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Conserved domains on  [gi|49619239|ref|NP_057462|]
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variable charge X-linked protein 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
VCX_VCY super family cl27453
Variable charge X/Y family; The variable charge X/Y (VCX/VCY) family of proteins has members ...
 1-125 1.58e-28

Variable charge X/Y family; The variable charge X/Y (VCX/VCY) family of proteins has members on the Human X and Y chromosomes, is expressed in male germ calls and may play a role in spermatogenesis or in sex ratio distortion.


The actual alignment was detected with superfamily member pfam15231:

Pssm-ID: 434553 [Multi-domain]  Cd Length: 130  Bit Score: 101.42  E-value: 1.58e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 49619239     1 MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPGPSDQP 80
Cdd:pfam15231   1 MAPKPRASGPPAKAKEAGKRKSISLLSFQDPKKKEGKRAKAGKAGRGGKRGKKAAAKKMAAVGAPEAESGPAAPGPSDQP 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 49619239    81 SQELPQHELPPEE-PVSEGTQHDPLSQESEVEEPLSQESEVEEPLT 125
Cdd:pfam15231  81 SQELPPCELPPEEePVSEGTQHDPLSQESELEDPLNQESEPEEALN 126
 
Name Accession Description Interval E-value
VCX_VCY pfam15231
Variable charge X/Y family; The variable charge X/Y (VCX/VCY) family of proteins has members ...
 1-125 1.58e-28

Variable charge X/Y family; The variable charge X/Y (VCX/VCY) family of proteins has members on the Human X and Y chromosomes, is expressed in male germ calls and may play a role in spermatogenesis or in sex ratio distortion.


Pssm-ID: 434553 [Multi-domain]  Cd Length: 130  Bit Score: 101.42  E-value: 1.58e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 49619239     1 MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPGPSDQP 80
Cdd:pfam15231   1 MAPKPRASGPPAKAKEAGKRKSISLLSFQDPKKKEGKRAKAGKAGRGGKRGKKAAAKKMAAVGAPEAESGPAAPGPSDQP 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 49619239    81 SQELPQHELPPEE-PVSEGTQHDPLSQESEVEEPLSQESEVEEPLT 125
Cdd:pfam15231  81 SQELPPCELPPEEePVSEGTQHDPLSQESELEDPLNQESEPEEALN 126
 
Name Accession Description Interval E-value
VCX_VCY pfam15231
Variable charge X/Y family; The variable charge X/Y (VCX/VCY) family of proteins has members ...
 1-125 1.58e-28

Variable charge X/Y family; The variable charge X/Y (VCX/VCY) family of proteins has members on the Human X and Y chromosomes, is expressed in male germ calls and may play a role in spermatogenesis or in sex ratio distortion.


Pssm-ID: 434553 [Multi-domain]  Cd Length: 130  Bit Score: 101.42  E-value: 1.58e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 49619239     1 MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPGPSDQP 80
Cdd:pfam15231   1 MAPKPRASGPPAKAKEAGKRKSISLLSFQDPKKKEGKRAKAGKAGRGGKRGKKAAAKKMAAVGAPEAESGPAAPGPSDQP 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 49619239    81 SQELPQHELPPEE-PVSEGTQHDPLSQESEVEEPLSQESEVEEPLT 125
Cdd:pfam15231  81 SQELPPCELPPEEePVSEGTQHDPLSQESELEDPLNQESEPEEALN 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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