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Conserved domains on  [gi|32171180|ref|NP_065158|]
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small integral membrane protein 8 isoform 1 [Homo sapiens]

Protein Classification

small integral membrane protein 8( domain architecture ID 10633090)

small integral membrane protein 8 (SMIM8) is a DUF4500 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4500 pfam14937
Domain of unknown function (DUF4500); This family is found in eukaryotes. The function of this ...
 15-96 7.04e-49

Domain of unknown function (DUF4500); This family is found in eukaryotes. The function of this protein remains unknown. The gene which encodes for this protein is named chromosome 6 open reading frame 162 (C6orf162) and is found between the chromosomal positions 6q15-q16.1. It is thought that this protein may be an important part of membrane function.


:

Pssm-ID: 434330  Cd Length: 81  Bit Score: 149.38  E-value: 7.04e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32171180   15 PKEKEFQSPGLRGVRTTTLFRAVNPELFIKPNKPVMAFGLVTLSLCVAYIGYLHAIQENKKdLYEAIDSEGHSYMRRKTS 94
Cdd:pfam14937  1 PKKKAYPGDGLRSVKTTTLFRAVNFELYVKPNKVIMALGLVAITGCVGYIAYMRAKYENLG-YYEAVDSDGTEYMRKKKS 79


                 ..
gi 32171180   95 KW 96
Cdd:pfam14937 80 KW 81
 
Name Accession Description Interval E-value
DUF4500 pfam14937
Domain of unknown function (DUF4500); This family is found in eukaryotes. The function of this ...
 15-96 7.04e-49

Domain of unknown function (DUF4500); This family is found in eukaryotes. The function of this protein remains unknown. The gene which encodes for this protein is named chromosome 6 open reading frame 162 (C6orf162) and is found between the chromosomal positions 6q15-q16.1. It is thought that this protein may be an important part of membrane function.


Pssm-ID: 434330  Cd Length: 81  Bit Score: 149.38  E-value: 7.04e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32171180   15 PKEKEFQSPGLRGVRTTTLFRAVNPELFIKPNKPVMAFGLVTLSLCVAYIGYLHAIQENKKdLYEAIDSEGHSYMRRKTS 94
Cdd:pfam14937  1 PKKKAYPGDGLRSVKTTTLFRAVNFELYVKPNKVIMALGLVAITGCVGYIAYMRAKYENLG-YYEAVDSDGTEYMRKKKS 79


                 ..
gi 32171180   95 KW 96
Cdd:pfam14937 80 KW 81
 
Name Accession Description Interval E-value
DUF4500 pfam14937
Domain of unknown function (DUF4500); This family is found in eukaryotes. The function of this ...
 15-96 7.04e-49

Domain of unknown function (DUF4500); This family is found in eukaryotes. The function of this protein remains unknown. The gene which encodes for this protein is named chromosome 6 open reading frame 162 (C6orf162) and is found between the chromosomal positions 6q15-q16.1. It is thought that this protein may be an important part of membrane function.


Pssm-ID: 434330  Cd Length: 81  Bit Score: 149.38  E-value: 7.04e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32171180   15 PKEKEFQSPGLRGVRTTTLFRAVNPELFIKPNKPVMAFGLVTLSLCVAYIGYLHAIQENKKdLYEAIDSEGHSYMRRKTS 94
Cdd:pfam14937  1 PKKKAYPGDGLRSVKTTTLFRAVNFELYVKPNKVIMALGLVAITGCVGYIAYMRAKYENLG-YYEAVDSDGTEYMRKKKS 79


                 ..
gi 32171180   95 KW 96
Cdd:pfam14937 80 KW 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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