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Conserved domains on  [gi|10190722|ref|NP_065729|]
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leucine-rich repeat and transmembrane domain-containing protein 1 isoform 1 precursor [Homo sapiens]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
34-180 9.92e-13

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 68.42  E-value: 9.92e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722  34 VDCSQQGLAEIPSHLPPQT--RTLHLQDNQIHHLPAfafrsvpwlmtlnlsnnslsnlapgAFHGLQHLQVLNLTQNSLL 111
Cdd:COG4886 118 LDLSGNQLTDLPEELANLTnlKELDLSNNQLTDLPE-------------------------PLGNLTNLKSLDLSNNQLT 172

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 10190722 112 SLESRLFhSLPQLRELDLSSNNISHLPTSLGEtWENLTILAVQQNQLQQLDRAlLESMPSVRLLLLKDN 180
Cdd:COG4886 173 DLPEELG-NLTNLKELDLSNNQITDLPEPLGN-LTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNN 238
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
34-180 9.92e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 68.42  E-value: 9.92e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722  34 VDCSQQGLAEIPSHLPPQT--RTLHLQDNQIHHLPAfafrsvpwlmtlnlsnnslsnlapgAFHGLQHLQVLNLTQNSLL 111
Cdd:COG4886 118 LDLSGNQLTDLPEELANLTnlKELDLSNNQLTDLPE-------------------------PLGNLTNLKSLDLSNNQLT 172

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 10190722 112 SLESRLFhSLPQLRELDLSSNNISHLPTSLGEtWENLTILAVQQNQLQQLDRAlLESMPSVRLLLLKDN 180
Cdd:COG4886 173 DLPEELG-NLTNLKELDLSNNQITDLPEPLGN-LTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNN 238
LRR_8 pfam13855
Leucine rich repeat;
50-134 1.47e-12

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 61.77  E-value: 1.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722    50 PQTRTLHLQDNQIHHLPafafrsvpwlmtlnlsnnslsnlaPGAFHGLQHLQVLNLTQNSLLSLESRLFHSLPQLRELDL 129
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLD------------------------DGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDL 56


                  ....*
gi 10190722   130 SSNNI 134
Cdd:pfam13855  57 SGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
29-173 3.03e-07

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 52.01  E-value: 3.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722   29 SSTNFVDCSQQGLAEIPSHLPPQTRTLHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPgafhglQHLQVLNLTQN 108
Cdd:PRK15370 262 SALQSLDLFHNKISCLPENLPEELRYLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALPETLP------PGLKTLEAGEN 335

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722  109 SLLSLESRLfhsLPQLRELDLSSNNISHLPTSLGETWENLTI---------------LAVQQNQLQQLDRaLLESMPSVR 173
Cdd:PRK15370 336 ALTSLPASL---PPELQVLDVSKNQITVLPETLPPTITTLDVsrnaltnlpenlpaaLQIMQASRNNLVR-LPESLPHFR 411
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 100-156 8.54e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 43.24  E-value: 8.54e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 10190722 100 LQVLNLTQNSLLSLESrlFHSLPQLRELDLSSNNISHLP--TSLGETWENLTILAVQQN 156
Cdd:cd21340 122 LRVLNISGNNIDSLEP--LAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGN 178
LRR smart00370
Leucine-rich repeats, outliers;
121-138 2.92e-03

Leucine-rich repeats, outliers;


Pssm-ID: 197688 [Multi-domain]  Cd Length: 24  Bit Score: 34.63  E-value: 2.92e-03
                           10
                   ....*....|....*...
gi 10190722    121 LPQLRELDLSSNNISHLP 138
Cdd:smart00370   1 LPNLRELDLSNNQLSSLP 18
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
34-180 9.92e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 68.42  E-value: 9.92e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722  34 VDCSQQGLAEIPSHLPPQT--RTLHLQDNQIHHLPAfafrsvpwlmtlnlsnnslsnlapgAFHGLQHLQVLNLTQNSLL 111
Cdd:COG4886 118 LDLSGNQLTDLPEELANLTnlKELDLSNNQLTDLPE-------------------------PLGNLTNLKSLDLSNNQLT 172

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 10190722 112 SLESRLFhSLPQLRELDLSSNNISHLPTSLGEtWENLTILAVQQNQLQQLDRAlLESMPSVRLLLLKDN 180
Cdd:COG4886 173 DLPEELG-NLTNLKELDLSNNQITDLPEPLGN-LTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNN 238
LRR_8 pfam13855
Leucine rich repeat;
50-134 1.47e-12

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 61.77  E-value: 1.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722    50 PQTRTLHLQDNQIHHLPafafrsvpwlmtlnlsnnslsnlaPGAFHGLQHLQVLNLTQNSLLSLESRLFHSLPQLRELDL 129
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLD------------------------DGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDL 56


                  ....*
gi 10190722   130 SSNNI 134
Cdd:pfam13855  57 SGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
35-193 7.02e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 59.95  E-value: 7.02e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722  35 DCSQQGLAEIPSHL--PPQTRTLHLQDNQIHHLPAfafrsvpwlmtlnlsnnslsnlapgAFHGLQHLQVLNLTQNSLLS 112
Cdd:COG4886 188 DLSNNQITDLPEPLgnLTNLEELDLSGNQLTDLPE-------------------------PLANLTNLETLDLSNNQLTD 242

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722 113 LESrlFHSLPQLRELDLSSNNISHLPTSLGetWENLTILAVQQNQLQQLDRALLESMPSVRLLLLKDNLWKCNCHLLGLK 192
Cdd:COG4886 243 LPE--LGNLTNLEELDLSNNQLTDLPPLAN--LTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLL 318


                .
gi 10190722 193 L 193
Cdd:COG4886 319 L 319
LRR_8 pfam13855
Leucine rich repeat;
122-181 7.31e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 48.67  E-value: 7.31e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722   122 PQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRALLESMPSVRLLLLKDNL 181
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNR 60
LRR_8 pfam13855
Leucine rich repeat;
98-158 8.07e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 48.29  E-value: 8.07e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 10190722    98 QHLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQL 158
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
29-173 3.03e-07

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 52.01  E-value: 3.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722   29 SSTNFVDCSQQGLAEIPSHLPPQTRTLHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPgafhglQHLQVLNLTQN 108
Cdd:PRK15370 262 SALQSLDLFHNKISCLPENLPEELRYLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALPETLP------PGLKTLEAGEN 335

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722  109 SLLSLESRLfhsLPQLRELDLSSNNISHLPTSLGETWENLTI---------------LAVQQNQLQQLDRaLLESMPSVR 173
Cdd:PRK15370 336 ALTSLPASL---PPELQVLDVSKNQITVLPETLPPTITTLDVsrnaltnlpenlpaaLQIMQASRNNLVR-LPESLPHFR 411
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
94-180 9.42e-07

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 50.32  E-value: 9.42e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722  94 FHGLQHLQVLNLTQNSLLSlesrlfhSLPQLRELDLSSNNISHLPTSLGEtWENLTILAVQQNQLQQLDRAlLESMPSVR 173
Cdd:COG4886  92 LGDLTNLTELDLSGNEELS-------NLTNLESLDLSGNQLTDLPEELAN-LTNLKELDLSNNQLTDLPEP-LGNLTNLK 162


                ....*..
gi 10190722 174 LLLLKDN 180
Cdd:COG4886 163 SLDLSNN 169
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
40-171 1.93e-06

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 49.70  E-value: 1.93e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722   40 GLAEIPSHLPPQTRTLHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAfhglqhLQVLNLTQNSLLSLESRLFH 119
Cdd:PRK15370 189 GLTTIPACIPEQITTLILDNNELKSLPENLQGNIKTLYANSNQLTSIPATLPDT------IQEMELSINRITELPERLPS 262

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 10190722  120 SlpqLRELDLSSNNISHLPTSLGetwENLTILAVQQNQLqqldRALLESMPS 171
Cdd:PRK15370 263 A---LQSLDLFHNKISCLPENLP---EELRYLSVYDNSI----RTLPAHLPS 304
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 100-156 8.54e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 43.24  E-value: 8.54e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 10190722 100 LQVLNLTQNSLLSLESrlFHSLPQLRELDLSSNNISHLP--TSLGETWENLTILAVQQN 156
Cdd:cd21340 122 LRVLNISGNNIDSLEP--LAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGN 178
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 36-180 2.42e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 41.70  E-value: 2.42e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722  36 CSQQGLAEIPS-HLPPQTRTLHLQDNQIHHLPAFAFrsvpwlmtlnlsnnslsnlapgafhgLQHLQVLNLTQNSLLSLE 114
Cdd:cd21340   9 LNDKNITKIDNlSLCKNLKVLYLYDNKITKIENLEF--------------------------LTNLTHLYLQNNQIEKIE 62

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722 115 SrlFHSLPQLRELDLSSNNISHL----------------------------PTSLGETWENLTILAVQQNQLQQLDraLL 166
Cdd:cd21340  63 N--LENLVNLKKLYLGGNRISVVeglenltnleelhienqrlppgekltfdPRSLAALSNSLRVLNISGNNIDSLE--PL 138

                       170
                ....*....|....
gi 10190722 167 ESMPSVRLLLLKDN 180
Cdd:cd21340 139 APLRNLEQLDASNN 152
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 98-133 3.31e-04

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 38.00  E-value: 3.31e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 10190722    98 QHLQVLNLTQNSLLSLEsrLFHSLPQLRELDLSSNN 133
Cdd:pfam12799   1 PNLEVLDLSNNQITDIP--PLAKLPNLETLDLSGNN 34
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
41-205 4.09e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 41.84  E-value: 4.09e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722  41 LAEIPSHLP--PQTRTLHLQDNQIHHLPAFAfrsvpwlmtlnlsnnslsnlapgafhGLQHLQVLNLTQNSLLSLESRLf 118
Cdd:COG4886 217 LTDLPEPLAnlTNLETLDLSNNQLTDLPELG--------------------------NLTNLEELDLSNNQLTDLPPLA- 269

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722 119 hSLPQLRELDLSSNNISHLptSLGETWENLTILAVQQNQLQQLDRALLESMPSVRLLLLKDNLWKCNCHLLGLKLWLEKF 198
Cdd:COG4886 270 -NLTNLKTLDLSNNQLTDL--KLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSL 346


                ....*..
gi 10190722 199 VYKGGLT 205
Cdd:COG4886 347 LALLTLL 353
PLN03150 PLN03150
hypothetical protein; Provisional
 97-158 5.76e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 41.73  E-value: 5.76e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 10190722   97 LQHLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSNNIS-HLPTSLGETwENLTILAVQQNQL 158
Cdd:PLN03150 441 LRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQL-TSLRILNLNGNSL 502
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 94-138 9.50e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 40.15  E-value: 9.50e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*..
gi 10190722  94 FHGLQHLQVLNLTQNSLLSLE--SRLFHSLPQLRELDLSSNNISHLP 138
Cdd:cd21340 138 LAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPVCKKP 184
LRR smart00370
Leucine-rich repeats, outliers;
121-138 2.92e-03

Leucine-rich repeats, outliers;


Pssm-ID: 197688 [Multi-domain]  Cd Length: 24  Bit Score: 34.63  E-value: 2.92e-03
                           10
                   ....*....|....*...
gi 10190722    121 LPQLRELDLSSNNISHLP 138
Cdd:smart00370   1 LPNLRELDLSNNQLSSLP 18
LRR_TYP smart00369
Leucine-rich repeats, typical (most populated) subfamily;
121-138 2.92e-03

Leucine-rich repeats, typical (most populated) subfamily;


Pssm-ID: 197687 [Multi-domain]  Cd Length: 24  Bit Score: 34.63  E-value: 2.92e-03
                           10
                   ....*....|....*...
gi 10190722    121 LPQLRELDLSSNNISHLP 138
Cdd:smart00369   1 LPNLRELDLSNNQLSSLP 18
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
27-191 3.73e-03

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 39.38  E-value: 3.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722   27 CQSSTNFV-DCSQQGLAEIPSHLPPQTRTLHLQDNQIHHLPAFAfrsvpwlmtlnlsnnslsnlapgafhglQHLQVLNL 105
Cdd:PRK15387 198 CLNNGNAVlNVGESGLTTLPDCLPAHITTLVIPDNNLTSLPALP----------------------------PELRTLEV 249

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722  106 TQNSLLSLESRlfhsLPQLRELDLSSNNISH---LPTSLGETW---ENLTILAVQQNQLQQLDRA--LLESMPSVRLLLL 177
Cdd:PRK15387 250 SGNQLTSLPVL----PPGLLELSIFSNPLTHlpaLPSGLCKLWifgNQLTSLPVLPPGLQELSVSdnQLASLPALPSELC 325

                        170
                 ....*....|....
gi 10190722  178 KdnLWKCNCHLLGL 191
Cdd:PRK15387 326 K--LWAYNNQLTSL 337
LRR_9 pfam14580
Leucine-rich repeat;
97-180 6.16e-03

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 37.05  E-value: 6.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722    97 LQHLQVLNLTQNSLLSLESrlFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQL-DRALLESMPSVRLL 175
Cdd:pfam14580  41 LDQFDTIDFSDNEIRKLDG--FPLLRRLKTLLLNNNRICRIGEGLGEALPNLTELILTNNNLQELgDLDPLASLKKLTFL 118


                  ....*
gi 10190722   176 LLKDN 180
Cdd:pfam14580 119 SLLRN 123
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 94-180 9.08e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 37.91  E-value: 9.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10190722   94 FHGLQHLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSNNIS-HLPTSLgETWENLTILAVQQNQLQQLDRALLESMPSV 172
Cdd:PLN00113 471 SFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSgEIPDEL-SSCKKLVSLDLSHNQLSGQIPASFSEMPVL 549


                 ....*...
gi 10190722  173 RLLLLKDN 180
Cdd:PLN00113 550 SQLDLSQN 557
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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