hsp90 co-chaperone Cdc37-like 1 [Homo sapiens]
CDC37_N and CDC37_M domain-containing protein( domain architecture ID 10263481)
CDC37_N and CDC37_M domain-containing protein
List of domain hits
Name | Accession | Description | Interval | E-value | |||
CDC37_M | smart01070 | Cdc37 Hsp90 binding domain; Cdc37 is a molecular chaperone required for the activity of ... |
138-282 | 4.50e-60 | |||
Cdc37 Hsp90 binding domain; Cdc37 is a molecular chaperone required for the activity of numerous eukaryotic protein kinases. This domains corresponds to the Hsp90 chaperone (Heat shocked protein 90) binding domain of Cdc37. It is found between the N terminal Cdc37 domain which is predominantly involved in kinase binding, and the C terminal domain of Cdc37 whose function is unclear. : Pssm-ID: 215010 Cd Length: 155 Bit Score: 189.90 E-value: 4.50e-60
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CDC37_N super family | cl03951 | Cdc37 N terminal kinase binding; Cdc37 is a molecular chaperone required for the activity of ... |
71-139 | 4.17e-03 | |||
Cdc37 N terminal kinase binding; Cdc37 is a molecular chaperone required for the activity of numerous eukaryotic protein kinases. This domain corresponds to the N terminal domain which binds predominantly to protein kinases and is found N terminal to the Hsp (Heat shocked protein) 90-binding domain pfam08565. Expression of a construct consisting of only the N-terminal domain of Saccharomyces pombe Cdc37 results in cellular viability. This indicates that interactions with the cochaperone Hsp90 may not be essential for Cdc37 function. The actual alignment was detected with superfamily member smart01071: Pssm-ID: 446243 [Multi-domain] Cd Length: 154 Bit Score: 37.40 E-value: 4.17e-03
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Name | Accession | Description | Interval | E-value | |||
CDC37_M | smart01070 | Cdc37 Hsp90 binding domain; Cdc37 is a molecular chaperone required for the activity of ... |
138-282 | 4.50e-60 | |||
Cdc37 Hsp90 binding domain; Cdc37 is a molecular chaperone required for the activity of numerous eukaryotic protein kinases. This domains corresponds to the Hsp90 chaperone (Heat shocked protein 90) binding domain of Cdc37. It is found between the N terminal Cdc37 domain which is predominantly involved in kinase binding, and the C terminal domain of Cdc37 whose function is unclear. Pssm-ID: 215010 Cd Length: 155 Bit Score: 189.90 E-value: 4.50e-60
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CDC37_M | pfam08565 | Cdc37 Hsp90 binding domain; Cdc37 is a molecular chaperone required for the activity of ... |
169-278 | 2.56e-17 | |||
Cdc37 Hsp90 binding domain; Cdc37 is a molecular chaperone required for the activity of numerous eukaryotic protein kinases. This domains corresponds to the Hsp90 chaperone (Heat shocked protein 90) binding domain of Cdc37. It is found between the N terminal Cdc37 domain pfam03234, which is predominantly involved in kinase binding, and the C terminal domain of Cdc37 pfam08564 whose function is unclear. Pssm-ID: 430078 Cd Length: 113 Bit Score: 76.46 E-value: 2.56e-17
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CDC37_N | smart01071 | Cdc37 N terminal kinase binding; Cdc37 is a molecular chaperone required for the activity of ... |
71-139 | 4.17e-03 | |||
Cdc37 N terminal kinase binding; Cdc37 is a molecular chaperone required for the activity of numerous eukaryotic protein kinases. This domain corresponds to the N terminal domain which binds predominantly to protein kinases.and is found N terminal to the Hsp (Heat shocked protein) 90-binding domain. Expression of a construct consisting of only the N-terminal domain of Saccharomyces pombe Cdc37 results in cellular viability. This indicates that interactions with the cochaperone Hsp90 may not be essential for Cdc37 function. Pssm-ID: 198139 [Multi-domain] Cd Length: 154 Bit Score: 37.40 E-value: 4.17e-03
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Name | Accession | Description | Interval | E-value | |||
CDC37_M | smart01070 | Cdc37 Hsp90 binding domain; Cdc37 is a molecular chaperone required for the activity of ... |
138-282 | 4.50e-60 | |||
Cdc37 Hsp90 binding domain; Cdc37 is a molecular chaperone required for the activity of numerous eukaryotic protein kinases. This domains corresponds to the Hsp90 chaperone (Heat shocked protein 90) binding domain of Cdc37. It is found between the N terminal Cdc37 domain which is predominantly involved in kinase binding, and the C terminal domain of Cdc37 whose function is unclear. Pssm-ID: 215010 Cd Length: 155 Bit Score: 189.90 E-value: 4.50e-60
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CDC37_M | pfam08565 | Cdc37 Hsp90 binding domain; Cdc37 is a molecular chaperone required for the activity of ... |
169-278 | 2.56e-17 | |||
Cdc37 Hsp90 binding domain; Cdc37 is a molecular chaperone required for the activity of numerous eukaryotic protein kinases. This domains corresponds to the Hsp90 chaperone (Heat shocked protein 90) binding domain of Cdc37. It is found between the N terminal Cdc37 domain pfam03234, which is predominantly involved in kinase binding, and the C terminal domain of Cdc37 pfam08564 whose function is unclear. Pssm-ID: 430078 Cd Length: 113 Bit Score: 76.46 E-value: 2.56e-17
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CDC37_N | smart01071 | Cdc37 N terminal kinase binding; Cdc37 is a molecular chaperone required for the activity of ... |
71-139 | 4.17e-03 | |||
Cdc37 N terminal kinase binding; Cdc37 is a molecular chaperone required for the activity of numerous eukaryotic protein kinases. This domain corresponds to the N terminal domain which binds predominantly to protein kinases.and is found N terminal to the Hsp (Heat shocked protein) 90-binding domain. Expression of a construct consisting of only the N-terminal domain of Saccharomyces pombe Cdc37 results in cellular viability. This indicates that interactions with the cochaperone Hsp90 may not be essential for Cdc37 function. Pssm-ID: 198139 [Multi-domain] Cd Length: 154 Bit Score: 37.40 E-value: 4.17e-03
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Blast search parameters | ||||
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