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Conserved domains on  [gi|56788359|ref|NP_079284|]
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ADAMTS-like protein 4 isoform 2 precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ADAMTS_spacer1 pfam05986
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ...
 486-599 4.97e-29

ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.


:

Pssm-ID: 461796  Cd Length: 115  Bit Score: 111.90  E-value: 4.97e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   486 LVSGNLTdRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWAVDP-PGSYRAGGTVFRYNRPPREe 564
Cdd:pfam05986   1 TVSGSFT-EGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKNVQGKYILNGKGSISLnPTYPSLLGTVLEYRRSLPA- 78

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 56788359   565 gkGESLSAEGPTTQPVDVYMIFQEE---NPGVFYQYVI 599
Cdd:pfam05986  79 --LEELHAPGPTQEDLEIQVLRQYGkgtNPGITYEYFI 114
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 727-783 7.62e-17

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 75.18  E-value: 7.62e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 56788359   727 WEAGEWTSCSRSCGPGTQHRQLQCRQEfgGGGSSVPPERCGHLPRPNITQSCQLRLC 783
Cdd:pfam19030   1 WVAGPWGECSVTCGGGVQTRLVQCVQK--GGGSIVPDSECSAQKKPPETQSCNLKPC 55
ADAMTS_CR_3 super family cl41950
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ...
 390-484 8.34e-11

ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.


The actual alignment was detected with superfamily member pfam19236:

Pssm-ID: 437068  Cd Length: 115  Bit Score: 60.11  E-value: 8.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   390 QCAAFNSQEFM-----GQLYQW-EPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGAP------DICVAGRCL 457
Cdd:pfam19236   9 QCARTDGQPLRsspggASFYHWgAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPredgtlSLCVLGSCR 88

                          90       100
                  ....*....|....*....|....*..
gi 56788359   458 SPGCDGILGSGRRPDGCGVCGGDDSTC 484
Cdd:pfam19236  89 TFGCDGRMDSQQVWDRCQVCGGDNSTC 115
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 786-841 4.18e-10

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 55.92  E-value: 4.18e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 56788359   786 WEVGsPWSQCSVRCGRGQRSRQVRCVG-NNGDEVSEQECaSGPPQPPSREACDMGPC 841
Cdd:pfam19030   1 WVAG-PWGECSVTCGGGVQTRLVQCVQkGGGSIVPDSEC-SAQKKPPETQSCNLKPC 55
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 143-392 1.18e-05

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.55  E-value: 1.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   143 ARRSRLRDPIKPGMFGYGRVPfalplhrnrRHPRSPPRSELSLISSRGEEAIPSP---TPRAEPFSANGSPQTELPPTEL 219
Cdd:PHA03247 2581 AVTSRARRPDAPPQSARPRAP---------VDDRGDPRGPAPPSPLPPDTHAPDPpppSPSPAANEPDPHPPPTVPPPER 2651

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   220 SVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHHPRA---------QASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWA 290
Cdd:PHA03247 2652 PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAarptvgsltSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQA 2731

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   291 SPQV-AGRRPDPFPSVPRGRGqqGQGPWGTGGTPHGPRLEPDPQHPGA----WLPLLSNGPHASSLWSLFAPSSPIPRCS 365
Cdd:PHA03247 2732 SPALpAAPAPPAVPAGPATPG--GPARPARPPTTAGPPAPAPPAAPAAgpprRLTRPAVASLSESRESLPSPWDPADPPA 2809

                         250       260
                  ....*....|....*....|....*....
gi 56788359   366 GESEQLRA--CSQAPCPPEQPDPRALQCA 392
Cdd:PHA03247 2810 AVLAPAAAlpPAASPAGPLPPPTSAQPTA 2838
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 47-77 2.16e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


:

Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 42.57  E-value: 2.16e-05
                           10        20        30
                   ....*....|....*....|....*....|.
gi 56788359     47 WGPWVQWASCSQPCGVGVQRRSRTCQLPTVQ 77
Cdd:smart00209   1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQ 31
TSP1_ADAMTS super family cl40597
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 674-723 9.13e-04

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


The actual alignment was detected with superfamily member pfam19030:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 38.20  E-value: 9.13e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 56788359   674 SACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPASpEPCHGTPC 723
Cdd:pfam19030   7 GECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPET-QSCNLKPC 55
 
Name Accession Description Interval E-value
ADAMTS_spacer1 pfam05986
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ...
 486-599 4.97e-29

ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.


Pssm-ID: 461796  Cd Length: 115  Bit Score: 111.90  E-value: 4.97e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   486 LVSGNLTdRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWAVDP-PGSYRAGGTVFRYNRPPREe 564
Cdd:pfam05986   1 TVSGSFT-EGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKNVQGKYILNGKGSISLnPTYPSLLGTVLEYRRSLPA- 78

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 56788359   565 gkGESLSAEGPTTQPVDVYMIFQEE---NPGVFYQYVI 599
Cdd:pfam05986  79 --LEELHAPGPTQEDLEIQVLRQYGkgtNPGITYEYFI 114
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 727-783 7.62e-17

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 75.18  E-value: 7.62e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 56788359   727 WEAGEWTSCSRSCGPGTQHRQLQCRQEfgGGGSSVPPERCGHLPRPNITQSCQLRLC 783
Cdd:pfam19030   1 WVAGPWGECSVTCGGGVQTRLVQCVQK--GGGSIVPDSECSAQKKPPETQSCNLKPC 55
ADAMTS_CR_3 pfam19236
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ...
 390-484 8.34e-11

ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.


Pssm-ID: 437068  Cd Length: 115  Bit Score: 60.11  E-value: 8.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   390 QCAAFNSQEFM-----GQLYQW-EPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGAP------DICVAGRCL 457
Cdd:pfam19236   9 QCARTDGQPLRsspggASFYHWgAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPredgtlSLCVLGSCR 88

                          90       100
                  ....*....|....*....|....*..
gi 56788359   458 SPGCDGILGSGRRPDGCGVCGGDDSTC 484
Cdd:pfam19236  89 TFGCDGRMDSQQVWDRCQVCGGDNSTC 115
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 786-841 4.18e-10

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 55.92  E-value: 4.18e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 56788359   786 WEVGsPWSQCSVRCGRGQRSRQVRCVG-NNGDEVSEQECaSGPPQPPSREACDMGPC 841
Cdd:pfam19030   1 WVAG-PWGECSVTCGGGVQTRLVQCVQkGGGSIVPDSEC-SAQKKPPETQSCNLKPC 55
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 786-841 5.31e-06

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 44.50  E-value: 5.31e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 56788359    786 WEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDeVSEQECasgPPQPPSREACDMGPC 841
Cdd:smart00209   1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQ-NGGGPC---TGEDVETRACNEQPC 52
PHA03247 PHA03247
large tegument protein UL36; Provisional
 143-392 1.18e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.55  E-value: 1.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   143 ARRSRLRDPIKPGMFGYGRVPfalplhrnrRHPRSPPRSELSLISSRGEEAIPSP---TPRAEPFSANGSPQTELPPTEL 219
Cdd:PHA03247 2581 AVTSRARRPDAPPQSARPRAP---------VDDRGDPRGPAPPSPLPPDTHAPDPpppSPSPAANEPDPHPPPTVPPPER 2651

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   220 SVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHHPRA---------QASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWA 290
Cdd:PHA03247 2652 PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAarptvgsltSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQA 2731

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   291 SPQV-AGRRPDPFPSVPRGRGqqGQGPWGTGGTPHGPRLEPDPQHPGA----WLPLLSNGPHASSLWSLFAPSSPIPRCS 365
Cdd:PHA03247 2732 SPALpAAPAPPAVPAGPATPG--GPARPARPPTTAGPPAPAPPAAPAAgpprRLTRPAVASLSESRESLPSPWDPADPPA 2809

                         250       260
                  ....*....|....*....|....*....
gi 56788359   366 GESEQLRA--CSQAPCPPEQPDPRALQCA 392
Cdd:PHA03247 2810 AVLAPAAAlpPAASPAGPLPPPTSAQPTA 2838
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 47-77 2.16e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 42.57  E-value: 2.16e-05
                           10        20        30
                   ....*....|....*....|....*....|.
gi 56788359     47 WGPWVQWASCSQPCGVGVQRRSRTCQLPTVQ 77
Cdd:smart00209   1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQ 31
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 674-723 9.13e-04

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 38.20  E-value: 9.13e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 56788359   674 SACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPASpEPCHGTPC 723
Cdd:pfam19030   7 GECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPET-QSCNLKPC 55
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 99-316 1.04e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 42.72  E-value: 1.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359    99 GQGPRPQTSPETLPLYRTQSRGRGGPLRGPAShlgreeTQEIRAARRSRLRDPIKPGMFGYGRVPFALPLHRNRRHPRSP 178
Cdd:pfam09770 164 GVAPKKAAAPAPAPQPAAQPASLPAPSRKMMS------LEEVEAAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFP 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   179 PRSElslissrgeeaiPSPTPRAEPFSANGSPQTELPPTELSvHTPSPQAEPLSPetaqtevAPRTRPAPLRHHPRAQas 258
Cdd:pfam09770 238 PQIQ------------QQQQPQQQPQQPQQHPGQGHPVTILQ-RPQSPQPDPAQP-------SIQPQAQQFHQQPPPV-- 295

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 56788359   259 gtePPSPTHSLgeggffrasPQPRRPSSQGWASPQVAGRRPDPFPSVPRGRGQQGQGP 316
Cdd:pfam09770 296 ---PVQPTQIL---------QNPNRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGR 341
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 727-783 1.25e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 37.57  E-value: 1.25e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 56788359    727 WEAGEWTSCSRSCGPGTQHRQLQCRqefgGGGSSVPPERCGHLPRpnITQSCQLRLC 783
Cdd:smart00209   2 SEWSEWSPCSVTCGGGVQTRTRSCC----SPPPQNGGGPCTGEDV--ETRACNEQPC 52
TSP_1 pfam00090
Thrombospondin type 1 domain;
48-74 2.84e-03

Thrombospondin type 1 domain;


Pssm-ID: 459668 [Multi-domain]  Cd Length: 49  Bit Score: 36.63  E-value: 2.84e-03
                          10        20
                  ....*....|....*....|....*..
gi 56788359    48 GPWVQWASCSQPCGVGVQRRSRTCQLP 74
Cdd:pfam00090   1 SPWSPWSPCSVTCGKGIQVRQRTCKSP 27
PTZ00441 PTZ00441
sporozoite surface protein 2 (SSP2); Provisional
 783-830 3.18e-03

sporozoite surface protein 2 (SSP2); Provisional


Pssm-ID: 240420 [Multi-domain]  Cd Length: 576  Bit Score: 41.10  E-value: 3.18e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 56788359  783 CGHWEvgsPWSQCSVRCGRGQRSRQ-----VRCVGNNGDEVSEQECasgPPQP 830
Cdd:PTZ00441 240 CGPWD---EWTPCSVTCGKGTHSRSrpilhEGCTTHMVEECEEEEC---PVEP 286
 
Name Accession Description Interval E-value
ADAMTS_spacer1 pfam05986
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ...
 486-599 4.97e-29

ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.


Pssm-ID: 461796  Cd Length: 115  Bit Score: 111.90  E-value: 4.97e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   486 LVSGNLTdRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWAVDP-PGSYRAGGTVFRYNRPPREe 564
Cdd:pfam05986   1 TVSGSFT-EGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKNVQGKYILNGKGSISLnPTYPSLLGTVLEYRRSLPA- 78

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 56788359   565 gkGESLSAEGPTTQPVDVYMIFQEE---NPGVFYQYVI 599
Cdd:pfam05986  79 --LEELHAPGPTQEDLEIQVLRQYGkgtNPGITYEYFI 114
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 727-783 7.62e-17

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 75.18  E-value: 7.62e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 56788359   727 WEAGEWTSCSRSCGPGTQHRQLQCRQEfgGGGSSVPPERCGHLPRPNITQSCQLRLC 783
Cdd:pfam19030   1 WVAGPWGECSVTCGGGVQTRLVQCVQK--GGGSIVPDSECSAQKKPPETQSCNLKPC 55
ADAMTS_CR_3 pfam19236
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ...
 390-484 8.34e-11

ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.


Pssm-ID: 437068  Cd Length: 115  Bit Score: 60.11  E-value: 8.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   390 QCAAFNSQEFM-----GQLYQW-EPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGAP------DICVAGRCL 457
Cdd:pfam19236   9 QCARTDGQPLRsspggASFYHWgAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPredgtlSLCVLGSCR 88

                          90       100
                  ....*....|....*....|....*..
gi 56788359   458 SPGCDGILGSGRRPDGCGVCGGDDSTC 484
Cdd:pfam19236  89 TFGCDGRMDSQQVWDRCQVCGGDNSTC 115
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 786-841 4.18e-10

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 55.92  E-value: 4.18e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 56788359   786 WEVGsPWSQCSVRCGRGQRSRQVRCVG-NNGDEVSEQECaSGPPQPPSREACDMGPC 841
Cdd:pfam19030   1 WVAG-PWGECSVTCGGGVQTRLVQCVQkGGGSIVPDSEC-SAQKKPPETQSCNLKPC 55
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 786-841 5.31e-06

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 44.50  E-value: 5.31e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 56788359    786 WEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDeVSEQECasgPPQPPSREACDMGPC 841
Cdd:smart00209   1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQ-NGGGPC---TGEDVETRACNEQPC 52
PHA03247 PHA03247
large tegument protein UL36; Provisional
 143-392 1.18e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.55  E-value: 1.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   143 ARRSRLRDPIKPGMFGYGRVPfalplhrnrRHPRSPPRSELSLISSRGEEAIPSP---TPRAEPFSANGSPQTELPPTEL 219
Cdd:PHA03247 2581 AVTSRARRPDAPPQSARPRAP---------VDDRGDPRGPAPPSPLPPDTHAPDPpppSPSPAANEPDPHPPPTVPPPER 2651

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   220 SVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHHPRA---------QASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWA 290
Cdd:PHA03247 2652 PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAarptvgsltSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQA 2731

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   291 SPQV-AGRRPDPFPSVPRGRGqqGQGPWGTGGTPHGPRLEPDPQHPGA----WLPLLSNGPHASSLWSLFAPSSPIPRCS 365
Cdd:PHA03247 2732 SPALpAAPAPPAVPAGPATPG--GPARPARPPTTAGPPAPAPPAAPAAgpprRLTRPAVASLSESRESLPSPWDPADPPA 2809

                         250       260
                  ....*....|....*....|....*....
gi 56788359   366 GESEQLRA--CSQAPCPPEQPDPRALQCA 392
Cdd:PHA03247 2810 AVLAPAAAlpPAASPAGPLPPPTSAQPTA 2838
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 47-77 2.16e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 42.57  E-value: 2.16e-05
                           10        20        30
                   ....*....|....*....|....*....|.
gi 56788359     47 WGPWVQWASCSQPCGVGVQRRSRTCQLPTVQ 77
Cdd:smart00209   1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQ 31
PHA03247 PHA03247
large tegument protein UL36; Provisional
 94-390 8.29e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 8.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359    94 ALLPRGQGPRPqtsPETLPLYRTQSRGRGGPLRGPASHLGREETQEIRAARRSRLRDPIKPgmfgygrVPFALPLHRNRR 173
Cdd:PHA03247 2616 PLPPDTHAPDP---PPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRA-------AQASSPPQRPRR 2685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   174 HPRSPPRSELSLISSRgeeaiPSPTPRAEPFSANGSPQTELPPTELSVHTPSPQ-----AEPLSPETAQTEVAPRTRPAP 248
Cdd:PHA03247 2686 RAARPTVGSLTSLADP-----PPPPPTPEPAPHALVSATPLPPGPAAARQASPAlpaapAPPAVPAGPATPGGPARPARP 2760

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   249 LRHH-------PRAQASGTEPPSPTHSLGEGGFFRAS-PQPRRPSSQGWASPQVAGRRPD-------------PFPSVPR 307
Cdd:PHA03247 2761 PTTAgppapapPAAPAAGPPRRLTRPAVASLSESRESlPSPWDPADPPAAVLAPAAALPPaaspagplppptsAQPTAPP 2840

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   308 GRGQQGQGPWGTGGT--PHGPRLEPDPQHPGAWLPLLSNGPHASSLWSLFAPSSPIPRCSGESEQLRACSQAPCPPEQPD 385
Cdd:PHA03247 2841 PPPGPPPPSLPLGGSvaPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQ 2920


                  ....*
gi 56788359   386 PRALQ 390
Cdd:PHA03247 2921 PQPPP 2925
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 175-337 1.04e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 46.13  E-value: 1.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359  175 PRSPPRSELSLISSRGEEAIPSPTPRAEPFSANGSPQTELPPTELSVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHHPR 254
Cdd:PRK07764 597 GEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGA 676

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359  255 AQASGTEPPSPTHSLGEGGFFRASPQPRRPssQGWASPQVAGRRPDPfPSVPRGRGQQGQGPWGTGGTPHGPRLEPDPQH 334
Cdd:PRK07764 677 APAAPPPAPAPAAPAAPAGAAPAQPAPAPA--ATPPAGQADDPAAQP-PQAAQGASAPSPAADDPVPLPPEPDDPPDPAG 753


                 ...
gi 56788359  335 PGA 337
Cdd:PRK07764 754 APA 756
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 674-723 9.13e-04

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 38.20  E-value: 9.13e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 56788359   674 SACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPASpEPCHGTPC 723
Cdd:pfam19030   7 GECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPET-QSCNLKPC 55
PHA03247 PHA03247
large tegument protein UL36; Provisional
 100-392 9.36e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 9.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   100 QGPRPQTSPETL-PLYRTQSRGRGGPLRGPASHLGREETQEIRAARRSRLRDPIKPGMFGYGRVPFALPLHRNRRHPRSP 178
Cdd:PHA03247 2681 QRPRRRAARPTVgSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP 2760

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   179 PRSElSLISSRGEEAIPSPTPRAEPFSAnGSPQTELPPTELSVHTPSPQAEPLSPETAQTEVAPR---TRPAPLRHHPRA 255
Cdd:PHA03247 2761 PTTA-GPPAPAPPAAPAAGPPRRLTRPA-VASLSESRESLPSPWDPADPPAAVLAPAAALPPAASpagPLPPPTSAQPTA 2838

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   256 QASGTEPPSPTHSLG----EGGFFRASPQPRRPSSQGWASPQVAGRRPdPFPSVPRGRGQQGQGPWG-----TGGTPHGP 326
Cdd:PHA03247 2839 PPPPPGPPPPSLPLGgsvaPGGDVRRRPPSRSPAAKPAAPARPPVRRL-ARPAVSRSTESFALPPDQperppQPQAPPPP 2917

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56788359   327 RLEPDPQHPGAWLPLLSNGPHASSLWSLFAPSSPIPRCSGESEQLRACSQAPCPPEQPDPRALQCA 392
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPA 2983
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 99-316 1.04e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 42.72  E-value: 1.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359    99 GQGPRPQTSPETLPLYRTQSRGRGGPLRGPAShlgreeTQEIRAARRSRLRDPIKPGMFGYGRVPFALPLHRNRRHPRSP 178
Cdd:pfam09770 164 GVAPKKAAAPAPAPQPAAQPASLPAPSRKMMS------LEEVEAAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFP 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   179 PRSElslissrgeeaiPSPTPRAEPFSANGSPQTELPPTELSvHTPSPQAEPLSPetaqtevAPRTRPAPLRHHPRAQas 258
Cdd:pfam09770 238 PQIQ------------QQQQPQQQPQQPQQHPGQGHPVTILQ-RPQSPQPDPAQP-------SIQPQAQQFHQQPPPV-- 295

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 56788359   259 gtePPSPTHSLgeggffrasPQPRRPSSQGWASPQVAGRRPDPFPSVPRGRGQQGQGP 316
Cdd:pfam09770 296 ---PVQPTQIL---------QNPNRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGR 341
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 727-783 1.25e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 37.57  E-value: 1.25e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 56788359    727 WEAGEWTSCSRSCGPGTQHRQLQCRqefgGGGSSVPPERCGHLPRpnITQSCQLRLC 783
Cdd:smart00209   2 SEWSEWSPCSVTCGGGVQTRTRSCC----SPPPQNGGGPCTGEDV--ETRACNEQPC 52
dnaA PRK14086
chromosomal replication initiator protein DnaA;
173-387 1.42e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 42.12  E-value: 1.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359  173 RHPRSPPRSELSLISSRGEEAIPSPTPRAEPfsangSPQTELPPTELSVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHH 252
Cdd:PRK14086  76 RELGRPIRIAITVDPSAGEPAPPPPHARRTS-----EPELPRPGRRPYEGYGGPRADDRPPGLPRQDQLPTARPAYPAYQ 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359  253 PRAQaSGTEPPSPthslgeggfFRASPQPRR---PSSQGWASPQVAGRRPDPF-PSVPRGRGQQGQgPWGTGGTPhgprl 328
Cdd:PRK14086 151 QRPE-PGAWPRAA---------DDYGWQQQRlgfPPRAPYASPASYAPEQERDrEPYDAGRPEYDQ-RRRDYDHP----- 214

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56788359  329 EPDPQHPGAW---LPLLSNG---PHASSLWSLFAPSSPIPRCSGESEQLRACSQAPCP-PEQPDPR 387
Cdd:PRK14086 215 RPDWDRPRRDrtdRPEPPPGaghVHRGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPgPGEPTAR 280
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 189-303 1.79e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 42.01  E-value: 1.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359  189 RGEEAIPSPTPRAEPFSANGSpqTELPPTElsvhTPSPQAEPLSPETAQTEVAPRTRPAPLRHH-PRAQASGTEPPSPTH 267
Cdd:PRK14951 383 RPEAAAPAAAPVAQAAAAPAP--AAAPAAA----ASAPAAPPAAAPPAPVAAPAAAAPAAAPAAaPAAVALAPAPPAQAA 456

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 56788359  268 SLGEGGFFRASPQPRRPSSQGWASPQVAGRRPDPFP 303
Cdd:PRK14951 457 PETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTE 492
TSP_1 pfam00090
Thrombospondin type 1 domain;
790-841 1.99e-03

Thrombospondin type 1 domain;


Pssm-ID: 459668 [Multi-domain]  Cd Length: 49  Bit Score: 37.01  E-value: 1.99e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 56788359   790 SPWSQCSVRCGRGQRSRQVRCVGNNGDEVSeqeCaSGPPQPpsREACDMGPC 841
Cdd:pfam00090   4 SPWSPCSVTCGKGIQVRQRTCKSPFPGGEP---C-TGDDIE--TQACKMDKC 49
PHA03247 PHA03247
large tegument protein UL36; Provisional
 224-666 2.16e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 2.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   224 PSPQAEPLSPETAQTEVAPRTRPAPLRHHPRAQASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWASPqvAGRRPDPFP 303
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPP--DTHAPDPPP 2628

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   304 SVPRGRGQQGQGPwGTGGTPHGPRLEPDPQHPGAWLP----LLSNGPHASSlwslfAPSSPIPRCSGESEQLRACSQAPC 379
Cdd:PHA03247 2629 PSPSPAANEPDPH-PPPTVPPPERPRDDPAPGRVSRPrrarRLGRAAQASS-----PPQRPRRRAARPTVGSLTSLADPP 2702

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   380 PPE---QPDPRALQCAAfnsqefmgqlyqwePFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGAPDICVAGRC 456
Cdd:PHA03247 2703 PPPptpEPAPHALVSAT--------------PLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPA 2768

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   457 LSPGCDGILGSGRRPDGCGVCGGDDSTCRLVSGNLTDRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIi 536
Cdd:PHA03247 2769 PAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPP- 2847

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56788359   537 ngnwAVDPPGSYRAGGTVFRYNRPPREegkgeslSAEGPTTQPvdvymifqeenpgvfYQYVISSPPPILENPTPEPPVP 616
Cdd:PHA03247 2848 ----PSLPLGGSVAPGGDVRRRPPSRS-------PAAKPAAPA---------------RPPVRRLARPAVSRSTESFALP 2901

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 56788359   617 QLQPEILRVEPPLAPAPRPARTPGTLQRQVRIPQMPAPPHPRTPLGSPAA 666
Cdd:PHA03247 2902 PDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAG 2951
TSP_1 pfam00090
Thrombospondin type 1 domain;
48-74 2.84e-03

Thrombospondin type 1 domain;


Pssm-ID: 459668 [Multi-domain]  Cd Length: 49  Bit Score: 36.63  E-value: 2.84e-03
                          10        20
                  ....*....|....*....|....*..
gi 56788359    48 GPWVQWASCSQPCGVGVQRRSRTCQLP 74
Cdd:pfam00090   1 SPWSPWSPCSVTCGKGIQVRQRTCKSP 27
PTZ00441 PTZ00441
sporozoite surface protein 2 (SSP2); Provisional
 783-830 3.18e-03

sporozoite surface protein 2 (SSP2); Provisional


Pssm-ID: 240420 [Multi-domain]  Cd Length: 576  Bit Score: 41.10  E-value: 3.18e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 56788359  783 CGHWEvgsPWSQCSVRCGRGQRSRQ-----VRCVGNNGDEVSEQECasgPPQP 830
Cdd:PTZ00441 240 CGPWD---EWTPCSVTCGKGTHSRSrpilhEGCTTHMVEECEEEEC---PVEP 286
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 48-70 3.18e-03

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 36.49  E-value: 3.18e-03
                          10        20
                  ....*....|....*....|...
gi 56788359    48 GPWVQWASCSQPCGVGVQRRSRT 70
Cdd:pfam19028   4 SEWSEWSECSVTCGGGVQTRTRT 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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