ----EDGTWSPPFPEC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 83-301 2.19e-50

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 175.23  E-value: 2.19e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456   83 TLRYNCRPGYsRASSSQSLYCKPLGK-WQINIACVKKSCRNPGDLQNGKVEVK-TDFlfGSQIEFSCSEGYILIGSSTSY 160
Cdd:PHA02927  49 TIEYLCLPGY-RKQKMGPIYAKCTGTgWTLFNQCIKRRCPSPRDIDNGQLDIGgVDF--GSSITYSCNSGYQLIGESKSY 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  161 CEIQGKG-VSWSDPLPECVIAKCGMPPDISNGKHNGREEeFFTYRSSVTYKCDPDFTLLGNASITCTVvnktvGVWSpSP 239
Cdd:PHA02927 126 CELGSTGsMVWNPEAPICESVKCQSPPSISNGRHNGYED-FYTDGSVVTYSCNSGYSLIGNSGVLCSG-----GEWS-DP 198

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 77539456  240 PTCERIICPWPKVLHGTINSGFKHTYKYKDSVRFVCQKGFVLRGSGVIHCEADGSWSP-VPVC 301
Cdd:PHA02927 199 PTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPeLPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 300-544 1.67e-32

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 125.92  E-value: 1.67e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  300 VCELNSCTdIPDIP-NAALITSPRPRKEDVYPVGTVLRYICRPGYEPATRQPMTVICQKDlSWSMLRGCKEICCPvpDPK 378
Cdd:PHA02927  15 GCVLSCCT-IPSRPiNMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GWTLFNQCIKRRCP--SPR 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  379 SVRVIQHEKAHPDndctyfFGDEVSYTCQNDIMLTATCKS--------DGTWHPRTPSCHQ-SCDFPPAIAHGRYTKSSS 449
Cdd:PHA02927  91 DIDNGQLDIGGVD------FGSSITYSCNSGYQLIGESKSycelgstgSMVWNPEAPICESvKCQSPPSISNGRHNGYED 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  450 YYVR-TQVTYECEEGYRLVGEATISCWYSQWTPAaPQCKAL-CRKPEIGNGVLSTN-KDQYVETENVTIQCDSGFVMLGS 526
Cdd:PHA02927 165 FYTDgSVVTYSCNSGYSLIGNSGVLCSGGEWSDP-PTCQIVkCPHPTISNGYLSSGfKRSYSYNDNVDFKCKYGYKLSGS 243

                        250
                 ....*....|....*...
gi 77539456  527 QSITCSENGTWYPKVPRC 544
Cdd:PHA02927 244 SSSTCSPGNTWQPELPKC 261
C4bp_oligo pfam18453
Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization ...
 547-595 3.31e-28

Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization domain found in C4b-binding protein (C4BP), which contains 14 cysteines that form 7 intermolecular disulfide bridges. C4BP is a plasma glycoprotein complex of 570 kDa, which is mainly produced in the liver. C4BP is the major inhibitor of complement activation, the major isoform consists of 7alpha and one beta-chain where each alpha-chain comprises eight complement control domain proteins (CCPs) and a C-terminal oligomerization domain. This domain carries a stretch of 42-45 amino acids that has been shown to be required for ring formation.


Pssm-ID: 436513  Cd Length: 49  Bit Score: 106.76  E-value: 3.31e-28
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 77539456   547 EVPKDCEHVFAGKKLMQCLPNSNDVKMALEVYKLTLEIKQLQLQIDKAK 595
Cdd:pfam18453   1 EFPEGCEQVLTGKKLMQCLPNPEDVKMALEVYKLSLEIELLELQIDKAK 49
PHA02639 PHA02639
EEV host range protein; Provisional
 120-308 2.13e-24

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 103.59  E-value: 2.13e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  120 CRNPGDLQNGKV-EVKTDFLFGSQIEFSCSEGYILIGSSTSYCEIQGKGVSWSDPLPECVIAKCGMPPDISNGK-HNGRe 197
Cdd:PHA02639  22 CDKPDDISNGFItELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFCMLKECNDPPSIINGKiYNKR- 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  198 eEFFTYRSSVTYKCDP----DFTLLGNASITCTvVNKTvgvWSPSPPTCERIICPWPKVLHGTINS-GFKHTYKYKDSVR 272
Cdd:PHA02639 101 -EMYKVGDEIYYVCNEhkgvQYSLVGNEKITCI-QDKS---WKPDPPICKMINCRFPALQNGYINGiPSNKKFYYKTRVG 175

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 77539456  273 FVCQKGFVLRGSGVIHCEADGSWSP-VPVCELNSCTD 308
Cdd:PHA02639 176 FSCKSGFDLVGEKYSTCNINATWFPsIPTCVRNKPID 212
PHA02639 PHA02639
EEV host range protein; Provisional
 364-551 1.13e-21

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 95.50  E-value: 1.13e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  364 LRGCKEICCPVPDPKSVRVIQH--EKahpdndctYFFGDEVSYTCQNDIMLTA----TC---KSDGTWHPRTPSCH-QSC 433
Cdd:PHA02639  14 VHGVKSIYCDKPDDISNGFITElmEK--------YEIGKLIEYTCNTDYALIGdrfrTCikdKNNAIWSNKAPFCMlKEC 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  434 DFPPAIAHGR-YTKSSSYYVRTQVTYECEE----GYRLVGEATISCWYSQ-WTPAAPQCKAL-CRKPEIGNGVLS---TN 503
Cdd:PHA02639  86 NDPPSIINGKiYNKREMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKsWKPDPPICKMInCRFPALQNGYINgipSN 165

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 77539456  504 KDQYVETEnVTIQCDSGFVMLGSQSITCSENGTWYPKVPRCEQEVPKD 551
Cdd:PHA02639 166 KKFYYKTR-VGFSCKSGFDLVGEKYSTCNINATWFPSIPTCVRNKPID 212
PHA02831 PHA02831
EEV host range protein; Provisional
 376-544 3.33e-20

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 90.82  E-value: 3.33e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  376 DPKSVRVIQHE-KAHPDND-----CTYFFgDEVSYTCQNdimltatcksdGTWHPRTpSC--HQSCDFPPAIAHGRY-TK 446
Cdd:PHA02831  26 DAKYSNVDSYEnKVYEENEnleykCNNNF-DKVFVTCNN-----------GSWSTKN-MCigKRNCKDPVTILNGYIkNK 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  447 SSSYYVRTQVTYECE----EGYRLVGEATISCWYSQWTPAAPQCKAL-CRKPEIGNGVLSTNKDQYVETENVTIQCDSGF 521
Cdd:PHA02831  93 KDQYSFGDSVTYACKvnklEKYSIVGNETVKCINKQWVPKYPVCKLIrCKYPALQNGFLNVFEKKFYYGDIVNFKCKKGF 172

                        170       180
                 ....*....|....*....|...
gi 77539456  522 VMLGSQSITCSENGTWYPKVPRC 544
Cdd:PHA02831 173 ILLGSSVSTCDINSIWYPGIPKC 195
PHA02817 PHA02817
EEV Host range protein; Provisional
 177-307 1.33e-18

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 84.99  E-value: 1.33e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  177 CVIAKCGMPPDISNGKHNGREEEFfTYRSSVTYKCDPD-----FTLLGNASITCtvvNKTvGVWSPSPPTCERIICPWPK 251
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYNKKTEY-NIGSNVTFFCGNNtrgvrYTLVGEKNIIC---EKD-GKWNKEFPVCKIIRCRFPA 93

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 77539456  252 VLHGTINsGFKHTYK--YKDSVRFVCQKGFVLRGSGVIHCEADGSWSP-VPVCELNSCT 307
Cdd:PHA02817  94 LQNGFVN-GIPDSKKfyYESEVSFSCKPGFVLIGTKYSVCGINSSWIPkVPICSRDNIT 151
PHA02817 PHA02817
EEV Host range protein; Provisional
 433-544 6.21e-16

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 77.29  E-value: 6.21e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  433 CDFPPAIAHGR-YTKSSSYYVRTQVTYECEEG-----YRLVGEATISCWYS-QWTPAAPQCKAL-CRKPEIGNGVLS--- 501
Cdd:PHA02817  24 CCYPPSIKNGYiYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDgKWNKEFPVCKIIrCRFPALQNGFVNgip 103

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 77539456  502 TNKDQYVETEnVTIQCDSGFVMLGSQSITCSENGTWYPKVPRC 544
Cdd:PHA02817 104 DSKKFYYESE-VSFSCKPGFVLIGTKYSVCGINSSWIPKVPIC 145
PHA02831 PHA02831
EEV host range protein; Provisional
 182-309 2.53e-14

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 73.49  E-value: 2.53e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  182 CGMPPDISNGKHNGREEEFfTYRSSVTYKCDPD----FTLLGNASITCtvVNKTvgvWSPSPPTCERIICPWPKVLHGTI 257
Cdd:PHA02831  78 CKDPVTILNGYIKNKKDQY-SFGDSVTYACKVNklekYSIVGNETVKC--INKQ---WVPKYPVCKLIRCKYPALQNGFL 151

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 77539456  258 NSgFKHTYKYKDSVRFVCQKGFVLRGSGVIHCEADGSWSP-VPVCELNSCTDI 309
Cdd:PHA02831 152 NV-FEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPgIPKCVKDKVHNE 203
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 182-243 2.28e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 64.79  E-value: 2.28e-13
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 77539456 182 CGMPPDISNGKHNGREEEFfTYRSSVTYKCDPDFTLLGNASITCTVvnktVGVWSPSPPTCE 243
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSY-SYGSTVTYSCNEGYTLVGSSTITCTE----NGGWSPPPPTCE 57
PHA02831 PHA02831
EEV host range protein; Provisional
 52-242 6.97e-13

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 69.25  E-value: 6.97e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456   52 VAVFGKcgppPDLPYALPASEMNQTdFESHTTLRYNCRPGYSrassSQSLYCKPlGKWQINIACV-KKSCRNPGDLQNGK 130
Cdd:PHA02831  19 ICVFNK----NDAKYSNVDSYENKV-YEENENLEYKCNNNFD----KVFVTCNN-GSWSTKNMCIgKRNCKDPVTILNGY 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  131 VEVKTD-FLFGSQIEFSCS----EGYILIGSSTSYCeIQGKgvsWSDPLPECVIAKCGMPPdISNGKHNGREEEFFtYRS 205
Cdd:PHA02831  89 IKNKKDqYSFGDSVTYACKvnklEKYSIVGNETVKC-INKQ---WVPKYPVCKLIRCKYPA-LQNGFLNVFEKKFY-YGD 162

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 77539456  206 SVTYKCDPDFTLLGNASITCTVVNktvgVWSPSPPTC 242
Cdd:PHA02831 163 IVNFKCKKGFILLGSSVSTCDINS----IWYPGIPKC 195
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 120-178 4.19e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 61.32  E-value: 4.19e-12
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456 120 CRNPGDLQNGKVEV-KTDFLFGSQIEFSCSEGYILIGSSTSYCEIQGKgvsWSDPLPECV 178
Cdd:cd00033   1 CPPPPVPENGTVTGsKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG---WSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 433-487 6.97e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.55  E-value: 6.97e-12
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 77539456 433 CDFPPAIAHGRYT-KSSSYYVRTQVTYECEEGYRLVGEATISCW-YSQWTPAAPQCK 487
Cdd:cd00033   1 CPPPPVPENGTVTgSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
490-544 2.41e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 59.05  E-value: 2.41e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 77539456   490 CRKPE-IGNGVLSTNKDQYVETENVTIQCDSGFVMLGSQSITCSENGTWYPKVPRC 544
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 433-486 3.82e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 58.69  E-value: 3.82e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 77539456    433 CDFPPAIAHGRYTKSSSYY-VRTQVTYECEEGYRLVGEATISCWYS-QWTPAAPQC 486
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYsYGDTVTYSCDPGYTLIGSSTITCLENgTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 493-545 4.64e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 58.24  E-value: 4.64e-11
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 77539456 493 PEIGNGVLSTNKDQYVETENVTIQCDSGFVMLGSQSITCSENGTWYPKVPRCE 545
Cdd:cd00033   5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 182-242 6.73e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.92  E-value: 6.73e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 77539456    182 CGMPPDISNGKHNGREEEFfTYRSSVTYKCDPDFTLLGNASITCTvvnkTVGVWSPSPPTC 242
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTY-SYGDTVTYSCDPGYTLIGSSTITCL----ENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 120-177 1.23e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.15  E-value: 1.23e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 77539456    120 CRNPGDLQNGKVEV-KTDFLFGSQIEFSCSEGYILIGSSTSYCEIQGKgvsWSDPLPEC 177
Cdd:smart00032   1 CPPPPDIENGTVTSsSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGT---WSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 247-302 2.40e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.32  E-value: 2.40e-10
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 77539456 247 CPWPKVLHGTINSGFKHTYKYKDSVRFVCQKGFVLRGSGVIHCEADGSWSP-VPVCE 302
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPpPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
433-486 4.85e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 55.20  E-value: 4.85e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 77539456   433 CDFPPAIAHGR-YTKSSSYYVRTQVTYECEEGYRLVGEATISCWYS-QWTPAAPQC 486
Cdd:pfam00084   1 CPPPPDIPNGKvSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDgTWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 115-244 1.49e-09

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 59.68  E-value: 1.49e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  115 CVKKSCRNPGDLQNGKVEVKTD-FLFGSQIEFSCSE----GYILIGSSTSYCeIQGKgvSWSDPLPECVIAKCGMPPdIS 189
Cdd:PHA02639  80 CMLKECNDPPSIINGKIYNKREmYKVGDEIYYVCNEhkgvQYSLVGNEKITC-IQDK--SWKPDPPICKMINCRFPA-LQ 155

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 77539456  190 NGKHNG-REEEFFTYRSSVTYKCDPDFTLLGNASITCTvVNKTvgvWSPSPPTCER 244
Cdd:PHA02639 156 NGYINGiPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCN-INAT---WFPSIPTCVR 207
Sushi pfam00084
Sushi repeat (SCR repeat);
182-242 1.93e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.66  E-value: 1.93e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 77539456   182 CGMPPDISNGKHNGREEEFFtYRSSVTYKCDPDFTLLGNASITCTvvnkTVGVWSPSPPTC 242
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYN-YGASVSYECDPGYRLVGSPTITCQ----EDGTWSPPFPEC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 298-544 1.34e-08

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 56.63  E-value: 1.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  298 VPVCELNSCTdIPDIPNAALITSprprkEDVYPVGTVLRYICRPGYEPATRQpmtVICQKDlSWSMLRGCKEICcpvpdp 377
Cdd:PHA02954  13 LPAVVYSTCT-VPTMNNAKLTST-----ETSFNDKQKVTFTCDSGYYSLDPN---AVCETD-KWKYENPCKKMC------ 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  378 ksvrVIQHEKAHPDNDCTYFFGDEVSYTCQNDIMLTATCKSDG--TWHPRTPSCHQSCDfPPAIAHGRYTK-SSSYYVRT 454
Cdd:PHA02954  77 ----TVSDYVSELYDKPLYEVNSTITLICKDETKYFRCEEKNGntSWNDTVTCPNAECQ-PLQLEHGSCQPvKEKYSFGE 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  455 QVTYECEEGYRLVGEATISCWYSQWTpAAPQCKALCRKPEIGNGVLSTNKdqYVETENVTIQCDSGFVMLGSQSITCSEn 534
Cdd:PHA02954 152 HITINCDVGYEVIGASYISCTANSWN-VIPSCQQKCDIPSLSNGLISGST--FSIGGVIHLSCKSGFTLTGSPSSTCID- 227

                        250
                 ....*....|
gi 77539456  535 GTWYPKVPRC 544
Cdd:PHA02954 228 GKWNPVLPIC 237
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 247-301 1.76e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.99  E-value: 1.76e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 77539456    247 CP-WPKVLHGTINSGfKHTYKYKDSVRFVCQKGFVLRGSGVIHCEADGSWSP-VPVC 301
Cdd:smart00032   1 CPpPPDIENGTVTSS-SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPpPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
247-301 2.43e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.58  E-value: 2.43e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 77539456   247 CPWPKVLHGTINSGFKHTYKYKDSVRFVCQKGFVLRGSGVIHCEADGSWSP-VPVC 301
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPpFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 493-544 2.51e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.60  E-value: 2.51e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 77539456    493 PEIGNGVLSTNKDQYVETENVTIQCDSGFVMLGSQSITCSENGTWYPKVPRC 544
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
120-177 6.05e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 49.42  E-value: 6.05e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 77539456   120 CRNPGDLQNGKVEV-KTDFLFGSQIEFSCSEGYILIGSSTSYCEIQGkgvSWSDPLPEC 177
Cdd:pfam00084   1 CPPPPDIPNGKVSAtKNEYNYGASVSYECDPGYRLVGSPTITCQEDG---TWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 247-429 2.20e-07

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 52.74  E-value: 2.20e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  247 CPWPKVLHGTINSGFKHTYKYKDSVRFVCQKGFVLRGSGVIHCEADGS---WS-PVPVCELNSCTDIPDIPNAALITspr 322
Cdd:PHA02639  22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNnaiWSnKAPFCMLKECNDPPSIINGKIYN--- 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  323 prKEDVYPVGTVLRYIC--RPGYEPATRQPMTVICQKDLSWSMLRG-CKEICCPVPDPKSVRViqheKAHPDNDcTYFFG 399
Cdd:PHA02639  99 --KREMYKVGDEIYYVCneHKGVQYSLVGNEKITCIQDKSWKPDPPiCKMINCRFPALQNGYI----NGIPSNK-KFYYK 171

                        170       180       190
                 ....*....|....*....|....*....|....
gi 77539456  400 DEVSYTCQNDIMLT----ATCKSDGTWHPRTPSC 429
Cdd:PHA02639 172 TRVGFSCKSGFDLVgekySTCNINATWFPSIPTC 205
PHA02817 PHA02817
EEV Host range protein; Provisional
 391-486 7.78e-07

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 50.32  E-value: 7.78e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  391 DNDCTYFFGDEVSYTCQNDIM---------LTATCKSDGTWHPRTPSCHQ-SCDFpPAIAHGRYT---KSSSYYVRTQVT 457
Cdd:PHA02817  37 NKKTEYNIGSNVTFFCGNNTRgvrytlvgeKNIICEKDGKWNKEFPVCKIiRCRF-PALQNGFVNgipDSKKFYYESEVS 115

                         90       100       110
                 ....*....|....*....|....*....|
gi 77539456  458 YECEEGYRLVGEATISCWY-SQWTPAAPQC 486
Cdd:PHA02817 116 FSCKPGFVLIGTKYSVCGInSSWIPKVPIC 145
PHA02817 PHA02817
EEV Host range protein; Provisional
 301-429 1.85e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 49.17  E-value: 1.85e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  301 CELNSCTDIPDIPNAALITsprprKEDVYPVGTVLRYIC---RPGYEPATRQPMTVICQKDLSWSM-LRGCKEICCPVPD 376
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYN-----KKTEYNIGSNVTFFCgnnTRGVRYTLVGEKNIICEKDGKWNKeFPVCKIIRCRFPA 93

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 77539456  377 PKSVRViqheKAHPDNDcTYFFGDEVSYTCQNDIMLTAT----CKSDGTWHPRTPSC 429
Cdd:PHA02817  94 LQNGFV----NGIPDSK-KFYYESEVSFSCKPGFVLIGTkysvCGINSSWIPKVPIC 145
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 109-244 2.51e-06

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 49.70  E-value: 2.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  109 WQINIACVKKSCRnPGDLQNGKVE-VKTDFLFGSQIEFSCSEGYILIGSSTSYCEIQgkgvSWsDPLPECViAKCGMpPD 187
Cdd:PHA02954 119 WNDTVTCPNAECQ-PLQLEHGSCQpVKEKYSFGEHITINCDVGYEVIGASYISCTAN----SW-NVIPSCQ-QKCDI-PS 190

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 77539456  188 ISNGKHNGREeefFTYRSSVTYKCDPDFTLLGNASITCtvvnkTVGVWSPSPPTCER 244
Cdd:PHA02954 191 LSNGLISGST---FSIGGVIHLSCKSGFTLTGSPSSTC-----IDGKWNPVLPICVR 239
PHA02831 PHA02831
EEV host range protein; Provisional
 107-178 3.27e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 48.84  E-value: 3.27e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 77539456  107 GKW-QINIACVKKSCRNPGdLQNGKVEV-KTDFLFGSQIEFSCSEGYILIGSSTSYCEIQgkgVSWSDPLPECV 178
Cdd:PHA02831 127 KQWvPKYPVCKLIRCKYPA-LQNGFLNVfEKKFYYGDIVNFKCKKGFILLGSSVSTCDIN---SIWYPGIPKCV 196
PHA02817 PHA02817
EEV Host range protein; Provisional
 490-545 1.49e-05

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 46.47  E-value: 1.49e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 77539456  490 CRKPEIGNGVLSTNKDQYVETENVTIQCDSG-----FVMLGSQSITCSENGTWYPKVPRCE 545
Cdd:PHA02817  25 CYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCK 85
Sushi pfam00084
Sushi repeat (SCR repeat);
306-362 1.53e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.49  E-value: 1.53e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 77539456   306 CTDIPDIPNAALITsprprKEDVYPVGTVLRYICRPGYEPATrqPMTVICQKDLSWS 362
Cdd:pfam00084   1 CPPPPDIPNGKVSA-----TKNEYNYGASVSYECDPGYRLVG--SPTITCQEDGTWS 50
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 306-362 3.78e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 41.68  E-value: 3.78e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 77539456 306 CTDIPDIPNAALITSprprkEDVYPVGTVLRYICRPGYEPatRQPMTVICQKDLSWS 362
Cdd:cd00033   1 CPPPPVPENGTVTGS-----KGSYSYGSTVTYSCNEGYTL--VGSSTITCTENGGWS 50
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 372-429 6.62e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 40.97  E-value: 6.62e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 77539456    372 CPVPDPksvrvIQHEKAHPDNDcTYFFGDEVSYTCQNDIML----TATCKSDGTWHPRTPSC 429
Cdd:smart00032   1 CPPPPD-----IENGTVTSSSG-TYSYGDTVTYSCDPGYTLigssTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 306-362 7.45e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 40.59  E-value: 7.45e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 77539456    306 CTDIPDIPNAALITSPRPrkedvYPVGTVLRYICRPGYEPatRQPMTVICQKDLSWS 362
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT-----YSYGDTVTYSCDPGYTL--IGSSTITCLENGTWS 50
PHA02817 PHA02817
EEV Host range protein; Provisional
 103-178 1.88e-04

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 43.39  E-value: 1.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  103 CKPLGKWQINI-ACVKKSCRNPGdLQNGKVEVKTD---FLFGSQIEFSCSEGYILIGSSTSYCEIQGkgvSWSDPLPECV 178
Cdd:PHA02817  71 CEKDGKWNKEFpVCKIIRCRFPA-LQNGFVNGIPDskkFYYESEVSFSCKPGFVLIGTKYSVCGINS---SWIPKVPICS 146
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 372-547 4.39e-04

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 42.77  E-value: 4.39e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  372 CPVPDPKSVRVIQHEKAHPDNDCTYFFGDEVSYTCQNDimltATCKSDgTWHPRTPsCHQSCDFPPAIAHgRYTKSSsYY 451
Cdd:PHA02954  21 CTVPTMNNAKLTSTETSFNDKQKVTFTCDSGYYSLDPN----AVCETD-KWKYENP-CKKMCTVSDYVSE-LYDKPL-YE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  452 VRTQVTYECEEG---YRLVGEATISCWYSQWTPAAPQCKALcrkpEIGNGVLSTNKDQYVETENVTIQCDSGFVMLGSQS 528
Cdd:PHA02954  93 VNSTITLICKDEtkyFRCEEKNGNTSWNDTVTCPNAECQPL----QLEHGSCQPVKEKYSFGEHITINCDVGYEVIGASY 168

                        170
                 ....*....|....*....
gi 77539456  529 ITCSENGtwYPKVPRCEQE 547
Cdd:PHA02954 169 ISCTANS--WNVIPSCQQK 185
Sushi pfam00084
Sushi repeat (SCR repeat);
372-429 5.71e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 38.25  E-value: 5.71e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 77539456   372 CPVPdpksvRVIQHEKAHPDNDcTYFFGDEVSYTC----QNDIMLTATCKSDGTWHPRTPSC 429
Cdd:pfam00084   1 CPPP-----PDIPNGKVSATKN-EYNYGASVSYECdpgyRLVGSPTITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
58-109 7.23e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 37.86  E-value: 7.23e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 77539456    58 CGPPPDLPYALPASEMNQtdFESHTTLRYNCRPGYsRASSSQSLYCKPLGKW 109
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNE--YNYGASVSYECDPGY-RLVGSPTITCQEDGTW 49
PHA02831 PHA02831
EEV host range protein; Provisional
 443-545 1.24e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 41.13  E-value: 1.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456  443 RYTKSSSYYVRT-----QVTYECEEGYRLVgeaTISCWYSQWTpAAPQC--KALCRKP-EIGNGVLSTNKDQYVETENVT 514
Cdd:PHA02831  28 KYSNVDSYENKVyeeneNLEYKCNNNFDKV---FVTCNNGSWS-TKNMCigKRNCKDPvTILNGYIKNKKDQYSFGDSVT 103

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 77539456  515 IQCD----SGFVMLGSQSITCSeNGTWYPKVPRCE 545
Cdd:PHA02831 104 YACKvnklEKYSIVGNETVKCI-NKQWVPKYPVCK 137
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 58-109 2.00e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 36.67  E-value: 2.00e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|..
gi 77539456  58 CGPPPDLPYALPASEmnQTDFESHTTLRYNCRPGYsRASSSQSLYCKPLGKW 109
Cdd:cd00033   1 CPPPPVPENGTVTGS--KGSYSYGSTVTYSCNEGY-TLVGSSTITCTENGGW 49
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 58-109 2.63e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 36.35  E-value: 2.63e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 77539456     58 CGPPPDLPYALPASEmnQTDFESHTTLRYNCRPGYSRaSSSQSLYCKPLGKW 109
Cdd:smart00032   1 CPPPPDIENGTVTSS--SGTYSYGDTVTYSCDPGYTL-IGSSTITCLENGTW 49
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 78-178 8.98e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 38.53  E-value: 8.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77539456   78 FESHTTLryNCRPGYSRASSSQsLYCKPlGKWQINIACVKKsCRNPgDLQNGKVEVKTdFLFGSQIEFSCSEGYILIGSS 157
Cdd:PHA02954 149 FGEHITI--NCDVGYEVIGASY-ISCTA-NSWNVIPSCQQK-CDIP-SLSNGLISGST-FSIGGVIHLSCKSGFTLTGSP 221

                         90       100
                 ....*....|....*....|.
gi 77539456  158 TSYCeIQGKgvsWSDPLPECV 178
Cdd:PHA02954 222 SSTC-IDGK---WNPVLPICV 238
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 395-429 9.02e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 34.75  E-value: 9.02e-03
                        10        20        30
                ....*....|....*....|....*....|....*....
gi 77539456 395 TYFFGDEVSYTCQNDIML----TATCKSDGTWHPRTPSC 429
Cdd:cd00033  18 SYSYGSTVTYSCNEGYTLvgssTITCTENGGWSPPPPTC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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