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Conserved domains on  [gi|254281331|ref|NP_061349|]
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neutral amino acid transporter A isoform 1 [Mus musculus]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
52-496 7.33e-111

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 335.55  E-value: 7.33e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  52 VLVGAGMGAALrGLQLTRTQITYLAFPGEMLLRMLRMIILPLVVCSLVSGAASL-DASSLGRLGGIAVAYFGLTTLSASA 130
Cdd:COG1301    9 ILIALVLGILL-GLLLPELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTLLYFLVTTTIALV 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 131 LAVALAFIIKPGAGaqtlqsssLGLENSGPPPVSKETVDSFLDLLRNLFPSNlVVAAFTTSatdytvvthntssgnvtke 210
Cdd:COG1301   88 IGLVVANLFQPGAG--------LNLDLADAAAAEAAEAPSLLDFLLNIIPSN-IFEAFAEG------------------- 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 211 kipvvtdvegmNILGLVLFALVLGVALKKLGPEGEDLIRFFNSFNEATMVLVSWIMWYVPIGIMFLIGSKIVEMkDIVML 290
Cdd:COG1301  140 -----------NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDAL 207
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 291 VtSLGKYIFASMLGHVIHGGIVLPLVYFAFTRKNPFTFLLGLLTPFATAFATCSSSATLPSMMKCIEENNGVDKRISRFI 370
Cdd:COG1301  208 G-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFV 286
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 371 LPIGATVNMDGAAIFQCVAAVFIAQLNNVDLNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPTHDLSLILA 450
Cdd:COG1301  287 LPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILG 366
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*.
gi 254281331 451 VDWIVDRTTTVVNVEGDALGAgilnhlnqKVVKKGEQELQEVKVEA 496
Cdd:COG1301  367 IDRILDMARTAVNVTGDAVAT--------VVVAKWEGELDREKLNA 404
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
52-496 7.33e-111

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 335.55  E-value: 7.33e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  52 VLVGAGMGAALrGLQLTRTQITYLAFPGEMLLRMLRMIILPLVVCSLVSGAASL-DASSLGRLGGIAVAYFGLTTLSASA 130
Cdd:COG1301    9 ILIALVLGILL-GLLLPELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTLLYFLVTTTIALV 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 131 LAVALAFIIKPGAGaqtlqsssLGLENSGPPPVSKETVDSFLDLLRNLFPSNlVVAAFTTSatdytvvthntssgnvtke 210
Cdd:COG1301   88 IGLVVANLFQPGAG--------LNLDLADAAAAEAAEAPSLLDFLLNIIPSN-IFEAFAEG------------------- 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 211 kipvvtdvegmNILGLVLFALVLGVALKKLGPEGEDLIRFFNSFNEATMVLVSWIMWYVPIGIMFLIGSKIVEMkDIVML 290
Cdd:COG1301  140 -----------NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDAL 207
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 291 VtSLGKYIFASMLGHVIHGGIVLPLVYFAFTRKNPFTFLLGLLTPFATAFATCSSSATLPSMMKCIEENNGVDKRISRFI 370
Cdd:COG1301  208 G-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFV 286
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 371 LPIGATVNMDGAAIFQCVAAVFIAQLNNVDLNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPTHDLSLILA 450
Cdd:COG1301  287 LPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILG 366
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*.
gi 254281331 451 VDWIVDRTTTVVNVEGDALGAgilnhlnqKVVKKGEQELQEVKVEA 496
Cdd:COG1301  367 IDRILDMARTAVNVTGDAVAT--------VVVAKWEGELDREKLNA 404
SDF pfam00375
Sodium:dicarboxylate symporter family;
44-477 1.24e-107

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 326.79  E-value: 1.24e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331   44 LVLLTVSGVLVGAGMGAALRGLqltrtqITYLAFPGEMLLRMLRMIILPLVVCSLVSGAASL-DASSLGRLGGIAVAYFG 122
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPEL------AAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFL 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  123 LTTLSASALAVALAFIIKPGAGAQTLQSSSLGLENSGPPpvsketvdSFLDLLRNLFPSNLVVAAFTTsatdytvvthnt 202
Cdd:pfam00375  75 VTTAIAALIGLLVANVFQPGSGLALIAASLKEAKAAEAP--------SLLDFILNIIPSNIFEALAEG------------ 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  203 ssgnvtkekipvvtdvegmNILGLVLFALVLGVALKKLGPEGEDLIRFFNSFNEATMVLVSWIMWYVPIGIMFLIGSKIV 282
Cdd:pfam00375 135 -------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVG 195
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  283 EMkdIVMLVTSLGKYIFASMLGHVIHGGIVLPLVYFAFTRKNPFTFLLGLLTPFATAFATCSSSATLPSMMKCIEENNGV 362
Cdd:pfam00375 196 TY--GLGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGV 273
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  363 DKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVDLNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPT 442
Cdd:pfam00375 274 SESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPL 353
                         410       420       430
                  ....*....|....*....|....*....|....*
gi 254281331  443 HDLSLILAVDWIVDRTTTVVNVEGDALGAGILNHL 477
Cdd:pfam00375 354 EGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
49-511 2.14e-37

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 142.73  E-value: 2.14e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  49 VSGVLVGA---GMGAALRGLqltrtqitylafpGEMLLRMLRMIILPLVVCSLVSGAASL-DASSLGRLGGIAVAYFGLT 124
Cdd:PRK01663  18 IIGILLGHfypELGAQMKPL-------------GDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKALLYFEIV 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 125 TLSASALAVALAFIIKPGAG----AQTLQSSSLGLEnsgpppVSKETVDSFLDLLRNLFPSNlVVAAFTTSatdytvvth 200
Cdd:PRK01663  85 STIALIIGLIVVNVVQPGAGmnidPATLDAKAVAQY------AAQAHEQGTVDFLMDIIPTT-VVGAFASG--------- 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 201 ntssgnvtkekipvvtdvegmNILGLVLFALVLGVALKKLGPEGEDLIRFFNSFNEATMVLVSWIMWYVPIG----IMFL 276
Cdd:PRK01663 149 ---------------------DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVNMIMKLAPIGafgaMAFT 207
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 277 IGS-KIVEMKDIVMLVTSLgkYIFASMLGHVIHGGIvlpLVYFAFtrkNPFTFLLGLLTPFATAFATCSSSATLPSMMKC 355
Cdd:PRK01663 208 IGKyGVGSLVQLGQLIGCF--YITCILFVFVVLGAI---ARLTGF---SIFKFIRYIKEELLIVLGTSSSESALPRMMEK 279
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 356 IeENNGVDKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVDLNAGQIFTILVTATASSVGAAGVPAGGVLTIAIIL 435
Cdd:PRK01663 280 M-EKLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVTGSGFIVLAATL 358
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 254281331 436 EAIG-LPTHDLSLILAVDWIVDrtttvvnvEGDALGAGILNHLNQKVVKKGEQELQEVKVEAIPNSKSEEETSPLVT 511
Cdd:PRK01663 359 SAVPhIPVAGLALILGIDRFMS--------EARALTNLIGNGVATVVVAKWEKELDREKLDRVLNGRAPDGKTEEVS 427
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
52-496 7.33e-111

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 335.55  E-value: 7.33e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  52 VLVGAGMGAALrGLQLTRTQITYLAFPGEMLLRMLRMIILPLVVCSLVSGAASL-DASSLGRLGGIAVAYFGLTTLSASA 130
Cdd:COG1301    9 ILIALVLGILL-GLLLPELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTLLYFLVTTTIALV 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 131 LAVALAFIIKPGAGaqtlqsssLGLENSGPPPVSKETVDSFLDLLRNLFPSNlVVAAFTTSatdytvvthntssgnvtke 210
Cdd:COG1301   88 IGLVVANLFQPGAG--------LNLDLADAAAAEAAEAPSLLDFLLNIIPSN-IFEAFAEG------------------- 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 211 kipvvtdvegmNILGLVLFALVLGVALKKLGPEGEDLIRFFNSFNEATMVLVSWIMWYVPIGIMFLIGSKIVEMkDIVML 290
Cdd:COG1301  140 -----------NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDAL 207
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 291 VtSLGKYIFASMLGHVIHGGIVLPLVYFAFTRKNPFTFLLGLLTPFATAFATCSSSATLPSMMKCIEENNGVDKRISRFI 370
Cdd:COG1301  208 G-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFV 286
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 371 LPIGATVNMDGAAIFQCVAAVFIAQLNNVDLNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPTHDLSLILA 450
Cdd:COG1301  287 LPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILG 366
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*.
gi 254281331 451 VDWIVDRTTTVVNVEGDALGAgilnhlnqKVVKKGEQELQEVKVEA 496
Cdd:COG1301  367 IDRILDMARTAVNVTGDAVAT--------VVVAKWEGELDREKLNA 404
SDF pfam00375
Sodium:dicarboxylate symporter family;
44-477 1.24e-107

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 326.79  E-value: 1.24e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331   44 LVLLTVSGVLVGAGMGAALRGLqltrtqITYLAFPGEMLLRMLRMIILPLVVCSLVSGAASL-DASSLGRLGGIAVAYFG 122
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPEL------AAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFL 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  123 LTTLSASALAVALAFIIKPGAGAQTLQSSSLGLENSGPPpvsketvdSFLDLLRNLFPSNLVVAAFTTsatdytvvthnt 202
Cdd:pfam00375  75 VTTAIAALIGLLVANVFQPGSGLALIAASLKEAKAAEAP--------SLLDFILNIIPSNIFEALAEG------------ 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  203 ssgnvtkekipvvtdvegmNILGLVLFALVLGVALKKLGPEGEDLIRFFNSFNEATMVLVSWIMWYVPIGIMFLIGSKIV 282
Cdd:pfam00375 135 -------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVG 195
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  283 EMkdIVMLVTSLGKYIFASMLGHVIHGGIVLPLVYFAFTRKNPFTFLLGLLTPFATAFATCSSSATLPSMMKCIEENNGV 362
Cdd:pfam00375 196 TY--GLGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGV 273
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  363 DKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVDLNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPT 442
Cdd:pfam00375 274 SESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPL 353
                         410       420       430
                  ....*....|....*....|....*....|....*
gi 254281331  443 HDLSLILAVDWIVDRTTTVVNVEGDALGAGILNHL 477
Cdd:pfam00375 354 EGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
49-511 2.14e-37

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 142.73  E-value: 2.14e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  49 VSGVLVGA---GMGAALRGLqltrtqitylafpGEMLLRMLRMIILPLVVCSLVSGAASL-DASSLGRLGGIAVAYFGLT 124
Cdd:PRK01663  18 IIGILLGHfypELGAQMKPL-------------GDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKALLYFEIV 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 125 TLSASALAVALAFIIKPGAG----AQTLQSSSLGLEnsgpppVSKETVDSFLDLLRNLFPSNlVVAAFTTSatdytvvth 200
Cdd:PRK01663  85 STIALIIGLIVVNVVQPGAGmnidPATLDAKAVAQY------AAQAHEQGTVDFLMDIIPTT-VVGAFASG--------- 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 201 ntssgnvtkekipvvtdvegmNILGLVLFALVLGVALKKLGPEGEDLIRFFNSFNEATMVLVSWIMWYVPIG----IMFL 276
Cdd:PRK01663 149 ---------------------DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVNMIMKLAPIGafgaMAFT 207
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 277 IGS-KIVEMKDIVMLVTSLgkYIFASMLGHVIHGGIvlpLVYFAFtrkNPFTFLLGLLTPFATAFATCSSSATLPSMMKC 355
Cdd:PRK01663 208 IGKyGVGSLVQLGQLIGCF--YITCILFVFVVLGAI---ARLTGF---SIFKFIRYIKEELLIVLGTSSSESALPRMMEK 279
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 356 IeENNGVDKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVDLNAGQIFTILVTATASSVGAAGVPAGGVLTIAIIL 435
Cdd:PRK01663 280 M-EKLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVTGSGFIVLAATL 358
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 254281331 436 EAIG-LPTHDLSLILAVDWIVDrtttvvnvEGDALGAGILNHLNQKVVKKGEQELQEVKVEAIPNSKSEEETSPLVT 511
Cdd:PRK01663 359 SAVPhIPVAGLALILGIDRFMS--------EARALTNLIGNGVATVVVAKWEKELDREKLDRVLNGRAPDGKTEEVS 427
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
79-503 2.26e-33

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 131.33  E-value: 2.26e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  79 GEMLLRMLRMIILPLVVCSLVSGAASL-DASSLGRLGGIAVAYFGLTTLSASALAVALAFIIKPGAGA----QTLQSSSL 153
Cdd:PRK13027  37 GDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKVGRVGLKAVIYFEVMTTIALVIGLVLAYLTGPGVGMnidlRSLDAASL 116
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 154 GLENSgpppvSKETVDSFLDLLRNLFPsNLVVAAFTTSatdytvvthntssgnvtkekipvvtdvegmNILGLVLFALVL 233
Cdd:PRK13027 117 AGYAK-----NAQSLKGTAGFLLKLIP-TTAVDAFAKG------------------------------DILQVLLFSVLF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 234 GVALKKLGPEGEDLIRFFNSFNEATMVLVSWIMWYVPIG----IMFLIGS-KIVEMKDIVMLVtslGKYIFASMLGHVIH 308
Cdd:PRK13027 161 GSALSLLGERAKRVNRLIDELSHVLFRIMGFIIKLAPLGvlgaIAFTTGKyGVGSLKQLGMLV---AVFYLTCFVFVVVV 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 309 GGIVLPLVYFAFtrknpFTFLLGLLTPFATAFATCSSSATLPSMMKCIeENNGVDKRISRFILPIGATVNMDGAAIFQCV 388
Cdd:PRK13027 238 LGAVMRLAGFSV-----FKLIRYLREELLIVLGTASSDAVLPQVMRKL-EHMGIKDSTVGLVIPTGYSFNLDGFSIYLTL 311
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 389 AAVFIAQLNNVDLNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIG-LPTHDLSLILAVDWIVDrtttvvnvEGD 467
Cdd:PRK13027 312 AAVFIAQATNTPLSMHDLITILLVSLVTSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMG--------IAR 383
                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 254281331 468 ALGAGILNHLNQKVVKKGEQELQEVKVEAIPNSKSE 503
Cdd:PRK13027 384 ALTNLIGNCVATVVVAVWENDIDRARAQAVLNGELR 419
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
51-508 6.26e-33

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 130.65  E-value: 6.26e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  51 GVLVGAGMGAALRGLQLTRTQI--TYLAFPGEMLLRMLRMIILPLVVCSLVSGAASL-DASSLGRLGGIAVAYFGLTTLS 127
Cdd:PRK11283  15 ALVLGILLGAYLHYHSDSRDWLvsNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVITTV 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 128 ASALAVALAFIIKPGAGaqtLQSSSLGLENSGPPPVSKETVDS----FLDLLRNLFPSNLVVAAfttsatdytvvthnts 203
Cdd:PRK11283  95 AIILGITLANVFQPGAG---IDMSQLATVDISKYQSTTEEVQShshgLMGTILSLIPTNIFASM---------------- 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 204 sgnVTKEKIPVVtdvegmnilglvLFALVLGVALKKLGPEGED-LIRFFNSFNEATMVLVSWIMWYVPIGIMFLIGSKIV 282
Cdd:PRK11283 156 ---AKGEMLPII------------FFSVLFGLGLSSLPATHREpLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVA 220
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 283 EMKDIVMLvtSLGKYIFASMLGHVIHGGIVLPLVYFAFtRKNPFTFLLGLLTPFATAFATCSSSATLPSMMKCIEENnGV 362
Cdd:PRK11283 221 NFGFASLW--PLAKLVLLVYFAILFFALVVLGIVARLC-GLSIWILIRILKDELILAYSTASSETVLPRIIEKMEAY-GA 296
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 363 DKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVDLNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPT 442
Cdd:PRK11283 297 PKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPL 376
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 254281331 443 HDLSLILAVDWIVDRTTTVVNVEGDALGAgilnhlnqKVVKKGEQELQEVKVEAIPNSKSEEETSP 508
Cdd:PRK11283 377 EGLAFIAGVDRILDMARTALNVVGNALAV--------LVIAKWEHKFDRKKALAYEREVLGKFDKT 434
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
43-481 2.28e-20

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 93.74  E-value: 2.28e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331  43 ALVLltvsGVLVGAGMGAAL-RGLQLTRTQITYLAFPGEMLLRMLRMIILPLVVCSLVSGAASL-DASSLGRLGGIAVAY 120
Cdd:COG1823   37 GLGL----GILFGLILQLIYgAGSPVIKQSIDWFNIVGNGYVRLLQMIVMPLVFVSILSAITKLkNASSLGKISGLIIGI 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 121 FGLTTLSASALAVALAFI-------IKPGAG----AQTLQSSSLGLENSgpppvsketvdSFLDLLRNLFPSNlVVAAFT 189
Cdd:COG1823  113 LLGTTAIAALVGILVALLfgltaegLTQGAAetarGEALEERLGEVEDL-----------SLPQQILSFIPTN-PFADLT 180
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 190 TSatdytvvtHNTSsgnvtkekipvvtdvegmnILGLVLFALVLGVA---LKKLGPE-GEDLIRFFNSFNEATMVLVSWI 265
Cdd:COG1823  181 GA--------RPTS-------------------TIAVVIFAAFLGIAalgLRRKKPEqAETFLKGIDALQAIVMRLVRLV 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 266 MWYVPIGIMFLIgSKIV---EMKDIVmlvtSLGKYIFASMLG----HVIHGGIVlplvyfAFTRKNPFTFLLGLLTPFAT 338
Cdd:COG1823  234 LRLTPYGVLALM-TKVVatsDFADIL----NLGKFVVASYVAliimFIVHLLLL------ALAGLNPLTYFKKVWPVLTF 302
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 339 AFATCSSSATLPSMMKCIEENNGVDKRISRFILPIGATVNMDG-AAIFQCVAAVFIAQLNNVD-LNAGQIFTILVTATAS 416
Cdd:COG1823  303 AFTSRSSAGTIPLNIETQTKRLGVPEGIANFAASFGATIGQNGcAGIYPAMLAVMIAPTVGINpLDPSFILTLIAVVTIS 382
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 254281331 417 SVGAAGVpaGGVLTIA--IILEAIGLPTHDLSLILAVDWIVDRTTTVVNVEGdALGAG-----ILNHLNQKV 481
Cdd:COG1823  383 SFGVAGV--GGGATFAalIVLSAMGLPVALAGLLISIEPLIDMGRTALNVSG-SMTAGtvtsrLLGQLDKDI 451
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
222-469 1.80e-13

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 71.23  E-value: 1.80e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 222 NILGLVLFALVLGVALKKLGPEGEDLIRffnSFNEATMVLVSWIMWYVPIGIMFLIGSKIVEMKdiVMLVTSLGKYIFAS 301
Cdd:PRK14695  60 NYIGILSWAVIFGIAMREASKNSKELLK---TIADVTSKIVEWIINLAPFGILGLVFKTISDKG--VGSLANYGILLVLL 134
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 302 MLGHVIHGGIVLPLVYFAFTRKNPFTFLLGLL-TPFATAFATCSSSATLPSMMKcIEENNGVDKRISRFILPIGATVNMD 380
Cdd:PRK14695 135 VTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCLrVSGVTAFFTRSSATNIPVNMK-LCHDLGLNPDTYSVSIPLGSTINMA 213
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 381 GAAIFQCVAAVFIAQLNNVDLNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPTHDLSLILAVDWIV----D 456
Cdd:PRK14695 214 GVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIgviqD 293
                        250
                 ....*....|...
gi 254281331 457 RTTTVVNVEGDAL 469
Cdd:PRK14695 294 SCETALNSSTDVL 306
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
222-431 1.90e-12

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 69.12  E-value: 1.90e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 222 NILGLVLFALVLGVALKKLGPEGEDLirfFNSFNEATMVLVSWIMWYVPIGIMFLIGSKIVE------MKDIVMLVTSLG 295
Cdd:PRK13628 146 NYIGILAWAIGLGLALRHASDTTKNV---VNDLSEAVSQIVKWVIRFAPIGIFGLVASTLAEtgfsalAGYAQLLAVLVG 222
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 296 KYIFASMlghvihggIVLPLVYFAFTRKNPFTFLLGLLTPFA-TAFATCSSSATLPSMMK-CieENNGVDKRISRFILPI 373
Cdd:PRK13628 223 CMLFVAL--------VVNPLIVFWKIRRNPYPLVFTCLRESGvTAFFTRSSAANIPVNMAlC--EKLGLDEDTYSVSIPL 292
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 254281331 374 GATVNMDGAAIFQCVAAVFIAQLNNVDLNAGQIFTILVTATASSVGAAGVPAGGVLTI 431
Cdd:PRK13628 293 GATINMAGAAITITVLTLAAVHTLGIPVDLPTALLLSVVAAISACGASGVAGGSLLLI 350
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
222-431 7.25e-12

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 67.12  E-value: 7.25e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 222 NILGLVLFALVLGVALKKLGPEGEDLirfFNSFNEATMVLVSWIMWYVPIGIMFLIGSKIVE-----MKDIVMLVTSL-G 295
Cdd:COG3633  145 NYIGILAWAIGLGLALRHASDTTKTV---LSDLSDAVSKIVRWVIRFAPLGIFGLVASTVATtgfsaLLGYAHLLAVLvG 221
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281331 296 KYIFASMlghvihggIVLPLVYFAFTRKNPFTFLLGLLTPFA-TAFATCSSSATLPSMMK-CieENNGVDKRISRFILPI 373
Cdd:COG3633  222 CMLFVAL--------VVNPLIVFLKIRRNPYPLVFTCLRESGiTAFFTRSSAANIPVNMAlC--EKLGLDEDTYSVSIPL 291
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 254281331 374 GATVNMDGAAIFQCVAAVFIAQLNNVDLNAGQIFTILVTATASSVGAAGVPAGGVLTI 431
Cdd:COG3633  292 GATINMAGAAITITVLTLAAVHTLGIEVDLPTALLLSVVAAVSACGASGVAGGSLLLI 349
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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