NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1822142039|ref|NP_056254|]
View 

coiled-coil domain-containing protein 28A isoform 1 [Homo sapiens]

Protein Classification

CCDC28 family protein( domain architecture ID 10594009)

CCDC28 family protein is a DUF4061 domain-containing protein; similar to homo sapiens coiled-coil domain containing 28A and 28B

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
CCDC28 pfam13270
Coiled-coil domain-containing protein 28; This entry includes CCDC28A and CCDC28B. CCDC28B ...
 83-168 1.04e-30

Coiled-coil domain-containing protein 28; This entry includes CCDC28A and CCDC28B. CCDC28B modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation.


:

Pssm-ID: 463822  Cd Length: 88  Bit Score: 106.98  E-value: 1.04e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822142039  83 SDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPEDKRKTA--SDSNLDRLLSDL 160
Cdd:pfam13270   1 PDVRHMEEGLLQLLEDFHSGKLQAFGKDCSMEQMEEIREQQEKLARLHFELGNEQEEFAEDEEDGLreSDENLTKLVSNL 80


                  ....*...
gi 1822142039 161 EELNSSIQ 168
Cdd:pfam13270  81 EQLSSSIE 88
 
Name Accession Description Interval E-value
CCDC28 pfam13270
Coiled-coil domain-containing protein 28; This entry includes CCDC28A and CCDC28B. CCDC28B ...
 83-168 1.04e-30

Coiled-coil domain-containing protein 28; This entry includes CCDC28A and CCDC28B. CCDC28B modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation.


Pssm-ID: 463822  Cd Length: 88  Bit Score: 106.98  E-value: 1.04e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822142039  83 SDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPEDKRKTA--SDSNLDRLLSDL 160
Cdd:pfam13270   1 PDVRHMEEGLLQLLEDFHSGKLQAFGKDCSMEQMEEIREQQEKLARLHFELGNEQEEFAEDEEDGLreSDENLTKLVSNL 80


                  ....*...
gi 1822142039 161 EELNSSIQ 168
Cdd:pfam13270  81 EQLSSSIE 88
 
Name Accession Description Interval E-value
CCDC28 pfam13270
Coiled-coil domain-containing protein 28; This entry includes CCDC28A and CCDC28B. CCDC28B ...
 83-168 1.04e-30

Coiled-coil domain-containing protein 28; This entry includes CCDC28A and CCDC28B. CCDC28B modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation.


Pssm-ID: 463822  Cd Length: 88  Bit Score: 106.98  E-value: 1.04e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822142039  83 SDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPEDKRKTA--SDSNLDRLLSDL 160
Cdd:pfam13270   1 PDVRHMEEGLLQLLEDFHSGKLQAFGKDCSMEQMEEIREQQEKLARLHFELGNEQEEFAEDEEDGLreSDENLTKLVSNL 80


                  ....*...
gi 1822142039 161 EELNSSIQ 168
Cdd:pfam13270  81 EQLSSSIE 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH