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Conserved domains on  [gi|145046230|ref|NP_037013|]
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osteopontin precursor [Rattus norvegicus]

Protein Classification

Osteopontin domain-containing protein( domain architecture ID 10467645)

Osteopontin domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Osteopontin pfam00865
Osteopontin;
22-317 1.79e-103

Osteopontin;


:

Pssm-ID: 459969  Cd Length: 291  Bit Score: 304.48  E-value: 1.79e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230   22 AEFGSSEEKAHYSKHSDAVATWLKPDPSQKQNLLAPQNSVSSEETDDFKQETLPSNSNESHDHMDDDDDDDDDGDhAESE 101
Cdd:pfam00865   2 ADSGSSEEKQLYNKHPDAVATWLKPDPSQKQNLLAPQNAVSSEETDDFKQETLPSKSNESHDHMDDVDDDDDGDH-VDSQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230  102 DSVNSDE---------SDESHHSDESDESFTASTQ----ADVLTPIAPTVDVPDGRGDSLAYGLRSKSRSFPVSDEQYPD 168
Cdd:pfam00865  81 DSVDSDDsdhpddshhSDESHHSDESDELVTDFPTdipaTPVFTPAVPTVDTYDGRGDSVAYGLRSKSKKFHKSEVQYPD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230  169 ATDEDLTSRMKSQESDEAIKVIPVAQRLSVPSDQDSNGKTSHESSQLDEPSVETHSLEQSKEYKQRASHESTEQsdaids 248
Cdd:pfam00865 161 ATEEDLTSHMESEESDDAHKAIPVAQRLNVPSDWDSNGKDSHETSQLDDHSVETHSHEQSKEYKLKANDESSEH------ 234
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 145046230  249 aekpdaidsaerSDAIDSQASSKASLEHQSHEFHSHEDKLVLDPKSKEDDRYLKFRISHELESSSSEVN 317
Cdd:pfam00865 235 ------------SDVIDSQESSKVSQEFHSQEFHSHEDKLVLDPKSEEEDKHLKFRVSHELDSASSEVN 291
 
Name Accession Description Interval E-value
Osteopontin pfam00865
Osteopontin;
22-317 1.79e-103

Osteopontin;


Pssm-ID: 459969  Cd Length: 291  Bit Score: 304.48  E-value: 1.79e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230   22 AEFGSSEEKAHYSKHSDAVATWLKPDPSQKQNLLAPQNSVSSEETDDFKQETLPSNSNESHDHMDDDDDDDDDGDhAESE 101
Cdd:pfam00865   2 ADSGSSEEKQLYNKHPDAVATWLKPDPSQKQNLLAPQNAVSSEETDDFKQETLPSKSNESHDHMDDVDDDDDGDH-VDSQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230  102 DSVNSDE---------SDESHHSDESDESFTASTQ----ADVLTPIAPTVDVPDGRGDSLAYGLRSKSRSFPVSDEQYPD 168
Cdd:pfam00865  81 DSVDSDDsdhpddshhSDESHHSDESDELVTDFPTdipaTPVFTPAVPTVDTYDGRGDSVAYGLRSKSKKFHKSEVQYPD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230  169 ATDEDLTSRMKSQESDEAIKVIPVAQRLSVPSDQDSNGKTSHESSQLDEPSVETHSLEQSKEYKQRASHESTEQsdaids 248
Cdd:pfam00865 161 ATEEDLTSHMESEESDDAHKAIPVAQRLNVPSDWDSNGKDSHETSQLDDHSVETHSHEQSKEYKLKANDESSEH------ 234
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 145046230  249 aekpdaidsaerSDAIDSQASSKASLEHQSHEFHSHEDKLVLDPKSKEDDRYLKFRISHELESSSSEVN 317
Cdd:pfam00865 235 ------------SDVIDSQESSKVSQEFHSQEFHSHEDKLVLDPKSEEEDKHLKFRVSHELDSASSEVN 291
OSTEO smart00017
Osteopontin; Osteopontin is an acidic phosphorylated glycoprotein of about 40 Kd which is ...
17-317 1.78e-95

Osteopontin; Osteopontin is an acidic phosphorylated glycoprotein of about 40 Kd which is abundant in the mineral matrix of bones and which binds tightly to hydroxyapatite. It is suggested that osteopontin might function as a cell attachment factor and could play a key role in the adhesion of osteoclasts to the mineral matrix of bone


Pssm-ID: 214472 [Multi-domain]  Cd Length: 287  Bit Score: 284.19  E-value: 1.78e-95
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230    17 LPVKVAEFGSSEEKAHYSKHSDAVATWLKPDPSQKQNLLAPQNSVSSEETDDFKQETLPSNSNES-------HDHMDDDD 89
Cdd:smart00017   1 LPVKHADSGSSEEKQLYNKHPDAVATWLKPDPSQKQNLLAPQNAVSSEETDDFKQETLPSKSNEShehtddlDDDDDDDH 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230    90 DDDDDGDHAESEDSVNSDESDESHHSDESDE--SFTASTQADVLTPIAPTVDVPDGRGDSLAYGLRSKSRSFPVSDEQYP 167
Cdd:smart00017  81 VDDRDNDSDDAEDSDDSDESDESHHSDESDVtdFPTDAPATDVFTPFVPTVDTNDGRGDSVAYGLRSKSKKFRVSNLQYP 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230   168 DATDEDLTSRMKSQESDEAIKVIPVAQRLSVPSDQDSNGKTSHESSQLDEPSVETHSLEQSKEYkqrashesteqsdaid 247
Cdd:smart00017 161 DATEEDLTSHVESEELDDAPKAIPVAQRLNVPSDWDSAGKDSHKTSQLDDHSVETHSHEQSKEY---------------- 224
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230   248 saeKPDAIDSAERSDAIDSQASSKASlehqSHEFHSHEDKLVLDPKSKEDDRYLKFRISHELESSSSEVN 317
Cdd:smart00017 225 ---KRKAFDSNEHSDVIDSQESSKVS----SREFHSHEDKLDLDPKSEEDDKHLKFRISHELDSASSEVN 287
 
Name Accession Description Interval E-value
Osteopontin pfam00865
Osteopontin;
22-317 1.79e-103

Osteopontin;


Pssm-ID: 459969  Cd Length: 291  Bit Score: 304.48  E-value: 1.79e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230   22 AEFGSSEEKAHYSKHSDAVATWLKPDPSQKQNLLAPQNSVSSEETDDFKQETLPSNSNESHDHMDDDDDDDDDGDhAESE 101
Cdd:pfam00865   2 ADSGSSEEKQLYNKHPDAVATWLKPDPSQKQNLLAPQNAVSSEETDDFKQETLPSKSNESHDHMDDVDDDDDGDH-VDSQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230  102 DSVNSDE---------SDESHHSDESDESFTASTQ----ADVLTPIAPTVDVPDGRGDSLAYGLRSKSRSFPVSDEQYPD 168
Cdd:pfam00865  81 DSVDSDDsdhpddshhSDESHHSDESDELVTDFPTdipaTPVFTPAVPTVDTYDGRGDSVAYGLRSKSKKFHKSEVQYPD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230  169 ATDEDLTSRMKSQESDEAIKVIPVAQRLSVPSDQDSNGKTSHESSQLDEPSVETHSLEQSKEYKQRASHESTEQsdaids 248
Cdd:pfam00865 161 ATEEDLTSHMESEESDDAHKAIPVAQRLNVPSDWDSNGKDSHETSQLDDHSVETHSHEQSKEYKLKANDESSEH------ 234
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 145046230  249 aekpdaidsaerSDAIDSQASSKASLEHQSHEFHSHEDKLVLDPKSKEDDRYLKFRISHELESSSSEVN 317
Cdd:pfam00865 235 ------------SDVIDSQESSKVSQEFHSQEFHSHEDKLVLDPKSEEEDKHLKFRVSHELDSASSEVN 291
OSTEO smart00017
Osteopontin; Osteopontin is an acidic phosphorylated glycoprotein of about 40 Kd which is ...
17-317 1.78e-95

Osteopontin; Osteopontin is an acidic phosphorylated glycoprotein of about 40 Kd which is abundant in the mineral matrix of bones and which binds tightly to hydroxyapatite. It is suggested that osteopontin might function as a cell attachment factor and could play a key role in the adhesion of osteoclasts to the mineral matrix of bone


Pssm-ID: 214472 [Multi-domain]  Cd Length: 287  Bit Score: 284.19  E-value: 1.78e-95
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230    17 LPVKVAEFGSSEEKAHYSKHSDAVATWLKPDPSQKQNLLAPQNSVSSEETDDFKQETLPSNSNES-------HDHMDDDD 89
Cdd:smart00017   1 LPVKHADSGSSEEKQLYNKHPDAVATWLKPDPSQKQNLLAPQNAVSSEETDDFKQETLPSKSNEShehtddlDDDDDDDH 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230    90 DDDDDGDHAESEDSVNSDESDESHHSDESDE--SFTASTQADVLTPIAPTVDVPDGRGDSLAYGLRSKSRSFPVSDEQYP 167
Cdd:smart00017  81 VDDRDNDSDDAEDSDDSDESDESHHSDESDVtdFPTDAPATDVFTPFVPTVDTNDGRGDSVAYGLRSKSKKFRVSNLQYP 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230   168 DATDEDLTSRMKSQESDEAIKVIPVAQRLSVPSDQDSNGKTSHESSQLDEPSVETHSLEQSKEYkqrashesteqsdaid 247
Cdd:smart00017 161 DATEEDLTSHVESEELDDAPKAIPVAQRLNVPSDWDSAGKDSHKTSQLDDHSVETHSHEQSKEY---------------- 224
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145046230   248 saeKPDAIDSAERSDAIDSQASSKASlehqSHEFHSHEDKLVLDPKSKEDDRYLKFRISHELESSSSEVN 317
Cdd:smart00017 225 ---KRKAFDSNEHSDVIDSQESSKVS----SREFHSHEDKLDLDPKSEEDDKHLKFRISHELDSASSEVN 287
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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