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Conserved domains on  [gi|7705997|ref|NP_057538|]
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ER membrane protein complex subunit 4 isoform a [Homo sapiens]

Protein Classification

ER membrane protein complex subunit 4( domain architecture ID 10533988)

ER membrane protein complex subunit 4 (EMC4) is a component of the ER membrane protein complex (EMC) required for efficient folding of proteins in the endoplasmic reticulum (ER)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF1077 pfam06417
Protein of unknown function (DUF1077); This family consists of several hypothetical eukaryotic ...
 56-170 1.99e-62

Protein of unknown function (DUF1077); This family consists of several hypothetical eukaryotic proteins of unknown function.


:

Pssm-ID: 461902  Cd Length: 118  Bit Score: 188.55  E-value: 1.99e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7705997     56 SVQETDRILVEKRCWDIALGPLKQIPMNLFIMYMAGNTISIFPTMMVCMMAWRPIQALMAISATFKMLESS---SQKFLQ 132
Cdd:pfam06417   1 SSKEELEALKVKKAWEIALAPAKSLPMNLFMMYMSGNSLQIFSIMMVGMLLWNPIKAIFSINKAFKPFEGNkniSQLLLQ 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 7705997    133 GLVYLIGNLMGLALAVYKCQSMGLLPTHASDWLAFIEP 170
Cdd:pfam06417  81 KLVYVLCQLLLLALGLYKLNSMGLLPTTSSDWLAFEPP 118
 
Name Accession Description Interval E-value
DUF1077 pfam06417
Protein of unknown function (DUF1077); This family consists of several hypothetical eukaryotic ...
 56-170 1.99e-62

Protein of unknown function (DUF1077); This family consists of several hypothetical eukaryotic proteins of unknown function.


Pssm-ID: 461902  Cd Length: 118  Bit Score: 188.55  E-value: 1.99e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7705997     56 SVQETDRILVEKRCWDIALGPLKQIPMNLFIMYMAGNTISIFPTMMVCMMAWRPIQALMAISATFKMLESS---SQKFLQ 132
Cdd:pfam06417   1 SSKEELEALKVKKAWEIALAPAKSLPMNLFMMYMSGNSLQIFSIMMVGMLLWNPIKAIFSINKAFKPFEGNkniSQLLLQ 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 7705997    133 GLVYLIGNLMGLALAVYKCQSMGLLPTHASDWLAFIEP 170
Cdd:pfam06417  81 KLVYVLCQLLLLALGLYKLNSMGLLPTTSSDWLAFEPP 118
 
Name Accession Description Interval E-value
DUF1077 pfam06417
Protein of unknown function (DUF1077); This family consists of several hypothetical eukaryotic ...
 56-170 1.99e-62

Protein of unknown function (DUF1077); This family consists of several hypothetical eukaryotic proteins of unknown function.


Pssm-ID: 461902  Cd Length: 118  Bit Score: 188.55  E-value: 1.99e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7705997     56 SVQETDRILVEKRCWDIALGPLKQIPMNLFIMYMAGNTISIFPTMMVCMMAWRPIQALMAISATFKMLESS---SQKFLQ 132
Cdd:pfam06417   1 SSKEELEALKVKKAWEIALAPAKSLPMNLFMMYMSGNSLQIFSIMMVGMLLWNPIKAIFSINKAFKPFEGNkniSQLLLQ 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 7705997    133 GLVYLIGNLMGLALAVYKCQSMGLLPTHASDWLAFIEP 170
Cdd:pfam06417  81 KLVYVLCQLLLLALGLYKLNSMGLLPTTSSDWLAFEPP 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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