View
Concise Results
Standard Results
Full Results
centrosome-associated protein 350 [Homo sapiens]
Protein Classification
List of domain hits
Name
Accession
Description
Interval
E-value
CAP_GLY
pfam01302 CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
2499-2563
3.02e-29
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Pssm-ID: 460154 [Multi-domain]
Cd Length: 65
Bit Score: 112.11
E-value: 3.02e-29
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 171184451 2499 I GDRV LIGNVQP G IL R FK G ETS FA K G F W A GVELD K P E G N N N G TYD G IA YFEC KE KHG I F AP P Q K I 2563
Cdd:pfam01302 1 V GDRV EVPGGRR G TV R YV G PVP FA P G V W V GVELD E P V G K N D G SVK G VR YFEC PP KHG V F VR P S K V 65
NIP100 super family
cl34954 Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
2499-2782
1.69e-15
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];
COG5244 :Pssm-ID: 227569 [Multi-domain]
Cd Length: 669
Bit Score: 83.20
E-value: 1.69e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2499 IG DRVL I G N v QP G IL RF K G E T S F AK G F W A G V ELD K P E G N N N G TYD G IA YF E CK EK HGIF AP P QKI S HIPE N f DD Y VD I NE 2578
Cdd:COG5244 6 VN DRVL L G D - KF G TV RF I G K T K F KD G I W I G L ELD D P V G K N D G SVN G VR YF H CK KR HGIF IR P DDD S LLNG N - AA Y EK I KG 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2579 DED C ysderyq CYNQEQN D T E GPKDREK D VSEYFYE K SLPSVND IEA SVNRSRSLKI E TDNVQD isgvlea HVHQQSSVD 2658
Cdd:COG5244 84 GLV C ------- ESKGMDK D G E IKQENHE D RIHFEES K IRRLEET IEA LKSTEKEEIV E LRRENE ------- ELDKINLSL 149
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2659 SQIS S K E NKD L IS D AT e K V S IAAEDDTLDNTFSE ----- EL EKQQQF T EEEDNLYAEA S EKL C -- TPLL D L L TREKNQ L E 2731
Cdd:COG5244 150 RERI S S E EPE L NK D GS - K L S YDELKEFVEESRVQ vydmv EL VSDISE T LNRNGSIQRS S VRE C er SNIH D V L FLVNGI L D 228
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 171184451 2732 AQLKSSLN E EKKSKQ QL ------ EK I SLLTD S L LK VFVKDTVNQLQQIKKTRD E KI Q 2782
Cdd:COG5244 229 GVIDELNG E LERLRR QL vslmss HG I EVEEN S R LK ATLEKFQSLELKVNTLQE E LY Q 285
PTZ00121 super family
cl31754 MAEBL; Provisional
1341-1964
3.42e-07
MAEBL; Provisional
PTZ00121 :Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 56.69
E-value: 3.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1341 E SV R QLSD V ERVRGISL A QQ esvs LAQIIK A QQQRH ER DLALLKLKAEQEAL E SQRQL EE TRNK A AQVH - AE SLQQVVQS 1419
Cdd:PTZ00121 1179 E AA R KAEE V RKAEELRK A ED ---- ARKAEA A RKAEE ER KAEEARKAEDAKKA E AVKKA EE AKKD A EEAK k AE EERNNEEI 1254
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1420 QREVTEVLQEATCKI AA QQS E T AR l TT D AARQIC E MAELTRTHISDAV -------- V A SG A PL A ILYDHQRQHLPDFVKQ 1491
Cdd:PTZ00121 1255 RKFEEARMAHFARRQ AA IKA E E AR - KA D ELKKAE E KKKADEAKKAEEK kkadeakk K A EE A KK A DEAKKKAEEAKKKADA 1333
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1492 LRTRT E TDR K SPSVSLSQSKEGTLDSKHQKYS A SYDSYSESSGY K NH D RRSSSGSSRQESPSVPSCK E NE KK ---- L NGE 1567
Cdd:PTZ00121 1334 AKKKA E EAK K AAEAAKAEAEAAADEAEAAEEK A EAAEKKKEEAK K KA D AAKKKAEEKKKADEAKKKA E ED KK kade L KKA 1413
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1568 KIESSIDEQVQTA A DDSLRS D SVPSLPD E KDS tsi A T E YSL K FD E SMTED E IEEQSFRSLLPS E SHRRFNME K RRGHHDD 1647
Cdd:PTZ00121 1414 AAAKKKADEAKKK A EEKKKA D EAKKKAE E AKK --- A D E AKK K AE E AKKAE E AKKKAEEAKKAD E AKKKAEEA K KADEAKK 1490
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1648 SD EEA SPEKTTLST A K E LNMPFSGGQDSFSKFTMEMVR qym K E EE MRA A HQSSLLRLRE KA LKE K TKA EL AWL E HQ KK - H 1726
Cdd:PTZ00121 1491 KA EEA KKKADEAKK A A E AKKKADEAKKAEEAKKADEAK --- K A EE AKK A DEAKKAEEKK KA DEL K KAE EL KKA E EK KK a E 1567
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1727 LRD K G E D DK MPP LRK KQ rglllrl QQE KAE IK R LQ E AN K AARK E RQL ilk QQ EE IE K IRQTT IK LQ E KL K SAG E S K LDSH 1806
Cdd:PTZ00121 1568 EAK K A E E DK NMA LRK AE ------- EAK KAE EA R IE E VM K LYEE E KKM --- KA EE AK K AEEAK IK AE E LK K AEE E K K KVEQ 1637
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1807 SDDDTKDN K ATSPGPTDL E TRSPSPISISSSETSSIMQ K LKKMRSRMDEK fl T K REQK L MQRRQH A EELL E W K RR lda E E 1886
Cdd:PTZ00121 1638 LKKKEAEE K KKAEELKKA E EENKIKAAEEAKKAEEDKK K AEEAKKAEEDE -- K K AAEA L KKEAEE A KKAE E L K KK --- E A 1712
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 171184451 1887 A E IRQM E k QALA A WDKEL IK PKTP KKE L E DQRTEQK E IASE EE SPVPL y S HL NS E SSIPE E LGSPAV E Y V PS E SIGQ E 1964
Cdd:PTZ00121 1713 E E KKKA E - ELKK A EEENK IK AEEA KKE A E EDKKKAE E AKKD EE EKKKI - A HL KK E EEKKA E EIRKEK E A V IE E ELDE E 1788
SMC_N super family
cl47134 RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
1688-2478
5.71e-04
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
pfam02463 :Pssm-ID: 481474 [Multi-domain]
Cd Length: 1161
Bit Score: 45.73
E-value: 5.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1688 M KEE E M R AAHQSSLLRL R E K AL K EKTKAE L AWLEHQKKH L RDKG E DD K MPP L R - K K Q RGLL L RLQ Q E K AEIKRLQ E ANKA 1766
Cdd:pfam02463 149 M MKP E R R LEIEEEAAGS R L K RK K KEALKK L IEETENLAE L IIDL E EL K LQE L K l K E Q AKKA L EYY Q L K EKLELEE E YLLY 228
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1767 ARKE ---------- RQ L ILKQ QEEIE KIR Q TTI K LQ EKL K --------- SAGESKLDSHSDDDT K DNKATSPGPTD LE T R 1827
Cdd:pfam02463 229 LDYL klneeridll QE L LRDE QEEIE SSK Q EIE K EE EKL A qvlkenkee EKEKKLQEEELKLLA K EEEELKSELLK LE R R 308
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1828 SPSPI -------- SISSS E TSSIMQ K LKKMRSRMDE K F L TKREQKLMQRRQHA E E L L E WKRR L DA E EAEIRQM E KQA L AA 1899
Cdd:pfam02463 309 KVDDE eklkesek EKKKA E KELKKE K EEIEELEKEL K E L EIKREAEEEEEEEL E K L Q E KLEQ L EE E LLAKKKL E SER L SS 388
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1900 WD K ELIKPKTP K K E L E DQRTEQK E I A SEE E S pv P L YSHLNS E SS I P EE LGSPAVEYVPSESIGQ E qpgspdhs I L TEEMI 1979
Cdd:pfam02463 389 AA K LKEEELEL K S E E E KEAQLLL E L A RQL E D -- L L KEEKKE E LE I L EE EEESIELKQGKLTEEK E -------- E L EKQEL 458
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1980 CSQEL E SSTSP S KHS L PKSCTSVSKQESSKGSH R TGGQCHLPIK S HQHCYSWSDES L SMTQSETTSDQSDIEGRIRALKD 2059
Cdd:pfam02463 459 KLLKD E LELKK S EDL L KETQLVKLQEQLELLLS R QKLEERSQKE S KARSGLKVLLA L IKDGVGGRIISAHGRLGDLGVAV 538
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2060 E LR K RKSVVNQLKKEQK krqkerl K A Q E ASLIKQ L ESYDEFIKKTEAE L SQDLETSPTAKPQ I KT L SSASEKPKIKPL -- 2137
Cdd:pfam02463 539 E NY K VAISTAVIVEVSA ------- T A D E VEERQK L VRALTELPLGARK L RLLIPKLKLPLKS I AV L EIDPILNLAQLD ka 611
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2138 --------- TPLHRSETA K NWKSLTES E RSRGSLESIAEH V DASLSGS E R S VSER SLS AYA K RVN E WDSRT E DFQ --- TP 2205
Cdd:pfam02463 612 tleadeddk RAKVVEGIL K DTELTKLK E SAKAKESGLRKG V SLEEGLA E K S EVKA SLS ELT K ELL E IQELQ E KAE sel AK 691
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2206 SPV LR SSRK I REESGDSL E NVPA L H L LK E LNATS R I - LDMSDGKVGESSK K SE I K E I E y TKLK KS KIEDAFSK E G KS DVL 2284
Cdd:pfam02463 692 EEI LR RQLE I KKKEQREK E ELKK L K L EA E ELLAD R V q EAQDKINEELKLL K QK I D E E E - EEEE KS RLKKEEKE E E KS ELS 770
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2285 LK LVLEQGDSSEILSK K DLPLDS E NVQKDLVG L AIENLHKS EE MLKERQSDQDMNHSPN I QS g KDIH E QKNTKEKDLSWS 2364
Cdd:pfam02463 771 LK EKELAEEREKTEKL K VEEEKE E KLKAQEEE L RALEEELK EE AELLEEEQLLIEQEEK I KE - EELE E LALELKEEQKLE 849
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2365 EHLFAPK E IPYS E DFEVSSFKKEISA E LYKDDFEVSSL L SLRKDSQSCRD K PQPMR S STSGA tsfg SN E EIS E CLSEKSL 2444
Cdd:pfam02463 850 KLAEEEL E RLEE E ITKEELLQELLLK E EELEEQKLKDE L ESKEEKEKEEK K ELEEE S QKLNL ---- LE E KEN E IEERIKE 925
810 820 830
....*....|....*....|....*....|....*
gi 171184451 2445 SIHSNVHSDRLL - EL KSPTELM K S KE RSDV E H E QQ 2478
Cdd:pfam02463 926 EAEILLKYEEEP e EL LLEEADE K E KE ENNK E E E EE 960
Name
Accession
Description
Interval
E-value
CAP_GLY
pfam01302 CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
2499-2563
3.02e-29
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Pssm-ID: 460154 [Multi-domain]
Cd Length: 65
Bit Score: 112.11
E-value: 3.02e-29
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 171184451 2499 I GDRV LIGNVQP G IL R FK G ETS FA K G F W A GVELD K P E G N N N G TYD G IA YFEC KE KHG I F AP P Q K I 2563
Cdd:pfam01302 1 V GDRV EVPGGRR G TV R YV G PVP FA P G V W V GVELD E P V G K N D G SVK G VR YFEC PP KHG V F VR P S K V 65
CAP_GLY
smart01052 Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
2499-2564
3.25e-26
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Pssm-ID: 214997 [Multi-domain]
Cd Length: 68
Bit Score: 103.82
E-value: 3.25e-26
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 171184451 2499 I GDRV LI - G NVQP G IL R FK G E T S FA K G F W A GVELD K P E - G N N N G TYD G IA YFEC KE KHGIF AP P Q K IS 2564
Cdd:smart01052 1 V GDRV EV g G GGRR G TV R YV G P T P FA P G V W V GVELD E P L r G K N D G SVK G VR YFEC PP KHGIF VR P S K VE 68
NIP100
COG5244 Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
2499-2782
1.69e-15
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 227569 [Multi-domain]
Cd Length: 669
Bit Score: 83.20
E-value: 1.69e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2499 IG DRVL I G N v QP G IL RF K G E T S F AK G F W A G V ELD K P E G N N N G TYD G IA YF E CK EK HGIF AP P QKI S HIPE N f DD Y VD I NE 2578
Cdd:COG5244 6 VN DRVL L G D - KF G TV RF I G K T K F KD G I W I G L ELD D P V G K N D G SVN G VR YF H CK KR HGIF IR P DDD S LLNG N - AA Y EK I KG 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2579 DED C ysderyq CYNQEQN D T E GPKDREK D VSEYFYE K SLPSVND IEA SVNRSRSLKI E TDNVQD isgvlea HVHQQSSVD 2658
Cdd:COG5244 84 GLV C ------- ESKGMDK D G E IKQENHE D RIHFEES K IRRLEET IEA LKSTEKEEIV E LRRENE ------- ELDKINLSL 149
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2659 SQIS S K E NKD L IS D AT e K V S IAAEDDTLDNTFSE ----- EL EKQQQF T EEEDNLYAEA S EKL C -- TPLL D L L TREKNQ L E 2731
Cdd:COG5244 150 RERI S S E EPE L NK D GS - K L S YDELKEFVEESRVQ vydmv EL VSDISE T LNRNGSIQRS S VRE C er SNIH D V L FLVNGI L D 228
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 171184451 2732 AQLKSSLN E EKKSKQ QL ------ EK I SLLTD S L LK VFVKDTVNQLQQIKKTRD E KI Q 2782
Cdd:COG5244 229 GVIDELNG E LERLRR QL vslmss HG I EVEEN S R LK ATLEKFQSLELKVNTLQE E LY Q 285
PTZ00121
PTZ00121 MAEBL; Provisional
1341-1964
3.42e-07
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 56.69
E-value: 3.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1341 E SV R QLSD V ERVRGISL A QQ esvs LAQIIK A QQQRH ER DLALLKLKAEQEAL E SQRQL EE TRNK A AQVH - AE SLQQVVQS 1419
Cdd:PTZ00121 1179 E AA R KAEE V RKAEELRK A ED ---- ARKAEA A RKAEE ER KAEEARKAEDAKKA E AVKKA EE AKKD A EEAK k AE EERNNEEI 1254
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1420 QREVTEVLQEATCKI AA QQS E T AR l TT D AARQIC E MAELTRTHISDAV -------- V A SG A PL A ILYDHQRQHLPDFVKQ 1491
Cdd:PTZ00121 1255 RKFEEARMAHFARRQ AA IKA E E AR - KA D ELKKAE E KKKADEAKKAEEK kkadeakk K A EE A KK A DEAKKKAEEAKKKADA 1333
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1492 LRTRT E TDR K SPSVSLSQSKEGTLDSKHQKYS A SYDSYSESSGY K NH D RRSSSGSSRQESPSVPSCK E NE KK ---- L NGE 1567
Cdd:PTZ00121 1334 AKKKA E EAK K AAEAAKAEAEAAADEAEAAEEK A EAAEKKKEEAK K KA D AAKKKAEEKKKADEAKKKA E ED KK kade L KKA 1413
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1568 KIESSIDEQVQTA A DDSLRS D SVPSLPD E KDS tsi A T E YSL K FD E SMTED E IEEQSFRSLLPS E SHRRFNME K RRGHHDD 1647
Cdd:PTZ00121 1414 AAAKKKADEAKKK A EEKKKA D EAKKKAE E AKK --- A D E AKK K AE E AKKAE E AKKKAEEAKKAD E AKKKAEEA K KADEAKK 1490
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1648 SD EEA SPEKTTLST A K E LNMPFSGGQDSFSKFTMEMVR qym K E EE MRA A HQSSLLRLRE KA LKE K TKA EL AWL E HQ KK - H 1726
Cdd:PTZ00121 1491 KA EEA KKKADEAKK A A E AKKKADEAKKAEEAKKADEAK --- K A EE AKK A DEAKKAEEKK KA DEL K KAE EL KKA E EK KK a E 1567
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1727 LRD K G E D DK MPP LRK KQ rglllrl QQE KAE IK R LQ E AN K AARK E RQL ilk QQ EE IE K IRQTT IK LQ E KL K SAG E S K LDSH 1806
Cdd:PTZ00121 1568 EAK K A E E DK NMA LRK AE ------- EAK KAE EA R IE E VM K LYEE E KKM --- KA EE AK K AEEAK IK AE E LK K AEE E K K KVEQ 1637
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1807 SDDDTKDN K ATSPGPTDL E TRSPSPISISSSETSSIMQ K LKKMRSRMDEK fl T K REQK L MQRRQH A EELL E W K RR lda E E 1886
Cdd:PTZ00121 1638 LKKKEAEE K KKAEELKKA E EENKIKAAEEAKKAEEDKK K AEEAKKAEEDE -- K K AAEA L KKEAEE A KKAE E L K KK --- E A 1712
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 171184451 1887 A E IRQM E k QALA A WDKEL IK PKTP KKE L E DQRTEQK E IASE EE SPVPL y S HL NS E SSIPE E LGSPAV E Y V PS E SIGQ E 1964
Cdd:PTZ00121 1713 E E KKKA E - ELKK A EEENK IK AEEA KKE A E EDKKKAE E AKKD EE EKKKI - A HL KK E EEKKA E EIRKEK E A V IE E ELDE E 1788
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1685-1929
4.23e-04
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 46.08
E-value: 4.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1685 R QYMK E E E MRA A HQSS L LRLR E KALK E KTKA E LAWL E HQKKHLRDKG E DDK mpp LRKKQRG LL LR L QQEKAE I K RL Q E AN 1764
Cdd:COG1196 235 R ELEA E L E ELE A ELEE L EAEL E ELEA E LAEL E AELE E LRLELEELEL E LEE --- AQAEEYE LL AE L ARLEQD I A RL E E RR 311
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1765 KAARKERQ lil KQQ EE IEKIRQTTIK L Q E K L KSAG E SKLDSHSDDDTKDNKAT spgpt DL E TRSPSPISISSSETSSIMQ 1844
Cdd:COG1196 312 RELEERLE --- ELE EE LAELEEELEE L E E E L EELE E ELEEAEEELEEAEAELA ----- EA E EALLEAEAELAEAEEELEE 383
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1845 KLKKMRSRMDEKF -------- L TKR E QK L MQ R RQHA EE L LE WKRRLD AE EA E IRQM E KQ AL AAWDK E LIKPKTPKKE L ED 1916
Cdd:COG1196 384 LAEELLEALRAAA elaaqlee L EEA E EA L LE R LERL EE E LE ELEEAL AE LE E EEEE E EE AL EEAAE E EAELEEEEEA L LE 463
250
....*....|...
gi 171184451 1917 QRT E QK E I A SEE E 1929
Cdd:COG1196 464 LLA E LL E E A ALL E 476
SMC_N
pfam02463 RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
1688-2478
5.71e-04
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain]
Cd Length: 1161
Bit Score: 45.73
E-value: 5.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1688 M KEE E M R AAHQSSLLRL R E K AL K EKTKAE L AWLEHQKKH L RDKG E DD K MPP L R - K K Q RGLL L RLQ Q E K AEIKRLQ E ANKA 1766
Cdd:pfam02463 149 M MKP E R R LEIEEEAAGS R L K RK K KEALKK L IEETENLAE L IIDL E EL K LQE L K l K E Q AKKA L EYY Q L K EKLELEE E YLLY 228
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1767 ARKE ---------- RQ L ILKQ QEEIE KIR Q TTI K LQ EKL K --------- SAGESKLDSHSDDDT K DNKATSPGPTD LE T R 1827
Cdd:pfam02463 229 LDYL klneeridll QE L LRDE QEEIE SSK Q EIE K EE EKL A qvlkenkee EKEKKLQEEELKLLA K EEEELKSELLK LE R R 308
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1828 SPSPI -------- SISSS E TSSIMQ K LKKMRSRMDE K F L TKREQKLMQRRQHA E E L L E WKRR L DA E EAEIRQM E KQA L AA 1899
Cdd:pfam02463 309 KVDDE eklkesek EKKKA E KELKKE K EEIEELEKEL K E L EIKREAEEEEEEEL E K L Q E KLEQ L EE E LLAKKKL E SER L SS 388
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1900 WD K ELIKPKTP K K E L E DQRTEQK E I A SEE E S pv P L YSHLNS E SS I P EE LGSPAVEYVPSESIGQ E qpgspdhs I L TEEMI 1979
Cdd:pfam02463 389 AA K LKEEELEL K S E E E KEAQLLL E L A RQL E D -- L L KEEKKE E LE I L EE EEESIELKQGKLTEEK E -------- E L EKQEL 458
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1980 CSQEL E SSTSP S KHS L PKSCTSVSKQESSKGSH R TGGQCHLPIK S HQHCYSWSDES L SMTQSETTSDQSDIEGRIRALKD 2059
Cdd:pfam02463 459 KLLKD E LELKK S EDL L KETQLVKLQEQLELLLS R QKLEERSQKE S KARSGLKVLLA L IKDGVGGRIISAHGRLGDLGVAV 538
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2060 E LR K RKSVVNQLKKEQK krqkerl K A Q E ASLIKQ L ESYDEFIKKTEAE L SQDLETSPTAKPQ I KT L SSASEKPKIKPL -- 2137
Cdd:pfam02463 539 E NY K VAISTAVIVEVSA ------- T A D E VEERQK L VRALTELPLGARK L RLLIPKLKLPLKS I AV L EIDPILNLAQLD ka 611
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2138 --------- TPLHRSETA K NWKSLTES E RSRGSLESIAEH V DASLSGS E R S VSER SLS AYA K RVN E WDSRT E DFQ --- TP 2205
Cdd:pfam02463 612 tleadeddk RAKVVEGIL K DTELTKLK E SAKAKESGLRKG V SLEEGLA E K S EVKA SLS ELT K ELL E IQELQ E KAE sel AK 691
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2206 SPV LR SSRK I REESGDSL E NVPA L H L LK E LNATS R I - LDMSDGKVGESSK K SE I K E I E y TKLK KS KIEDAFSK E G KS DVL 2284
Cdd:pfam02463 692 EEI LR RQLE I KKKEQREK E ELKK L K L EA E ELLAD R V q EAQDKINEELKLL K QK I D E E E - EEEE KS RLKKEEKE E E KS ELS 770
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2285 LK LVLEQGDSSEILSK K DLPLDS E NVQKDLVG L AIENLHKS EE MLKERQSDQDMNHSPN I QS g KDIH E QKNTKEKDLSWS 2364
Cdd:pfam02463 771 LK EKELAEEREKTEKL K VEEEKE E KLKAQEEE L RALEEELK EE AELLEEEQLLIEQEEK I KE - EELE E LALELKEEQKLE 849
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2365 EHLFAPK E IPYS E DFEVSSFKKEISA E LYKDDFEVSSL L SLRKDSQSCRD K PQPMR S STSGA tsfg SN E EIS E CLSEKSL 2444
Cdd:pfam02463 850 KLAEEEL E RLEE E ITKEELLQELLLK E EELEEQKLKDE L ESKEEKEKEEK K ELEEE S QKLNL ---- LE E KEN E IEERIKE 925
810 820 830
....*....|....*....|....*....|....*
gi 171184451 2445 SIHSNVHSDRLL - EL KSPTELM K S KE RSDV E H E QQ 2478
Cdd:pfam02463 926 EAEILLKYEEEP e EL LLEEADE K E KE ENNK E E E EE 960
PTZ00121
PTZ00121 MAEBL; Provisional
1682-2347
2.36e-03
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 43.98
E-value: 2.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1682 E MV R QY mk E EEMR A AH qssl LRLR E K A L K EKTK A EL A WL E HQKKHL R d K G E DDK M PPLRKK Q RGLLLRLQQEKA E I K RLQ 1761
Cdd:PTZ00121 1215 E EA R KA -- E DAKK A EA ---- VKKA E E A K K DAEE A KK A EE E RNNEEI R - K F E EAR M AHFARR Q AAIKAEEARKAD E L K KAE 1287
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1762 E AN KA ARKERQLIL K QQE E IE K IRQTTI K LQ E KL K S A G E S K ldshsdddtkd N KA TSPGPTDL E TRSPSPISISSS E TSS 1841
Cdd:PTZ00121 1288 E KK KA DEAKKAEEK K KAD E AK K KAEEAK K AD E AK K K A E E A K ----------- K KA DAAKKKAE E AKKAAEAAKAEA E AAA 1356
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1842 IMQKLKKMRSRMD EK FLTKREQ K LMQRRQH AEE llew K RRL D AEEAEIRQME K Q A laawd K EL I K PKTP KK ELEDQRTEQ 1921
Cdd:PTZ00121 1357 DEAEAAEEKAEAA EK KKEEAKK K ADAAKKK AEE ---- K KKA D EAKKKAEEDK K K A ----- D EL K K AAAA KK KADEAKKKA 1427
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1922 K E IASEE E S pvply SHLNS E SSIPE E LGSP A V E YVPS E SI --- GQ E QPGSPDHSILT EE MICSQ E LESSTSPS K hslp K S 1998
Cdd:PTZ00121 1428 E E KKKAD E A ----- KKKAE E AKKAD E AKKK A E E AKKA E EA kkk AE E AKKADEAKKKA EE AKKAD E AKKKAEEA K ---- K K 1498
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1999 CTSVS K QESS K GS hrtggqchlpikshqhcysw S DE SLSMTQSETTSDQSDI E GRIR A lk DE LR K RKSV vnqlkkeqkkr 2078
Cdd:PTZ00121 1499 ADEAK K AAEA K KK -------------------- A DE AKKAEEAKKADEAKKA E EAKK A -- DE AK K AEEK ----------- 1545
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2079 qker L KA Q E ASLIKQ L ESYD E FI K KT EA ELSQDLETSPTA K PQI ktl SSAS E KPK I KPLTP L HRS E TAKNWKSLTES E RS 2158
Cdd:PTZ00121 1546 ---- K KA D E LKKAEE L KKAE E KK K AE EA KKAEEDKNMALR K AEE --- AKKA E EAR I EEVMK L YEE E KKMKAEEAKKA E EA 1618
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2159 RGSL E SI -- AE HVDASLSGSERSVS E RSLS A YAKRVN E WDSRTEDFQTPSPVLRSSR K IR E ESGDSLENVP A LHL LK ELN 2236
Cdd:PTZ00121 1619 KIKA E EL kk AE EEKKKVEQLKKKEA E EKKK A EELKKA E EENKIKAAEEAKKAEEDKK K AE E AKKAEEDEKK A AEA LK KEA 1698
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2237 ATSRILDMSDG K VG E SS KK S E -- I K EI E YT K L K KSKIEDAFSKEG K SDVLL K lv LEQGDSSE I LS - KK DLPLDS E NVQ K D 2313
Cdd:PTZ00121 1699 EEAKKAEELKK K EA E EK KK A E el K K AE E EN K I K AEEAKKEAEEDK K KAEEA K -- KDEEEKKK I AH l KK EEEKKA E EIR K E 1776
650 660 670
....*....|....*....|....*....|....*..
gi 171184451 2314 LVGLAI E N L HKSE E --- M LKERQSDQDMNHSP NI QS G 2347
Cdd:PTZ00121 1777 KEAVIE E E L DEED E krr M EVDKKIKDIFDNFA NI IE G 1813
Name
Accession
Description
Interval
E-value
CAP_GLY
pfam01302 CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
2499-2563
3.02e-29
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Pssm-ID: 460154 [Multi-domain]
Cd Length: 65
Bit Score: 112.11
E-value: 3.02e-29
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 171184451 2499 I GDRV LIGNVQP G IL R FK G ETS FA K G F W A GVELD K P E G N N N G TYD G IA YFEC KE KHG I F AP P Q K I 2563
Cdd:pfam01302 1 V GDRV EVPGGRR G TV R YV G PVP FA P G V W V GVELD E P V G K N D G SVK G VR YFEC PP KHG V F VR P S K V 65
CAP_GLY
smart01052 Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
2499-2564
3.25e-26
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Pssm-ID: 214997 [Multi-domain]
Cd Length: 68
Bit Score: 103.82
E-value: 3.25e-26
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 171184451 2499 I GDRV LI - G NVQP G IL R FK G E T S FA K G F W A GVELD K P E - G N N N G TYD G IA YFEC KE KHGIF AP P Q K IS 2564
Cdd:smart01052 1 V GDRV EV g G GGRR G TV R YV G P T P FA P G V W V GVELD E P L r G K N D G SVK G VR YFEC PP KHGIF VR P S K VE 68
NIP100
COG5244 Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
2499-2782
1.69e-15
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 227569 [Multi-domain]
Cd Length: 669
Bit Score: 83.20
E-value: 1.69e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2499 IG DRVL I G N v QP G IL RF K G E T S F AK G F W A G V ELD K P E G N N N G TYD G IA YF E CK EK HGIF AP P QKI S HIPE N f DD Y VD I NE 2578
Cdd:COG5244 6 VN DRVL L G D - KF G TV RF I G K T K F KD G I W I G L ELD D P V G K N D G SVN G VR YF H CK KR HGIF IR P DDD S LLNG N - AA Y EK I KG 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2579 DED C ysderyq CYNQEQN D T E GPKDREK D VSEYFYE K SLPSVND IEA SVNRSRSLKI E TDNVQD isgvlea HVHQQSSVD 2658
Cdd:COG5244 84 GLV C ------- ESKGMDK D G E IKQENHE D RIHFEES K IRRLEET IEA LKSTEKEEIV E LRRENE ------- ELDKINLSL 149
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2659 SQIS S K E NKD L IS D AT e K V S IAAEDDTLDNTFSE ----- EL EKQQQF T EEEDNLYAEA S EKL C -- TPLL D L L TREKNQ L E 2731
Cdd:COG5244 150 RERI S S E EPE L NK D GS - K L S YDELKEFVEESRVQ vydmv EL VSDISE T LNRNGSIQRS S VRE C er SNIH D V L FLVNGI L D 228
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 171184451 2732 AQLKSSLN E EKKSKQ QL ------ EK I SLLTD S L LK VFVKDTVNQLQQIKKTRD E KI Q 2782
Cdd:COG5244 229 GVIDELNG E LERLRR QL vslmss HG I EVEEN S R LK ATLEKFQSLELKVNTLQE E LY Q 285
PTZ00121
PTZ00121 MAEBL; Provisional
1341-1964
3.42e-07
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 56.69
E-value: 3.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1341 E SV R QLSD V ERVRGISL A QQ esvs LAQIIK A QQQRH ER DLALLKLKAEQEAL E SQRQL EE TRNK A AQVH - AE SLQQVVQS 1419
Cdd:PTZ00121 1179 E AA R KAEE V RKAEELRK A ED ---- ARKAEA A RKAEE ER KAEEARKAEDAKKA E AVKKA EE AKKD A EEAK k AE EERNNEEI 1254
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1420 QREVTEVLQEATCKI AA QQS E T AR l TT D AARQIC E MAELTRTHISDAV -------- V A SG A PL A ILYDHQRQHLPDFVKQ 1491
Cdd:PTZ00121 1255 RKFEEARMAHFARRQ AA IKA E E AR - KA D ELKKAE E KKKADEAKKAEEK kkadeakk K A EE A KK A DEAKKKAEEAKKKADA 1333
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1492 LRTRT E TDR K SPSVSLSQSKEGTLDSKHQKYS A SYDSYSESSGY K NH D RRSSSGSSRQESPSVPSCK E NE KK ---- L NGE 1567
Cdd:PTZ00121 1334 AKKKA E EAK K AAEAAKAEAEAAADEAEAAEEK A EAAEKKKEEAK K KA D AAKKKAEEKKKADEAKKKA E ED KK kade L KKA 1413
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1568 KIESSIDEQVQTA A DDSLRS D SVPSLPD E KDS tsi A T E YSL K FD E SMTED E IEEQSFRSLLPS E SHRRFNME K RRGHHDD 1647
Cdd:PTZ00121 1414 AAAKKKADEAKKK A EEKKKA D EAKKKAE E AKK --- A D E AKK K AE E AKKAE E AKKKAEEAKKAD E AKKKAEEA K KADEAKK 1490
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1648 SD EEA SPEKTTLST A K E LNMPFSGGQDSFSKFTMEMVR qym K E EE MRA A HQSSLLRLRE KA LKE K TKA EL AWL E HQ KK - H 1726
Cdd:PTZ00121 1491 KA EEA KKKADEAKK A A E AKKKADEAKKAEEAKKADEAK --- K A EE AKK A DEAKKAEEKK KA DEL K KAE EL KKA E EK KK a E 1567
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1727 LRD K G E D DK MPP LRK KQ rglllrl QQE KAE IK R LQ E AN K AARK E RQL ilk QQ EE IE K IRQTT IK LQ E KL K SAG E S K LDSH 1806
Cdd:PTZ00121 1568 EAK K A E E DK NMA LRK AE ------- EAK KAE EA R IE E VM K LYEE E KKM --- KA EE AK K AEEAK IK AE E LK K AEE E K K KVEQ 1637
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1807 SDDDTKDN K ATSPGPTDL E TRSPSPISISSSETSSIMQ K LKKMRSRMDEK fl T K REQK L MQRRQH A EELL E W K RR lda E E 1886
Cdd:PTZ00121 1638 LKKKEAEE K KKAEELKKA E EENKIKAAEEAKKAEEDKK K AEEAKKAEEDE -- K K AAEA L KKEAEE A KKAE E L K KK --- E A 1712
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 171184451 1887 A E IRQM E k QALA A WDKEL IK PKTP KKE L E DQRTEQK E IASE EE SPVPL y S HL NS E SSIPE E LGSPAV E Y V PS E SIGQ E 1964
Cdd:PTZ00121 1713 E E KKKA E - ELKK A EEENK IK AEEA KKE A E EDKKKAE E AKKD EE EKKKI - A HL KK E EEKKA E EIRKEK E A V IE E ELDE E 1788
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1685-1929
4.23e-04
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 46.08
E-value: 4.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1685 R QYMK E E E MRA A HQSS L LRLR E KALK E KTKA E LAWL E HQKKHLRDKG E DDK mpp LRKKQRG LL LR L QQEKAE I K RL Q E AN 1764
Cdd:COG1196 235 R ELEA E L E ELE A ELEE L EAEL E ELEA E LAEL E AELE E LRLELEELEL E LEE --- AQAEEYE LL AE L ARLEQD I A RL E E RR 311
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1765 KAARKERQ lil KQQ EE IEKIRQTTIK L Q E K L KSAG E SKLDSHSDDDTKDNKAT spgpt DL E TRSPSPISISSSETSSIMQ 1844
Cdd:COG1196 312 RELEERLE --- ELE EE LAELEEELEE L E E E L EELE E ELEEAEEELEEAEAELA ----- EA E EALLEAEAELAEAEEELEE 383
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1845 KLKKMRSRMDEKF -------- L TKR E QK L MQ R RQHA EE L LE WKRRLD AE EA E IRQM E KQ AL AAWDK E LIKPKTPKKE L ED 1916
Cdd:COG1196 384 LAEELLEALRAAA elaaqlee L EEA E EA L LE R LERL EE E LE ELEEAL AE LE E EEEE E EE AL EEAAE E EAELEEEEEA L LE 463
250
....*....|...
gi 171184451 1917 QRT E QK E I A SEE E 1929
Cdd:COG1196 464 LLA E LL E E A ALL E 476
SMC_N
pfam02463 RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
1688-2478
5.71e-04
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain]
Cd Length: 1161
Bit Score: 45.73
E-value: 5.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1688 M KEE E M R AAHQSSLLRL R E K AL K EKTKAE L AWLEHQKKH L RDKG E DD K MPP L R - K K Q RGLL L RLQ Q E K AEIKRLQ E ANKA 1766
Cdd:pfam02463 149 M MKP E R R LEIEEEAAGS R L K RK K KEALKK L IEETENLAE L IIDL E EL K LQE L K l K E Q AKKA L EYY Q L K EKLELEE E YLLY 228
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1767 ARKE ---------- RQ L ILKQ QEEIE KIR Q TTI K LQ EKL K --------- SAGESKLDSHSDDDT K DNKATSPGPTD LE T R 1827
Cdd:pfam02463 229 LDYL klneeridll QE L LRDE QEEIE SSK Q EIE K EE EKL A qvlkenkee EKEKKLQEEELKLLA K EEEELKSELLK LE R R 308
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1828 SPSPI -------- SISSS E TSSIMQ K LKKMRSRMDE K F L TKREQKLMQRRQHA E E L L E WKRR L DA E EAEIRQM E KQA L AA 1899
Cdd:pfam02463 309 KVDDE eklkesek EKKKA E KELKKE K EEIEELEKEL K E L EIKREAEEEEEEEL E K L Q E KLEQ L EE E LLAKKKL E SER L SS 388
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1900 WD K ELIKPKTP K K E L E DQRTEQK E I A SEE E S pv P L YSHLNS E SS I P EE LGSPAVEYVPSESIGQ E qpgspdhs I L TEEMI 1979
Cdd:pfam02463 389 AA K LKEEELEL K S E E E KEAQLLL E L A RQL E D -- L L KEEKKE E LE I L EE EEESIELKQGKLTEEK E -------- E L EKQEL 458
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1980 CSQEL E SSTSP S KHS L PKSCTSVSKQESSKGSH R TGGQCHLPIK S HQHCYSWSDES L SMTQSETTSDQSDIEGRIRALKD 2059
Cdd:pfam02463 459 KLLKD E LELKK S EDL L KETQLVKLQEQLELLLS R QKLEERSQKE S KARSGLKVLLA L IKDGVGGRIISAHGRLGDLGVAV 538
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2060 E LR K RKSVVNQLKKEQK krqkerl K A Q E ASLIKQ L ESYDEFIKKTEAE L SQDLETSPTAKPQ I KT L SSASEKPKIKPL -- 2137
Cdd:pfam02463 539 E NY K VAISTAVIVEVSA ------- T A D E VEERQK L VRALTELPLGARK L RLLIPKLKLPLKS I AV L EIDPILNLAQLD ka 611
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2138 --------- TPLHRSETA K NWKSLTES E RSRGSLESIAEH V DASLSGS E R S VSER SLS AYA K RVN E WDSRT E DFQ --- TP 2205
Cdd:pfam02463 612 tleadeddk RAKVVEGIL K DTELTKLK E SAKAKESGLRKG V SLEEGLA E K S EVKA SLS ELT K ELL E IQELQ E KAE sel AK 691
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2206 SPV LR SSRK I REESGDSL E NVPA L H L LK E LNATS R I - LDMSDGKVGESSK K SE I K E I E y TKLK KS KIEDAFSK E G KS DVL 2284
Cdd:pfam02463 692 EEI LR RQLE I KKKEQREK E ELKK L K L EA E ELLAD R V q EAQDKINEELKLL K QK I D E E E - EEEE KS RLKKEEKE E E KS ELS 770
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2285 LK LVLEQGDSSEILSK K DLPLDS E NVQKDLVG L AIENLHKS EE MLKERQSDQDMNHSPN I QS g KDIH E QKNTKEKDLSWS 2364
Cdd:pfam02463 771 LK EKELAEEREKTEKL K VEEEKE E KLKAQEEE L RALEEELK EE AELLEEEQLLIEQEEK I KE - EELE E LALELKEEQKLE 849
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2365 EHLFAPK E IPYS E DFEVSSFKKEISA E LYKDDFEVSSL L SLRKDSQSCRD K PQPMR S STSGA tsfg SN E EIS E CLSEKSL 2444
Cdd:pfam02463 850 KLAEEEL E RLEE E ITKEELLQELLLK E EELEEQKLKDE L ESKEEKEKEEK K ELEEE S QKLNL ---- LE E KEN E IEERIKE 925
810 820 830
....*....|....*....|....*....|....*
gi 171184451 2445 SIHSNVHSDRLL - EL KSPTELM K S KE RSDV E H E QQ 2478
Cdd:pfam02463 926 EAEILLKYEEEP e EL LLEEADE K E KE ENNK E E E EE 960
PTZ00121
PTZ00121 MAEBL; Provisional
1682-2347
2.36e-03
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 43.98
E-value: 2.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1682 E MV R QY mk E EEMR A AH qssl LRLR E K A L K EKTK A EL A WL E HQKKHL R d K G E DDK M PPLRKK Q RGLLLRLQQEKA E I K RLQ 1761
Cdd:PTZ00121 1215 E EA R KA -- E DAKK A EA ---- VKKA E E A K K DAEE A KK A EE E RNNEEI R - K F E EAR M AHFARR Q AAIKAEEARKAD E L K KAE 1287
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1762 E AN KA ARKERQLIL K QQE E IE K IRQTTI K LQ E KL K S A G E S K ldshsdddtkd N KA TSPGPTDL E TRSPSPISISSS E TSS 1841
Cdd:PTZ00121 1288 E KK KA DEAKKAEEK K KAD E AK K KAEEAK K AD E AK K K A E E A K ----------- K KA DAAKKKAE E AKKAAEAAKAEA E AAA 1356
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1842 IMQKLKKMRSRMD EK FLTKREQ K LMQRRQH AEE llew K RRL D AEEAEIRQME K Q A laawd K EL I K PKTP KK ELEDQRTEQ 1921
Cdd:PTZ00121 1357 DEAEAAEEKAEAA EK KKEEAKK K ADAAKKK AEE ---- K KKA D EAKKKAEEDK K K A ----- D EL K K AAAA KK KADEAKKKA 1427
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1922 K E IASEE E S pvply SHLNS E SSIPE E LGSP A V E YVPS E SI --- GQ E QPGSPDHSILT EE MICSQ E LESSTSPS K hslp K S 1998
Cdd:PTZ00121 1428 E E KKKAD E A ----- KKKAE E AKKAD E AKKK A E E AKKA E EA kkk AE E AKKADEAKKKA EE AKKAD E AKKKAEEA K ---- K K 1498
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1999 CTSVS K QESS K GS hrtggqchlpikshqhcysw S DE SLSMTQSETTSDQSDI E GRIR A lk DE LR K RKSV vnqlkkeqkkr 2078
Cdd:PTZ00121 1499 ADEAK K AAEA K KK -------------------- A DE AKKAEEAKKADEAKKA E EAKK A -- DE AK K AEEK ----------- 1545
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2079 qker L KA Q E ASLIKQ L ESYD E FI K KT EA ELSQDLETSPTA K PQI ktl SSAS E KPK I KPLTP L HRS E TAKNWKSLTES E RS 2158
Cdd:PTZ00121 1546 ---- K KA D E LKKAEE L KKAE E KK K AE EA KKAEEDKNMALR K AEE --- AKKA E EAR I EEVMK L YEE E KKMKAEEAKKA E EA 1618
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2159 RGSL E SI -- AE HVDASLSGSERSVS E RSLS A YAKRVN E WDSRTEDFQTPSPVLRSSR K IR E ESGDSLENVP A LHL LK ELN 2236
Cdd:PTZ00121 1619 KIKA E EL kk AE EEKKKVEQLKKKEA E EKKK A EELKKA E EENKIKAAEEAKKAEEDKK K AE E AKKAEEDEKK A AEA LK KEA 1698
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 2237 ATSRILDMSDG K VG E SS KK S E -- I K EI E YT K L K KSKIEDAFSKEG K SDVLL K lv LEQGDSSE I LS - KK DLPLDS E NVQ K D 2313
Cdd:PTZ00121 1699 EEAKKAEELKK K EA E EK KK A E el K K AE E EN K I K AEEAKKEAEEDK K KAEEA K -- KDEEEKKK I AH l KK EEEKKA E EIR K E 1776
650 660 670
....*....|....*....|....*....|....*..
gi 171184451 2314 LVGLAI E N L HKSE E --- M LKERQSDQDMNHSP NI QS G 2347
Cdd:PTZ00121 1777 KEAVIE E E L DEED E krr M EVDKKIKDIFDNFA NI IE G 1813
PRK12704
PRK12704 phosphodiesterase; Provisional
1682-1784
2.80e-03
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain]
Cd Length: 520
Bit Score: 43.23
E-value: 2.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1682 E MVRQYMK E EEMR A AH -- QSS LL RLR E KAL K EKTKA E ------ LAW L EHQK K H L RD K G E -- D D K MPP L R K KQR glll R L Q 1751
Cdd:PRK12704 38 E EAKRILE E AKKE A EA ik KEA LL EAK E EIH K LRNEF E kelrer RNE L QKLE K R L LQ K E E nl D R K LEL L E K REE ---- E L E 113
90 100 110
....*....|....*....|....*....|....
gi 171184451 1752 QEKA E IKRL Q EANKAARK E - RQ LI LK Q QE E I E K I 1784
Cdd:PRK12704 114 KKEK E LEQK Q QELEKKEE E l EE LI EE Q LQ E L E R I 147
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1331-1804
3.05e-03
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 43.39
E-value: 3.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1331 AEL SY L NAIEESVRQLSDVERV R GIS L AQQESVSLAQIIKAQQQRH E RDLA L LKLKA E Q E AL E sq RQ L E E TRNKAAQVH A 1410
Cdd:COG1196 295 AEL AR L EQDIARLEERRRELEE R LEE L EEELAELEEELEELEEELE E LEEE L EEAEE E L E EA E -- AE L A E AEEALLEAE A 372
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1411 E SLQQVVQSQREVT E V L QEAT c KI A AQQSETAR L TTDAARQICEMAE L TRTHISDA vv ASG A P L AILYDHQRQH L pdf VK 1490
Cdd:COG1196 373 E LAEAEEELEELAE E L L EALR - AA A ELAAQLEE L EEAEEALLERLER L EEELEELE -- EAL A E L EEEEEEEEEA L --- EE 446
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1491 QLRTRT E TDRKSPSVSLSQSKEGTLDSKHQKYS A SYDSYSESSGYKNHDRRSSSGSSRQESPS V PSCKENEKKLNGEK -- 1568
Cdd:COG1196 447 AAEEEA E LEEEEEALLELLAELLEEAALLEAAL A ELLEELAEAAARLLLLLEAEADYEGFLEG V KAALLLAGLRGLAG av 526
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1569 - IESSIDEQVQT A ADDS L RSDSVPSLPDEKDSTSI A T EY SLKFDES - M T EDEIEEQSF R SL L PSESH R RFNMEKRRGHHD 1646
Cdd:COG1196 527 a VLIGVEAAYEA A LEAA L AAALQNIVVEDDEVAAA A I EY LKAAKAG r A T FLPLDKIRA R AA L AAALA R GAIGAAVDLVAS 606
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1647 D SD E EASPEKTTLS T AKELNMPFSGGQDSFSKFTMEMV R QYMKEE E MRAAHQS - SL LRLREKA L KEKTKAEL A W LE HQKK 1725
Cdd:COG1196 607 D LR E ADARYYVLGD T LLGRTLVAARLEAALRRAVTLAG R LREVTL E GEGGSAG g SL TGGSRRE L LAALLEAE A E LE ELAE 686
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 171184451 1726 H L RDKGEDDK mppl RKKQRGLLLRLQQEK AE IK RL Q E ANKAARK E R QL ILKQQ E EI E KIRQTTIK L Q E KLKSAGESKL D 1804
Cdd:COG1196 687 R L AEEELELE ---- EALLAEEEEERELAE AE EE RL E E ELEEEAL E E QL EAERE E LL E ELLEEEEL L E E EALEELPEPP D 761
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1685-1930
9.93e-03
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 41.85
E-value: 9.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1685 RQ Y M -- KEE EMRAAHQSS LL R LRE K alkekt K AEL AW LE HQKKH L RDKG E D dkmpp L RKKQRG L LLR L QQEKA E IKR L QE 1762
Cdd:COG1196 213 ER Y R el KEE LKELEAELL LL K LRE L ------ E AEL EE LE AELEE L EAEL E E ----- L EAELAE L EAE L EELRL E LEE L EL 281
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1763 ANKA A RK E RQLI L KQQEEI E KIRQ tti K L Q E KLKSAG E SK ldshsdddtkdnkatspgptdletrspspisisssetssi 1842
Cdd:COG1196 282 ELEE A QA E EYEL L AELARL E QDIA --- R L E E RRRELE E RL ---------------------------------------- 318
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171184451 1843 mqklkkmrsrmd E KFLTKREQKLMQRRQHA EEL L E WKRR L DAE E A E IRQM E KQALA A wdkelikpktp KKE L EDQRT E QK 1922
Cdd:COG1196 319 ------------ E ELEEELAELEEELEELE EEL E E LEEE L EEA E E E LEEA E AELAE A ----------- EEA L LEAEA E LA 375
....*...
gi 171184451 1923 E IAS E E E S 1930
Cdd:COG1196 376 E AEE E L E E 383
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
