NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|46249404|ref|NP_061951|]
View 

UDP-glucuronosyltransferase 1A5 precursor [Homo sapiens]

Protein Classification

UDP-glycosyltransferase family protein( domain architecture ID 11989770)

UDP-glycosyltransferase family protein similar to UDP-glucuronosyltransferase (UDPGT), which is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds

EC:  2.4.-.-
Gene Ontology:  GO:0008194|GO:0006486
PubMed:  12691742|10521532|16037492
SCOP:  3001586

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
29-525 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


:

Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 866.72  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404    29 GKVLVVPTDGSHWLSMREALRDLHARGHQVVVLTLEVNMYIK--EENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHL 106
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGpgKPSNLKFETYPTSATKEELENPFPKRQMQWFEEASF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   107 LmKFSRRMAIMNNMSLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDLDFKGT- 185
Cdd:pfam00201  81 G-TVWSYFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSg 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   186 QCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQREVSVVDLVSHASVWLFRGDFVMDY 265
Cdd:pfam00201 160 GLPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLGRPVTLPELMSKASVWLIRSYWDLEF 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   266 PRPIMPNMVFIGGINCANGKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSN 345
Cdd:pfam00201 240 PRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPST 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   346 LANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLE 425
Cdd:pfam00201 320 LGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLL 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   426 NALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAF 505
Cdd:pfam00201 400 NALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAF 479

                         490       500
                  ....*....|....*....|
gi 46249404   506 ITFKCCAYGYRKCLGKKGRV 525
Cdd:pfam00201 480 ITFKCCLFGYRKFVGKKKRV 499
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
29-525 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 866.72  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404    29 GKVLVVPTDGSHWLSMREALRDLHARGHQVVVLTLEVNMYIK--EENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHL 106
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGpgKPSNLKFETYPTSATKEELENPFPKRQMQWFEEASF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   107 LmKFSRRMAIMNNMSLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDLDFKGT- 185
Cdd:pfam00201  81 G-TVWSYFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSg 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   186 QCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQREVSVVDLVSHASVWLFRGDFVMDY 265
Cdd:pfam00201 160 GLPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLGRPVTLPELMSKASVWLIRSYWDLEF 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   266 PRPIMPNMVFIGGINCANGKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSN 345
Cdd:pfam00201 240 PRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPST 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   346 LANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLE 425
Cdd:pfam00201 320 LGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLL 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   426 NALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAF 505
Cdd:pfam00201 400 NALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAF 479

                         490       500
                  ....*....|....*....|
gi 46249404   506 ITFKCCAYGYRKCLGKKGRV 525
Cdd:pfam00201 480 ITFKCCLFGYRKFVGKKKRV 499
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 30-447 2.41e-74

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 241.30  E-value: 2.41e-74
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  30 KVLVVPTDG-SHWLSMREALRDLHARGHQVVVLTLEVNMyIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLM 108
Cdd:cd03784   2 RILFVPFPGqGHVNPMLPLAKALAARGHEVTVATPPFNF-ADLVEAAGLTFVPVGDDPDELELDSETNLGPDSLLELLRR 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404 109 KFSRRMAIMnnmsliihRSCVELLhnealirhLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDLDFkgtqCP 188
Cdd:cd03784  81 LLKAADELL--------DDLLAAL--------RSSWKPDLVIADPFAYAGPLVAEELGIPSVRLFTGPATLLSA----YL 140

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404 189 NPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLaselfqREVSVVDLVSHASVWLfrgdfvmdYPRP 268
Cdd:cd03784 141 HPFGVLNLLLSSLLEPELFLDPLLEVLDRLRERLGLPPFSLVLLLL------RLVPPLYVIGPTFPSL--------PPDR 206

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404 269 IMPNMVFIGGINCANGKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPS---N 345
Cdd:cd03784 207 PRLPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVGPDPLGgleR 286

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404 346 LANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLE 425
Cdd:cd03784 287 LPDNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEELA 366

                       410       420
                ....*....|....*....|..
gi 46249404 426 NALKAVINDKSYKENIMRLSSL 447
Cdd:cd03784 367 KAVREVLEDESYRRAAELLAEL 388
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 262-508 6.36e-43

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 159.74  E-value: 6.36e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  262 VMDYPRPIMPNMVFIGGI--NCANGKPLSQEFEAYINASGEhGIVVFSLGSMVseipEKKAMA------IADALGKIPQT 333
Cdd:PHA03392 256 VFDNNRPVPPSVQYLGGLhlHKKPPQPLDDYLEEFLNNSTN-GVVYVSFGSSI----DTNDMDneflqmLLRTFKKLPYN 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  334 VLWRYTGT-RPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGV 412
Cdd:PHA03392 331 VLWKYDGEvEAINLPANVLTQKWFPQRAVLKHKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGR 410

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  413 TLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKG-APHLRPAAHDLTWYQYhsld 491
Cdd:PHA03392 411 ALDTVTVSAAQLVLAIVDVIENPKYRKNLKELRHLIRHQPMTPLHKAIWYTEHVIRNKHgNTSLKTKAANVSYSDY---- 486

                        250
                 ....*....|....*..
gi 46249404  492 VIGFLLAVVLTVAFITF 508
Cdd:PHA03392 487 FMSYILVPLVTFTVMNH 503
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
263-445 3.38e-30

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 118.81  E-value: 3.38e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404 263 MDYPRP-IMPNMVFIGGINCANGKPLSqefeAYINASGEHGIVVFSLGSMVSEiPEKKAMAIADALGKIPQTVLWRYTGT 341
Cdd:COG1819  85 LEYPRPpDPANVRFVGPLLPDGPAELP----PWLEEDAGRPLVYVTLGTSAND-RADLLRAVLEALADLGVRVVVTTGGL 159

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404 342 RPSNLAN---NTILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLE 418
Cdd:COG1819 160 DPAELGPlpdNVRVVDYVPQDALLPR--ADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRR 237

                       170       180
                ....*....|....*....|....*..
gi 46249404 419 MTSEDLENALKAVINDKSYKENIMRLS 445
Cdd:COG1819 238 LTAEALRAALRRLLADPSYRERAARLA 264
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 135-444 1.73e-20

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 93.60  E-value: 1.73e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   135 EALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVfflRNIPCDLDFKGTQCPNPSsyiprlLTTNSdhmtfLQRVKNM 214
Cdd:TIGR01426  82 PQLEEAYKGDRPDLIVYDIASWTGRLLARKWDVPVI---SSFPTFAANEEFEEMVSP------AGEGS-----AEEGAIA 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   215 LYPLAlsylchavsaPYASLASELFQREvsvvDLVSHASVWLF--RGDFVMDY-PRPIMPNMVFIGGINCANGKPL---S 288
Cdd:TIGR01426 148 ERGLA----------EYVARLSALLEEH----GITTPPVEFLAapRRDLNLVYtPKAFQPAGETFDDSFTFVGPCIgdrK 213

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   289 QEFEAYINASGeHGIVVFSLGSMVSEIPEKKAMAIaDALGKIP-QTVLWRYTGTRPSNLAN---NTILVKWLPQNDLLGH 364
Cdd:TIGR01426 214 EDGSWERPGDG-RPVVLISLGTVFNNQPSFYRTCV-EAFRDLDwHVVLSVGRGVDPADLGElppNVEVRQWVPQLEILKK 291

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   365 pmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRL 444
Cdd:TIGR01426 292 --ADAFITHGGMNSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLREAVLAVLSDPRYAERLRKM 369
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
29-525 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 866.72  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404    29 GKVLVVPTDGSHWLSMREALRDLHARGHQVVVLTLEVNMYIK--EENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHL 106
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGpgKPSNLKFETYPTSATKEELENPFPKRQMQWFEEASF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   107 LmKFSRRMAIMNNMSLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDLDFKGT- 185
Cdd:pfam00201  81 G-TVWSYFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSg 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   186 QCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQREVSVVDLVSHASVWLFRGDFVMDY 265
Cdd:pfam00201 160 GLPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLGRPVTLPELMSKASVWLIRSYWDLEF 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   266 PRPIMPNMVFIGGINCANGKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSN 345
Cdd:pfam00201 240 PRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPST 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   346 LANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLE 425
Cdd:pfam00201 320 LGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLL 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   426 NALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAF 505
Cdd:pfam00201 400 NALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAF 479

                         490       500
                  ....*....|....*....|
gi 46249404   506 ITFKCCAYGYRKCLGKKGRV 525
Cdd:pfam00201 480 ITFKCCLFGYRKFVGKKKRV 499
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 30-447 2.41e-74

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 241.30  E-value: 2.41e-74
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  30 KVLVVPTDG-SHWLSMREALRDLHARGHQVVVLTLEVNMyIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLM 108
Cdd:cd03784   2 RILFVPFPGqGHVNPMLPLAKALAARGHEVTVATPPFNF-ADLVEAAGLTFVPVGDDPDELELDSETNLGPDSLLELLRR 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404 109 KFSRRMAIMnnmsliihRSCVELLhnealirhLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDLDFkgtqCP 188
Cdd:cd03784  81 LLKAADELL--------DDLLAAL--------RSSWKPDLVIADPFAYAGPLVAEELGIPSVRLFTGPATLLSA----YL 140

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404 189 NPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLaselfqREVSVVDLVSHASVWLfrgdfvmdYPRP 268
Cdd:cd03784 141 HPFGVLNLLLSSLLEPELFLDPLLEVLDRLRERLGLPPFSLVLLLL------RLVPPLYVIGPTFPSL--------PPDR 206

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404 269 IMPNMVFIGGINCANGKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPS---N 345
Cdd:cd03784 207 PRLPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVGPDPLGgleR 286

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404 346 LANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLE 425
Cdd:cd03784 287 LPDNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEELA 366

                       410       420
                ....*....|....*....|..
gi 46249404 426 NALKAVINDKSYKENIMRLSSL 447
Cdd:cd03784 367 KAVREVLEDESYRRAAELLAEL 388
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 262-508 6.36e-43

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 159.74  E-value: 6.36e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  262 VMDYPRPIMPNMVFIGGI--NCANGKPLSQEFEAYINASGEhGIVVFSLGSMVseipEKKAMA------IADALGKIPQT 333
Cdd:PHA03392 256 VFDNNRPVPPSVQYLGGLhlHKKPPQPLDDYLEEFLNNSTN-GVVYVSFGSSI----DTNDMDneflqmLLRTFKKLPYN 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  334 VLWRYTGT-RPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGV 412
Cdd:PHA03392 331 VLWKYDGEvEAINLPANVLTQKWFPQRAVLKHKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGR 410

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  413 TLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKG-APHLRPAAHDLTWYQYhsld 491
Cdd:PHA03392 411 ALDTVTVSAAQLVLAIVDVIENPKYRKNLKELRHLIRHQPMTPLHKAIWYTEHVIRNKHgNTSLKTKAANVSYSDY---- 486

                        250
                 ....*....|....*..
gi 46249404  492 VIGFLLAVVLTVAFITF 508
Cdd:PHA03392 487 FMSYILVPLVTFTVMNH 503
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
263-445 3.38e-30

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 118.81  E-value: 3.38e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404 263 MDYPRP-IMPNMVFIGGINCANGKPLSqefeAYINASGEHGIVVFSLGSMVSEiPEKKAMAIADALGKIPQTVLWRYTGT 341
Cdd:COG1819  85 LEYPRPpDPANVRFVGPLLPDGPAELP----PWLEEDAGRPLVYVTLGTSAND-RADLLRAVLEALADLGVRVVVTTGGL 159

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404 342 RPSNLAN---NTILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLE 418
Cdd:COG1819 160 DPAELGPlpdNVRVVDYVPQDALLPR--ADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRR 237

                       170       180
                ....*....|....*....|....*..
gi 46249404 419 MTSEDLENALKAVINDKSYKENIMRLS 445
Cdd:COG1819 238 LTAEALRAALRRLLADPSYRERAARLA 264
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 135-444 1.73e-20

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 93.60  E-value: 1.73e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   135 EALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVfflRNIPCDLDFKGTQCPNPSsyiprlLTTNSdhmtfLQRVKNM 214
Cdd:TIGR01426  82 PQLEEAYKGDRPDLIVYDIASWTGRLLARKWDVPVI---SSFPTFAANEEFEEMVSP------AGEGS-----AEEGAIA 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   215 LYPLAlsylchavsaPYASLASELFQREvsvvDLVSHASVWLF--RGDFVMDY-PRPIMPNMVFIGGINCANGKPL---S 288
Cdd:TIGR01426 148 ERGLA----------EYVARLSALLEEH----GITTPPVEFLAapRRDLNLVYtPKAFQPAGETFDDSFTFVGPCIgdrK 213

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   289 QEFEAYINASGeHGIVVFSLGSMVSEIPEKKAMAIaDALGKIP-QTVLWRYTGTRPSNLAN---NTILVKWLPQNDLLGH 364
Cdd:TIGR01426 214 EDGSWERPGDG-RPVVLISLGTVFNNQPSFYRTCV-EAFRDLDwHVVLSVGRGVDPADLGElppNVEVRQWVPQLEILKK 291

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   365 pmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRL 444
Cdd:TIGR01426 292 --ADAFITHGGMNSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLREAVLAVLSDPRYAERLRKM 369
PLN02152 PLN02152
indole-3-acetate beta-glucosyltransferase
 268-436 5.60e-13

indole-3-acetate beta-glucosyltransferase


Pssm-ID: 177813 [Multi-domain]  Cd Length: 455  Bit Score: 70.85  E-value: 5.60e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  268 PIMPNMVFIGGincANGKPLSQE-----FEAYINASGEHGIVVFSLGSMVsEIPEKKAMAIADAL--GKIP--------- 331
Cdd:PLN02152 226 PLLPAEIFTGS---ESGKDLSVRdqsssYTLWLDSKTESSVIYVSFGTMV-ELSKKQIEELARALieGKRPflwvitdkl 301

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  332 ----------QTVLWRYTGTRpSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDN 401
Cdd:PLN02152 302 nreakiegeeETEIEKIAGFR-HELEEVGMIVSWCSQIEVLRHRAVGCFVTHCGWSSSLESLVLGVPVVAFPMWSDQPAN 380

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 46249404  402 AKRME---TKGAGVTLNVLEMTSE-DLENALKAVINDKS 436
Cdd:PLN02152 381 AKLLEeiwKTGVRVRENSEGLVERgEIRRCLEAVMEEKS 419
PLN02410 PLN02410
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 294-406 1.66e-12

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 178032 [Multi-domain]  Cd Length: 451  Bit Score: 69.30  E-value: 1.66e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  294 YINASGEHGIVVFSLGSM-VSEIPEkkAMAIADALGKIPQTVLWRytgTRPSNLANNT-----------------ILVKW 355
Cdd:PLN02410 257 WLNKQKKNSVIFVSLGSLaLMEINE--VMETASGLDSSNQQFLWV---IRPGSVRGSEwieslpkefskiisgrgYIVKW 331

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 46249404  356 LPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRME 406
Cdd:PLN02410 332 APQKEVLSHPAVGGFWSHCGWNSTLESIGEGVPMICKPFSSDQKVNARYLE 382
PLN02210 PLN02210
UDP-glucosyl transferase
 146-431 1.28e-09

UDP-glucosyl transferase


Pssm-ID: 215127 [Multi-domain]  Cd Length: 456  Bit Score: 60.43  E-value: 1.28e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  146 FDVVLTDPFHLCaavlakylsIPAVFFLRNIPCDLDFKgTQCPNPSSYIPRLLTTNS--DHMTFLQRVKNMLYPLAL--- 220
Cdd:PLN02210 104 YSCIISSPFTPW---------VPAVAAAHNIPCAILWI-QACGAYSVYYRYYMKTNSfpDLEDLNQTVELPALPLLEvrd 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  221 --SYLCHAVSAPYASLASElFQREVSVVDLVSHASVWLFRGDFV--MDYPRPIMP--NMV--FIGGIN---CANGKPL-- 287
Cdd:PLN02210 174 lpSFMLPSGGAHFNNLMAE-FADCLRYVKWVLVNSFYELESEIIesMADLKPVIPigPLVspFLLGDDeeeTLDGKNLdm 252

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  288 --SQEF-EAYINASGEHGIVVFSLGSMVSEIpEKKAMAIADALGKIPQTVLWRytgTRPSNLANNT------------IL 352
Cdd:PLN02210 253 ckSDDCcMEWLDKQARSSVVYISFGSMLESL-ENQVETIAKALKNRGVPFLWV---IRPKEKAQNVqvlqemvkegqgVV 328

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  353 VKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNVL----EMTSEDLENA 427
Cdd:PLN02210 329 LEWSPQEKILSHMAISCFVTHCGWNSTIETVVAGVPVVAYPSWTDQPIDARLLvDVFGIGVRMRNDavdgELKVEEVERC 408


                 ....
gi 46249404  428 LKAV 431
Cdd:PLN02210 409 IEAV 412
PLN03015 PLN03015
UDP-glucosyl transferase
 257-422 3.46e-09

UDP-glucosyl transferase


Pssm-ID: 178589 [Multi-domain]  Cd Length: 470  Bit Score: 58.94  E-value: 3.46e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  257 FRGDfvMDYPRpIMPNMVF-IGGINCANG--KPLSQEFEaYINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKIPQT 333
Cdd:PLN03015 224 LRED--MELNR-VMKVPVYpIGPIVRTNVhvEKRNSIFE-WLDKQGERSVVYVCLGSG-GTLTFEQTVELAWGLELSGQR 298

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  334 VLW------RYTG-----------TRPSNLANNT-----ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVM 391
Cdd:PLN03015 299 FVWvlrrpaSYLGasssdddqvsaSLPEGFLDRTrgvglVVTQWAPQVEILSHRSIGGFLSHCGWSSVLESLTKGVPIVA 378

                        170       180       190
                 ....*....|....*....|....*....|.
gi 46249404  392 MPLFGDQMDNAKrMETKGAGVTLNVLEMTSE 422
Cdd:PLN03015 379 WPLYAEQWMNAT-LLTEEIGVAVRTSELPSE 408
PLN02555 PLN02555
limonoid glucosyltransferase
 352-443 4.13e-09

limonoid glucosyltransferase


Pssm-ID: 178170 [Multi-domain]  Cd Length: 480  Bit Score: 59.04  E-value: 4.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  352 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTL------NVLEMTSEDL 424
Cdd:PLN02555 341 IVQWCPQEKVLAHPSVACFVTHCGWNSTMEALSSGVPVVCFPQWGDQVTDAVYLvDVFKTGVRLcrgeaeNKLITREEVA 420

                         90       100
                 ....*....|....*....|.
gi 46249404  425 ENALKAVINDKS--YKENIMR 443
Cdd:PLN02555 421 ECLLEATVGEKAaeLKQNALK 441
PLN02173 PLN02173
UDP-glucosyl transferase family protein
 294-447 5.07e-09

UDP-glucosyl transferase family protein


Pssm-ID: 177830 [Multi-domain]  Cd Length: 449  Bit Score: 58.50  E-value: 5.07e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  294 YINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKIpqTVLWRYTGTRPSNL---------ANNTILVKWLPQNDLLGH 364
Cdd:PLN02173 257 WLDKRPQGSVVYIAFGSM-AKLSSEQMEEIASAISNF--SYLWVVRASEESKLppgfletvdKDKSLVLKWSPQLQVLSN 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  365 PMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRME-TKGAGVTLNVLEMTS----EDLENALKAVIN---DKS 436
Cdd:PLN02173 334 KAIGCFMTHCGWNSTMEGLSLGVPMVAMPQWTDQPMNAKYIQdVWKVGVRVKAEKESGiakrEEIEFSIKEVMEgekSKE 413

                        170
                 ....*....|.
gi 46249404  437 YKENIMRLSSL 447
Cdd:PLN02173 414 MKENAGKWRDL 424
PLN02534 PLN02534
UDP-glycosyltransferase
 351-416 1.45e-08

UDP-glycosyltransferase


Pssm-ID: 215293 [Multi-domain]  Cd Length: 491  Bit Score: 57.18  E-value: 1.45e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 46249404  351 ILVK-WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNV 416
Cdd:PLN02534 346 LLIKgWAPQVLILSHPAIGGFLTHCGWNSTIEGICSGVPMITWPLFAEQFLNEKLIvEVLRIGVRVGV 413
PLN00164 PLN00164
glucosyltransferase; Provisional
 354-402 1.83e-08

glucosyltransferase; Provisional


Pssm-ID: 215084 [Multi-domain]  Cd Length: 480  Bit Score: 56.99  E-value: 1.83e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 46249404  354 KWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 402
Cdd:PLN00164 345 TWAPQKEILAHAAVGGFVTHCGWNSVLESLWHGVPMAPWPLYAEQHLNA 393
PLN02992 PLN02992
coniferyl-alcohol glucosyltransferase
 355-402 2.48e-08

coniferyl-alcohol glucosyltransferase


Pssm-ID: 178572 [Multi-domain]  Cd Length: 481  Bit Score: 56.53  E-value: 2.48e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 46249404  355 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 402
Cdd:PLN02992 345 WAPQAEILAHQAVGGFLTHCGWSSTLESVVGGVPMIAWPLFAEQNMNA 392
PLN03004 PLN03004
UDP-glycosyltransferase
 294-446 4.42e-08

UDP-glycosyltransferase


Pssm-ID: 178581  Cd Length: 451  Bit Score: 55.47  E-value: 4.42e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  294 YINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKIPQTVLWryTGTRPSNLANNTILVK------------------- 354
Cdd:PLN03004 263 WLDSQPEKSVVFLCFGSL-GLFSKEQVIEIAVGLEKSGQRFLW--VVRNPPELEKTELDLKsllpegflsrtedkgmvvk 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  355 -WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNVLE---MTSEDLENALK 429
Cdd:PLN03004 340 sWAPQVPVLNHKAVGGFVTHCGWNSILEAVCAGVPMVAWPLYAEQRFNRVMIvDEIKIAISMNESEtgfVSSTEVEKRVQ 419

                        170
                 ....*....|....*..
gi 46249404  430 AVINDKSYKENIMRLSS 446
Cdd:PLN03004 420 EIIGECPVRERTMAMKN 436
PLN02167 PLN02167
UDP-glycosyltransferase family protein
 264-405 5.25e-08

UDP-glycosyltransferase family protein


Pssm-ID: 215112 [Multi-domain]  Cd Length: 475  Bit Score: 55.19  E-value: 5.25e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  264 DYPrPIMPnmvfIGGINCANGKP-----LSQ--EFEAYINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLW 336
Cdd:PLN02167 241 NYP-PVYP----VGPILSLKDRTspnldSSDrdRIMRWLDDQPESSVVFLCFGSLGS-LPAPQIKEIAQALELVGCRFLW 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  337 --RYTGTR--------PSNLANNT----ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 402
Cdd:PLN02167 315 siRTNPAEyaspyeplPEGFMDRVmgrgLVCGWAPQVEILAHKAIGGFVSHCGWNSVLESLWFGVPIATWPMYAEQQLNA 394


                 ...
gi 46249404  403 KRM 405
Cdd:PLN02167 395 FTM 397
PLN02448 PLN02448
UDP-glycosyltransferase family protein
 268-403 2.11e-07

UDP-glycosyltransferase family protein


Pssm-ID: 215247 [Multi-domain]  Cd Length: 459  Bit Score: 53.47  E-value: 2.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  268 PIMPNMVFIGGINCANGKPLSQEFEAYINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLW---RYTGTRPS 344
Cdd:PLN02448 241 PSIPYMELKDNSSSSNNEDNEPDYFQWLDSQPEGSVLYVSLGSFLS-VSSAQMDEIAAGLRDSGVRFLWvarGEASRLKE 319

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 46249404  345 NLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAK 403
Cdd:PLN02448 320 ICGDMGLVVPWCDQLKVLCHSSVGGFWTHCGWNSTLEAVFAGVPMLTFPLFWDQPLNSK 378
PLN02562 PLN02562
UDP-glycosyltransferase
 303-444 2.28e-07

UDP-glycosyltransferase


Pssm-ID: 215305  Cd Length: 448  Bit Score: 53.35  E-value: 2.28e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  303 IVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYT-----GTRPS---NLANNTILVKWLPQNDLLGHPMTRAFITHA 374
Cdd:PLN02562 275 VIYISFGSWVSPIGESNVRTLALALEASGRPFIWVLNpvwreGLPPGyveRVSKQGKVVSWAPQLEVLKHQAVGCYLTHC 354

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 46249404  375 GSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNvlEMTSEDLENALKAVINDKSYKENIMRL 444
Cdd:PLN02562 355 GWNSTMEAIQCQKRLLCYPVAGDQFVNCAYIvDVWKIGVRIS--GFGQKEVEEGLRKVMEDSGMGERLMKL 423
PLN02554 PLN02554
UDP-glycosyltransferase family protein
 352-445 5.89e-07

UDP-glycosyltransferase family protein


Pssm-ID: 215304  Cd Length: 481  Bit Score: 52.10  E-value: 5.89e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  352 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTL-----------NVLEM 419
Cdd:PLN02554 346 VIGWAPQVAVLAKPAIGGFVTHCGWNSILESLWFGVPMAAWPLYAEQKFNAFEMvEELGLAVEIrkywrgdllagEMETV 425

                         90       100
                 ....*....|....*....|....*..
gi 46249404  420 TSEDLENALKAVI-NDKSYKENIMRLS 445
Cdd:PLN02554 426 TAEEIERGIRCLMeQDSDVRKRVKEMS 452
PLN02863 PLN02863
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 351-402 5.95e-06

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 215465  Cd Length: 477  Bit Score: 48.71  E-value: 5.95e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 46249404  351 ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 402
Cdd:PLN02863 346 VIRGWAPQVAILSHRAVGAFLTHCGWNSVLEGLVAGVPMLAWPMAADQFVNA 397
PLN02207 PLN02207
UDP-glycosyltransferase
 290-405 6.23e-06

UDP-glycosyltransferase


Pssm-ID: 177857 [Multi-domain]  Cd Length: 468  Bit Score: 48.88  E-value: 6.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  290 EFEAYINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLWRYTGTRPSN-----------LANNTILVKWLPQ 358
Cdd:PLN02207 264 ELMKWLDDQPEASVVFLCFGSMGR-LRGPLVKEIAHGLELCQYRFLWSLRTEEVTNddllpegfldrVSGRGMICGWSPQ 342

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 46249404  359 NDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM 405
Cdd:PLN02207 343 VEILAHKAVGGFVSHCGWNSIVESLWFGVPIVTWPMYAEQQLNAFLM 389
PLN02208 PLN02208
glycosyltransferase family protein
 355-436 1.27e-05

glycosyltransferase family protein


Pssm-ID: 177858  Cd Length: 442  Bit Score: 47.70  E-value: 1.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  355 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMdNAKRMETKGAGVTLNVLE-----MTSEDLENALK 429
Cdd:PLN02208 318 WVQQPLILDHPSIGCFVNHCGPGTIWESLVSDCQMVLIPFLSDQV-LFTRLMTEEFEVSVEVSRektgwFSKESLSNAIK 396


                 ....*..
gi 46249404  430 AVINDKS 436
Cdd:PLN02208 397 SVMDKDS 403
PLN03007 PLN03007
UDP-glucosyltransferase family protein
 303-447 1.78e-05

UDP-glucosyltransferase family protein


Pssm-ID: 178584 [Multi-domain]  Cd Length: 482  Bit Score: 47.16  E-value: 1.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  303 IVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLW--RYTGTRPSN------------LANNTILVKWLPQNDLLGHPMTR 368
Cdd:PLN03007 287 VIYLSFGSVAS-FKNEQLFEIAAGLEGSGQNFIWvvRKNENQGEKeewlpegfeertKGKGLIIRGWAPQVLILDHQATG 365

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  369 AFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNVLEM--------TSEDLENALKAVINDKSYKE 439
Cdd:PLN03007 366 GFVTHCGWNSLLEGVAAGLPMVTWPVGAEQFYNEKLVtQVLRTGVSVGAKKLvkvkgdfiSREKVEKAVREVIVGEEAEE 445


                 ....*...
gi 46249404  440 NIMRLSSL 447
Cdd:PLN03007 446 RRLRAKKL 453
Glyco_tran_28_C pfam04101
Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes ...
 371-451 3.37e-05

Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.


Pssm-ID: 427711 [Multi-domain]  Cd Length: 166  Bit Score: 44.24  E-value: 3.37e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404   371 ITHAGSHGVYESICNGVPMVMMPL----FGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSS 446
Cdd:pfam04101  76 ISRAGAGTIAELLALGKPAILVPNpsaaRGHQDNNAKELVKAGAALVILQKELTPEKLIEALLKLLLNPLRLAEMAKASK 155


                  ....*
gi 46249404   447 LHKDR 451
Cdd:pfam04101 156 ASGFK 160
PLN00414 PLN00414
glycosyltransferase family protein
 283-466 4.98e-05

glycosyltransferase family protein


Pssm-ID: 177807 [Multi-domain]  Cd Length: 446  Bit Score: 45.78  E-value: 4.98e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  283 NGKPLSQEFEAYIN----------ASGEH-------------GIVVFSLGSMVSEIPEKKAMAIADALgkiPQTVLWRYT 339
Cdd:PLN00414 234 SGKPLEDRWNHWLNgfepgsvvfcAFGTQfffekdqfqefclGMELTGLPFLIAVMPPKGSSTVQEAL---PEGFEERVK 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  340 GtrpsnlaNNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMdNAKRMETKGAGVTLNVLE- 418
Cdd:PLN00414 311 G-------RGIVWEGWVEQPLILSHPSVGCFVNHCGFGSMWESLVSDCQIVFIPQLADQV-LITRLLTEELEVSVKVQRe 382

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 46249404  419 ----MTSEDLENALKAVINDKSYKENIMRLSSLH-KDRPVEPLDLAVFWVEFV 466
Cdd:PLN00414 383 dsgwFSKESLRDTVKSVMDKDSEIGNLVKRNHKKlKETLVSPGLLSGYADKFV 435
GT28_MurG cd03785
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4. ...
 371-445 8.43e-05

undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340818 [Multi-domain]  Cd Length: 350  Bit Score: 44.90  E-value: 8.43e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404 371 ITHAGSHGVYESICNGVPMVMMPLF----GDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVIND----KSYKENIM 442
Cdd:cd03785 257 ISRAGASTIAELTAAGKPAILIPYPyaadDHQEANARALEKAGAAIVIDQEELTPEVLAEAILDLLNDperlKKMAEAAK 336


                ...
gi 46249404 443 RLS 445
Cdd:cd03785 337 KLA 339
MurG COG0707
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope ...
 371-445 1.97e-04

UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440471 [Multi-domain]  Cd Length: 363  Bit Score: 43.58  E-value: 1.97e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404 371 ITHAGSHGVYESICNGVPMVMMPL-F---GDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVIND----KSYKENIM 442
Cdd:COG0707 263 ISRAGASTVAELAALGKPAILVPLpHaadDHQTKNARALVEAGAAVLIPQSELTPEKLAEALEELLEDperlAKMAEAAR 342


                ...
gi 46249404 443 RLS 445
Cdd:COG0707 343 ALA 345
PLN02764 PLN02764
glycosyltransferase family protein
 355-443 2.51e-04

glycosyltransferase family protein


Pssm-ID: 178364  Cd Length: 453  Bit Score: 43.51  E-value: 2.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404  355 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKgAGVTLNVLE-----MTSEDLENALK 429
Cdd:PLN02764 324 WVQQPLILSHPSVGCFVSHCGFGSMWESLLSDCQIVLVPQLGDQVLNTRLLSDE-LKVSVEVAReetgwFSKESLRDAIN 402

                         90
                 ....*....|....
gi 46249404  430 AVINDKSYKENIMR 443
Cdd:PLN02764 403 SVMKRDSEIGNLVK 416
PLN02670 PLN02670
transferase, transferring glycosyl groups
 351-412 2.67e-04

transferase, transferring glycosyl groups


Pssm-ID: 178275 [Multi-domain]  Cd Length: 472  Bit Score: 43.74  E-value: 2.67e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 46249404  351 ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGV 412
Cdd:PLN02670 342 IHVGWVPQVKILSHESVGGFLTHCGWNSVVEGLGFGRVLILFPVLNEQGLNTRLLHGKKLGL 403
murG PRK00726
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
 371-443 1.59e-03

undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional


Pssm-ID: 234825 [Multi-domain]  Cd Length: 357  Bit Score: 40.88  E-value: 1.59e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 46249404  371 ITHAGSHGVYESICNGVPMVMMPL----FGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMR 443
Cdd:PRK00726 257 ICRAGASTVAELAAAGLPAILVPLphaaDDHQTANARALVDAGAALLIPQSDLTPEKLAEKLLELLSDPERLEAMAE 333
GT28_Beta-DGS-like cd17507
beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol ...
 359-444 1.82e-03

beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol synthase (processive diacylglycerol beta-glucosyltransferase EC 2.4.1.315) is involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. This family of glycosyltransferases also contains plant major galactolipid synthase (chloroplastic monogalactosyldiacylglycerol synthase 1 EC 2.4.1.46). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340861 [Multi-domain]  Cd Length: 364  Bit Score: 40.76  E-value: 1.82e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46249404 359 NDLLGhpMTRAFITHAGSHGVYESICNGVPMVM-MPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSY 437
Cdd:cd17507 262 NELMA--ASDLVITKPGGLTISEALARGLPVIIyDPIPGQEEENADFLENNGAGIIARDPEELLEIVARLIDPPSLLRMM 339


                ....*..
gi 46249404 438 KENIMRL 444
Cdd:cd17507 340 SEAAKEL 346
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH