|
Name |
Accession |
Description |
Interval |
E-value |
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
521-1070 |
5.06e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 76.90 E-value: 5.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 521 LKKLKAKLQSLKTECEEARHSKEMALKGKAAAEAVLEAFRAHASQRISQLEQGLTSMQEFRGLLQEAQTQLIGLHTEQKE 600
Cdd:COG1196 234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 601 LAQQTVSLSSALQQdwtsvqlnygiWAALLSWSRELTKKLTAKSRQALQERDAAIEEKKQVVKEVEQVSAHLEDCKGQIE 680
Cdd:COG1196 314 LEERLEELEEELAE-----------LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 681 QLKLENSRLTADLSAQLQILTSTESQLKEVRSQHSRCVQDLAVKDELLcqltQSNKEQATQWQKEEMELKHIQAELLQQQ 760
Cdd:COG1196 383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEAL----AELEEEEEEEEEALEEAAEEEAELEEEE 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 761 AVLAKEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELAStEAKHEKQALEKTHQ 840
Cdd:COG1196 459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA-GAVAVLIGVEAAYE 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 841 HSQELRLLAEQLQSLT------LFLQAKLKENKAESEIILPSTGSAPAQEHPLSNDSSISEQTP-TAAVDEVPEPAPVPL 913
Cdd:COG1196 538 AALEAALAAALQNIVVeddevaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVdLVASDLREADARYYV 617
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 914 LGS---VKSAFTRVASMASFQPTETPDLEKSLAEMSTVLQELKSLCSLLQESKEEATGVLQREICELHSRLQAQEEEHQE 990
Cdd:COG1196 618 LGDtllGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE 697
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 991 ALKAKEADMEKLNQALCLLRKNEKELLEVIQKQNEKILgqidksgQLINLREEVTQLTQSLRRAETETKVLQEALEGQLD 1070
Cdd:COG1196 698 ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE-------ELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
634-889 |
6.18e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.47 E-value: 6.18e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 634 RELTKKLTAKS-RQALQERDAAIEEKKQVVKEVEQVSAHLEDCKGQIEQLKLENSRL-------TADLSAQLQILTSTES 705
Cdd:TIGR02168 223 RELELALLVLRlEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELeeeieelQKELYALANEISRLEQ 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 706 QLKEVRSQHSRCVQDLAVKDELLCQLTQSN---KEQATQWQKEEMELKHIQAELLQQQAVLAKEVQDLRETVEFIDEESQ 782
Cdd:TIGR02168 303 QKQILRERLANLERQLEELEAQLEELESKLdelAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLE 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 783 VAHRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTEAKHEKQALEKTHQHSQELRLLAEQLQSLTLFLQAK 862
Cdd:TIGR02168 383 TLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEA 462
|
250 260
....*....|....*....|....*..
gi 33859674 863 LKENKAESEIILPSTGSAPAQEHPLSN 889
Cdd:TIGR02168 463 LEELREELEEAEQALDAAERELAQLQA 489
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
634-872 |
1.56e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.81 E-value: 1.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 634 RELTKKLTAKSRQALQERDAAIEEKKQVVK-EVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQiltstesQLKEVRS 712
Cdd:COG1196 223 KELEAELLLLKLRELEAELEELEAELEELEaELEELEAELAELEAELEELRLELEELELELEEAQA-------EEYELLA 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 713 QHSRCVQDLAVKDELLCQLTQSNKEQATQWQKEEMELKHIQAELLQQQAVLAKEVQDLRETVEFIDEESQVAHRELGQIE 792
Cdd:COG1196 296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 793 SQLKVTLELLRERslqcETLRDTVDSLRAELASTEAKHEKQALEKTHQHSQELRLLAEQLQSLTLFLQAKLKENKAESEI 872
Cdd:COG1196 376 EAEEELEELAEEL----LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
521-1053 |
2.09e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.42 E-value: 2.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 521 LKKLKAKLQSLKTEceEARHSKEMALKGKAAAEAVLEAFRAHASQRISQLEQGLTSMQEFRGLLQEAQTQLIGLHTEQKE 600
Cdd:COG1196 222 LKELEAELLLLKLR--ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 601 LAQQ---TVSLSSALQQDWTSVQLNYGIWAALLSWSRELTKKLTAKSRQALQERDAAIEEKKQVVKEVEQVSAHLEDCKG 677
Cdd:COG1196 300 LEQDiarLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 678 QIEQLKLENSRLTADLSAQLQILTSTESQLKEVRSQHSRCVQDLAVKDELLcqltQSNKEQATQWQKEEMELKHIQAELL 757
Cdd:COG1196 380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEAL----AELEEEEEEEEEALEEAAEEEAELE 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 758 QQQAVLAKEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELAStEAKHEKQALEK 837
Cdd:COG1196 456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA-GAVAVLIGVEA 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 838 THQHSQELRLLAEQLQSLT------LFLQAKLKENKAESEIILPSTGSAPAQEHPLSNDSSISEQTP-TAAVDEVPEPAP 910
Cdd:COG1196 535 AYEAALEAALAAALQNIVVeddevaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVdLVASDLREADAR 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 911 VPLLGSVKSAFTRVA----SMASFQPTETPDLEKSLAEMSTVLQ----------ELKSLCSLLQESKEEATGVLQREI-- 974
Cdd:COG1196 615 YYVLGDTLLGRTLVAarleAALRRAVTLAGRLREVTLEGEGGSAggsltggsrrELLAALLEAEAELEELAERLAEEEle 694
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 975 -CELHSRLQAQEE---EHQEALKAKEADMEKLNQALCLLRKNEKELLEVIQKQNEKILGQIDKSGQLIN-LREEVTQLTQ 1049
Cdd:COG1196 695 lEEALLAEEEEERelaEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEeLERELERLER 774
|
....
gi 33859674 1050 SLRR 1053
Cdd:COG1196 775 EIEA 778
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
564-854 |
8.26e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 66.62 E-value: 8.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 564 SQRISQLEQGLTSMQEfrgLLQEAQTQLIGLHTEQKELAQQTVSLSSALQQDWTSVQLNYgiwaALLSWSRELTKKLTAK 643
Cdd:TIGR02168 676 RREIEELEEKIEELEE---KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALR----KDLARLEAEVEQLEER 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 644 SRQALQERDAAIEEKKQVVKEVEQVSAHLEDCKGQIEQLKLEnsrlTADLSAQLQILtstESQLKEVRSQHSRCVQDLAV 723
Cdd:TIGR02168 749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ----IEQLKEELKAL---REALDELRAELTLLNEEAAN 821
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 724 KDELLcqltQSNKEQATQWQKEEMELKHIQAELLQQQAVLAKEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLR 803
Cdd:TIGR02168 822 LRERL----ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELE 897
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 33859674 804 ERSLQCETLRDTVDSLRAELASTEAKHEKQALEKthqhsQELRLLAEQLQS 854
Cdd:TIGR02168 898 ELSEELRELESKRSELRRELEELREKLAQLELRL-----EGLEVRIDNLQE 943
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
646-1063 |
1.14e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 62.48 E-value: 1.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 646 QALQERDAAIEEKKQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQILtstesQLKEVRSQHSRCVQDLAVKD 725
Cdd:COG4717 71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL-----QLLPLYQELEALEAELAELP 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 726 ELLCQLtqsnKEQATQWQKEEMELKHIQAELLQQQAVLAKEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLRER 805
Cdd:COG4717 146 ERLEEL----EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEE 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 806 slqcetlrdtVDSLRAELASTEAKHEKQALEKTHQHSQELRLLAEQLQSLTLFLQAKLKENKAESEIILPSTGSAPAQEH 885
Cdd:COG4717 222 ----------LEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFL 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 886 PLSNdssiSEQTPTAAVDEVPEPAPVPLLGS--VKSAFTRVASMASFQPTETPDLEKSLAEMSTVLQELKSLCS--LLQE 961
Cdd:COG4717 292 LLAR----EKASLGKEAEELQALPALEELEEeeLEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEelQLEE 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 962 SKEEATGVLQREICELHSRLQAQEEEHQEALKAKEAdMEKLNQALCLLRKNEKELLEVIQKQN-EKILGQIDKsgQLINL 1040
Cdd:COG4717 368 LEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEE-LEELEEQLEELLGELEELLEALDEEElEEELEELEE--ELEEL 444
|
410 420
....*....|....*....|...
gi 33859674 1041 REEVTQLTQSLRRAETETKVLQE 1063
Cdd:COG4717 445 EEELEELREELAELEAELEQLEE 467
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
521-1138 |
2.58e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 61.61 E-value: 2.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 521 LKKLKAKLQSLKTECEEARHSKEMALKGKAAAEAVLEAFRAhasqRISQLEQgltsmqefrgLLQEAQTQLIGLHTEQKE 600
Cdd:TIGR02168 234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL----EVSELEE----------EIEELQKELYALANEISR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 601 LAQQTVSLSSALQQDWTSvqlnygiwaaLLSWSRELTKKLtaKSRQALQERDAAIEEKKQVVK-EVEQVSAHLEDCKGQI 679
Cdd:TIGR02168 300 LEQQKQILRERLANLERQ----------LEELEAQLEELE--SKLDELAEELAELEEKLEELKeELESLEAELEELEAEL 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 680 EQLKLENSRLTADLSAQLQILTSTESQLKEVRSQHSRCVQDLAVKDELLCQLTQSNKEQATQWQKEEM--------ELKH 751
Cdd:TIGR02168 368 EELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELkelqaeleELEE 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 752 IQAELLQQQAVLAKEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLRERS----------LQCETLRDTVDSLrA 821
Cdd:TIGR02168 448 ELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkallKNQSGLSGILGVL-S 526
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 822 ELASTEAKHEKqALEKThqhsqelrlLAEQLQSLT-------LFLQAKLKENKAESEIILPSTGSAPAqeHPLSNDSSIS 894
Cdd:TIGR02168 527 ELISVDEGYEA-AIEAA---------LGGRLQAVVvenlnaaKKAIAFLKQNELGRVTFLPLDSIKGT--EIQGNDREIL 594
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 895 EQTP---TAAVDEVPEPAPVPLL-----------------------------------------GSVKSAFTRVASMASF 930
Cdd:TIGR02168 595 KNIEgflGVAKDLVKFDPKLRKAlsyllggvlvvddldnalelakklrpgyrivtldgdlvrpgGVITGGSAKTNSSILE 674
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 931 QPTETPDLEKSLAEM-------STVLQELKSLCSLLQESKEEATGVLQ---REICELHSRLQAQEEEHQ----------E 990
Cdd:TIGR02168 675 RRREIEELEEKIEELeekiaelEKALAELRKELEELEEELEQLRKELEelsRQISALRKDLARLEAEVEqleeriaqlsK 754
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 991 ALKAKEADMEKLNQALCLLRKNEKELLEVIQKQNEKILGQIDKSGQLI----NLREEVTQLTQSLRRAETETKVLQEALE 1066
Cdd:TIGR02168 755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRealdELRAELTLLNEEAANLRERLESLERRIA 834
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 33859674 1067 gqldpSCQLMATNWIQEKVFLSQEVSKLRVMFLEMKTEKEQLMDKYLSH---RHILEENLRRSDTELKKLDDTIQ 1138
Cdd:TIGR02168 835 -----ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALlneRASLEEALALLRSELEELSEELR 904
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
558-1140 |
4.80e-09 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 60.75 E-value: 4.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 558 AFRAHASQRISQLEQGLTSMQEFRGLLQEAQTQLIGLHTEQKELAQQTVSLSSALQQDWTSVQLNYGIWAALLSWSRELT 637
Cdd:TIGR00618 156 QFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREAL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 638 KKlTAKSRQALQERDAAIEEKKQVVKEVEQVSAHLEDCKGQIEQLKLENSRLtaDLSAQLQILTSTESQLKEVRSQHSRC 717
Cdd:TIGR00618 236 QQ-TQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERI--NRARKAAPLAAHIKAVTQIEQQAQRI 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 718 VQDLAVKDELLCQL---------------TQSNKEQATQWQKEEMELKHIQA----ELLQQQAVLAKEVQDLRETVEFID 778
Cdd:TIGR00618 313 HTELQSKMRSRAKLlmkraahvkqqssieEQRRLLQTLHSQEIHIRDAHEVAtsirEISCQQHTLTQHIHTLQQQKTTLT 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 779 EESQVAHRELGQI-ESQLKVTLELLRERSLQC--------ETLRDTVDSLRAELASTEAKHEKQALEKTHQHSQELRLLA 849
Cdd:TIGR00618 393 QKLQSLCKELDILqREQATIDTRTSAFRDLQGqlahakkqQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKERE 472
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 850 EQLQSLTLFLQaKLKENKAESEIILPSTgsapaQEHPLSNDSSISEQTPTAAVDEVPEPAPVPLLG---SVKSAFTRVAS 926
Cdd:TIGR00618 473 QQLQTKEQIHL-QETRKKAVVLARLLEL-----QEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRgeqTYAQLETSEED 546
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 927 MASFQPTETPDLEKSLAEMSTVLQELKSLCSLLQESKEEATGVLQrEICELHSRLQAQEEEHQEALKAKEADMEKLNQAL 1006
Cdd:TIGR00618 547 VYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQN-ITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQ 625
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 1007 CLLRKnekeLLEVIQKQNEKILGQIDKSGQLINLREEVTQLTQSLRRAETETKVLQEALEGQLDPSCQLMATNWIQEkvf 1086
Cdd:TIGR00618 626 DLQDV----RLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEM--- 698
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 33859674 1087 LSQEVSKLRvmflemktEKEQLMDKYLSHRHILEENLRRSDTELKKLDDTIQHV 1140
Cdd:TIGR00618 699 LAQCQTLLR--------ELETHIEEYDREFNEIENASSSLGSDLAAREDALNQS 744
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
656-1152 |
1.13e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 59.68 E-value: 1.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 656 EEKKQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQILTSTESQLKEVRSQHSRC---VQDLAVKDELLCQ-- 730
Cdd:TIGR00606 405 DEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLegsSDRILELDQELRKae 484
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 731 --LTQSNKEQATQ-WQKEEMELKHIQAELLQQQAVLAKEVQDL------RETVEFIDEESQVAHRELGQIESQLKVTLEL 801
Cdd:TIGR00606 485 reLSKAEKNSLTEtLKKEVKSLQNEKADLDRKLRKLDQEMEQLnhhtttRTQMEMLTKDKMDKDEQIRKIKSRHSDELTS 564
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 802 LRERSLQCETLRDTVDSLRAELASTEAKHEKQALE------KTHQHSQELRLLAEQLQSLT--LFLQAKLKENKAESEII 873
Cdd:TIGR00606 565 LLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKElasleqNKNHINNELESKEEQLSSYEdkLFDVCGSQDEESDLERL 644
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 874 LPSTGSAPAQEHPLSNDSSISEQTPTAAVDEVPEPAPVpllgsVKSAFTRVASMASFqpteTPDLEKSLAEMSTVLQELK 953
Cdd:TIGR00606 645 KEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPV-----CQRVFQTEAELQEF----ISDLQSKLRLAPDKLKSTE 715
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 954 SLCSLLQESKEEATGV----------LQREICELHSRLQAQEEEHQEA---LKAKEADMEKLNQAL-----CLLRKNEKE 1015
Cdd:TIGR00606 716 SELKKKEKRRDEMLGLapgrqsiidlKEKEIPELRNKLQKVNRDIQRLkndIEEQETLLGTIMPEEesakvCLTDVTIME 795
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 1016 LLEVIQKQNEKILGQIDKSGQLINLREEVTQLTQSLRRAETETKVLQEalEGQLDPSCqlmatnwIQEKvflSQEVSKLR 1095
Cdd:TIGR00606 796 RFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVS--KIELNRKL-------IQDQ---QEQIQHLK 863
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 33859674 1096 VMFLEMKTEKEQLMDKyLSHRHILEENLRRSDTELKKLDDTIQHVYETLLSIPETMK 1152
Cdd:TIGR00606 864 SKTNELKSEKLQIGTN-LQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLE 919
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
642-868 |
2.05e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.91 E-value: 2.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 642 AKSRQALQERDAAIEEKKQVVKEVE----QVSAHLEDCKGQIEQLKLENSRLTADLSAQLQILTSTESQLKEVRSQHSRC 717
Cdd:TIGR02168 666 AKTNSSILERRREIEELEEKIEELEekiaELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 718 VQDLAVKDELLCQLTQSNKEQATQWQKEEMELKHIQAELLQQQAVLA----------KEVQDLRETVEFIDEESQVAHRE 787
Cdd:TIGR02168 746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEqlkeelkalrEALDELRAELTLLNEEAANLRER 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 788 LGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTEAKHEKQALEKTH------QHSQELRLLAEQLQSLTLFLQA 861
Cdd:TIGR02168 826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAllneraSLEEALALLRSELEELSEELRE 905
|
....*..
gi 33859674 862 KLKENKA 868
Cdd:TIGR02168 906 LESKRSE 912
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
637-829 |
2.56e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.47 E-value: 2.56e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 637 TKKLTAKSRQALQERDAAIEEKKQVVKEVEQVSAHLEDckgQIEQLKLENSRLTADLSAQLQIL---------TSTESQL 707
Cdd:COG4942 46 LKKEEKALLKQLAALERRIAALARRIRALEQELAALEA---ELAELEKEIAELRAELEAQKEELaellralyrLGRQPPL 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 708 KEVRSQHSrcVQDLAVKDELLCQLTQSNKEQATQWQKEEMELKHIQAELLQQQAVLAKEVQDLRETVEFIDEESQVAHRE 787
Cdd:COG4942 123 ALLLSPED--FLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKL 200
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 33859674 788 LGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTEAK 829
Cdd:COG4942 201 LARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
550-1070 |
1.43e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 56.08 E-value: 1.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 550 AAAEAVLEAFrahasQRISQLEQGLTSMQEFRGLLQEAQtQLIGLHTEQKELAQQTVSLSSALQQdWTSvQLNYGIWAAL 629
Cdd:COG4913 225 EAADALVEHF-----DDLERAHEALEDAREQIELLEPIR-ELAERYAAARERLAELEYLRAALRL-WFA-QRRLELLEAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 630 LSWSRELTKKLTAKSRQALQERDAAIEEKKQVVKEVEQVS-AHLEDCKGQIEQLKLENSRLTADLSAQLQILTS------ 702
Cdd:COG4913 297 LEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLEALLAAlglplp 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 703 -TESQLKEVRSQHSRCVQDLAVKDELLCQLTQSNKEQATQWQKEEMELKHIQAELLQQQAVLAKEVQDLRETVEfidees 781
Cdd:COG4913 377 aSAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALA------ 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 782 qvahRELGQIESQLKVTLELLrERSLQCETLRDTVDSLRAELAST---EAKHEKQALEKTHQHSQELRLLAEqlqsltlf 858
Cdd:COG4913 451 ----EALGLDEAELPFVGELI-EVRPEEERWRGAIERVLGGFALTllvPPEHYAAALRWVNRLHLRGRLVYE-------- 517
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 859 lqaKLKENKAESEIILPSTGSAPAQ----EHPLSN--DSSISEQTPTAAVDEVPE----PAPVPLLGSVKSAFTRVASMA 928
Cdd:COG4913 518 ---RVRTGLPDPERPRLDPDSLAGKldfkPHPFRAwlEAELGRRFDYVCVDSPEElrrhPRAITRAGQVKGNGTRHEKDD 594
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 929 SFQPTETP------------------DLEKSLAEMSTVLQELKSLCSLLQESKEEATGVLQR-----EICELHSRLQAQE 985
Cdd:COG4913 595 RRRIRSRYvlgfdnraklaaleaelaELEEELAEAEERLEALEAELDALQERREALQRLAEYswdeiDVASAEREIAELE 674
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 986 EEHQEALKAKeADMEKLNQALCLLRKNEKELLEVIQKQNEKIlGQIDKsgQLINLREEVTQLTQSLRRAETETKV-LQEA 1064
Cdd:COG4913 675 AELERLDASS-DDLAALEEQLEELEAELEELEEELDELKGEI-GRLEK--ELEQAEEELDELQDRLEAAEDLARLeLRAL 750
|
....*.
gi 33859674 1065 LEGQLD 1070
Cdd:COG4913 751 LEERFA 756
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
765-1065 |
1.52e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.83 E-value: 1.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 765 KEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTEAKHEkQALEKTHQHSQE 844
Cdd:TIGR02168 677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE-QLEERIAQLSKE 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 845 LRLLAEQLQSLTLFL---QAKLKENKAESEiilpsTGSAPAQEHPLSNDSSISEqtptaavdevpepapvplLGSVKSAF 921
Cdd:TIGR02168 756 LTELEAEIEELEERLeeaEEELAEAEAEIE-----ELEAQIEQLKEELKALREA------------------LDELRAEL 812
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 922 TRVASMASFQPTETPDLEKSLAEMSTVLQELKSLCSLLQESKEEATGVLqreicelhSRLQAQEEEHQEALKAKEADMEK 1001
Cdd:TIGR02168 813 TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI--------EELEELIEELESELEALLNERAS 884
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 33859674 1002 LNQALCLLRKNEKELLEVIQKQNEKILgqiDKSGQLINLREEVTQLTQSLRRAETETKVLQEAL 1065
Cdd:TIGR02168 885 LEEALALLRSELEELSEELRELESKRS---ELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
521-731 |
1.19e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.07 E-value: 1.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 521 LKKLKAKLQSLKTECEEARHSKEMALKGKAAAEAVLEAFR---AHASQRISQLEQGLTSMQEFRGLLQEAQTQLIG-LHT 596
Cdd:COG4942 22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALErriAALARRIRALEQELAALEAELAELEKEIAELRAeLEA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 597 EQKELAQQTVSLSSALQQDWTSVQLNYGIWAALLSWSRELtkkltaksRQALQERDAAIEEKKQVVKEVEQVSAHLEDCK 676
Cdd:COG4942 102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYL--------KYLAPARREQAEELRADLAELAALRAELEAER 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 33859674 677 GQIEQLKLENSRLTADLSAQLQILTSTESQLKEVRSQHSRCVQDLAVKDELLCQL 731
Cdd:COG4942 174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
532-1159 |
1.58e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 52.81 E-value: 1.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 532 KTECEEARHSKEMALKGKAAAEAVLEAFrahaSQRISQLEQGLTSMQEF--------RGLLQEAQTQLIGLHTEQKELA- 602
Cdd:pfam15921 56 KYEVELDSPRKIIAYPGKEHIERVLEEY----SHQVKDLQRRLNESNELhekqkfylRQSVIDLQTKLQEMQMERDAMAd 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 603 ------QQTVSLSSALQQDWTSVQLNYGIWAALLSWSRELTKKLtaksRQALQERDAAIEEKKQVVKEVEQVSA---HLE 673
Cdd:pfam15921 132 irrresQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQL----RKMMLSHEGVLQEIRSILVDFEEASGkkiYEH 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 674 DCKGQI--EQLKLENSRLTADLSAQLQILTS----TESQLKEVRSQHSRcvqdlavKDELLCQLTQSNKEQATQwqKEEM 747
Cdd:pfam15921 208 DSMSTMhfRSLGSAISKILRELDTEISYLKGrifpVEDQLEALKSESQN-------KIELLLQQHQDRIEQLIS--EHEV 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 748 ELkhiqAELLQQQAVLAKEVQDLRETVEFIDEESQ----VAHRELGQIESQLKVTLELLRERSlqcETLRDTVDSLRAEL 823
Cdd:pfam15921 279 EI----TGLTEKASSARSQANSIQSQLEIIQEQARnqnsMYMRQLSDLESTVSQLRSELREAK---RMYEDKIEELEKQL 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 824 AS-----TEAKHEKQalekthQHSQELRLLAEQLQSLTLFLQAKLKENKAESE----IILPSTGSAPAQEHPLS--NDSS 892
Cdd:pfam15921 352 VLanselTEARTERD------QFSQESGNLDDQLQKLLADLHKREKELSLEKEqnkrLWDRDTGNSITIDHLRRelDDRN 425
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 893 ISEQTPTAAVDEVP-------EPAPVPLLGSVKSaFTRVASMASFQPTETPDLEKSLAEMSTVLQELKS-------LCSL 958
Cdd:pfam15921 426 MEVQRLEALLKAMKsecqgqmERQMAAIQGKNES-LEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESsertvsdLTAS 504
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 959 LQEsKEEATGVLQREICELHSR--LQAQEEEHQEALKAKEADMEKLNQALCLLRKNEKELLEVIQKQNEKILGQIDKSGQ 1036
Cdd:pfam15921 505 LQE-KERAIEATNAEITKLRSRvdLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGR 583
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 1037 LIN-LREEVTQLTQSL--RRAE-TETKVLQEALEGQLDpSCQLMATNWIQEKVFLSQEVSKLRVMFLEMKTEKEQLMDKY 1112
Cdd:pfam15921 584 TAGaMQVEKAQLEKEIndRRLElQEFKILKDKKDAKIR-ELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEV 662
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*...
gi 33859674 1113 LSHRH----------ILEENLRRSDTELKKLDDTIQHVYETLLS-IPETMKSCKELQG 1159
Cdd:pfam15921 663 KTSRNelnslsedyeVLKRNFRNKSEEMETTTNKLKMQLKSAQSeLEQTRNTLKSMEG 720
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
685-1059 |
1.90e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 1.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 685 ENSRLTADLSAQLQILTSTESQLKEVRSQHSRCVQDLAVKDELLCQLTQSNKEQATQWQKEEMElkhiQAELLQQQAVLA 764
Cdd:TIGR02168 678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAE----VEQLEERIAQLS 753
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 765 KEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTEAKHEKQAlEKTHQHSQE 844
Cdd:TIGR02168 754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR-ERLESLERR 832
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 845 LRLLAEQLQSLtlflqAKLKENKAESEIILpstgsapAQEHplsNDSSISEQTPTAAVDEvpepapvpLLGSVKSAFTRV 924
Cdd:TIGR02168 833 IAATERRLEDL-----EEQIEELSEDIESL-------AAEI---EELEELIEELESELEA--------LLNERASLEEAL 889
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 925 ASMASfqptETPDLEKSLAEMSTVLQELKSLCSLLQESKEEATGVLQR---EICELHSRLQAQ---EEEHQEALKAK-EA 997
Cdd:TIGR02168 890 ALLRS----ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGlevRIDNLQERLSEEyslTLEEAEALENKiED 965
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 33859674 998 DMEKLNQALCLLRKNEKEL-------LEVIQKQNEKilgQIDKSGQLINLREEVTQLTQSLRRAETETK 1059
Cdd:TIGR02168 966 DEEEARRRLKRLENKIKELgpvnlaaIEEYEELKER---YDFLTAQKEDLTEAKETLEEAIEEIDREAR 1031
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
736-1144 |
2.48e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 51.69 E-value: 2.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 736 KEQATQWQKEEMELKHIQAELlqqqAVLAKEVQDLRETVEFIDEESQV--AHRELGQIESQLK---VTLELLRERSLQCE 810
Cdd:COG4717 84 EEKEEEYAELQEELEELEEEL----EELEAELEELREELEKLEKLLQLlpLYQELEALEAELAelpERLEELEERLEELR 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 811 TLRDTVDSLRAELASTEAKHEKQALEKTHQHSQELRLLAEQLQSLTL---FLQAKLKENKAESEIILPSTGSAPAQEHPL 887
Cdd:COG4717 160 ELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQrlaELEEELEEAQEELEELEEELEQLENELEAA 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 888 SNDSSISEQTPTAAVdevpepapvplLGSVKSAFTRVASMASFQPTETPDLEKSLAEMSTVLQELKSLCSLLQESKEEAT 967
Cdd:COG4717 240 ALEERLKEARLLLLI-----------AAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQ 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 968 G------VLQREICELHSRLQAQEEEHQEALKAKEADMEKLNQALCLLRKNEKEL-LEVIQKQNEKILGQIDkSGQLINL 1040
Cdd:COG4717 309 AlpaleeLEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELqLEELEQEIAALLAEAG-VEDEEEL 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 1041 REEVTQLtQSLRRAETETKVLQEALEGQLDPSCQLMATnwiQEKVFLSQEVSKLRVMFLEMKTEKEQLMDKYLSHRHILE 1120
Cdd:COG4717 388 RAALEQA-EEYQELKEELEELEEQLEELLGELEELLEA---LDEEELEEELEELEEELEELEEELEELREELAELEAELE 463
|
410 420
....*....|....*....|....
gi 33859674 1121 EnlRRSDTELKKLDDTIQHVYETL 1144
Cdd:COG4717 464 Q--LEEDGELAELLQELEELKAEL 485
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
505-1111 |
5.06e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 51.12 E-value: 5.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 505 QESQRSKTLVSSCSRVLKKLKAKLQSLKTEceEARHSKEMALKGKAAAEAVLEAFRAHASQRISQLEQGLTSMQEFRGLL 584
Cdd:TIGR00618 246 TQKREAQEEQLKKQQLLKQLRARIEELRAQ--EAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSR 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 585 QEAQTQLIGLHTEQKELAQQTVSLSSALQQ-----DWTSVQLNygiWAALLSWSRELTKKLTAKSRQ---ALQERDAAIE 656
Cdd:TIGR00618 324 AKLLMKRAAHVKQQSSIEEQRRLLQTLHSQeihirDAHEVATS---IREISCQQHTLTQHIHTLQQQkttLTQKLQSLCK 400
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 657 EKKQVVKEVEQVSA----------HLEDCKGQIEQLKLENSRLTADLSAQLQILTSTESQLKEVRSQHSRCVQDLAVKDE 726
Cdd:TIGR00618 401 ELDILQREQATIDTrtsafrdlqgQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQ 480
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 727 LLCQLTQSNKEQAtqwqKEEMELKHIQAELLQQQAVLAKEVQDLretvefidEESQVAHRELGQIESQLKVTLELLRERS 806
Cdd:TIGR00618 481 IHLQETRKKAVVL----ARLLELQEEPCPLCGSCIHPNPARQDI--------DNPGPLTRRMQRGEQTYAQLETSEEDVY 548
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 807 LQCETLRDTVDSLRAELasTEAKHEKQALEkthQHSQELRLLAEQLQSLTLFLQAKLKEN-KAESEIILPSTGSAPAQEH 885
Cdd:TIGR00618 549 HQLTSERKQRASLKEQM--QEIQQSFSILT---QCDNRSKEDIPNLQNITVRLQDLTEKLsEAEDMLACEQHALLRKLQP 623
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 886 PLSNDSSISEQTPTAAVDEVPEPAPVPLLGSVKSAFTRVASMASFQPTE--------TPDLEKSLAEMSTVLQELKSLCS 957
Cdd:TIGR00618 624 EQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKellasrqlALQKMQSEKEQLTYWKEMLAQCQ 703
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 958 LLQESKEEATGVLQREICELH-------SRLQAQEEEHQEALKAKEADMEKLNQALCLL--RKNEKELLEVIQKQNEKil 1028
Cdd:TIGR00618 704 TLLRELETHIEEYDREFNEIEnassslgSDLAAREDALNQSLKELMHQARTVLKARTEAhfNNNEEVTAALQTGAELS-- 781
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 1029 gqiDKSGQLINLREEVTQLTQSLRRAETETKVLQEALEGQLDPSCQLMAT------NWIQEKVFLSQEVSKLRVMFLEMK 1102
Cdd:TIGR00618 782 ---HLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQeeeqflSRLEEKSATLGEITHQLLKYEECS 858
|
....*....
gi 33859674 1103 TEKEQLMDK 1111
Cdd:TIGR00618 859 KQLAQLTQE 867
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
779-1027 |
8.34e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.38 E-value: 8.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 779 EESQVAHRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTEAKHekQALEKT-HQHSQELRLLAEQLQSLTL 857
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRI--RALEQElAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 858 FLQAkLKENKAESEIILPSTGSAPAQEHPLSNDSsiseqtptaavdevpepapvpllgsVKSAFTRVASMASFqpteTPD 937
Cdd:COG4942 98 ELEA-QKEELAELLRALYRLGRQPPLALLLSPED-------------------------FLDAVRRLQYLKYL----APA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 938 LEKSLAEMSTVLQELKSLCSLLQESKEEATgVLQREICELHSRLQAQEEEHQEALKAKEADMEKLNQALCLLRKNEKELL 1017
Cdd:COG4942 148 RREQAEELRADLAELAALRAELEAERAELE-ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226
|
250
....*....|
gi 33859674 1018 EVIQKQNEKI 1027
Cdd:COG4942 227 ALIARLEAEA 236
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
521-1043 |
1.24e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 49.68 E-value: 1.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 521 LKKLKAKLQSLKTECEEARHSKEMALKGKAAAEAVL---EAFRAHASQRISQLEQGLTSMQEFRGLlQEAQTQLIGLHTE 597
Cdd:PRK03918 226 LEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIrelEERIEELKKEIEELEEKVKELKELKEK-AEEYIKLSEFYEE 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 598 QKELAQQTVSLSSALQQDWTSVQLNYGIWAALLSWSRELTKKL--TAKSRQALQERDAAIEEKKQVVKEVEQVSAHL--- 672
Cdd:PRK03918 305 YLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLkeLEKRLEELEERHELYEEAKAKKEELERLKKRLtgl 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 673 --EDCKGQIEQLKLENSRLTADLSAqlqiLTSTESQLKEVRSQHSRCVQDLAvKDELLCQLTqsnkeqatqwqKEEMELK 750
Cdd:PRK03918 385 tpEKLEKELEELEKAKEEIEEEISK----ITARIGELKKEIKELKKAIEELK-KAKGKCPVC-----------GRELTEE 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 751 HiQAELLQQqavLAKEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLRERSL--QCETLRDTVDSLRAELASTEA 828
Cdd:PRK03918 449 H-RKELLEE---YTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELaeQLKELEEKLKKYNLEELEKKA 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 829 KHEKQALEKTHQHSQELRLLAEQLQsltlflqaKLKENKAESEIILPSTGSApaqEHPLSNDSSISEQTPTAAVDEVP-- 906
Cdd:PRK03918 525 EEYEKLKEKLIKLKGEIKSLKKELE--------KLEELKKKLAELEKKLDEL---EEELAELLKELEELGFESVEELEer 593
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 907 ----EPAPVPLLgSVKSAFTRVASMASFQPTETPDLEKSLAEMSTVLQELKSLCSLLQE-----SKEEATGVLQR--EIC 975
Cdd:PRK03918 594 lkelEPFYNEYL-ELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEElekkySEEEYEELREEylELS 672
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 33859674 976 ELHSRLQAQEEEHQEALKAKEADMEKLNQALCLLRKNEKElLEVIQKQNEKILGQIDKSGQLINLREE 1043
Cdd:PRK03918 673 RELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKE-LEKLEKALERVEELREKVKKYKALLKE 739
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
531-855 |
1.30e-05 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 49.67 E-value: 1.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 531 LKTECEEARHSKEMAlkGKAAAEAVLEAFRAHASQRISQ--LEQGLTSMQEFRGLLQEAQTQLIGLHTEQK--------- 599
Cdd:PRK10929 28 ITQELEQAKAAKTPA--QAEIVEALQSALNWLEERKGSLerAKQYQQVIDNFPKLSAELRQQLNNERDEPRsvppnmstd 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 600 ELAQQTVSLSSalqqdwtsvqlnygiwaallswsreltkKLTAKSRQALQERDAAIEekkqvvkeveqvsahLEDCKGQI 679
Cdd:PRK10929 106 ALEQEILQVSS----------------------------QLLEKSRQAQQEQDRARE---------------ISDSLSQL 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 680 EQLKLENSRLTADLSAQLQILTSTESQLKEVR--SQHSRCVQDLAVKDEL-LCQLTQSNKEqatqwqkeemELKHIQAEL 756
Cdd:PRK10929 143 PQQQTEARRQLNEIERRLQTLGTPNTPLAQAQltALQAESAALKALVDELeLAQLSANNRQ----------ELARLRSEL 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 757 LQQQAV-LAKEVQDLRETVEFidEESQVAHRELGQIESQLKVTLELLRERSLQCETLRDTVDSL--RAELASTEAKHEKQ 833
Cdd:PRK10929 213 AKKRSQqLDAYLQALRNQLNS--QRQREAERALESTELLAEQSGDLPKSIVAQFKINRELSQALnqQAQRMDLIASQQRQ 290
|
330 340
....*....|....*....|..
gi 33859674 834 ALEKTHQHSQELRLLAEQLQSL 855
Cdd:PRK10929 291 AASQTLQVRQALNTLREQSQWL 312
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
506-1138 |
1.32e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.68 E-value: 1.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 506 ESQRSKTL--VSSCSRVLKKLKAKLQSLKTECEEARHS-KEMALKGKAAAEAVLEAFRAHASQRISQLEQGLTSMQEFRG 582
Cdd:TIGR02169 236 ERQKEAIErqLASLEEELEKLTEEISELEKRLEEIEQLlEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKER 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 583 LLQEAQTQLIGLHTEQKELAQQTVSLSSALQQdwtsvqlnygiWAALL-SWSRELTKKLT--AKSRQALQERDAAIEEKK 659
Cdd:TIGR02169 316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEE-----------ERKRRdKLTEEYAELKEelEDLRAELEEVDKEFAETR 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 660 QVVKEVEQvsaHLEDCKGQIEQLKLENSRLtadlsaqlqiltstESQLKEVRSQHSRCVQDLAVKDELLCQLTQSNKEQA 739
Cdd:TIGR02169 385 DELKDYRE---KLEKLKREINELKRELDRL--------------QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKA 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 740 TQWQKEEMELKHIQAELLQQQavlaKEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLRERSLQCETLRDTVD-- 817
Cdd:TIGR02169 448 LEIKKQEWKLEQLAADLSKYE----QELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgv 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 818 -SLRAELASTEAKHEKqALE-----KTHQHSQELRLLAEQLQSLtlflqakLKENKAESEIILPSTGSAPAQEHP--LSN 889
Cdd:TIGR02169 524 hGTVAQLGSVGERYAT-AIEvaagnRLNNVVVEDDAVAKEAIEL-------LKRRKAGRATFLPLNKMRDERRDLsiLSE 595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 890 DSSISeqtptAAVDEV---PEPAPV------------------PLLGSVK------------SAFTRVASMASFQPTETP 936
Cdd:TIGR02169 596 DGVIG-----FAVDLVefdPKYEPAfkyvfgdtlvvedieaarRLMGKYRmvtlegelfeksGAMTGGSRAPRGGILFSR 670
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 937 DLEKSLAEMSTVLQELKSLCSLLQESKEEATG----------VLQREICELHSRLQAQEEEHQ---EALKAKEADMEKLN 1003
Cdd:TIGR02169 671 SEPAELQRLRERLEGLKRELSSLQSELRRIENrldelsqelsDASRKIGEIEKEIEQLEQEEEklkERLEELEEDLSSLE 750
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 1004 QALCLLRKNEKELLEVIQKQNEKI---------------LGQIDKSGQLIN-LREEVTQLTQSLRRAETETKVLQ---EA 1064
Cdd:TIGR02169 751 QEIENVKSELKELEARIEELEEDLhkleealndlearlsHSRIPEIQAELSkLEEEVSRIEARLREIEQKLNRLTlekEY 830
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 33859674 1065 LEGQLDPSCQLMATNWIQEKVFLSQ-EVSKLRVMFLEMKTEKEQLMDKYLSHRHI-LEENLRRSDTELKKLDDTIQ 1138
Cdd:TIGR02169 831 LEKEIQELQEQRIDLKEQIKSIEKEiENLNGKKEELEEELEELEAALRDLESRLGdLKKERDELEAQLRELERKIE 906
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
565-1165 |
1.59e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 49.45 E-value: 1.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 565 QRISQLEQGLTSMQEFRGLLQEAQTQLIGLHTEQKELAQQTVSLSSALQQDWTSV--QLNYGIWAALLSWSRElTKKLTA 642
Cdd:pfam12128 248 QEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKrdELNGELSAADAAVAKD-RSELEA 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 643 KSRQALQERDAAIEEKK-------QVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQ-----ILTSTESQLKEV 710
Cdd:pfam12128 327 LEDQHGAFLDADIETAAadqeqlpSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNrdiagIKDKLAKIREAR 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 711 RSQHSRCVQDL-----AVKDELLCQLTQSNKEQ-----ATQWQKEEMELKHIQAELLQQQAVLAKEVQDLRETVEFIDEE 780
Cdd:pfam12128 407 DRQLAVAEDDLqalesELREQLEAGKLEFNEEEyrlksRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAANAE 486
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 781 SQVAHRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELA----------STEAKHEKQALEK------------- 837
Cdd:pfam12128 487 VERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFpqagtllhflRKEAPDWEQSIGKvispellhrtdld 566
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 838 ----THQHSQEL-----RLLAEQLQ-SLTLFLQAKLKENKAESEIILPSTGSAPAQehplsndssISEQTPTAAVD-EVP 906
Cdd:pfam12128 567 pevwDGSVGGELnlygvKLDLKRIDvPEWAASEEELRERLDKAEEALQSAREKQAA---------AEEQLVQANGElEKA 637
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 907 EPAPVPLLGSVKSAFTRVASMASFQPTETPDLEKSLAE--------MSTVLQELKSLCSLLQESKEEatgvLQREICELH 978
Cdd:pfam12128 638 SREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAErkdsanerLNSLEAQLKQLDKKHQAWLEE----QKEQKREAR 713
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 979 SRLQAQEEEHQEALKAKEAdmeKLNQALCLLRKNEKELLEVIQKQNEKILGQIDKSGQ-LINLREEVTQLTQSLRRAEte 1057
Cdd:pfam12128 714 TEKQAYWQVVEGALDAQLA---LLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDvIAKLKREIRTLERKIERIA-- 788
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 1058 tKVLQEALEGQldpscQLMATNWIQEKVFLSQEVSKLRVMFLEMK-------TEKEQLMDKYLSHRHILEENLRRSDTEL 1130
Cdd:pfam12128 789 -VRRQEVLRYF-----DWYQETWLQRRPRLATQLSNIERAISELQqqlarliADTKLRRAKLEMERKASEKQQVRLSENL 862
|
650 660 670 680
....*....|....*....|....*....|....*....|....
gi 33859674 1131 KKLDDTI---------QHVYETLLSIPETMKSCKELQGLLEFLS 1165
Cdd:pfam12128 863 RGLRCEMsklatlkedANSEQAQGSIGERLAQLEDLKLKRDYLS 906
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
648-873 |
1.65e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.30 E-value: 1.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 648 LQERDAAIEEKKQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADL---SAQLQILTSTE-----SQLKEVRSQHSRCVQ 719
Cdd:TIGR02169 229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLeelNKKIKDLGEEEqlrvkEKIGELEAEIASLER 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 720 DLAVK------------------DELLCQLTQSNKEQATQ------WQKEEMELKHIQAELLQQQAVLAKEVQDLRETVE 775
Cdd:TIGR02169 309 SIAEKereledaeerlakleaeiDKLLAEIEELEREIEEErkrrdkLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 776 FIDEESQVAHRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTEAKHEKQALEkTHQHSQELRLLAEQLQSl 855
Cdd:TIGR02169 389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE-IKKQEWKLEQLAADLSK- 466
|
250
....*....|....*...
gi 33859674 856 tlfLQAKLKENKAESEII 873
Cdd:TIGR02169 467 ---YEQELYDLKEEYDRV 481
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
653-840 |
2.71e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.76 E-value: 2.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 653 AAIEEKKQvvkEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQILTSTESQLkEVRSQHSRcvqdLAVKDELLCQLT 732
Cdd:COG4913 610 AKLAALEA---ELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEI-DVASAERE----IAELEAELERLD 681
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 733 QSN------KEQATQWQKEEMELKHIQAELLQQQAVLAKEVQDLRETvefIDEESQVAHRELGQIESQLKVTLELLRERS 806
Cdd:COG4913 682 ASSddlaalEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEE---LDELQDRLEAAEDLARLELRALLEERFAAA 758
|
170 180 190
....*....|....*....|....*....|....*.
gi 33859674 807 LQCETLRDTVDSLRAELASTEAKHEK--QALEKTHQ 840
Cdd:COG4913 759 LGDAVERELRENLEERIDALRARLNRaeEELERAMR 794
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
521-1052 |
2.72e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 48.48 E-value: 2.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 521 LKKLKAKLQSLKTECEEARHSKEMALKGKAAAEAVLEAFRahasQRISQLEQGLTSMQEFRGLLQEAQTQLIGLHTEQKE 600
Cdd:TIGR04523 154 LEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIK----NKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQ 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 601 LAQQTVSLSSALQQdwtsvqlnygiwaallswsreLTKKLTAKSRQALQERDAAIEEKKQV---VKEVEQVSAHLEDCKG 677
Cdd:TIGR04523 230 LKDNIEKKQQEINE---------------------KTTEISNTQTQLNQLKDEQNKIKKQLsekQKELEQNNKKIKELEK 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 678 QIEQLKLE------------NSRLTADLSAQLQILTSTESQLKEVRSQHSRCVQDLAVKDELLCQLTQSNKEQATQWQKE 745
Cdd:TIGR04523 289 QLNQLKSEisdlnnqkeqdwNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEK 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 746 EMELKHIQAE---LLQQQAVLAKEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAE 822
Cdd:TIGR04523 369 QNEIEKLKKEnqsYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQ 448
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 823 LASTEAKHEKqaLEKTHQHsqelrlLAEQLQSLTLflqaKLKENKAESEIILPSTGSAPAQEHPLSNDSSISEQTPTAAV 902
Cdd:TIGR04523 449 DSVKELIIKN--LDNTRES------LETQLKVLSR----SINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLT 516
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 903 DEVpepapvpllGSVKSAFTRVASMASFQPTETPDLEKSLAEMSTVLQElkslcSLLQESKEEatgvLQREICELH---S 979
Cdd:TIGR04523 517 KKI---------SSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKK-----ENLEKEIDE----KNKEIEELKqtqK 578
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 33859674 980 RLQAQEEEHQEALKAKEADMEKLNQALCLLRKNEKEL---LEVIQKQNEKILGQIDKsgqLINLREEVTQLTQSLR 1052
Cdd:TIGR04523 579 SLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLekeLEKAKKENEKLSSIIKN---IKSKKNKLKQEVKQIK 651
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
521-1157 |
3.29e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 48.43 E-value: 3.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 521 LKKLKAKLQSLKTECEEARHSKEMALKGKAAAEAVLEAFRAHASQRISQLEQGLTSMQE----------FRGLLQEAQTQ 590
Cdd:TIGR00618 196 AELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEqlkkqqllkqLRARIEELRAQ 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 591 LIGLHTEQKELAQQTVSLSSALQQDWTSV--QLNYGIWAALLSWSRELTKKLtaKSRQALQERDAAIEEKKQVVKEVEQV 668
Cdd:TIGR00618 276 EAVLEETQERINRARKAAPLAAHIKAVTQieQQAQRIHTELQSKMRSRAKLL--MKRAAHVKQQSSIEEQRRLLQTLHSQ 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 669 SAHLEDCKGQIEQLKLENSRLTAD---LSAQLQILTSTESQLK--------EVRSQHSRCVQDLAVKDeLLCQLTQSNKE 737
Cdd:TIGR00618 354 EIHIRDAHEVATSIREISCQQHTLtqhIHTLQQQKTTLTQKLQslckeldiLQREQATIDTRTSAFRD-LQGQLAHAKKQ 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 738 QATQWQKEEMELKHIQAEL---LQQQAVLAKEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLRERSLQCETLRD 814
Cdd:TIGR00618 433 QELQQRYAELCAAAITCTAqceKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIH 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 815 TVDSLRAELASTEAKHEKQALEKTH-QHSQELRLLAEQLQSLTlflqAKLKENKAESEIILPSTGSAPAQEHPLSNDSSI 893
Cdd:TIGR00618 513 PNPARQDIDNPGPLTRRMQRGEQTYaQLETSEEDVYHQLTSER----KQRASLKEQMQEIQQSFSILTQCDNRSKEDIPN 588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 894 SEQTPTAAVDEVPE--PAPVPLLGSVKSAFTRVASMASFQPTETPDLEKSLAEMSTVLQELKSLCSLLQESKEEATGVLQ 971
Cdd:TIGR00618 589 LQNITVRLQDLTEKlsEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIR 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 972 REICELHSRLQAQEEEHQEALKAKEADMEKLNQALCLLRKNEKELLEvIQKQNEKILGQIDKSGQLINLREEVTQLTQSL 1051
Cdd:TIGR00618 669 VLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEE-YDREFNEIENASSSLGSDLAAREDALNQSLKE 747
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 1052 RRAETETKVLQEALEGQLDPSCQLMATNWIQEKVFLSQEVSKLRVMFLEMKTEKEQLMDKYLSHR-----------HILE 1120
Cdd:TIGR00618 748 LMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIpsdedilnlqcETLV 827
|
650 660 670
....*....|....*....|....*....|....*..
gi 33859674 1121 ENLRRSDTELKKLDDTIQHVYETLLSIPETMKSCKEL 1157
Cdd:TIGR00618 828 QEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQL 864
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
775-1144 |
3.35e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.14 E-value: 3.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 775 EFiDEESQVAHRELGQIESQLKVTLELLRERSLQCETLRDT------VDSLRAELASTEAK---HEKQALEKthQHSQEL 845
Cdd:TIGR02169 167 EF-DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRErekaerYQALLKEKREYEGYellKEKEALER--QKEAIE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 846 RLLAEQLQSLTLfLQAKLKENKAESEIILPSTGSAPAQEHPLSNDSSISEQTPtaavdevpepapvplLGSVKSAFTRVA 925
Cdd:TIGR02169 244 RQLASLEEELEK-LTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEK---------------IGELEAEIASLE 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 926 SMASFQPTETPDLEKSLA----EMSTVLQELKSLCSLLQESKEEATGV------LQREICELHSRLQAQEEEHQEA---L 992
Cdd:TIGR02169 308 RSIAEKERELEDAEERLAkleaEIDKLLAEIEELEREIEEERKRRDKLteeyaeLKEELEDLRAELEEVDKEFAETrdeL 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 993 KAKEADMEKLNQALCLLRKNEKELLEVIQKqnekilgqidKSGQLINLREEVTQLTQSLRRAETETKVLQEAL---EGQL 1069
Cdd:TIGR02169 388 KDYREKLEKLKREINELKRELDRLQEELQR----------LSEELADLNAAIAGIEAKINELEEEKEDKALEIkkqEWKL 457
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 33859674 1070 DPSCQLMATnwIQEKVF-LSQEVSKLRvmflEMKTEKEQLMDKYLSHRHILEENLRRSDTELKKLDDTIQHVYETL 1144
Cdd:TIGR02169 458 EQLAADLSK--YEQELYdLKEEYDRVE----KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTV 527
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
503-869 |
4.39e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 47.91 E-value: 4.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 503 VSQESQRSKTLVSS-CSRVLKKLKAKLQSlkteceearhSKEMALKGKAAAEAVLEAFRahaSQRISQLEQGLTSMQEFR 581
Cdd:pfam12128 373 VTAKYNRRRSKIKEqNNRDIAGIKDKLAK----------IREARDRQLAVAEDDLQALE---SELREQLEAGKLEFNEEE 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 582 GLLQEAQTQLIGLhteqkeLAQQTVSLSSALQQDWTSVQLNygiwaallswsreltkKLTAKSRQALQERDAAIEEKKQV 661
Cdd:pfam12128 440 YRLKSRLGELKLR------LNQATATPELLLQLENFDERIE----------------RAREEQEAANAEVERLQSELRQA 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 662 VKEVEQVSAHLEDCKGQIEQLKlensrlTADLSAQLQILTSTESQLKEVRSQHSRCVQDLA--VKDELLCQ------LTQ 733
Cdd:pfam12128 498 RKRRDQASEALRQASRRLEERQ------SALDELELQLFPQAGTLLHFLRKEAPDWEQSIGkvISPELLHRtdldpeVWD 571
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 734 SNKEQATQWQKEEMELKHIQA--------ELLQQQAVLAKEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLRER 805
Cdd:pfam12128 572 GSVGGELNLYGVKLDLKRIDVpewaaseeELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNA 651
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 33859674 806 SLQCETLRDTVDSLRAELASTEAKHEKQALEKTHQHSQELRLLAEQLQSLTLFLQAKLKENKAE 869
Cdd:pfam12128 652 RLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTE 715
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
521-871 |
5.13e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.45 E-value: 5.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 521 LKKLKAKLQSLKTECEEARHSKEMALKGKAAAEAV--LEAFRAHASQRISQLEQGLTSMQEFRGLLQEAQTQLIGLHTEQ 598
Cdd:COG4717 97 LEELEEELEELEAELEELREELEKLEKLLQLLPLYqeLEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQ 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 599 KELAQQTVSLSSALQQDWTSVQLNYgiwaallswsreltKKLTAKSRQALQERDAAIEEKKQVVKEVEQVSAHLEDckGQ 678
Cdd:COG4717 177 EELEELLEQLSLATEEELQDLAEEL--------------EELQQRLAELEEELEEAQEELEELEEELEQLENELEA--AA 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 679 IEQLKLENSRLTADLSAQLQILTSTESQLKEVRSQHSRcvqdLAVKDELLCQLTQSNKEQATQWQKEEMELKHIQAellq 758
Cdd:COG4717 241 LEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGV----LFLVLGLLALLFLLLAREKASLGKEAEELQALPA---- 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 759 QQAVLAKEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLR--ERSLQCETLRDTVDSLRAELASTEAKhekqALE 836
Cdd:COG4717 313 LEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEelEEELQLEELEQEIAALLAEAGVEDEE----ELR 388
|
330 340 350
....*....|....*....|....*....|....*
gi 33859674 837 KTHQHSQELRLLAEQLQSLTLFLQAKLKENKAESE 871
Cdd:COG4717 389 AALEQAEEYQELKEELEELEEQLEELLGELEELLE 423
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
630-1072 |
5.85e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 47.34 E-value: 5.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 630 LSWSRELTKKLTAKSRQALQERDAA---IEEKKQVVKEVEQVSAHLEDCKGQIEqlklENSRLTADLSAQLQILTSTESQ 706
Cdd:PRK02224 215 LAELDEEIERYEEQREQARETRDEAdevLEEHEERREELETLEAEIEDLRETIA----ETEREREELAEEVRDLRERLEE 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 707 LKEVRsqhsrcvqdlavkDELL--CQLTQSNKEQATQwQKEEMELKHIQA-ELLQQQAVLA----KEVQDLRETVEFIDE 779
Cdd:PRK02224 291 LEEER-------------DDLLaeAGLDDADAEAVEA-RREELEDRDEELrDRLEECRVAAqahnEEAESLREDADDLEE 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 780 ESQVAHRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTEAkhekqALEKTHQHSQELRLLAEQLQSLTLFL 859
Cdd:PRK02224 357 RAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPV-----DLGNAEDFLEELREERDELREREAEL 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 860 QAKLK---ENKAESEIILpSTGSAPAQEHPLsndssisEQTPTAAVDEVPEPAPVPLLGSVKSAFTRVASMASfQPTETP 936
Cdd:PRK02224 432 EATLRtarERVEEAEALL-EAGKCPECGQPV-------EGSPHVETIEEDRERVEELEAELEDLEEEVEEVEE-RLERAE 502
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 937 DLEKSLAEMSTVLQELKSLCSLLQ------ESKEEATGVLQREICELHSRLQAQEEEHQEALKAKEADMEK---LNQALC 1007
Cdd:PRK02224 503 DLVEAEDRIERLEERREDLEELIAerretiEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEvaeLNSKLA 582
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 33859674 1008 LLrKNEKELLEVIQKQNEKILGQIDKSGQLINLREEVTQLTQSLRRAETETKVLQEALEGQLDPS 1072
Cdd:PRK02224 583 EL-KERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEA 646
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
550-775 |
6.49e-05 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 47.25 E-value: 6.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 550 AAAEAvlEAFRAHASQRISQLEQGLTSMQEFRGLLQEAQTQLIGLHTEQKELAQQTVSLSSALQQdwtSVQLNYGIWAAL 629
Cdd:COG3096 904 AAQEA--QAFIQQHGKALAQLEPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQR---RPHFSYEDAVGL 978
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 630 LSWSRELTKKLTAKSRQALQERDAAIEEKKQVVKEVEQVSAHLEDCKGQieqlklensrltadLSAQLQILTSTESQLKE 709
Cdd:COG3096 979 LGENSDLNEKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSS--------------RDAKQQTLQELEQELEE 1044
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 33859674 710 --VRSQHSRCVQDLAVKDELLCQLTQSNKEQA---TQWQKEEMELKHIQAELLQqqavLAKEVQDLRETVE 775
Cdd:COG3096 1045 lgVQADAEAEERARIRRDELHEELSQNRSRRSqleKQLTRCEAEMDSLQKRLRK----AERDYKQEREQVV 1111
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
634-874 |
8.45e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 46.89 E-value: 8.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 634 RELTKKLTAKSRQALQERDAAIEEKKQVVKEVEQVSAHLEDCKGQ-IEQLKLENSRLTADLSAQLQILTSTESQLKEVRS 712
Cdd:pfam02463 172 KEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKeKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 713 QHSRCVQDLAVKDELLCQLTQSNKEQATQWQKEEMELKHIQAELLQQQAVLAKEVQ---DLRETVEFIDEESQVAHRELG 789
Cdd:pfam02463 252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERrkvDDEEKLKESEKEKKKAEKELK 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 790 QIESQLKVTLELLRERSLQCETLRDTVDSLRAELasTEAKHEKQALEKTHQHSQELRLLAEQLQSLTLfLQAKLKENKAE 869
Cdd:pfam02463 332 KEKEEIEELEKELKELEIKREAEEEEEEELEKLQ--EKLEQLEEELLAKKKLESERLSSAAKLKEEEL-ELKSEEEKEAQ 408
|
....*
gi 33859674 870 SEIIL 874
Cdd:pfam02463 409 LLLEL 413
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
678-921 |
9.38e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 9.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 678 QIEQLKLENSRLTADLSAQLQILTSTESQLKEVRSQHSRCVQDLAVKDELLCQLTQSNKEQATQWQKEEMELKHIQAELL 757
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 758 QQQAVLAKEVQDL-----RETVEFI---DEESQVAHRE--LGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTE 827
Cdd:COG4942 101 AQKEELAELLRALyrlgrQPPLALLlspEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 828 AKHEKQALEKTHQHSQELRLLAEQLQSLTLfLQAKLKENKAESEIILPSTGSAPAQEhplsndSSISEQTPTAAVDEVPE 907
Cdd:COG4942 181 AELEEERAALEALKAERQKLLARLEKELAE-LAAELAELQQEAEELEALIARLEAEA------AAAAERTPAAGFAALKG 253
|
250
....*....|....
gi 33859674 908 PAPVPLLGSVKSAF 921
Cdd:COG4942 254 KLPWPVSGRVVRRF 267
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
982-1144 |
9.63e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 9.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 982 QAQEEEHQEALKAKEADMEKLNQALCLLRKNEKELLEVIQKQNEKIlgqIDKSGQLINLREEVTQLTQSLRRAETETKVL 1061
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI---AALARRIRALEQELAALEAELAELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 1062 QEALEGQLDPSCQLMATNWIQE-----KVFLSQEVSKLRVMFLemktekeQLMDKYLSHRHILEENLRRSDTELKKLDDT 1136
Cdd:COG4942 96 RAELEAQKEELAELLRALYRLGrqpplALLLSPEDFLDAVRRL-------QYLKYLAPARREQAEELRADLAELAALRAE 168
|
....*...
gi 33859674 1137 IQHVYETL 1144
Cdd:COG4942 169 LEAERAEL 176
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
656-893 |
1.09e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 46.35 E-value: 1.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 656 EEKKQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAqLQiltsteSQLKEVRSQHSRCVQDLAVKDELLcqltqSN 735
Cdd:pfam10174 268 EDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLA-LQ------TKLETLTNQNSDCKQHIEVLKESL-----TA 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 736 KEQ-ATQWQKEEMEL---------------KHIQaELLQQQAVLAKEVQDLRETVEfideesqVAHRELGQIESQLKVTL 799
Cdd:pfam10174 336 KEQrAAILQTEVDALrlrleekesflnkktKQLQ-DLTEEKSTLAGEIRDLKDMLD-------VKERKINVLQKKIENLQ 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 800 ELLRERSLQCETLRDTVDSLRAELAST--------EAKHEKQALEKT--HQHSQELRLLAEQLQSLTLFLQ-AKLKENKA 868
Cdd:pfam10174 408 EQLRDKDKQLAGLKERVKSLQTDSSNTdtalttleEALSEKERIIERlkEQREREDRERLEELESLKKENKdLKEKVSAL 487
|
250 260
....*....|....*....|....*
gi 33859674 869 ESEIILPSTGSAPAQEHPLSNDSSI 893
Cdd:pfam10174 488 QPELTEKESSLIDLKEHASSLASSG 512
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
634-1164 |
1.42e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.21 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 634 RELTKKLTAKSRQaLQERDAAIEEKKQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQILTSTESQLKEVRsq 713
Cdd:PRK03918 196 KEKEKELEEVLRE-INEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELK-- 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 714 hsrcvqdlavkdellcqltqsnkeqatqwqKEEMELKHIQAELLQQQAVlAKEVQDLRETVEFIDEESQVAHRELGQIES 793
Cdd:PRK03918 273 ------------------------------KEIEELEEKVKELKELKEK-AEEYIKLSEFYEEYLDELREIEKRLSRLEE 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 794 QLKVTLELLRERSLQCETLRDTVDSLRaelastEAKHEKQALEKTHQHSQELRLLAEQLQSLTLFLQAKLKEnKAESEII 873
Cdd:PRK03918 322 EINGIEERIKELEEKEERLEELKKKLK------ELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPE-KLEKELE 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 874 LPSTGSAPAQEHPLSNDSSISE-----QTPTAAVDEVPEPAPV-PLLGSVKSAFTRVASMASFQpTETPDLEKSLAEMST 947
Cdd:PRK03918 395 ELEKAKEEIEEEISKITARIGElkkeiKELKKAIEELKKAKGKcPVCGRELTEEHRKELLEEYT-AELKRIEKELKEIEE 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 948 VLQELKS-LCSLLQESKEEATGVLQREICELHSRLQAQEEEHQ-EALKAKEADMEKLNQALCLLRKNEKELLEVIQKQNE 1025
Cdd:PRK03918 474 KERKLRKeLRELEKVLKKESELIKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 1026 kilgqidksgqlinLREEVTQLTQSLRRAETETKVLQEALEgqldpscqlmatnwiqEKVFLSQEVSKLRVmflemkTEK 1105
Cdd:PRK03918 554 --------------LKKKLAELEKKLDELEEELAELLKELE----------------ELGFESVEELEERL------KEL 597
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 33859674 1106 EQLMDKYLSHRHIlEENLRRSDTELKKLDDTIQhvyETLLSIPETMKSCKELQGLLEFL 1164
Cdd:PRK03918 598 EPFYNEYLELKDA-EKELEREEKELKKLEEELD---KAFEELAETEKRLEELRKELEEL 652
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
703-1066 |
1.70e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.82 E-value: 1.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 703 TESQLKEVRSQHSRcVQDLAVkdELLCQLT--QSNKEQATQWQKEEMELKHIQAELLqqqavlAKEVQDLRETVEFIDEE 780
Cdd:TIGR02168 177 TERKLERTRENLDR-LEDILN--ELERQLKslERQAEKAERYKELKAELRELELALL------VLRLEELREELEELQEE 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 781 SQVAHRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELasTEAKHEKQALEKTHQHSQELRllaEQLQSLTLFLQ 860
Cdd:TIGR02168 248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL--YALANEISRLEQQKQILRERL---ANLERQLEELE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 861 AKLKENKAESEIILPSTGSAPAQEHPLSNDSsiseqtpTAAVDEVPEPApvpllgsvksaftrvasmasfqpTETPDLEK 940
Cdd:TIGR02168 323 AQLEELESKLDELAEELAELEEKLEELKEEL-------ESLEAELEELE-----------------------AELEELES 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 941 SLAEMSTVLQELKSLCSLLQESKEEATGVLQR---EICELHSRLQAQEEEHQEAL-KAKEADMEKLNQALCLLRKNEKEL 1016
Cdd:TIGR02168 373 RLEELEEQLETLRSKVAQLELQIASLNNEIERleaRLERLEDRRERLQQEIEELLkKLEEAELKELQAELEELEEELEEL 452
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 33859674 1017 ---LEVIQKQNEKILGQIDKsgqlinLREEVTQLTQSLRRAETETKVLQEALE 1066
Cdd:TIGR02168 453 qeeLERLEEALEELREELEE------AEQALDAAERELAQLQARLDSLERLQE 499
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
403-855 |
2.02e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 45.73 E-value: 2.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 403 HDLEENLLNSLVLLEVLSHQLQAWKSQLTVPHREARDSSTQTDS-SPCGVTKTPKHLQDSKEIRQALLQArnvmqswgLV 481
Cdd:TIGR00618 375 HTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAfRDLQGQLAHAKKQQELQQRYAELCA--------AA 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 482 SGDLLSLLHLSLTHVQEGRVTVSQESQRSKTLVSSCSRVLKKLKAKLQSLKTECEEARHSKEMALKGKAAAEAVL--EAF 559
Cdd:TIGR00618 447 ITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDnpGPL 526
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 560 RAHASQRISQLEQGLTSMQEFRGLLQEAQTQLIGLhTEQKELAQQTVSlssALQQDWTSVQLNYGIWAALLSWSRELTKK 639
Cdd:TIGR00618 527 TRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASL-KEQMQEIQQSFS---ILTQCDNRSKEDIPNLQNITVRLQDLTEK 602
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 640 LtAKSRQALQERDAAIEEKKQVVKEVEQVSAHLEDCKGQIEQLKL-----------ENSRLTADLSAQLQILTSTESQLK 708
Cdd:TIGR00618 603 L-SEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTalhalqltltqERVREHALSIRVLPKELLASRQLA 681
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 709 EVRSQH-----SRCVQDLAVKDELLCQLTQSNKEQATQWQKEEMELKHIQAELLQQQAVLAKEVQDLRETVEFIDEESQV 783
Cdd:TIGR00618 682 LQKMQSekeqlTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTE 761
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 33859674 784 AHRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTEAKHEKQALEKTHQHSQELRLLAEQLQSL 855
Cdd:TIGR00618 762 AHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQF 833
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
572-823 |
4.10e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.67 E-value: 4.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 572 QGLTSMQEFRGLLQEAQTQLIGLHTEQKELAQQTVSLSSALQQDWTSVQLNYGIWAALLSWSRELTKKLTAKSRQaLQER 651
Cdd:TIGR02169 671 SEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEED-LSSL 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 652 DAAIEEKKQVVKEVEQVSAHLEDckgQIEQLKLENSRLTADLS-AQLQILTSTESQLKEVRSQHSRCVQDLAVK------ 724
Cdd:TIGR02169 750 EQEIENVKSELKELEARIEELEE---DLHKLEEALNDLEARLShSRIPEIQAELSKLEEEVSRIEARLREIEQKlnrltl 826
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 725 -DELLCQLTQSNKEQATQWQ-------KEEMELKHIQAELLQQQAVLAKEVQDLRETVEFIDEESQVAHRELGQIES--- 793
Cdd:TIGR02169 827 eKEYLEKEIQELQEQRIDLKeqiksieKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERkie 906
|
250 260 270
....*....|....*....|....*....|
gi 33859674 794 QLKVTLELLRERSLQCETLRDTVDSLRAEL 823
Cdd:TIGR02169 907 ELEAQIEKKRKRLSELKAKLEALEEELSEI 936
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
753-1066 |
7.81e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.77 E-value: 7.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 753 QAELLQQQAVLAKEVQDLRETVEFIDEESQVAHRElgQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTEAKHEK 832
Cdd:COG1196 201 QLEPLERQAEKAERYRELKEELKELEAELLLLKLR--ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 833 QALEKTHQHSQELRLLAEQLQsltlfLQAKLKENKAESEiilpstgsapaqehplsndssiseqtptaavdevpepapvp 912
Cdd:COG1196 279 LELELEEAQAEEYELLAELAR-----LEQDIARLEERRR----------------------------------------- 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 913 llgsvksaftrvasmasfqptetpDLEKSLAEMSTVLQELKSLCSLLQESKEEAtgvlQREICELHSRLQAQEEEHQEAL 992
Cdd:COG1196 313 ------------------------ELEERLEELEEELAELEEELEELEEELEEL----EEELEEAEEELEEAEAELAEAE 364
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 33859674 993 KAKEADMEKLNQALCLLRKNEKELLEVIQKQNEKILGQIDKSGQLINLREEVTQLTQSLRRAETETKVLQEALE 1066
Cdd:COG1196 365 EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE 438
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
635-892 |
9.93e-04 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 43.41 E-value: 9.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 635 ELTKKLTAKSRQALQERDAAIEEKKQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQILTSTesQLKEVRsQH 714
Cdd:COG5185 218 ESTLLEKAKEIINIEEALKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENANN--LIKQFE-NT 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 715 SRCVQDlAVKDELLCQLTQSNKEQATQWQKE---EMELKHIQAELLQQQAVLAKEVQDLRETVEFIDEEsqvahrelgqI 791
Cdd:COG5185 295 KEKIAE-YTKSIDIKKATESLEEQLAAAEAEqelEESKRETETGIQNLTAEIEQGQESLTENLEAIKEE----------I 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 792 ESqlKVTLELLRERSLQCETLRDTVDSLRAELASTEAKHEKQALEKTHQHSQELRLLAEQLQSLTLFLQAKLKENKAESE 871
Cdd:COG5185 364 EN--IVGEVELSKSSEELDSFKDTIESTKESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQRQIEQATSSNEEVSK 441
|
250 260
....*....|....*....|.
gi 33859674 872 IILPSTGSAPAQEHPLSNDSS 892
Cdd:COG5185 442 LLNELISELNKVMREADEESQ 462
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
638-836 |
1.02e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.89 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 638 KKLTAKSRQALQERDAAIEEKKQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQIL-------------TSTE 704
Cdd:COG3883 26 SELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELgeraralyrsggsVSYL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 705 SQLKEVRSqhsrcVQDLAVKDELLCQLTQSNKEQATQWQKEEMELKHIQAELLQQQAVLAKEVQDLRETVEFIDEESQVA 784
Cdd:COG3883 106 DVLLGSES-----FSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQ 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 33859674 785 HRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTEAKHEKQALE 836
Cdd:COG3883 181 EALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAA 232
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
563-808 |
1.13e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.37 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 563 ASQRISQLEQGLTSMQEfrgLLQEAQTQLIGLHTEQKELAQQTVSLSSALQQDWTSVQLnYGIWAALLSWSRELT----- 637
Cdd:COG4913 608 NRAKLAALEAELAELEE---ELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDV-ASAEREIAELEAELErldas 683
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 638 ----KKLTAKSRQALQERDAAIEEKKQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQilTSTESQLKEVRSQ 713
Cdd:COG4913 684 sddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR--ALLEERFAAALGD 761
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 714 HSRcvqdlavkDELLCQLTQSNKEQATQWQKEEMELKHIQAELLQQQAVLAKEVQ-DLRETVEFIDEESQVAHRELGQIE 792
Cdd:COG4913 762 AVE--------RELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDaDLESLPEYLALLDRLEEDGLPEYE 833
|
250
....*....|....*.
gi 33859674 793 SQLKvtlELLRERSLQ 808
Cdd:COG4913 834 ERFK---ELLNENSIE 846
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
655-1156 |
1.39e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 42.70 E-value: 1.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 655 IEEKKQVVKEVEqvsAHLEDCKGQIEQLKLENSRLTADLSAQLQILTSTESQLKEVRSQHSRCVQDLAVKDELLCQLTQS 734
Cdd:TIGR04523 206 LKKKIQKNKSLE---SQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKK 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 735 NKEQATQWQKEEMELKHIQAellQQQAVLAKEvqdLRETVEFIDEESQVAHRELGQIE---SQLKVTLELLRErslQCET 811
Cdd:TIGR04523 283 IKELEKQLNQLKSEISDLNN---QKEQDWNKE---LKSELKNQEKKLEEIQNQISQNNkiiSQLNEQISQLKK---ELTN 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 812 LRDTVDSLRAELasTEAKHEKQALEKTHQ-HSQELRLLAEQLQSLTLFLQAKLKENKAESEIIlpstgsapaqEHPLSND 890
Cdd:TIGR04523 354 SESENSEKQREL--EEKQNEIEKLKKENQsYKQEIKNLESQINDLESKIQNQEKLNQQKDEQI----------KKLQQEK 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 891 SSISEQtptaavdevpepapvpllgsvksaFTRVASMASFQPTETPDLEKSLAEMSTVLQELKSlcslLQESKEEATGVL 970
Cdd:TIGR04523 422 ELLEKE------------------------IERLKETIIKNNSEIKDLTNQDSVKELIIKNLDN----TRESLETQLKVL 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 971 QREICELHSRLQAQEEEhqeaLKAKEADMEKLNQALCLLRKNEKELleviQKQNEKILGQIDKsgqlinLREEVTQLTQS 1050
Cdd:TIGR04523 474 SRSINKIKQNLEQKQKE----LKSKEKELKKLNEEKKELEEKVKDL----TKKISSLKEKIEK------LESEKKEKESK 539
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 1051 LRRAETETKVLQEALegqldpscqlmaTNWIQEKVFLS--QEVSKLRVMFLEMK---TEKEQLMDKYLSHRHILEENLRR 1125
Cdd:TIGR04523 540 ISDLEDELNKDDFEL------------KKENLEKEIDEknKEIEELKQTQKSLKkkqEEKQELIDQKEKEKKDLIKEIEE 607
|
490 500 510
....*....|....*....|....*....|....
gi 33859674 1126 SDTELKKLDDTIQHV---YETLLSIPETMKSCKE 1156
Cdd:TIGR04523 608 KEKKISSLEKELEKAkkeNEKLSSIIKNIKSKKN 641
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
525-874 |
1.74e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 42.82 E-value: 1.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 525 KAKLQSLKTECEEARHSKEMALKGKAAAEAVLEAFRAHASQRISQL----EQGLTSMQEFRGLLQEAQTQLIGLHTEQKE 600
Cdd:PTZ00121 1443 AKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAkkkaEEAKKKADEAKKAAEAKKKADEAKKAEEAK 1522
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 601 LAQQTVSLSSALQQDwtsvqlnygiwaallswsrELTKklTAKSRQALQERDAAIEEKKQVVKEVEQVSAHLEDCKG--- 677
Cdd:PTZ00121 1523 KADEAKKAEEAKKAD-------------------EAKK--AEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMalr 1581
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 678 ------QIEQLKLENSRLTADLSAQLQILTSTESQLKEVRSQHSRCVQDLAVKDELLCQLTQSNKEQATQWQKEEMELKH 751
Cdd:PTZ00121 1582 kaeeakKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKI 1661
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 752 IQAELLQQQAVLAKEVQDLRETvefiDEESQVAHRELGQIESQLKVTLELLR---ERSLQCETLR--DTVDSLRAELAST 826
Cdd:PTZ00121 1662 KAAEEAKKAEEDKKKAEEAKKA----EEDEKKAAEALKKEAEEAKKAEELKKkeaEEKKKAEELKkaEEENKIKAEEAKK 1737
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 33859674 827 EAKHEKQALEKTHQHSQElrllAEQLQSLTLFLQAKLKENKAESEIIL 874
Cdd:PTZ00121 1738 EAEEDKKKAEEAKKDEEE----KKKIAHLKKEEEKKAEEIRKEKEAVI 1781
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
645-855 |
2.31e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 42.25 E-value: 2.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 645 RQALQERDAAIEEKKQVVKEVEQVSAHLEdcKGQIEQLKLENSRLTADLSAQLQILTSTESQLKEVRsqhsrcvQDLAVK 724
Cdd:COG3096 461 EQKLSVADAARRQFEKAYELVCKIAGEVE--RSQAWQTARELLRRYRSQQALAQRLQQLRAQLAELE-------QRLRQQ 531
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 725 DELLCQLTQSNKEQATQWQKEEmELKHIQAELLQQQAVLAKEVQDLREtvefideesqvAHRELGQIESQLKVTLELLRE 804
Cdd:COG3096 532 QNAERLLEEFCQRIGQQLDAAE-ELEELLAELEAQLEELEEQAAEAVE-----------QRSELRQQLEQLRARIKELAA 599
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 33859674 805 RSLQCETLRDTVDSLR----AELASTEA--KHEKQALEKTHQHSQELRLLAEQLQSL 855
Cdd:COG3096 600 RAPAWLAAQDALERLReqsgEALADSQEvtAAMQQLLEREREATVERDELAARKQAL 656
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
657-857 |
2.52e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 41.75 E-value: 2.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 657 EKKQVVKEVEQVSAHLEDCKGQIEQLKLENsrltadLSAQLQILTSTESQL-----KEVRSQHSrcVQDLavKDELLCQL 731
Cdd:PRK04778 250 DHLDIEKEIQDLKEQIDENLALLEELDLDE------AEEKNEEIQERIDQLydileREVKARKY--VEKN--SDTLPDFL 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 732 TQSnKEQATQWQKEEMELK---HIQAELLQQQAVLAKEVQDLRETVEFIDE---ESQVAHRElgqIESQLKVTLELLRER 805
Cdd:PRK04778 320 EHA-KEQNKELKEEIDRVKqsyTLNESELESVRQLEKQLESLEKQYDEITEriaEQEIAYSE---LQEELEEILKQLEEI 395
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 33859674 806 SLQCETLRDTVDSLRaelasteaKHEKQALEKTHQHSQELRLLAEQLQSLTL 857
Cdd:PRK04778 396 EKEQEKLSEMLQGLR--------KDELEAREKLERYRNKLHEIKRYLEKSNL 439
|
|
| ATG14 |
pfam10186 |
Vacuolar sorting 38 and autophagy-related subunit 14; The Atg14 or Apg14 proteins are ... |
581-781 |
2.54e-03 |
|
Vacuolar sorting 38 and autophagy-related subunit 14; The Atg14 or Apg14 proteins are hydrophilic proteins with a predicted molecular mass of 40.5 kDa, and have a coiled-coil motif at the N terminus region. Yeast cells with mutant Atg14 are defective not only in autophagy but also in sorting of carboxypeptidase Y (CPY), a vacuolar-soluble hydrolase, to the vacuole. Subcellular fractionation indicate that Apg14p and Apg6p are peripherally associated with a membrane structure(s). Apg14p was co-immunoprecipitated with Apg6p, suggesting that they form a stable protein complex. These results imply that Apg6/Vps30p has two distinct functions: in the autophagic process and in the vacuolar protein sorting pathway. Apg14p may be a component specifically required for the function of Apg6/Vps30p through the autophagic pathway. There are 17 auto-phagosomal component proteins which are categorized into six functional units, one of which is the AS-PI3K complex (Vps30/Atg6 and Atg14). The AS-PI3K complex and the Atg2-Atg18 complex are essential for nucleation, and the specific function of the AS-PI3K apparently is to produce phosphatidylinositol 3-phosphate (PtdIns(3)P) at the pre-autophagosomal structure (PAS). The localization of this complex at the PAS is controlled by Atg14. Autophagy mediates the cellular response to nutrient deprivation, protein aggregation, and pathogen invasion in humans, and malfunction of autophagy has been implicated in multiple human diseases including cancer. This effect seems to be mediated through direct interaction of the human Atg14 with Beclin 1 in the human phosphatidylinositol 3-kinase class III complex.
Pssm-ID: 462986 [Multi-domain] Cd Length: 347 Bit Score: 41.67 E-value: 2.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 581 RGLLQEAQTQLIGLHTEQKELAQQtvsLSSALQQDWTSVQLNygiwaallswSRELTKKLTAKSRQALQerdAAIEEKKQ 660
Cdd:pfam10186 18 RNRLYELRVDLARLLSEKDSLKKK---VEEALEGKEEGEQLE----------DNIGNKKLKLRLLKSEV---AISNERLN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 661 VVKE-VEQVSAHLEDCKGQIEQLKLENSRLTADLSaqlqiltSTESQLKEVRSqhsrcvqdlavkdELLCQLTQSNKEQA 739
Cdd:pfam10186 82 EIKDkLDQLRREIAEKKKKIEKLRSSLKQRRSDLE-------SASYQLEERRA-------------SQLAKLQNSIKRIK 141
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 33859674 740 TQWQKEEMELKHIQAELLQQQAVLAkevqDLRETVEFIDEES 781
Cdd:pfam10186 142 QKWTALHSKTAESRSFLCRELAKLY----GLRQVVKSKNGSS 179
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
627-912 |
3.03e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.43 E-value: 3.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 627 AALLSWSRELTKKLTAKSRQALQERDAAIEEKKQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQILTSTESQ 706
Cdd:COG4372 23 GILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 707 LKEVRSQHSRCVQDLavkdellcqltQSNKEQATQWQKEEMELKHIQAELLQQQAVLAKEVQDLRETVEFIDEE-----S 781
Cdd:COG4372 103 LESLQEEAEELQEEL-----------EELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEElaaleQ 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 782 QVAHRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTEAKHEKQALEKTHQHSQELRLLAEQLQSLTLFLQA 861
Cdd:COG4372 172 ELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEEL 251
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 33859674 862 KLKENKAESEIILPSTGSAPAQEHPLSNDSSISEQTPTAAVDEVPEPAPVP 912
Cdd:COG4372 252 LEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLL 302
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
655-1121 |
3.08e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 41.63 E-value: 3.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 655 IEEKKQVVKEVEqvsahlEDCKGQIEQLKLENSR---LTA---DLSAQLQILTSTESQLKEvrsqhsrcvqDLAVKDELL 728
Cdd:pfam05483 263 LEESRDKANQLE------EKTKLQDENLKELIEKkdhLTKeleDIKMSLQRSMSTQKALEE----------DLQIATKTI 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 729 CQLTQSNKEQatqwqkeeMElkhiqaELLQQQAVLAKEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLRERSLQ 808
Cdd:pfam05483 327 CQLTEEKEAQ--------ME------ELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSE 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 809 CETLRDTVDSLRAELasTEAKHEKQALEKTHQHSQELRLLAEQL----QSLTLFLQAKLKENKaESEIILPSTgsapaqe 884
Cdd:pfam05483 393 LEEMTKFKNNKEVEL--EELKKILAEDEKLLDEKKQFEKIAEELkgkeQELIFLLQAREKEIH-DLEIQLTAI------- 462
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 885 hplsndsSISEQTPTAAVDEVPEPAPVPLLGSVKSaftrvasmasfqpteTPDLEKSLAEMSTVLQELKSLCSLLQESKE 964
Cdd:pfam05483 463 -------KTSEEHYLKEVEDLKTELEKEKLKNIEL---------------TAHCDKLLLENKELTQEASDMTLELKKHQE 520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 965 EATGVLQREICELHSRLQAQEEEHQ---EALKAKEADMEKLNQALCLLRKNEKELLEVIQKQNEKILGQIDKSGQLINLR 1041
Cdd:pfam05483 521 DIINCKKQEERMLKQIENLEEKEMNlrdELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLK 600
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 1042 EEVTQLTQSLRRAETETKVLQEALEGQldpSCQLMATNWIQEKVFLSQEVSKLRvmFLEM-KTEKEQLMDKYLSHRHILE 1120
Cdd:pfam05483 601 KQIENKNKNIEELHQENKALKKKGSAE---NKQLNAYEIKVNKLELELASAKQK--FEEIiDNYQKEIEDKKISEEKLLE 675
|
.
gi 33859674 1121 E 1121
Cdd:pfam05483 676 E 676
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
678-999 |
3.73e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.04 E-value: 3.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 678 QIEQLKLENSRLTADLSAQLQILTSTESQLKEVRSQhsrcvqdlavkdellcqlTQSNKEQATQWQKEEMELKHIQAELL 757
Cdd:COG4372 39 ELDKLQEELEQLREELEQAREELEQLEEELEQARSE------------------LEQLEEELEELNEQLQAAQAELAQAQ 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 758 QQQAVLAKEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTEAKHEKQALEK 837
Cdd:COG4372 101 EELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAE 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 838 THQHSQELRLLAEQlQSLTLFLQAKLKENKAESEIILPSTGSAPAQEHPLSNDSSISEQTPTAAVDEVPEPAPVPLLGSV 917
Cdd:COG4372 181 AEQALDELLKEANR-NAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKE 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 918 KSAFTRVASMASFQPTETPDLEKSLAEMSTVLQELKSLCSLLQESKEEATGVLQREICELHSRLQAQEEEHQEALKAKEA 997
Cdd:COG4372 260 IEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAEL 339
|
..
gi 33859674 998 DM 999
Cdd:COG4372 340 AD 341
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
521-760 |
4.35e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 41.44 E-value: 4.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 521 LKKLKAKLQSLKTECEEARHSKEmALKgKAAAEAVLEAFRAHASQRI-SQLEQGLTSMQEFRGLLQEAQTQLIGLHTeQK 599
Cdd:PRK11281 82 TEQLKQQLAQAPAKLRQAQAELE-ALK-DDNDEETRETLSTLSLRQLeSRLAQTLDQLQNAQNDLAEYNSQLVSLQT-QP 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 600 ELAQQTvsLSSALQQdwtSVQLNygiwaALLSWSRELTKKLTAKSRQALQERDAAIEekkqvvkeveqvsahledckGQI 679
Cdd:PRK11281 159 ERAQAA--LYANSQR---LQQIR-----NLLKGGKVGGKALRPSQRVLLQAEQALLN--------------------AQN 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 680 EQLKLE---NSRLTADLSAQLQILTstesqLKEVRSQHSrcVQDLavkDELLCQ--LTQSnKEQATQWQKEEMELKHIQA 754
Cdd:PRK11281 209 DLQRKSlegNTQLQDLLQKQRDYLT-----ARIQRLEHQ--LQLL---QEAINSkrLTLS-EKTVQEAQSQDEAARIQAN 277
|
....*.
gi 33859674 755 ELLQQQ 760
Cdd:PRK11281 278 PLVAQE 283
|
|
| HAP1_N |
pfam04849 |
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found ... |
704-874 |
5.52e-03 |
|
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found in several huntingtin-associated protein 1 (HAP1) homologs. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner. However, its possible role in the pathogenesis of Huntington's disease is unclear. This family also includes a similar N-terminal conserved region from hypothetical protein products of ALS2CR3 genes found in the human juvenile amyotrophic lateral sclerosis critical region 2q33-2q34.
Pssm-ID: 461455 [Multi-domain] Cd Length: 309 Bit Score: 40.39 E-value: 5.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 704 ESQLKEVRSQHSRCVQDLAVKDELLcQLTQSNKEQATQWQKEEMELKH----------IQAELLQQQ-AVLAKEVQDLR- 771
Cdd:pfam04849 107 EEQLGSAREEILQLRHELSKKDDLL-QIYSNDAEESETESSCSTPLRRnesfsslhgcVQLDALQEKlRGLEEENLKLRs 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 772 -------ETVEFIDEESQVAH---RELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTEAKHEKQALEKtHQH 841
Cdd:pfam04849 186 eashlktETDTYEEKEQQLMSdcvEQLSEANQQMAELSEELARKMEENLRQQEEITSLLAQIVDLQHKCKELGIEN-EEL 264
|
170 180 190
....*....|....*....|....*....|...
gi 33859674 842 SQELRLLAEQLQSLTLFLQaKLKENKAESEIIL 874
Cdd:pfam04849 265 QQHLQASKEAQRQLTSELQ-ELQDRYAECLGML 296
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
521-832 |
5.68e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 40.87 E-value: 5.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 521 LKKLKAKLQSLKTECEEARHSKEMALKGKaaaeavleafrAHASQRISQLEQGLTSMQE-FRGLLQEAQTQLIGLHTEQK 599
Cdd:pfam15921 428 VQRLEALLKAMKSECQGQMERQMAAIQGK-----------NESLEKVSSLTAQLESTKEmLRKVVEELTAKKMTLESSER 496
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 600 ELAQQTVSLSSALQqdwtsvqlnygiwaALLSWSRELTKkltaksrqaLQERdaaIEEKKQVVKEVEQVSAHLEDCKGQI 679
Cdd:pfam15921 497 TVSDLTASLQEKER--------------AIEATNAEITK---------LRSR---VDLKLQELQHLKNEGDHLRNVQTEC 550
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 680 EQLKLEnsrlTADLSAQLQILTSTESQLKEVRSQHSRCVQDLAVKDELLCQLTQSNKEQATQWQ----KEEMELKHIQA- 754
Cdd:pfam15921 551 EALKLQ----MAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKilkdKKDAKIRELEAr 626
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 755 ----ELLQQQAVLA-----KEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLRERSLQCETlrdTVDSLRAELAS 825
Cdd:pfam15921 627 vsdlELEKVKLVNAgserlRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMET---TTNKLKMQLKS 703
|
....*..
gi 33859674 826 TEAKHEK 832
Cdd:pfam15921 704 AQSELEQ 710
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
678-832 |
9.01e-03 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 38.37 E-value: 9.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859674 678 QIEQLKLENSRLTADLSAQLQILTSTESQLKEVRSQHSrcvqdlavkdellcqltQSNKEQATQWQKEEMELKHIQAELL 757
Cdd:pfam08614 15 RTALLEAENAKLQSEPESVLPSTSSSKLSKASPQSASI-----------------QSLEQLLAQLREELAELYRSRGELA 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 33859674 758 QQQAVLAKEVQDLRETVEFIDEESQVAHRELGQIESQLKVTLELLRERSLQCETLRDTVDSLRAELASTEAKHEK 832
Cdd:pfam08614 78 QRLVDLNEELQELEKKLREDERRLAALEAERAQLEEKLKDREEELREKRKLNQDLQDELVALQLQLNMAEEKLRK 152
|
|
| |
