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vacuolar protein sorting-associated protein VTA1 homolog isoform a [Homo sapiens]
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
Vta1 | pfam04652 | Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ... |
22-152 | 3.37e-65 | |||
Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region. : Pssm-ID: 461380 Cd Length: 133 Bit Score: 200.87 E-value: 3.37e-65
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Vta1_C | pfam18097 | Vta1 C-terminal domain; This is the C-terminal domain of Vta1 proteins pfam04652. Structural ... |
266-303 | 4.40e-16 | |||
Vta1 C-terminal domain; This is the C-terminal domain of Vta1 proteins pfam04652. Structural and functional analysis indicate that this C-terminal domain promotes the ATP-dependent double ring assembly of Vps4. Furthermore, it has been shown that it is necessary and sufficient for protein dimerization. Mutations in Lys-299 and Lys-302 completely abolished the ability of Vta1 to stimulate the ATPase activity of Vps4 while mutation in Lys-322 had no effect. : Pssm-ID: 465647 Cd Length: 38 Bit Score: 70.77 E-value: 4.40e-16
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Name | Accession | Description | Interval | E-value | |||
Vta1 | pfam04652 | Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ... |
22-152 | 3.37e-65 | |||
Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region. Pssm-ID: 461380 Cd Length: 133 Bit Score: 200.87 E-value: 3.37e-65
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Vta1_C | pfam18097 | Vta1 C-terminal domain; This is the C-terminal domain of Vta1 proteins pfam04652. Structural ... |
266-303 | 4.40e-16 | |||
Vta1 C-terminal domain; This is the C-terminal domain of Vta1 proteins pfam04652. Structural and functional analysis indicate that this C-terminal domain promotes the ATP-dependent double ring assembly of Vps4. Furthermore, it has been shown that it is necessary and sufficient for protein dimerization. Mutations in Lys-299 and Lys-302 completely abolished the ability of Vta1 to stimulate the ATPase activity of Vps4 while mutation in Lys-322 had no effect. Pssm-ID: 465647 Cd Length: 38 Bit Score: 70.77 E-value: 4.40e-16
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Name | Accession | Description | Interval | E-value | |||
Vta1 | pfam04652 | Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ... |
22-152 | 3.37e-65 | |||
Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region. Pssm-ID: 461380 Cd Length: 133 Bit Score: 200.87 E-value: 3.37e-65
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Vta1_C | pfam18097 | Vta1 C-terminal domain; This is the C-terminal domain of Vta1 proteins pfam04652. Structural ... |
266-303 | 4.40e-16 | |||
Vta1 C-terminal domain; This is the C-terminal domain of Vta1 proteins pfam04652. Structural and functional analysis indicate that this C-terminal domain promotes the ATP-dependent double ring assembly of Vps4. Furthermore, it has been shown that it is necessary and sufficient for protein dimerization. Mutations in Lys-299 and Lys-302 completely abolished the ability of Vta1 to stimulate the ATPase activity of Vps4 while mutation in Lys-322 had no effect. Pssm-ID: 465647 Cd Length: 38 Bit Score: 70.77 E-value: 4.40e-16
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Blast search parameters | ||||
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