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Conserved domains on  [gi|1279652341|ref|NP_079101|]
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podocan-like protein 1 isoform 1 precursor [Homo sapiens]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
70-316 6.01e-24

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 103.86  E-value: 6.01e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  70 QHLSLQNNQLQELPyNELSRLSGLRTLNLHNNLISSegLPDEaFESLTQLQHLCVAHNKLSVAPQFLPR--SLRVADLAA 147
Cdd:COG4886   116 ESLDLSGNQLTDLP-EELANLTNLKELDLSNNQLTD--LPEP-LGNLTNLKSLDLSNNQLTDLPEELGNltNLKELDLSN 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 148 NQVMEIfPLTFGEKPALRSVYLHNNQLSNAglpPDAFRGSEAIATLSLSNNQLSYLPP-SLPPSLERLHLQNNLISKVPr 226
Cdd:COG4886   192 NQITDL-PEPLGNLTNLEELDLSGNQLTDL---PEPLANLTNLETLDLSNNQLTDLPElGNLTNLEELDLSNNQLTDLP- 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 227 gALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGL 306
Cdd:COG4886   267 -PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLS 345

                         250
                  ....*....|
gi 1279652341 307 RYLLLQHNQL 316
Cdd:COG4886   346 LLALLTLLLL 355
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
209-475 6.81e-18

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 85.76  E-value: 6.81e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 209 PSLERLHLQNNLiskvprgALSRQTQLRELYLQHNQLTDSGLDattFSKLHSLEYLDLSHNQLTTVPAGLPR--TLAILH 286
Cdd:COG4886    96 TNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEE---LANLTNLKELDLSNNQLTDLPEPLGNltNLKSLD 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 287 LGRNRIRQVEAArLHGARGLRYLLLQHNQLGSsgLPAgALRPLRGLHTLHLYGNGLDRVPPALPR--RLRALVLPHNHVA 364
Cdd:COG4886   166 LSNNQLTDLPEE-LGNLTNLKELDLSNNQITD--LPE-PLGNLTNLEELDLSGNQLTDLPEPLANltNLETLDLSNNQLT 241

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 365 ALgaRDLVATPGLTELNLAYNRLASArvhhRAFRRLRALRSLDLAGNQLTRLPM-GLPTGLRTLQLQRNQLRMLEPEPLA 443
Cdd:COG4886   242 DL--PELGNLTNLEELDLSNNQLTDL----PPLANLTNLKTLDLSNNQLTDLKLkELELLLGLNSLLLLLLLLNLLELLI 315

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1279652341 444 GLDQLRELSLAHNRLRVGDIGPGTWHELQALQ 475
Cdd:COG4886   316 LLLLLTTLLLLLLLLKGLLVTLTTLALSLSLL 347
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
70-316 6.01e-24

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 103.86  E-value: 6.01e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  70 QHLSLQNNQLQELPyNELSRLSGLRTLNLHNNLISSegLPDEaFESLTQLQHLCVAHNKLSVAPQFLPR--SLRVADLAA 147
Cdd:COG4886   116 ESLDLSGNQLTDLP-EELANLTNLKELDLSNNQLTD--LPEP-LGNLTNLKSLDLSNNQLTDLPEELGNltNLKELDLSN 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 148 NQVMEIfPLTFGEKPALRSVYLHNNQLSNAglpPDAFRGSEAIATLSLSNNQLSYLPP-SLPPSLERLHLQNNLISKVPr 226
Cdd:COG4886   192 NQITDL-PEPLGNLTNLEELDLSGNQLTDL---PEPLANLTNLETLDLSNNQLTDLPElGNLTNLEELDLSNNQLTDLP- 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 227 gALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGL 306
Cdd:COG4886   267 -PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLS 345

                         250
                  ....*....|
gi 1279652341 307 RYLLLQHNQL 316
Cdd:COG4886   346 LLALLTLLLL 355
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
188-442 4.61e-20

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 93.61  E-value: 4.61e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 188 EAIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRgalSRQTQLRELYLQHNQLTDsgLDATTFSKLHSleyLDLS 267
Cdd:PRK15370  199 EQITTLILDNNELKSLPENLQGNIKTLYANSNQLTSIPA---TLPDTIQEMELSINRITE--LPERLPSALQS---LDLF 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 268 HNQLTTVPAGLPRTLAILHLGRNRIRQVEAarlHGARGLRYLLLQHNQLgsSGLPAgALRPlrGLHTLHLYGNGLDRVPP 347
Cdd:PRK15370  271 HNKISCLPENLPEELRYLSVYDNSIRTLPA---HLPSGITHLNVQSNSL--TALPE-TLPP--GLKTLEAGENALTSLPA 342

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 348 ALPRRLRALVLPHNHVAALGArdlVATPGLTElnlaynrlasarvhhrafrrlralrsLDLAGNQLTRLPMGLPTGLRTL 427
Cdd:PRK15370  343 SLPPELQVLDVSKNQITVLPE---TLPPTITT--------------------------LDVSRNALTNLPENLPAALQIM 393

                         250
                  ....*....|....*
gi 1279652341 428 QLQRNQLRMLePEPL 442
Cdd:PRK15370  394 QASRNNLVRL-PESL 407
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
209-475 6.81e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 85.76  E-value: 6.81e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 209 PSLERLHLQNNLiskvprgALSRQTQLRELYLQHNQLTDSGLDattFSKLHSLEYLDLSHNQLTTVPAGLPR--TLAILH 286
Cdd:COG4886    96 TNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEE---LANLTNLKELDLSNNQLTDLPEPLGNltNLKSLD 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 287 LGRNRIRQVEAArLHGARGLRYLLLQHNQLGSsgLPAgALRPLRGLHTLHLYGNGLDRVPPALPR--RLRALVLPHNHVA 364
Cdd:COG4886   166 LSNNQLTDLPEE-LGNLTNLKELDLSNNQITD--LPE-PLGNLTNLEELDLSGNQLTDLPEPLANltNLETLDLSNNQLT 241

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 365 ALgaRDLVATPGLTELNLAYNRLASArvhhRAFRRLRALRSLDLAGNQLTRLPM-GLPTGLRTLQLQRNQLRMLEPEPLA 443
Cdd:COG4886   242 DL--PELGNLTNLEELDLSNNQLTDL----PPLANLTNLKTLDLSNNQLTDLKLkELELLLGLNSLLLLLLLLNLLELLI 315

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1279652341 444 GLDQLRELSLAHNRLRVGDIGPGTWHELQALQ 475
Cdd:COG4886   316 LLLLLTTLLLLLLLLKGLLVTLTTLALSLSLL 347
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 193-381 5.10e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 65.19  E-value: 5.10e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 193 LSLSNNQLSYLP-PSLPPSLERLHLQNNLISKVPrgALSRQTQLRELYLQHNQLTD-SGLDAttfskLHSLEYLDLSHNQ 270
Cdd:cd21340     7 LYLNDKNITKIDnLSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKiENLEN-----LVNLKKLYLGGNR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 271 LTTVpAGL--PRTLAILHLGRNRIRQ-----VEAARLHG-ARGLRYLLLQHNQLGSSglpaGALRPLRGLHTLHLYGNGL 342
Cdd:cd21340    80 ISVV-EGLenLTNLEELHIENQRLPPgekltFDPRSLAAlSNSLRVLNISGNNIDSL----EPLAPLRNLEQLDASNNQI 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1279652341 343 DRVPPALP-----RRLRALVLPHNHVAAL-GARD--LVATPGLTELN 381
Cdd:cd21340   155 SDLEELLDllsswPSLRELDLTGNPVCKKpKYRDkiILASKSLEVLD 201
LRR_8 pfam13855
Leucine rich repeat;
209-271 9.04e-11

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 57.15  E-value: 9.04e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1279652341 209 PSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTdsGLDATTFSKLHSLEYLDLSHNQL 271
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLT--TLSPGAFSGLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
264-491 6.62e-07

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 52.01  E-value: 6.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 264 LDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVeAARLHGarGLRYLLLQHNQLGSsgLPAGAlrPlRGLHTLHLYGNGLD 343
Cdd:PRK15370  183 LRLKILGLTTIPACIPEQITTLILDNNELKSL-PENLQG--NIKTLYANSNQLTS--IPATL--P-DTIQEMELSINRIT 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 344 RVPPALPRRLRALVLPHNHVAALgardlvatPGLTELNLAYnrlasarvhhrafrrlralrsLDLAGNQLTRLPMGLPTG 423
Cdd:PRK15370  255 ELPERLPSALQSLDLFHNKISCL--------PENLPEELRY---------------------LSVYDNSIRTLPAHLPSG 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 424 LRTLQLQRNQLRMLePEPLA-GLD------------------QLRELSLAHNRLRV-GDIGPGTwheLQALQVRHRLVSH 483
Cdd:PRK15370  306 ITHLNVQSNSLTAL-PETLPpGLKtleagenaltslpaslppELQVLDVSKNQITVlPETLPPT---ITTLDVSRNALTN 381


                  ....*...
gi 1279652341 484 tVPRAPPS 491
Cdd:PRK15370  382 -LPENLPA 388
LRR_8 pfam13855
Leucine rich repeat;
405-458 1.14e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.90  E-value: 1.14e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1279652341 405 SLDLAGNQLTRLPMGLPTG---LRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRL 458
Cdd:pfam13855   5 SLDLSNNRLTSLDDGAFKGlsnLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 194-458 8.65e-05

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 44.65  E-value: 8.65e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 194 SLSNNQLSYLPPSL--PPSLERLHLQNNLISKVPRG------ALSRQTQLRELYLQHNQLTDSGldATTFSKLH---SLE 262
Cdd:cd00116    34 TLGEEAAKALASALrpQPSLKELCLSLNETGRIPRGlqsllqGLTKGCGLQELDLSDNALGPDG--CGVLESLLrssSLQ 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 263 YLDLSHNQLttvpaglprtlailhlGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLP--AGALRPLRGLHTLHLYGN 340
Cdd:cd00116   112 ELKLNNNGL----------------GDRGLRLLAKGLKDLPPALEKLVLGRNRLEGASCEalAKALRANRDLKELNLANN 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 341 GL-DRVPPALPR------RLRALVLPHNHVAALGARDLVATP----GLTELNLAYNRLASARVHHRAFRRLRALRSL--- 406
Cdd:cd00116   176 GIgDAGIRALAEglkancNLEVLDLNNNGLTDEGASALAETLaslkSLEVLNLGDNNLTDAGAAALASALLSPNISLltl 255

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1279652341 407 DLAGNQLTRLpmglptGLRTLQlqrnqlrmlepEPLAGLDQLRELSLAHNRL 458
Cdd:cd00116   256 SLSCNDITDD------GAKDLA-----------EVLAEKESLLELDLRGNKF 290
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
70-316 6.01e-24

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 103.86  E-value: 6.01e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  70 QHLSLQNNQLQELPyNELSRLSGLRTLNLHNNLISSegLPDEaFESLTQLQHLCVAHNKLSVAPQFLPR--SLRVADLAA 147
Cdd:COG4886   116 ESLDLSGNQLTDLP-EELANLTNLKELDLSNNQLTD--LPEP-LGNLTNLKSLDLSNNQLTDLPEELGNltNLKELDLSN 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 148 NQVMEIfPLTFGEKPALRSVYLHNNQLSNAglpPDAFRGSEAIATLSLSNNQLSYLPP-SLPPSLERLHLQNNLISKVPr 226
Cdd:COG4886   192 NQITDL-PEPLGNLTNLEELDLSGNQLTDL---PEPLANLTNLETLDLSNNQLTDLPElGNLTNLEELDLSNNQLTDLP- 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 227 gALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGL 306
Cdd:COG4886   267 -PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLS 345

                         250
                  ....*....|
gi 1279652341 307 RYLLLQHNQL 316
Cdd:COG4886   346 LLALLTLLLL 355
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
72-448 3.16e-23

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 101.93  E-value: 3.16e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  72 LSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPrSLRVADLAANQvm 151
Cdd:COG4886    31 LLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLT-NLTELDLSGNE-- 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 152 EIFPLTfgekpALRSVYLHNNQLSNAglpPDAFRGSEAIATLSLSNNQLSYLPPSLP--PSLERLHLQNNLISKVPRgAL 229
Cdd:COG4886   108 ELSNLT-----NLESLDLSGNQLTDL---PEELANLTNLKELDLSNNQLTDLPEPLGnlTNLKSLDLSNNQLTDLPE-EL 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 230 SRQTQLRELYLQHNQLTDSGldaTTFSKLHSLEYLDLSHNQLTTVPAGLPR--TLAILHLGRNRIRQVEAarLHGARGLR 307
Cdd:COG4886   179 GNLTNLKELDLSNNQITDLP---EPLGNLTNLEELDLSGNQLTDLPEPLANltNLETLDLSNNQLTDLPE--LGNLTNLE 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 308 YLLLQHNQLgsSGLPagALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRL 387
Cdd:COG4886   254 ELDLSNNQL--TDLP--PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLL 329

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1279652341 388 ASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQL 448
Cdd:COG4886   330 LKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLL 390
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
188-442 4.61e-20

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 93.61  E-value: 4.61e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 188 EAIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRgalSRQTQLRELYLQHNQLTDsgLDATTFSKLHSleyLDLS 267
Cdd:PRK15370  199 EQITTLILDNNELKSLPENLQGNIKTLYANSNQLTSIPA---TLPDTIQEMELSINRITE--LPERLPSALQS---LDLF 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 268 HNQLTTVPAGLPRTLAILHLGRNRIRQVEAarlHGARGLRYLLLQHNQLgsSGLPAgALRPlrGLHTLHLYGNGLDRVPP 347
Cdd:PRK15370  271 HNKISCLPENLPEELRYLSVYDNSIRTLPA---HLPSGITHLNVQSNSL--TALPE-TLPP--GLKTLEAGENALTSLPA 342

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 348 ALPRRLRALVLPHNHVAALGArdlVATPGLTElnlaynrlasarvhhrafrrlralrsLDLAGNQLTRLPMGLPTGLRTL 427
Cdd:PRK15370  343 SLPPELQVLDVSKNQITVLPE---TLPPTITT--------------------------LDVSRNALTNLPENLPAALQIM 393

                         250
                  ....*....|....*
gi 1279652341 428 QLQRNQLRMLePEPL 442
Cdd:PRK15370  394 QASRNNLVRL-PESL 407
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
32-279 6.46e-20

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 93.22  E-value: 6.46e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  32 LQPLPRACPlrcscPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYN--------ELSRlsglrtlnlhNNLI 103
Cdd:PRK15370  190 LTTIPACIP-----EQITTLILDNNELKSLPENLQGNIKTLYANSNQLTSIPATlpdtiqemELSI----------NRIT 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 104 S-SEGLPdeafeslTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEI---FPLTFGEkpalrsVYLHNNQLS--NA 177
Cdd:PRK15370  255 ElPERLP-------SALQSLDLFHNKISCLPENLPEELRYLSVYDNSIRTLpahLPSGITH------LNVQSNSLTalPE 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 178 GLPPDafrgseaIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRgalSRQTQLRELYLQHNQLTD--SGLDAttf 255
Cdd:PRK15370  322 TLPPG-------LKTLEAGENALTSLPASLPPELQVLDVSKNQITVLPE---TLPPTITTLDVSRNALTNlpENLPA--- 388

                         250       260
                  ....*....|....*....|....
gi 1279652341 256 sklhSLEYLDLSHNQLTTVPAGLP 279
Cdd:PRK15370  389 ----ALQIMQASRNNLVRLPESLP 408
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
192-481 2.06e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 87.30  E-value: 2.06e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 192 TLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQltdsgldatTFSKLHSLEYLDLSHNQL 271
Cdd:COG4886    55 LLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNLESLDLSGNQL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 272 TTVPAGLPR--TLAILHLGRNRIRQVEAArLHGARGLRYLLLQHNQLgsSGLPAgALRPLRGLHTLHLYGNGLDRVPPAL 349
Cdd:COG4886   126 TDLPEELANltNLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQL--TDLPE-ELGNLTNLKELDLSNNQITDLPEPL 201

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 350 --PRRLRALVLPHNHVAALGArDLVATPGLTELNLAYNRLASArvhhRAFRRLRALRSLDLAGNQLTRLPMGLP-TGLRT 426
Cdd:COG4886   202 gnLTNLEELDLSGNQLTDLPE-PLANLTNLETLDLSNNQLTDL----PELGNLTNLEELDLSNNQLTDLPPLANlTNLKT 276

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1279652341 427 LQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQVRHRLV 481
Cdd:COG4886   277 LDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLK 331
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
209-475 6.81e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 85.76  E-value: 6.81e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 209 PSLERLHLQNNLiskvprgALSRQTQLRELYLQHNQLTDSGLDattFSKLHSLEYLDLSHNQLTTVPAGLPR--TLAILH 286
Cdd:COG4886    96 TNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEE---LANLTNLKELDLSNNQLTDLPEPLGNltNLKSLD 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 287 LGRNRIRQVEAArLHGARGLRYLLLQHNQLGSsgLPAgALRPLRGLHTLHLYGNGLDRVPPALPR--RLRALVLPHNHVA 364
Cdd:COG4886   166 LSNNQLTDLPEE-LGNLTNLKELDLSNNQITD--LPE-PLGNLTNLEELDLSGNQLTDLPEPLANltNLETLDLSNNQLT 241

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 365 ALgaRDLVATPGLTELNLAYNRLASArvhhRAFRRLRALRSLDLAGNQLTRLPM-GLPTGLRTLQLQRNQLRMLEPEPLA 443
Cdd:COG4886   242 DL--PELGNLTNLEELDLSNNQLTDL----PPLANLTNLKTLDLSNNQLTDLKLkELELLLGLNSLLLLLLLLNLLELLI 315

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1279652341 444 GLDQLRELSLAHNRLRVGDIGPGTWHELQALQ 475
Cdd:COG4886   316 LLLLLTTLLLLLLLLKGLLVTLTTLALSLSLL 347
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 46-463 5.58e-17

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 84.13  E-value: 5.58e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  46 PRVDTVDCDGLDLR-VFPDNI---TRAAQHLSLQNNQLQelpyNELSR--LSGLRTLNLHNNLISSEgLPDE--AFESLT 117
Cdd:PLN00113   93 PYIQTINLSNNQLSgPIPDDIfttSSSLRYLNLSNNNFT----GSIPRgsIPNLETLDLSNNMLSGE-IPNDigSFSSLK 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 118 QLQ---HLCVAHNKLSVAPQflpRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSnaGLPPDAFRGSEAIATLS 194
Cdd:PLN00113  168 VLDlggNVLVGKIPNSLTNL---TSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLS--GEIPYEIGGLTSLNHLD 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 195 LSNNQLS-YLPPSLP--PSLERLHL-QNNLISKVPRGALSRQtQLRELYLQHNQLtdSGLDATTFSKLHSLEYLDLSHNQ 270
Cdd:PLN00113  243 LVYNNLTgPIPSSLGnlKNLQYLFLyQNKLSGPIPPSIFSLQ-KLISLDLSDNSL--SGEIPELVIQLQNLEILHLFSNN 319

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 271 LT-TVPAG---LPRtLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLgSSGLPAGaLRPLRGLHTLHLYGNGLD-RV 345
Cdd:PLN00113  320 FTgKIPVAltsLPR-LQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNL-TGEIPEG-LCSSGNLFKLILFSNSLEgEI 396

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 346 PPALP--RRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLaSARVhHRAFRRLRALRSLDLAGNqltRLPMGLP-- 421
Cdd:PLN00113  397 PKSLGacRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNL-QGRI-NSRKWDMPSLQMLSLARN---KFFGGLPds 471

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 1279652341 422 ---TGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRvGDI 463
Cdd:PLN00113  472 fgsKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLS-GEI 515
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
54-314 8.59e-17

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 83.59  E-value: 8.59e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  54 DGLDLRVFPDNITRAAQHLSLQNNQLQELPYNelsrlsglrtlnLHNNLisseglpdeafesltqlQHLCVAHNKLSVAP 133
Cdd:PRK15370  186 KILGLTTIPACIPEQITTLILDNNELKSLPEN------------LQGNI-----------------KTLYANSNQLTSIP 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 134 QFLPRSLRVADLAANQVMEI---FPltfgekPALRSVYLHNNQLSnaGLP---PDAFRG---------------SEAIAT 192
Cdd:PRK15370  237 ATLPDTIQEMELSINRITELperLP------SALQSLDLFHNKIS--CLPenlPEELRYlsvydnsirtlpahlPSGITH 308

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 193 LSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRgalSRQTQLRELYLQHNQLT--DSGLDATtfsklhsLEYLDLSHNQ 270
Cdd:PRK15370  309 LNVQSNSLTALPETLPPGLKTLEAGENALTSLPA---SLPPELQVLDVSKNQITvlPETLPPT-------ITTLDVSRNA 378

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1279652341 271 LTTVPAGLPRTLAILHLGRNRIRQVEAARLH----GARGLRyLLLQHN 314
Cdd:PRK15370  379 LTNLPENLPAALQIMQASRNNLVRLPESLPHfrgeGPQPTR-IIVEYN 425
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 64-458 3.38e-16

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 81.82  E-value: 3.38e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  64 NITRAaQHLSLQNNQLQ-ELPyNELSRLSGLRTLNL-HNNLisSEGLPDEAFEsLTQLQHLcvahnklsvapqflprslr 141
Cdd:PLN00113  186 NLTSL-EFLTLASNQLVgQIP-RELGQMKSLKWIYLgYNNL--SGEIPYEIGG-LTSLNHL------------------- 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 142 vaDLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAgLPPDAFrGSEAIATLSLSNNQLSYLPPSLP---PSLERLHL-Q 217
Cdd:PLN00113  242 --DLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGP-IPPSIF-SLQKLISLDLSDNSLSGEIPELViqlQNLEILHLfS 317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 218 NNLISKVPRgALSRQTQLRELYLQHNQLtdSGLDATTFSKLHSLEYLDLSHNQLT-TVPAGLPRT--LAILHLGRNRIRQ 294
Cdd:PLN00113  318 NNFTGKIPV-ALTSLPRLQVLQLWSNKF--SGEIPKNLGKHNNLTVLDLSTNNLTgEIPEGLCSSgnLFKLILFSNSLEG 394

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 295 VEAARLHGARGLRYLLLQHNQLgSSGLPAGALRpLRGLHTLHLYGNGL---------------------DRVPPALP--- 350
Cdd:PLN00113  395 EIPKSLGACRSLRRVRLQDNSF-SGELPSEFTK-LPLVYFLDISNNNLqgrinsrkwdmpslqmlslarNKFFGGLPdsf 472

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 351 --RRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASarVHHRAFRRLRALRSLDLAGNQLT-RLPMG---LPTgL 424
Cdd:PLN00113  473 gsKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSG--EIPDELSSCKKLVSLDLSHNQLSgQIPASfseMPV-L 549

                         410       420       430
                  ....*....|....*....|....*....|....
gi 1279652341 425 RTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRL 458
Cdd:PLN00113  550 SQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHL 583
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
171-458 3.61e-13

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 72.12  E-value: 3.61e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 171 NNQLSNAGLPPDafrgseaIATLSLSNNQLSYLPpSLPPSLERLHLQNNLISKVPrgalSRQTQLRELYLQHNQLTDSGL 250
Cdd:PRK15387  232 NNLTSLPALPPE-------LRTLEVSGNQLTSLP-VLPPGLLELSIFSNPLTHLP----ALPSGLCKLWIFGNQLTSLPV 299

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 251 DATtfsklhSLEYLDLSHNQLTTVPAgLPRTLAILHLGRNRIRQVEAArlhgARGLRYLLLQHNQLGS-SGLPAGalrpl 329
Cdd:PRK15387  300 LPP------GLQELSVSDNQLASLPA-LPSELCKLWAYNNQLTSLPTL----PSGLQELSVSDNQLASlPTLPSE----- 363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 330 rgLHTLHLYGNGLDRVPpALPRrlralvlphnhvaalgardlvatpGLTELNLAYNRLASARVhhrafrRLRALRSLDLA 409
Cdd:PRK15387  364 --LYKLWAYNNRLTSLP-ALPS------------------------GLKELIVSGNRLTSLPV------LPSELKELMVS 410

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1279652341 410 GNQLTRLPMgLPTGLRTLQLQRNQLRMLePEPLAGLDQLRELSLAHNRL 458
Cdd:PRK15387  411 GNRLTSLPM-LPSGLLSLSVYRNQLTRL-PESLIHLSSETTVNLEGNPL 457
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 193-381 5.10e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 65.19  E-value: 5.10e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 193 LSLSNNQLSYLP-PSLPPSLERLHLQNNLISKVPrgALSRQTQLRELYLQHNQLTD-SGLDAttfskLHSLEYLDLSHNQ 270
Cdd:cd21340     7 LYLNDKNITKIDnLSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKiENLEN-----LVNLKKLYLGGNR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 271 LTTVpAGL--PRTLAILHLGRNRIRQ-----VEAARLHG-ARGLRYLLLQHNQLGSSglpaGALRPLRGLHTLHLYGNGL 342
Cdd:cd21340    80 ISVV-EGLenLTNLEELHIENQRLPPgekltFDPRSLAAlSNSLRVLNISGNNIDSL----EPLAPLRNLEQLDASNNQI 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1279652341 343 DRVPPALP-----RRLRALVLPHNHVAAL-GARD--LVATPGLTELN 381
Cdd:cd21340   155 SDLEELLDllsswPSLRELDLTGNPVCKKpKYRDkiILASKSLEVLD 201
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 71-340 8.33e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 64.81  E-value: 8.33e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  71 HLSLQNNQLQELPynELSRLSGLRTLNLHNNLISS-EGLpdeafESLTQLQHLcvahnklsvapqflprslrvadlaanq 149
Cdd:cd21340     6 HLYLNDKNITKID--NLSLCKNLKVLYLYDNKITKiENL-----EFLTNLTHL--------------------------- 51

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 150 vmeifpltfgekpalrsvYLHNNQLSnaglppdafrgseaiatlSLSNnqLSYLppslpPSLERLHLQNNLISKVprGAL 229
Cdd:cd21340    52 ------------------YLQNNQIE------------------KIEN--LENL-----VNLKKLYLGGNRISVV--EGL 86

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 230 SRQTQLRELYLQHNQLtDSGL-----DATTFSKLHSLEYLDLSHNQLTTVpaglpRTLAILhlgrnrirqveaarlhgaR 304
Cdd:cd21340    87 ENLTNLEELHIENQRL-PPGEkltfdPRSLAALSNSLRVLNISGNNIDSL-----EPLAPL------------------R 142

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1279652341 305 GLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGN 340
Cdd:cd21340   143 NLEQLDASNNQISDLEELLDLLSSWPSLRELDLTGN 178
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 138-474 2.31e-11

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 65.58  E-value: 2.31e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 138 RSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYlpPSLPPSLERLHLQ 217
Cdd:COG5238    64 RFEGQGDPGLNPVALEKAAEAFPTQLLVVDWEGAEEVSPVALAETATAVATPPPDLRRIMAKTLE--DSLILYLALPRRI 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 218 NNLISKVPrgalSRQTQ-LRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA-------GLPRTLAILHLGR 289
Cdd:COG5238   142 NLIQVLKD----PLGGNaVHLLGLAARLGLLAAISMAKALQNNSVETVYLGCNQIGDEGIeelaealTQNTTVTTLWLKR 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 290 NRI--RQVE--AARLHGARGLRYLLLQHNQLGSSGLP--AGALRPLRGLHTLHLYGN-----GLDRVPPALPRR--LRAL 356
Cdd:COG5238   218 NPIgdEGAEilAEALKGNKSLTTLDLSNNQIGDEGVIalAEALKNNTTVETLYLSGNqigaeGAIALAKALQGNttLTSL 297

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 357 VLPHNHVAALGARDLV----ATPGLTELNLAYNR--------LASARVHHRAFRrlralrSLDLAGNQLT--------RL 416
Cdd:COG5238   298 DLSVNRIGDEGAIALAeglqGNKTLHTLNLAYNGigaqgaiaLAKALQENTTLH------SLDLSDNQIGdegaialaKY 371

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1279652341 417 PMGLPTgLRTLQLQRNQLRMLEPEPLAglDQLRELSLAHNRLRVGDIGPGTWHELQAL 474
Cdd:COG5238   372 LEGNTT-LRELNLGKNNIGKQGAEALI--DALQTNRLHTLILDGNLIGAEAQQRLEQL 426
LRR_8 pfam13855
Leucine rich repeat;
209-271 9.04e-11

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 57.15  E-value: 9.04e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1279652341 209 PSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTdsGLDATTFSKLHSLEYLDLSHNQL 271
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLT--TLSPGAFSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 67-320 1.36e-09

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 59.29  E-value: 1.36e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  67 RAAQHLSLQNNQLQELPYN------ELSRLSGLRTLNLHNNLISSEGLPdeAFESLTQ---LQHLCVAHNKLSVAP-QFL 136
Cdd:cd00116    51 PSLKELCLSLNETGRIPRGlqsllqGLTKGCGLQELDLSDNALGPDGCG--VLESLLRsssLQELKLNNNGLGDRGlRLL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 137 PRSLRvaDLaanqvmeifpltfgeKPALRSVYLHNNQLSNAGLPP--DAFRGSEAIATLSLSNNQLsylppsLPPSLERL 214
Cdd:cd00116   129 AKGLK--DL---------------PPALEKLVLGRNRLEGASCEAlaKALRANRDLKELNLANNGI------GDAGIRAL 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 215 HLqnnliskvprgALSRQTQLRELYLQHNQLTDSG--LDATTFSKLHSLEYLDLSHNQLTTVPAglpRTLAilhlgrnri 292
Cdd:cd00116   186 AE-----------GLKANCNLEVLDLNNNGLTDEGasALAETLASLKSLEVLNLGDNNLTDAGA---AALA--------- 242

                         250       260
                  ....*....|....*....|....*...
gi 1279652341 293 rqveAARLHGARGLRYLLLQHNQLGSSG 320
Cdd:cd00116   243 ----SALLSPNISLLTLSLSCNDITDDG 266
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 59-387 3.05e-09

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 59.03  E-value: 3.05e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  59 RVFPDNITRAAQHLSLQNNQLQELPYNELSRLSG---LRTLNLHNNLISSEGLPD--EAFESLTQLQHLCVAHNKLsvap 133
Cdd:COG5238   145 QVLKDPLGGNAVHLLGLAARLGLLAAISMAKALQnnsVETVYLGCNQIGDEGIEElaEALTQNTTVTTLWLKRNPI---- 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 134 qflprslrvadlaANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLppdafrgsEAIATlSLSNNQlsylppslppSLER 213
Cdd:COG5238   221 -------------GDEGAEILAEALKGNKSLTTLDLSNNQIGDEGV--------IALAE-ALKNNT----------TVET 268

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 214 LHLQNNLIS----KVPRGALSRQTQLRELYLQHNQLTDSGldATTFSKLhsleyldLSHNQlttvpaglprTLAILHLGR 289
Cdd:COG5238   269 LYLSGNQIGaegaIALAKALQGNTTLTSLDLSVNRIGDEG--AIALAEG-------LQGNK----------TLHTLNLAY 329

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 290 NRIRQVEAARLhgarglrylllqhnqlgssglpAGALRPLRGLHTLHLYGNGLDrvppalprrlralvlphNHVAALGAR 369
Cdd:COG5238   330 NGIGAQGAIAL----------------------AKALQENTTLHSLDLSDNQIG-----------------DEGAIALAK 370

                         330
                  ....*....|....*...
gi 1279652341 370 DLVATPGLTELNLAYNRL 387
Cdd:COG5238   371 YLEGNTTLRELNLGKNNI 388
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
122-349 3.34e-09

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 59.41  E-value: 3.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 122 LCVAHNKLSVAPQfLPRSLRVADLAANQVMEIFPLtfgeKPALRSVYLHNNQLSNAGLPPdafrgsEAIATLSLSNNQLS 201
Cdd:PRK15387  227 LVIPDNNLTSLPA-LPPELRTLEVSGNQLTSLPVL----PPGLLELSIFSNPLTHLPALP------SGLCKLWIFGNQLT 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 202 YLPpSLPPSLERLHLQNNLISKVPrgalSRQTQLRELYLQHNQLtdsgldaTTFSKLHS-LEYLDLSHNQLTTVPAgLPR 280
Cdd:PRK15387  296 SLP-VLPPGLQELSVSDNQLASLP----ALPSELCKLWAYNNQL-------TSLPTLPSgLQELSVSDNQLASLPT-LPS 362

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 281 TLAILHLGRNRIRQVEAArlhgARGLRYLLLQHNQLGSSGLPAGALRPL--------------RGLHTLHLYGNGLDRVP 346
Cdd:PRK15387  363 ELYKLWAYNNRLTSLPAL----PSGLKELIVSGNRLTSLPVLPSELKELmvsgnrltslpmlpSGLLSLSVYRNQLTRLP 438


                  ...
gi 1279652341 347 PAL 349
Cdd:PRK15387  439 ESL 441
LRR_8 pfam13855
Leucine rich repeat;
233-292 6.68e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 49.06  E-value: 6.68e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1279652341 233 TQLRELYLQHNQLTDsgLDATTFSKLHSLEYLDLSHNQLTTVP----AGLPRtLAILHLGRNRI 292
Cdd:pfam13855   1 PNLRSLDLSNNRLTS--LDDGAFKGLSNLKVLDLSNNLLTTLSpgafSGLPS-LRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 67-226 1.11e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 52.48  E-value: 1.11e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  67 RAAQHLSLQNNQLQELPynELSRLSGLRTLNLHNNLISS-EGLpdeafESLTQLQHLCVAHNKLSV-----APQFLpRSL 140
Cdd:cd21340    24 KNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKiENL-----ENLVNLKKLYLGGNRISVvegleNLTNL-EEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 141 RVAD--LAANQVMEIFPLT-FGEKPALRSVYLHNNQLSNaglpPDAFRGSEAIATLSLSNNQLSYLPPSLP-----PSLE 212
Cdd:cd21340    96 HIENqrLPPGEKLTFDPRSlAALSNSLRVLNISGNNIDS----LEPLAPLRNLEQLDASNNQISDLEELLDllsswPSLR 171

                         170
                  ....*....|....
gi 1279652341 213 RLHLQNNLISKVPR 226
Cdd:cd21340   172 ELDLTGNPVCKKPK 185
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
264-491 6.62e-07

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 52.01  E-value: 6.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 264 LDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVeAARLHGarGLRYLLLQHNQLGSsgLPAGAlrPlRGLHTLHLYGNGLD 343
Cdd:PRK15370  183 LRLKILGLTTIPACIPEQITTLILDNNELKSL-PENLQG--NIKTLYANSNQLTS--IPATL--P-DTIQEMELSINRIT 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 344 RVPPALPRRLRALVLPHNHVAALgardlvatPGLTELNLAYnrlasarvhhrafrrlralrsLDLAGNQLTRLPMGLPTG 423
Cdd:PRK15370  255 ELPERLPSALQSLDLFHNKISCL--------PENLPEELRY---------------------LSVYDNSIRTLPAHLPSG 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 424 LRTLQLQRNQLRMLePEPLA-GLD------------------QLRELSLAHNRLRV-GDIGPGTwheLQALQVRHRLVSH 483
Cdd:PRK15370  306 ITHLNVQSNSLTAL-PETLPpGLKtleagenaltslpaslppELQVLDVSKNQITVlPETLPPT---ITTLDVSRNALTN 381


                  ....*...
gi 1279652341 484 tVPRAPPS 491
Cdd:PRK15370  382 -LPENLPA 388
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 70-210 3.00e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 50.23  E-value: 3.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  70 QHLSL-QNNQLQELPynELSRLSGLRTLNLHNNLISseGLPDEAFESLTQLQHLCVAHNKLS-VAPQFLP--RSLRVADL 145
Cdd:PLN00113  455 QMLSLaRNKFFGGLP--DSFGSKRLENLDLSRNQFS--GAVPRKLGSLSELMQLKLSENKLSgEIPDELSscKKLVSLDL 530

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1279652341 146 AANQVMEIFPLTFGEKPALRSVYLHNNQLSnaGLPPDAFRGSEAIATLSLSNNQLSylpPSLPPS 210
Cdd:PLN00113  531 SHNQLSGQIPASFSEMPVLSQLDLSQNQLS--GEIPKNLGNVESLVQVNISHNHLH---GSLPST 590
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
27-175 6.09e-06

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 48.92  E-value: 6.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  27 HLGESLQPLPRACPLRCSCPR-----VDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPY-------------NELS 88
Cdd:PRK15370  259 RLPSALQSLDLFHNKISCLPEnlpeeLRYLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALPEtlppglktleageNALT 338

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  89 RLSG-----LRTLNLHNNLIS--SEGLPdeafeslTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVM---EIFPLTF 158
Cdd:PRK15370  339 SLPAslppeLQVLDVSKNQITvlPETLP-------PTITTLDVSRNALTNLPENLPAALQIMQASRNNLVrlpESLPHFR 411

                         170
                  ....*....|....*..
gi 1279652341 159 GEKPALRSVYLHNNQLS 175
Cdd:PRK15370  412 GEGPQPTRIIVEYNPFS 428
LRR_8 pfam13855
Leucine rich repeat;
70-129 9.83e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.90  E-value: 9.83e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  70 QHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSegLPDEAFESLTQLQHLCVAHNKL 129
Cdd:pfam13855   4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT--LSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
192-245 1.11e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.90  E-value: 1.11e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1279652341 192 TLSLSNNQLSYLPPSL---PPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQL 245
Cdd:pfam13855   5 SLDLSNNRLTSLDDGAfkgLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
405-458 1.14e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.90  E-value: 1.14e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1279652341 405 SLDLAGNQLTRLPMGLPTG---LRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRL 458
Cdd:pfam13855   5 SLDLSNNRLTSLDDGAFKGlsnLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 194-458 8.65e-05

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 44.65  E-value: 8.65e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 194 SLSNNQLSYLPPSL--PPSLERLHLQNNLISKVPRG------ALSRQTQLRELYLQHNQLTDSGldATTFSKLH---SLE 262
Cdd:cd00116    34 TLGEEAAKALASALrpQPSLKELCLSLNETGRIPRGlqsllqGLTKGCGLQELDLSDNALGPDG--CGVLESLLrssSLQ 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 263 YLDLSHNQLttvpaglprtlailhlGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLP--AGALRPLRGLHTLHLYGN 340
Cdd:cd00116   112 ELKLNNNGL----------------GDRGLRLLAKGLKDLPPALEKLVLGRNRLEGASCEalAKALRANRDLKELNLANN 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 341 GL-DRVPPALPR------RLRALVLPHNHVAALGARDLVATP----GLTELNLAYNRLASARVHHRAFRRLRALRSL--- 406
Cdd:cd00116   176 GIgDAGIRALAEglkancNLEVLDLNNNGLTDEGASALAETLaslkSLEVLNLGDNNLTDAGAAALASALLSPNISLltl 255

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1279652341 407 DLAGNQLTRLpmglptGLRTLQlqrnqlrmlepEPLAGLDQLRELSLAHNRL 458
Cdd:cd00116   256 SLSCNDITDD------GAKDLA-----------EVLAEKESLLELDLRGNKF 290
LRR_8 pfam13855
Leucine rich repeat;
422-475 3.31e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 38.66  E-value: 3.31e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1279652341 422 TGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVgdIGPGTWHELQALQ 475
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT--LSPGAFSGLPSLR 52
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 233-273 7.20e-04

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 37.22  E-value: 7.20e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1279652341 233 TQLRELYLQHNQLTDSGLdattFSKLHSLEYLDLSHNQLTT 273
Cdd:pfam12799   1 PNLEVLDLSNNQITDIPP----LAKLPNLETLDLSGNNKIT 37
LRR_8 pfam13855
Leucine rich repeat;
280-342 8.36e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.50  E-value: 8.36e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1279652341 280 RTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLgsSGLPAGALRPLRGLHTLHLYGNGL 342
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL--TTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
91-174 1.34e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.12  E-value: 1.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  91 SGLRTLNLHNNLISSegLPDEAFESLTQLQHLCVAHNKLSVapqflprslrvadlaanqvmeIFPLTFGEKPALRSVYLH 170
Cdd:pfam13855   1 PNLRSLDLSNNRLTS--LDDGAFKGLSNLKVLDLSNNLLTT---------------------LSPGAFSGLPSLRYLDLS 57


                  ....
gi 1279652341 171 NNQL 174
Cdd:pfam13855  58 GNRL 61
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
70-288 1.61e-03

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 41.30  E-value: 1.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  70 QHLSLQNNQLQELPY--NELSRLSGlrtlnLHNNLISSEGLPdeafeslTQLQHLCVAHNKLSVAPQfLPRSLRVADLAA 147
Cdd:PRK15387  305 QELSVSDNQLASLPAlpSELCKLWA-----YNNQLTSLPTLP-------SGLQELSVSDNQLASLPT-LPSELYKLWAYN 371

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341 148 NQVMEIFPLTFGekpaLRSVYLHNNQLSNAGLPPDAFRgseaiaTLSLSNNQLSYLpPSLPPSLERLHLQNNLISKVPRG 227
Cdd:PRK15387  372 NRLTSLPALPSG----LKELIVSGNRLTSLPVLPSELK------ELMVSGNRLTSL-PMLPSGLLSLSVYRNQLTRLPES 440

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1279652341 228 A--LSRQTQLRelyLQHNQLTDSGLDAttFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLG 288
Cdd:PRK15387  441 LihLSSETTVN---LEGNPLSERTLQA--LREITSAPGYSGPIIRFDMAGASAPRETRALHLA 498
LRR_8 pfam13855
Leucine rich repeat;
138-200 1.71e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 36.73  E-value: 1.71e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1279652341 138 RSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSnaGLPPDAFRGSEAIATLSLSNNQL 200
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLT--TLSPGAFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 70-205 3.84e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 39.83  E-value: 3.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279652341  70 QHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEgLPDEaFESLTQLQHLCVAHNKLSVApqfLPRS------LRVA 143
Cdd:PLN00113  478 ENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGE-IPDE-LSSCKKLVSLDLSHNQLSGQ---IPASfsempvLSQL 552

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1279652341 144 DLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIAT----LSLSNNQLSYLPP 205
Cdd:PLN00113  553 DLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVagniDLCGGDTTSGLPP 618
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
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