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Conserved domains on  [gi|134133288|ref|NP_060227|]
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zinc finger protein 407 isoform 1 [Homo sapiens]

Protein Classification

zf-H2C2_5 and zf-H2C2_2 domain-containing protein( domain architecture ID 10604184)

zf-H2C2_5 and zf-H2C2_2 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1728-1753 2.29e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.05  E-value: 2.29e-04
                           10        20
                   ....*....|....*....|....*.
gi 134133288  1728 HLTRHKRVHTGEKPYRCPWCDYRSNC 1753
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1642-1669 4.88e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 4.88e-04
                           10        20
                   ....*....|....*....|....*...
gi 134133288  1642 ALNNHMKLHTGEKPFKCtwPTCHYSFLT 1669
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKC--PECGKSFKS 26
zf-H2C2_5 pfam13909
C2H2-type zinc-finger domain;
1714-1738 7.17e-04

C2H2-type zinc-finger domain;


:

Pssm-ID: 404746 [Multi-domain]  Cd Length: 25  Bit Score: 38.69  E-value: 7.17e-04
                           10        20
                   ....*....|....*....|....*
gi 134133288  1714 FKCDECNFASTTQSHLTRHKRVHTG 1738
Cdd:pfam13909    1 YKCSQCDYSTAWKSNLKRHLRKHTG 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1557-1578 1.13e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 1.13e-03
                           10        20
                   ....*....|....*....|..
gi 134133288  1557 HIRTHTGSKPFKCKICHFATAQ 1578
Cdd:pfam13465    5 HMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1700-1725 1.97e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 1.97e-03
                           10        20
                   ....*....|....*....|....*.
gi 134133288  1700 ALTKHRRQHTGEKPFKCDECNFASTT 1725
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1728-1753 2.29e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.05  E-value: 2.29e-04
                           10        20
                   ....*....|....*....|....*.
gi 134133288  1728 HLTRHKRVHTGEKPYRCPWCDYRSNC 1753
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1642-1669 4.88e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 4.88e-04
                           10        20
                   ....*....|....*....|....*...
gi 134133288  1642 ALNNHMKLHTGEKPFKCtwPTCHYSFLT 1669
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKC--PECGKSFKS 26
zf-H2C2_5 pfam13909
C2H2-type zinc-finger domain;
1714-1738 7.17e-04

C2H2-type zinc-finger domain;


Pssm-ID: 404746 [Multi-domain]  Cd Length: 25  Bit Score: 38.69  E-value: 7.17e-04
                           10        20
                   ....*....|....*....|....*
gi 134133288  1714 FKCDECNFASTTQSHLTRHKRVHTG 1738
Cdd:pfam13909    1 YKCSQCDYSTAWKSNLKRHLRKHTG 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1557-1578 1.13e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 1.13e-03
                           10        20
                   ....*....|....*....|..
gi 134133288  1557 HIRTHTGSKPFKCKICHFATAQ 1578
Cdd:pfam13465    5 HMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1700-1725 1.97e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 1.97e-03
                           10        20
                   ....*....|....*....|....*.
gi 134133288  1700 ALTKHRRQHTGEKPFKCDECNFASTT 1725
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1712-1767 3.42e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 42.38  E-value: 3.42e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 134133288 1712 KPFKCDECNFASTTQSHLTRHKRVHTGEKPYRCPWC---DYRSNCAENIRKHILHTGKH 1767
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSgcdKSFSRPLELSRHLRTHHNNP 90
 
Name Accession Description Interval E-value
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1728-1753 2.29e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.05  E-value: 2.29e-04
                           10        20
                   ....*....|....*....|....*.
gi 134133288  1728 HLTRHKRVHTGEKPYRCPWCDYRSNC 1753
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1642-1669 4.88e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 4.88e-04
                           10        20
                   ....*....|....*....|....*...
gi 134133288  1642 ALNNHMKLHTGEKPFKCtwPTCHYSFLT 1669
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKC--PECGKSFKS 26
zf-H2C2_5 pfam13909
C2H2-type zinc-finger domain;
1714-1738 7.17e-04

C2H2-type zinc-finger domain;


Pssm-ID: 404746 [Multi-domain]  Cd Length: 25  Bit Score: 38.69  E-value: 7.17e-04
                           10        20
                   ....*....|....*....|....*
gi 134133288  1714 FKCDECNFASTTQSHLTRHKRVHTG 1738
Cdd:pfam13909    1 YKCSQCDYSTAWKSNLKRHLRKHTG 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1557-1578 1.13e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 1.13e-03
                           10        20
                   ....*....|....*....|..
gi 134133288  1557 HIRTHTGSKPFKCKICHFATAQ 1578
Cdd:pfam13465    5 HMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1700-1725 1.97e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 1.97e-03
                           10        20
                   ....*....|....*....|....*.
gi 134133288  1700 ALTKHRRQHTGEKPFKCDECNFASTT 1725
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1712-1767 3.42e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 42.38  E-value: 3.42e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 134133288 1712 KPFKCDECNFASTTQSHLTRHKRVHTGEKPYRCPWC---DYRSNCAENIRKHILHTGKH 1767
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSgcdKSFSRPLELSRHLRTHHNNP 90
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 1695-1764 4.77e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.01  E-value: 4.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 134133288 1695 GGTRHALTKHRRQHT-GEKPFKCD--ECNFASTTQSHLTRHKR-------------------VHTGEKPYRCPWCDYRSN 1752
Cdd:COG5189   330 GGERNIDTPSRMLKVkDGKPYKCPveGCNKKYKNQNGLKYHMLhghqnqklhenpspekmniFSAKDKPYRCEVCDKRYK 409

                          90
                  ....*....|..
gi 134133288 1753 CAENIRKHILHT 1764
Cdd:COG5189   410 NLNGLKYHRKHS 421
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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