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Conserved domains on  [gi|150378541|ref|NP_060751|]
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enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform 2 [Homo sapiens]

Protein Classification

Clp protease/crotonase-like domain-containing protein( domain architecture ID 581041)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
crotonase-like super family cl23717
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
38-261 4.65e-74

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


The actual alignment was detected with superfamily member PLN02600:

Pssm-ID: 474030 [Multi-domain]  Cd Length: 251  Bit Score: 226.22  E-value: 4.65e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLR-- 115
Cdd:PLN02600   1 PDSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRst 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 116 ----------------------GLMNDIA-------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 166
Cdd:PLN02600  81 fsslealsiptiavvegaalggGLELALScdlricgEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 167 GTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEG 246
Cdd:PLN02600 161 AREAASMGLVNYCVPAGE----AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEG 236
                        250
                 ....*....|....*
gi 150378541 247 MAAFREKRTPKFVGK 261
Cdd:PLN02600 237 LAAFAEKRKPVYTGK 251
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
38-261 4.65e-74

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 226.22  E-value: 4.65e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLR-- 115
Cdd:PLN02600   1 PDSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRst 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 116 ----------------------GLMNDIA-------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 166
Cdd:PLN02600  81 fsslealsiptiavvegaalggGLELALScdlricgEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 167 GTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEG 246
Cdd:PLN02600 161 AREAASMGLVNYCVPAGE----AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEG 236
                        250
                 ....*....|....*
gi 150378541 247 MAAFREKRTPKFVGK 261
Cdd:PLN02600 237 LAAFAEKRKPVYTGK 251
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
41-254 4.18e-53

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 172.27  E-value: 4.18e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGLMN 119
Cdd:COG1024    8 GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKElAAAADPEEARAFARGLQRLFR 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 120 DI-------------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 168
Cdd:COG1024   87 ALrrlpkpviaavngaalggglelalacdlriaAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAE 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 169 EAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 248
Cdd:COG1024  167 EALELGLVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242

                 ....*.
gi 150378541 249 AFREKR 254
Cdd:COG1024  243 AFLEKR 248
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
40-261 3.76e-37

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 131.33  E-value: 3.76e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541   40 QGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKEREQMSEAEVGVF-------VQ 112
Cdd:pfam00378   4 AGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKEMYGEGPAHQALYrenvldlWT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  113 RLR---------------------GLMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 168
Cdd:pfam00378  83 LLYtcpkpviaavngyaigggcelALACDIiiaADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQ 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  169 EAHVLGLVNHAVAQNEEGDaayqRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 248
Cdd:pfam00378 163 EALKWGLVDKVVPEDQLLD----EARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQ 238
                         250
                  ....*....|...
gi 150378541  249 AFREKRTPKFVGK 261
Cdd:pfam00378 239 AFLEKRKPPWEDQ 251
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
39-200 3.34e-36

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 127.29  E-value: 3.34e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEA--EVGVFVQRLRG 116
Cdd:cd06558    6 DGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKELAALSDAgeEARAFIRELQE 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 117 LMNDI-------------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRL 165
Cdd:cd06558   85 LLRALlrlpkpviaavngaalggglelalacdiriaAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 150378541 166 SGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEI 200
Cdd:cd06558  165 SAEEALELGLVDEVV----PDEELLAAALELARRL 195
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
41-217 4.65e-14

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 71.41  E-value: 4.65e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541   41 GITEILMNRPSAR-NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGAD---------LKEREQMSEaEVGVF 110
Cdd:TIGR02441  22 DVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADiqmiaacktAQEVTQLSQ-EGQEM 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  111 VQRLR-----------------GLMNDIA---------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRR 164
Cdd:TIGR02441 101 FERIEksqkpivaaisgsclggGLELALAchyriatkdRKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKK 180
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 150378541  165 LSGTEAHVLGLVNHAVAQNEEG-DAAYQRARALAQEILPQAPIAVRLGKVAIDR 217
Cdd:TIGR02441 181 IRADRAKKMGIVDQLVDPLGPGlKPAEENTIEYLEEVAVKFAQGLANGKLSINR 234
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
38-261 4.65e-74

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 226.22  E-value: 4.65e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLR-- 115
Cdd:PLN02600   1 PDSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRst 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 116 ----------------------GLMNDIA-------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 166
Cdd:PLN02600  81 fsslealsiptiavvegaalggGLELALScdlricgEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 167 GTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEG 246
Cdd:PLN02600 161 AREAASMGLVNYCVPAGE----AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEG 236
                        250
                 ....*....|....*
gi 150378541 247 MAAFREKRTPKFVGK 261
Cdd:PLN02600 237 LAAFAEKRKPVYTGK 251
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
39-261 5.22e-69

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 213.44  E-value: 5.22e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLM 118
Cdd:PRK07657  11 TPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSLIRTTM 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 119 NDI-------------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 167
Cdd:PRK07657  91 EMVeqlpqpviaaingialggglelalacdfriaAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 168 TEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGM 247
Cdd:PRK07657 171 QEAKEIGLVEFVVPAHL----LEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPTKDRLEGL 246
                        250
                 ....*....|....
gi 150378541 248 AAFREKRTPKFVGK 261
Cdd:PRK07657 247 QAFKEKRKPMYKGE 260
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
41-254 4.18e-53

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 172.27  E-value: 4.18e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGLMN 119
Cdd:COG1024    8 GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKElAAAADPEEARAFARGLQRLFR 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 120 DI-------------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 168
Cdd:COG1024   87 ALrrlpkpviaavngaalggglelalacdlriaAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAE 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 169 EAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 248
Cdd:COG1024  167 EALELGLVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242

                 ....*.
gi 150378541 249 AFREKR 254
Cdd:COG1024  243 AFLEKR 248
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
39-261 1.58e-42

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 145.66  E-value: 1.58e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAE---VGVFVQRL- 114
Cdd:PRK05809  11 EGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEgrkFGLLGNKVf 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 115 RGLMN--------------------------DIASS-AVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 167
Cdd:PRK05809  91 RKLENldkpviaaingfalgggcelsmacdiRIASEkAKFGQPEVGLGITPGFGGTQRLARIVGPGKAKELIYTGDMINA 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 168 TEAHVLGLVNHAVAQNEEGDAAYqrarALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGM 247
Cdd:PRK05809 171 EEALRIGLVNKVVEPEKLMEEAK----ALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFGECFSTEDQTEGM 246
                        250
                 ....*....|....
gi 150378541 248 AAFREKRTPKFVGK 261
Cdd:PRK05809 247 TAFVEKREKNFKNK 260
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
40-261 3.76e-37

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 131.33  E-value: 3.76e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541   40 QGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKEREQMSEAEVGVF-------VQ 112
Cdd:pfam00378   4 AGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKEMYGEGPAHQALYrenvldlWT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  113 RLR---------------------GLMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 168
Cdd:pfam00378  83 LLYtcpkpviaavngyaigggcelALACDIiiaADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQ 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  169 EAHVLGLVNHAVAQNEEGDaayqRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 248
Cdd:pfam00378 163 EALKWGLVDKVVPEDQLLD----EARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQ 238
                         250
                  ....*....|...
gi 150378541  249 AFREKRTPKFVGK 261
Cdd:pfam00378 239 AFLEKRKPPWEDQ 251
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
39-261 6.25e-37

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 131.14  E-value: 6.25e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE------REQMSEAEVGVFVQ 112
Cdd:PRK06688  12 EDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLT-GAGRAFSAGGDIKDfpkappKPPDELAPVNRFLR 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 113 RLRG---------------------LMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 168
Cdd:PRK06688  91 AIAAlpkpvvaavngpavgvgvslaLACDLvyaSESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLLLGEPLSAE 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 169 EAHVLGLVNHAVAqNEEGDAAyqrARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 248
Cdd:PRK06688 171 EALRIGLVNRVVP-AAELDAE---ADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGAT 246
                        250
                 ....*....|...
gi 150378541 249 AFREKRTPKFVGK 261
Cdd:PRK06688 247 AFIEKRKPDFTGF 259
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
39-200 3.34e-36

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 127.29  E-value: 3.34e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEA--EVGVFVQRLRG 116
Cdd:cd06558    6 DGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKELAALSDAgeEARAFIRELQE 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 117 LMNDI-------------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRL 165
Cdd:cd06558   85 LLRALlrlpkpviaavngaalggglelalacdiriaAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 150378541 166 SGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEI 200
Cdd:cd06558  165 SAEEALELGLVDEVV----PDEELLAAALELARRL 195
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
35-261 4.40e-36

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 128.73  E-value: 4.40e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  35 LAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE------------REQM 102
Cdd:PRK09674   5 LVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVIT-GNARFFAAGADLNEmaekdlaatlndPRPQ 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 103 SEAEVGVFVQRLRGLMNDIA-----------------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRL 165
Cdd:PRK09674  84 LWQRLQAFNKPLIAAVNGYAlgagcelallcdiviagENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTGESI 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 166 SGTEAHVLGLVNHaVAQNEegdAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLE 245
Cdd:PRK09674 164 TAQQAQQAGLVSE-VFPPE---LTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTLLAATEDRHE 239
                        250
                 ....*....|....*.
gi 150378541 246 GMAAFREKRTPKFVGK 261
Cdd:PRK09674 240 GISAFLEKRTPDFKGR 255
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
39-261 3.99e-34

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 123.59  E-value: 3.99e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQ-MSEAEVGVFVQRLRGL 117
Cdd:PRK07658   9 EDHVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIH-GEGRFFSAGADIKEFTSvTEAEQATELAQLGQVT 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 118 MNDI-------------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 166
Cdd:PRK07658  87 FERVekfskpviaaihgaalggglelamschirfaTESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLTSEPIT 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 167 GTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEG 246
Cdd:PRK07658 167 GAEALKWGLVNGVFPEET----LLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTSEDAKEG 242
                        250
                 ....*....|....*
gi 150378541 247 MAAFREKRTPKFVGK 261
Cdd:PRK07658 243 VQAFLEKRKPSFSGK 257
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
38-261 5.74e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 120.93  E-value: 5.74e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEreqMSEAE-VGVFVQRLRG 116
Cdd:PRK08138  14 PADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVL-TGGEKVFAAGADIKE---FATAGaIEMYLRHTER 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 117 LMNDIAS-------------------------------SAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRL 165
Cdd:PRK08138  90 YWEAIAQcpkpviaavngyalgggcelamhadiivageSASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMRMALTGCMV 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 166 SGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLE 245
Cdd:PRK08138 170 PAPEALAIGLVSEVV----EDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALERKAFQLLFDSEDQKE 245
                        250
                 ....*....|....*.
gi 150378541 246 GMAAFREKRTPKFVGK 261
Cdd:PRK08138 246 GMDAFLEKRKPAYKGK 261
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
45-258 9.64e-31

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 114.75  E-value: 9.64e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEV--GVF------VQRLR- 115
Cdd:PRK05862  17 ITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVI-TGSEKAFAAGADIKEMADLSFMDVykGDYitnwekVARIRk 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 116 -----------------GLMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 175
Cdd:PRK05862  96 pviaavagyalgggcelAMMCDIiiaADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMDAAEAERAGL 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 176 VNHAVAQNEEGDAAYQRARALAQEILPqapiAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 255
Cdd:PRK05862 176 VSRVVPADKLLDEALAAATTIASFSLP----AVMMAKEAVNRAYETTLAEGLLFERRLFHSLFATEDQKEGMAAFVEKRK 251

                 ...
gi 150378541 256 PKF 258
Cdd:PRK05862 252 PVF 254
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
39-261 9.72e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 112.06  E-value: 9.72e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGV--------- 109
Cdd:PRK06494  11 KGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLKEQAAGGKRGWPEsgfggltsr 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 110 ------FVQRLRG----------LMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEA 170
Cdd:PRK06494  91 fdldkpIIAAVNGvamgggfelaLACDLivaAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMILTGRRVTAREG 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 171 HVLGLVNHAVAQnEEGDAAyqrARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQN--IPTRDRLEGMA 248
Cdd:PRK06494 171 LELGFVNEVVPA-GELLAA---AERWADDILACSPLSIRASKQAVYRGLEVSLEEAITAQRDYPAVEarRASQDYIEGPK 246
                        250
                 ....*....|...
gi 150378541 249 AFREKRTPKFVGK 261
Cdd:PRK06494 247 AFAEKRPPRWKGR 259
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
41-261 1.28e-26

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 103.92  E-value: 1.28e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK-----EREQMSEAEVGVFVQR-- 113
Cdd:PRK08252  12 RVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGIL-TGAGGTFCAGMDLKafargERPSIPGRGFGGLTERpp 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 114 ------------LRG-----LMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVL 173
Cdd:PRK08252  91 rkpliaavegyaLAGgfelaLACDLivaARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMELALTGDMLTAERAHEL 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 174 GLVNHAVAQNEEGDAayqrARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREK 253
Cdd:PRK08252 171 GLVNRLTEPGQALDA----ALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAPVFTSADAKEGATAFAEK 246

                 ....*...
gi 150378541 254 RTPKFVGK 261
Cdd:PRK08252 247 RAPVWTGK 254
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
41-252 1.24e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 101.20  E-value: 1.24e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE--------REQMSEAEVGVFVQ 112
Cdd:PRK06190  13 RVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVL-TGADPAFCAGLDLKElggdgsayGAQDALPNPSPAWP 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 113 RLRG-LMNDIASSAVMG----------LIETTR----------GLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAH 171
Cdd:PRK06190  92 AMRKpVIGAINGAAVTGglelalacdiLIASERarfadtharvGILPGWGLSVRLPQKVGIGRARRMSLTGDFLDAADAL 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 172 VLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEgMCYAQNIPTRDRLEGMAAFR 251
Cdd:PRK06190 172 RAGLVTEVVPHDE----LLPRARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALE-AEAARAHNRSVSPDGIAARR 246

                 .
gi 150378541 252 E 252
Cdd:PRK06190 247 E 247
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
39-259 7.71e-25

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 99.18  E-value: 7.71e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVR-VLLfrSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGL 117
Cdd:PRK07509  10 EDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRaVIL--SGEGGAFCAGLDVKSVASSPGNAVKLLFKRLPGN 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 118 MN-----------------------------------DI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELI 159
Cdd:PRK07509  88 ANlaqrvslgwrrlpvpviaalegvcfggglqialgaDIriaAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKDVARELT 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 160 FTGRRLSGTEAHVLGLVNHAVaqneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIP 239
Cdd:PRK07509 168 YTARVFSAEEALELGLVTHVS------DDPLAAALALAREIAQRSPDAIAAAKRLINRSWTASVRALLARESVEQIRLLL 241
                        250       260
                 ....*....|....*....|
gi 150378541 240 TRDRLEGMAAFREKRTPKFV 259
Cdd:PRK07509 242 GKNQKIAVKAQMKKRAPKFL 261
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
41-258 1.14e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 98.68  E-value: 1.14e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKE------------------REQM 102
Cdd:PRK05980  12 GIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEfsasvaagadvalrdfvrRGQA 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 103 SEAEVGVFVQRLRGLMNDIA-------SSAVMGLIETTR----------GLLPGAGGTQRLPRCLGVALAKELIFTGRRL 165
Cdd:PRK05980  92 MTARLEAFPKPVIAAVNGLAfgggceiTEAVHLAIASERalfakpeirlGMPPTFGGTQRLPRLAGRKRALELLLTGDAF 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 166 SGTEAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLE 245
Cdd:PRK05980 172 SAERALEIGLVNAVVPH----EELLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIESEQFARMAGSADLRE 247
                        250
                 ....*....|...
gi 150378541 246 GMAAFREKRTPKF 258
Cdd:PRK05980 248 GLAAWIERRRPAY 260
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
39-261 2.44e-24

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 97.84  E-value: 2.44e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKERE--QMSEAEVGV--F--VQ 112
Cdd:PRK03580  10 NGSILEITLDRPKA-NAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLKAAAegEAPDADFGPggFagLT 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 113 RLRGL-------MNDI-----------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 168
Cdd:PRK03580  89 EIFDLdkpviaaVNGYafgggfelalaadfivcADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMDAE 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 169 EAHVLGLVNHAVAQNEEGDaayqRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIP----TRDRL 244
Cdd:PRK03580 169 EALRWGIVNRVVPQAELMD----RARELAQQLVNSAPLAIAALKEIYRETSEMPVEEAYRYIRSGVLKHYPsvlhSEDAL 244
                        250
                 ....*....|....*..
gi 150378541 245 EGMAAFREKRTPKFVGK 261
Cdd:PRK03580 245 EGPRAFAEKRDPVWKGR 261
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
28-261 2.93e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 97.85  E-value: 2.93e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  28 SEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEV 107
Cdd:PRK06127   7 SSPTGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESRSDAE 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 108 GVF--------------------VQRLRG----------LMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVAL 154
Cdd:PRK06127  87 AVAayeqaveaaqaaladyakptIACIRGycigggmgiaLACDIriaAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSA 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 155 AKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAIDR----GTEVDIASGMAIE 230
Cdd:PRK06127 167 AKDLFYTARRFDAAEALRIGLVHRVTAADDLETALADYAATIAG----NAPLTLRAAKRAIAEllkdEPERDMAACQALV 242
                        250       260       270
                 ....*....|....*....|....*....|.
gi 150378541 231 GMCYAqnipTRDRLEGMAAFREKRTPKFVGK 261
Cdd:PRK06127 243 AACFD----SEDYREGRAAFMEKRKPVFKGR 269
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
45-256 1.80e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 95.37  E-value: 1.80e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  45 ILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKE---------REqMSEAEVGVF--VQR 113
Cdd:PRK09076  16 LTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNLfadgdkavaRE-MARRFGEAFeaLSA 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 114 LRG------------------LMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 172
Cdd:PRK09076  94 FRGvsiaaingyamggglecaLACDIriaEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVDAATALR 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 173 LGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFRE 252
Cdd:PRK09076 174 IGLVEEVVEKGE----AREAALALAQKVANQSPSAVAACKTLIQAARNGPRAAALALERELFVDLFDTEDQREGVNAFLE 249

                 ....
gi 150378541 253 KRTP 256
Cdd:PRK09076 250 KRAP 253
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
47-260 2.66e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 95.06  E-value: 2.66e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  47 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK---EREQMSEAEVGVFVQRLRGLMNDI-- 121
Cdd:PRK07511  18 LSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVL-TGAGGFFCAGGNLNrllENRAKPPSVQAASIDGLHDWIRAIra 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 122 -----------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 172
Cdd:PRK07511  97 fpkpviaavegaaagagfslalacdllvaARDAKFVMAYVKVGLTPDGGGSWFLARALPRQLATELLLEGKPISAERLHA 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 173 LGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFRE 252
Cdd:PRK07511 177 LGVVNRLAEPGQALAEALALADQLAA----GSPNALARIKSLIADAPEATLAAQLEAERDHFVASLHHADALEGIAAFLE 252

                 ....*...
gi 150378541 253 KRTPKFVG 260
Cdd:PRK07511 253 KRAPDYKR 260
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
47-261 3.56e-23

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 94.78  E-value: 3.56e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  47 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEV----GVFVQRLRGLM---- 118
Cdd:PRK07799  20 MNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCIL-TGAGGAFCAGMDLKAATKKPPGDSfkdgSYDPSRIDALLkgrr 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 119 -----------------------NDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 172
Cdd:PRK07799  99 ltkpliaavegpaiaggteilqgTDIrvaGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEAKE 178
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 173 LGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFRE 252
Cdd:PRK07799 179 IGLIGHVVPD----GQALDKALELAELINANGPLAVQAILRTIRETEGMHENEAFKIDTKIGIPVFLSEDAKEGPRAFAE 254

                 ....*....
gi 150378541 253 KRTPKFVGK 261
Cdd:PRK07799 255 KRAPNFQGR 263
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
39-261 7.15e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 93.90  E-value: 7.15e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRlrglm 118
Cdd:PRK06144  15 RGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAFSTAEDAVAYER----- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 119 ndiASSAVMGLIETTR--------GLLPGAG-----------GT----------------------QRLPRCLGVALAKE 157
Cdd:PRK06144  90 ---RIDRVLGALEQLRvptiaaiaGACVGGGaaiaaacdlriATpsarfgfpiartlgnclsmsnlARLVALLGAARVKD 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 158 LIFTGRRLSGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAqn 237
Cdd:PRK06144 167 MLFTARLLEAEEALAAGLVNEVV----EDAALDARADALAELLAAHAPLTLRATKEALRRLRREGLPDGDDLIRMCYM-- 240
                        250       260
                 ....*....|....*....|....
gi 150378541 238 ipTRDRLEGMAAFREKRTPKFVGK 261
Cdd:PRK06144 241 --SEDFREGVEAFLEKRPPKWKGR 262
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
39-261 2.69e-22

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 92.45  E-value: 2.69e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEvGVFVQRLR--- 115
Cdd:PRK06495  11 SDHVAVVTLDNPPV-NALSRELRDELIAVFDEISERPDVRVVVL-TGAGKVFCAGADLKGRPDVIKGP-GDLRAHNRrtr 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 116 --------------------------GLM--NDI---ASSAVMGLIETTRGLlpgAGGTQRLPRCLGVALAKELIFTGRR 164
Cdd:PRK06495  88 ecfhairecakpviaavngpalgaglGLVasCDIivaSENAVFGLPEIDVGL---AGGGKHAMRLFGHSLTRRMMLTGYR 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 165 LSGTEAHVLGLVNHAVAqneeGDAAYQRARALAQEILPQAPIAVRLGKVAIdrgtevDIASGMAI-EGMCYAQNIP---- 239
Cdd:PRK06495 165 VPAAELYRRGVIEACLP----PEELMPEAMEIAREIASKSPLATRLAKDAL------NTIENMSLrDGYRYEQDITakla 234
                        250       260
                 ....*....|....*....|...
gi 150378541 240 -TRDRLEGMAAFREKRTPKFVGK 261
Cdd:PRK06495 235 kTEDAKEAQRAFLEKRPPVFKGR 257
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
47-261 8.24e-22

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 91.19  E-value: 8.24e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  47 MNRPSARNAL-GNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK---EREQMSEAEVGVFVQRLR------- 115
Cdd:PRK09245  18 MNRPETRNALsDNDAVDALVAACAAINADRSVRAVIL-TGAGTAFSSGGNVKdmrARVGAFGGSPADIRQGYRhgiqrip 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 116 -------------------------GLMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 167
Cdd:PRK09245  97 lalynlevpviaavngpaigagcdlACMCDIriaSETARFAESFVKLGLIPGDGGAWLLPRIIGMARAAEMAFTGDAIDA 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 168 TEAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGM 247
Cdd:PRK09245 177 ATALEWGLVSRVVPA----DQLLPAARALAERIAANPPHALRLTKRLLREGQHASLDTLLELSAAYQALAHHTADHREAV 252
                        250
                 ....*....|....
gi 150378541 248 AAFREKRTPKFVGK 261
Cdd:PRK09245 253 DAFLEKRPPVFTGR 266
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
38-258 1.79e-21

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 90.73  E-value: 1.79e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE----REQMSEAEVGVFVQR 113
Cdd:PLN02664  14 PNSSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIIL-SGAGDHFCSGIDLKTlnsiSEQSSSGDRGRSGER 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 114 LR-----------------------------GLMNDIASS---------AVMGLIETTRGLLPGAGGTQRLPRCLGVALA 155
Cdd:PLN02664  93 LRrkikflqdaitaieqcrkpviaaihgaciGGGVDIVTAcdirycsedAFFSVKEVDLAITADLGTLQRLPSIVGYGNA 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 156 KELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDaayQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYA 235
Cdd:PLN02664 173 MELALTGRRFSGSEAKELGLVSRVFGSKEDLD---EGVRLIAEGIAAKSPLAVTGTKAVLLRSRELSVEQGLDYVATWNS 249
                        250       260
                 ....*....|....*....|...
gi 150378541 236 QNIPTRDRLEGMAAFREKRTPKF 258
Cdd:PLN02664 250 AMLVSDDLNEAVSAQIQKRKPVF 272
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
39-260 3.98e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 89.65  E-value: 3.98e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADL-----------KEREQMSEAEV 107
Cdd:PRK06142  13 ADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKH-FSYGIDLpamagvfgqlgKDGLARPRTDL 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 108 GVFVQRLRGLMNDIAS------SAVMG--------LI-----------------ETTRGLLPGAGGTQRLPRCLGVALAK 156
Cdd:PRK06142  92 RREILRLQAAINAVADcrkpviAAVQGwcigggvdLIsacdmryasadakfsvrEVDLGMVADVGSLQRLPRIIGDGHLR 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 157 ELIFTGRRLSGTEAHVLGLVNHAVaqnEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQ 236
Cdd:PRK06142 172 ELALTGRDIDAAEAEKIGLVNRVY---DDADALLAAAHATAREIAAKSPLAVRGTKEVLDYMRDHRVADGLRYVATWNAA 248
                        250       260
                 ....*....|....*....|....
gi 150378541 237 NIPTRDRLEGMAAFREKRTPKFVG 260
Cdd:PRK06142 249 MLPSKDLTEAIAAHMEKRPPEFTG 272
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
39-256 1.61e-20

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 87.69  E-value: 1.61e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKgVFCAGADLKEreqMSEAEVGVFVQRLRGLM 118
Cdd:PRK08139  18 RDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGK-AFCAGHDLKE---MRAARGLAYFRALFARC 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 119 ND------------------IASSAVMGLI---------ETTR--------GLL---PGAGgtqrLPRCLGVALAKELIF 160
Cdd:PRK08139  94 SRvmqaivalpqpviarvhgIATAAGCQLVascdlavaaDTARfavpgvniGLFcstPMVA----LSRNVPRKQAMEMLL 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 161 TGRRLSGTEAHVLGLVNHAVAQNEEGDAAyqraRALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPT 240
Cdd:PRK08139 170 TGEFIDAATAREWGLVNRVVPADALDAAV----ARLAAVIAAKSPAAVRIGKEAFYRQAEMPLADAYAYAGDVMAENMMA 245
                        250
                 ....*....|....*.
gi 150378541 241 RDRLEGMAAFREKRTP 256
Cdd:PRK08139 246 EDAEEGIDAFLEKRPP 261
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
39-261 1.94e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 87.84  E-value: 1.94e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSEAEV----------- 107
Cdd:PRK06210  13 DSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRG-FCAGADMGELQTIDPSDGrrdtdvrpfvg 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 108 ---------GVFVQRLR------------------GLMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKE 157
Cdd:PRK06210  92 nrrpdyqtrYHFLTALRkpviaaingacagiglthALMCDVrfaADGAKFTTAFARRGLIAEHGISWILPRLVGHANALD 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 158 LIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPqAPIAVRLGKVAIDRGTEVDIASGMAIEGMcyAQN 237
Cdd:PRK06210 172 LLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARNVSP-ASMAVIKRQLYEDAFQTLAEATARANREM--HES 248
                        250       260
                 ....*....|....*....|....
gi 150378541 238 IPTRDRLEGMAAFREKRTPKFVGK 261
Cdd:PRK06210 249 LQRPDFIEGVASFLEKRPPRFPGL 272
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
39-195 8.32e-20

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 88.41  E-value: 8.32e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSAR-NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLK---------EREQMSEAEVG 108
Cdd:PRK11154  13 EDNIAVITIDVPGEKmNTLKAEFAEQVRAILKQLREDKELKGVVFISGKPDNFIAGADINmlaacktaqEAEALARQGQQ 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 109 VF--VQRLR--------------GLMNDIA---------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGR 163
Cdd:PRK11154  93 LFaeIEALPipvvaaihgaclggGLELALAchyrvctddPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTGK 172
                        170       180       190
                 ....*....|....*....|....*....|..
gi 150378541 164 RLSGTEAHVLGLVNHAVAQNEEGDAAYQRARA 195
Cdd:PRK11154 173 QLRAKQALKLGLVDDVVPHSILLEVAVELAKK 204
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
42-261 1.30e-19

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 85.08  E-value: 1.30e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  42 ITEILMNRPSARNALGNVFVSELLETLAQLREDRqVRVLLFRSGVKG-VFCAGADLKEREQMSEAEVGvFVQRLRGLMND 120
Cdd:PRK11423  14 IATITFNNPAKRNALSKVLIDDLMQALSDLNRPE-IRVVILRAPSGSkVWSAGHDIHELPSGGRDPLS-YDDPLRQILRM 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 121 IAS--SAVMGLIE---------------------TTR--------GLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTE 169
Cdd:PRK11423  92 IQKfpKPVIAMVEgsvwggafelimscdliiaasTSTfamtpanlGVPYNLSGILNFTNDAGFHIVKEMFFTASPITAQR 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 170 AHVLGLVNHaVAQNEEGDAAyqrARALAQEILPQAPIAVRLGKvaidrgTEVDI---ASGMAIEGMCYAQNI-----PTR 241
Cdd:PRK11423 172 ALAVGILNH-VVEVEELEDF---TLQMAHHISEKAPLAIAVIK------EQLRVlgeAHPMNPDEFERIQGLrravyDSE 241
                        250       260
                 ....*....|....*....|
gi 150378541 242 DRLEGMAAFREKRTPKFVGK 261
Cdd:PRK11423 242 DYQEGMNAFLEKRKPVFVGH 261
PLN02888 PLN02888
enoyl-CoA hydratase
41-257 8.01e-19

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 83.26  E-value: 8.01e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEVG-------VFVQR 113
Cdd:PLN02888  19 GIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIIL-TGSGRAFCSGVDLTAAEEVFKGDVKdvetdpvAQMER 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 114 LR----GLMNDIASSAVMGL---------------IETTR--GLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 172
Cdd:PLN02888  98 CRkpiiGAINGFAITAGFEIalacdilvasrgakfIDTHAkfGIFPSWGLSQKLSRIIGANRAREVSLTAMPLTAETAER 177
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 173 LGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIE---GMCYAQNIpTRDRLEGMAA 249
Cdd:PLN02888 178 WGLVNHVVEESE----LLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLEkerAHDYYNGM-TKEQFQKMQE 252

                 ....*...
gi 150378541 250 FREKRTPK 257
Cdd:PLN02888 253 FIAGRSSK 260
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
39-261 9.71e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 82.67  E-value: 9.71e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQM---SEAEVGVFVQRLR 115
Cdd:PRK05995  11 RGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVL-AGAGKAFCAGADLNWMKKMagySDDENRADARRLA 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 116 GL----------------------------MNDIA---SSAVMGLIETTRGLLPgaggTQRLP---RCLGVALAKELIFT 161
Cdd:PRK05995  90 DMlraiyrcpkpviarvhgdayaggmglvaACDIAvaaDHAVFCLSEVRLGLIP----ATISPyviRAMGERAARRYFLT 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 162 GRRLSGTEAHVLGLVNHAVAQnEEGDAAYQrarALAQEILPQAPIAVRLGKVAIDrgtevDIAsGMAIEGMCYAQnipTR 241
Cdd:PRK05995 166 AERFDAAEALRLGLVHEVVPA-EALDAKVD---ELLAALVANSPQAVRAGKRLVR-----DVA-GRPIDAALIAD---TA 232
                        250       260       270
                 ....*....|....*....|....*....|
gi 150378541 242 DRL----------EGMAAFREKRTPKFVGK 261
Cdd:PRK05995 233 SRIalirateearEGVAAFLEKRKPAWRGR 262
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
39-257 1.27e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 82.37  E-value: 1.27e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLlfrSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLM 118
Cdd:PRK08150   9 DGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEGVRAVVL---HGEGDHFCAGLDLSELRERDAGEGMHHSRRWHRVF 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 119 NDIA-------------------------------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 167
Cdd:PRK08150  86 DKIQygrvpviaalhgavvggglelasaahirvadESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGRVYDA 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 168 TEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMC--YAQNIP-TRDRL 244
Cdd:PRK08150 166 QEGERLGLAQYLVPAGE----ALDKAMELARRIAQNAPLTNFAVLNALPRIADMSADDGLFVESLMaaVAQSAPeAKERL 241
                        250
                 ....*....|...
gi 150378541 245 egmAAFREKRTPK 257
Cdd:PRK08150 242 ---RAFLEKKAAK 251
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
39-257 1.77e-17

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 79.67  E-value: 1.77e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE--REQMSEAEVGV------- 109
Cdd:PRK09120  15 EDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLT-GAGDAWSAGMDLKEyfRETDAQPEILQerirrea 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 110 --FVQRLR-------GLMN--------------DIA---SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGR 163
Cdd:PRK09120  94 ygWWRRLRwyqkptiAMVNgwcfgggfsplvacDLAiaaDEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALYYIMTGE 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 164 RLSGTEAHVLGLVNHAV--AQNEEgdaayqRARALAQEILPQAPIAVRLGKVAIDRGTEvdiasgmaiegMCYAQNI--- 238
Cdd:PRK09120 174 TFTGRKAAEMGLVNESVplAQLRA------RTRELAAKLLEKNPVVLRAAKDGFKRVRE-----------LTWDQAEdyl 236
                        250       260       270
                 ....*....|....*....|....*....|
gi 150378541 239 -----------PTRDRLEGMAAFREKRTPK 257
Cdd:PRK09120 237 yakleqansldPEGGREEGLKQFLDDKSYK 266
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
45-261 6.06e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 77.69  E-value: 6.06e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRV-LLFRSGvkGVFCAGADLKE--------REQMSEAEVGVF--VQR 113
Cdd:PRK06563  12 IGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVaVLFAHG--EHFTAGLDLADvapklaagGFPFPEGGIDPWgtVGR 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 114 LRG-------------------LMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAH 171
Cdd:PRK06563  90 RLSkplvvavqgycltlgielmLAADIvvaADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLLTGDEFDAQEAL 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 172 VLGLVNHAVAQNEEgdaaYQRARALAQEILPQAPIAVRL----GKVAIDRGTEVDIASGMAIegmcYAQNIPTRDRLEGM 247
Cdd:PRK06563 170 RLGLVQEVVPPGEQ----LERAIELAERIARAAPLGVQAtlasARAAVREGEAAAAAQLPPE----LRPLFTSEDAKEGV 241
                        250
                 ....*....|....
gi 150378541 248 AAFREKRTPKFVGK 261
Cdd:PRK06563 242 QAFLERRPARFKGR 255
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
39-261 7.06e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 78.12  E-value: 7.06e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADL-------------KEREQMSEA 105
Cdd:PRK08260  11 ADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIV-TGAGRAFCAGADLsaggntfdldaprTPVEADEED 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 106 EVGVFVQRLRG--------------------------------LMNDI--AS-SAVMGLIETTRGLLPGAGGTQRLPRCL 150
Cdd:PRK08260  90 RADPSDDGVRDgggrvtlrifdslkpviaavngpavgvgatmtLAMDIrlAStAARFGFVFGRRGIVPEAASSWFLPRLV 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 151 GVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEilpQAPIAVRLGKVAIDRGTEVDI-ASGMAI 229
Cdd:PRK08260 170 GLQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADN---TSPVSVALTRQMMWRMAGADHpMEAHRV 246
                        250       260       270
                 ....*....|....*....|....*....|..
gi 150378541 230 EGMCYAQNIPTRDRLEGMAAFREKRTPKFVGK 261
Cdd:PRK08260 247 DSRAIYSRGRSGDGKEGVSSFLEKRPAVFPGK 278
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
39-261 1.25e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 76.88  E-value: 1.25e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRSGVKGvFCAGADLKERE-----------QMSEAEV 107
Cdd:PRK08140  11 EAGVATLTLNRPDKLNSFTREMHRELREALDQV-EDDGARALLLTGAGRG-FCAGQDLADRDvtpggampdlgESIETFY 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 108 GVFVQRLRGL-------MNDIASSA------VMGLIETTR-----------GLLPGAGGTQRLPRCLGVALAKELIFTGR 163
Cdd:PRK08140  89 NPLVRRLRALplpviaaVNGVAAGAganlalACDIVLAARsasfiqafvkiGLVPDSGGTWFLPRLVGMARALGLALLGE 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 164 RLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDR 243
Cdd:PRK08140 169 KLSAEQAEQWGLIWRVVDDAALADEAQQLAAHLAT----QPTRGLALIKQAMNASATNTLDAQLDLERDLQREAGRSADY 244
                        250
                 ....*....|....*...
gi 150378541 244 LEGMAAFREKRTPKFVGK 261
Cdd:PRK08140 245 AEGVSAFLEKRAPRFTGR 262
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
39-261 4.21e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 75.45  E-value: 4.21e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRSGVKGvFCAGADLKEreQMSEAEVGVFvQRLRGLM 118
Cdd:PRK07659  13 EGRVATIMLNRPEALNALDEPMLKELLQALKEV-AESSAHIVVLRGNGRG-FSAGGDIKM--MLSSNDESKF-DGVMNTI 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 119 NDIA----------------SSAVMGL-----------IETTR--------GLLPGAGGTQRLPRCLGVALAKELIFTGR 163
Cdd:PRK07659  88 SEIVvtlytmpkltisaihgPAAGLGLsialtadyviaDISAKlamnfigiGLIPDGGGHFFLQKRVGENKAKQIIWEGK 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 164 RLSGTEAHVLGLVNhAVAQNEEGDAAYQRARALAQEILpQAPIAVRLGKVAIDRGTEVDIasgMAIEGMCYAQNIPTRDR 243
Cdd:PRK07659 168 KLSATEALDLGLID-EVIGGDFQTAAKQKISEWLQKPL-KAMIETKQIYCELNRSQLEQV---LQLEKRAQYAMRQTADH 242
                        250
                 ....*....|....*...
gi 150378541 244 LEGMAAFREKRTPKFVGK 261
Cdd:PRK07659 243 KEGIRAFLEKRLPVFKGE 260
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
27-189 4.41e-16

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 77.60  E-value: 4.41e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  27 GSEIQVRALagpDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKERE---QMS 103
Cdd:PRK11730   5 GKTLQVDWL---EDGIAELVFDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSA-KDAFIVGADITEFLslfAAP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 104 EAEVGVFVQRLRGLMNDI-------------------------------ASSAVMGLIETTRGLLPGAGGTQRLPRCLGV 152
Cdd:PRK11730  81 EEELSQWLHFANSIFNRLedlpvptvaaingyalgggcecvlatdyrvaSPDARIGLPETKLGIMPGFGGTVRLPRLIGA 160
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 150378541 153 ALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAA 189
Cdd:PRK11730 161 DNALEWIAAGKDVRAEDALKVGAVDAVVAPEKLQEAA 197
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
35-261 1.78e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 71.24  E-value: 1.78e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  35 LAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK-EREQMSE------AEV 107
Cdd:PRK07468   8 IAVDARGVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVL-TGAGKSFCAGGDLGwMRAQMTAdratriEEA 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 108 GVFVQRLR----------------------GLMN--DIA---SSAVMGLIETTRGLLPGAGGTQRLPRcLGVALAKELIF 160
Cdd:PRK07468  87 RRLAMMLKalndlpkpligriqgqafgggvGLISvcDVAiavSGARFGLTETRLGLIPATISPYVVAR-MGEANARRVFM 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 161 TGRRLSGTEAHVLGLVNHAVAQnEEGDAAYQRaralaqEILPQ---APIAV-RLGKVAIDRGTEVDIAS-GMAIEGMcyA 235
Cdd:PRK07468 166 SARLFDAEEAVRLGLLSRVVPA-ERLDAAVEA------EVTPYlscAPGAVaAAKALVRALGAPIDEAViDATIEAL--A 236
                        250       260
                 ....*....|....*....|....*.
gi 150378541 236 QNIPTRDRLEGMAAFREKRTPKFVGK 261
Cdd:PRK07468 237 DTWETEEAREGIAAFFDKRAPAWRGG 262
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
34-258 3.62e-14

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 70.44  E-value: 3.62e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  34 ALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMseaeVGVFVQR 113
Cdd:PRK07327  14 RFDRPPPGVLEIVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIR-GEGKAFSAGGDLALVEEM----ADDFEVR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 114 LRgLMNDiASSAVMGLIE-------TTRGLLPGAG--------------------GTQRL------------PRCLGVAL 154
Cdd:PRK07327  89 AR-VWRE-ARDLVYNVINcdkpivsAIHGPAVGAGlvaalladisiaakdariidGHTRLgvaagdhaaivwPLLCGMAK 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 155 AKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAID---RGTEVDIASGMAIEG 231
Cdd:PRK07327 167 AKYYLLLCEPVSGEEAERIGLVSLAVDDDELLPKALEVAERLAA----GSQTAIRWTKYALNnwlRMAGPTFDTSLALEF 242
                        250       260
                 ....*....|....*....|....*..
gi 150378541 232 MCYAqnipTRDRLEGMAAFREKRTPKF 258
Cdd:PRK07327 243 MGFS----GPDVREGLASLREKRAPDF 265
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
41-217 4.65e-14

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 71.41  E-value: 4.65e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541   41 GITEILMNRPSAR-NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGAD---------LKEREQMSEaEVGVF 110
Cdd:TIGR02441  22 DVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADiqmiaacktAQEVTQLSQ-EGQEM 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  111 VQRLR-----------------GLMNDIA---------SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRR 164
Cdd:TIGR02441 101 FERIEksqkpivaaisgsclggGLELALAchyriatkdRKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKK 180
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 150378541  165 LSGTEAHVLGLVNHAVAQNEEG-DAAYQRARALAQEILPQAPIAVRLGKVAIDR 217
Cdd:TIGR02441 181 IRADRAKKMGIVDQLVDPLGPGlKPAEENTIEYLEEVAVKFAQGLANGKLSINR 234
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
39-260 5.09e-14

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 70.00  E-value: 5.09e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALgnVFVS--ELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE----REQMSEAEV----- 107
Cdd:PRK08258  24 DDGVATITLNRPERKNPL--TFESyaELRDLFRELVYADDVKAVVLT-GAGGNFCSGGDVHEiigpLTKMDMPELlaftr 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 108 --GVFVQRLRGLMNDIASS---------AVMGL-----IET---------TRGLLPGA--GGTQRLPRCLGVALAKELIF 160
Cdd:PRK08258 101 mtGDLVKAMRACPQPIIAAvdgvcagagAILAMasdlrLGTpsaktaflfTRVGLAGAdmGACALLPRIIGQGRASELLY 180
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 161 TGRRLSGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRgtEVDIASGMAIEGMCYAQNI-- 238
Cdd:PRK08258 181 TGRSMSAEEGERWGFFNRLV----EPEELLAEAQALARRLAAGPTFAHGMTKTMLHQ--EWDMGLEEAIEAEAQAQAIcm 254
                        250       260
                 ....*....|....*....|..
gi 150378541 239 PTRDRLEGMAAFREKRTPKFVG 260
Cdd:PRK08258 255 QTEDFRRAYEAFVAKRKPVFEG 276
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
39-204 9.81e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 68.77  E-value: 9.81e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE--REQMSEAEVG----VFVQ 112
Cdd:PRK08259  10 NGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVL-WGAGGTFCAGADLKAvgTGRGNRLHPSgdgpMGPS 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 113 RLR----------------GL-------MNDIASSAVMG---------LIEttrgllpgaGGTQRLPRCLGVALAKELIF 160
Cdd:PRK08259  89 RMRlskpviaavsgyavagGLelalwcdLRVAEEDAVFGvfcrrwgvpLID---------GGTVRLPRLIGHSRAMDLIL 159
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 150378541 161 TGRRLSGTEAHVLGLVNHAVAQNEegdaAYQRARALAQEI--LPQA 204
Cdd:PRK08259 160 TGRPVDADEALAIGLANRVVPKGQ----ARAAAEELAAELaaFPQT 201
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
36-216 7.65e-13

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 66.02  E-value: 7.65e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  36 AGPDQGITEILMNRPSArNALGNVFVSELLETLAQL-REDRQVRVLLFrsGVKGVFCAGADLKEREQMSEAEVGVFVQRL 114
Cdd:PRK05869  12 GSQDAGLATLLLSRPPT-NALTRQVYREIVAAANELgRRDDVAAVILY--GGHEIFSAGDDMPELRTLSAQEADTAARVR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 115 RGLMNDIAS-------------------------------SAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGR 163
Cdd:PRK05869  89 QQAVDAVAAipkptvaaitgyalgagltlalaadwrvsgdNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGR 168
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 150378541 164 RLSGTEAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAID 216
Cdd:PRK05869 169 FFDAEEALALGLIDEMVAP----DDVYDAAAAWARRFLDGPPHALAAAKAGIS 217
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
38-257 2.30e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 65.37  E-value: 2.30e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSEAEVGvFVQRLRGL 117
Cdd:PRK08290  10 VAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKH-FSAGHDLGSGTPGRDRDPG-PDQHPTLW 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 118 MNDIASSAVMGLIE---------TTR-------------------GLL------------------P----GAGGTQRL- 146
Cdd:PRK08290  88 WDGATKPGVEQRYArewevylgmCRRwrdlpkptiaqvqgaciagGLMlawvcdlivasddaffsdPvvrmGIPGVEYFa 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 147 -PRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVD--- 222
Cdd:PRK08290 168 hPWELGPRKAKELLFTGDRLTADEAHRLGMVNRVVPRDE----LEAETLELARRIAAMPPFGLRLTKRAVNQTLDAQgfr 243
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 150378541 223 --IASGMAIEGMCYAQN------IPTRDRLEGMAAFREKRTPK 257
Cdd:PRK08290 244 aaLDAVFDLHQLGHAHNaevggdRLGGADARGMADARKAAAAK 286
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
41-258 8.29e-12

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 63.76  E-value: 8.29e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQ---MSEAEVGVF----VQR 113
Cdd:PRK07396  22 GIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDQKVRGYggyVDDDGVPRLnvldLQR 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 114 L------------RG----------LMND--IAS-SAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 168
Cdd:PRK07396 102 LirtcpkpviamvAGyaiggghvlhLVCDltIAAdNAIFGQTGPKVGSFDGGYGASYLARIVGQKKAREIWFLCRQYDAQ 181
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 169 EAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQAPIAVRLGKVAIDrgTEVDIASGMA-IEG---MCYAQnipTRDRL 244
Cdd:PRK07396 182 EALDMGLVNTVVPLADLEKETVRWCR----EMLQNSPMALRCLKAALN--ADCDGQAGLQeLAGnatMLFYM---TEEAQ 252
                        250
                 ....*....|....
gi 150378541 245 EGMAAFREKRTPKF 258
Cdd:PRK07396 253 EGRNAFNEKRQPDF 266
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
41-260 2.47e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 62.10  E-value: 2.47e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGL-- 117
Cdd:PRK06072   9 GYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIV-TGEGRAFCVGADLSEfAPDFAIDLRETFYPIIREIrf 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 118 --------MNDIASSAVMGLIETTR-----------------GLLPGAGGTQRLPRcLGVALAKELIFTGRRLSGTEAHV 172
Cdd:PRK06072  88 sdkiyisaINGVTAGACIGIALSTDfkfasrdvkfvtafqrlGLASDTGVAYFLLK-LTGQRFYEILVLGGEFTAEEAER 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 173 LGLVnhavaqnEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFRE 252
Cdd:PRK06072 167 WGLL-------KISEDPLSDAEEMANRISNGPFQSYIAAKRMINLVLYNDLEEFLEYESAIQGYLGKTEDFKEGISSFKE 239

                 ....*...
gi 150378541 253 KRTPKFVG 260
Cdd:PRK06072 240 KREPKFKG 247
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
38-198 3.54e-11

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 61.52  E-value: 3.54e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGL 117
Cdd:PRK07110  11 VEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILT-GYPNYFATGGTQEGLLSLQTGKGTFTEANLYSL 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 118 MND-------------IASSAVMGL-----------IETTR----GLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTE 169
Cdd:PRK07110  90 ALNcpipviaamqghaIGGGLVLGLyadivvlsresVYTANfmkyGFTPGMGATAILPEKLGLALGQEMLLTARYYRGAE 169
                        170       180
                 ....*....|....*....|....*....
gi 150378541 170 AHVLGLVNHAVAQNEEGDAAYQRARALAQ 198
Cdd:PRK07110 170 LKKRGVPFPVLPRAEVLEKALELARSLAE 198
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
39-261 4.12e-11

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 61.67  E-value: 4.12e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDR-QVRVLLFRSGVKGvFCAGADLKER-EQMSEAEVGV------- 109
Cdd:PRK05981  11 DGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKaEVRCLVLTGAGRG-FCTGANLQGRgSGGRESDSGGdagaale 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 110 -----FVQRLRGLMNDIASS------------AVMG-LIETTR-----------GLLPGAGGTQRLPRCLGVALAKELIF 160
Cdd:PRK05981  90 tayhpFLRRLRNLPCPIVTAvngpaagvgmsfALMGdLILCARsayflqafrriGLVPDGGSTWLLPRLVGKARAMELSL 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 161 TGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAqeilpQAPiAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIP- 239
Cdd:PRK05981 170 LGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELA-----NGP-TVALGLIRKLYWDSPENDFEEQLNLEREAQRIAg 243
                        250       260
                 ....*....|....*....|...
gi 150378541 240 -TRDRLEGMAAFREKRTPKFVGK 261
Cdd:PRK05981 244 kTEDFKEGVGAFLQKRPAQFKGR 266
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
37-215 5.01e-11

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 61.14  E-value: 5.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  37 GPDQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSEAEVGVFVQR--- 113
Cdd:PRK07938   7 TPEPGIAEVTVDYPPV-NALPSAGWFALADAITAAGADPDTRVVVLRAEGRG-FNAGVDIKELQATPGFTALIDANRgcf 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 114 ---------------------------LRGLMNDIASS--AVMGLIETTRGLLPGAGGTQRLprcLGVALAKELIFTGRR 164
Cdd:PRK07938  85 aafravyecavpviaavhgfclgggigLVGNADVIVASddATFGLPEVDRGALGAATHLQRL---VPQHLMRALFFTAAT 161
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 150378541 165 LSGTEAHVLGLVnHAVAQNEEGDAAyqrARALAQEILPQAPIAVRLGKVAI 215
Cdd:PRK07938 162 ITAAELHHFGSV-EEVVPRDQLDEA---ALEVARKIAAKDTRVIRAAKEAL 208
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
34-254 6.72e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 60.82  E-value: 6.72e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  34 ALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQR 113
Cdd:PRK06143   9 GVTRDDRGVATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQASAEAFISR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 114 LRGLMNDI-------------------------------ASSAVMGLIETTRGlLPGAGGTQRLPRCLGVALAKELIFTG 162
Cdd:PRK06143  89 LRDLCDAVrhfpvpviaripgwclggglelaaacdlriaAHDAQFGMPEVRVG-IPSVIHAALLPRLIGWARTRWLLLTG 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 163 RRLSGTEAHVLGLVnHAVAQNEEGDAAYQRaraLAQEILPQAPIAVRLGKVAI----DRGTEVDIASGMAIEGMCYAQNI 238
Cdd:PRK06143 168 ETIDAAQALAWGLV-DRVVPLAELDAAVER---LAASLAGCGPQALRQQKRLLreweDMPLDVAIDDSVAEFGAAFLTGE 243
                        250
                 ....*....|....*.
gi 150378541 239 PTRDrlegMAAFREKR 254
Cdd:PRK06143 244 PQRH----MAAFLNRK 255
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
45-180 8.52e-11

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 60.95  E-value: 8.52e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541   45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRS-GVKGvFCAGADLKE-REQMSE---AEVGVFVQRLRGLMN 119
Cdd:pfam16113   4 ITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGaGERA-FCAGGDVRAlYEAAKAgggEAGRDFFREEYRLNY 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  120 DIASSA----------VMG------------------LI---ETTRGLLPGAGGTQRLPRC---LGVALAkeliFTGRRL 165
Cdd:pfam16113  83 LIATYPkpyvalmdgiVMGggvglsvhgsfrvvtertRFampETAIGLFPDVGGSYFLSRLpgeLGLYLA----LTGARL 158
                         170
                  ....*....|....*
gi 150378541  166 SGTEAHVLGLVNHAV 180
Cdd:pfam16113 159 NGADALAAGLATHYV 173
PLN02921 PLN02921
naphthoate synthase
39-258 3.72e-10

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 59.42  E-value: 3.72e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQ-----------MSEAEV 107
Cdd:PLN02921  74 GEGIAKITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGDQAVRGKdgyvgpddagrLNVLDL 153
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 108 GVFVQRL--------RG----------LMNDI---ASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 166
Cdd:PLN02921 154 QIQIRRLpkpviamvAGyavggghilhMVCDLtiaADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWFLARFYT 233
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 167 GTEAHVLGLVNHAV--AQNEEGDAAYQRaralaqEILPQAPIAVRLGKVAIDRGTevDIASGmaIEGMcyAQNIP----- 239
Cdd:PLN02921 234 ASEALKMGLVNTVVplDELEGETVKWCR------EILRNSPTAIRVLKSALNAAD--DGHAG--LQEL--GGNATllfyg 301
                        250
                 ....*....|....*....
gi 150378541 240 TRDRLEGMAAFREKRTPKF 258
Cdd:PLN02921 302 SEEGNEGRTAYLEGRAPDF 320
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
41-258 7.98e-10

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 57.91  E-value: 7.98e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLF-----RSGVKGVFCAGADLKEREQ---MSEAEVGVF-- 110
Cdd:COG0447   27 GIARIAINRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLtgngpSKDGGWAFCSGGDQRVRGRggyVYEDGVGRLni 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 111 --VQRLRGLMND------------------------IAS-SAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGR 163
Cdd:COG0447  107 leVQRLIRFMPKpviamvagwaiggghvlhvvcdltIASeNARFGQTGPDVGSFDAGYGSAYLARQVGQKKAREIWFLCR 186
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 164 RLSGTEAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQAPIAVRLGKVAIDRGTEvdiasGMAieG----------MC 233
Cdd:COG0447  187 QYSAQEALEMGLVNKVVPHAELEEEAVEWAR----EILEKSPTAIRMLKAAFNADDD-----GLA--GqqefageatrLA 255
                        250       260
                 ....*....|....*....|....*
gi 150378541 234 YAqnipTRDRLEGMAAFREKRTPKF 258
Cdd:COG0447  256 YM----TDEAQEGRDAFLEKRKPDF 276
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
39-261 5.25e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 55.03  E-value: 5.25e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRsGVKGVFCAGADLKEREQMSEaevgvFVQRLRGLM 118
Cdd:PRK07854   7 DGQVLTIELQRPERRNALNAELCEELREAVRKA-VDESARAIVLT-GQGTVFCAGADLSGDVYADD-----FPDALIEML 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 119 NDIaSSAVMGLIETTRGLLPGAgGTQ---------------------------------RLPRCLGVALAKELIFTGRRL 165
Cdd:PRK07854  80 HAI-DAAPVPVIAAINGPAIGA-GLQlamacdlrvvapeayfqfpvakygialdnwtirRLSSLVGGGRARAMLLGAEKL 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 166 SGTEAHVLGLVnhavaqNEEGDAAyqRARALAQEILPQAPIAVRLGKVAI-DRGTEVDIASG-MAIEGMCYAqnipTRDR 243
Cdd:PRK07854 158 TAEQALATGMA------NRIGTLA--DAQAWAAEIAGLAPLALQHAKRVLnDDGAIEEAWPAhKELFDKAWA----SQDA 225
                        250
                 ....*....|....*...
gi 150378541 244 LEGMAAFREKRTPKFVGK 261
Cdd:PRK07854 226 IEAQVARIEKRPPKFQGA 243
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
39-258 3.70e-08

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 53.10  E-value: 3.70e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFR----SGVKG--VFCAGADLKER------------- 99
Cdd:PRK08321  32 DQGTVRIAFDRPEVRNAFRPHTVDELYRALDHARMSPDVGCVLLTgngpSPKDGgwAFCSGGDQRIRgrdgyqyaegdea 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 100 EQMSEAEVGVF----VQRLRGLMNDIASSAVMG--------------LIETTR------------GLLPGAGGTQRLPRC 149
Cdd:PRK08321 112 DTVDPARAGRLhileVQRLIRFMPKVVIAVVPGwaaggghslhvvcdLTLASReharfkqtdadvGSFDGGYGSAYLARQ 191
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 150 LGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQAPIAVRLGKVA---IDRG-TEVDIAS 225
Cdd:PRK08321 192 VGQKFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETEALEWAR----EINGKSPTAMRMLKYAfnlTDDGlVGQQLFA 267
                        250       260       270
                 ....*....|....*....|....*....|...
gi 150378541 226 GMAIEgMCYAqnipTRDRLEGMAAFREKRTPKF 258
Cdd:PRK08321 268 GEATR-LAYM----TDEAQEGRDAFLEKRDPDW 295
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
45-184 1.67e-07

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 51.36  E-value: 1.67e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRS-GVKGvFCAGADLKE-----REQMSEAEVGVFVQRLR--- 115
Cdd:PRK05617  16 ITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGaGERG-FCAGGDIRAlyeaaRAGDPLAADRFFREEYRlna 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 116 ----------GLMNDIassaVMG-------------LIETTR--------GLLPGAGGTQRLPRCLGvALAKELIFTGRR 164
Cdd:PRK05617  95 liarypkpyiALMDGI----VMGggvgisahgshriVTERTKmampetgiGFFPDVGGTYFLSRAPG-ALGTYLALTGAR 169
                        170       180
                 ....*....|....*....|
gi 150378541 165 LSGTEAHVLGLVNHAVAQNE 184
Cdd:PRK05617 170 ISAADALYAGLADHFVPSAD 189
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
39-176 6.09e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 49.35  E-value: 6.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKgVFCAGADLKEREQMSEAEVGVFVQRLRGLM 118
Cdd:PRK07260   9 EDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGK-VFSVGGDLVEMKRAVDEDDVQSLVKIAELV 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 119 NDI--------------ASSAVMG-----------LIETTR----------GLLPGAGGTQRLPRCLGVALAKELIFTGR 163
Cdd:PRK07260  88 NEIsfaikqlpkpvimcVDGAVAGaaanmavaadfCIASTKtkfiqafvgvGLAPDAGGLFLLTRAIGLNRATHLAMTGE 167
                        170
                 ....*....|...
gi 150378541 164 RLSGTEAHVLGLV 176
Cdd:PRK07260 168 ALTAEKALEYGFV 180
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
39-260 9.64e-07

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 48.52  E-value: 9.64e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVR-VLLFRSGvkGVFCAGADLKE--REQMSEAEVGVFVQR-L 114
Cdd:PRK07827  13 DGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRaVVLTHTG--GTFCAGADLSEagGGGGDPYDAAVARAReM 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 115 RGLMNDIASSAV--------------MGLI-----------------ETTRGLLPGAGGTQRLPRCLGVALAKELIfTGR 163
Cdd:PRK07827  91 TALLRAIVELPKpviaaidghvraggFGLVgacdivvagpestfaltEARIGVAPAIISLTLLPRLSPRAAARYYL-TGE 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 164 RLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQeilPQAPIAV-RLGKVAIDRGTEVDiASGMAIEGmcyAQNIPTRD 242
Cdd:PRK07827 170 KFGAAEAARIGLVTAAADDVDAAVAALLADLRRGS---PQGLAESkALTTAAVLAGFDRD-AEELTEES---ARLFVSDE 242
                        250
                 ....*....|....*...
gi 150378541 243 RLEGMAAFREKRTPKFVG 260
Cdd:PRK07827 243 AREGMTAFLQKRPPRWAL 260
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
38-259 2.32e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 47.52  E-value: 2.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKE-----------------RE 100
Cdd:PRK05864  16 PRPEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRG-FSSGADHKSagvvphvegltrptyalRS 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 101 QMSEAEVGVFVQRLR------------------GLMNDI---ASSAVMGLIETTRGLLPGAGG-TQRLPRCLGVALAKEL 158
Cdd:PRK05864  95 MELLDDVILALRRLHqpviaavngpaiggglclALAADIrvaSSSAYFRAAGINNGLTASELGlSYLLPRAIGSSRAFEI 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 159 IFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTevdIASGMAIEGMcyAQ-- 236
Cdd:PRK05864 175 MLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAGFSRPGIELTKRTLWSGLDAAS---LEAHMQAEGL--GQlf 249
                        250       260
                 ....*....|....*....|....
gi 150378541 237 -NIPTRDRLEGMAAFREKRTPKFV 259
Cdd:PRK05864 250 vRLLTANFEEAVAARAEKRPPVFT 273
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
40-256 7.83e-06

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 45.95  E-value: 7.83e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  40 QGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSE----------AEVGV 109
Cdd:PRK05674  14 RGFATLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLR-GRGRHFSAGADLAWMQQSADldyntnlddaRELAE 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 110 FVQRLRGL------------------------MNDIASSAVMGLIETTRGLLPgAGGTQRLPRCLGVALAKELIFTGRRL 165
Cdd:PRK05674  93 LMYNLYRLkiptlavvqgaafggalglisccdMAIGADDAQFCLSEVRIGLAP-AVISPFVVKAIGERAARRYALTAERF 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 166 SGTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKvaiDRGTEVDiASGMAIEGMCYAQNIPTRDRL- 244
Cdd:PRK05674 172 DGRRARELGLLAESYPAAE----LEAQVEAWIANLLLNSPQALRASK---DLLREVG-DGELSPALRRYCENAIARIRVs 243
                        250
                 ....*....|....*.
gi 150378541 245 ----EGMAAFREKRTP 256
Cdd:PRK05674 244 aegqEGLRAFLEKRTP 259
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
38-200 2.12e-05

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 45.03  E-value: 2.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKE-REQMSEAEVG----VFVQ 112
Cdd:PRK08272  16 VTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKG-FCAGYDLSAyAEGSSSGGGGgaypGKRQ 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 113 RLRGLMNDIASSAV--MGLIETTRGLL-------PG---------AGGTQRLPRC------------------------- 149
Cdd:PRK08272  95 AVNHLPDDPWDPMIdyQMMSRFVRGFMslwhahkPTvakvhgycvAGGTDIALHCdqviaaddakigypptrvwgvpatg 174
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 150378541 150 -----LGVALAKELIFTGRRLSGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEI 200
Cdd:PRK08272 175 mwayrLGPQRAKRLLFTGDCITGAQAAEWGLAVEAV----PPEELDERTERLVERI 226
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
39-184 2.29e-05

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 44.67  E-value: 2.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLlfrSGVKGVFCAGADLKE--------REQMSEAEV--- 107
Cdd:PRK07112  11 QGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHAATIVVL---EGLPEVFCFGADFSAiaekpdagRADLIDAEPlyd 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 108 -------GVFV--QRLRGLMN----------DIA---SSAVMGLIETTRGLLPgAGGTQRLPRCLGVALAKELIFTGRRL 165
Cdd:PRK07112  88 lwhrlatGPYVtiAHVRGKVNaggigfvaasDIViadETAPFSLSELLFGLIP-ACVLPFLIRRIGTQKAHYMTLMTQPV 166
                        170
                 ....*....|....*....
gi 150378541 166 SGTEAHVLGLVNHAVAQNE 184
Cdd:PRK07112 167 TAQQAFSWGLVDAYGANSD 185
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
20-198 3.00e-05

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 44.49  E-value: 3.00e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  20 ASDGAAGGSEIQVRAlagpdQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGV-KGVFCAGADLKE 98
Cdd:PLN03214   5 SPPGATPGVRVDRRP-----GGIAVVWLAKEPV-NSMTLAMWRSLDDALTALENDPTVRGVVFASGLrRDVFTAGNDIAE 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  99 REQMSEAEV---------GVFVQRL-----------RG----------LMND---IASSAVMGLIETTRGL-LPGAGGTQ 144
Cdd:PLN03214  79 LYAPKTSAAryaefwltqTTFLVRLlrsrlatvcaiRGacpaggcavsLCCDyrlQTTEGTMGLNEVALGIpVPKFWARL 158
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 150378541 145 RLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQ 198
Cdd:PLN03214 159 FMGRVIDRKVAESLLLRGRLVRPAEAKQLGLIDEVVPAAALMEAAASAMERALK 212
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
45-97 3.94e-05

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 44.41  E-value: 3.94e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 150378541  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLK 97
Cdd:PLN02874  24 ITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIK-GAGRAFSAGGDLK 75
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
31-180 4.28e-05

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 44.32  E-value: 4.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  31 QVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGAD----LKEREQ----- 101
Cdd:PLN02988   8 QSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILK-GHGRAFCAGGDvaavVRDIEQgnwrl 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 102 -----------------MSEAEVGVFVQ---------RLRGLMNDIASSAVMGLIETTRGLLPGAGGTQRLPRCLGVaLA 155
Cdd:PLN02988  87 ganffsdeymlnyvmatYSKAQVSILNGivmgggagvSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF-FG 165
                        170       180
                 ....*....|....*....|....*
gi 150378541 156 KELIFTGRRLSGTEAHVLGLVNHAV 180
Cdd:PLN02988 166 EYVGLTGARLDGAEMLACGLATHFV 190
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
31-189 6.01e-05

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 43.36  E-value: 6.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  31 QVRALAGPDQGITEILMnRPSARNALGNVFVSELLETLAQLREDRQVRVLLFR-----SGVKGVFCAGADL--------- 96
Cdd:PRK08788  16 QLRVYYEEERNVMWMYM-RAQPRPCFNLELLDDIMNLQRAIRQRLDDSGLPVDfwvlaSDVPGVFNLGGDLalfaelira 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  97 KEREQM---SEAEVGVFVQRLRGLMNDIAS--------------------------SAVMGLIETTRGLLPGAGGTQRLP 147
Cdd:PRK08788  95 GDRDALlayARACVDGVHAFHRGFGAGAISialvqgdalgggfeaalshhtiiaerGAKMGFPEILFNLFPGMGAYSFLA 174
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 150378541 148 RCLGVALAKELIFTGRRLSGTEAHVLGLVnHAVAQNEEGDAA 189
Cdd:PRK08788 175 RRVGPKLAEELILSGKLYTAEELHDMGLV-DVLVEDGQGEAA 215
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
41-250 1.95e-04

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 41.70  E-value: 1.95e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE--REQMS----EAEVGVFVQRL 114
Cdd:PRK06023  15 GVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFL-GTEGCFSAGNDMQDflAAAMGgtsfGSEILDFLIAL 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 115 RGLMNDIAsSAVMGL---------------IETTR----------GLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTE 169
Cdd:PRK06023  94 AEAEKPIV-SGVDGLaigigttihlhcdltFASPRslfrtpfvdlALVPEAGSSLLAPRLMGHQRAFALLALGEGFSAEA 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 170 AHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIdRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAA 249
Cdd:PRK06023 173 AQEAGLIWKIVDE----EAVEAETLKAAEELAAKPPQALQIARDLM-RGPREDILARIDEEAKHFAARLKSAEARAAFEA 247

                 .
gi 150378541 250 F 250
Cdd:PRK06023 248 F 248
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
39-197 1.24e-03

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 39.32  E-value: 1.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLkerEQMSEAEVGVFVQRLRGL- 117
Cdd:PRK05870  10 DDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVV-TGAGKAFCAGADL---TALGAAPGRPAEDGLRRIy 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150378541 118 -------------------------MN-------DIASSAVMGLIETTR-GLLPGAGGTQRLPRCLGVALAKELIFTGRR 164
Cdd:PRK05870  86 dgflavascplptiaavngaavgagLNlalaadvRIAGPKALFDARFQKlGLHPGGGATWMLQRAVGPQVARAALLFGMR 165
                        170       180       190
                 ....*....|....*....|....*....|...
gi 150378541 165 LSGTEAHVLGLVNHAVaqNEEGDAAYQRARALA 197
Cdd:PRK05870 166 FDAEAAVRHGLALMVA--DDPVAAALELAAGPA 196
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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