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Conserved domains on  [gi|7657104|ref|NP_056529|]
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G0/G1 switch protein 2 [Homo sapiens]

Protein Classification

G0-G1_switch_2 domain-containing protein( domain architecture ID 10633434)

G0-G1_switch_2 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
G0-G1_switch_2 pfam15103
G0/G1 switch protein 2; This family of proteins regulate apoptosis by binding to Bcl-2 and ...
 1-103 1.14e-55

G0/G1 switch protein 2; This family of proteins regulate apoptosis by binding to Bcl-2 and preventing the formation of the anti-apoptotic BAX-BCL2 heterodimers.


:

Pssm-ID: 464504  Cd Length: 105  Bit Score: 167.57  E-value: 1.14e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657104      1 METVQELIPLAKEMMAQKRKGKMVKLYVLGSVLALFGVVLGLMETVCSPFTAARRLRDQEAAVAELQAALERQALQKQA- 79
Cdd:pfam15103   1 METVQELIPFAKEMLSQKPSRKMVKLYVLGSVLAFFGVVIGLVETVCSPFTAASRLREEEAAVAELRAARERQAPQKQEm 80

                          90       100
                  ....*....|....*....|....*
gi 7657104     80 -LQEKGKQQDTVLGGRALSNRQHAS 103
Cdd:pfam15103  81 lVLEKGKQQEAPLCQRALSNRQHAS 105
 
Name Accession Description Interval E-value
G0-G1_switch_2 pfam15103
G0/G1 switch protein 2; This family of proteins regulate apoptosis by binding to Bcl-2 and ...
 1-103 1.14e-55

G0/G1 switch protein 2; This family of proteins regulate apoptosis by binding to Bcl-2 and preventing the formation of the anti-apoptotic BAX-BCL2 heterodimers.


Pssm-ID: 464504  Cd Length: 105  Bit Score: 167.57  E-value: 1.14e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657104      1 METVQELIPLAKEMMAQKRKGKMVKLYVLGSVLALFGVVLGLMETVCSPFTAARRLRDQEAAVAELQAALERQALQKQA- 79
Cdd:pfam15103   1 METVQELIPFAKEMLSQKPSRKMVKLYVLGSVLAFFGVVIGLVETVCSPFTAASRLREEEAAVAELRAARERQAPQKQEm 80

                          90       100
                  ....*....|....*....|....*
gi 7657104     80 -LQEKGKQQDTVLGGRALSNRQHAS 103
Cdd:pfam15103  81 lVLEKGKQQEAPLCQRALSNRQHAS 105
 
Name Accession Description Interval E-value
G0-G1_switch_2 pfam15103
G0/G1 switch protein 2; This family of proteins regulate apoptosis by binding to Bcl-2 and ...
 1-103 1.14e-55

G0/G1 switch protein 2; This family of proteins regulate apoptosis by binding to Bcl-2 and preventing the formation of the anti-apoptotic BAX-BCL2 heterodimers.


Pssm-ID: 464504  Cd Length: 105  Bit Score: 167.57  E-value: 1.14e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7657104      1 METVQELIPLAKEMMAQKRKGKMVKLYVLGSVLALFGVVLGLMETVCSPFTAARRLRDQEAAVAELQAALERQALQKQA- 79
Cdd:pfam15103   1 METVQELIPFAKEMLSQKPSRKMVKLYVLGSVLAFFGVVIGLVETVCSPFTAASRLREEEAAVAELRAARERQAPQKQEm 80

                          90       100
                  ....*....|....*....|....*
gi 7657104     80 -LQEKGKQQDTVLGGRALSNRQHAS 103
Cdd:pfam15103  81 lVLEKGKQQEAPLCQRALSNRQHAS 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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