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Conserved domains on  [gi|1488192508|ref|NP_065882|]
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myocardin-related transcription factor A isoform 5 [Homo sapiens]

Protein Classification

SAP domain-containing protein( domain architecture ID 10653801)

SAP (SAF-A/B, Acinus and PIAS) domain-containing protein may bind DNA or RNA and act as a transcriptional regulator

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SAP pfam02037
SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...
 447-480 1.14e-10

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.


:

Pssm-ID: 460424 [Multi-domain]  Cd Length: 35  Bit Score: 57.03  E-value: 1.14e-10
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1488192508  447 LDDMKVAELKQELKLRSLPVSGTKTELIERLRAY 480
Cdd:pfam02037    1 LSKLTVAELKEELRKRGLPTSGKKAELIERLQEY 34
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
124-149 7.94e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 43.23  E-value: 7.94e-06
                            10        20
                    ....*....|....*....|....*.
gi 1488192508   124 DYLKRKIRSRPERSELVRMHILEETS 149
Cdd:smart00707    1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
168-193 9.57e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 43.23  E-value: 9.57e-06
                            10        20
                    ....*....|....*....|....*.
gi 1488192508   168 DDLNEKIAQRPGPMELVEKNILPVES 193
Cdd:smart00707    1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
81-105 9.48e-05

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 40.15  E-value: 9.48e-05
                            10        20
                    ....*....|....*....|....*
gi 1488192508    81 VLQLKLQQRRTREELVSQGIMPPLK 105
Cdd:smart00707    2 VLNRKLSQRPTREELEERNILKELS 26
 
Name Accession Description Interval E-value
SAP pfam02037
SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...
 447-480 1.14e-10

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.


Pssm-ID: 460424 [Multi-domain]  Cd Length: 35  Bit Score: 57.03  E-value: 1.14e-10
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1488192508  447 LDDMKVAELKQELKLRSLPVSGTKTELIERLRAY 480
Cdd:pfam02037    1 LSKLTVAELKEELRKRGLPTSGKKAELIERLQEY 34
SAP smart00513
Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;
447-480 2.52e-09

Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;


Pssm-ID: 128789 [Multi-domain]  Cd Length: 35  Bit Score: 53.26  E-value: 2.52e-09
                            10        20        30
                    ....*....|....*....|....*....|....
gi 1488192508   447 LDDMKVAELKQELKLRSLPVSGTKTELIERLRAY 480
Cdd:smart00513    1 LAKLKVSELKDELKKRGLSTSGTKAELVDRLLEA 34
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
124-149 7.94e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 43.23  E-value: 7.94e-06
                            10        20
                    ....*....|....*....|....*.
gi 1488192508   124 DYLKRKIRSRPERSELVRMHILEETS 149
Cdd:smart00707    1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
168-193 9.57e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 43.23  E-value: 9.57e-06
                            10        20
                    ....*....|....*....|....*.
gi 1488192508   168 DDLNEKIAQRPGPMELVEKNILPVES 193
Cdd:smart00707    1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 169-190 6.04e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 40.72  E-value: 6.04e-05
                           10        20
                   ....*....|....*....|..
gi 1488192508  169 DLNEKIAQRPGPMELVEKNILP 190
Cdd:pfam02755    1 SLERKLSHRPTREELVERNILP 22
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
81-105 9.48e-05

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 40.15  E-value: 9.48e-05
                            10        20
                    ....*....|....*....|....*
gi 1488192508    81 VLQLKLQQRRTREELVSQGIMPPLK 105
Cdd:smart00707    2 VLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 126-148 4.42e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 38.41  E-value: 4.42e-04
                           10        20
                   ....*....|....*....|...
gi 1488192508  126 LKRKIRSRPERSELVRMHILEET 148
Cdd:pfam02755    2 LERKLSHRPTREELVERNILPED 24
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 82-103 9.69e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 37.25  E-value: 9.69e-04
                           10        20
                   ....*....|....*....|..
gi 1488192508   82 LQLKLQQRRTREELVSQGIMPP 103
Cdd:pfam02755    2 LERKLSHRPTREELVERNILPE 23
 
Name Accession Description Interval E-value
SAP pfam02037
SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...
 447-480 1.14e-10

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.


Pssm-ID: 460424 [Multi-domain]  Cd Length: 35  Bit Score: 57.03  E-value: 1.14e-10
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1488192508  447 LDDMKVAELKQELKLRSLPVSGTKTELIERLRAY 480
Cdd:pfam02037    1 LSKLTVAELKEELRKRGLPTSGKKAELIERLQEY 34
SAP smart00513
Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;
447-480 2.52e-09

Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;


Pssm-ID: 128789 [Multi-domain]  Cd Length: 35  Bit Score: 53.26  E-value: 2.52e-09
                            10        20        30
                    ....*....|....*....|....*....|....
gi 1488192508   447 LDDMKVAELKQELKLRSLPVSGTKTELIERLRAY 480
Cdd:smart00513    1 LAKLKVSELKDELKKRGLSTSGTKAELVDRLLEA 34
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
124-149 7.94e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 43.23  E-value: 7.94e-06
                            10        20
                    ....*....|....*....|....*.
gi 1488192508   124 DYLKRKIRSRPERSELVRMHILEETS 149
Cdd:smart00707    1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
168-193 9.57e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 43.23  E-value: 9.57e-06
                            10        20
                    ....*....|....*....|....*.
gi 1488192508   168 DDLNEKIAQRPGPMELVEKNILPVES 193
Cdd:smart00707    1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 169-190 6.04e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 40.72  E-value: 6.04e-05
                           10        20
                   ....*....|....*....|..
gi 1488192508  169 DLNEKIAQRPGPMELVEKNILP 190
Cdd:pfam02755    1 SLERKLSHRPTREELVERNILP 22
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
81-105 9.48e-05

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 40.15  E-value: 9.48e-05
                            10        20
                    ....*....|....*....|....*
gi 1488192508    81 VLQLKLQQRRTREELVSQGIMPPLK 105
Cdd:smart00707    2 VLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 126-148 4.42e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 38.41  E-value: 4.42e-04
                           10        20
                   ....*....|....*....|...
gi 1488192508  126 LKRKIRSRPERSELVRMHILEET 148
Cdd:pfam02755    2 LERKLSHRPTREELVERNILPED 24
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 82-103 9.69e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 37.25  E-value: 9.69e-04
                           10        20
                   ....*....|....*....|..
gi 1488192508   82 LQLKLQQRRTREELVSQGIMPP 103
Cdd:pfam02755    2 LERKLSHRPTREELVERNILPE 23
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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