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Conserved domains on  [gi|20149621|ref|NP_056348|]
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triokinase/FMN cyclase isoform b [Homo sapiens]

Protein Classification

dihydroxyacetone kinase family protein( domain architecture ID 11494183)

dihydroxyacetone kinase family protein such as human triokinase/FMN cyclase and Saccharomyces cerevisiae dihydroxyacetone kinases 1 and 2, which catalyze the phosphorylation of both dihydroxyacetone and glyceraldehyde

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
dak_ATP TIGR02361
dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of ...
 4-558 0e+00

dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of dihydroxyacetone kinase (also called glycerone kinase) that uses ATP (2.7.1.29) as the phosphate donor, rather than a phosphoprotein as in E. coli. This form is composed of a single chain with separable domains homologous to the K and L subunits of the E. coli enzyme, and is found in yeasts and other eukaryotes and in some bacteria, including Citrobacter freundii. The member from tomato has been shown to phosphorylate dihydroxyacetone, 3,4-dihydroxy-2-butanone, and some other aldoses and ketoses ().


:

Pssm-ID: 274097 [Multi-domain]  Cd Length: 574  Bit Score: 711.84  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621     4 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 83
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPGLQLLESRKVVYRRDLN--KDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDVFAS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621    84 PAVGSILAAIRAVAQaGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLK--KAGRRGLCGTVLIH 161
Cdd:TIGR02361  79 PSTKQILAAIRAVVG-SEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKggLVGRRGLAGTVLVH 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   162 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGSKPTF-ELSADEVELGLGIHGEAGVRRIKMA-TADEIVK 239
Cdd:TIGR02361 158 KIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEpELKEDEMELGMGIHNEPGAKRISPIpSSDLVVQ 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   240 LMLDHMTNTTNA-SHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARAL-VGTFMSALEMPGISLTLL 317
Cdd:TIGR02361 238 LMLKKLLDETDKrSYVKFNEGDEVVLLVNNLGGVSNLELGIIADEVVEQLALHYNIIPVRIySGTFMTSLNGPGFSITLL 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   318 LVDE---PLLKLIDAETTAAAWPNVAAVSITGRKRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNA 394
Cdd:TIGR02361 318 NATEagkSILDLLDAPTEAPGWPVAAYSSKPWREKREVVSSSAPELIEETAVRSYDPQLVAAILESGCAALLELEPHLTK 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   395 LDRAAGDGDCGTTHSRAARAIQEWLK-EGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSLP---- 469
Cdd:TIGR02361 398 LDTKAGDGDCGSTLARGAEAILELLKsKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASKKeeit 477

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   470 --AWSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPgadllqvLTKAVKSAEAAAEATKNMEAGAGRASYI 547
Cdd:TIGR02361 478 peAWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSN-------LNAAVKAAEAGAEATKKMKAKAGRASYV 550

                         570
                  ....*....|..
gi 20149621   548 SSARLEQ-PDPG 558
Cdd:TIGR02361 551 SSEALEGvPDPG 562
 
Name Accession Description Interval E-value
dak_ATP TIGR02361
dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of ...
 4-558 0e+00

dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of dihydroxyacetone kinase (also called glycerone kinase) that uses ATP (2.7.1.29) as the phosphate donor, rather than a phosphoprotein as in E. coli. This form is composed of a single chain with separable domains homologous to the K and L subunits of the E. coli enzyme, and is found in yeasts and other eukaryotes and in some bacteria, including Citrobacter freundii. The member from tomato has been shown to phosphorylate dihydroxyacetone, 3,4-dihydroxy-2-butanone, and some other aldoses and ketoses ().


Pssm-ID: 274097 [Multi-domain]  Cd Length: 574  Bit Score: 711.84  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621     4 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 83
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPGLQLLESRKVVYRRDLN--KDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDVFAS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621    84 PAVGSILAAIRAVAQaGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLK--KAGRRGLCGTVLIH 161
Cdd:TIGR02361  79 PSTKQILAAIRAVVG-SEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKggLVGRRGLAGTVLVH 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   162 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGSKPTF-ELSADEVELGLGIHGEAGVRRIKMA-TADEIVK 239
Cdd:TIGR02361 158 KIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEpELKEDEMELGMGIHNEPGAKRISPIpSSDLVVQ 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   240 LMLDHMTNTTNA-SHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARAL-VGTFMSALEMPGISLTLL 317
Cdd:TIGR02361 238 LMLKKLLDETDKrSYVKFNEGDEVVLLVNNLGGVSNLELGIIADEVVEQLALHYNIIPVRIySGTFMTSLNGPGFSITLL 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   318 LVDE---PLLKLIDAETTAAAWPNVAAVSITGRKRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNA 394
Cdd:TIGR02361 318 NATEagkSILDLLDAPTEAPGWPVAAYSSKPWREKREVVSSSAPELIEETAVRSYDPQLVAAILESGCAALLELEPHLTK 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   395 LDRAAGDGDCGTTHSRAARAIQEWLK-EGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSLP---- 469
Cdd:TIGR02361 398 LDTKAGDGDCGSTLARGAEAILELLKsKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASKKeeit 477

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   470 --AWSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPgadllqvLTKAVKSAEAAAEATKNMEAGAGRASYI 547
Cdd:TIGR02361 478 peAWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSN-------LNAAVKAAEAGAEATKKMKAKAGRASYV 550

                         570
                  ....*....|..
gi 20149621   548 SSARLEQ-PDPG 558
Cdd:TIGR02361 551 SSEALEGvPDPG 562
PRK14479 PRK14479
dihydroxyacetone kinase; Provisional
 4-558 4.47e-171

dihydroxyacetone kinase; Provisional


Pssm-ID: 237723 [Multi-domain]  Cd Length: 568  Bit Score: 497.03  E-value: 4.47e-171
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621    4 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 83
Cdd:PRK14479   2 KKLINDPSTFVEEMLEGFVAAHPDLVRLVPGGVVRRTPTP--EGKVAVVSGGGSGHEPAFAGYVGPGMLDAAVCGNVFTS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   84 PAVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAF-TVLKKAGRRGLCGTVLIHK 162
Cdd:PRK14479  80 PSADQVYAAIRAADGGA--GVLLIVGNYAGDVMNFGLAAELARAEGIDVRTVVVTDDVASaPSGETAGRRGIAGTVLVFK 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  163 VAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGS-KPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLM 241
Cdd:PRK14479 158 IAGAAAEAGLDLDEVAAIARKANARTRSMGVALDGCTLPGAgEPLFTLPEGEMELGLGIHGEPGIEREALPTADELADRL 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  242 LDHMTNttnasHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVDE 321
Cdd:PRK14479 238 VDRILA-----DLPLGAGERVAVLVNGLGATPYEELFVVYGAVARLLAARGITVVRPEVGEFVTSLDMAGASLTLMKLDD 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  322 PLLKLIDAETTAAAWPNVAAVSITGRkRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNALDRAAGD 401
Cdd:PRK14479 313 ELEELWDAPADTPAFRRGGAVEPVEY-VEAAEEDDAEEPPRASKASRATAANLVAALDAVAEALIDNEDELGELDAVAGD 391

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  402 GDCGTTHSRAARAIQEWLKEGPPP-ASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPL--KAKTSLPAWSAAMDAG 478
Cdd:PRK14479 392 GDHGIGMARGSKAALAAARAAVEAgAGAGSVLAAAGDAWADHAGGTSGPLWGTALRAAGKALgdKDEPTAADFAAAVRAA 471

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  479 LEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATKNMEAGAGRASYISSARLEQPDPG 558
Cdd:PRK14479 472 VDAIQELGGAQVGDKTMVDALVPFADALEAAAAAGADLAEAWAAAAEAAEEGAEATADLVPRMGRARYLGERSLGTPDAG 551
Dak1 pfam02733
Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.
 19-335 1.43e-144

Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.


Pssm-ID: 460667  Cd Length: 312  Bit Score: 419.54  E-value: 1.43e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621    19 AGLVACNPN-LQLLQGHRVALRSDlDSLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTSPAVGSILAAIRAVA 97
Cdd:pfam02733   1 EGLAAAHPDlLRLVPGPRVVVRAD-APPKGKVALISGGGSGHEPAHAGYVGKGMLDAAVPGEVFASPSPDQILAAIKAVD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621    98 QAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAF-TVLKKAGRRGLCGTVLIHKVAGALAEAGVGLEE 176
Cdd:pfam02733  80 GGA--GVLLIVKNYTGDVLNFGMAAELARAEGIKVETVVVGDDVAVgDSGGTVGRRGVAGTVLVHKIAGAAAEAGASLDE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   177 IAKQVNVVAKAMGTLGVSLSSCSVPG-SKPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLMLDHMTNTTnashvP 255
Cdd:pfam02733 158 VARLAEKVNANTRTMGVALSPCTVPGaGKPTFELGEDEMELGMGIHGEPGVKREKLKPADELVEELLDKLLDDD-----P 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   256 VQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVDEPLLKLIDAETTAAA 335
Cdd:pfam02733 233 LLPGDEVAVLVNGLGGTPLLELYIVYRRVLELLEEKGIKVVRSLVGEYMTSLDMAGFSLTLLKLDDELLELLDAPVDTPA 312
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
 378-558 1.60e-25

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 104.13  E-value: 1.60e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621 378 LERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEwlKEGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTA 457
Cdd:COG2376   1 MKAVADVIAENRKFLNDLDAVVGDGDHGINMARGFDAVRA--ALDAAPADPGVVLRAAGMKVASVVGGGSGGLVGTGFLD 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621 458 AAQPLKAKTSLPA--WSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATK 535
Cdd:COG2376  79 AAVALKGETSPTAdqVAAALRAADEGIQGRGVAYTGDKTNFDAAAPAAEAIEEAVAAGTAAAAALDEAAAAAEKGAEATR 158

                       170       180
                ....*....|....*....|...
gi 20149621 536 NMEAGAGRASYISSARLEQPDPG 558
Cdd:COG2376 159 SMGAALGRATYPGERSPGHPDPG 181
 
Name Accession Description Interval E-value
dak_ATP TIGR02361
dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of ...
 4-558 0e+00

dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of dihydroxyacetone kinase (also called glycerone kinase) that uses ATP (2.7.1.29) as the phosphate donor, rather than a phosphoprotein as in E. coli. This form is composed of a single chain with separable domains homologous to the K and L subunits of the E. coli enzyme, and is found in yeasts and other eukaryotes and in some bacteria, including Citrobacter freundii. The member from tomato has been shown to phosphorylate dihydroxyacetone, 3,4-dihydroxy-2-butanone, and some other aldoses and ketoses ().


Pssm-ID: 274097 [Multi-domain]  Cd Length: 574  Bit Score: 711.84  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621     4 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 83
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPGLQLLESRKVVYRRDLN--KDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDVFAS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621    84 PAVGSILAAIRAVAQaGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLK--KAGRRGLCGTVLIH 161
Cdd:TIGR02361  79 PSTKQILAAIRAVVG-SEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKggLVGRRGLAGTVLVH 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   162 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGSKPTF-ELSADEVELGLGIHGEAGVRRIKMA-TADEIVK 239
Cdd:TIGR02361 158 KIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEpELKEDEMELGMGIHNEPGAKRISPIpSSDLVVQ 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   240 LMLDHMTNTTNA-SHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARAL-VGTFMSALEMPGISLTLL 317
Cdd:TIGR02361 238 LMLKKLLDETDKrSYVKFNEGDEVVLLVNNLGGVSNLELGIIADEVVEQLALHYNIIPVRIySGTFMTSLNGPGFSITLL 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   318 LVDE---PLLKLIDAETTAAAWPNVAAVSITGRKRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNA 394
Cdd:TIGR02361 318 NATEagkSILDLLDAPTEAPGWPVAAYSSKPWREKREVVSSSAPELIEETAVRSYDPQLVAAILESGCAALLELEPHLTK 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   395 LDRAAGDGDCGTTHSRAARAIQEWLK-EGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSLP---- 469
Cdd:TIGR02361 398 LDTKAGDGDCGSTLARGAEAILELLKsKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASKKeeit 477

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   470 --AWSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPgadllqvLTKAVKSAEAAAEATKNMEAGAGRASYI 547
Cdd:TIGR02361 478 peAWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSN-------LNAAVKAAEAGAEATKKMKAKAGRASYV 550

                         570
                  ....*....|..
gi 20149621   548 SSARLEQ-PDPG 558
Cdd:TIGR02361 551 SSEALEGvPDPG 562
PRK14479 PRK14479
dihydroxyacetone kinase; Provisional
 4-558 4.47e-171

dihydroxyacetone kinase; Provisional


Pssm-ID: 237723 [Multi-domain]  Cd Length: 568  Bit Score: 497.03  E-value: 4.47e-171
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621    4 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 83
Cdd:PRK14479   2 KKLINDPSTFVEEMLEGFVAAHPDLVRLVPGGVVRRTPTP--EGKVAVVSGGGSGHEPAFAGYVGPGMLDAAVCGNVFTS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   84 PAVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAF-TVLKKAGRRGLCGTVLIHK 162
Cdd:PRK14479  80 PSADQVYAAIRAADGGA--GVLLIVGNYAGDVMNFGLAAELARAEGIDVRTVVVTDDVASaPSGETAGRRGIAGTVLVFK 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  163 VAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGS-KPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLM 241
Cdd:PRK14479 158 IAGAAAEAGLDLDEVAAIARKANARTRSMGVALDGCTLPGAgEPLFTLPEGEMELGLGIHGEPGIEREALPTADELADRL 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  242 LDHMTNttnasHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVDE 321
Cdd:PRK14479 238 VDRILA-----DLPLGAGERVAVLVNGLGATPYEELFVVYGAVARLLAARGITVVRPEVGEFVTSLDMAGASLTLMKLDD 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  322 PLLKLIDAETTAAAWPNVAAVSITGRkRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNALDRAAGD 401
Cdd:PRK14479 313 ELEELWDAPADTPAFRRGGAVEPVEY-VEAAEEDDAEEPPRASKASRATAANLVAALDAVAEALIDNEDELGELDAVAGD 391

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  402 GDCGTTHSRAARAIQEWLKEGPPP-ASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPL--KAKTSLPAWSAAMDAG 478
Cdd:PRK14479 392 GDHGIGMARGSKAALAAARAAVEAgAGAGSVLAAAGDAWADHAGGTSGPLWGTALRAAGKALgdKDEPTAADFAAAVRAA 471

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  479 LEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATKNMEAGAGRASYISSARLEQPDPG 558
Cdd:PRK14479 472 VDAIQELGGAQVGDKTMVDALVPFADALEAAAAAGADLAEAWAAAAEAAEEGAEATADLVPRMGRARYLGERSLGTPDAG 551
PTZ00375 PTZ00375
dihydroxyacetone kinase-like protein; Provisional
 1-558 1.01e-151

dihydroxyacetone kinase-like protein; Provisional


Pssm-ID: 185583 [Multi-domain]  Cd Length: 584  Bit Score: 448.11  E-value: 1.01e-151
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621    1 MTSKKLVNSVAGCADDALAGLVACNPN-LQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGA 79
Cdd:PTZ00375   1 MVSKKFINSPEKVVSEAVDGLCMTNNDsLKRIENTNVVVRSDID--KTKVLLISGGGSGHEPAHAGFVGKGWLTAAVCGS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   80 VFTSPAVGSILAAIRAVAqaGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLKKAGRRGLCGTVL 159
Cdd:PTZ00375  79 VFASPSTKHVLAAIEYVP--NGPGCLLIVKNYTGDILNFELAVEQARARGIQVETVLVADDAAFGTKDIANRRGIAGTVL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  160 IHKVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGSKPTFELSADEVELGLGIHGEAGVRRIKMATADEIVK 239
Cdd:PTZ00375 157 LYKILGAAAEKGASLTQLKKLADRISSNMRSIGVSLSSCSLPGNDPSSTVPPGTMEVGLGIHGEKGLARIPFQGAKDLVK 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  240 LMLDHMTNTTNA----SHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLT 315
Cdd:PTZ00375 237 FLIGILLGKGKKrgggKTTAIREGAKVALLVNNLGSTTDLEMSILAHHALRQLAQAGLTVVGVHSGRLMTSLEMHGFSLT 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  316 LLLV-DEPLLKLIDAETTAAAWPNVAAVSITGRKRSRVA--PAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHL 392
Cdd:PTZ00375 317 LLPIeDEDDLQLLDTNQKPLLNFHTPQSSWATAKGPLSAlqLAKPEAEAASRKAATPTNSLLRSVLERVFETLIESENYL 396

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  393 NALDRAAGDGDCGTTHSRAARAIQEWLKEGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLT----AAAQPLKAKTSL 468
Cdd:PTZ00375 397 NELDAEVGDGDLGSGLERSSKAVLESLPYLPLEANVRKTLTLISKAVADAFGGSSGPLYGAFLLgganALAEALNGGNAV 476

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  469 PAWSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKS--PGADLLQVLTKAVKSAEAAAEATKNMEAGAGRASY 546
Cdd:PTZ00375 477 DAVRAALAAGSHSIQELGGARVGDRTMVDVLIPFAEALNSCPSvnEAASSPELLKACSEEAREAAEATALLPAKHGRSRY 556

                        570
                 ....*....|..
gi 20149621  547 ISSARLEQPDPG 558
Cdd:PTZ00375 557 LEGKELGKKDPG 568
Dak1 pfam02733
Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.
 19-335 1.43e-144

Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.


Pssm-ID: 460667  Cd Length: 312  Bit Score: 419.54  E-value: 1.43e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621    19 AGLVACNPN-LQLLQGHRVALRSDlDSLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTSPAVGSILAAIRAVA 97
Cdd:pfam02733   1 EGLAAAHPDlLRLVPGPRVVVRAD-APPKGKVALISGGGSGHEPAHAGYVGKGMLDAAVPGEVFASPSPDQILAAIKAVD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621    98 QAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAF-TVLKKAGRRGLCGTVLIHKVAGALAEAGVGLEE 176
Cdd:pfam02733  80 GGA--GVLLIVKNYTGDVLNFGMAAELARAEGIKVETVVVGDDVAVgDSGGTVGRRGVAGTVLVHKIAGAAAEAGASLDE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   177 IAKQVNVVAKAMGTLGVSLSSCSVPG-SKPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLMLDHMTNTTnashvP 255
Cdd:pfam02733 158 VARLAEKVNANTRTMGVALSPCTVPGaGKPTFELGEDEMELGMGIHGEPGVKREKLKPADELVEELLDKLLDDD-----P 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   256 VQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVDEPLLKLIDAETTAAA 335
Cdd:pfam02733 233 LLPGDEVAVLVNGLGGTPLLELYIVYRRVLELLEEKGIKVVRSLVGEYMTSLDMAGFSLTLLKLDDELLELLDAPVDTPA 312
PRK14481 PRK14481
dihydroxyacetone kinase subunit DhaK; Provisional
 4-336 9.12e-121

dihydroxyacetone kinase subunit DhaK; Provisional


Pssm-ID: 237724  Cd Length: 331  Bit Score: 359.51  E-value: 9.12e-121
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621    4 KKLVNSVAGCADDALAGLVACNPNL-QLLQGHRVALRSDLDSlkGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFT 82
Cdd:PRK14481   2 KKLINDPETVVDEMLEGLVAAHPDLvTRIDDTDVIVRKDKPP--GKVALVSGGGSGHEPAHAGFVGEGMLDAAVCGAVFT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   83 SPAVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFT-VLKKAGRRGLCGTVLIH 161
Cdd:PRK14481  80 SPTPDQILEAIKAVDTGA--GVLLIVKNYSGDVMNFEMAAELAEMEGIEVASVVVDDDVAVEdSLYTQGRRGVAGTVFVH 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  162 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGS-KPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKL 240
Cdd:PRK14481 158 KIAGAAAEAGASLDEVKALAEKVNPNIRSMGVALSPCTVPAVgKPGFDLGDDEIEIGIGIHGEPGRRREKLKPADEIAEE 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  241 MLDHMTNTtnashVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVD 320
Cdd:PRK14481 238 LLEKILED-----LKLVAGDEVLVLVNGMGATPLMELYIVYNDVAELLEERGVTVARSLVGNYMTSLDMAGFSITLLKLD 312

                        330
                 ....*....|....*.
gi 20149621  321 EPLLKLIDAETTAAAW 336
Cdd:PRK14481 313 DELLELLDAPVDTPAL 328
dhaK1 TIGR02363
dihydroxyacetone kinase, DhaK subunit; Two types of dihydroxyacetone kinase (glycerone kinase) ...
 4-336 6.80e-115

dihydroxyacetone kinase, DhaK subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the DhaK subunit of the latter type of dihydroxyacetone kinase, but it specifically excludes the DhaK paralog DhaK2 (TIGR02362) found in the same operon as DhaK and DhaK in the Firmicutes.


Pssm-ID: 274098  Cd Length: 329  Bit Score: 344.73  E-value: 6.80e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621     4 KKLVNSVAGCADDALAGLVACNPNL-QLLQGHRVALRSDLDSlKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFT 82
Cdd:TIGR02363   2 KKLINDPEDVVAEMLDGLVKAHPELvTLVADTRVIVRKDKKV-NGKVALVSGGGSGHEPAHAGFVGYGMLDAAVPGEVFT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621    83 SPAVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFT-VLKKAGRRGLCGTVLIH 161
Cdd:TIGR02363  81 SPTPDQILEAIKAVDQGA--GVLLIVKNYTGDVMNFEMAAELAEDEGIKVATVVVDDDIAVEdSLYTAGRRGVAGTVFVH 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   162 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGS-KPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKL 240
Cdd:TIGR02363 159 KIAGAAAEKGASLDELKSLGEKVNPNTKSIGVALTACTVPAVgKPGFDLADDEMEIGVGIHGEPGIRREKMKSSDEIADE 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   241 MLDHMtnttnASHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVD 320
Cdd:TIGR02363 239 LLDKL-----LDDLGLQSGDRVIVLVNGMGATPLMELYIFYNDVQRLLEQRGVNVARTLVGNYMTSLDMAGFSLTLLKLD 313

                         330
                  ....*....|....*.
gi 20149621   321 EPLLKLIDAETTAAAW 336
Cdd:TIGR02363 314 DELLELWDAPVTTIAL 329
PRK11468 PRK11468
dihydroxyacetone kinase subunit DhaK; Provisional
 4-336 9.28e-96

dihydroxyacetone kinase subunit DhaK; Provisional


Pssm-ID: 183150  Cd Length: 356  Bit Score: 296.54  E-value: 9.28e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621    4 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDsLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 83
Cdd:PRK11468   2 KKLINDVEDVLDEQLAGLAKAHPELTLHQDPVYVTRADAP-VAGKVALLSGGGSGHEPMHCGFVGQGMLDGACPGEIFTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   84 PAVGSILAAIRAVaqAGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFT-VLKKAGRRGLCGTVLIHK 162
Cdd:PRK11468  81 PTPDQMFECAMQV--DGGEGVLLIIKNYTGDVLNFETATELLHDSGVKVTTVLIDDDVAVKdSLYTAGRRGVANTVLIEK 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  163 VAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGS-KPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLM 241
Cdd:PRK11468 159 LVGAAAERGYSLDQCAELGRKLNNQGHSIGIALGACTVPAAgKPSFTLADNEMEFGVGIHGEPGIDRRPFSSLDQTVDEM 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  242 LDHMTNTTNASHV-------------------PVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGT 302
Cdd:PRK11468 239 FDTLLENGSYHRTlrfwdrqqgswqeeeqtkqPLQSGDRVIALVNNLGATPLSELYGVYNRLATRCEQAGLTIERNLIGA 318

                        330       340       350
                 ....*....|....*....|....*....|....
gi 20149621  303 FMSALEMPGISLTLLLVDEPLLKLIDAETTAAAW 336
Cdd:PRK11468 319 YCTSLDMQGFSITLLKVDDETLALWDAPVHTPAL 352
PRK14483 PRK14483
DhaKLM operon coactivator DhaQ; Provisional
 4-336 2.32e-79

DhaKLM operon coactivator DhaQ; Provisional


Pssm-ID: 172956  Cd Length: 329  Bit Score: 253.05  E-value: 2.32e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621    4 KKLVNSVAGCADDALAGLVACNPNLQllQGHRVALRSDLDSLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 83
Cdd:PRK14483   2 KKIMNDVQNIVQDMLHGFYFAHPNLD--ETNNIPYVYDIEKDDQLVPIISGGGSGHEPAHIGYVGKGMLTAAVNGSIFTP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   84 PAVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLK--KAGRRGLCGTVLIH 161
Cdd:PRK14483  80 PTAEQILAATRLVPKGK--GVFFIIKNFEADVAEFSAAIQIARQEGRQIKYIIVHDDISVEDDAsfNKRRRGVAGTVLLH 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  162 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPG-SKPTFELSADEVELGLGIHGEAGVRRIKMAT----ADE 236
Cdd:PRK14483 158 KILGAAALEGASLDELEQLGLSLTENIATLGVALSPANLPVaGLPSFDLNEDEISYGIGIHGEPGYRKEPFSSseilAIE 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  237 IV-KLmldhmtnttnASHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLT 315
Cdd:PRK14483 238 LVnKL----------KSKYRWQKGDNFILLINGLGATTLMEQYIFANDIRRLLELEGLQITFVKVGTLLTSLDMKGISLT 307

                        330       340
                 ....*....|....*....|..
gi 20149621  316 LLLV-DEPLLKLIDAETTAAAW 336
Cdd:PRK14483 308 LLKVkDPDWLDWLKAPTRAAAW 329
dhaK1b TIGR02362
probable dihydroxyacetone kinase DhaK1b subunit; Two types of dihydroxyacetone kinase ...
 5-336 3.55e-68

probable dihydroxyacetone kinase DhaK1b subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form with a phosphoprotein donor related to PTS transport proteins. This family represents a protein, unique to the Firmicutes (low GC Gram-positives), that appears to be a divergent second copy of the K subunit of that complex; its gene is always found in operons with the other three proteins of the complex.


Pssm-ID: 213706  Cd Length: 326  Bit Score: 223.52  E-value: 3.55e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621     5 KLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTSP 84
Cdd:TIGR02362   1 KIINEPQNAVSQAIQGIQWAYPNLVQVPDLPGIYDSNFD--DQQIPIISGGGSGHEPAHWGYVGEGMLSAAIMGDVFVPP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621    85 AVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDD-SAFTVLKKAGRRGLCGTVLIHKV 163
Cdd:TIGR02362  79 TAQDILEAIRQVDRGK--GVFVIIKNFEADLSEFSQAIQQARQEGRQIKYIIVHDDiSVEHESFKQRRRGVAGTILVHKI 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   164 AGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPG-SKPTFELSADEVELGLGIHGEAGVRRIKMAT----ADEIV 238
Cdd:TIGR02362 157 LGAAAAEGASLDELEHIAAALVTNIATIGVAAKSARIPGqSTPSFDLEEGEIYYGIGIHGEPGYRTEPFVSsehlAVELV 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   239 -KLMLDHMTnttnashvpvQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLL 317
Cdd:TIGR02362 237 nKLKLKFRW----------QADDHYAVLVNNLGGTTPMEQMVFNNDVHELLALEALHLPFIKVGTFLTSLDMHGLSLTLL 306

                         330       340
                  ....*....|....*....|
gi 20149621   318 -LVDEPLLKLIDAETTAAAW 336
Cdd:TIGR02362 307 rLKDPQWLDYLNAPVDAAAW 326
Dak2 pfam02734
DAK2 domain; This domain is the predicted phosphatase domain of the dihydroxyacetone kinase ...
 398-558 1.03e-43

DAK2 domain; This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family.


Pssm-ID: 460668 [Multi-domain]  Cd Length: 175  Bit Score: 153.49  E-value: 1.03e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   398 AAGDGDCGTTHSRAARAIQEWLKEGPPpASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSL--PAWSAAM 475
Cdd:pfam02734   1 PVGDGDHGTNMARGFEAALKALEDLEP-ASLAEVLKALAMALLSGAGGNSGPLYGQFFRGAAKALKGKEELdaEDLAAAL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   476 DAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATKNMEAGAGRASYISSARLEQP 555
Cdd:pfam02734  80 EAALEAIQARGKARPGDKTMLDVLRPAAEALEAAAEAGEDLAEALEAAVKAAEEGAEATKELLAKLGRASYLGERSIGVV 159


                  ...
gi 20149621   556 DPG 558
Cdd:pfam02734 160 DPG 162
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
 378-558 1.60e-25

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 104.13  E-value: 1.60e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621 378 LERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEwlKEGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTA 457
Cdd:COG2376   1 MKAVADVIAENRKFLNDLDAVVGDGDHGINMARGFDAVRA--ALDAAPADPGVVLRAAGMKVASVVGGGSGGLVGTGFLD 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621 458 AAQPLKAKTSLPA--WSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATK 535
Cdd:COG2376  79 AAVALKGETSPTAdqVAAALRAADEGIQGRGVAYTGDKTNFDAAAPAAEAIEEAVAAGTAAAAALDEAAAAAEKGAEATR 158

                       170       180
                ....*....|....*....|...
gi 20149621 536 NMEAGAGRASYISSARLEQPDPG 558
Cdd:COG2376 159 SMGAALGRATYPGERSPGHPDPG 181
dha_L_ycgS TIGR02365
dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Two types of dihydroxyacetone ...
 378-558 2.07e-25

dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the subunit homologous to the E. coli YcgS subunit.


Pssm-ID: 274099 [Multi-domain]  Cd Length: 194  Bit Score: 103.58  E-value: 2.07e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   378 LERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEWLKEgPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTA 457
Cdd:TIGR02365   5 LKNCGDLIIENKEYLTELDRAIGDGDHGINMARGFSEVKEKLDA-FKDKTIGEILKNTGMTLISKVGGASGPLYGTAFLK 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   458 AAQPLKAKTSLPAWSAA--MDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAwkspGADLLQVLTKAVKSAEAAAEATK 535
Cdd:TIGR02365  84 ASKALKDDEILDAEDLAeiLQAGLEGIQSRGKATPGEKTMVDVWAPVVEALRK----AADEPDALAAAREAAEQGAEATK 159

                         170       180
                  ....*....|....*....|...
gi 20149621   536 NMEAGAGRASYISSARLEQPDPG 558
Cdd:TIGR02365 160 DMQATKGRASYLGERSIGHIDPG 182
PRK10005 PRK10005
dihydroxyacetone kinase ADP-binding subunit DhaL;
378-558 5.02e-21

dihydroxyacetone kinase ADP-binding subunit DhaL;


Pssm-ID: 182192 [Multi-domain]  Cd Length: 210  Bit Score: 91.72  E-value: 5.02e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  378 LERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEWLkegPPPASP--AQLLSKLSVLLLEKMGGSSGALYGLFL 455
Cdd:PRK10005  12 LTRCGDIFTEESDYLTGLDREIGDADHGLNMNRGFSKVVEKL---PAIADKdiGFILKNTGMTLLSSVGGASGPLYGTFF 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  456 TAAAQPLKAKTSLPA--WSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEA 533
Cdd:PRK10005  89 IRAAQATQARQSLTLeeLYQMFRDGADGVISRGKAEPGDKTMCDVWVPVVESLRQSSEQNLSVPAALNAAVSIAESAAQS 168

                        170       180
                 ....*....|....*....|....*
gi 20149621  534 TKNMEAGAGRASYISSARLEQPDPG 558
Cdd:PRK10005 169 TITMQARKGRASYLGERSIGHQDPG 193
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
 4-202 1.97e-12

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 66.38  E-value: 1.97e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621   4 KKLVNSVAGCADDALAGLVACNPN---LQLLQGHRVALRSDLDSLKGRVALLSGGGSGhepahaGFIGKGMLTGVIAGAV 80
Cdd:COG2376  12 RKFLNDLDAVVGDGDHGINMARGFdavRAALDAAPADPGVVLRAAGMKVASVVGGGSG------GLVGTGFLDAAVALKG 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149621  81 FTSPAVGSILAAIRAVAQA-GTVGtllivKNYTGDRLNFGLAREQARAegipvemvvigddsaftvLKKAGRRGLcgtvl 159
Cdd:COG2376  86 ETSPTADQVAAALRAADEGiQGRG-----VAYTGDKTNFDAAAPAAEA------------------IEEAVAAGT----- 137

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 20149621 160 ihkvagALAEAgvgLEEIAKQVNVVAKAMGTLGVSLSSCSVPG 202
Cdd:COG2376 138 ------AAAAA---LDEAAAAAEKGAEATRSMGAALGRATYPG 171
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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