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Conserved domains on  [gi|16506820|ref|NP_055916|]
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procollagen galactosyltransferase 2 isoform 1precursor [Homo sapiens]

Protein Classification

glycosyltransferase family 2 protein( domain architecture ID 10953825)

glycosyltransferase family 2 protein catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glyco_transf_25 pfam01755
Glycosyltransferase family 25 (LPS biosynthesis protein); Members of this family belong to ...
 341-526 8.77e-43

Glycosyltransferase family 25 (LPS biosynthesis protein); Members of this family belong to Glycosyltransferase family 25 This is a family of glycosyltransferases involved in lipopolysaccharide (LPS) biosynthesis. These enzymes catalyze the transfer of various sugars onto the growing LPS chain during its biosynthesis.


:

Pssm-ID: 366794  Cd Length: 200  Bit Score: 152.59  E-value: 8.77e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820   341 FDEIFMINLKRRKDRRDRMLRTLYEQEIEVKIVEAVDGKALNTsqlKALNIEMLPGYRDPYSSRPLTRGEIGCFLSHYSV 420
Cdd:pfam01755   1 MIKIYVISLKRATERREHIQKEFGKLNIPFQFFDAIDGKELPN---HLLFKLYNFLLRSKYAGRPLTLGEIGCFLSHYSL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820   421 WKEVIDRELEKTLVIEDDVRFEHQFKKKLMKLMDNIdqaQLDWELIYIGRKRMQVKEPEKAVPNVANLVEADYSY----- 495
Cdd:pfam01755  78 WQKCVELNLEYIIILEDDVILSENFKAILQFLLKEI---NELEFLRLGEWLKTRFDPNDKFIVRLETFLMDSKKFkrtpi 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 16506820   496 ----------------WTLGYVISLEGAQKLVGANPFGKMlPVDEFL 526
Cdd:pfam01755 155 adygnrafyllksghaGTAGYLITPKAAKKLLKYSKNWPL-PVDDLM 200
Glyco_tranf_GTA_type super family cl11394
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 62-175 5.96e-07

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


The actual alignment was detected with superfamily member pfam13704:

Pssm-ID: 472172 [Multi-domain]  Cd Length: 97  Bit Score: 48.01  E-value: 5.96e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820    62 RNAAHTLPHFLGCLERLDYPksrmAIWAATDHNVDNTTEIFREWlKNVQRLYHyvewrpmdepesypdeigPKHWPTSRF 141
Cdd:pfam13704   1 RNEADILPQWLAHHLALGFD----HIYVYDNGSDDGTAEILARL-PDVSILRS------------------DLSYKDARF 57

                          90       100       110
                  ....*....|....*....|....*....|....
gi 16506820   142 AHVMklRQAALRTAreKWSDYILFIDVDNFLTNP 175
Cdd:pfam13704  58 QVDW--RNALLARY--AEADWVLVVDADEFLVYP 87
 
Name Accession Description Interval E-value
Glyco_transf_25 pfam01755
Glycosyltransferase family 25 (LPS biosynthesis protein); Members of this family belong to ...
 341-526 8.77e-43

Glycosyltransferase family 25 (LPS biosynthesis protein); Members of this family belong to Glycosyltransferase family 25 This is a family of glycosyltransferases involved in lipopolysaccharide (LPS) biosynthesis. These enzymes catalyze the transfer of various sugars onto the growing LPS chain during its biosynthesis.


Pssm-ID: 366794  Cd Length: 200  Bit Score: 152.59  E-value: 8.77e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820   341 FDEIFMINLKRRKDRRDRMLRTLYEQEIEVKIVEAVDGKALNTsqlKALNIEMLPGYRDPYSSRPLTRGEIGCFLSHYSV 420
Cdd:pfam01755   1 MIKIYVISLKRATERREHIQKEFGKLNIPFQFFDAIDGKELPN---HLLFKLYNFLLRSKYAGRPLTLGEIGCFLSHYSL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820   421 WKEVIDRELEKTLVIEDDVRFEHQFKKKLMKLMDNIdqaQLDWELIYIGRKRMQVKEPEKAVPNVANLVEADYSY----- 495
Cdd:pfam01755  78 WQKCVELNLEYIIILEDDVILSENFKAILQFLLKEI---NELEFLRLGEWLKTRFDPNDKFIVRLETFLMDSKKFkrtpi 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 16506820   496 ----------------WTLGYVISLEGAQKLVGANPFGKMlPVDEFL 526
Cdd:pfam01755 155 adygnrafyllksghaGTAGYLITPKAAKKLLKYSKNWPL-PVDDLM 200
COG3306 COG3306
Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope ...
 365-579 1.06e-35

Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442535 [Multi-domain]  Cd Length: 238  Bit Score: 134.36  E-value: 1.06e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820 365 EQEIEVKIVEAVDGKALNTSQLKALNiemlPGYRDPYSSRPLTRGEIGCFLSHYSVWKEVIDRELEKTLVIEDDVRFEHQ 444
Cdd:COG3306  24 RLGLDFEFFDAVDGRDLSEEELARYD----RAKALRRYGRPLTPGEIGCFLSHRKAWQKIVESGLPYALILEDDVILSPD 99

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820 445 FKkklmKLMDNIDQAQLDWELIYIGRKRMQVKEPEKAVPNVAN--LVEADYSYW-TLGYVISLEGAQKLV-GANPFGkmL 520
Cdd:COG3306 100 FA----EVLEALAWLPADWDIVKLETSKRKVFLGRRKIKKLGGyrLVRPYSPPLgTAGYLISRKAAKKLLaLLEPID--R 173

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 16506820 521 PVDEFLpvmynkhpvaeykEYYESRDLKAFSAEPLLIYPThytgqpgylSDTETSTIWD 579
Cdd:COG3306 174 PVDDFL-------------FRFWLHGLRVYQVRPALVIQD---------SGLLGSTIEA 210
Glyco_transf_25 cd06532
Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of ...
 362-526 6.34e-27

Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of Neisseria gonorrhoeae and Lic2A of Haemophilus influenzae. M. catarrhalis Lgt2 catalyzes the addition of galactose (Gal) to the growing chain of LOS on the cell surface. N. gonorrhoeae LgtB and LgtE link Gal-beta(1,4) to GlcNAc (N-acetylglucosamine) and Glc (glucose), respectively. The genes encoding LgtB and LgtE are two genes of a five gene locus involved in the synthesis of gonococcal LOS. LgtE is believed to perform the first step in LOS biosynthesis.


Pssm-ID: 133474  Cd Length: 128  Bit Score: 105.76  E-value: 6.34e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820 362 TLYEQEIEVKIVEAVDGKALNTSQLKAlnieMLPGYRDPYSSRPLTRGEIGCFLSHYSVWKEVIDRELEKTLVIEDDVRF 441
Cdd:cd06532  20 QLAALGLDFEFFDAVDGKDLSEEELAA----LYDALFLPRYGRPLTPGEIGCFLSHYKLWQKIVESNLEYALILEDDAIL 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820 442 EHqfkkklmklmdnidqaqldweliyigrkrmqvkepekavpnvanlveadysYWTLGYVISLEGAQKLVGANPFgKMLP 521
Cdd:cd06532  96 DP---------------------------------------------------DGTAGYLVSRKGAKKLLAALEP-IDLP 123


                ....*
gi 16506820 522 VDEFL 526
Cdd:cd06532 124 VDVFL 128
Glyco_tranf_2_4 pfam13704
Glycosyl transferase family 2; Members of this family of prokaryotic proteins include putative ...
 62-175 5.96e-07

Glycosyl transferase family 2; Members of this family of prokaryotic proteins include putative glucosyltransferases,


Pssm-ID: 433416 [Multi-domain]  Cd Length: 97  Bit Score: 48.01  E-value: 5.96e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820    62 RNAAHTLPHFLGCLERLDYPksrmAIWAATDHNVDNTTEIFREWlKNVQRLYHyvewrpmdepesypdeigPKHWPTSRF 141
Cdd:pfam13704   1 RNEADILPQWLAHHLALGFD----HIYVYDNGSDDGTAEILARL-PDVSILRS------------------DLSYKDARF 57

                          90       100       110
                  ....*....|....*....|....*....|....
gi 16506820   142 AHVMklRQAALRTAreKWSDYILFIDVDNFLTNP 175
Cdd:pfam13704  58 QVDW--RNALLARY--AEADWVLVVDADEFLVYP 87
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 46-183 3.05e-06

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 49.35  E-value: 3.05e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820  46 PESPLQSPTVLVAVLARNAAHTLPHFLGCLERLDYPKSRMAIWAATDHNVDNTTEIFREWLKNVQRLYHYVEwrpmdepe 125
Cdd:COG1215  22 RRAPADLPRVSVIIPAYNEEAVIEETLRSLLAQDYPKEKLEVIVVDDGSTDETAEIARELAAEYPRVRVIER-------- 93

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 16506820 126 syPDEIGPKHwptsrfAhvmklRQAALRTARekwSDYILFIDVDNFLTnPQTLNLLIA 183
Cdd:COG1215  94 --PENGGKAA------A-----LNAGLKAAR---GDIVVFLDADTVLD-PDWLRRLVA 134
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 57-186 8.29e-06

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 46.35  E-value: 8.29e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820  57 VAVLARNAAHTLPHFLGCLERLDYPKSRmaIWAATDHNVDNTTEIFREWLKNVQRLYHYVEWRPMdepesypdeiGPKHW 136
Cdd:cd00761   1 VIIPAYNEEPYLERCLESLLAQTYPNFE--VIVVDDGSTDGTLEILEEYAKKDPRVIRVINEENQ----------GLAAA 68

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
gi 16506820 137 ptsrfahvmklRQAALRTARekwSDYILFIDVDNFLTnPQTLNLLIAENK 186
Cdd:cd00761  69 -----------RNAGLKAAR---GEYILFLDADDLLL-PDWLERLVAELL 103
 
Name Accession Description Interval E-value
Glyco_transf_25 pfam01755
Glycosyltransferase family 25 (LPS biosynthesis protein); Members of this family belong to ...
 341-526 8.77e-43

Glycosyltransferase family 25 (LPS biosynthesis protein); Members of this family belong to Glycosyltransferase family 25 This is a family of glycosyltransferases involved in lipopolysaccharide (LPS) biosynthesis. These enzymes catalyze the transfer of various sugars onto the growing LPS chain during its biosynthesis.


Pssm-ID: 366794  Cd Length: 200  Bit Score: 152.59  E-value: 8.77e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820   341 FDEIFMINLKRRKDRRDRMLRTLYEQEIEVKIVEAVDGKALNTsqlKALNIEMLPGYRDPYSSRPLTRGEIGCFLSHYSV 420
Cdd:pfam01755   1 MIKIYVISLKRATERREHIQKEFGKLNIPFQFFDAIDGKELPN---HLLFKLYNFLLRSKYAGRPLTLGEIGCFLSHYSL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820   421 WKEVIDRELEKTLVIEDDVRFEHQFKKKLMKLMDNIdqaQLDWELIYIGRKRMQVKEPEKAVPNVANLVEADYSY----- 495
Cdd:pfam01755  78 WQKCVELNLEYIIILEDDVILSENFKAILQFLLKEI---NELEFLRLGEWLKTRFDPNDKFIVRLETFLMDSKKFkrtpi 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 16506820   496 ----------------WTLGYVISLEGAQKLVGANPFGKMlPVDEFL 526
Cdd:pfam01755 155 adygnrafyllksghaGTAGYLITPKAAKKLLKYSKNWPL-PVDDLM 200
COG3306 COG3306
Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope ...
 365-579 1.06e-35

Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442535 [Multi-domain]  Cd Length: 238  Bit Score: 134.36  E-value: 1.06e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820 365 EQEIEVKIVEAVDGKALNTSQLKALNiemlPGYRDPYSSRPLTRGEIGCFLSHYSVWKEVIDRELEKTLVIEDDVRFEHQ 444
Cdd:COG3306  24 RLGLDFEFFDAVDGRDLSEEELARYD----RAKALRRYGRPLTPGEIGCFLSHRKAWQKIVESGLPYALILEDDVILSPD 99

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820 445 FKkklmKLMDNIDQAQLDWELIYIGRKRMQVKEPEKAVPNVAN--LVEADYSYW-TLGYVISLEGAQKLV-GANPFGkmL 520
Cdd:COG3306 100 FA----EVLEALAWLPADWDIVKLETSKRKVFLGRRKIKKLGGyrLVRPYSPPLgTAGYLISRKAAKKLLaLLEPID--R 173

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 16506820 521 PVDEFLpvmynkhpvaeykEYYESRDLKAFSAEPLLIYPThytgqpgylSDTETSTIWD 579
Cdd:COG3306 174 PVDDFL-------------FRFWLHGLRVYQVRPALVIQD---------SGLLGSTIEA 210
Glyco_transf_25 cd06532
Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of ...
 362-526 6.34e-27

Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of Neisseria gonorrhoeae and Lic2A of Haemophilus influenzae. M. catarrhalis Lgt2 catalyzes the addition of galactose (Gal) to the growing chain of LOS on the cell surface. N. gonorrhoeae LgtB and LgtE link Gal-beta(1,4) to GlcNAc (N-acetylglucosamine) and Glc (glucose), respectively. The genes encoding LgtB and LgtE are two genes of a five gene locus involved in the synthesis of gonococcal LOS. LgtE is believed to perform the first step in LOS biosynthesis.


Pssm-ID: 133474  Cd Length: 128  Bit Score: 105.76  E-value: 6.34e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820 362 TLYEQEIEVKIVEAVDGKALNTSQLKAlnieMLPGYRDPYSSRPLTRGEIGCFLSHYSVWKEVIDRELEKTLVIEDDVRF 441
Cdd:cd06532  20 QLAALGLDFEFFDAVDGKDLSEEELAA----LYDALFLPRYGRPLTPGEIGCFLSHYKLWQKIVESNLEYALILEDDAIL 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820 442 EHqfkkklmklmdnidqaqldweliyigrkrmqvkepekavpnvanlveadysYWTLGYVISLEGAQKLVGANPFgKMLP 521
Cdd:cd06532  96 DP---------------------------------------------------DGTAGYLVSRKGAKKLLAALEP-IDLP 123


                ....*
gi 16506820 522 VDEFL 526
Cdd:cd06532 124 VDVFL 128
Glyco_tranf_2_4 pfam13704
Glycosyl transferase family 2; Members of this family of prokaryotic proteins include putative ...
 62-175 5.96e-07

Glycosyl transferase family 2; Members of this family of prokaryotic proteins include putative glucosyltransferases,


Pssm-ID: 433416 [Multi-domain]  Cd Length: 97  Bit Score: 48.01  E-value: 5.96e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820    62 RNAAHTLPHFLGCLERLDYPksrmAIWAATDHNVDNTTEIFREWlKNVQRLYHyvewrpmdepesypdeigPKHWPTSRF 141
Cdd:pfam13704   1 RNEADILPQWLAHHLALGFD----HIYVYDNGSDDGTAEILARL-PDVSILRS------------------DLSYKDARF 57

                          90       100       110
                  ....*....|....*....|....*....|....
gi 16506820   142 AHVMklRQAALRTAreKWSDYILFIDVDNFLTNP 175
Cdd:pfam13704  58 QVDW--RNALLARY--AEADWVLVVDADEFLVYP 87
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 46-183 3.05e-06

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 49.35  E-value: 3.05e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820  46 PESPLQSPTVLVAVLARNAAHTLPHFLGCLERLDYPKSRMAIWAATDHNVDNTTEIFREWLKNVQRLYHYVEwrpmdepe 125
Cdd:COG1215  22 RRAPADLPRVSVIIPAYNEEAVIEETLRSLLAQDYPKEKLEVIVVDDGSTDETAEIARELAAEYPRVRVIER-------- 93

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 16506820 126 syPDEIGPKHwptsrfAhvmklRQAALRTARekwSDYILFIDVDNFLTnPQTLNLLIA 183
Cdd:COG1215  94 --PENGGKAA------A-----LNAGLKAAR---GDIVVFLDADTVLD-PDWLRRLVA 134
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 57-186 8.29e-06

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 46.35  E-value: 8.29e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820  57 VAVLARNAAHTLPHFLGCLERLDYPKSRmaIWAATDHNVDNTTEIFREWLKNVQRLYHYVEWRPMdepesypdeiGPKHW 136
Cdd:cd00761   1 VIIPAYNEEPYLERCLESLLAQTYPNFE--VIVVDDGSTDGTLEILEEYAKKDPRVIRVINEENQ----------GLAAA 68

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
gi 16506820 137 ptsrfahvmklRQAALRTARekwSDYILFIDVDNFLTnPQTLNLLIAENK 186
Cdd:cd00761  69 -----------RNAGLKAAR---GEYILFLDADDLLL-PDWLERLVAELL 103
CESA_like_1 cd06439
CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of ...
 41-183 5.23e-05

CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of cellulose synthase (CESA) superfamily. CESA superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members of the superfamily include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins.


Pssm-ID: 133061 [Multi-domain]  Cd Length: 251  Bit Score: 45.27  E-value: 5.23e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16506820  41 EPVVFPESPLQSPTVLVAvlARNAAHTLPHFLGCLERLDYPKSRMAIWAATDHNVDNTTEIFREWLKNVQRLYHYVEWRp 120
Cdd:cd06439  19 PPSLPDPAYLPTVTIIIP--AYNEEAVIEAKLENLLALDYPRDRLEIIVVSDGSTDGTAEIAREYADKGVKLLRFPERR- 95

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16506820 121 mdepesypdeiGpKhwptsrfAHVMKlrqAALRTARekwSDYILFIDVDNFLtNPQTLNLLIA 183
Cdd:cd06439  96 -----------G-K-------AAALN---RALALAT---GEIVVFTDANALL-DPDALRLLVR 132
GT_2_like_e cd04192
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 55-101 3.23e-04

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133035 [Multi-domain]  Cd Length: 229  Bit Score: 42.66  E-value: 3.23e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*..
gi 16506820  55 VLVAvlARNAAHTLPHFLGCLERLDYPKSRMAIWAATDHNVDNTTEI 101
Cdd:cd04192   1 VVIA--ARNEAENLPRLLQSLSALDYPKEKFEVILVDDHSTDGTVQI 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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